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Card-index course

Origin and consequences of the human microbiota imbalance on health - 47a/Série 4

Responsible Faculty: Doctoral school (FBM-DOCT)

Teacher(s): Hélène Niculita Hirzel, Pascale Vonaesch

Validity: 2021 -> 2023

No timetable defined.

Tutorial (optional)

Annual

Teaching language(s): English
Public: Yes
Credits: 1

Objective

The objective of this tutorial is to familiarize the students with the diversity of microbiomes living in symbiosis with humans and illustrate the estalblishemtn of the community and the consequences on health of a disruption in their homeostasis. The tutorial also aims to acquire a critical view on the complexity of the factors that act on microbiota homeostasis. While the tutorial focuses on human microbiomes, it's also open the discussion on their interaction with environmental microbiomes.

Content

The tutorial will address the one health concept to identify the factors acting on human microbiomes. After a presentation of this concept, we will read and discuss key articles on balance and dysbiosis of human microbiomes.
Each student will introduce and open the discussion around a key article concerning:
- a dogma / new concept / technological progress
- a disruptive factor
- a pathological consequence of the dysfunction
A summary will take into account the importance of the one health concept in controlling the possible emergence of new pathologies.

Evaluation

Personal work: Yes
Presentation: Yes
Final test final: No
Evaluation of participation by tutor: Yes

Bibliography

1)  Berg G et al. 2020. Microbiome definition re-visited: old concepts and new challenges. Microbiome. 8(1):103. doi: 10.1186/s40168-020-00875-0.

2)  Cani PD. 2018. Human gut microbiome: hopes, threats and promises. Gut. 67(9):1716-1725. doi: 10.1136/gutjnl-2018-316723.

3) Lloyd-Price J et al. 2016. The healthy human microbiome.Genome Med. 8(1):51. doi: 10.1186/s13073-016-0307-y.

Specific articles to be presented by the students will be shared approximately a week before the start of the tutorial

Programme requirements

Basic knowledge in microbiology and / or ecology

Access requirements

Registration: via the Doctoral School. Period 4

Unicentre - CH-1015 Lausanne - Suisse
Tél. +41 21 692 11 11
Canton de Vaud
Swiss University