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Card-index course

Tumor immune microenvironment:concepts, techniques and therapeutic targeting/Microenvironnement tumoral immunitaire: concepts, techniques et ciblage thérapeutique - 51/Série 2

Responsible Faculty: Doctoral school (FBM-DOCT)

Teacher(s): Alejandra Gonzalez Loyola, Tatiana Petrova

Validity: 2020 ->

Course Timetable (Aperiodic)

Date Location Notice Topics Lecturer(s)
2021-02-02 de 15:00 à 17:00 Room B-305, Centre des Laboratoires d'Epalinges, Chemin des Boveresses 155, 1066 Epalinges Exploring the immune cell landscape in cancer Johanna Joyce
2021-02-09 de 15:00 à 17:00 Room B-305, Centre des Laboratoires d'Epalinges, Chemin des Boveresses 155, 1066 Epalinges Harnessing the tumor microenvironment to enhance T-cell therapy Melita Irving

Tutorial

Annual
Aperiodic
Teaching language(s): English
Public: Yes
Credits: 1

Objective

The tumor microenvironment (TME) - vessels, immune cells, fibroblasts and signalling mediators- is crucial for growth of cancer cells. It also represents an important therapeutic target exemplified by recent progress in cancer immune therapies. The goals of this tutorial are to:
-provide overview of the key players of the TME
-discuss the role of the TME in tumor progression and metastasis
-give an overview of current and potential future therapeutic interventions targeting the TME with a focus on immune therapies

Content

First session will be an introductory lecture on tumor microenvironment and distribution of selected key papers in the TME among the participants. Following sessions: 3 student presentations per session. Each student will present and discuss the paper selected on a journal club basis (25 min + 10 min questions). Each session will end with a group discussion and a summary by a tutor.

Evaluation

Personal preparation work : Yes
Personal presentation : Yes
Final test final: No
Evaluation of participation by tutor: Yes

If the tutorial can not to be given in-person class it will take place via zoom
The organiser will apply for credits for continuous education in animal experimentation to RESAL.

Bibliography

1) Petrova TV, Koh GY. Science. 2020 Jul 10;369(6500) Biological functions of lymphatic vessels.

2) De Palma M, Biziato D, Petrova TV. Nat Rev Cancer. 2017 Aug;17(8):457-474. Microenvironmental regulation of tumour angiogenesis.

3) Joyce JA, Fearon DT.Science. 2015 Apr 3;348(6230):74-80. T cell exclusion, immune privilege, and the tumor microenvironment.

Programme requirements

1.Motivation to learn more about cancer biology in general and the tumor microenvironment. 2.Basic knowledge of molecular and cellular biology, physiology. 3. Tutorial will be given in English

Access requirements

Registration: via the Doctoral School. Period 2

Additional information

https://www.unil.ch/dof/petrova

Use contextFaculty codeStatusCredits
Doctorate in Life Sciences (2003 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Life Sciences - Cancer and Immunology (2008 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Life Sciences - Cardiovascular and Metabolism (2005 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Life Sciences - Ecology and Evolution (2007 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Life Sciences - Integrated Experimental and Computational Biology (2010 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Life Sciences - Microbial Sciences (2010 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Life Sciences - Quantitative Biology (2018 ->) ›› TutorialsED-FBMOptional1.00
Doctorate in Medecine and Sciences (MD-PhD) (2010 ->) ›› TutorialsED-FBMOptional1.00
PhD in the Humanities and Social Sciences of Medicine (2021 ->) ›› TutorialsED-FBMOptional1.00
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