David Gatfield

Publications | Mémoires et thèses

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34 publications

2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 1999 |
Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock.
Castelo-Szekely V., De Matos M., Tusup M., Pascolo S., Ule J., Gatfield D., 2019/06/04. Nucleic Acids Research, 47 (10) pp. 5193-5209. Peer-reviewed.
 
Design of in vitro Transcribed mRNA Vectors for Research and Therapy.
Tusup M., French L.E., De Matos M., Gatfield D., Kundig T., Pascolo S., 2019/05/29. Chimia, 73 (6) pp. 391-394. Peer-reviewed.
Transcriptome-wide sites of collided ribosomes reveal principles of translational pausing
Arpat Alaaddin Bulak, Liechti Angélica, Matos Mara De, Dreos René, Janich Peggy, Gatfield David, 2019. bioRxiv.
Circadian Clocks and UPR: New Twists as the Story Unfolds.
Milev N.B., Gatfield D., 2018/01/08. Developmental cell, 44 (1) pp. 7-9. Peer-reviewed.
Translational contributions to tissue specificity in rhythmic and constitutive gene expression.
Castelo-Szekely V., Arpat A.B., Janich P., Gatfield D., 2017/06/16. Genome biology, 18 (1) p. 116. Peer-reviewed.
 
Diurnal Oscillations in Liver Mass and Cell Size Accompany Ribosome Assembly Cycles.
Sinturel F., Gerber A., Mauvoisin D., Wang J., Gatfield D., Stubblefield J.J., Green C.B., Gachon F., Schibler U., 2017. Cell, 169 (4) pp. 651-663.e14. Peer-reviewed.
Guidelines for Genome-Scale Analysis of Biological Rhythms.
Hughes M.E., Abruzzi K.C., Allada R., Anafi R., Arpat A.B., Asher G., Baldi P., de Bekker C., Bell-Pedersen D., Blau J. et al., 2017. Journal of Biological Rhythms, 32 (5) pp. 380-393. Peer-reviewed.
Analyzing the temporal regulation of translation efficiency in mouse liver.
Janich P., Arpat A.B., Castelo-Szekely V., Gatfield D., 2016. Genomics Data, 8 pp. 41-44. Peer-reviewed.
 
Translational contributions to tissue-specificity in rhythmic and constitutive gene expression.
Castelo-Szekely V., Arpat A.B., Janich P., Gatfield D., 2016. bioRxiv, 060368 pp. NA.
A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.
Mang G.M., Pradervand S., Du N.H., Arpat A.B., Preitner F., Wigger L., Gatfield D., Franken P., 2015. PLoS One, 10 (1) pp. e0116760.
Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames.
Janich P., Arpat A.B., Castelo-Szekely V., Lopes M., Gatfield D., 2015. Genome Research, 25 (12) pp. 1848-1859. Peer-reviewed.
MicroRNAs shape circadian hepatic gene expression on a transcriptome-wide scale.
Du N.H., Arpat A.B., De Matos M., Gatfield D., 2014. Elife, 3 pp. e02510.
 
Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells.
Bieler J., Cannavo R., Gustafson K., Gobet C., Gatfield D., Naef F., 2014. Molecular Systems Biology, 10 (7) p. 739. Peer-reviewed.
 
CAVIN-3 regulates circadian period length and PER:CRY protein abundance and interactions.
Schneider K., Köcher T., Andersin T., Kurzchalia T., Schibler U., Gatfield D., 2012. EMBO Reports, 13 (12) pp. 1138-1144.
 
Mammalian genes are transcribed with widely different bursting kinetics.
Suter D.M., Molina N., Gatfield D., Schneider K., Schibler U., Naef F., 2011. Science, 332 (6028) pp. 472-474.
MicroRNA-122 modulates the rhythmic expression profile of the circadian deadenylase Nocturnin in mouse liver.
Kojima S., Gatfield D., Esau C.C., Green C.B., 2010. PLoS One, 5 (6) pp. e11264.
 
Integration of microRNA miR-122 in hepatic circadian gene expression.
Gatfield D., Le Martelot G., Vejnar C.E., Gerlach D., Schaad O., Fleury-Olela F., Ruskeepää A.L., Oresic M., Esau C.C., Zdobnov E.M. et al., 2009. Genes and Development, 23 (11) pp. 1313-1326.
 
REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis.
Le Martelot G., Claudel T., Gatfield D., Schaad O., Kornmann B., Sasso G.L., Moschetta A., Schibler U., 2009. PLoS Biology, 7 (9) pp. e1000181.
 
Circadian glucose homeostasis requires compensatory interference between brain and liver clocks.
Gatfield D., Schibler U., 2008. Proceedings of the National Academy of Sciences of the United States of America, 105 (39) pp. 14753-14754.
 
SIRT1 regulates circadian clock gene expression through PER2 deacetylation.
Asher G., Gatfield D., Stratmann M., Reinke H., Dibner C., Kreppel F., Mostoslavsky R., Alt F.W., Schibler U., 2008. Cell, 134 (2) pp. 317-328.
 
A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay.
Behm-Ansmant I., Gatfield D., Rehwinkel J., Hilgers V., Izaurralde E., 2007. EMBO Journal, 26 (6) pp. 1591-1601.
 
Physiology. Proteasomes keep the circadian clock ticking.
Gatfield D., Schibler U., 2007. Science, 316 (5828) pp. 1135-1136.
 
Genome-wide oscillation of transcription in yeast.
Reinke H., Gatfield D., 2006. Trends in Biochemical Sciences, 31 (4) pp. 189-191.
 
A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.
Rehwinkel J., Behm-Ansmant I., Gatfield D., Izaurralde E., 2005. RNA, 11 (11) pp. 1640-1647.
 
An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay.
Palacios I.M., Gatfield D., St Johnston D., Izaurralde E., 2004. Nature, 427 (6976) pp. 753-757.
 
Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila.
Gatfield D., Izaurralde E., 2004. Nature, 429 (6991) pp. 575-578.
 
A novel mode of RBD-protein recognition in the Y14-Mago complex.
Fribourg S., Gatfield D., Izaurralde E., Conti E., 2003. Nature Structural Biology, 10 (6) pp. 433-439.
 
Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways.
Gatfield D., Unterholzner L., Ciccarelli F.D., Bork P., Izaurralde E., 2003. EMBO Journal, 22 (15) pp. 3960-3970.
 
REF1/Aly and the additional exon junction complex proteins are dispensable for nuclear mRNA export.
Gatfield D., Izaurralde E., 2002. Journal of Cell Biology, 159 (4) pp. 579-588.
 
REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus.
Rodrigues J.P., Rode M., Gatfield D., Blencowe B.J., Carmo-Fonseca M., Izaurralde E., 2001. Proceedings of the National Academy of Sciences of the United States of America, 98 (3) pp. 1030-1035.
 
The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila.
Gatfield D., Le Hir H., Schmitt C., Braun I.C., Köcher T., Wilm M., Izaurralde E., 2001. Current Biology, 11 (21) pp. 1716-1721.
 
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
Le Hir H., Gatfield D., Izaurralde E., Moore M.J., 2001. EMBO Journal, 20 (17) pp. 4987-4997.
 
The protein Mago provides a link between splicing and mRNA localization.
Le Hir H., Gatfield D., Braun I.C., Forler D., Izaurralde E., 2001. EMBO Reports, 2 (12) pp. 1119-1124.
 
Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis.
Walker K., Ketchum R.E., Hezari M., Gatfield D., Goleniowski M., Barthol A., Croteau R., 1999. Archives of Biochemistry and Biophysics, 364 (2) pp. 273-279.
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