Christine Sempoux

Publications | Mémoires et thèses

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349 publications

... | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1990 |
 
Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Nyiraneza C., Jouret-Mourin A., Kartheuser A., Camby P., Plomteux O., Detry R., Dahan K., Sempoux C., 2011. Human Pathology, 42 (12) pp. 1897-1910. Peer-reviewed.
 
EGF61 polymorphism predicts complete pathologic response to cetuximab-based chemoradiation independent of KRAS status in locally advanced rectal cancer patients.
Hu-Lieskovan S., Vallbohmer D., Zhang W., Yang D., Pohl A., Labonte M.J., Grimminger P.P., Hölscher A.H., Semrau R., Arnold D. et al., 2011. Clinical Cancer Research, 17 (15) pp. 5161-5169. Peer-reviewed.
 
Familial adenomatous polyposis: clinical presentation, detection and surveillance.
Laurent S., Franchimont D., Coppens J.P., Leunen K., Macken L., Peeters M., Plomteux O., Polus M., Poppe B., Sempoux C. et al., 2011. Acta Gastro-enterologica Belgica, 74 (3) pp. 415-420. Peer-reviewed.
 
In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.
Henquin J.C., Nenquin M., Sempoux C., Guiot Y., Bellanné-Chantelot C., Otonkoski T., de Lonlay P., Nihoul-Fékété C., Rahier J., 2011. Journal of Clinical Investigation, 121 (10) pp. 3932-3942. Peer-reviewed.
 
Intrahepatic cholangiocarcinoma: new insights in pathology.
Sempoux C., Jibara G., Ward S.C., Fan C., Qin L., Roayaie S., Fiel M.I., Schwartz M., Thung S.N., 2011. Seminars in Liver Disease, 31 (1) pp. 49-60. Peer-reviewed.
 
Morphologic analysis of focal and diffuse forms of congenital hyperinsulinism.
Rahier J., Guiot Y., Sempoux C., 2011. Seminars in Pediatric Surgery, 20 (1) pp. 3-12.
 
Morphological mosaicism of the pancreatic islets: a novel anatomopathological form of persistent hyperinsulinemic hypoglycemia of infancy.
Sempoux C., Capito C., Bellanné-Chantelot C., Verkarre V., de Lonlay P., Aigrain Y., Fekete C., Guiot Y., Rahier J., 2011. Journal of Clinical Endocrinology and Metabolism, 96 (12) pp. 3785-3793. Peer-reviewed.
 
ABCC8 and KCNJ11 molecular spectrum of 109 patients with diazoxide-unresponsive congenital hyperinsulinism.
Bellanné-Chantelot C., Saint-Martin C., Ribeiro M.J., Vaury C., Verkarre V., Arnoux J.B., Valayannopoulos V., Gobrecht S., Sempoux C., Rahier J. et al., 2010. Journal of Medical Genetics, 47 (11) pp. 752-759. Peer-reviewed.
 
Accurate KRAS mutation testing for EGFR-targeted therapy in colorectal cancer: emphasis on the key role and responsibility of pathologists.
Hoorens A., Jouret-Mourin A., Sempoux C., Demetter P., De Hertogh G., Teugels E., 2010. Acta Gastro-enterologica Belgica, 73 (4) pp. 497-503. Peer-reviewed.
 
Congenital hyperinsulinism.
Arnoux J.B., de Lonlay P., Ribeiro M.J., Hussain K., Blankenstein O., Mohnike K., Valayannopoulos V., Robert J.J., Rahier J., Sempoux C. et al., 2010. Early Human Development, 86 (5) pp. 287-294. Peer-reviewed.
 
Conservative and operative management of benign solid hepatic tumours: a successful stratified algorithm.
Dardenne S., Hubert C., Sempoux C., Annet L., Jouret-Mourin A., Horsmans Y., Van Beers B.E., Zech F., Gigot J.F., 2010. European Journal of Gastroenterology and Hepatology, 22 (11) pp. 1337-1344. Peer-reviewed.
 
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats.
Borbath I., Leclercq I.A., Sempoux C., Abarca-Quinones J., Desaeger C., Horsmans Y., 2010. Chemico-biological Interactions, 183 (1) pp. 238-248. Peer-reviewed.
 
Endoplasmic reticulum accumulation of Kir6.2 without activation of ER stress response in islet cells from adult Sur1 knockout mice.
Marhfour I., Jonas J.C., Marchandise J., Lefevre A., Rahier J., Sempoux C., Guiot Y., 2010. Cell and Tissue Research, 340 (2) pp. 335-346. Peer-reviewed.
 
Endoscopic mucosal or submucosal resection of early neoplasia in Barrett's esophagus after antireflux surgery.
Van Den Eynde M., Jouret-Mourin A., Sempoux C., Piessevaux H., Deprez P.H., 2010. Gastrointestinal Endoscopy, 72 (4) pp. 855-861. Peer-reviewed.
 
Factors predicting the quality of total mesorectal excision for rectal cancer.
Leonard D., Penninckx F., Fieuws S., Jouret-Mourin A., Sempoux C., Jehaes C., Van Eycken E., PROCARE a multidisciplinary Belgian Project on Cancer of the Rectum, 2010. Annals of Surgery, 252 (6) pp. 982-988. Peer-reviewed.
 
High risk for neoplastic transformation of endometriosis in a carrier of Lynch syndrome.
Nyiraneza C., Marbaix E., Smets M., Galant C., Sempoux C., Dahan K., 2010. Familial Cancer, 9 (3) pp. 383-387. Peer-reviewed.
 
Large spectrum of liver vascular lesions including high prevalence of focal nodular hyperplasia in patients with hereditary haemorrhagic telangiectasia: the Belgian Registry based on 30 patients.
Brenard R., Chapaux X., Deltenre P., Henrion J., De Maeght S., Horsmans Y., Borbath I., Leenaerts A., Van Cauter J., Francque S. et al., 2010. European Journal of Gastroenterology and Hepatology, 22 (10) pp. 1253-1259.
 
Liver transplantation and neuroendocrine tumors: lessons from a single centre experience and from the literature review.
Bonaccorsi-Riani E., Apestegui C., Jouret-Mourin A., Sempoux C., Goffette P., Ciccarelli O., Borbath I., Hubert C., Gigot J.F., Hassoun Z. et al., 2010. Transplant International, 23 (7) pp. 668-678. Peer-reviewed.
 
MRI of iron-oxide labelled transplanted hepatocytes in mice: effect of treatment with cyclophosphamide.
Leconte I., Pallu S., Abarca-Quinones J., Michoux N., Peeters F., Radermacher K., Sempoux C., Najimi M., Sokal E., Van Beers B.E., 2010. Journal of Magnetic Resonance Imaging, 32 (2) pp. 367-375. Peer-reviewed.
 
Prevalence and clinical relevance of pathological hepatic changes occurring after neoadjuvant chemotherapy for colorectal liver metastases.
Hubert C., Fervaille C., Sempoux C., Horsmans Y., Humblet Y., Machiels J.P., Zech F., Ceratti A., Gigot J.F., 2010. Surgery, 147 (2) pp. 185-194. Peer-reviewed.
 
Successful long-term management of a patient with late-stage metastatic colorectal cancer treated with panitumumab.
Seront E., Marot L., Coche E., Gala J.L., Sempoux C., Humblet Y., 2010. Cancer Treatment Reviews, 36 (Suppl 1) pp. S11-S14. Peer-reviewed.
 
Vascular reconstruction during pancreatoduodenectomy for ductal adenocarcinoma of the pancreas improves resectability but does not achieve cure.
Ouaissi M., Hubert C., Verhelst R., Astarci P., Sempoux C., Jouret-Mourin A., Loundou A., Gigot J.F., Multidisciplary HPB Group of Center of Cancer, 2010. World Journal of Surgery, 34 (11) pp. 2648-2661. Peer-reviewed.
 
A kernel-based integration of genome-wide data for clinical decision support.
Daemen A., Gevaert O., Ojeda F., Debucquoy A., Suykens J.A., Sempoux C., Machiels J.P., Haustermans K., De Moor B., 2009. Genome Medicine, 1 (4) p. 39. Peer-reviewed.
 
Autoimmune pancreatitis, sclerosing cholangitis, liver inflammatory pseudotumors, retroperitoneal fibrosis, lymphadenopathy, and sialoadenitis in a single patient: a multifaceted expression of a hitherto unrecognized systemic autoimmune syndrome?
de Suray N., Van Beers B., Sempoux C., Borschette C., Lonneux M., Deprez P., Geubel A., 2009. Pancreas, 38 (4) pp. 476-478.
 
CT underestimation of ileo-colic ischemia: a case report with pathologic correlation.
Thiery C., Sempoux C., Danse E., 2009. Jbr-btr : Organe de la Société Royale Belge de Radiologie (srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (kbvr), 92 (4) pp. 213-217. Peer-reviewed.
 
Impact of Sur1 gene inactivation on the morphology of mouse pancreatic endocrine tissue.
Marhfour I., Moulin P., Marchandise J., Rahier J., Sempoux C., Guiot Y., 2009. Cell and Tissue Research, 335 (3) pp. 505-515.
 
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer.
Debucquoy A., Haustermans K., Daemen A., Aydin S., Libbrecht L., Gevaert O., De Moor B., Tejpar S., McBride W.H., Penninckx F. et al., 2009. Journal of Clinical Oncology, 27 (17) pp. 2751-2757. Peer-reviewed.
 
Rare presentation of familial paraganglioma without evidence of mutation in the SDH, RET and VHL genes: towards further genetic heterogeneity.
Persu A., Amyere M., Gutierrez-Roelens I., Rustin P., Sempoux C., Lecouvet F.E., Van Beers B.E., Horsmans Y., De Plaen J.F., MarcHamoir M. et al., 2009. Journal of Hypertension, 27 (1) pp. 76-82. Peer-reviewed.
 
Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
Van Hul N.K., Abarca-Quinones J., Sempoux C., Horsmans Y., Leclercq I.A., 2009. Hepatology, 49 (5) pp. 1625-1635. Peer-reviewed.
 
Ulcerative colitis associated with IgG4 cholangitis: similar features in two HLA identical siblings.
Dastis S.N., Latinne D., Sempoux C., Geubel A.P., 2009. Journal of Hepatology, 51 (3) pp. 601-605. Peer-reviewed.
 
Une mastocytose inhabituelle.. [An unusual mastocytosis...].
Bafort D., Sempoux C., Bohon P., Theate I., Jouret-Mourin A., 2009. Annales de Pathologie, 29 (5) pp. 440-442. Peer-reviewed.
 
Une tumeur duodénale inhabituelle [An uncommon duodenal tumor].
Ho Minh Duc D.K., Sempoux C., Theate I., Collard J.M., Jouret-Mourin A., 2009. Annales de Pathologie, 29 (5) pp. 432-434.
 
Usefulness of histopathological markers in diagnosing Barrett's intraepithelial neoplasia (dysplasia).
Jouret-Mourin A., Sempoux C., Duc K.H., Geboes K., 2009. Acta Gastro-enterologica Belgica, 72 (4) pp. 425-432. Peer-reviewed.
 
Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. John's wort). Case of drug interaction?
Etogo-Asse F., Boemer F., Sempoux C., Geubel A., 2008. Acta Gastro-enterologica Belgica, 71 (1) pp. 36-38. Peer-reviewed.
 
Magnetic resonance elastography for the noninvasive staging of liver fibrosis.
Huwart L., Sempoux C., Vicaut E., Salameh N., Annet L., Danse E., Peeters F., ter Beek L.C., Rahier J., Sinkus R. et al., 2008. Gastroenterology, 135 (1) pp. 32-40. Peer-reviewed.
 
Pancreatic beta-cell mass in European subjects with type 2 diabetes.
Rahier J., Guiot Y., Goebbels R.M., Sempoux C., Henquin J.C., 2008. Diabetes, Obesity and Metabolism, 10 (Suppl 4) pp. 32-42. Peer-reviewed.
 
Stepwise radical endoscopic resection for Barrett's esophagus with early neoplasia: report on a Brussels' cohort.
Pouw R.E., Peters F.P., Sempoux C., Piessevaux H., Deprez P.H., 2008. Endoscopy, 40 (11) pp. 892-898. Peer-reviewed.
 
Tacrolimus monotherapy in liver transplantation: one-year results of a prospective, randomized, double-blind, placebo-controlled study.
Lerut J., Mathys J., Verbaandert C., Talpe S., Ciccarelli O., Lemaire J., Bonaccorsi-Riani E., Vanthuyne V., Hetsch N., Roggen F. et al., 2008. Annals of Surgery, 248 (6) pp. 956-967.
Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes?
Najimi M., Khuu D.N., Lysy P.A., Jazouli N., Abarca J., Sempoux C., Sokal E.M., 2007. Cell Transplantation, 16 (7) pp. 717-728. Peer-reviewed.
 
Benign biliary inflammatory pseudotumor mimicking a Klatskin tumor.
Gohy S., Hubert C., Deprez P., Van Beers B.E., Annet L., Lhommel R., Sempoux C., Jean-François G., 2007. Hepato-gastroenterology, 54 (77) pp. 1348-1352. Peer-reviewed.
 
Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide.
Borbath I., Leclercq I.A., Abarca-Quinones J., Desaeger C., Lebrun V., Moulin P., Sempoux C., Horsmans Y., 2007. Cancer Science, 98 (12) pp. 1831-1839. Peer-reviewed.
 
Liver fibrosis: noninvasive assessment with MR elastography versus aspartate aminotransferase-to-platelet ratio index.
Huwart L., Sempoux C., Salameh N., Jamart J., Annet L., Sinkus R., Peeters F., ter Beek L.C., Horsmans Y., Van Beers B.E., 2007. Radiology, 245 (2) pp. 458-466. Peer-reviewed.
 
Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas.
Guiot Y., Stevens M., Marhfour I., Stiernet P., Mikhailov M., Ashcroft S.J., Rahier J., Henquin J.C., Sempoux C., 2007. Diabetologia, 50 (9) pp. 1889-1899. Peer-reviewed.
 
Nodular regenerative hyperplasia: a deleterious consequence of chemotherapy for colorectal liver metastases?
Hubert C., Sempoux C., Horsmans Y., Rahier J., Humblet Y., Machiels J.P., Ceratti A., Canon J.L., Gigot J.F., 2007. Liver International : Official Journal of the International Association For the Study of the Liver, 27 (7) pp. 938-943. Peer-reviewed.
 
Percutaneous and surgical radiofrequency ablation of liver malignancies: a single institutional experience.
Hubert C., Gras J., Goffette P., Grajeda J.M., Van Beers B.E., Laurence A., Horsmans Y., Sempoux C., Rahier J., Zech F. et al., 2007. Acta Gastro-enterologica Belgica, 70 (2) pp. 188-194. Peer-reviewed.
 
Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer.
Machiels J.P., Sempoux C., Scalliet P., Coche J.C., Humblet Y., Van Cutsem E., Kerger J., Canon J.L., Peeters M., Aydin S. et al., 2007. Annals of Oncology : Official Journal of the European Society For Medical Oncology, 18 (4) pp. 738-744. Peer-reviewed.
 
Prognostic risk factors of survival after resection of hepatocellular carcinoma.
Hubert C., Sempoux C., Rahier J., Horsmans Y., Geubel A., Van Beers B.E., Annet L., Zech F., Leonard D., Gigot J.F., 2007. Hepato-gastroenterology, 54 (78) pp. 1791-1797. Peer-reviewed.
 
The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver.
Borbath I., Leclercq I., Moulin P., Sempoux C., Horsmans Y., 2007. European Journal of Cancer (oxford, England : 1990), 43 (11) pp. 1755-1763. Peer-reviewed.
 
Hepatogastroenterologist and pathologist: a winning team ... for good patient management
Jouret Anne, Geubel A. P., Sempoux Christine, 2006/06. Acta Endoscopica, 36 (3) pp. I-III.
 
Non-alcoholic fatty liver disease: from steatosis to cirrhosis. [Hépatopathie non alcoolique: de la stéatose à la cirrhose]
Leclercq I., Sempoux C., 2006/06. Acta Endoscopica, 36 (3) pp. 299-314. Peer-reviewed.
 
Congenital hyperinsulinism and mosaic abnormalities of the ploidy.
Giurgea I., Sanlaville D., Fournet J.C., Sempoux C., Bellanné-Chantelot C., Touati G., Hubert L., Groos M.S., Brunelle F., Rahier J. et al., 2006. Journal of Medical Genetics, 43 (3) pp. 248-254. Peer-reviewed.
 
Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin.
Leclercq I.A., Vansteenberghe M., Lebrun V.B., VanHul N.K., Abarca-Quinones J., Sempoux C.L., Picard C., Stärkel P., Horsmans Y.L., 2006. Laboratory Investigation; A Journal of Technical Methods and Pathology, 86 (11) pp. 1161-1171. Peer-reviewed.
 
Hypervitaminosis A-induced liver fibrosis: stellate cell activation and daily dose consumption.
Nollevaux M.C., Guiot Y., Horsmans Y., Leclercq I., Rahier J., Geubel A.P., Sempoux C., 2006. Liver International : Official Journal of the International Association For the Study of the Liver, 26 (2) pp. 182-186. Peer-reviewed.
 
Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats.
Leclercq I.A., Sempoux C., Stärkel P., Horsmans Y., 2006. Gut, 55 (7) pp. 1020-1029. Peer-reviewed.
 
Long-term survival after isolated liver transplantation for intrahepatic biliary papillomatosis.
Charre L., Boillot O., Goffette P., Geubel A., Gigot J.F., Sempoux C., Lerut J., 2006. Transplant International : Official Journal of the European Society For Organ Transplantation, 19 (3) pp. 249-252. Peer-reviewed.
 
Molecular mechanisms of neonatal hyperinsulinism.
Giurgea I., Bellanné-Chantelot C., Ribeiro M., Hubert L., Sempoux C., Robert J.J., Blankenstein O., Hussain K., Brunelle F., Nihoul-Fékété C. et al., 2006. Hormone Research, 66 (6) pp. 289-296. Peer-reviewed.
 
Propylthiouracyl-induced severe liver toxicity: an indication for alanine aminotransferase monitoring?
Benyounes M., Sempoux C., Daumerie C., Rahier J., Geubel A.P., 2006. World Journal of Gastroenterology, 12 (38) pp. 6232-6234. Peer-reviewed.
 
Restorative proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis revisited.
Kartheuser A., Stangherlin P., Brandt D., Remue C., Sempoux C., 2006. Familial Cancer, 5 (3) pp. 241-60; discussion 261-2. Peer-reviewed.
 
Role of the pathologist in the differential diagnosis of malabsorption.
Sempoux C., 2006. Acta Gastro-enterologica Belgica, 69 (1) pp. 49-51. Peer-reviewed.
 
Solid and pseudopapillary tumor of the pancreas, review and new insights into pathogenesis.
Geers C., Moulin P., Pierre M., Gigot J.F., Jean-François G., Weynand B., Birgit W., Deprez P., Pierre D., Rahier J. et al., 2006. American Journal of Surgical Pathology, 30 (10) pp. 1243-1249. Peer-reviewed.
 
Superficial oeso-gastric cancer and endoscopic mucosal resection: the pathologist's approach.
Jouret A., Sempoux C., 2006. Acta Gastro-enterologica Belgica, 69 (3) pp. 299-303. Peer-reviewed.
 
The Knudson's two-hit model and timing of somatic mutation may account for the phenotypic diversity of focal congenital hyperinsulinism.
Giurgea I., Sempoux C., Bellanné-Chantelot C., Ribeiro M., Hubert L., Boddaert N., Saudubray J.M., Robert J.J., Brunelle F., Rahier J. et al., 2006. Journal of Clinical Endocrinology and Metabolism, 91 (10) pp. 4118-4123. Peer-reviewed.
 
What is the best way to predict disease-free survival after preoperative radiochemotherapy for rectal cancer patients: tumor regression grading, nodal status, or circumferential resection margin invasion?
Machiels J.P., Aydin S., Bonny M.A., Hammouch F., Sempoux C., 2006. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 24 (8) pp. 1319; author reply 1320-1319; author reply 1321. Peer-reviewed.
 
Bile duct carcinoid tumors: an uncommon disease but with a good prognosis?
Hubert C., Sempoux C., Berquin A., Deprez P., Jamar F., Gigot J.F., 2005. Hepato-gastroenterology, 52 (64) pp. 1042-1047. Peer-reviewed.
 
Blunted DNA synthesis and delayed S-phase entry following inhibition of Cdk2 activity in the regenerating rat liver.
Stärkel P., De Saeger C., Sempoux C., Legrand E., Leclercq I., Horsmans Y., 2005. Laboratory Investigation; A Journal of Technical Methods and Pathology, 85 (4) pp. 562-571. Peer-reviewed.
 
Disrupted NF- kappa B activation after partial hepatectomy does not impair hepatocyte proliferation in rats.
Laurent S., Horsmans Y., Stärkel P., Leclercq I., Sempoux C., Lambotte L., 2005. World Journal of Gastroenterology, 11 (46) pp. 7345-7350. Peer-reviewed.
 
Dominantly inherited hyperinsulinaemic hypoglycaemia.
de Lonlay P., Giurgea I., Sempoux C., Touati G., Jaubert F., Rahier J., Ribeiro M., Brunelle F., Nihoul-Fékété C., Robert J.J. et al., 2005. Journal of Inherited Metabolic Disease, 28 (3) pp. 267-276. Peer-reviewed.
 
Extensive ischemic liver necrosis complicating hereditary hemorrhagic telangiectasia: a rare indication for liver transplantation.
Dominguez I.B., Annet L., Waignein F., Sempoux C., Geubel A., 2005. Liver International : Official Journal of the International Association For the Study of the Liver, 25 (3) pp. 677-679. Peer-reviewed.
 
Factitious hyperinsulinism leading to pancreatectomy: severe forms of Munchausen syndrome by proxy.
Giurgea I., Ulinski T., Touati G., Sempoux C., Mochel F., Brunelle F., Saudubray J.M., Fekete C., de Lonlay P., 2005. Pediatrics, 116 (1) pp. e145-e148. Peer-reviewed.
 
Long-term medical complications and quality of life in adult recipients surviving 10 years or more after liver transplantation.
Ciccarelli O., Kaczmarek B., Roggen F., DeReyck C., Goffette P., Danse E., Verbaandert C., Sempoux C., Wittebole X., Wallemacq P. et al., 2005. Acta Gastro-enterologica Belgica, 68 (3) pp. 323-330. Peer-reviewed.
 
PET scan with 11C-acetate for the imaging of liver masses: report of a false positive case.
Lhommel R., Annet L., Bol A., Gigot J.F., Sempoux C., Mathieu I., Seret M., Lonneux M., 2005. European Journal of Nuclear Medicine and Molecular Imaging, 32 (5) p. 629. Peer-reviewed.
 
Phase II study of preoperative oxaliplatin, capecitabine and external beam radiotherapy in patients with rectal cancer: the RadiOxCape study.
Machiels J.P., Duck L., Honhon B., Coster B., Coche J.C., Scalliet P., Humblet Y., Aydin S., Kerger J., Remouchamps V. et al., 2005. Annals of Oncology : Official Journal of the European Society For Medical Oncology, 16 (12) pp. 1898-1905. Peer-reviewed.
 
Acute insulin responses to calcium and tolbutamide do not differentiate focal from diffuse congenital hyperinsulinism.
Giurgea I., Laborde K., Touati G., Bellanné-Chantelot C., Nassogne M.C., Sempoux C., Jaubert F., Khoa N., Chigot V., Rahier J. et al., 2004. Journal of Clinical Endocrinology and Metabolism, 89 (2) pp. 925-929. Peer-reviewed.
 
Adult liver transplantation at UCL: update 2002.
Lerut J., Matthys J., Lemaire J., Van Thuyne V., Ciccarelli O., Goffette P., Peeters A., Aunac S., Boddeus M., Carlier M.A. et al., 2004. Acta Gastro-enterologica Belgica, 67 (2) pp. 188-196. Peer-reviewed.
 
Curcumin inhibits NF-kappaB activation and reduces the severity of experimental steatohepatitis in mice.
Leclercq I.A., Farrell G.C., Sempoux C., dela Peña A., Horsmans Y., 2004. Journal of Hepatology, 41 (6) pp. 926-934. Peer-reviewed.
 
Diabète de type 2 et déficit des cellules B [Type 2 diabetes and B cell deficit].
Rahier J., Guiot Y., Sempoux C., 2004. Journees Annuelles De Diabetologie De L'hotel-dieu pp. 19-27. Peer-reviewed.
 
Endocrine tumours, somatostatin and somatostatin receptors.
Rahier J., Guiot Y., Sempoux C., 2004. Acta Gastro-enterologica Belgica, 67 (3) pp. 282-284. Peer-reviewed.
 
Focal and diffuse forms of congenital hyperinsulinism: the keys for differential diagnosis.
Sempoux C., Guiot Y., Jaubert F., Rahier J., 2004. Endocrine Pathology, 15 (3) pp. 241-246. Peer-reviewed.
 
Hepatic haemangioendothelioma in adults: excellent outcome following liver transplantation.
Lerut J.P., Orlando G., Sempoux C., Ciccarelli O., Van Beers B.E., Danse E., Horsmans Y., Rahier J., Roggen F., 2004. Transplant International : Official Journal of the European Society For Organ Transplantation, 17 (4) pp. 202-207. Peer-reviewed.
 
Histological scoring of chronic hepatitis.
Sempoux C., Rahier J., 2004. Acta Gastro-enterologica Belgica, 67 (3) pp. 290-293. Peer-reviewed.
 
Hyperinsulinemic hypoglycemia in children.
de Lonlay P., Giurgea I., Robert J.J., Fournet J.C., Touati G., Nihoul-Fékété C., Brunelle F., Jaubert F., Rahier J., Sempoux C. et al., 2004. Annales D'endocrinologie, 65 (1) pp. 96-98. Peer-reviewed.
 
Intranuclear biotin.
Marbaix E., Waignein F., Camby P., Lopez de la Osa Escribano I., Bernard P., Sempoux C., 2004. Lancet (london, England), 364 (9433) p. 532. Peer-reviewed.
 
Molecular mechanisms of apoptosis in the liver of rats after portal branch ligation with and without retrorsine.
Picard C., Starkel P., Sempoux C., Saliez A., Lebrun V., Horsmans Y., 2004. Laboratory Investigation; A Journal of Technical Methods and Pathology, 84 (5) pp. 618-628. Peer-reviewed.
 
Successful treatment of recurrent cholangitis after adult liver transplantation with a Tsuchida antireflux valve.
Orlando G., Blairvacq J.S., Otte J.B., Goffette P., Ciccarelli O., Sempoux C., Lerut J., 2004. Transplantation, 77 (8) pp. 1307-1308. Peer-reviewed.
 
The paediatric liver transplantation program at the Université catholique de Louvain.
Reding R., Bourdeaux C., Gras J., Evrard V., Buts J.P., Carlier M., Ciccarelli O., Clapuyt P., de Clety S.C., De Kock M. et al., 2004. Acta Gastro-enterologica Belgica, 67 (2) pp. 176-178. Peer-reviewed.
 
Bile duct disorders.
Geubel A.P., Sempoux C., Rahier J., 2003. Clinics In Liver Disease, 7 (2) pp. 295-309. Peer-reviewed.
 
Capillarization of the sinusoids in liver fibrosis: noninvasive assessment with contrast-enhanced MRI in the rabbit.
Van Beers B.E., Materne R., Annet L., Hermoye L., Sempoux C., Peeters F., Smith A.M., Jamart J., Horsmans Y., 2003. Magnetic Resonance In Medicine, 49 (4) pp. 692-699. Peer-reviewed.
 
Glycogenosis storage type I diseases and evolutive adenomatosis: an indication for liver transplantation.
Lerut J.P., Ciccarelli O., Sempoux C., Danse E., deFlandre J., Horsmans Y., Sokal E., Otte J.B., 2003. Transplant International : Official Journal of the European Society For Organ Transplantation, 16 (12) pp. 879-884. Peer-reviewed.
 
Hyperinsulinisme néonatal persistant: les nouvelles découvertes en pathologie eclairent la pathophysiologie du syndrome et en dirigent l'approche thérapeutique [Persistent neonatal hyperinsulinism: new pathological findings which clarify the physiopathology of the syndrome and direct the therapeutic approach].
Sempoux C.h., 2003. Bulletin et Memoires De L'academie Royale De Medecine De Belgique, 158 (5-6) pp. 291-297. Peer-reviewed.
 
Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats.
Stärkel P., Sempoux C., Leclercq I., Herin M., Deby C., Desager J.P., Horsmans Y., 2003. Journal of Hepatology, 39 (4) pp. 538-546. Peer-reviewed.
 
Retrorsine: a kinetic study of its influence on rat liver regeneration in the portal branch ligation model.
Picard C., Lambotte L., Starkel P., Sempoux C., Saliez A., Van Den Berge V., de Saeger C., Horsmans Y., 2003. Journal of Hepatology, 39 (1) pp. 99-105. Peer-reviewed.
 
Scanner multidétecteur face à l'IRM dans les tumeurs bénignes du foie [Multidetector CT and MRI of benign liver tumors].
Van Beers B., Horsmans Y., Sempoux C., 2003. Journal De Radiologie, 84 (4 Pt 2) pp. 445-56; discussion 457-8. Peer-reviewed.
 
The focal form of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma.
Sempoux C., Guiot Y., Dahan K., Moulin P., Stevens M., Lambot V., de Lonlay P., Fournet J.C., Junien C., Jaubert F. et al., 2003. Diabetes, 52 (3) pp. 784-794. Peer-reviewed.
 
Dynamic computed tomography with low- and high-molecular-mass contrast agents to assess microvascular permeability modifications in a model of liver fibrosis.
Materne R., Annet L., Dechambre S., Sempoux C., Smith A.M., Corot C., Horsmans Y., Van Beers B.E., 2002. Clinical Science (london, England : 1979), 103 (2) pp. 213-216. Peer-reviewed.
 
Expression of cholecystokinin in the duodenum of patients with coeliac disease: respective role of atrophy and lymphocytic infiltration.
Deprez P.H., Sempoux C., De Saeger C., Rahier J., Mainguet P., Pauwels S., Geubel A., 2002. Clinical Science (london, England : 1979), 103 (2) pp. 171-177. Peer-reviewed.
 
Expérience du pathologiste dans l'hypoglycémie hyperinsulinique néonatale persistante [Persistent hyperinsulinemic hypoglycemia of infancy: the pathologist's experience].
Sempoux C., Guiot Y., Noël H., Jaubert F., Rahier J., 2002. Annales De Pathologie, 22 (5) pp. 375-386. Peer-reviewed.
 
Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases.
de Lonlay P., Fournet J.C., Touati G., Groos M.S., Martin D., Sevin C., Delagne V., Mayaud C., Chigot V., Sempoux C. et al., 2002. European Journal of Pediatrics, 161 (1) pp. 37-48. Peer-reviewed.
 
Persistent decreased plasma cholecystokinin levels in celiac patients under gluten-free diet: respective roles of histological changes and nutrient hydrolysis.
Deprez P., Sempoux C., Van Beers B.E., Jouret A., Robert A., Rahier J., Geubel A., Pauwels S., Mainguet P., 2002. Regulatory Peptides, 110 (1) pp. 55-63. Peer-reviewed.
 
Potentiation of 2,2-dichloro-1,1,1-trifluoroethane (HCFC-123)-induced liver toxicity by ethanol in guinea-pigs.
Hoet P., Buchet J.P., Sempoux C., Haufroid V., Rahier J., Lison D., 2002. Archives of Toxicology, 76 (12) pp. 707-714. Peer-reviewed.
 
Steatosis is not sufficient to cause an impaired regenerative response after partial hepatectomy in rats.
Picard C., Lambotte L., Starkel P., Sempoux C., Saliez A., Van den Berge V., Horsmans Y., 2002. Journal of Hepatology, 36 (5) pp. 645-652. Peer-reviewed.
 
Which type of dialysis in patients with cholesterol crystal embolism?
Gillerot G., Sempoux C., Pirson Y., Devuyst O., 2002. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 17 (1) pp. 156-158. Peer-reviewed.
 
Adult liver transplantation and steroid-azathioprine withdrawal in cyclosporine (Sandimmun)-based immunosuppression - 5 year results of a prospective study.
Lerut J.P., Ciccarelli O., Mauel E., Gheerardhyn R., Talpe S., Sempoux C., Laterre P.F., Roggen F.M., Van Leeuw V., Otte J.B. et al., 2001. Transplant International : Official Journal of the European Society For Organ Transplantation, 14 (6) pp. 420-428. Peer-reviewed.
 
After portal branch ligation in the rat, cellular proliferation is associated with selective induction of c-Ha-ras, p53, cyclin E, and Cdk2.
Stärkel P., Lambotte L., Sempoux C., De Saeger C., Saliez A., Maiter D., Horsmans Y., 2001. Gut, 49 (1) pp. 119-130. Peer-reviewed.
 
Biodistribution of ultrasmall iron oxide particles in the rat liver.
Van Beers B.E., Sempoux C., Materne R., Delos M., Smith A.M., 2001. Journal of Magnetic Resonance Imaging : Jmri, 13 (4) pp. 594-599. Peer-reviewed.
 
Early oesophageal cancer demonstrated by double-contrast barium oesophagography.
Coche E., Sempoux C., Goncette L., 2001. Jbr-btr : Organe De La Societe Royale Belge De Radiologie (srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (kbvr), 84 (3) p. 124. Peer-reviewed.
 
Human type 2 diabetes: morphological evidence for abnormal beta-cell function.
Sempoux C., Guiot Y., Dubois D., Moulin P., Rahier J., 2001. Diabetes, 50 Suppl 1 pp. S172-S177. Peer-reviewed.
 
Investigations on the liver toxicity of a blend of HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) and HCFC-124 (2-chloro-1,1,1,2-tetrafluoroethane) in guinea-pigs.
Hoet P., Buchet J.P., Sempoux C., Nomiyama T., Rahier J., Lison D., 2001. Archives of Toxicology, 75 (5) pp. 274-283. Peer-reviewed.
 
No decrease of the beta-cell mass in type 2 diabetic patients.
Guiot Y., Sempoux C., Moulin P., Rahier J., 2001. Diabetes, 50 Suppl 1 pp. S188. Peer-reviewed.
 
Posttransplant immune hepatitis in pediatric liver transplant recipients: incidence and maintenance therapy with azathioprine.
Andries S., Casamayou L., Sempoux C., Burlet M., Reding R., Bernard Otte J., Buts J.P., Sokal E., 2001. Transplantation, 72 (2) pp. 267-272. Peer-reviewed.
 
Posttransplant lymphoproliferative disorder after liver transplantation in miniature swine.
Talpe S., Oike F., Dehoux J.P., Sempoux C., Rahier J., Otte J.B., Gianello P., 2001. Transplantation, 71 (11) pp. 1684-1688. Peer-reviewed.
 
Surgical management of intraductal papillary mucinous tumors of the pancreas: the role of routine frozen section of the surgical margin, intraoperative endoscopic staged biopsies of the Wirsung duct, and pancreaticogastric anastomosis.
Gigot J.F., Deprez P., Sempoux C., Descamps C., Metairie S., Glineur D., Gianello P., 2001. Archives of Surgery (chicago, Ill. : 1960), 136 (11) pp. 1256-1262. Peer-reviewed.
 
The focal form of persistent hyperinsulinemic hypoglycemia of infancy.
Sempoux C., Guiot Y., Rahier J., 2001. Diabetes, 50 Suppl 1 pp. S182-S183. Peer-reviewed.
 
The surgical management of congenital liver cysts.
Gigot J.F., Metairie S., Etienne J., Horsmans Y., van Beers B.E., Sempoux C., Deprez P., Materne R., Geubel A., Glineur D. et al., 2001. Surgical Endoscopy, 15 (4) pp. 357-363. Peer-reviewed.
 
Angiomyolipoma of the liver: ferumoxides-enhanced MR imaging.
Ketelslegers E., Van Beers B.E., Sempoux C., 2000. European Radiology, 10 (9) pp. 1401-1403. Peer-reviewed.
 
Drug and toxin-induced bile duct disorders.
Geubel A.P., Sempoux C.L., 2000. Journal of Gastroenterology and Hepatology, 15 (11) pp. 1232-1238. Peer-reviewed.
 
Focal nodular hyperplasia: natural course observed with CT and MRI.
Leconte I., Van Beers B.E., Lacrosse M., Sempoux C., Jamart J., Materne R., Baudrez V., Horsmans Y., 2000. Journal of Computer Assisted Tomography, 24 (1) pp. 61-66. Peer-reviewed.
 
Persistent hyperinsulinaemic hypoglycaemia of infancy: a heterogeneous syndrome unrelated to nesidioblastosis.
Rahier J., Guiot Y., Sempoux C., 2000. Archives of Disease In Childhood. Fetal and Neonatal Edition, 82 (2) pp. F108-F112. Peer-reviewed.
 
Sclerosing cholangitis associated to cryptosporidiosis in liver-transplanted children.
Campos M., Jouzdani E., Sempoux C., Buts J.P., Reding R., Otte J.B., Sokal E.M., 2000. European Journal of Pediatrics, 159 (1-2) pp. 113-115. Peer-reviewed.
 
The compensatory hyperplasia (liver regeneration) following ligation of a portal branch is initiated before the atrophy of the deprived lobes.
Lambotte L., Li B., Leclercq I., Sempoux C., Saliez A., Horsmans Y., 2000. Journal of Hepatology, 32 (6) pp. 940-945. Peer-reviewed.
 
Adult liver transplantation: UCL experience.
Lerut J., Laterre P.F., Roggen F., Ciccarelli O., Donataccio M., Martinez J., de Ville de Goyet J., Reding R., Carlier M.A., Dekock M. et al., 1999. Acta Gastro-enterologica Belgica, 62 (3) pp. 306-318. Peer-reviewed.
 
After portal branch ligation in rat, nuclear factor kappaB, interleukin-6, signal transducers and activators of transcription 3, c-fos, c-myc, and c-jun are similarly induced in the ligated and nonligated lobes.
Stärkel P., Horsmans Y., Sempoux C., De Saeger C., Wary J., Lause P., Maiter D., Lambotte L., 1999. Hepatology (baltimore, Md.), 29 (5) pp. 1463-1470. Peer-reviewed.
 
Atorvastatin-induced acute hepatitis with absence of cross-toxicity with simvastatin.
Nakad A., Bataille L., Hamoir V., Sempoux C., Horsmans Y., 1999. Lancet (london, England), 353 (9166) pp. 1763-1764. Peer-reviewed.
 
Clinical features of 52 neonates with hyperinsulinism.
de Lonlay-Debeney P., Poggi-Travert F., Fournet J.C., Sempoux C., Dionisi Vici C., Brunelle F., Touati G., Rahier J., Junien C., Nihoul-Fékété C. et al., 1999. New England Journal of Medicine, 340 (15) pp. 1169-1175. Peer-reviewed.
 
Colorectal villous tumors accuracy of the preoperative biopsies.
Detry R., Kartheuser A., Hermans B.P., Lagneaux G., Sempoux C., 1999. Acta Gastro-enterologica Belgica, 62 (1) pp. 9-12. Peer-reviewed.
 
CYP 3A proteins are expressed in human neutrophils and lymphocytes but are not induced by rifampicin.
Stärkel P., Sempoux C., Van Den Berge V., Stevens M., De Saeger C., Desager J.P., Horsmans Y., 1999. Life Sciences, 64 (8) pp. 643-653. Peer-reviewed.
 
Cytochrome P450 3A proteins are expressed in B lymphocytes but not in T lymphocytes.
Sempoux C., Stärkel P., Stevens M., Van Den Berge V., Horsmans Y., 1999. Pharmacogenetics, 9 (2) pp. 263-265. Peer-reviewed.
 
HLA association of amoxicillin-clavulanate--induced hepatitis.
Hautekeete M.L., Horsmans Y., Van Waeyenberge C., Demanet C., Henrion J., Verbist L., Brenard R., Sempoux C., Michielsen P.P., Yap P.S. et al., 1999. Gastroenterology, 117 (5) pp. 1181-1186. Peer-reviewed.
 
Venlafaxine-associated hepatitis.
Horsmans Y., De Clercq M., Sempoux C., 1999. Annals of Internal Medicine, 130 (11) p. 944. Peer-reviewed.
 
Acute hepatitis due to poisoning.
Geubel A.P., Mahieu P., Dive A., Hantson P., Sempoux C., Rahier J., 1998. Acta Gastro-enterologica Belgica, 61 (4) pp. 468-469. Peer-reviewed.
 
Neonatal hyperinsulinemic hypoglycemia: heterogeneity of the syndrome and keys for differential diagnosis.
Sempoux C., Guiot Y., Lefevre A., Nihoul-Fékété C., Jaubert F., Saudubray J.M., Rahier J., 1998. Journal of Clinical Endocrinology and Metabolism, 83 (5) pp. 1455-1461. Peer-reviewed.
 
Pancreatic B-cell proliferation in persistent hyperinsulinemic hypoglycemia of infancy: an immunohistochemical study of 18 cases.
Sempoux C., Guiot Y., Dubois D., Nollevaux M.C., Saudubray J.M., Nihoul-Fekete C., Rahier J., 1998. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc, 11 (5) pp. 444-449. Peer-reviewed.
 
Paracetamol-induced liver toxicity after intravenous administration.
Horsmans Y., Sempoux C., Detry R., Geubel A.P., 1998. Liver, 18 (4) pp. 294-295. Peer-reviewed.
 
Partial or near-total pancreatectomy for persistent neonatal hyperinsulinaemic hypoglycaemia: the pathologist's role.
Rahier J., Sempoux C., Fournet J.C., Poggi F., Brunelle F., Nihoul-Fekete C., Saudubray J.M., Jaubert F., 1998. Histopathology, 32 (1) pp. 15-19. Peer-reviewed.
 
Acute lobular hepatitis as the first manifestation of recurrent autoimmune hepatitis after orthotopic liver transplantation.
Sempoux C., Horsmans Y., Lerut J., Rahier J., Geubel A., 1997. Liver, 17 (6) pp. 311-315. Peer-reviewed.
 
Angiomyolipoma of the liver: an unusual benign tumour identifiable on cytological material.
Sempoux C., Weynand B., van Beers B.E., Lefebvre C., Galant C., 1997. Cytopathology : Official Journal of the British Society For Clinical Cytology, 8 (3) pp. 196-202. Peer-reviewed.
 
Hyperplasie adénomateuse du pancréas et mort subite du nourrisson [Pancreatic adenomatous hyperplasia and sudden infant death].
Léger-Ravet M.B., Bouillie C., Sempoux C., Rahier J., Faucher J.N., 1997. Annales De Pathologie, 17 (3) pp. 206-208. Peer-reviewed.
 
Severe radiation-induced liver disease following localized radiation therapy for biliopancreatic carcinoma: activation of hepatic stellate cells as an early event.
Sempoux C., Horsmans Y., Geubel A., Fraikin J., Van Beers B.E., Gigot J.F., Lerut J., Rahier J., 1997. Hepatology (baltimore, Md.), 26 (1) pp. 128-134. Peer-reviewed.
 
Hepatic angiomyo(myelo)lipoma: difficulties in radiological diagnosis and interest of fine needle aspiration biopsy.
Messiaen T., Lefebvre C., Van Beers B., Sempoux C., Cosyns J.P., Geubel A., 1996. Liver, 16 (5) pp. 338-341. Peer-reviewed.
 
Influence des médications locales sur le contrôle de la pression intra-oculaire après trabéculectomie [Effect of local medications on intraocular pressure control following trabeculectomy].
Detry-Morel M., Boschi A., Sempoux P., Hoebeke M., Sempoux C., Marbaix E., Ilunga J., Bouckaert A., 1995. Bulletin De La Societe Belge D'ophtalmologie, 259 pp. 135-141. Peer-reviewed.
 
Nesidioblastosis and persistent neonatal hyperinsulinism.
Sempoux C., Poggi F., Brunelle F., Saudubray J.M., Fekete C., Rahier J., 1995. Diabete and Metabolisme, 21 (6) pp. 402-407. Peer-reviewed.
 
Nésidioblastose et hyperinsulinisme néonatal persistant [Nesidioblastosis and persistent neonatal hyperinsulinism].
Rahier J., Sempoux C., Poggi F., Brunelle F., Saudubray J.M., Fekete C., 1995. pp. 73-82 dans Journée annuelles de diabétologie de l'Hôtel-Dieu 1995. Peer-reviewed.
 
Ostéosarcome primitif de l'oreillette gauche. A propos d'une observation [Primary osteosarcoma of the left auricle. Report of a case].
Hantson P., Ghilain J.M., Galant C., Sempoux C., Mahieu P., Geeraerts G., Lefebvre C., 1995. Annales De Pathologie, 15 (1) pp. 50-52. Peer-reviewed.
 
Conversion from cyclosporine to FK506 for salvage of immunocompromised pediatric liver allografts. Efficacy, toxicity, and dose regimen in 23 children.
Reding R., Wallemacq P.E., Lamy M.E., Rahier J., Sempoux C., Debande B., Jamart J., Barker A., Sokal E., De Ville de Goyet J., 1994. Transplantation, 57 (1) pp. 93-100. Peer-reviewed.
 
Nonossifying fibromyxoid tumor of soft tissue.
Leray V., Gosseye S., Sempoux C., Ninane J., Vanwijck R., 1994. Pediatric Hematology and Oncology, 11 (4) pp. 451-454. Peer-reviewed.
 
Hépatite à la benzarone: un deuxième cas [Hepatitis caused by benzarone: a second case].
Nakad A., Azzouzi K., Gerbaux A., Delcourt A., Sempoux C., Tamo F., Rahier J., Geubel A.P., 1990. Gastroenterologie Clinique et Biologique, 14 (10) pp. 782-784. Peer-reviewed.
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