UNIL
le savoir vivant
Vous êtes ici: UNIL > L'enseignement > Fiche de cours
Français | English   Imprimer   

Fiche de cours

Reasoning and Logic in Experimental and Computational Biology - 63/QB/Série 1

Reasoning and logic in experimental and computational biology

Faculté de gestion: Ecole doctorale (FBM-DOCT)

Responsable(s): Paul Franken

Période de validité: 2019 ->

Horaires du cours (Apériodique)

Date Lieu Remarque Thématique Intervenant(s)
07.10.2019 de 16:00 à 18:00 Génopode, room 3027, Quartier UNIL-Sorge Preparation of publication(s) under 3 by students Federico Santoni
10.10.2019 de 16:00 à 18:00 Génopode, room 3027, Quartier UNIL-Sorge Discussion of publication(s) with faculty Federico Santoni
28.10.2019 de 16:00 à 18:00 Génopode, room 3027, Quartier UNIL-Sorge Preparation of publication(s) under 2 by students Alexandre Reymond
30.10.2019 de 16:00 à 18:00 Génopode, room 3027, Quartier UNIL-Sorge Discussion of publication(s) with faculty Alexandre Reymond
18.11.2019 de 16:00 à 18:00 Génopode, room 3027, Quartier UNIL-Sorge Preparation of publication(s) under 1 by students David Gatfield
20.11.2019 de 16:00 à 18:00 Génopode, room 3027, Quartier UNIL-Sorge Discussion of publication(s) with faculty David Gatfield

Tutorial (optionnel)

Annuel
Apériodique
Langue(s) d'enseignement: anglais
Public: Oui
Crédits: 1.00

Objectif

: Tutorial in the thematic field "Integrated Experimental and Computational Biology"

Modern, high throughput data generation methods allow the production of comprehensive data sets and thus a quantitatively unique analysis of many biological phenomena.
The tutorial "Reasoning and Logic in Experimental and Computational Biology" will aim at illustrating the unique conceptual approaches to appropriate experimental design, data analysis and data interpretation required when using high throughput methods.

Contenu

Presentation and discussion of published examples of the application of high throughput DNA sequencing and other genomic methods, applied to a range of different biological questions.

Evaluation

Travail personnel de préparation: Oui
Présentation personnelle: Oui
Test final : Non
Evaluation de la participation par l'enseignant :Oui

Bibliographie

1) Non-optimal codon usage affects expression, structure and function of clock protein FRQ. Zhou et al. Nature 2013 [PMID: 23417067] and "Non-optimal codon usage is a mechanism to achieve circadian clock conditionality" Xu et al. Nature 2013 [PMID: 23417065]

2) "A de novo paradigm for mental retardation" Vissers et al. Nat Genetics 2010 [PMID: 21076407] and "Genome sequencing identifies major causes of severe intellectual disability" Gilissen et al. Nature 2014 [PMID: 24896178]

3) "Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population" Wu et al. Cell 2014 [PMID: 25215496]

Exigences du cursus d'études

Aucun

Conditions d'octroi

Evaluation positive de la participation active par le tuteur.

Conditions d'accès

Inscription auprès de l'Ecole doctorale. Série 1.

Canton de Vaud
Swiss University
Unicentre  -  CH-1015 Lausanne  -  Suisse  -  Tél. +41 21 692 11 11  -  Fax  +41 21 692 26 15