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Card-index course

Key concepts in immunology/Concepts clÚ de l'immunologie - 29a/CI/SÚrie 3

Responsible Faculty: Doctoral school (FBM-DOCT)

Teacher(s): Werner Held, Ping-Chih Ho

Validity: 2012 ->

No timetable defined.

Tutorial (optional)

Annual

Teaching language(s): English
Public: Yes
Credits: 1.00

Objective

Tutorial in the thematic field "Cancer and Immunology"

Understanding the experimental basis for some of the central concepts in immunology, their molecular explanation today and their applications.

Content

A thorough discussion of selected milestone papers in Immunology.
Each student will introduce and lead the discussion of one key paper covering:
- what was the dogma / the new concept / how was this demonstrated / what was the technological advance needed
- today what is the molecular explanation / what are the implications / applications.
The selection of papers will be discussed with the students, a few ideas are indicated below.

Evaluation

Personal work : Yes
Presentation : Yes
Final Test : No
Participation evaluated by the tutor : Yes

Bibliography

1) K÷hler G, Milstein C. 1975. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature. 1975 256: 495-7. PMID: 1172191

2) Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. 2002. Projection of an immunological self shadow within the thymus by the aire protein. Science. 298:1395-401. PMID: 12376594

3) Gasser S, Orsulic S, Brown EJ, Raulet DH. 2005. The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature. 436: 1186-90. PMID: 15995699

Programme requirements

Basic knowledge in Immunology and Molecular Biology

Grant requirements

The course will be assessed on the basis of active participation.

Access requirements

Registration: via the Doctoral School. Series 3.

Canton de Vaud
Swiss University
Unicentre  -  CH-1015 Lausanne  -  Suisse  -  Tél. +41 21 692 11 11  -  Fax  +41 21 692 26 15