Gerasimos Sykiotis

Publications | Phd and Masters theses

Advanced search is available through Serval

Publications can be managed by accessing Serval via MyUnil


112 publications

In press | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 | 2007 | 2006 | 2005 | 2003 | 2002 | 2001 |
In press
The impact of electronic versus paper-based data capture on data collection logistics and on missing scores in thyroid cancer patients.
Singer S., Sykiotis G., Al-Ibraheem A., Pinto M., Iakovou I., Østhus A.A., Hammerlid E., Locati L.D., Gamper E.M., Arraras J.I. et al. Endocrine. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C7DA157DB2E0]
2024
 
Increased Pituitary Fluorine-18-Fluorodeoxyglucose Uptake in Patients with Differentiated Thyroid Cancer in Hypothyroidism versus under Recombinant Human Thyroid-Stimulating Hormone Stimulation.
Shi X., Giordani I., Nicod Lalonde M., Sykiotis G.P., 2024/03/31. Cancers, 16 (7). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FDFC65C0CDFF]
Transcriptomic profiling of the response to excess iodide in Keap1 hypomorphic mice reveals new gene-environment interactions in thyroid homeostasis.
Ziros P.G., Chartoumpekis D.V., Georgakopoulos-Soares I., Psarias G., Sykiotis G.P., 2024/02. Redox biology, 69 p. 102978. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CC6F475A89B3]
2023
 
International Phase IV Field Study for the Reliability and Validity of the European Organisation for Research and Treatment of Cancer Thyroid Cancer Module EORTC QLQ-THY34.
Singer S., Al-Ibraheem A., Pinto M., Iakovou I., Østhus A.A., Hammerlid E., Locati L.D., Gamper E., Ignacio J., Jordan S.J. et al., 2023/09. Thyroid, 33 (9) pp. 1078-1089. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9CDF25BDCD9E]
ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice.
Peng Z., Ziros P.G., Martini T., Liao X.H., Stoop R., Refetoff S., Albrecht U., Sykiotis G.P., Kellenberger S., 2023/08/17. Communications biology, 6 (1) p. 857. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B248EF4DD49B]
 
Long-Term Survival Analysis and Prognostic Factors of Arabic Patients with Differentiated Thyroid Carcinoma: A 20-Year Observational Study at the King Hussein Cancer Center (KHCC) Involving 528 Patients.
Al-Ibraheem A., Al-Rasheed U., Mashhadani N., Abdlkadir A.S., Al-Adhami D.A., Ruzzeh S., Istatieh F., Mansour A., Hamdan B., Kheetan R. et al., 2023/08/15. Cancers, 15 (16) p. 4102. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_35BF366742E4]
 
Use of lenvatinib in the treatment of radioiodine-refractory differentiated thyroid cancer: a multidisciplinary perspective for daily practice.
Capdevila J., Deandreis D., Durante C., Leboulleux S., Luster M., Netea-Maier R., Newbold K., Singer S., Sykiotis G.P., Bartes B. et al., 2023/08/08. European thyroid journal, 12 (5). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1AD898F4E364]
 
Parathyroid Imaging.
Lalonde M.N., Correia R.D., Syktiotis G.P., Schaefer N., Matter M., Prior J.O., 2023/07. Seminars in nuclear medicine, 53 (4) pp. 490-502. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CDE769CC5FE9]
Feasibility and Performance of Free-Hand Single-Photon Computed Tomography/Ultrasonography for Preoperative Parathyroid Adenoma Localization: A Pilot Study.
Champendal M., Jreige M., Nicod Lalonde M., Pires Jorge J.A., Matter M., Sykiotis G.P., Prior J.O., 2023/06/28. Diagnostics, 13 (13) p. 2200. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_99A4C7E22AF7]
 
Screening of natural compounds for antioxidant transcriptional activity and effects on the thyroid
Ziros Panos, Psarias Georgios, Chartoumpekis Dionysios, Sykiotis Gerasimos P., 2023/05. Free Radical Biology and Medicine, 201 pp. 35-36.
[DOI][WoS][serval:BIB_0715079035F4]
2022
Autophagy activation can partially rescue proteasome dysfunction-mediated cardiac toxicity.
Papanagnou E.D., Gumeni S., Sklirou A.D., Rafeletou A., Terpos E., Keklikoglou K., Kastritis E., Stamatelopoulos K., Sykiotis G.P., Dimopoulos M.A. et al., 2022/11. Aging cell, 21 (11) pp. e13715. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8203798BCD09]
Emerging roles of Keap1/Nrf2 signaling in the thyroid gland and perspectives for bench-to-bedside translation.
Chartoumpekis D.V., Ziros P.G., Habeos I.G., Sykiotis G.P., 2022/09. Free radical biology & medicine, 190 pp. 276-283. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_415D504588B6]
Thyroid Disorders in Patients Treated with Dimethyl Fumarate for Multiple Sclerosis: A Retrospective Observational Study.
Renaud C.O., Ziros P.G., Mathias A., Pot C., Sykiotis G.P., 2022/05/21. Antioxidants, 11 (5) p. 1015. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_089F1B91EF05]
2021
Dexamethasone Administration in Mice Leads to Less Body Weight Gain over Time, Lower Serum Glucose, and Higher Insulin Levels Independently of NRF2.
Filippopoulou F., Habeos G.I., Rinotas V., Sophocleous A., Sykiotis G.P., Douni E., Chartoumpekis D.V., 2021/12/21. Antioxidants, 11 (1) p. 4. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2BFF57D4A6C3]
CTNNB1 mutations in papillary thyroid carcinoma with prominent myofibroblastic stromal component.
Roukain A., Sykiotis G.P., 2021/11. Modern pathology, 34 (11) pp. 2087-2088. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_914F508BBD04]
Papillary Thyroid Carcinoma with Desmoid-Type Fibromatosis: Review of Published Cases.
Roukain A., La Rosa S., Bongiovanni M., Nicod Lalonde M., Cristina V., Montemurro M., Cochet S., Luquain A., Kopp P.A., Sykiotis G.P., 2021/09/06. Cancers, 13 (17) p. 4482. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E774E4C20ED0]
Keap1/Nrf2 Signaling Pathway.
Sykiotis G.P., 2021/05/22. Antioxidants, 10 (6) p. 828. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EE8112C92E89]
Carcinome anaplasique de la thyroïde : nouvelles approches thérapeutiques [Anaplastic thyroid carcinoma : new therapeutic approaches]
Stamatiou A., Herrera-Gómez R.G., Szturz P., Bisig B., Romano E., Sykiotis G., Gorostidi F., La Rosa S., Kopp P., Cristina V., 2021/05/19. Revue medicale suisse, 17 (739) pp. 962-966. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_E0FB351F6891]
 
Denosumab for the Treatment of Hypercalcemia in a Patient With Parathyroid Carcinoma: A Case Report.
Roukain A., Alwan H., Bongiovanni M., Sykiotis G.P., Kopp P.A., 2021. Frontiers in endocrinology, 12 p. 794988. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4F4E3D5261F5]
Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.
Ziros P.G., Renaud C.O., Chartoumpekis D.V., Bongiovanni M., Habeos I.G., Liao X.H., Refetoff S., Kopp P.A., Brix K., Sykiotis G.P., 2021/01. Thyroid, 31 (1) pp. 23-35. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_62561B304595]
Relapse of Human Chorionic Gonadotropin-Induced Hyperthyroidism and Severe Hyperemesis Gravidarum Secondary to Twin-Twin Transfusion Syndrome, With Rapid Recovery Following Fetoscopic Laser Coagulation: Case Report.
Lamine F., Camponovo C., Baud D., Werner D., Marino L., Sykiotis G.P., 2021. Frontiers in endocrinology, 12 p. 705567. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AC37777241A4]
2020
Patent Review (2017-2020) of the Keap1/Nrf2 Pathway Using PatSeer Pro: Focus on Autoimmune Diseases.
Chartoumpekis D.V., Fu C.Y., Ziros P.G., Sykiotis G.P., 2020/11/17. Antioxidants, 9 (11) pp. E1138. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E93BD1550E44]
The Keap1/Nrf2 Signaling Pathway in the Thyroid-2020 Update.
Thanas C., Ziros P.G., Chartoumpekis D.V., Renaud C.O., Sykiotis G.P., 2020/11/04. Antioxidants, 9 (11) pp. E1082. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F5831CDC48DF]
The Transcriptomic Response of the Murine Thyroid Gland to Iodide Overload and the Role of the Nrf2 Antioxidant System.
Chartoumpekis D.V., Ziros P.G., Georgakopoulos-Soares I., Smith AAT, Marques A.C., Ibberson M., A Kopp P., Habeos I., Trougakos I.P., Khoo NKH et al., 2020/09/18. Antioxidants, 9 (9) pp. E884. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F9FB94E92E22]
The Impact of Levothyroxine on Cardiac Function in Older Adults With Mild Subclinical Hypothyroidism: A Randomized Clinical Trial.
Gencer B., Moutzouri E., Blum M.R., Feller M., Collet T.H., Delgiovane C., da Costa B.R., Buffle E., Monney P., Gabus V. et al., 2020/07. The American journal of medicine, 133 (7) pp. 848-856.e5. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E77F13A45C4A]
A new mouse model of poorly differentiated thyroid carcinoma and its implications for human disease.
Bongiovanni M., Sykiotis G.P., 2020/04. Gland surgery, 9 (2) pp. 481-484. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D567D5C6085F]
Rare and common genetic variations in the Keap1/Nrf2 antioxidant response pathway impact thyroglobulin gene expression and circulating levels, respectively.
Matana A., Ziros P.G., Chartoumpekis D.V., Renaud C.O., Polašek O., Hayward C., Zemunik T., Sykiotis G.P., 2020/03. Biochemical pharmacology, 173 p. 113605. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4E02568FE6AA]
 
Macrofollicular Variant of Follicular Thyroid Carcinoma: A Rare Underappreciated Pitfall in the Diagnosis of Thyroid Carcinoma.
Bongiovanni M., Sykiotis G.P., La Rosa S., Bisig B., Trimech M., Missiaglia E., Gremaud M., Salvatori Chappuis V., De Vito C., Sciarra A. et al., 2020/01. Thyroid, 30 (1) pp. 72-80. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3593CD8A9C4E]
The dietary triterpenoid 18α-Glycyrrhetinic acid protects from MMC-induced genotoxicity through the ERK/Nrf2 pathway.
Lefaki M., Papaevgeniou N., Tur J.A., Vorgias C.E., Sykiotis G.P., Chondrogianni N., 2020/01. Redox biology, 28 p. 101317. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7F64F6BCDA11]
2019
Ablation des nodules thyroïdiens par radiofréquence : alternative à la chirurgie ou traitement de première ligne ? [Radiofrequency ablation of thyroid nodules : an alternative to surgery or first-line treatment ?]
Gueneau De Mussy P., Rouiller N., Denys A., Hocquelet A., Sykiotis G.P., 2019/12/04. Revue medicale suisse, 15 (674) pp. 2257-2261. Peer-reviewed.
[DOI][Pmid][serval:BIB_D93EB0B0D716]
 
Nodules et cancers différenciés de la thyroïde: mise à jour sur le diagnostic et le traitement chirurgical [Thyroid nodules and thyroid differentiated cancers: an update on diagnosis and surgical management.]
De Sandre-Mouly C., Sykiotis G.P., Simon C., Gorostidi F., 2019/10/02. Revue medicale suisse, 15 (665) pp. 1752-1759. Peer-reviewed.
[Pmid][serval:BIB_FB4A7D1FD47F]
A Bibliometric Review of the Keap1/Nrf2 Pathway and its Related Antioxidant Compounds.
Paunkov A., Chartoumpekis D.V., Ziros P.G., Sykiotis G.P., 2019/09/01. Antioxidants, 8 (9). Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_11053F010468]
 
Adverse effects of immune-checkpoint inhibitors: epidemiology, management and surveillance.
Martins F., Sofiya L., Sykiotis G.P., Lamine F., Maillard M., Fraga M., Shabafrouz K., Ribi C., Cairoli A., Guex-Crosier Y. et al., 2019/09. Nature reviews. Clinical oncology, 16 (9) pp. 563-580. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7F8DDEE8DA1E]
Interaction of Genetic Variations in NFE2L2 and SELENOS Modulates the Risk of Hashimoto's Thyroiditis.
Santos L.R., Durães C., Ziros P.G., Pestana A., Esteves C., Neves C., Carvalho D., Bongiovanni M., Renaud C.O., Chartoumpekis D.V. et al., 2019/09. Thyroid, 29 (9) pp. 1302-1315. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D7B155BB39D0]
Approach to cytological indeterminate thyroid nodules.
Bongiovanni M., Bellevicine C., Troncone G., Sykiotis G.P., 2019/08. Gland surgery, 8 (Suppl 2) pp. S98-S104. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3D6CBC1126E8]
 
Expression of Prox1 in Medullary Thyroid Carcinoma Is Associated with Chromogranin A and Calcitonin Expression and with Ki67 Proliferative Index, but Not with Prognosis.
Saglietti C., La Rosa S., Sykiotis G.P., Letovanec I., Bulliard J.L., Piana S., Mermod M., Petrova T., Uccella S., Sessa F. et al., 2019/06. Endocrine pathology, 30 (2) pp. 138-145. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_564B70BCE78F]
Broccoli sprout beverage is safe for thyroid hormonal and autoimmune status: Results of a 12-week randomized trial.
Chartoumpekis D.V., Ziros P.G., Chen J.G., Groopman J.D., Kensler T.W., Sykiotis G.P., 2019/04. Food and chemical toxicology, 126 pp. 1-6. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A1B894228A4D]
Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation.
Tsakiri E.N., Gumeni S., Iliaki K.K., Benaki D., Vougas K., Sykiotis G.P., Gorgoulis V.G., Mikros E., Scorrano L., Trougakos I.P., 2019/02. Aging cell, 18 (1) pp. e12845. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5F0FC273FD9C]
Impact of Antioxidant Natural Compounds on the Thyroid Gland and Implication of the Keap1/Nrf2 Signaling Pathway.
Paunkov A., Chartoumpekis D.V., Ziros P.G., Chondrogianni N., Kensler T.W., Sykiotis G.P., 2019. Current pharmaceutical design, 25 (16) pp. 1828-1846. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E14A050AB1CD]
Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer.
Renaud C.O., Ziros P.G., Chartoumpekis D.V., Bongiovanni M., Sykiotis G.P., 2019. Frontiers in endocrinology, 10 p. 510. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_46BD9E21EAE9]
New therapeutic perspectives to manage refractory immune checkpoint-related toxicities.
Martins F., Sykiotis G.P., Maillard M., Fraga M., Ribi C., Kuntzer T., Michielin O., Peters S., Coukos G., Spertini F. et al., 2019/01. The Lancet. Oncology, 20 (1) pp. e54-e64. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_42DB9145A8A7]
Raman spectroscopy for the preoperative diagnosis of thyroid cancer and its subtypes: An in vitro proof-of-concept study.
O'Dea D., Bongiovanni M., Sykiotis G.P., Ziros P.G., Meade A.D., Lyng F.M., Malkin A., 2019/01. Cytopathology, 30 (1) pp. 51-60. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AC11B3968628]
2018
Endocrine and neuroendocrine cytopathology.
Bongiovanni M., La Rosa S., Sykiotis G.P., 2018/09. Minerva endocrinologica, 43 (3) pp. 294-304. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0F5AD076BFF8]
 
Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial.
Blum M.R., Gencer B., Adam L., Feller M., Collet T.H., da Costa B.R., Moutzouri E., Dopheide J., Depairon M., Sykiotis G.P. et al., 2018/08/01. The Journal of clinical endocrinology and metabolism, 103 (8) pp. 2988-2997. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6597CA6C15DA]
 
NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
Ziros P.G., Habeos I.G., Chartoumpekis D.V., Ntalampyra E., Somm E., Renaud C.O., Bongiovanni M., Trougakos I.P., Yamamoto M., Kensler T.W. et al., 2018/06. Thyroid, 28 (6) pp. 780-798. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3646DC129157]
 
Subclinical hypothyroidism: new trials, old caveats
Lamine Faiza, De Giorgi Sara, Marino Laura, Michalaki Marina, Sykiotis Gerasimos P., 2018/06. Hormones, 17 (2) pp. 231-236.
[DOI][WoS][Pmid][serval:BIB_14D424CF672C]
 
Subclinical hypothyroidism: new trials, old caveats.
Lamine F., De Giorgi S., Marino L., Michalaki M., Sykiotis G.P., 2018/06. Hormones, 17 (2) pp. 231-236. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_368C50B10967]
The Bethesda System for Reporting Thyroid Cytopathology Explained for Practitioners: Frequently Asked Questions.
Bongiovanni M., Papadakis G.E., Rouiller N., Marino L., Lamine F., Bisig B., Ziadi S., Sykiotis G.P., 2018/05. Thyroid, 28 (5) pp. 556-565. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DA68FE57DD84]
 
Congenital hypogonadotropic hypogonadism and constitutional delay of growth and puberty have distinct genetic architectures
Cassatella Daniele, Howard Sasha R, Acierno James S, Xu Cheng, Papadakis Georgios E, Santoni Federico A, Dwyer Andrew A, Santini Sara, Sykiotis Gerasimos P, Chambion Caroline et al., 2018/04. European Journal of Endocrinology, 178 (4) pp. 377-388.
[DOI][WoS][Pmid][serval:BIB_334A063EB536]
Congenital hypogonadotropic hypogonadism and constitutional delay of growth and puberty have distinct genetic architectures.
Cassatella D., Howard S.R., Acierno J.S., Xu C., Papadakis G.E., Santoni F.A., Dwyer A.A., Santini S., Sykiotis G.P., Chambion C. et al., 2018/04. European journal of endocrinology, 178 (4) pp. 377-388. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_92D278111021]
Uptake of 99mTc-MIBI by Sclerosing Pneumocytoma Raising a False Suspicion of Metastasis From Medullary Thyroid Carcinoma.
Papadakis G.E., Tabotta F., Levotanec I., Gonzalez M., Prior J.O., La Rosa S., Sykiotis G.P., 2018/04/01. Journal of the Endocrine Society, 2 (4) pp. 386-390. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_169B42791B55]
 
Hypothyroïdie infraclinique : faut-il encore traiter les personnes âgées ? Implications cliniques d’une nouvelle étude en médecine de famille [Subclinical hypothyroidism : should we still treat elderly patients? Clinical implications of a new trial in primary care]
Collet T.H., Sykiotis G.P., Aubert C.E., Baumgartner C., Blum M.R., Feller M., Stettler C., Rodondi N., 2018/02/28. Revue medicale suisse, 14 (596) pp. 470-474. Peer-reviewed.
[Pmid][serval:BIB_5A30E111F1D9]
Rapid Remission of Graves' Hyperthyroidism Without Thionamides Under Immunosuppressive Treatment for Concomitant Autoimmune Hepatitis.
Papadakis G.E., Lamine F., Chtioui H., Moschouri E., Christinet M.F., Marino L., Favre L., Sciarra A., Sempoux C., Schneider A. et al., 2018/02. Thyroid, 28 (2) pp. 276-278. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9AD89D587A49]
DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development.
Bouilly J., Messina A., Papadakis G., Cassatella D., Xu C., Acierno J.S., Tata B., Sykiotis G., Santini S., Sidis Y. et al., 2018/01/15. Human molecular genetics, 27 (2) pp. 359-372. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E34B12561F91]
2017
FNA diagnosis of poorly differentiated thyroid carcinoma. A review of the recent literature.
Saglietti C., Onenerk A.M., Faquin W.C., Sykiotis G.P., Ziadi S., Bongiovanni M., 2017/12. Cytopathology, 28 (6) pp. 467-474. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AF95D2624BB0]
Nodules et carcinomes thyroïdiens
Rouiller N., Papadakis G., Bongiovanni M, Sykiotis G., 2017/11/22. Swiss Medical Forum = Forum Médical Suisse, 47 pp. 1040-1045. Peer-reviewed.
[URN][serval:BIB_08FC09E15CD8]
KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism.
Xu C., Messina A., Somm E., Miraoui H., Kinnunen T., Acierno J., Niederländer N.J., Bouilly J., Dwyer A.A., Sidis Y. et al., 2017/10. EMBO molecular medicine, 9 (10) pp. 1379-1397. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_569EB14591C9]
 
Genetic testing facilitates prepubertal diagnosis of congenital hypogonadotropic hypogonadism.
Xu C., Lang-Muritano M., Phan-Hug F., Dwyer A.A., Sykiotis G.P., Cassatella D., Acierno J., Mohammadi M., Pitteloud N., 2017/08. Clinical genetics, 92 (2) pp. 213-216. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2FA37B7AE074]
 
Columnar cell variant of papillary thyroid carcinoma: Cytomorphological characteristics of 11 cases with histological correlation and literature review.
Bongiovanni M., Mermod M., Canberk S., Saglietti C., Sykiotis G.P., Pusztaszeri M., Ragazzi M., Mazzucchelli L., Giovanella L., Piana S., 2017/06. Cancer, 125 (6) pp. 389-397. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_56E331DD7F45]
Very low expression of PD-L1 in medullary thyroid carcinoma.
Bongiovanni M., Rebecchini C., Saglietti C., Bulliard J.L., Marino L., de Leval L., Sykiotis G.P., 2017/06. Endocrine-related cancer, 24 (6) pp. L35-L38. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8220EE9B4DFA]
β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.
Somm E., Henry H., Bruce S.J., Aeby S., Rosikiewicz M., Sykiotis G.P., Asrih M., Jornayvaz F.R., Denechaud P.D., Albrecht U. et al., 2017/04/20. JCI insight, 2 (8). Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_94A6C8A6A9EA]
 
Papillary thyroid carcinoma with nodular fasciitis-like stroma and β-catenin mutations should be renamed papillary thyroid carcinoma with desmoid-type fibromatosis.
Rebecchini C., Nobile A., Piana S., Sarro R., Bisig B., Gerasimos S.P., Saglietti C., Matter M., Marino L., Bongiovanni M., 2017/02. Modern pathology, 30 (2) pp. 236-245. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_52ED1FEDAE03]
2016
A Simple Protocol for High Efficiency Protein Isolation After RNA Isolation from Mouse Thyroid and Other Very Small Tissue Samples.
Ziros P.G., Chartoumpekis D.V., Sykiotis G.P., 2016. Methods in molecular biology, 1449 pp. 383-393. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F6CEDB51975B]
Educational Level Is Related to Physical Fitness in Patients with Type 2 Diabetes - A Cross-Sectional Study.
Allet L., Giet O., Barral J., Junod N., Durrer D., Amati F., Sykiotis G.P., Marques-Vidal P., Puder J.J., 2016. PloS one, 11 (10) pp. e0164176. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_5FA95E8ECBEF]
Hepatic Fgf21 Expression Is Repressed after Simvastatin Treatment in Mice.
Ziros P., Zagoriti Z., Lagoumintzis G., Kyriazopoulou V., Iskrenova R.P., Habeos E.I., Sykiotis G.P., Chartoumpekis D.V., Habeos I.G., 2016. Plos One, 11 (9) pp. e0162024. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_940B3CBCD2E3]
Redox Status and Proteostasis in Ageing and Disease.
Rizzi F., Trougakos I.P., Pintus G., Sykiotis G.P., 2016. Oxidative Medicine and Cellular Longevity, 2016 (6) p. 7476241. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0B95BBE49EB5]
2015
Congenital hypogonadotropic hypogonadism with split hand/foot malformation: a clinical entity with a high frequency of FGFR1 mutations.
Villanueva C., Jacobson-Dickman E., Xu C., Manouvrier S., Dwyer A.A., Sykiotis G.P., Beenken A., Liu Y., Tommiska J., Hu Y. et al., 2015/11. Genetics In Medicine : Official Journal of the American College of Medical Genetics, 17 (8) pp. 651-659. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DD27A8DA5823]
2014
Bardoxolone methyl in type 2 diabetes and advanced chronic kidney disease.
Chartoumpekis D.V., Sykiotis G.P., 2014. New England Journal of Medicine, 370 (18) p. 1767.
[URN][WoS][Pmid][serval:BIB_3EE4B1733A5A]
 
Comment tes médecins de famille prennent-ils en charge l'hypothyroïdie infraclinique [How do Swiss family physicians treat subclinical hypothyroidism?].
Virgini V., Baumgartner C., Bischoff T., Haller D.M., Frey P., Rosemann T., Collet T.H., Sykiotis G., Pitteloud N., Rodondi N., 2014. Revue Médicale Suisse, 10 (420) pp. 526-529.
[Pmid][serval:BIB_C0959DB386AC]
2013
 
Hypothyroïdie infraclinique
Blum Manuel R, Collet Tinh-Hai, Krebs Danielle, Stettler Christoph, Christ Emanuel, Virgini Vanessa, Sykiotis Gerasimos, Frey Peter, Reichenbach Stephan, Boulat Olivier et al., 2013/09/23. Forum Medical Suisse, 13 (39) pp. 772-775.
[serval:BIB_74F270F5C15E]
 
Subklinische Hypothyreose: Risiken, aktuelle Empfehlungen und randomisierte Studie in der Swchweiz
Blum Manuel R., Collet Tinh-Hai, Krebs Danielle, Stettler Christoph, Christ Emanuel, Virgini Vanessa, Sykiotis Gerasimos, Frey Peter, Reichenbach Stephan, Boulat Olivier et al., 2013/09/23. Forum Medical Suisse, 13 (39) pp. 772-775.
[serval:BIB_35F5DC1450F0]
 
Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes.
Rahman M.M., Sykiotis G.P., Nishimura M., Bodmer R., Bohmann D., 2013. Aging Cell, 12 (4) pp. 554-562. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C999E3142022]
 
Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress.
Tsakiri E.N., Sykiotis G.P., Papassideri I.S., Gorgoulis V.G., Bohmann D., Trougakos I.P., 2013. Faseb Journal, 27 (6) pp. 2407-2420. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_06B172AB54FF]
 
Hepatic gene expression profiling in Nrf2 knockout mice after long-term high-fat diet-induced obesity.
Chartoumpekis D.V., Ziros P.G., Zaravinos A., Iskrenova R.P., Psyrogiannis A.I., Kyriazopoulou V.E., Sykiotis G.P., Habeos I.G., 2013. Oxidative Medicine and Cellular Longevity, 2013 p. 340731. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C12D65A41242]
 
Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism.
Miraoui H., Dwyer A.A., Sykiotis G.P., Plummer L., Chung W., Feng B., Beenken A., Clarke J., Pers T.H., Dworzynski P. et al., 2013. American Journal of Human Genetics, 92 (5) pp. 725-743.
[DOI][WoS][Pmid][serval:BIB_87AB28BA52A9]
 
Nrf2 is commonly activated in papillary thyroid carcinoma, and it controls antioxidant transcriptional responses and viability of cancer cells.
Ziros P.G., Manolakou S.D., Habeos I.G., Lilis I., Chartoumpekis D.V., Koika V., Soares P., Kyriazopoulou V.E., Scopa C.D., Papachristou D.J. et al., 2013. Journal of Clinical Endocrinology and Metabolism, 98 (8) pp. E1422-E1427. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_93C277B91627]
 
Proteasome dysfunction in Drosophila signals to an Nrf2-dependent regulatory circuit aiming to restore proteostasis and prevent premature aging.
Tsakiri E.N., Sykiotis G.P., Papassideri I.S., Terpos E., Dimopoulos M.A., Gorgoulis V.G., Bohmann D., Trougakos I.P., 2013. Aging Cell, 12 (5) pp. 802-813. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D32E31731F3B]
 
Trial of recombinant follicle-stimulating hormone pretreatment for gnrh-induced fertility in patients with congenital hypogonadotropic hypogonadism.
Dwyer A.A., Sykiotis G.P., Hayes F.J., Boepple P.A., Lee H., Loughlin K.R., Dym M., Sluss P.M., Crowley W.F., Pitteloud N., 2013. Journal of Clinical Endocrinology and Metabolism, 98 (11) pp. E1790-E1795.
[DOI][WoS][Pmid][serval:BIB_3F74C818D23D]
2012
An ancient founder mutation in PROKR2 impairs human reproduction.
Avbelj Stefanija M., Jeanpierre M., Sykiotis G.P., Young J., Quinton R., Abreu A.P., Plummer L., Au M.G., Balasubramanian R., Dwyer A.A. et al., 2012. Human Molecular Genetics, 21 (19) pp. 4314-4324.
[URN][DOI][WoS][Pmid][serval:BIB_6D77B428DE1B]
 
Genetic overlap in kallmann syndrome, combined pituitary hormone deficiency, and septo-optic dysplasia.
Raivio T., Avbelj M., McCabe M.J., Romero C.J., Dwyer A.A., Tommiska J., Sykiotis G.P., Gregory L.C., Diaczok D., Tziaferi V. et al., 2012. Journal of Clinical Endocrinology and Metabolism, 97 (4) pp. E694-E699.
[DOI][WoS][Pmid][serval:BIB_39585636106C]
2011
A genetic basis for functional hypothalamic amenorrhea.
Caronia L.M., Martin C., Welt C.K., Sykiotis G.P., Quinton R., Thambundit A., Avbelj M., Dhruvakumar S., Plummer L., Hughes V.A. et al., 2011. New England Journal of Medicine, 364 (3) pp. 215-225. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C988869DDA2B]
 
Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.
Barone M.C., Sykiotis G.P., Bohmann D., 2011. Disease Models and Mechanisms, 4 (5) pp. 701-707. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F8877F11664B]
 
Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism.
Tornberg J., Sykiotis G.P., Keefe K., Plummer L., Hoang X., Hall J.E., Quinton R., Seminara S.B., Hughes V., Van Vliet G. et al., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (28) pp. 11524-11529.
[DOI][WoS][Pmid][serval:BIB_19FB89539771]
 
Nrf2 activation diminishes during adipocyte differentiation of ST2 cells.
Chartoumpekis D.V., Ziros P.G., Sykiotis G.P., Zaravinos A., Psyrogiannis A.I., Kyriazopoulou V.E., Spandidos D.A., Habeos I.G., 2011. International Journal of Molecular Medicine, 28 (5) pp. 823-828.
[DOI][WoS][Pmid][serval:BIB_968ED398C455]
 
Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in mice.
Chartoumpekis D.V., Ziros P.G., Psyrogiannis A.I., Papavassiliou A.G., Kyriazopoulou V.E., Sykiotis G.P., Habeos I.G., 2011. Diabetes, 60 (10) pp. 2465-2473. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BCF8EA8299B9]
 
The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation.
Sykiotis G.P., Habeos I.G., Samuelson A.V., Bohmann D., 2011. Current Opinion in Clinical Nutrition and Metabolic Care, 14 (1) pp. 41-48. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_884D2CA5B4C3]
2010
 
Complex genetics in idiopathic hypogonadotropic hypogonadism.
Pitteloud N., Durrani S., Raivio T., Sykiotis G.P., 2010. Frontiers of Hormone Research, 39 pp. 142-153. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4A5BC9998C07]
 
Congenital idiopathic hypogonadotropic hypogonadism: evidence of defects in the hypothalamus, pituitary, and testes.
Sykiotis G.P., Hoang X.H., Avbelj M., Hayes F.J., Thambundit A., Dwyer A., Au M., Plummer L., Crowley W.F., Pitteloud N., 2010. Journal of Clinical Endocrinology and Metabolism, 95 (6) pp. 3019-3027. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_27ECD2A886CE]
 
Deciphering genetic disease in the genomic era: the model of GnRH deficiency.
Sykiotis G.P., Pitteloud N., Seminara S.B., Kaiser U.B., Crowley W.F., 2010. Science Translational Medicine, 2 (32) pp. 32rv2. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B55BBC53A8DE]
 
Oligogenic basis of isolated gonadotropin-releasing hormone deficiency.
Sykiotis G.P., Plummer L., Hughes V.A., Au M., Durrani S., Nayak-Young S., Dwyer A.A., Quinton R., Hall J.E., Gusella J.F. et al., 2010. Proceedings of the National Academy of Sciences of the United States of America, 107 (34) pp. 15140-15144. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A51229A4D12D]
 
Stress-activated cap'n'collar transcription factors in aging and human disease.
Sykiotis G.P., Bohmann D., 2010. Science Signaling, 3 (112) pp. re3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_37D4490BF821]
2008
 
Keap1/Nrf2 signaling regulates oxidative stress tolerance and lifespan in Drosophila.
Sykiotis G.P., Bohmann D., 2008. Developmental Cell, 14 (1) pp. 76-85. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_020206E49E0C]
2007
 
Targeting the nerve growth factor network in Alzheimer's disease.
Sykiotis G.P., Papavassiliou A.G., 2007/03. Expert opinion on investigational drugs, 16 (3) pp. 267-269. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4AD36DA7A41D]
2006
 
Apoptosis: the suicide solution in cancer treatment and chemoprevention.
Sykiotis G.P., Papavassiliou A.G., 2006. Expert Opinion on Investigational Drugs, 15 (6) pp. 575-577. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_07B47108665E]
 
Hippocrates and genomic medicine.
Sykiotis G.P., Kalliolias G.D., Papavassiliou A.G., 2006. Archives of Medical Research, 37 (1) pp. 181-183.
[DOI][WoS][Pmid][serval:BIB_93B365716ACD]
 
Molecular Medicine and biomedical education: reshaping our mission.
Sykiotis G.P., Konstantinopoulos P.A., Papavassiliou A.G., 2006. Hormones, 5 (2) pp. 87-89. Peer-reviewed.
[Pmid][serval:BIB_2405396F242D]
2005
 
Erythropoietin abuse and erythropoietin gene doping: detection strategies in the genomic era.
Diamanti-Kandarakis E., Konstantinopoulos P.A., Papailiou J., Kandarakis S.A., Andreopoulos A., Sykiotis G.P., 2005. Sports Medicine, 35 (10) pp. 831-840.
[WoS][Pmid][serval:BIB_BDA9CB8F03F9]
 
Molecular medicine: a lifetime of learning, teaching and caring.
Sykiotis G.P., Papavassiliou A.G., 2005. Trends In Molecular Medicine, 11 (11) pp. 484-485.
[DOI][WoS][Pmid][serval:BIB_3DCA5AB4F846]
 
Of temples and plane trees: the Hippocratic legacy as collective memory.
Sykiotis G.P., Kalliolias G.D., Terezis C., Papavassiliou A.G., 2005. Hormones, 4 (1) pp. 55-58. Peer-reviewed.
[Pmid][serval:BIB_78E0A7E02B2C]
 
Pharmacogenetic principles in the Hippocratic writings.
Sykiotis G.P., Kalliolias G.D., Papavassiliou A.G., 2005. Journal of Clinical Pharmacology, 45 (11) pp. 1218-1220. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_95C3888E7382]
2003
 
Activation of the JNK-AP-1 signal transduction pathway is associated with pathogenesis and progression of human osteosarcomas.
Papachristou D.J., Batistatou A., Sykiotis G.P., Varakis I., Papavassiliou A.G., 2003. Bone, 32 (4) pp. 364-371. Peer-reviewed.
[WoS][Pmid][serval:BIB_BE64A7D51471]
 
Autonomously functioning thyroid nodules in a former iodine-deficient area commonly harbor gain-of-function mutations in the thyrotropin signaling pathway.
Georgopoulos N.A., Sykiotis G.P., Sgourou A., Papachatzopoulou A., Markou K.B., Kyriazopoulou V., Papavassiliou A.G., Vagenakis A.G., 2003. European Journal of Endocrinology / European Federation of Endocrine Societies, 149 (4) pp. 287-292. Peer-reviewed.
[WoS][Pmid][serval:BIB_34CFD6A20C0D]
 
Functional significance of the thyrotropin receptor germline polymorphism D727E.
Sykiotis G.P., Neumann S., Georgopoulos N.A., Sgourou A., Papachatzopoulou A., Markou K.B., Kyriazopoulou V., Paschke R., Vagenakis A.G., Papavassiliou A.G., 2003. Biochemical and Biophysical Research Communications, 301 (4) pp. 1051-1056. Peer-reviewed.
[WoS][Pmid][serval:BIB_B5B0784A1CFA]
 
Oestrogen receptor beta (ERbeta) is abundantly expressed in normal colonic mucosa, but declines in colon adenocarcinoma paralleling the tumour's dedifferentiation.
Konstantinopoulos P.A., Kominea A., Vandoros G., Sykiotis G.P., Andricopoulos P., Varakis I., Sotiropoulou-Bonikou G., Papavassiliou A.G., 2003. European Journal of Cancer, 39 (9) pp. 1251-1258. Peer-reviewed.
[WoS][Pmid][serval:BIB_22B6FF24735B]
 
Selective modulation of postmenopausal women: cutting the Gordian knot of hormone replacement therapy with breast carcinoma.
Diamanti-Kandarakis E., Sykiotis G.P., Papavassiliou A.G., 2003. Cancer, 97 (1) pp. 12-20. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8D142110C075]
 
The alpha2B adrenergic receptor deletion/insertion polymorphism in morbid obesity.
Sykiotis G.P., Polyzogopoulou E., Georgopoulos N.A., Trakada G., Spyropoulos K., Kalfarentzos F., Papavassiliou A.G., Vagenakis A.G., Flordellis C.S., 2003. Clinical Autonomic Research, 13 (3) pp. 203-207. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EB402400FA5C]
2002
 
A somatic mutation in the thyrotropin receptor gene in a patient with an autonomous nodule within a multinodular goiter.
Sykiotis G.P., Sgourou A., Papachatzopoulou A., Markou K.B., Kyriazopoulou V., Papavassiliou A.G., Vagenakis A.G., Georgopoulos N.A., 2002. Hormones, 1 (1) pp. 42-46. Peer-reviewed.
[Pmid][serval:BIB_E37CB03EEF7C]
 
Clinical experience with Norplant subdermal implant system as long-term contraception during adolescence.
Cardamakis E., Georgopoulos A., Fotopoulos A., Sykiotis G.P., Pappas A.P., Lazaris D., Tzingounis V.A., 2002. European Journal of Contraception and Reproductive Health Care, 7 (1) pp. 36-40. Peer-reviewed.
[WoS][Pmid][serval:BIB_3CF3E9F08AEC]
 
Molecular mechanisms of transcriptional regulation by nuclear receptors. Perspectives for therapeutic implications.
Sykiotis G.P., Papavassiliou A.G., 2002. Hormones, 1 (2) pp. 69-75. Peer-reviewed.
[Pmid][serval:BIB_A1A1B594BDBB]
2001
 
Clinical experience with levonorgestrel subdermal implants (Norplant((R)))(1) for long-term contraception.
Cardamakis Emanuel, Georgopoulos Neoklis A., Pappas Athanassios P., Fotopoulos Andreas, Sykiotis Gerasimos P., Tzingounis Vassilios A., 2001. Clinical Drug Investigation, 21 (12) pp. 827-834.
[DOI][WoS][serval:BIB_19B2920434BD]
 
Ovulation induction with pulsatile gonadotropin-releasing hormone (GnRH) or gonadotropins in a case of hypothalamic amenorrhea and diabetes insipidus.
Georgopoulos N.A., Markou K.B., Pappas A.P., Protonatariou A., Vagenakis G.A., Sykiotis G.P., Dimopoulos P.A., Tzingounis V.A., 2001. Gynecological Endocrinology, 15 (6) pp. 421-425. Peer-reviewed.
[WoS][Pmid][serval:BIB_0967B1A62ABD]
 
Serine phosphorylation of insulin receptor substrate-1: a novel target for the reversal of insulin resistance.
Sykiotis G.P., Papavassiliou A.G., 2001. Molecular Endocrinology, 15 (11) pp. 1864-1869. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FFBEB080826F]
Partagez:
Unicentre - CH-1015 Lausanne
Suisse
Tél. +41 21 692 11 11
Canton de Vaud
Swiss University