Laurence de Leval

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350 publications

2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | ...
SARS-CoV-2 ACE-receptor detection in the placenta throughout pregnancy.
Gengler C., Dubruc E., Favre G., Greub G., de Leval L., Baud D., 2021/03. Clinical microbiology and infection, 27 (3) pp. 489-490. Peer-reviewed.
In Situ Characterization of Follicular Helper CD4 T Cells Using Multiplexed Imaging.
Ioannidou K., Ndiaye D.R., Noto A., Fenwick C., Fortis S.P., Pantaleo G., Petrovas C., de Leval L., 2021/02/28. Frontiers in immunology, 11 p. 607626. Peer-reviewed.
Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future.
Hofman P., Ilié M., Chamorey E., Brest P., Schiappa R., Nakache V., Antoine M., Barberis M., Begueret H., Bibeau F. et al., 2021/02. ESMO open, 6 (1) p. 100024. Peer-reviewed.
Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer.
Cachot A., Bilous M., Liu Y.C., Li X., Saillard M., Cenerenti M., Rockinger G.A., Wyss T., Guillaume P., Schmidt J. et al., 2021/02. Science advances, 7 (9) pp. eabe3348. Peer-reviewed.
Integrative analysis of a phase 2 trial combining lenalidomide with CHOP in angioimmunoblastic T-cell lymphoma.
Lemonnier F., Safar V., Beldi-Ferchiou A., Cottereau A.S., Bachy E., Cartron G., Fataccioli V., Pelletier L., Robe C., Letourneau A. et al., 2021/01/26. Blood advances, 5 (2) pp. 539-548. Peer-reviewed.
Recent advances upper gastrointestinal lymphomas: molecular updates and diagnostic implications.
Foukas P.G., Bisig B., de Leval L., 2021/01. Histopathology, 78 (1) pp. 187-214. Peer-reviewed.
A randomized phase 3 trial of auto vs. allo transplantation as part of first-line therapy in poor-risk peripheral T-NHL.
Schmitz N., Truemper L.H., Bouabdallah K., Ziepert M., Leclerc M., Cartron G., Jaccard A., Reimer P., Wagner-Drouet E.M., Wilhelm M. et al., 2020/12/17. Blood. Peer-reviewed.
Chromosomes in breast lymphoma.
de Leval L., 2020/12/17. Blood, 136 (25) pp. 2848-2849. Peer-reviewed.
Cytokine-directed therapy with tocilizumab for immune checkpoint inhibitor-related hemophagocytic lymphohistiocytosis.
Özdemir B.C., Latifyan S., Perreau M., Fenwick C., Alberio L., Waeber G., Spertini F., de Leval L., Michielin O., Obeid M., 2020/12. Annals of oncology, 31 (12) pp. 1775-1778. Peer-reviewed.
Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma in Asia Frequently Shows SETD2 Alterations.
Tomita S., Kikuti Y.Y., Carreras J., Sakai R., Takata K., Yoshino T., Bea S., Campo E., Missiaglia E., Bouilly J. et al., 2020/11/27. Cancers, 12 (12) p. 3539. Peer-reviewed.
Multisystem inflammatory syndrome with refractory cardiogenic shock due to acute myocarditis and mononeuritis multiplex after SARS-CoV-2 infection in an adult.
Othenin-Girard A., Regamey J., Lamoth F., Horisberger A., Glampedakis E., Epiney J.B., Kuntzer T., de Leval L., Carballares M., Hurni C.A. et al., 2020/11/02. Swiss medical weekly, 150 pp. w20387. Peer-reviewed.
Controversies in the Treatment of Peripheral T-cell Lymphoma.
Bachy E., Broccoli A., Dearden C., de Leval L., Gaulard P., Koch R., Morschhauser F., Trümper L., Zinzani P.L., 2020/10. HemaSphere, 4 (5) pp. e461. Peer-reviewed.
MarrowQuant Across Aging and Aplasia: A Digital Pathology Workflow for Quantification of Bone Marrow Compartments in Histological Sections.
Tratwal J., Bekri D., Boussema C., Sarkis R., Kunz N., Koliqi T., Rojas-Sutterlin S., Schyrr F., Tavakol D.N., Campos V. et al., 2020/09/24. Frontiers in endocrinology, 11 p. 480. Peer-reviewed.
Meningeal Relapse of Nodular Lymphocyte Predominant Hodgkin Lymphoma Transformed to T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Case Report.
Salvioni Chiabotti P., Bisig B., Cairoli A., Hajdu S.D., Lovey P.Y., Milowich D., Ziadi S., Du Pasquier R., Brouland J.P., de Leval L., 2020/09/14. Frontiers in oncology, 10 p. 1745. Peer-reviewed.
Solute carrier family 12 member 2 as a proteomic and histological biomarker of dysplasia and neoplasia in ulcerative colitis.
Merli A.M., Vieujean S., Massot C., Blétard N., Quesada Calvo F., Baiwir D., Mazzucchelli G., Servais L., Wéra O., Oury C. et al., 2020/09/13. Journal of Crohn's & colitis. Peer-reviewed.
Management of Patients With Hematologic Malignancies During the COVID-19 Pandemic: Practical Considerations and Lessons to Be Learned.
Isidori A., de Leval L., Gergis U., Musto P., Porcu P., 2020/08/01. Frontiers in oncology, 10 p. 1439. Peer-reviewed.
Lymph node involvement by enteropathy-like indolent NK-cell proliferation.
Dargent J.L., Tinton N., Trimech M., de Leval L., 2020/07/21. Virchows Archiv. Peer-reviewed.
Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract.
Soderquist C.R., Patel N., Murty V.V., Betman S., Aggarwal N., Young K.H., Xerri L., Leeman-Neill R., Lewis S.K., Green P.H. et al., 2020/07. Haematologica, 105 (7) pp. 1895-1906. Peer-reviewed.
Defining signatures of peripheral T-cell lymphoma with a targeted 20-marker gene expression profiling assay.
Drieux F., Ruminy P., Abdel-Sater A., Lemonnier F., Viailly P.J., Fataccioli V., Marchand V., Bisig B., Letourneau A., Parrens M. et al., 2020/06. Haematologica, 105 (6) pp. 1582-1592. Peer-reviewed.
Lymphoma Classification.
de Leval L., Jaffe E.S., 2020/05/31. Cancer journal, 26 (3) pp. 176-185. Peer-reviewed.
Lymphocyte predominant cells detect Moraxella catarrhalis-derived antigens in nodular lymphocyte-predominant Hodgkin lymphoma.
Thurner L., Hartmann S., Fadle N., Regitz E., Kemele M., Kim Y.J., Bohle R.M., Nimmesgern A., von Müller L., Kempf VAJ et al., 2020/05/18. Nature communications, 11 (1) p. 2465. Peer-reviewed.
A Diffuse Medullary Hypercaptation With No Bone Lesion.
Christin A., de Leval L., Obeid M., 2020/02/01. JAMA oncology, 6 (2) pp. 291-292. Peer-reviewed.
Approach to nodal-based T-cell lymphomas.
de Leval L., 2020/01. Pathology, 52 (1) pp. 78-99. Peer-reviewed.
Reproducing the molecular subclassification of peripheral T-cell lymphoma-NOS by immunohistochemistry.
Amador C., Greiner T.C., Heavican T.B., Smith L.M., Galvis K.T., Lone W., Bouska A., D'Amore F., Pedersen M.B., Pileri S. et al., 2019/12/12. Blood, 134 (24) pp. 2159-2170. Peer-reviewed.
The Romand Network of Oncology: bridging the gap of personalised oncology
Michielin O., Tsantoulis P., Homicsko K., Christinat Y., De Leval L., Bisig B., Missiaglia E., Zoete V., Krebs F., Fortin A. et al., 2019/10/18. Swiss Medical Weekly.
New Data in the Molecular Pathology of T-Cell Lymphomas
De Leval L., 2019/09/30. Leading Opinions Hämatologie und Onkologie, 15 (5) pp. 43-45.
Microfluidic-based immunohistochemistry for breast cancer diagnosis: a comparative clinical study.
Aimi F., Procopio M.G., Alvarez Flores M.T., Brouland J.P., Piazzon N., Brajkovic S., Dupouy D.G., Gijs M., de Leval L., 2019/09. Virchows Archiv, 475 (3) pp. 313-323. Peer-reviewed.
<sup>18</sup>F-FDG PET metabolic-to-morphological volume ratio predicts PD-L1 tumour expression and response to PD-1 blockade in non-small-cell lung cancer.
Jreige M., Letovanec I., Chaba K., Renaud S., Rusakiewicz S., Cristina V., Peters S., Krueger T., de Leval L., Kandalaft L.E. et al., 2019/08. European journal of nuclear medicine and molecular imaging, 46 (9) pp. 1859-1868. Peer-reviewed.
Clinical spectrum, evolution, and management of autoimmune cytopenias associated with angioimmunoblastic T-cell lymphoma.
Crickx E., Poullot E., Moulis G., Goulabchand R., Fieschi C., Galicier L., Meignin V., Coppo P., Delarue R., Casasnovas O. et al., 2019/07. European journal of haematology, 103 (1) pp. 35-42. Peer-reviewed.
Lymph node migratory dendritic cells modulate HIV-1 transcription through PD-1 engagement.
Banga R., Rebecchini C., Procopio F.A., Noto A., Munoz O., Ioannidou K., Fenwick C., Ohmiti K., Cavassini M., Corpataux J.M. et al., 2019/07. PLoS pathogens, 15 (7) pp. e1007918. Peer-reviewed.
Breast implant-associated anaplastic large cell lymphoma and other rare T-cell lymphomas.
de Leval L., 2019/06. Hematological oncology, 37 Suppl 1 pp. 24-29. Peer-reviewed.
Crystal-Storing Histiocytosis.
Rebecchini C., Trimeche M., Rosselet A., de Leval L., 2019/06. International journal of surgical pathology, 27 (4) pp. 399-400. Peer-reviewed.
Primary hepatic marginal B cell lymphoma of mucosa-associated lymphoid tissue (MALT) and non-alcoholic steatohepatitis (NASH): more than a coincidence?
Haefliger S., Milowich D., Sciarra A., Trimeche M., Bouilly J., Kaiser J., Volpi S., Brouland J.P., Sempoux C., de Leval L., 2019/06. Annals of hematology, 98 (6) pp. 1513-1516. Peer-reviewed.
High-content, cell-by-cell assessment of HER2 overexpression and amplification: a tool for intratumoral heterogeneity detection in breast cancer.
Nguyen H.T., Migliozzi D., Bisig B., de Leval L., Gijs MAM, 2019/05. Laboratory investigation; a journal of technical methods and pathology, 99 (5) pp. 722-732. Peer-reviewed.
Genetic drivers of oncogenic pathways in molecular subgroups of peripheral T-cell lymphoma.
Heavican T.B., Bouska A., Yu J., Lone W., Amador C., Gong Q., Zhang W., Li Y., Dave B.J., Nairismägi M.L. et al., 2019/04/11. Blood, 133 (15) pp. 1664-1676. Peer-reviewed.
CD73 expression in normal and pathological human hepatobiliopancreatic tissues.
Sciarra A., Monteiro I., Ménétrier-Caux C., Caux C., Gilbert B., Halkic N., La Rosa S., Romero P., Sempoux C., de Leval L., 2019/03. Cancer immunology, immunotherapy, 68 (3) pp. 467-478. Peer-reviewed.
Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues
Sciarra Amedeo, Monteiro Inês, Ménétrier-Caux Christine, Caux Christophe, Gilbert Benoit, Halkic Nermin, La Rosa Stefano, Romero Pedro, Sempoux Christine, de Leval Laurence, 2019/03. 1.
CCND2 and CCND3 hijack immunoglobulin light-chain enhancers in cyclin D1<sup>-</sup> mantle cell lymphoma.
Martín-Garcia D., Navarro A., Valdés-Mas R., Clot G., Gutiérrez-Abril J., Prieto M., Ribera-Cortada I., Woroniecka R., Rymkiewicz G., Bens S. et al., 2019/02/28. Blood, 133 (9) pp. 940-951. Peer-reviewed.
The Need for a Consensus Next-generation Sequencing Panel for Mature Lymphoid Malignancies
Sujobert P., Le Bris Y., de Leval L., Gros A., Merlio JP, Pastoret C., Huet S., Sarkozy C., Davi F., Callanan M. et al., 2019/02. HemaSphere, 3 (1) pp. e169. Peer-reviewed.
Pathology and Molecular Pathogenesis of T-Cell Lymphoma
Iqbal J., De Leval L., 2019/01/31. pp. 95-141 dans Agressive Lymphomas chap. 4, Springer.
Cyclin D1-positive Mediastinal Large B-Cell Lymphoma With Copy Number Gains of CCND1 Gene: A Study of 3 Cases With Nonmediastinal Disease.
Chen B.J., Ruminy P., Roth C.G., Bisig B., Mankel B., Steinhilber J., Bohers E., Jardin F., Fend F., Swerdlow S.H. et al., 2019/01. The American journal of surgical pathology, 43 (1) pp. 110-120. Peer-reviewed.
Fetal Anthropometric Features: A Postmortem Study of Fetuses After the Termination of Pregnancy for Psychosocial Reasons Between 12 and 20 Gestational Weeks.
Muller Brochut A.C., Taffe P., Piaget-Rossel R., de Leval L., Rougemont A.L., 2019. Pediatric and developmental pathology, 22 (3) pp. 243-251. Peer-reviewed.
IG-MYC+ neoplasms with precursor B-cell phenotype are molecularly distinct from Burkitt lymphomas
Wagener R., López C., Kleinheinz K., Bausinger J., Aukema S.M., Nagel I., Toprak U.H., Seufert J., Altmüller J., Thiele H. et al., 2018/11/22. Blood, 132 (21) pp. 2280-2285. Peer-reviewed.
Advancing synoptic cancer reports beyond English: the University of Bern/PathoLink approach.
Banz Y., Berezowska S., de Leval L., Rubbia-Brandt L., Tolnay M., Moch H., Perren A., Hewer E., 2018/11. Virchows Archiv, 473 (5) pp. 655-656. Peer-reviewed.
Dual JAK1 and STAT3 mutations in a breast implant-associated anaplastic large cell lymphoma.
Letourneau A., Maerevoet M., Milowich D., Dewind R., Bisig B., Missiaglia E., de Leval L., 2018/10. Virchows Archiv, 473 (4) pp. 505-511. Peer-reviewed.
Multiple Ways to Detect IDH2 Mutations in Angioimmunoblastic T-Cell Lymphoma from Immunohistochemistry to Next-Generation Sequencing.
Dupuy A., Lemonnier F., Fataccioli V., Martin-Garcia N., Robe C., Pelletier R., Poullot E., Moktefi A., Mokhtari K., Rousselet M.C. et al., 2018/09. The Journal of molecular diagnostics, 20 (5) pp. 677-685. Peer-reviewed.
New insights in the pathogenesis of T-cell lymphomas.
Lemonnier F., Gaulard P., de Leval L., 2018/09. Current opinion in oncology, 30 (5) pp. 277-284. Peer-reviewed.
RNA fusions involving CD28 are rare in peripheral T-cell lymphomas and concentrate mainly in those derived from follicular helper T cells.
Vallois D., Dupuy A., Lemonnier F., Allen G., Missiaglia E., Fataccioli V., Ortonne N., Clavert A., Delarue R., Rousselet M.C. et al., 2018/08. Haematologica, 103 (8) pp. e360-e363. Peer-reviewed.
CD73 expression and clinical significance in human metastatic melanoma.
Monteiro I., Vigano S., Faouzi M., Treilleux I., Michielin O., Ménétrier-Caux C., Caux C., Romero P., de Leval L., 2018/06/01. Oncotarget, 9 (42) pp. 26659-26669. Peer-reviewed.
A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine.
Herfs M., Roncarati P., Koopmansch B., Peulen O., Bruyere D., Lebeau A., Hendrick E., Hubert P., Poncin A., Penny W. et al., 2018/05. British journal of cancer, 118 (10) pp. 1302-1312. Peer-reviewed.
AMPK promotes survival of c-Myc-positive melanoma cells by suppressing oxidative stress.
Kfoury A., Armaro M., Collodet C., Sordet-Dessimoz J., Giner M.P., Christen S., Moco S., Leleu M., de Leval L., Koch U. et al., 2018/03/01. The EMBO journal, 37 (5) pp. e97673. Peer-reviewed.
Comment on "MEK inhibition with trametinib and tyrosine kinase inhibition with imatinib in multifocal histiocytic sarcoma".
Voruz S., Martins F., Cairoli A., Naveiras O., Homicsko K., Missiaglia E., de Leval L., Bisig B., Michielin O., Blum S., 2018/03. Haematologica, 103 (3) pp. e130. Peer-reviewed.
Loss of 5-hydroxymethylcytosine is a frequent event in peripheral T-cell lymphomas.
Lemonnier F., Poullot E., Dupuy A., Couronné L., Martin N., Scourzic L., Fataccioli V., Bruneau J., Cairns R.A., Mak T.W. et al., 2018/03. Haematologica, 103 (3) pp. e115-e118. Peer-reviewed.
Definition of a minimal genes set for mature lymphoid blood diseases [Définition d'un panel minimal de gènes pour la· prise en charge des hémopathies lymphoïdes matures]
Sujobert P., Le Bris Y., de Leval L., Gros A., Merlio JP, Pastoret C., Huet S., Sarkozy C., Davi F., Callanan M. et al., 2018/02/28. Hématologie, 24 (1) pp. 27-59. Peer-reviewed.
Breast Implant-Associated Malignant Lymphoma
De Leval Laurence, Milowich Dina, 2018. pp. 1-6 dans Encyclopedia of Pathology, Springer International Publishing.
Low 5-year cumulative incidence of post-transplant lymphoproliferative disorders after solid organ transplantation in Switzerland.
Steiner R., Kridel R., Giostra E., McKee T., Achermann R., Mueller N., Manuel O., Dickenmann M., Schuurmans M.M., de Leval L. et al., 2018. Swiss medical weekly, 148 pp. w14596. Peer-reviewed.
Non-Hodgkin Lymphomas: Pathology and Genetics
de Leval L., 2018. pp. 48-75 dans Encyclopedia of Cancer, Elsevier.
Response to MEK inhibition with trametinib and tyrosine kinase inhibition with imatinib in multifocal histiocytic sarcoma.
Voruz S., Cairoli A., Naveiras O., de Leval L., Missiaglia E., Homicsko K., Michielin O., Blum S., 2018/01. Haematologica, 103 (1) pp. e39-e41. Peer-reviewed.
Human papillomavirus oncoproteins induce a reorganization of epithelial-associated γδ T cells promoting tumor formation.
Van Hede D., Polese B., Humblet C., Wilharm A., Renoux V., Dortu E., de Leval L., Delvenne P., Desmet C.J., Bureau F. et al., 2017/10/24. Proceedings of the National Academy of Sciences of the United States of America, 114 (43) pp. E9056-E9065. Peer-reviewed.
P 14: RNA fusions involving CD28 contribute to mutations-induced TCR signaling activation in peripheral T-cell lymphomas of TFH derivation
Vallois D., Dupuy A., Lemonnier F., Fataccioli V., Ortonne N., Allen G., Tournilhac O., Delarue R., Rousselet MC, Fabiani B. et al., 2017/10/20. pp. 578-579 dans Swiss Pathology Days, Der Pathologe.
P13: Breast implant-associated anaplastic large-cell lymphoma presenting as a tumor mass and recurring as a seroma, with dual JAK1 and STAT3 mutations
Bisig B., Letourneau A., Maerevoet M., Millowich D., Dewind R., Missiaglia E., de Leval L., 2017/10/20. p. 578 dans Swiss Pathology Days, Der Pathologe.
B-cell lymphomas with discordance between pathological features and clinical behavior
de Leval Laurence, Copie-Bergman Christiane, Rosenwald Andreas, Rimsza Lisa, Pittaluga Stefania, Bisig Bettina, Dirnhofer Stefan, Facchetti Fabio, Pileri Stefano, Fend Falko et al., 2017/10. Virchows Archiv, 471 (4) pp. 439-451. Peer-reviewed.
Impact of human papillomavirus on outcome in patients with oropharyngeal cancer treated with primary surgery.
Broglie M.A., Stoeckli S.J., Sauter R., Pasche P., Reinhard A., de Leval L., Huber G.F., Pezier T.F., Soltermann A., Giger R. et al., 2017/10. Head & neck, 39 (10) pp. 2004-2015. Peer-reviewed.
A standardized quantification tool for bone marrow components in histological sections
Tratwal J., Boussema C., Burri O., Koliqi T., Campos V., Nardi V., Bárcena C., Sarro R., Bisig B., De Leval L., 2017/09. pp. S62-S63 dans Experimental Hematology, Elsevier BV.
The clinicopathologic spectrum of mature aggressive B cell lymphomas.
Rimsza L., Pittaluga S., Dirnhofer S., Copie-Bergman C., de Leval L., Facchetti F., Pileri S., Rosenwald A., Wotherspoon A., Fend F., 2017/08/26. Virchows Archiv, 471 (4) pp. 453-466. Peer-reviewed.
Microfluidics for rapid cytokeratin immunohistochemical staining in frozen sections.
Brajkovic S., Dupouy D.G., de Leval L., Gijs M.A., 2017/08. Laboratory investigation; a journal of technical methods and pathology, 97 (8) pp. 983-991. Peer-reviewed.
Histiocytic and dendritic cell neoplasms: what have we learnt by studying 67 cases.
Facchetti F., Pileri S.A., Lorenzi L., Tabanelli V., Rimsza L., Pittaluga S., Dirnhofer S., Copie-Bergman C., de Leval L., Rosenwald A. et al., 2017/07/10. Virchows Archiv, 471 (4) pp. 467-489. Peer-reviewed.
Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy.
Darcis G., Van der Auwera G., Giot J.B., Hayette M.P., Tassin F., Arrese Estrada J., Cnops L., Moutschen M., de Leval L., Leonard P., 2017/07/07. BMC infectious diseases, 17 (1) p. 478. Peer-reviewed.
Immunoregulation of Dendritic Cell Subsets by Inhibitory Receptors in Urothelial Cancer.
Chevalier M.F., Bohner P., Pieraerts C., Lhermitte B., Gourmaud J., Nobile A., Rotman S., Cesson V., Martin V., Legris A.S. et al., 2017/06. European urology, 71 (6) pp. 854-857. Peer-reviewed.
Very low expression of PD-L1 in medullary thyroid carcinoma.
Bongiovanni M., Rebecchini C., Saglietti C., Bulliard J.L., Marino L., de Leval L., Sykiotis G.P., 2017/06. Endocrine-related cancer, 24 (6) pp. L35-L38. Peer-reviewed.
Du neuf dans l’oncogenèse moléculaire des lymphomes : rôle du gène SETD2 dans les lymphomes T de l’intestin [Molecular oncogenesis of lymphomas: role of the SETD2 gene in intestinal T-cell lymphomas]
Vallois D., Roberti A., Bisig B., Gaulard P., de Leval L., 2017/05. Medecine sciences, 33 (5) pp. 469-473. Peer-reviewed.
Fibrin-Associated EBV plus Large B-Cell Lymphoma: An Indolent Neoplasm Distinct from DLBCL-CI [1363]
Boyer D., McKelvie P., de Leval L., Edlefsen KL, Ko YH, Aberman Z., Kovach A., Masih A., Nishino A., Weiss L. et al., 2017/04/30., 106th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP) pp. 339A-340A dans Modern Pathology.
Fibrin-associated EBV-positive Large B-Cell Lymphoma: An Indolent Neoplasm With Features Distinct From Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation.
Boyer D.F., McKelvie P.A., de Leval L., Edlefsen K.L., Ko Y.H., Aberman Z.A., Kovach A.E., Masih A., Nishino H.T., Weiss L.M. et al., 2017/04. The American journal of surgical pathology, 41 (3) pp. 299-312. Peer-reviewed.
Integrative clinicopathological and molecular analyses of angioimmunoblastic T-cell lymphoma and other nodal lymphomas of follicular helper T-cell origin.
Dobay M.P., Lemonnier F., Missiaglia E., Bastard C., Vallois D., Jais J.P., Scourzic L., Dupuy A., Fataccioli V., Pujals A. et al., 2017/04. Haematologica, 102 (4) pp. e148-e151. Peer-reviewed.
The Genetic Basis of Hepatosplenic T-cell Lymphoma.
McKinney M., Moffitt A.B., Gaulard P., Travert M., De Leval L., Nicolae A., Raffeld M., Jaffe E.S., Pittaluga S., Xi L. et al., 2017/04. Cancer discovery, 7 (4) pp. 369-379. Peer-reviewed.
How I manage peripheral T-cell lymphoma, not otherwise specified and angioimmunoblastic T-cell lymphoma: current practice and a glimpse into the future.
Schmitz N., de Leval L., 2017/03. British journal of haematology, 176 (6) pp. 851-866. Peer-reviewed.
IgG4-Related Disease Causing Rapid Evolution of a Severe Aortic Valvular Stenosis.
Bruls S., Courtois A., Delvenne P., Hustinx R., Moutschen M., De Leval L., Defraigne J.O., Sakalihasan N., 2017/03. The Annals of thoracic surgery, 103 (3) pp. e239-e240. Peer-reviewed.
Azacytidine prevents experimental xenogeneic graft-versus-host disease without abrogating graft-versus-leukemia effects.
Ehx G., Fransolet G., de Leval L., D'Hondt S., Lucas S., Hannon M., Delens L., Dubois S., Drion P., Beguin Y. et al., 2017. Oncoimmunology, 6 (5) pp. e1314425. Peer-reviewed.
Microfluidics-assisted fluorescence in situ hybridization for advantageous human epidermal growth factor receptor 2 assessment in breast cancer.
Nguyen H.T., Trouillon R., Matsuoka S., Fiche M., de Leval L., Bisig B., Gijs M.A., 2017/01. Laboratory investigation; a journal of technical methods and pathology, 97 (1) pp. 93-103. Peer-reviewed.
The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
Lemonnier F., Cairns R.A., Inoue S., Li W.Y., Dupuy A., Broutin S., Martin N., Fataccioli V., Pelletier R., Wakeham A. et al., 2016/12/27. Proceedings of the National Academy of Sciences of the United States of America, 113 (52) pp. 15084-15089. Peer-reviewed.
Cutaneous presentation of hepatosplenic T-cell lymphoma-a potential mimicker of primary cutaneous gamma-delta T-cell lymphoma.
Karpate A., Barcena C., Hohl D., Bisig B., de Leval L., 2016/11. Virchows Archiv : an international journal of pathology, 469 (5) pp. 591-596. Peer-reviewed.
Kontrastverstärkter Ultraschall einer nodulären extramedullären Hämatopoese der Milz bei einem Patienten mit primärer Myelofibrose [Contrast-Enhanced Ultrasound of Nodular Splenic Extramedullary Hematopoiesis in a Patient with Underlying Primary Myelofibrosis]
Hajdu S.D., de Leval L., Meuwly J.Y., 2016/10. Ultraschall in der Medizin, 37 (5) pp. 447-450. Peer-reviewed.
PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals.
Banga R., Procopio F.A., Noto A., Pollakis G., Cavassini M., Ohmiti K., Corpataux J.M., de Leval L., Pantaleo G., Perreau M., 2016/07. Nature medicine, 22 (7) pp. 754-761. Peer-reviewed.
Oropharyngeal NK/T-cell lymphoma presenting with bilateral uveitis.
Grosjean P., Thiry A., De Leval L., Bonnet S., 2016/03. Journal francais d'ophtalmologie, 39 (3) pp. e57-8. Peer-reviewed.
Continuous quantification of HER2 expression by microfluidic precision immunofluorescence estimates HER2 gene amplification in breast cancer.
Dupouy D.G., Ciftlik A.T., Fiche M., Heintze D., Bisig B., de Leval L., Gijs M.A., 2016/02/09. Scientific reports, 6 p. 20277. Peer-reviewed.
Breast implant-associated anaplastic large cell lymphoma: two distinct clinicopathological variants with different outcomes.
Laurent C., Delas A., Gaulard P., Haioun C., Moreau A., Xerri L., Traverse-Glehen A., Rousset T., Quintin-Roue I., Petrella T. et al., 2016/02. Annals of oncology : official journal of the European Society for Medical Oncology, 27 (2) pp. 306-314. Peer-reviewed.
Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.
Vallois D., Dobay M.P., Morin R.D., Lemonnier F., Missiaglia E., Juilland M., Iwaszkiewicz J., Fataccioli V., Bisig B., Roberti A. et al., 2016. Blood, 128 (11) pp. 1490-1502.
ALK-negative anaplastic large-cell lymphoma.
Gaulard P., de Leval L., 2016. Blood, 127 (2) pp. 175-177. Peer-reviewed.
Azacytidine Enhances Regulatory T-Cells In Vivo and Prevents Experimental Xenogeneic Graft-Versus-Host Disease
Ehx G., Fransolet G., De Leval L., D'Hondt S., Lucas S., Hannon M., Delens L., Dubois S., Drion P., Beguin Y. et al., 2016. pp. S393-S393 dans BMT Tandem Meetings, Biology of Blood and Marrow Transplantation. Peer-reviewed.
Fatal Outcome of Multiple Clinical Presentations of Human Herpesvirus 8-related Disease After Solid Organ Transplantation.
Vijgen S., Wyss C., Meylan P., Bisig B., Letovanec I., Manuel O., Pascual M., de Leval L., 2016. Transplantation, 100 (1) pp. 134-140. Peer-reviewed.
Follicular lymphoma
Harris NL, De Leval L., Louissaint A., Ferry JA, 2016. pp. 321-352 dans Hematopathology chap. 18, Elsevier.
Peripheral T-Cell Lymphoma, Not Otherwise Specified
De Leval L., 2016. pp. 641-658 dans Hematopathology chap. 35, Elsevier.
Prognostic value of baseline total metabolic tumor volume (TMTV0) measured on FDG-PET/CT in patients with peripheral T-cell lymphoma (PTCL).
Cottereau A.S., Becker S., Broussais F., Casasnovas O., Kanoun S., Roques M., Charrier N., Bertrand S., Delarue R., Bonnet C. et al., 2016. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo, 27 (4) pp. 719-724. Peer-reviewed.
Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations.
Roberti A., Dobay M.P., Bisig B., Vallois D., Boéchat C., Lanitis E., Bouchindhomme B., Parrens M.C., Bossard C., Quintanilla-Martinez L. et al., 2016. Nature Communications, 7 p. 12602. Peer-reviewed.
Artérite de Horton: recommandations Lausannoises de prise en charge [Giant cell arteritis: guidelines of the University Hospital of Lausanne].
Tsetsou S., Michel P., Ribi C., Hirt L., Kawasaki A., Hugli O., De Leval L., Bart P.A., Waeber G., Meuli R. et al., 2015/02. Revue Médicale Suisse, 11 (461) pp. 411-417.
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells.
Küçük C., Jiang B., Hu X., Zhang W., Chan J.K., Xiao W., Lack N., Alkan C., Williams J.C., Avery K.N. et al., 2015. Nature Communications, 6 p. 6025. Peer-reviewed.
Anaplastic large cell lymphoma and other rare mature T- and NK-cell lymphomas
Lamant L., Gaulard P., Chan JKC, Jaffe ES, Nakamura S., Molina TJ, De Leval L., 2015. pp. - dans WHO classification of tumours of the lung, pleura, thymus and heart, World Health Organization.
Angioimmunoblastic T-cell lymphoma is the most common T-cell lymphoma in two distinct French information data sets.
de Leval L., Parrens M., Le Bras F., Jais J.P., Fataccioli V., Martin A., Lamant L., Delarue R., Berger F., Arbion F. et al., 2015. Haematologica, 100 (9) pp. e361-e364. Peer-reviewed.
Cerebriforms cells in cerebrum: an unusual finding
Sarro R., Gaide O., Letourneau A., Missiaglia E., Bisig B., Hottinger A., Cairoli A., de Leval L., 2015. p. 633 dans 81. Jahrestagung der Schweizerischen Gesellschaft für Pathologie, Der Pathologe.
IA02: Principles of lymphoma classification
De Leval L., 2015. pp. - dans AACR Special Conference on Hematologic Malignancies - Translating Discoveries to Novel Therapies, Clinical Cancer Research. Peer-reviewed.
KLF2 mutation is the most frequent somatic change in splenic marginal zone lymphoma and identifies a subset with distinct genotype.
Clipson A., Wang M., de Leval L., Ashton-Key M., Wotherspoon A., Vassiliou G., Bolli N., Grove C., Moody S., Escudero-Ibarz L. et al., 2015. Leukemia, 29 (5) pp. 1177-1185. Peer-reviewed.
Lymphoblastic transformation of follicular lymphoma: a clinicopathologic and molecular analysis of 7 patients.
Geyer J.T., Subramaniyam S., Jiang Y., Elemento O., Ferry J.A., de Leval L., Nakashima M.O., Liu Y.C., Martin P., Mathew S. et al., 2015. Human Pathology, 46 (2) pp. 260-271. Peer-reviewed.
Lymphocytic variant hypereosinophilic syndrome progressing to angioimmunoblastic T-cell lymphoma.
Roufosse F., de Leval L., van Krieken H., van Deuren M., 2015. Leukemia and Lymphoma, 56 (6) pp. 1891-1894. Peer-reviewed.
Plasma cell and terminal B-cell differentiation in mantle cell lymphoma mainly occur in the SOX11-negative subtype.
Ribera-Cortada I., Martinez D., Amador V., Royo C., Navarro A., Beà S., Gine E., de Leval L., Serrano S., Wotherspoon A. et al., 2015. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc, 28 (11) pp. 1435-1447. Peer-reviewed.
Recent advances in intestinal lymphomas.
Foukas P.G., de Leval L., 2015. Histopathology, 66 (1) pp. 112-136.
The microenvironment in T-cell lymphomas
De Leval L., Gaulard P., 2015. pp. 112-131 dans Hodgkin And Non-Hodgkin Lymphomas Seen Through Their Microenvironment: Impact on Diagnosis, Prognosis and Innovative Therapy chap. 8, Future Medicine Ltd.
Immunohistochemistry as a valuable tool to assess CD30 expression in peripheral T-cell lymphomas: high correlation with mRNA levels.
Bossard C., Dobay M.P., Parrens M., Lamant L., Missiaglia E., Haioun C., Martin A., Fabiani B., Delarue R., Tournilhac O. et al., 2014/11/06. Blood, 124 (19) pp. 2983-2986. Peer-reviewed.
Current Issues in the Diagnosis and Classification of Peripheral T-Cell Lymphomas
Nolan G., de Leval L., Feldman A., Swerdlow SH, Cerroni L., 2014/03. dans Annual Meeting 2014 of Society for Hematopathology.
Accuracy of sentinel lymph node dissection for melanoma staging in the presence of a collision tumour with a lymphoproliferative disease.
Gero D., Queiros da Mota V., Boubaker A., Berthod G., de Leval L., Demartines N., Matter M., 2014. Melanoma Research, 24 (4) pp. 371-376.
Cellular origin of T-cell lymphomas.
de Leval L., Gaulard P., 2014. Blood, 123 (19) pp. 2909-2910.
Conjunctival MALT lymphoma: utility of FDG PET/CT for diagnosis, staging, and evaluation of treatment response.
Sallak A., Besson F.L., Pomoni A., Christinat A., Adler M., Aegerter J.P., Nguyen C., de Leval L., Frossard V., Prior J.O., 2014. Clinical Nuclear Medicine, 39 (3) pp. 295-297.
Cytotoxic T-cell and NK-cell Lymphomas: Current Questions and Controversies.
Swerdlow S.H., Jaffe E.S., Brousset P., Chan J.K., de Leval L., Gaulard P., Harris N.L., Pileri S., Weiss L.M., International Lymphoma Study Group, 2014. American Journal of Surgical Pathology, 38 (10) pp. e60-e71.
Diagnosis of malignant lymphomas in 2014: Part. 2: T-cell lymphomas
De Leval L., 2014. dans XXXth Congress of the International Academy of Pathology (IAP) 2014.
Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma
Iqbal J., Wright G., Wang C., Rosenwald A., Gascoyne R.D., Weisenburger D.D., Greiner T.C., Smith L., Guo S., Wilcox R.A. et al., 2014. Blood, 123 (19) pp. 2915-2923. Peer-reviewed.
Haematopathology: MYC or not MYC? All you need to know about MYC-driven aggressive B-cell lymphomas : presentation of three cases
de Leval L., 2014. dans 26th European Congress of Pathology.
ITMIG consensus statement on the use of the WHO histological classification of thymoma and thymic carcinoma: refined definitions, histological criteria, and reporting.
Marx A., Ströbel P., Badve S.S., Chalabreysse L., Chan J.K., Chen G., de Leval L., Detterbeck F., Girard N., Huang J. et al., 2014. Journal of Thoracic Oncology, 9 (5) pp. 596-611. Peer-reviewed.
Nodal T-cell lymphomas with a TFH phenotype, AITL and Related TFH Nodal Tumors
de Leval L., 2014. dans 2014 Annual Meeting of Society for Hematopathology.
Pathology of peripheral T-cell lymphomas: where do we stand?
Gaulard P., de Leval L., 2014. Seminars In Hematology, 51 (1) pp. 5-16.
Peripheral T-cell lymphoma with t(6;14)(p25;q11.2) translocation presenting with massive splenomegaly.
Somja J., Bisig B., Bonnet C., Herens C., Siebert R., de Leval L., 2014. Virchows Archiv, 464 (6) pp. 735-741. Peer-reviewed.
Pitfalls in the diagnosis of non-Hodgkin's lymphomas
De Leval L., Barcena C., 2014. pp. 245-256 dans Abutalib S.A., Markman M. (eds.) Cancer consult : expertise for clinical practice chap. 38, Wiley.
Primary γδ T cell lymphoma of the lung: report of a case with features suggesting derivation from intraepithelial γδ T lymphocytes [Primary gammadelta T cell lymphoma of the lung: report of a case with features suggesting derivation from intraepithelial gammadelta T lymphocytes].
Choe J.Y., Bisig B., de Leval L., Jeon Y.K., 2014. Virchows Archiv : An International Journal of Pathology, 465 (6) pp. 731-736. Peer-reviewed.
Purpura of the face and neck: an atypical clinical presentation revealing a hepatosplenic T cell lymphoma
Kuonen F., Bucher M., de Leval L., Vernez M., Gilliet M., Conrad C., Feldmeyer L., 2014. Case Reports in Dermatology, 6 (1) pp. 37-42. Peer-reviewed.
The microenvironment in T-cell lymphomas: Emerging themes
Gaulard P., de Leval L., 2014. Seminars In Cancer Biology, 24 pp. 49-60. Peer-reviewed.
Typing less common ovarian tumors: A training tool based on a pattern-based algorithm applied to a set of 20 virtual slides.
Vjigen S., Saravia M., Granger P., Devouassoux M., de Leval L., Fiche M., 2014. dans 12th European Congress on Digital Pathology.
CD30 in PTCLS: correlation between RNA and protein levels in a large european series from the LYSA
Bossard C., Dobay M.P., Lamant L., Missiglia E., Parrens M., Martin A., Tournillac C., Haioun C., Bonnet C., Berger F. et al., 2013/06. pp. 146-147 dans 12th International Conference on Malignant Lymphoma, Hematological Oncology.
Clinicopathologic and histologic characteristics of angioimmunoblastic T-cell lymphoma: analysis of 231 patients of the tenomic project from the LYSA. In Clinicopathologic correlations (184)
Le Bras F., Parrens M., de Leval L., Lemonnier F., Couronne L., Bernard A., Bastard C., Cairns R.A., Mak T.W., Jais J. et al., 2013/06., 12th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, June 19-22, 2013 p. 158 dans Hematological Oncology, Wiley Blackwell.
CD30-positive peripheral T-cell lymphomas share molecular and phenotypic features.
Bisig B., de Reyniès A., Bonnet C., Sujobert P., Rickman D.S., Marafioti T., Delsol G., Lamant L., Gaulard P., de Leval L., 2013. Haematologica, 98 (8) pp. 1250-1258.
Clinicopathologic analysis of acute myeloid leukemia arising from chronic myelomonocytic leukemia.
Courville E.L., Wu Y., Kourda J., Roth C.G., Brockmann J., Muzikansky A., Fathi A.T., de Leval L., Orazi A., Hasserjian R.P., 2013. Modern Pathology, 26 (6) pp. 751-761. Peer-reviewed.
EBV+ cutaneous B-cell lymphoproliferation of the leg in an elderly patient with mycosis fungoides and methotrexate treatment.
Rausch T., Cairoli A., Benhattar J., Spring P., Hohl D., de Leval L., 2013. Apmis : Acta Pathologica, Microbiologica, et Immunologica Scandinavica, 121 (1) pp. 79-84.
Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production.
Perreau M., Savoye A.L., De Crignis E., Corpataux J.M., Cubas R., Haddad E.K., De Leval L., Graziosi C., Pantaleo G., 2013. Journal of Experimental Medicine, 210 (1) pp. 143-156. Peer-reviewed.
Immunophenotyping of non-Hodgkin lymphomas
Gloghini A., De Leval L., 2013. pp. 32-55 dans Non-Hodgkin Lymphomas: Advanced Diagnostics & Personalized Therapies chap. 3, Future Medicine.
Impact of bone marrow-derived mesenchymal stromal cells on experimental xenogeneic graft-versus-host disease.
Bruck F., Belle L., Lechanteur C., de Leval L., Hannon M., Dubois S., Castermans E., Humblet-Baron S., Rahmouni S., Beguin Y. et al., 2013. Cytotherapy, 15 (3) pp. 267-279. Peer-reviewed.
Localized amyloid light-chain amyloidosis and extramedullary plasmacytoma of the mitral valve.
Roumy A., de Leval L., Niclauss L., Schaefer S.C., Kurtin P., Dogan A., von Segesser L.K., Ruchat P., 2013. Annals of Thoracic Surgery, 95 (5) pp. 1782-1784.
Molecular and Clinical Aspects of Angioimmunoblastic T-Cell Lymphoma
De Leval L., Foss F., Gaulard P., 2013. pp. 57-69 dans T-Cell Lymphomas chap. 4, Springer.
Molecular underpinning of extranodal NK/T-cell lymphoma.
Huang Y., de Leval L., Gaulard P., 2013. Best Practice and Research. Clinical Haematology, 26 (1) pp. 57-74.
Recurrent loss of heterozygosity in 1p36 associated with TNFRSF14 mutations in IRF4 translocation negative pediatric follicular lymphomas.
Martin-Guerrero I., Salaverria I., Burkhardt B., Szczepanowski M., Baudis M., Bens S., de Leval L., Garcia-Orad A., Horn H., Lisfeld J. et al., 2013. Haematologica, 98 (8) pp. 1237-1241.
ROQUIN/RC3H1 alterations are not found in angioimmunoblastic T-cell lymphoma.
Auguste T., Travert M., Tarte K., Amé-Thomas P., Artchounin C., Martin-Garcia N., de Reynies A., de Leval L., Gaulard P., Delfau-Larue M.H., 2013. Plos One, 8 (6) pp. e64536.
Splenic Marginal Zone Lymphoma: Mutation Landscape by Exome Sequencing
Clipson AJ, Watkins AJ, Ashton-Key M., de Leval L., Wotherspoon A., Vassiliou G., Du MQ, 2013. p. 21 dans 7th Joint Meeting of the British-Division of the International-Academy-of-Pathology and the Pathological-Society-of-Great-Britain-and-Ireland, Journal of Pathology.
VIII. New markers in peripheral T-cell lymphomas: more entities or more confusion?
Gaulard P., de Leval L., 2013. Hematological Oncology, 31 (Suppl. 1) pp. 51-56.
Diffuse large B-cell lymphoma of Waldeyer's ring has distinct clinicopathologic features: a GELA study.
de Leval L., Bonnet C., Copie-Bergman C., Seidel L., Baia M., Brière J., Molina T.J., Fabiani B., Petrella T., Bosq J. et al., 2012/12. Annals of Oncology, 23 (12) pp. 3143-3151. Peer-reviewed.
An unusual phyllodes tumour of the prostate (FP17)
Fontanella S., Fritschi U., Jichlinski P., deLeval L., Rotman S., 2012/11., 78. Annual Meeting of the Swiss Society of Pathology. St. Gallen, Switzerland, 8.-10. November 2012 pp. 575-576 dans Der Pathologe, Springer Medizin.
Angioimmunoblastic T-Cell Lymphoma (AITL) Is the Most Prevalent T-Cell Lymphoma Entity in Western Europe
Parrens M, Martin A, Lamant L, Delarue R, Haioun C, Tournilhac O, Berger F, Bossard C, Bouchind'homme B, Briere J et al., 2012/11. dans Blood.
Follicular Peripheral T-cell Lymphoma Expands the Spectrum of Classical Hodgkin Lymphoma Mimics.
Moroch J., Copie-Bergman C., de Leval L., Plonquet A., Martin-Garcia N., Delfau-Larue M.H., Molinier-Frenkel V., Belhadj K., Haioun C., Audouin J. et al., 2012/11. American Journal of Surgical Pathology, 36 (11) pp. 1636-1646. Peer-reviewed.
An Unusual Uterine Tumor With Signet Ring Cell Features.
Sarro R., Fiche M., Bisig B., Ketterer N., Benhattar J., Achtari C., de Leval L., 2012/03. International Journal of Gynecological Pathology, 31 (3) pp. 236-241.
An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rγnull mice allows HIV replication and development of anti-HIV immune responses.
Singh M., Singh P., Gaudray G., Musumeci L., Thielen C., Vaira D., Vandergeeten C., Delacroix L., Van Gulck E., Vanham G. et al., 2012. Plos One, 7 (6) pp. e38491.
An integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma.
Watkins A.J., Hamoudi R.A., Zeng N., Yan Q., Huang Y., Liu H., Zhang J., Braggio E., Fonseca R., de Leval L. et al., 2012. Plos One, 7 (9) pp. e44997. Peer-reviewed.
Angioimmunoblastic T-cell lymphoma (AITL) is the most prevalent T-cell lymphoma entity in Western Europe (LYS005)
Parrens M., Martin A., Lamant L., Delarue R., Berger F., Abion F., Bossard C., Bouchindhomme B., Brière J., Canioni D. et al., 2012., Lymphopath Network and the T-cell lymphoma Tenomic Consortium p. 216 dans XVI meeting of the European Association for Haematopathology 2012 Abstracts, Journal of Hematopathology.
c-Maf expression in angioimmunoblastic T-cell lymphoma reflects follicular helper T-cell derivation rather than oncogenesis.
Bisig B., Thielen C., Herens C., Gofflot S., Travert M., Delfau-Larue M.H., Boniver J., Gaulard P., de Leval L., 2012. Histopathology, 60 (2) pp. 371-376. Peer-reviewed.
Cardiac paraganglioma: diagnostic work up and review of the literature.
Sook M., Hamoir E., de Leval L., Duquenne S., Larbuisson R., Joris J., Meurisse M., Defraigne J., Radermecker M.A., 2012. Acta Chirurgica Belgica, 112 (4) pp. 310-313.
CD30 expression in peripheral T-cell lymphomas, not otherwise specified: is it relevant for the identification of distinct subgroups?(LYS011)
Bisig B., de Leval L., Risckman D.S., Sujobert P., Bonnet Ch., Marafioti T., Delsol G., Lamant L., Gaulard Ph., 2012. pp. 220-221 dans XVI Meeting of the European Association for Haematopathology 2012, Journal of Hematopathology.
Genetic aberrations in pediatric follicular lymphoma
Martin-Guerrero I., Salaverria I., Burkhardt B., Szczepanowski M., Garcia-Orad A., Pellissery S., Bens S., Mann F., de Leval L., Lisfeld J. et al., 2012. p. 1044 dans SIOP 2012, 44th Congress of the International Society of Paediatric Oncology, Pediatric Blood and Cancer.
Genetic aberrations in pediatric follicular lymphoma
Martin-Guerrero I., Salaverria I., Burkhardt B., Szczepanowski M., Garcia-Orad A., Pellissery S., Bens S., Mann F, de Leval L., Lisfeld J. et al., 2012. p. 20 dans 4th International Symposium on Childhood, Adolescent and Young Adult Non-Hodgkin's Lymphoma, British Journal of Haematology.
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma.
Cairns R.A., Iqbal J., Lemonnier F., Kucuk C., de Leval L., Jais J.P., Parrens M., Martin A., Xerri L., Brousset P. et al., 2012. Blood, 119 (8) pp. 1901-1903.
Infliximab Therapy for a Severe Case of IgG4-related Ocular Adnexal Disorder Recalcitrant to Corticosteroid Treatment.
Balaskas K., de Leval L., La Corte R., Zografos L., Guex-Crosier Y., 2012. Ocular Immunology and Inflammation, 20 (6) pp. 478-480. Peer-reviewed.
Interpretation of needle biopsies of the kidney for investigation of renal masses.
Lhermitte B., de Leval L., 2012. Virchows Archiv, 461 (1) pp. 13-26.
Lymphoid Tumours of the Stomach
De Leval L., 2012. pp. 241-269 dans Morson and Dawson's Gastrointestinal Pathology chap. 15, Wiley.
Lymphoproliferative disorders associated with hypereosinophilia.
Roufosse F., Garaud S., de Leval L., 2012. Seminars In Hematology, 49 (2) pp. 138-148.
Molecular features of hepatosplenic T-cell lymphoma unravels potential novel therapeutic targets.
Travert M., Huang Y., de Leval L., Martin-Garcia N., Delfau-Larue M.H., Berger F., Bosq J., Brière J., Soulier J., Macintyre E. et al., 2012. Blood, 119 (24) pp. 5795-5806.
New biomarkers in T-cell lymphomas.
Bisig B., Gaulard P., de Leval L., 2012. Best Practice and Research. Clinical Haematology, 25 (1) pp. 13-28. Peer-reviewed.
Recurrent mutations in TET2, IDH2 and DNMT3 genes regulating DNA methylation in Peripheral T-cell Lymphomas correlate with TFH-like features and clinical parameters(LYS006)
Lemonnier F., Couronné L., Parrens M., Jais J.-P., Travert M., Lamant L., Tournillac O., Rousset Th., Fabiani B., Martin A. et al., 2012. pp. 217-218 dans XVI Meeting of the European Association for Haematopathology 2012, Journal of Hematopathology.
Recurrent TET2 mutations in peripheral T-cell lymphomas correlate with TFH-like features and adverse clinical parameters.
Lemonnier F., Couronné L., Parrens M., Jaïs J.P., Travert M., Lamant L., Tournillac O., Rousset T., Fabiani B., Cairns R.A. et al., 2012. Blood, 120 (7) pp. 1466-1469. Peer-reviewed.
Small nucleolar RNA expression profiling identifies potential prognostic markers in peripheral T-cell lymphoma.
Valleron W., Ysebaert L., Berquet L., Fataccioli V., Quelen C., Martin A., Parrens M., Lamant L., de Leval L., Gisselbrecht C. et al., 2012. Blood, 120 (19) pp. 3997-4005. Peer-reviewed.
Surgical treatment of cardiovascular complications in patients with Marfan syndrome: a report of two cases and literature review.
Bruls S., Radermecker M.A., Creemers E., Bonnet P., Nellessen E., Van Damme H., De Leval L., Defraigne J.O., 2012. Acta Chirurgica Belgica, 112 (3) pp. 213-218.
t(X;14)(p11.4;q32.33) is recurrent in marginal zone lymphoma and up-regulates GPR34.
Baens M., Finalet Ferreiro J., Tousseyn T., Urbankova H., Michaux L., de Leval L., Dierickx D., Wolter P., Sagaert X., Vandenberghe P. et al., 2012. Haematologica, 97 (2) pp. 184-188. Peer-reviewed.
Targeting intratumoral B cells with rituximab in addition to CHOP in angioimmunoblastic T-cell lymphoma. A clinicobiological study of the GELA.
Delfau-Larue M.H., de Leval L., Joly B., Plonquet A., Challine D., Parrens M., Delmer A., Salles G., Morschhauser F., Delarue R. et al., 2012. Haematologica, 97 (10) pp. 1594-1602. Peer-reviewed.
The impact of cyclin D1 mRNA isoforms, morphology and p53 in mantle cell lymphoma: p53 alterations and blastoid morphology are strong predictors of a high proliferation index.
Slotta-Huspenina J., Koch I., de Leval L., Keller G., Klier M., Bink K., Kremer M., Raffeld M., Fend F., Quintanilla-Martinez L., 2012. Haematologica, 97 (9) pp. 1422-1430.
Type II enterpathy-associated T-cell lymphoma: report of a european series(LYS018)
de Leval L., Parrens M., Bouchindhomme B., Moreau A., Bossard C., Molina Th., Delfau M.-H., Gaulard Ph., 2012. pp. 225-226 dans XVI Meeting of the European Association for Haematopathology 2012, Journal of hematopathology.
Follicular lymphoma with initial manifestation as bone lesions: a report of three cases.
Kourda J., Letovanec I., de Leval L., 2011/11., Schweizerische Gesellschaft für Pathologie: 77. Annual meeting of the Swiss Society of Pathology, Luzern, 10. -12 November 2011 pp. 543 / PO33 dans Organ der Deutschen Abteilung der Internationalen Akademie für Pathologie der Deutschen der Österreichischen und der Schweizerischen Gesellschaft für Pathologie und des Berufsverbandes Deutscher Pathologen (eds.) Der Pathologe, Sonderdruck.
Régression spontanée d'un lymphome B à grandes cellules du palais [Hard palate B cell lymphoma with spontaneous regression]
Brachet P., de Leval L., Chantrain G., Loeb I., Saussez S., 2011/06. Revue de stomatologie et de chirurgie maxillo-faciale, 112 (3) pp. 180-182. Peer-reviewed.
BCR and TLR signalling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas.
Yan Y., Huang Y., Watkins A.J., Kocialkowski S., Zeng N., Hamoudi R.A., Isaacson P.G., de Leval L., Wotherspoon A., Du M.Q., 2011. Haematologica pp. -. Peer-reviewed.
BM-573 inhibits the development of early atherosclerotic lesions in Apo E deficient mice by blocking TP receptors and thromboxane synthase.
Cherdon C., Rolin S., Hanson J., Ooms A., de Leval L., Drion P., Michiels C., Pirotte B., Masereel B., Sakalihassan N. et al., 2011. Prostaglandins and Other Lipid Mediators, 94 (3-4) pp. 124-132. Peer-reviewed.
CHIC cells: a novel ALK+ cell line derived from a relapsed anaplastic large cell lymphoma.
Thielen C., Bisig B., Gofflot S., Herens C., Fillet G., Jamar M., Tassin F., Boniver J., Drion P., de Leval L., 2011. British Journal of Haematology, 152 (3) pp. 356-360.
Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study.
Jaccard A., Gachard N., Marin B., Rogez S., Audrain M., Suarez F., Tilly H., Morschhauser F., Thieblemont C., Ysebaert L. et al., 2011. Blood, 117 (6) pp. 1834-1839.
Follicular helper T cells: implications in neoplastic hematopathology.
Gaulard P., de Leval L., 2011. Seminars in Diagnostic Pathology, 28 (3) pp. 202-213.
Genomic, Epigenomic and Transcriptomic Molecular Characterization of Splenic Marginal Zone Lymphoma Reveals Recurrent Abnormalities in miR-182
Watkins A. J., Hamoudi R., de Leval L., Wotherspoon A., Isaacson P. G., Du M.-.Q., 2011. pp. S23 dans 199th Scientific Meeting of the Pathological-Society-of-Great-Britain-and-Ireland, Journal of Pathology. Peer-reviewed.
Identification of stromal proteins overexpressed in nodular sclerosis Hodgkin lymphoma.
Kischel P., Waltregny D., Greffe Y., Mazzucchelli G., De Pauw E., de Leval L., Castronovo V., 2011. Proteome Science, 9 (1) p. 63. Peer-reviewed.
International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 1: specimen handling.
Samaratunga H., Montironi R., True L., Epstein J.I., Griffiths D.F., Humphrey P.A., van der Kwast T., Wheeler T.M., Srigley J.R., Delahunt B. et al., 2011/01. Modern pathology, 24 (1) pp. 6-15. Peer-reviewed.
International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 2: T2 substaging and prostate cancer volume.
van der Kwast T.H., Amin M.B., Billis A., Epstein J.I., Griffiths D., Humphrey P.A., Montironi R., Wheeler T.M., Srigley J.R., Egevad L. et al., 2011/01. Modern pathology, 24 (1) pp. 16-25. Peer-reviewed.
International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease.
Magi-Galluzzi C., Evans A.J., Delahunt B., Epstein J.I., Griffiths D.F., van der Kwast T.H., Montironi R., Wheeler T.M., Srigley J.R., Egevad L.L. et al., 2011/01. Modern pathology, 24 (1) pp. 26-38. Peer-reviewed.
International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes.
Berney D.M., Wheeler T.M., Grignon D.J., Epstein J.I., Griffiths D.F., Humphrey P.A., van der Kwast T., Montironi R., Delahunt B., Egevad L. et al., 2011/01. Modern pathology, 24 (1) pp. 39-47. Peer-reviewed.
International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins.
Tan P.H., Cheng L., Srigley J.R., Griffiths D., Humphrey P.A., van der Kwast T.H., Montironi R., Wheeler T.M., Delahunt B., Egevad L. et al., 2011/01. Modern pathology, 24 (1) pp. 48-57. Peer-reviewed.
Le cas clinique du mois. A propos d'un cas de séquestration pulmonaire intralobaire diagnostiqué à l'âge adulte [Clinical case of the month. Intrapulmonary lung sequestration diagnosed in an adult].
Somja J., De Leval L., Boniver J., Radermecker M.A., 2011. Revue Médicale De Liège, 66 (1) pp. 7-12.
Pathology and biology of peripheral T-cell lymphomas.
de Leval L., Gaulard P., 2011. Histopathology, 58 (1) pp. 49-68.
PRDM1 is a tumor suppressor gene in natural killer cell malignancies.
Küçük C., Iqbal J., Hu X., Gaulard P., De Leval L., Srivastava G., Au W.Y., McKeithan T.W., Chan W.C., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (50) pp. 20119-20124.
Primary central nervous system lymphoma in a patient treated with natalizumab.
Phan-Ba R., Bisig B., Deprez M., De Prijck B., Delrue G., Herens C., Moonen G., Belachew S., de Leval L., 2011. Annals of Neurology, 69 (6) pp. 1060-1; author reply 1061-2.
Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential.
Remmelink M., de Leval L., Decaestecker C., Duray A., Crompot E., Sirtaine N., André S., Kaltner H., Leroy X., Gabius H.J. et al., 2011. Histopathology, 58 (4) pp. 543-556. Peer-reviewed.
The Distinct Molecular Signature Of Hepatosplenic T-Cell Lymphoma (Hstl) Identifies Oncogenic Pathways With Potential Therapeutic Relevance
Travert M., Huang Y., De Reynies A., De Leval L., Martin-Garcia N., Delfau-Larue M., Berger F., Briere J., Macintyre E., Marafioti T. et al., 2011. p. 147 dans 11th International Conference on Malignant Lymphoma, Annals of Oncology. Peer-reviewed.
Tricky and terrible T-cell tumors: these are thrilling times for testing: molecular pathology of peripheral T-cell lymphomas.
de Leval L., Gaulard P., 2011. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program, 2011 pp. 336-343.
Ubiquitin-mediated protein degradation and methylation-induced gene silencing cooperate in the inactivation of the INK4/ARF locus in Burkitt lymphoma cell lines.
Roberti A., Rizzolio F., Lucchetti C., de Leval L., Giordano A., 2011/01/01. Cell cycle, 10 (1) pp. 127-134. Peer-reviewed.
Follicular lymphoma
Harris NL., De Leval L., Ferry JA., 2010/09. pp. 267-290 dans Jaffe ES., Harris NL., Vardiman JW., Campo E., Arber DA. (eds.) Hematopathology: Expert Consult chap. 17, Saunders (W.B.); Elsevier.
Peripheral T-cell lymphoma, Not Otherwise Specified
de Leval L., Ralfkiaer E., Jaffe ES, 2010/09. pp. 541-553 dans Jaffe ES., Harris NL., Vardiman JW., Campo E., Arber DA. (eds.) Hematopathology: Expert Consult chap. 34, Saunders (W.B.); Elsevier.
Advances in the understanding and management of angioimmunoblastic T-cell lymphoma.
de Leval L., Gisselbrecht C., Gaulard P., 2010. British Journal of Haematology, 148 (5) pp. 673-689.
An unusual uterine tumour with signet ring cell features
Rossella S., Fiche M., Achtari C., Ketterer N., de Laval L., 2010. p. 195 dans 22nd European Congress of Pathology, Virchows Archiv. Peer-reviewed.
CD30+ lymphoproliferative disorders.
de Leval L., Gaulard P., 2010. Haematologica, 95 (10) pp. 1627-1630.
Classification moléculaire des lymphomes T ganglionnaires: implications pathologiques et diagnostiques [Molecular classification of ganglionic T cell lymphomas. pathological and diagnostic implications].
de Leval L., 2010. Bulletin et Mémoires De L'académie Royale De Médecine De Belgique, 165 (1-2) p. 99.
Differential expression of NF-kappaB target genes in MALT lymphoma with and without chromosome translocation: insights into molecular mechanism.
Hamoudi R.A., Appert A., Ye H., Ruskone-Fourmestraux A., Streubel B., Chott A., Raderer M., Gong L., Wlodarska I., De Wolf-Peeters C. et al., 2010. Leukemia, 24 (8) pp. 1487-1497.
Diffuse large B-cell lymphomas
de Leval L., Harris NL., 2010. pp. 560-586 dans Margrath IA. (eds.) The lymphoid Neoplasms, Hodder Arnold.
Diverse phenotypic profile of uterine tumors resembling ovarian sex cord tumors: an immunohistochemical study of 12 cases.
de Leval L., Lim G.S., Waltregny D., Oliva E., 2010. American Journal of Surgical Pathology, 34 (12) pp. 1749-1761.
Fatal case of Epstein-Barr virus primo-infection, haemophagocytic syndrome in a 26-year-old patient treated with azathioprine for Crohn's disease: an autopsy case
Smolders S., Rotman S., de Leval L., 2010. p. 158 dans -, Virchows Archiv. Peer-reviewed.
Galectin fingerprinting in Warthin's tumors: lectin-based approach to trace its origin?
Saussez S., de Leval L., Decaestecker C., Sirtaine N., Cludts S., Duray A., Chevalier D., André S., Gabius H.J., Remmelink M. et al., 2010. Histology and Histopathology, 25 (5) pp. 541-550.
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