Research directions
Therapeutic eduction in cystic fibrosis
Normative values infant lung function
Development of normative values of lung function measurements in infants
Early diagnosis of ABPA in CF
The diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis (CF) is a challenge. Thymus- and activation-regulated chemokine (TARC) has recently been reported to play a role in ABPA.
Aim: evaluation of thymus- and activation-regulated chemokine as an marker for early diagnosis of ABPA in CF patients.
New clinical scoring system Cystic Fibrosis
The proposed project will extend our preliminary work with the Royal Children's Hospital in developing a Cystic Fibrosis (CF) severity scale from the RCH CF database of patient and disease characteristics.
We previously identified an approach for developing a severity scale based on feature selection. We now propose to refine this scale by using a hybrid model combining mathematical and statistical approaches:
