Card-index course
Origin and consequences of the human microbiota imbalance on health - 47a/Série 4
Responsible Faculty: Doctoral school (FBM-DOCT)
Teacher(s): Hélène Niculita Hirzel, Pascale Vonaesch
No timetable defined.
Tutorial (optional)
Annual
Teaching language(s): English
Public: Yes
Credits: 1
Objective
The objective of this tutorial is to familiarize the students with the diversity of microbiomes living in symbiosis with humans and illustrate the estalblishemtn of the community and the consequences on health of a disruption in their homeostasis. The tutorial also aims to acquire a critical view on the complexity of the factors that act on microbiota homeostasis. While the tutorial focuses on human microbiomes, it's also open the discussion on their interaction with environmental microbiomes.
Content
The tutorial will address the one health concept to identify the factors acting on human microbiomes. After a presentation of this concept, we will read and discuss key articles on balance and dysbiosis of human microbiomes.
Each student will introduce and open the discussion around a key article concerning:
- a dogma / new concept / technological progress
- a disruptive factor
- a pathological consequence of the dysfunction
A summary will take into account the importance of the one health concept in controlling the possible emergence of new pathologies.
Evaluation
Personal work: Yes
Presentation: Yes
Final test final: No
Evaluation of participation by tutor: Yes
Bibliography
1) Berg G et al. 2020. Microbiome definition re-visited: old concepts and new challenges. Microbiome. 8(1):103. doi: 10.1186/s40168-020-00875-0.
2) Cani PD. 2018. Human gut microbiome: hopes, threats and promises. Gut. 67(9):1716-1725. doi: 10.1136/gutjnl-2018-316723.
3) Lloyd-Price J et al. 2016. The healthy human microbiome.Genome Med. 8(1):51. doi: 10.1186/s13073-016-0307-y.
Specific articles to be presented by the students will be shared approximately a week before the start of the tutorial
Programme requirements
Basic knowledge in microbiology and / or ecology
Access requirements
Registration: via the Doctoral School. Period 4