Christine Sempoux

Publications | Phd and Masters theses

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290 publications

2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | ...
CD73 expression in normal, hyperplastic, and neoplastic thyroid: a systematic evaluation revealing CD73 overexpression as a feature of papillary carcinomas.
Monteiro I., Missiaglia E., Sciarra A., Santos J.V., Bouilly J., Romero P., Sempoux C., de Leval L., 2021/05/21. Virchows Archiv. Peer-reviewed.
Immune cell infiltration in colonic cancer: correlation between biopsy and surgical specimens.
Bordry N., Germann M., Foukas P.G., Sempoux C., Yan P., Dormond O., Speiser D.E., Demartines N., Sauvain M.O., 2021/04/30. The British journal of surgery, 108 (4) pp. 346-350. Peer-reviewed.
Autochthonous hepatitis E as a cause of acute-on-chronic liver failure and death: histopathology can be misleading but transaminases may provide a clue.
Vieira Barbosa J., Müllhaupt B., Brunner F., Filipowicz Sinnreich M., Semela D., Montani M., Cathomas G., Neuweiler J., Gouttenoire J., Artru F. et al., 2021/04/26. Swiss medical weekly, 151 pp. w20502. Peer-reviewed.
Reproducibility of tumor budding assessment in pancreatic cancer based on a multicenter interobserver study.
Karamitopoulou E., Esposito I., Zlobec I., Insilla A.C., Wartenberg M., Schaeffer D.F., Kalloger S., La Rosa S., Sempoux C., Ramos Centeno I. et al., 2021/04. Virchows Archiv, 478 (4) pp. 719-726. Peer-reviewed.
Personalized Cytokine-Directed Therapy With Tocilizumab for Refractory Immune Checkpoint Inhibitor-Related Cholangiohepatitis.
Moi L., Bouchaab H., Mederos N., Nguyen-Ngoc T., Perreau M., Fenwick C., Vaucher J., Sempoux C., Peters S., Obeid M., 2021/02. Journal of thoracic oncology, 16 (2) pp. 318-326. Peer-reviewed.
Prediction of tumour grade and survival outcome using pre-treatment PET- and MRI-derived imaging features in patients with resectable pancreatic ductal adenocarcinoma.
Dunet V., Halkic N., Sempoux C., Demartines N., Montemurro M., Prior J.O., Schmidt S., 2021/02. European radiology, 31 (2) pp. 992-1001. Peer-reviewed.
Autoimmune hepatitis as a sequelae of oxcarbazepine-induced drug reaction with eosinophilia and systemic symptoms.
Droz N., Chevrier F., Lapointe A.K., Sempoux C., Fraga M., Comte D., 2021/01. The journal of allergy and clinical immunology. In practice, 9 (1) pp. 580-581. Peer-reviewed.
The histologic presentation of hepatitis E reflects patients' immune status and pre-existing liver condition.
Lenggenhager D., Pawel S., Honcharova-Biletska H., Evert K., Wenzel J.J., Montani M., Furrer E., Fraga M., Moradpour D., Sempoux C. et al., 2021/01. Modern pathology, 34 (1) pp. 233-248. Peer-reviewed.
Development of an optimized closed and semi-automatic protocol for Good Manufacturing Practice manufacturing of tumor-infiltrating lymphocytes in a hospital environment.
Gannon P.O., Harari A., Auger A., Murgues C., Zangiacomi V., Rubin O., Ellefsen Lavoie K., Guillemot L., Navarro Rodrigo B., Nguyen-Ngoc T. et al., 2020/12. Cytotherapy, 22 (12) pp. 780-791. Peer-reviewed.
Incidence trends of lung and gastroenteropancreatic neuroendocrine neoplasms in Switzerland.
Alwan H., La Rosa S., Andreas Kopp P., Germann S., Maspoli-Conconi M., Sempoux C., Bulliard J.L., 2020/12. Cancer medicine, 9 (24) pp. 9454-9461. Peer-reviewed.
Hepatocellular type II fibrinogen inclusions in a patient with severe COVID-19 and hepatitis.
Fraga M., Moradpour D., Artru F., Romailler E., Tschopp J., Schneider A., Chtioui H., Neerman-Arbez M., Casini A., Alberio L. et al., 2020/10. Journal of hepatology, 73 (4) pp. 967-970. Peer-reviewed.
Solute carrier family 12 member 2 as a proteomic and histological biomarker of dysplasia and neoplasia in ulcerative colitis.
Merli A.M., Vieujean S., Massot C., Blétard N., Quesada Calvo F., Baiwir D., Mazzucchelli G., Servais L., Wéra O., Oury C. et al., 2020/09/13. Journal of Crohn's & colitis. Peer-reviewed.
Adénomes hépatocellulaires : update 2020 [Hepatocellular adenoma: update 2020]
Romailler E., Schmidt Kobbe S., Moradpour D., Sempoux C., 2020/09/02. Revue medicale suisse, 16 (704) pp. 1554-1559. Peer-reviewed.
Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Moschouri E., Vionnet J., Giostra E., Daccord C., Lazor R., Sciarra A., Letovanec I., Sempoux C., Gonzalez M., Unger S. et al., 2020/06. Liver transplantation, 26 (6) pp. 840-844. Peer-reviewed.
Tumor response and outcome after reverse treatment for patients with synchronous colorectal liver metastasis: a cohort study.
Du Pasquier C., Roulin D., Bize P., Sempoux C., Rebecchini C., Montemurro M., Schäfer M., Halkic N., Demartines N., 2020/04/19. BMC surgery, 20 (1) p. 78. Peer-reviewed.
Gallbladder Mixed Neuroendocrine-Non-neuroendocrine Neoplasm (MiNEN) Arising in Intracholecystic Papillary Neoplasm: Clinicopathologic and Molecular Analysis of a Case and Review of the Literature.
Sciarra A., Missiaglia E., Trimech M., Melloul E., Brouland J.P., Sempoux C., La Rosa S., 2020/03. Endocrine pathology, 31 (1) pp. 84-93. Peer-reviewed.
Updates in the diagnosis of combined hepatocellular-cholangiocarcinoma.
Sciarra A., Park Y.N., Sempoux C., 2020/02. Human pathology, 96 pp. 48-55. Peer-reviewed.
Neutrophils suppress tumor-infiltrating T cells in colon cancer via matrix metalloproteinase-mediated activation of TGFβ.
Germann M., Zangger N., Sauvain M.O., Sempoux C., Bowler A.D., Wirapati P., Kandalaft L.E., Delorenzi M., Tejpar S., Coukos G. et al., 2020/01/09. EMBO molecular medicine, 12 (1) pp. e10681. Peer-reviewed.
Donor-specific antibodies in liver transplantation.
Vionnet J., Sempoux C., Pascual M., Sánchez-Fueyo A., Colmenero J., 2020/01. Gastroenterologia y hepatologia, 43 (1) pp. 34-45. Peer-reviewed.
Acinar cell carcinoma of the pancreas with thyroid-like follicular features: first description of a new diagnostic challenging subtype.
Saglietti C., Schneider V., Bongiovanni M., Missiaglia E., Bisig B., Dorta G., Demartines N., Sempoux C., La Rosa S., 2019/12. Virchows Archiv, 475 (6) pp. 789-794. Peer-reviewed.
A Phase I/II trial comparing autologous dendritic cell vaccine pulsed either with personalized peptides (PEP-DC) or with tumor lysate (OC-DC) in patients with advanced high-grade ovarian serous carcinoma.
Sarivalasis A., Boudousquié C., Balint K., Stevenson B.J., Gannon P.O., Iancu E.M., Rossier L., Martin Lluesma S., Mathevet P., Sempoux C. et al., 2019/11/26. Journal of translational medicine, 17 (1) p. 391. Peer-reviewed.
Synchronous tumors of the pancreas and the gallbladder: a case report with targeted NGS evaluation.
Sivade A., Sempoux C., Voutsadakis I., Brunel C., Halkic N., Godat S., Duran R., Digklia A., 2019/11. Annals of translational medicine, 7 (22) p. 696. Peer-reviewed.
Synchronous tumors of the pancreas and the gallbladder: a case report with targeted NGS evaluation.
Sivade A., Sempoux C., Voutsadakis I., Brunel C., Halkic N., Godat S., Duran R., Digklia A., 2019/11. Annals of translational medicine, 7 (22) p. 696. Peer-reviewed.
ABC des polypes coliques [Abecedary of colonic polyps]
Archanioti P., Bornand A., Sempoux C., Unger S., Schoepfer A., Robert M., David G., 2019/08/28. Revue medicale suisse, 15 (660) pp. 1483-1487. Peer-reviewed.
Syndrome d’Alagille [Alagille Syndrome]
Wakim El-Khoury J., Venetz J.P., Rutz T., Sciarra A., Unger S., Sempoux C., Moradpour D., Fraga M., 2019/08/28. Revue medicale suisse, 15 (660) pp. 1506-1510. Peer-reviewed.
A Phase Ib Study of the Combination of Personalized Autologous Dendritic Cell Vaccine, Aspirin, and Standard of Care Adjuvant Chemotherapy Followed by Nivolumab for Resected Pancreatic Adenocarcinoma—A Proof of Antigen Discovery Feasibility in Three Patients
Bassani-Sternberg Michal, Digklia Antonia, Huber Florian, Wagner Dorothea, Sempoux Christine, Stevenson Brian J., Thierry Anne-Christine, Michaux Justine, Pak HuiSong, Racle Julien et al., 2019/08/08. Frontiers in Immunology, 10 p. 1832. Peer-reviewed.
Invasive Ductular Reaction Operates Hepatobiliary Junctions upon Hepatocellular Injury in Rodents and Humans.
Clerbaux L.A., Manco R., Van Hul N., Bouzin C., Sciarra A., Sempoux C., Theise N.D., Leclercq I.A., 2019/08. The American journal of pathology, 189 (8) pp. 1569-1581. Peer-reviewed.
Primary hepatic marginal B cell lymphoma of mucosa-associated lymphoid tissue (MALT) and non-alcoholic steatohepatitis (NASH): more than a coincidence?
Haefliger S., Milowich D., Sciarra A., Trimeche M., Bouilly J., Kaiser J., Volpi S., Brouland J.P., Sempoux C., de Leval L., 2019/06. Annals of hematology, 98 (6) pp. 1513-1516. Peer-reviewed.
Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury.
Manco R., Clerbaux L.A., Verhulst S., Bou Nader M., Sempoux C., Ambroise J., Bearzatto B., Gala J.L., Horsmans Y., van Grunsven L. et al., 2019/06. Journal of hepatology, 70 (6) pp. 1180-1191. Peer-reviewed.
Reproducibility of the peritoneal regression grading score for assessment of response to therapy in peritoneal metastasis.
Solass W., Sempoux C., Carr N.J., Bibeau F., Neureiter D., Jäger T., Di Caterino T., Brunel C., Klieser E., Fristrup C.W. et al., 2019/06. Histopathology, 74 (7) pp. 1014-1024. Peer-reviewed.
CD73 expression in normal and pathological human hepatobiliopancreatic tissues.
Sciarra A., Monteiro I., Ménétrier-Caux C., Caux C., Gilbert B., Halkic N., La Rosa S., Romero P., Sempoux C., de Leval L., 2019/03. Cancer immunology, immunotherapy, 68 (3) pp. 467-478. Peer-reviewed.
Correction to: CD73 expression in normal and pathological human hepatobiliopancreatic tissues
Sciarra Amedeo, Monteiro Inês, Ménétrier-Caux Christine, Caux Christophe, Gilbert Benoit, Halkic Nermin, La Rosa Stefano, Romero Pedro, Sempoux Christine, de Leval Laurence, 2019/03. 1.
Lokal fortgeschrittenes mit neoadjuvanter Radiochemotherapie behandeltes Rektumkarzinom (LFRK): Histopathologische Korrelation von diffusionsgewichteter Magnetresonanztomographie und multiparametrischer PET/CT [Response of locally advanced rectal cancer (LARC) to radiochemotherapy: DW-MRI and multiparametric PET/CT in correlation with histopathology]
Cerny M., Dunet V., Rebecchini C., Hahnloser D., Prior J., Sempoux C., Schmidt S., 2019/02. Nuklearmedizin. Nuclear medicine, 58 (1) pp. 28-38. Peer-reviewed.
Snapshot summary of diagnosis and management of hepatocellular adenoma subtypes.
Bioulac-Sage P., Sempoux C., Frulio N., Le Bail B., Blanc J.F., Castain C., Laurent C., Trillaud H., Chiche L., Balabaud C., 2019/02. Clinics and research in hepatology and gastroenterology, 43 (1) pp. 12-19. Peer-reviewed.
Histology of portal vascular changes associated with idiopathic non-cirrhotic portal hypertension: nomenclature and definition.
Guido M., Alves VAF, Balabaud C., Bathal P.S., Bioulac-Sage P., Colombari R., Crawford J.M., Dhillon A.P., Ferrell L.D., Gill R.M. et al., 2019/01. Histopathology, 74 (2) pp. 219-226. Peer-reviewed.
OATPB1/B3 and MRP3 expression in hepatocellular adenoma predicts Gd-EOB-DTPA uptake and correlates with risk of malignancy.
Sciarra A., Schmidt S., Pellegrinelli A., Maggioni M., Dondossola D., Pasquier J., Cigala C., Tosi D., Halkic N., Bulfamante G. et al., 2019/01. Liver international, 39 (1) pp. 158-167. Peer-reviewed.
Hepatic manifestations of Wilson's disease: 12-year experience in a Swiss tertiary referral centre.
Vieira Barbosa J., Fraga M., Saldarriaga J., Hiroz P., Giostra E., Sempoux C., Ferenci P., Moradpour D., 2018/12/17. Swiss medical weekly, 148 pp. w14699. Peer-reviewed.
Local recurrence rate in patients with colorectal cancer liver metastasis after wedge resection or percutaneous radiofrequency ablation.
Vietti Violi N., Duran R., Demartines N., Sempoux C., Guiu B., Bize P.E., Sala N., Halkic N., Knebel J.F., Denys A., 2018/11. International journal of hyperthermia, 34 (7) pp. 1020-1028. Peer-reviewed.
β-Klotho deficiency shifts the gut-liver bile acid axis and induces hepatic alterations in mice.
Somm E., Henry H., Bruce S.J., Bonnet N., Montandon S.A., Niederländer N.J., Messina A., Aeby S., Rosikiewicz M., Fajas L. et al., 2018/11/01. American journal of physiology. Endocrinology and metabolism, 315 (5) pp. E833-E847. Peer-reviewed.
Impact of biological agents on the prevalence of chemotherapy associated liver injury (CALI): Multicentric study of patients operated for colorectal liver metastases.
Hubert C., Lucidi V., Weerts J., Dili A., Demetter P., Massart B., Komuta M., Navez J., Reding R., Gigot J.F. et al., 2018/10. European journal of surgical oncology, 44 (10) pp. 1532-1538. Peer-reviewed.
Cholangite biliaire primitive : mise à jour [Primary biliary cholangitis : an update]
Vieira Barbosa J., Vionnet J., Sciarra A., Sempoux C., Aubert V., Moradpour D., Fraga Christinet M., 2018/08/29. Revue medicale suisse, 14 (616) pp. 1489-1494. Peer-reviewed.
cHCC-CCA: Consensus terminology for primary liver carcinomas with both hepatocytic and cholangiocytic differentation.
Brunt E., Aishima S., Clavien P.A., Fowler K., Goodman Z., Gores G., Gouw A., Kagen A., Klimstra D., Komuta M. et al., 2018/07. Hepatology, 68 (1) pp. 113-126. Peer-reviewed.
Hepatocellular nodules in vascular liver diseases.
Sempoux C., Balabaud C., Paradis V., Bioulac-Sage P., 2018/07. Virchows Archiv, 473 (1) pp. 33-44. Peer-reviewed.
Vascular liver lesions: contemporary views on long-recognized entities.
Sempoux C., Bioulac-Sage P., 2018/07. Virchows Archiv, 473 (1) pp. 1-2. Peer-reviewed.
Acute-on-chronic liver failure 2018: a need for (urgent) liver biopsy?
van Leeuwen D.J., Alves V., Balabaud C., Bhathal P.S., Bioulac-Sage P., Colombari R., Crawford J.M., Dhillon A.P., Ferrell L., Gill R.M. et al., 2018/06. Expert review of gastroenterology & hepatology, 12 (6) pp. 565-573. Peer-reviewed.
Quantification of hepatic perfusion and hepatocyte function with dynamic gadoxetic acid-enhanced MRI in patients with chronic liver disease.
Leporq B., Daire J.L., Pastor C.M., Deltenre P., Sempoux C., Schmidt S., Van Beers B.E., 2018/04/16. Clinical science, 132 (7) pp. 813-824. Peer-reviewed.
Combination of Gene Expression Signature and Model for End-Stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis.
Trépo E., Goossens N., Fujiwara N., Song W.M., Colaprico A., Marot A., Spahr L., Demetter P., Sempoux C., Im G.Y. et al., 2018/03. Gastroenterology, 154 (4) pp. 965-975. Peer-reviewed.
Eosinophilic Esophagitis: Relationship of Subepithelial Eosinophilic Inflammation With Epithelial Histology, Endoscopy, Blood Eosinophils, and Symptoms.
Schoepfer A.M., Simko A., Bussmann C., Safroneeva E., Zwahlen M., Greuter T., Biedermann L., Vavricka S., Godat S., Reinhard A. et al., 2018/03. The American journal of gastroenterology, 113 (3) pp. 348-357. Peer-reviewed.
Heterotopic Gastric Mucosa in a Duplication Cyst of the Common Hepatic Duct Mimicking Cholangiocarcinoma.
Sciarra A., Hessler R., Godat S., Fraga M., Dromain C., Duran R., Halkic N., Sempoux C., 2018/02. International journal of surgical pathology, 26 (1) pp. 84-88. Peer-reviewed.
Rapid Remission of Graves' Hyperthyroidism Without Thionamides Under Immunosuppressive Treatment for Concomitant Autoimmune Hepatitis.
Papadakis G.E., Lamine F., Chtioui H., Moschouri E., Christinet M.F., Marino L., Favre L., Sciarra A., Sempoux C., Schneider A. et al., 2018/02. Thyroid, 28 (2) pp. 276-278. Peer-reviewed.
A case of unusual histiocytic colitis in a chronic alcoholic obese patient with ankylosing spondylitis.
Guerra Diaz N., Sempoux C., Jouret-Mourin A., de Burbure C., Druez P., 2018. Acta gastro-enterologica Belgica, 81 (2) pp. 327-329. Peer-reviewed.
Autoimmune Gastritis in the Pediatric Age: An Underestimated Condition Report of Two Cases and Review.
Saglietti C., Sciarra A., Abdelrahman K., Schneider V., Karpate A., Nydegger A., Sempoux C., 2018. Frontiers in pediatrics, 6 p. 123. Peer-reviewed.
Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration.
Ciccarelli O., Colson A., De Saeger C., Reding R., Sempoux C., Leclercq I.A., Stärkel P., 2018. OncoTargets and therapy, 11 pp. 7143-7153. Peer-reviewed.
AMPK activation caused by reduced liver lactate metabolism protects against hepatic steatosis in MCT1 haploinsufficient mice.
Carneiro L., Asrih M., Repond C., Sempoux C., Stehle J.C., Leloup C., Jornayvaz F.R., Pellerin L., 2017/12. Molecular metabolism, 6 (12) pp. 1625-1633. Peer-reviewed.
Focal β-catenin mutation identified on formalin-fixed and paraffin-embedded inflammatory hepatocellular adenomas.
Saldarriaga J., Bisig B., Couchy G., Castain C., Zucman-Rossi J., Balabaud C., Sempoux C., Bioulac-Sage P., 2017/12. Histopathology, 71 (6) pp. 989-993. Peer-reviewed.
Liver and systemic hemodynamics in children with cirrhosis: Impact on the surgical management in pediatric living donor liver transplantation.
de Magnée C., Veyckemans F., Pirotte T., Menten R., Dumitriu D., Clapuyt P., Carbonez K., Barrea C., Sluysmans T., Sempoux C. et al., 2017/11. Liver transplantation, 23 (11) pp. 1440-1450. Peer-reviewed.
Are we done with the immunohistochemical classification of hepatocellular adenoma? [1618]
Raymond AA, Le Bail B., Paradis V., Ferrell L., Sciarra A., Yeh MM, Clouston AD, Miller G., Sempoux C., Quaglia A. et al., 2017/10/31., 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting pp. 865A-866A dans Hepatology.
Reduced hepatocyte uptake of Gd-EOB-DTPA in chronic liver disease is not related to lowered expression of hepatocyte transporters: a radio-pathologic study [625]
Sciarra A., Schmidt S., Daire JL, Leporq B., Van Beers B., Pastor CM, Sempoux C., 2017/10/31., 68th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting pp. 340A-341A dans Hepathology.
06: Visualization of hepatitis E virus RNA and proteins in the human liver
Lenggenhager D, Gouttenoire J., Malehmir M., Bawohl M., Honcharova -Biletska H., Kreutzer S., Semela D., Neuweiler J., Hürlimann S., Aepli P. et al., 2017/10/20. pp. 571-572 dans Swiss Pathology Days, Der Pathologe.
Sterilization of tumor-positive lymph nodes of esophageal cancer by neo-adjuvant treatment is associated with worse survival compared to tumor-negative lymph nodes treated with surgery first.
Mantziari S., Allemann P., Winiker M., Sempoux C., Demartines N., Schäfer M., 2017/09. Journal of surgical oncology, 116 (4) pp. 524-532. Peer-reviewed.
Visualization of hepatitis E virus RNA and proteins in the human liver.
Lenggenhager D., Gouttenoire J., Malehmir M., Bawohl M., Honcharova-Biletska H., Kreutzer S., Semela D., Neuweiler J., Hürlimann S., Aepli P. et al., 2017/09. Journal of hepatology, 67 (3) pp. 471-479. Peer-reviewed.
Lésions hépatiques focales bénignes : revue clinique, radiologique et pathologique [Benign focal liver lesions: a clinical, radiological and pathological review]
Abdelrahman K., Schmidt S., Sciarra A., Sempoux C., 2017/08/30. Revue medicale suisse, 13 (572) pp. 1474-1479. Peer-reviewed.
Hepatocellular Adenomas: Morphology and Genomics.
Bioulac-Sage P., Sempoux C., Balabaud C., 2017/06. Gastroenterology clinics of North America, 46 (2) pp. 253-272. Peer-reviewed.
The caspase-3/p120 RasGAP stress-sensing module reduces liver cancer incidence but does not affect overall survival in gamma-irradiated and carcinogen-treated mice.
Vanli G., Sempoux C., Widmann C., 2017/06. Molecular carcinogenesis, 56 (6) pp. 1680-1684. Peer-reviewed.
Toxocarose : une maladie négligée en Suisse ? [Toxocariasis, a neglected disease in Switzerland ?]
Duréault A., Perez Valdes C., Weber L., Ogna A., Sempoux C., Manuel O., Delaloye J., 2017/04/12. Revue medicale suisse, 13 (558) pp. 815-819. Peer-reviewed.
Detection and Viability of Colorectal Liver Metastases After Neoadjuvant Chemotherapy: A Multiparametric PET/CT-MRI Study.
Dunet V., Halkic N., Prior J.O., Anaye A., Meuli R.A., Sempoux C., Denys A., Schmidt S., 2017/04. Clinical nuclear medicine, 42 (4) pp. 258-263. Peer-reviewed.
Malignant transformation of a β-catenin inflammatory adenoma due to an S45 β-catenin-activating mutation present 12 years before.
Sempoux C., Bisig B., Couchy G., Balabaud C., Zucman-Rossi J., Bioulac-Sage P., 2017/04. Human pathology, 62 pp. 122-125. Peer-reviewed.
Hepatocellular adenoma: Classification, variants and clinical relevance.
Bioulac-Sage P., Sempoux C., Balabaud C., 2017/03. Seminars in diagnostic pathology, 34 (2) pp. 112-125. Peer-reviewed.
Validation of the prognostic value of histologic scoring systems in primary sclerosing cholangitis: An international cohort study.
de Vries E.M., de Krijger M., Färkkilä M., Arola J., Schirmacher P., Gotthardt D., Goeppert B., Trivedi P.J., Hirschfield G.M., Ytting H. et al., 2017/03. Hepatology, 65 (3) pp. 907-919. Peer-reviewed.
Variant differentiation patterns in primary liver carcinoma.
Sempoux C., Paradis V., Saxena R., 2017/03. Seminars in diagnostic pathology, 34 (2) pp. 176-182. Peer-reviewed.
Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis.
Bussmann C., Schoepfer A.M., Safroneeva E., Haas N., Godat S., Sempoux C., Simon H.U., Straumann A., 2016/12. Endoscopy, 48 (12) pp. 1069-1075. Peer-reviewed.
A436: Glutamine synthetase immunohistochemical staining patterns correlate with molecular abnormalities of b-catenin pathway in hepatocellular adenoma
Calderaro J., Sempoux C., Rebouissou S., Bisig B., Cappellen D., Le Bail B., Zucman-Rossi J., Balabaud C., Bioulac-Sage P., 2016/11/15. pp. 221A-222A dans 67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Hepatology.
Oral valganciclovir for CMV gastritis.
Saouli A.C., Salvade I., Saldarriaga J., Manuel O., Venetz J.P., Golshayan D., Sempoux C., Pascual M., 2016/09. Clinics and research in hepatology and gastroenterology, 40 (4) pp. e50-1. Peer-reviewed.
Gastroentérite à éosinophiles [Eosinophilic gastrointestinal disorders]
Burgmann K., Brunel C., Sempoux C., Ribi C., Godat S., Moradpour D., Schoepfer A.M., 2016/08/31. Revue medicale suisse, 13 (528) pp. 1430-1433. Peer-reviewed.
Hepatic small vessel neoplasm, a rare infiltrative vascular neoplasm of uncertain malignant potential.
Gill R.M., Buelow B., Mather C., Joseph N.M., Alves V., Brunt E.M., Liu T.C., Makhlouf H., Marginean C., Nalbantoglu I. et al., 2016/08. Human pathology, 54 pp. 143-151. Peer-reviewed.
Traitement curatif du cancer de l'oesophage: consensus multidisciplinaire multicentrique [Curative treatment for esophageal cancer: results of a multidisciplinary consensus]
Allemann P., Mantziari S., Wagner D., Digklia A., Ozsahin E., De Bari B., Dorta G., Godat S., Montserrat F., Sempoux C. et al., 2016/06/15. Revue medicale suisse, 12 (523) pp. 1165-1169. Peer-reviewed.
Relevance of activated hepatic stellate cells in predicting the development of pediatric liver allograft fibrosis.
Venturi C., Reding R., Quinones J.A., Sokal E., Rahier J., Bueno J., Sempoux C., 2016/06. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 22 (6) pp. 822-829. Peer-reviewed.
1638: Different Types Of Glutamine Synthetase Immunostaining in Hepatocellular Adenoma
Bioulac-Sage P., Le Bail B., Castain C., Sempoux C., Balabaud C., 2016. pp. 415A-415A dans 105th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, Modern Pathology. Peer-reviewed.
Expression of Molecular Differentiation Markers Does Not Correlate with Histological Differentiation Grade in Intrahepatic Cholangiocarcinoma.
Demarez C., Hubert C., Sempoux C., Lemaigre F.P., 2016. PloS one, 11 (6) pp. e0157140. Peer-reviewed.
Lymph node ratio and surgical quality are strong prognostic factors of rectal cancer: results from a single referral centre.
Leonard D., Remue C., Abbes Orabi N., van Maanen A., Danse E., Dragean A., Debetancourt D., Humblet Y., Jouret-Mourin A., Maddalena F. et al., 2016. Colorectal Disease, 18 (6) pp. O175-O184. Peer-reviewed.
Peritoneal sampling and histological assessment of therapeutic response in peritoneal metastasis: proposal of the Peritoneal Regression Grading Score (PRGS)
Solass W., Sempoux C., Detlefsen Sönke., Carr NJ, Bibeau Fr., 2016/01/01. Pleura and Peritoneum, 1 (2). Peer-reviewed.
Regorafenib induced severe toxic hepatitis: characterization and discussion.
Sacré A., Lanthier N., Dano H., Aydin S., Leggenhager D., Weber A., Dekairelle A.F., De Cuyper A., Gala J.L., Humblet Y. et al., 2016. Liver International : Official Journal of the International Association For the Study of the Liver, 36 (11) pp. 1590-1594. Peer-reviewed.
Review of the quality of total mesorectal excision does not improve the prediction of outcome.
Demetter P., Jouret-Mourin A., Silversmit G., Vandendael T., Sempoux C., Hoorens A., Nagy N., Cuvelier C., Van Damme N., Penninckx F. et al., 2016. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 18 (9) pp. 883-888. Peer-reviewed.
Escalating incidence of eosinophilic esophagitis in Canton of Vaud, Switzerland, 1993-2013: a population-based study.
Giriens B., Yan P., Safroneeva E., Zwahlen M., Reinhard A., Nydegger A., Vavricka S., Sempoux C., Straumann A., Schoepfer A.M., 2015/12. Allergy, 70 (12) pp. 1633-1639. Peer-reviewed.
Biphenotypic (hepatobiliary) primary liver carcinomas: the work in progress
Brunt EM, Paradis V., Sempoux Christine., Theise ND, 2015/07. Hepatic Oncology, 2 (3) pp. 255-273. Peer-reviewed.
Completeness and registration bias in PROCARE, a Belgian multidisciplinary project on cancer of the rectum with participation on a voluntary basis.
Jegou D., Penninckx F., Vandendael T., Bertrand C., Van Eycken E., PROCARE , 2015. European Journal of Cancer (oxford, England : 1990), 51 (9) pp. 1099-1108. Peer-reviewed.
Cytological diagnosis of pancreatic neuroendocrine neoplasms
Bongiovanni M., Sempoux C., Nobile A., 2015. pp. 43-50 dans La Rosa S., Sessa F. (eds.) Pancreatic neuroendocrine neoplasms chap. 5, Springer.
Extensive profiling of the expression of the indoleamine 2,3-dioxygenase 1 protein in normal and tumoral human tissues.
Théate I., van Baren N., Pilotte L., Moulin P., Larrieu P., Renauld J.C., Hervé C., Gutierrez-Roelens I., Marbaix E., Sempoux C. et al., 2015. Cancer Immunology Research, 3 (2) pp. 161-172. Peer-reviewed.
Hepatocellular adenoma management: Call for shared guidelines and multidisciplinary approach.
Blanc J.F., Frulio N., Chiche L., Sempoux C., Annet L., Hubert C., Gouw A.S., de Jong K.P., Bioulac-Sage P., Balabaud C., 2015. Clinics and Research In Hepatology and Gastroenterology, 39 (2) pp. 180-187.
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Mu X., Español-Suñer R., Mederacke I., Affò S., Manco R., Sempoux C., Lemaigre F.P., Adili A., Yuan D., Weber A. et al., 2015. Journal of Clinical Investigation, 125 (10) pp. 3891-3903. Peer-reviewed.
Hepatocellular nodules expressing markers of hepatocellular adenomas in Budd-Chiari syndrome and other rare hepatic vascular disorders.
Sempoux C., Paradis V., Komuta M., Wee A., Calderaro J., Balabaud C., Quaglia A., Bioulac-Sage P., 2015. Journal of Hepatology, 63 (5) pp. 1173-1180. Peer-reviewed.
Human Insulinomas Show Distinct Patterns of Insulin Secretion In Vitro.
Henquin J.C., Nenquin M., Guiot Y., Rahier J., Sempoux C., 2015. Diabetes, 64 (10) pp. 3543-3553. Peer-reviewed.
Impact of Intraoperative Pancreatoscopy with Intraductal Biopsies on Surgical Management of Intraductal Papillary Mucinous Neoplasm of the Pancreas.
Navez J., Hubert C., Gigot J.F., Borbath I., Annet L., Sempoux C., Lannoy V., Deprez P., Jabbour N., 2015. Journal of the American College of Surgeons, 221 (5) pp. 982-987. Peer-reviewed.
Living Donor Liver Transplantation in Children: Surgical and Immunological Results in 250 Recipients at Université Catholique de Louvain.
Gurevich M., Guy-Viterbo V., Janssen M., Stephenne X., Smets F., Sokal E., Lefebvre C., Balligand J.L., Pirotte T., Veyckemans F. et al., 2015. Annals of Surgery, 262 (6) pp. 1141-1149. Peer-reviewed.
Occult HBV reactivation induced by ibrutinib treatment: a case report.
de Jésus Ngoma P., Kabamba B., Dahlqvist G., Sempoux C., Lanthier N., Shindano T., Van Den Neste E., Horsmans Y., 2015. Acta Gastro-enterologica Belgica, 78 (4) pp. 424-426. Peer-reviewed.
Panitumumab as a radiosensitizing agent in KRAS wild-type locally advanced rectal cancer.
Mardjuadi F.I., Carrasco J., Coche J.C., Sempoux C., Jouret-Mourin A., Scalliet P., Goeminne J.C., Daisne J.F., Delaunoit T., Vuylsteke P. et al., 2015. Targeted Oncology, 10 (3) pp. 375-383. Peer-reviewed.
Pathological responses after angiogenesis or EGFR inhibitors in metastatic colorectal cancer depend on the chemotherapy backbone.
Carrasco J., Gizzi M., Pairet G., Lannoy V., Lefesvre P., Gigot J.F., Hubert C., Jouret-Mourin A., Humblet Y., Canon J.L. et al., 2015. British Journal of Cancer, 113 (9) pp. 1298-1304. Peer-reviewed.
Quantitative contribution of prognosticators to oncologic outcome after rectal cancer resection.
Leonard D., Penninckx F., Laenen A., Kartheuser A., PROCARE , 2015. Diseases of the Colon and Rectum, 58 (6) pp. 566-574. Peer-reviewed.
Scoring the quality of total mesorectal excision for the prediction of cancer-specific outcome.
Leonard D., Penninckx F., Laenen A., Kartheuser A., PROCARE , 2015. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 17 (5) pp. O115-O122. Peer-reviewed.
Solitary extramedullary plasmocytoma of the thyroid: a case report and histological approach to plasma cells infiltrate in the thyroid gland.
Wilmars M.M., Knoops L., Sempoux C., Galant C., Geets X., Poirel H.A., Ameye G., Camboni A., 2015. Acta Clinica Belgica, 70 (2) pp. 133-137. Peer-reviewed.
SOX9 regulates ERBB signalling in pancreatic cancer development.
Grimont A., Pinho A.V., Cowley M.J., Augereau C., Mawson A., Giry-Laterrière M., Van den Steen G., Waddell N., Pajic M., Sempoux C. et al., 2015. Gut, 64 (11) pp. 1790-1799. Peer-reviewed.
Well-differentiated hepatocellular neoplasm of uncertain malignant potential.
Balabaud C., Bioulac-Sage P., Ferrell L., Kakar S., Paradis V., Quaglia A., Sempoux C., Thung S., Zucman-Rossi J., 2015. Human Pathology, 46 (4) pp. 634-635. Peer-reviewed.
Coexistence of inflammatory hepatocellular adenomas with HNF1α-inactivated adenomas: is there an association?
Castain C., Sempoux C., Brunt E.M., Causse O., Heitzmann A., Hernandez-Prera J.C., Le Bail B., Schirmacher P., Thung S.N., Balabaud C. et al., 2014. Histopathology, 64 (6) pp. 890-895. Peer-reviewed.
Dynamics of allograft fibrosis in pediatric liver transplantation.
Venturi C., Sempoux C., Quinones J.A., Bourdeaux C., Hoyos S.P., Sokal E., Reding R., 2014. American Journal of Transplantation, 14 (7) pp. 1648-1656. Peer-reviewed.
Effect of hospital volume on quality of care and outcome after rectal cancer surgery.
Leonard D., Penninckx F., Kartheuser A., Laenen A., Van Eycken E., PROCARE , 2014. British Journal of Surgery, 101 (11) pp. 1475-1482.
Endoplasmic reticulum stress does not contribute to steatohepatitis in obese and insulin-resistant high-fat-diet-fed foz/foz mice.
Legry V., Van Rooyen D.M., Lambert B., Sempoux C., Poekes L., Español-Suñer R., Molendi-Coste O., Horsmans Y., Farrell G.C., Leclercq I.A., 2014. Clinical Science, 127 (7) pp. 507-518. Peer-reviewed.
Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets.
Zhu A.X., Borger D.R., Kim Y., Cosgrove D., Ejaz A., Alexandrescu S., Groeschl R.T., Deshpande V., Lindberg J.M., Ferrone C. et al., 2014. Annals of Surgical Oncology, 21 (12) pp. 3827-3834. Peer-reviewed.
Immunohistochemical pitfalls in the diagnosis of focal nodular hyperplasia and inflammatory hepatocellular adenoma.
Bioulac-Sage P., Sempoux C., Balabaud C., 2014. Clinics and Research In Hepatology and Gastroenterology, 38 (3) pp. 245-249. Peer-reviewed.
Intraductal biliary polypectomy performed with a nasogastroscope.
Druez A., Kim E., Sempoux C., Deprez P., 2014. Endoscopy International Open, 2 (2) pp. E124-E125. Peer-reviewed.
Is 18F-flutemetamol PET/CT able to reveal cardiac amyloidosis?
Lhommel R., Sempoux C., Ivanoiu A., Michaux L., Gerber B., 2014. Clinical Nuclear Medicine, 39 (8) pp. 747-749. Peer-reviewed.
Is minimal, [almost] steroid-free immunosuppression a safe approach in adult liver transplantation? Long-term outcome of a prospective, double blind, placebo-controlled, randomized, investigator-driven study.
Lerut J.P., Pinheiro R.S., Lai Q., Stouffs V., Orlando G., Juri J.M., Ciccarelli O., Sempoux C., Roggen F.M., De Reyck C. et al., 2014. Annals of Surgery, 260 (5) pp. 886-91; discussion 891-2. Peer-reviewed.
Mesenteric inflammatory myofibroblastic tumor: MRI and CT imaging correlated to anatomical pathology.
Kirchgesner T., Danse E., Sempoux C., Annet L., Dragean C., Trefois P., Abbes Orabi N., Kartheuser A., 2014. Jbr-btr : Organe De La Societe Royale Belge De Radiologie (srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (kbvr), 97 (5) pp. 301-302. Peer-reviewed.
Pancreatic neuroendocrine tumour grading on endoscopic ultrasound-guided fine needle aspiration: high reproducibility and inter-observer agreement of the Ki-67 labelling index.
Weynand B., Borbath I., Bernard V., Sempoux C., Gigot J.F., Hubert C., Lannoy V., Deprez P.H., Jouret-Mourin A., 2014. Cytopathology, 25 (6) pp. 389-395. Peer-reviewed.
Pictures of focal nodular hyperplasia and hepatocellular adenomas.
Sempoux C., Balabaud C., Bioulac-Sage P., 2014. World Journal of Hepatology, 6 (8) pp. 580-595. Peer-reviewed.
Regulation of hepatic EAAT-2 glutamate transporter expression in human liver cholestasis.
Najimi M., Stéphenne X., Sempoux C., Sokal E., 2014. World Journal of Gastroenterology, 20 (6) pp. 1554-1564. Peer-reviewed.
Benign hepatocellular nodules: what have we learned using the patho-molecular classification.
Sempoux C., Chang C., Gouw A., Chiche L., Zucman-Rossi J., Balabaud C., Bioulac-Sage P., 2013. Clinics and Research in Hepatology and Gastroenterology, 37 (4) pp. 322-327. Peer-reviewed.
Characterization of β-cell plasticity mechanisms induced in mice by a transient source of exogenous insulin.
Nollevaux M.C., Rahier J., Marchandise J., Thurion P., Godecharles S., Van den Steen G., Jamart J., Sempoux C., Jacquemin P., Guiot Y., 2013. American Journal of Physiology. Endocrinology and Metabolism, 304 (7) pp. E711-E723.
Combination of gemcitabine and cetuximab in patients with advanced cholangiocarcinoma: a phase II study of the Belgian Group of Digestive Oncology.
Borbath I., Ceratti A., Verslype C., Demols A., Delaunoit T., Laurent S., Deleporte A., Vergauwe P., Van Maanen A., Sempoux C. et al., 2013. Annals of Oncology, 24 (11) pp. 2824-2829.
Congenital hyperinsulinism caused by hexokinase I expression or glucokinase-activating mutation in a subset of β-cells.
Henquin J.C., Sempoux C., Marchandise J., Godecharles S., Guiot Y., Nenquin M., Rahier J., 2013. Diabetes, 62 (5) pp. 1689-1696.
Focal Nodular Hyperplasia and Hepatocellular Adenoma around the World Viewed through the Scope of the Immunopathological Classification.
Balabaud C., Al-Rabih W.R., Chen P.J., Evason K., Ferrell L., Hernandez-Prera J.C., Huang S.F., Longerich T., Park Y.N., Quaglia A. et al., 2013. International Journal of Hepatology, 2013 p. 268625.
Histological and immunohistochemical revision of hepatocellular adenomas: a learning experience.
Fonseca S., Hoton D., Dardenne S., Annet L., Hubert C., Godecharles S., Jouret-Mourin A., Reding R., Otte J.B., Rahier J. et al., 2013. International Journal of Hepatology, 2013 p. 398308. Peer-reviewed.
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice.
Lebrun V., Molendi-Coste O., Lanthier N., Sempoux C., Cani P.D., van Rooijen N., Stärkel P., Horsmans Y., Leclercq I.A., 2013. Clinical Science, 125 (11) pp. 501-511.
Need for objective and reproducible criteria in histopathological assessment of total mesorectal excision specimens: lessons from a national improvement project.
Demetter P., Vandendael T., Sempoux C., Ectors N., Cuvelier C.A., Nagy N., Hoorens A., Jouret-Mourin A., PROCARE , 2013. Colorectal Disease, 15 (11) pp. 1351-1358.
Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context.
Bioulac-Sage P., Sempoux C., Possenti L., Frulio N., Laumonier H., Laurent C., Chiche L., Frédéric Blanc J., Saric J., Trillaud H. et al., 2013. International Journal of Hepatology, 2013 p. 253261.
Prevalence of nonalcoholic steatohepatitis among patients with resectable intrahepatic cholangiocarcinoma.
Reddy S.K., Hyder O., Marsh J.W., Sotiropoulos G.C., Paul A., Alexandrescu S., Marques H., Pulitano C., Barroso E., Aldrighetti L. et al., 2013. Journal of Gastrointestinal Surgery, 17 (4) pp. 748-755.
Risk adjusted benchmarking of abdominoperineal excision for rectal adenocarcinoma in the context of the Belgian PROCARE improvement project.
Penninckx F., Fieuws S., Beirens K., Demetter P., Ceelen W., Kartheuser A., Molle G., Van de Stadt J., Vindevoghel K., Van Eycken E. et al., 2013. Gut, 62 (7) pp. 1005-1011. Peer-reviewed.
Sinusoidal obstruction syndrome (SOS) related to chemotherapy for colorectal liver metastases: factors predictive of severe SOS lesions and protective effect of bevacizumab.
Hubert C., Sempoux C., Humblet Y., van den Eynde M., Zech F., Leclercq I., Gigot J.F., 2013. HPB, 15 (11) pp. 858-864.
Commentary: "Cirrhosis or not cirrhosis": should we discontinue the term?
Sempoux C., Rahier J., 2012. Clinics and Research In Hepatology and Gastroenterology, 36 (5) pp. 405-407. Peer-reviewed.
Defunctioning stoma and anastomotic leak rate after total mesorectal excision with coloanal anastomosis in the context of PROCARE.
Beirens K., Penninckx F., PROCARE , 2012. Acta Chirurgica Belgica, 112 (1) pp. 10-14. Peer-reviewed.
Exploring limits for data registration in the context of PROCARE, a quality improvement project on rectal cancer.
Vandendael T., Penninckx F., Bertrand C., Ceelen W., Danse E., Demetter P., Haustermans K., Laurent S., Molle G., Vandestadt J. et al., 2012. Acta Chirurgica Belgica, 112 (1) pp. 15-23. Peer-reviewed.
From interventional radiology to laparoscopic liver resection as complementary strategies in the treatment of hepatic abscess caused by ingested foreign bodies.
Riani E.B., Tancredi I., Sempoux C., Hubert C., Goffette P., Gigots J.F., 2012. Hepato-gastroenterology, 59 (114) pp. 558-560.
Human equilibrative nucleoside transporter 1 (hENT1) expression is a potential predictive tool for response to gemcitabine in patients with advanced cholangiocarcinoma.
Borbath I., Verbrugghe L., Lai R., Gigot J.F., Humblet Y., Piessevaux H., Sempoux C., 2012. European Journal of Cancer, 48 (7) pp. 990-996. Peer-reviewed.
Hypermethylation of the 5' CpG island of the p14ARF flanking exon 1β in human colorectal cancer displaying a restricted pattern of p53 overexpression concomitant with increased MDM2 expression.
Nyiraneza C., Sempoux C., Detry R., Kartheuser A., Dahan K., 2012. Clinical Epigenetics, 4 (1) p. 9.
Impact of steroid-avoidance immunosuppression on long-term outcome after liver transplantation for HCV cirrhosis: the need for well documented long-term follow-up.
Bonaccorsi-Riani E., Sempoux C., Piette N., Julliard O., Kabamba B., Ciccarelli O., Roggen F., De Reyck C., Hassoun Z., Lerut J., 2012. Acta Gastro-enterologica Belgica, 75 (4) pp. 411-418.
Lanreotide treatment of metastatic hepatocellular carcinoma resulting in partial regression and more than 3 years of progression-free survival.
Borbath I., Lhommel R., Guiot Y., Coche E., Sempoux C., 2012. Acta Gastro-enterologica Belgica, 75 (2) pp. 270-273. Peer-reviewed.
Liver transplantation for hepatocellular cancer: UCL experience in 137 adult cirrhotic patients. Alpha-foetoprotein level and locoregional treatment as refined selection criteria.
Ciccarelli O., Lai Q., Goffette P., Finet P., De Reyck C., Roggen F., Sempoux C., Doffagne E., Reding R., Lerut J., 2012. Transplant International, 25 (8) pp. 867-875.
Novel histologic scoring system for long-term allograft fibrosis after liver transplantation in children.
Venturi C., Sempoux C., Bueno J., Ferreres Pinas J.C., Bourdeaux C., Abarca-Quinones J., Rahier J., Reding R., 2012. American Journal of Transplantation, 12 (11) pp. 2986-2996.
Risk adjusted benchmarking of clinical anastomotic leakage rate after total mesorectal excision in the context of an improvement project.
Penninckx F., Beirens K., Fieuws S., Ceelen W., Demetter P., Haustermans K., Van de Stadt J., Vindevoghel K., PROCARE , 2012. Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland, 14 (7) pp. e413-e421. Peer-reviewed.
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia.
Prévot P.P., Simion A., Grimont A., Colletti M., Khalaileh A., Van den Steen G., Sempoux C., Xu X., Roelants V., Hald J. et al., 2012. Gut, 61 (12) pp. 1723-1732.
Unusual DNA mismatch repair-deficient tumors in Lynch syndrome: a report of new cases and review of the literature.
Karamurzin Y., Zeng Z., Stadler Z.K., Zhang L., Ouansafi I., Al-Ahmadie H.A., Sempoux C., Saltz L.B., Soslow R.A., O'Reilly E.M. et al., 2012. Human Pathology, 43 (10) pp. 1677-1687.
A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis.
Raynaud P., Tate J., Callens C., Cordi S., Vandersmissen P., Carpentier R., Sempoux C., Devuyst O., Pierreux C.E., Courtoy P. et al., 2011. Hepatology, 53 (6) pp. 1959-1966. Peer-reviewed.
Acute cellular rejection resulting in sinusoidal obstruction syndrome and ascites postliver transplantation.
Sanei M.H., Schiano T.D., Sempoux C., Fan C., Fiel M.I., 2011. Transplantation, 92 (10) pp. 1152-1158. Peer-reviewed.
Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.
Grimminger P.P., Danenberg P., Dellas K., Arnold D., Rödel C., Machiels J.P., Haustermans K., Debucquoy A., Velenik V., Sempoux C. et al., 2011. Clinical Cancer Research, 17 (10) pp. 3469-3477. Peer-reviewed.
Cholangiolocellular carcinoma: an innocent-looking malignant liver tumor mimicking ductular reaction.
Sempoux C., Fan C., Singh P., Obeidat K., Roayaie S., Schwartz M., Fiel M.I., Thung S.N., 2011. Seminars in Liver Disease, 31 (1) pp. 104-110.
Comparison of different methods to quantify future liver remnants after preoperative portal vein embolization to predict postoperative liver failure.
Shah A., Goffette P., Hubert C., Lerut J., Van Beers B.B., Annet L., Sempoux C., Gigot J.F., 2011. Hepato-gastroenterology, 58 (105) pp. 109-114. Peer-reviewed.
Distinctive patterns of p53 protein expression and microsatellite instability in human colorectal cancer.
Nyiraneza C., Jouret-Mourin A., Kartheuser A., Camby P., Plomteux O., Detry R., Dahan K., Sempoux C., 2011. Human Pathology, 42 (12) pp. 1897-1910. Peer-reviewed.
EGF61 polymorphism predicts complete pathologic response to cetuximab-based chemoradiation independent of KRAS status in locally advanced rectal cancer patients.
Hu-Lieskovan S., Vallbohmer D., Zhang W., Yang D., Pohl A., Labonte M.J., Grimminger P.P., Hölscher A.H., Semrau R., Arnold D. et al., 2011. Clinical Cancer Research, 17 (15) pp. 5161-5169. Peer-reviewed.
Familial adenomatous polyposis: clinical presentation, detection and surveillance.
Laurent S., Franchimont D., Coppens J.P., Leunen K., Macken L., Peeters M., Plomteux O., Polus M., Poppe B., Sempoux C. et al., 2011. Acta Gastro-enterologica Belgica, 74 (3) pp. 415-420. Peer-reviewed.
In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions.
Henquin J.C., Nenquin M., Sempoux C., Guiot Y., Bellanné-Chantelot C., Otonkoski T., de Lonlay P., Nihoul-Fékété C., Rahier J., 2011. Journal of Clinical Investigation, 121 (10) pp. 3932-3942. Peer-reviewed.
Intrahepatic cholangiocarcinoma: new insights in pathology.
Sempoux C., Jibara G., Ward S.C., Fan C., Qin L., Roayaie S., Fiel M.I., Schwartz M., Thung S.N., 2011. Seminars in Liver Disease, 31 (1) pp. 49-60. Peer-reviewed.
Morphologic analysis of focal and diffuse forms of congenital hyperinsulinism.
Rahier J., Guiot Y., Sempoux C., 2011. Seminars in Pediatric Surgery, 20 (1) pp. 3-12.
Morphological mosaicism of the pancreatic islets: a novel anatomopathological form of persistent hyperinsulinemic hypoglycemia of infancy.
Sempoux C., Capito C., Bellanné-Chantelot C., Verkarre V., de Lonlay P., Aigrain Y., Fekete C., Guiot Y., Rahier J., 2011. Journal of Clinical Endocrinology and Metabolism, 96 (12) pp. 3785-3793. Peer-reviewed.
ABCC8 and KCNJ11 molecular spectrum of 109 patients with diazoxide-unresponsive congenital hyperinsulinism.
Bellanné-Chantelot C., Saint-Martin C., Ribeiro M.J., Vaury C., Verkarre V., Arnoux J.B., Valayannopoulos V., Gobrecht S., Sempoux C., Rahier J. et al., 2010. Journal of Medical Genetics, 47 (11) pp. 752-759. Peer-reviewed.
Accurate KRAS mutation testing for EGFR-targeted therapy in colorectal cancer: emphasis on the key role and responsibility of pathologists.
Hoorens A., Jouret-Mourin A., Sempoux C., Demetter P., De Hertogh G., Teugels E., 2010. Acta Gastro-enterologica Belgica, 73 (4) pp. 497-503. Peer-reviewed.
Congenital hyperinsulinism.
Arnoux J.B., de Lonlay P., Ribeiro M.J., Hussain K., Blankenstein O., Mohnike K., Valayannopoulos V., Robert J.J., Rahier J., Sempoux C. et al., 2010. Early Human Development, 86 (5) pp. 287-294. Peer-reviewed.
Conservative and operative management of benign solid hepatic tumours: a successful stratified algorithm.
Dardenne S., Hubert C., Sempoux C., Annet L., Jouret-Mourin A., Horsmans Y., Van Beers B.E., Zech F., Gigot J.F., 2010. European Journal of Gastroenterology and Hepatology, 22 (11) pp. 1337-1344. Peer-reviewed.
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats.
Borbath I., Leclercq I.A., Sempoux C., Abarca-Quinones J., Desaeger C., Horsmans Y., 2010. Chemico-biological Interactions, 183 (1) pp. 238-248. Peer-reviewed.
Endoplasmic reticulum accumulation of Kir6.2 without activation of ER stress response in islet cells from adult Sur1 knockout mice.
Marhfour I., Jonas J.C., Marchandise J., Lefevre A., Rahier J., Sempoux C., Guiot Y., 2010. Cell and Tissue Research, 340 (2) pp. 335-346. Peer-reviewed.
Endoscopic mucosal or submucosal resection of early neoplasia in Barrett's esophagus after antireflux surgery.
Van Den Eynde M., Jouret-Mourin A., Sempoux C., Piessevaux H., Deprez P.H., 2010. Gastrointestinal Endoscopy, 72 (4) pp. 855-861. Peer-reviewed.
Factors predicting the quality of total mesorectal excision for rectal cancer.
Leonard D., Penninckx F., Fieuws S., Jouret-Mourin A., Sempoux C., Jehaes C., Van Eycken E., PROCARE a multidisciplinary Belgian Project on Cancer of the Rectum, 2010. Annals of Surgery, 252 (6) pp. 982-988. Peer-reviewed.
High risk for neoplastic transformation of endometriosis in a carrier of Lynch syndrome.
Nyiraneza C., Marbaix E., Smets M., Galant C., Sempoux C., Dahan K., 2010. Familial Cancer, 9 (3) pp. 383-387. Peer-reviewed.
Large spectrum of liver vascular lesions including high prevalence of focal nodular hyperplasia in patients with hereditary haemorrhagic telangiectasia: the Belgian Registry based on 30 patients.
Brenard R., Chapaux X., Deltenre P., Henrion J., De Maeght S., Horsmans Y., Borbath I., Leenaerts A., Van Cauter J., Francque S. et al., 2010. European Journal of Gastroenterology and Hepatology, 22 (10) pp. 1253-1259.
Liver transplantation and neuroendocrine tumors: lessons from a single centre experience and from the literature review.
Bonaccorsi-Riani E., Apestegui C., Jouret-Mourin A., Sempoux C., Goffette P., Ciccarelli O., Borbath I., Hubert C., Gigot J.F., Hassoun Z. et al., 2010. Transplant International, 23 (7) pp. 668-678. Peer-reviewed.
MRI of iron-oxide labelled transplanted hepatocytes in mice: effect of treatment with cyclophosphamide.
Leconte I., Pallu S., Abarca-Quinones J., Michoux N., Peeters F., Radermacher K., Sempoux C., Najimi M., Sokal E., Van Beers B.E., 2010. Journal of Magnetic Resonance Imaging, 32 (2) pp. 367-375. Peer-reviewed.
Prevalence and clinical relevance of pathological hepatic changes occurring after neoadjuvant chemotherapy for colorectal liver metastases.
Hubert C., Fervaille C., Sempoux C., Horsmans Y., Humblet Y., Machiels J.P., Zech F., Ceratti A., Gigot J.F., 2010. Surgery, 147 (2) pp. 185-194. Peer-reviewed.
Successful long-term management of a patient with late-stage metastatic colorectal cancer treated with panitumumab.
Seront E., Marot L., Coche E., Gala J.L., Sempoux C., Humblet Y., 2010. Cancer Treatment Reviews, 36 (Suppl 1) pp. S11-S14. Peer-reviewed.
Vascular reconstruction during pancreatoduodenectomy for ductal adenocarcinoma of the pancreas improves resectability but does not achieve cure.
Ouaissi M., Hubert C., Verhelst R., Astarci P., Sempoux C., Jouret-Mourin A., Loundou A., Gigot J.F., Multidisciplary HPB Group of Center of Cancer, 2010. World Journal of Surgery, 34 (11) pp. 2648-2661. Peer-reviewed.
A kernel-based integration of genome-wide data for clinical decision support.
Daemen A., Gevaert O., Ojeda F., Debucquoy A., Suykens J.A., Sempoux C., Machiels J.P., Haustermans K., De Moor B., 2009. Genome Medicine, 1 (4) p. 39. Peer-reviewed.
Autoimmune pancreatitis, sclerosing cholangitis, liver inflammatory pseudotumors, retroperitoneal fibrosis, lymphadenopathy, and sialoadenitis in a single patient: a multifaceted expression of a hitherto unrecognized systemic autoimmune syndrome?
de Suray N., Van Beers B., Sempoux C., Borschette C., Lonneux M., Deprez P., Geubel A., 2009. Pancreas, 38 (4) pp. 476-478.
CT underestimation of ileo-colic ischemia: a case report with pathologic correlation.
Thiery C., Sempoux C., Danse E., 2009. Jbr-btr : Organe de la Société Royale Belge de Radiologie (srbr) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (kbvr), 92 (4) pp. 213-217. Peer-reviewed.
Impact of Sur1 gene inactivation on the morphology of mouse pancreatic endocrine tissue.
Marhfour I., Moulin P., Marchandise J., Rahier J., Sempoux C., Guiot Y., 2009. Cell and Tissue Research, 335 (3) pp. 505-515.
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer.
Debucquoy A., Haustermans K., Daemen A., Aydin S., Libbrecht L., Gevaert O., De Moor B., Tejpar S., McBride W.H., Penninckx F. et al., 2009. Journal of Clinical Oncology, 27 (17) pp. 2751-2757. Peer-reviewed.
Rare presentation of familial paraganglioma without evidence of mutation in the SDH, RET and VHL genes: towards further genetic heterogeneity.
Persu A., Amyere M., Gutierrez-Roelens I., Rustin P., Sempoux C., Lecouvet F.E., Van Beers B.E., Horsmans Y., De Plaen J.F., MarcHamoir M. et al., 2009. Journal of Hypertension, 27 (1) pp. 76-82. Peer-reviewed.
Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury.
Van Hul N.K., Abarca-Quinones J., Sempoux C., Horsmans Y., Leclercq I.A., 2009. Hepatology, 49 (5) pp. 1625-1635. Peer-reviewed.
Ulcerative colitis associated with IgG4 cholangitis: similar features in two HLA identical siblings.
Dastis S.N., Latinne D., Sempoux C., Geubel A.P., 2009. Journal of Hepatology, 51 (3) pp. 601-605. Peer-reviewed.
Une mastocytose inhabituelle.. [An unusual mastocytosis...].
Bafort D., Sempoux C., Bohon P., Theate I., Jouret-Mourin A., 2009. Annales de Pathologie, 29 (5) pp. 440-442. Peer-reviewed.
Une tumeur duodénale inhabituelle [An uncommon duodenal tumor].
Ho Minh Duc D.K., Sempoux C., Theate I., Collard J.M., Jouret-Mourin A., 2009. Annales de Pathologie, 29 (5) pp. 432-434.
Usefulness of histopathological markers in diagnosing Barrett's intraepithelial neoplasia (dysplasia).
Jouret-Mourin A., Sempoux C., Duc K.H., Geboes K., 2009. Acta Gastro-enterologica Belgica, 72 (4) pp. 425-432. Peer-reviewed.
Acute hepatitis with prolonged cholestasis and disappearance of interlobular bile ducts following tibolone and Hypericum perforatum (St. John's wort). Case of drug interaction?
Etogo-Asse F., Boemer F., Sempoux C., Geubel A., 2008. Acta Gastro-enterologica Belgica, 71 (1) pp. 36-38. Peer-reviewed.
Magnetic resonance elastography for the noninvasive staging of liver fibrosis.
Huwart L., Sempoux C., Vicaut E., Salameh N., Annet L., Danse E., Peeters F., ter Beek L.C., Rahier J., Sinkus R. et al., 2008. Gastroenterology, 135 (1) pp. 32-40. Peer-reviewed.
Pancreatic beta-cell mass in European subjects with type 2 diabetes.
Rahier J., Guiot Y., Goebbels R.M., Sempoux C., Henquin J.C., 2008. Diabetes, Obesity and Metabolism, 10 (Suppl 4) pp. 32-42. Peer-reviewed.
Stepwise radical endoscopic resection for Barrett's esophagus with early neoplasia: report on a Brussels' cohort.
Pouw R.E., Peters F.P., Sempoux C., Piessevaux H., Deprez P.H., 2008. Endoscopy, 40 (11) pp. 892-898. Peer-reviewed.
Tacrolimus monotherapy in liver transplantation: one-year results of a prospective, randomized, double-blind, placebo-controlled study.
Lerut J., Mathys J., Verbaandert C., Talpe S., Ciccarelli O., Lemaire J., Bonaccorsi-Riani E., Vanthuyne V., Hetsch N., Roggen F. et al., 2008. Annals of Surgery, 248 (6) pp. 956-967.
Adult-derived human liver mesenchymal-like cells as a potential progenitor reservoir of hepatocytes?
Najimi M., Khuu D.N., Lysy P.A., Jazouli N., Abarca J., Sempoux C., Sokal E.M., 2007. Cell Transplantation, 16 (7) pp. 717-728. Peer-reviewed.
Benign biliary inflammatory pseudotumor mimicking a Klatskin tumor.
Gohy S., Hubert C., Deprez P., Van Beers B.E., Annet L., Lhommel R., Sempoux C., Jean-François G., 2007. Hepato-gastroenterology, 54 (77) pp. 1348-1352. Peer-reviewed.
Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide.
Borbath I., Leclercq I.A., Abarca-Quinones J., Desaeger C., Lebrun V., Moulin P., Sempoux C., Horsmans Y., 2007. Cancer Science, 98 (12) pp. 1831-1839. Peer-reviewed.
Liver fibrosis: noninvasive assessment with MR elastography versus aspartate aminotransferase-to-platelet ratio index.
Huwart L., Sempoux C., Salameh N., Jamart J., Annet L., Sinkus R., Peeters F., ter Beek L.C., Horsmans Y., Van Beers B.E., 2007. Radiology, 245 (2) pp. 458-466. Peer-reviewed.
Morphological localisation of sulfonylurea receptor 1 in endocrine cells of human, mouse and rat pancreas.
Guiot Y., Stevens M., Marhfour I., Stiernet P., Mikhailov M., Ashcroft S.J., Rahier J., Henquin J.C., Sempoux C., 2007. Diabetologia, 50 (9) pp. 1889-1899. Peer-reviewed.
Nodular regenerative hyperplasia: a deleterious consequence of chemotherapy for colorectal liver metastases?
Hubert C., Sempoux C., Horsmans Y., Rahier J., Humblet Y., Machiels J.P., Ceratti A., Canon J.L., Gigot J.F., 2007. Liver International : Official Journal of the International Association For the Study of the Liver, 27 (7) pp. 938-943. Peer-reviewed.
Percutaneous and surgical radiofrequency ablation of liver malignancies: a single institutional experience.
Hubert C., Gras J., Goffette P., Grajeda J.M., Van Beers B.E., Laurence A., Horsmans Y., Sempoux C., Rahier J., Zech F. et al., 2007. Acta Gastro-enterologica Belgica, 70 (2) pp. 188-194. Peer-reviewed.
Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer.
Machiels J.P., Sempoux C., Scalliet P., Coche J.C., Humblet Y., Van Cutsem E., Kerger J., Canon J.L., Peeters M., Aydin S. et al., 2007. Annals of Oncology : Official Journal of the European Society For Medical Oncology, 18 (4) pp. 738-744. Peer-reviewed.
Prognostic risk factors of survival after resection of hepatocellular carcinoma.
Hubert C., Sempoux C., Rahier J., Horsmans Y., Geubel A., Van Beers B.E., Annet L., Zech F., Leonard D., Gigot J.F., 2007. Hepato-gastroenterology, 54 (78) pp. 1791-1797. Peer-reviewed.
The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver.
Borbath I., Leclercq I., Moulin P., Sempoux C., Horsmans Y., 2007. European Journal of Cancer (oxford, England : 1990), 43 (11) pp. 1755-1763. Peer-reviewed.
Hepatogastroenterologist and pathologist: a winning team ... for good patient management
Jouret Anne, Geubel A. P., Sempoux Christine, 2006/06. Acta Endoscopica, 36 (3) pp. I-III.
Non-alcoholic fatty liver disease: from steatosis to cirrhosis. [Hépatopathie non alcoolique: de la stéatose à la cirrhose]
Leclercq I., Sempoux C., 2006/06. Acta Endoscopica, 36 (3) pp. 299-314. Peer-reviewed.
Congenital hyperinsulinism and mosaic abnormalities of the ploidy.
Giurgea I., Sanlaville D., Fournet J.C., Sempoux C., Bellanné-Chantelot C., Touati G., Hubert L., Groos M.S., Brunelle F., Rahier J. et al., 2006. Journal of Medical Genetics, 43 (3) pp. 248-254. Peer-reviewed.
Defective hepatic regeneration after partial hepatectomy in leptin-deficient mice is not rescued by exogenous leptin.
Leclercq I.A., Vansteenberghe M., Lebrun V.B., VanHul N.K., Abarca-Quinones J., Sempoux C.L., Picard C., Stärkel P., Horsmans Y.L., 2006. Laboratory Investigation; A Journal of Technical Methods and Pathology, 86 (11) pp. 1161-1171. Peer-reviewed.
Hypervitaminosis A-induced liver fibrosis: stellate cell activation and daily dose consumption.
Nollevaux M.C., Guiot Y., Horsmans Y., Leclercq I., Rahier J., Geubel A.P., Sempoux C., 2006. Liver International : Official Journal of the International Association For the Study of the Liver, 26 (2) pp. 182-186. Peer-reviewed.
Limited therapeutic efficacy of pioglitazone on progression of hepatic fibrosis in rats.
Leclercq I.A., Sempoux C., Stärkel P., Horsmans Y., 2006. Gut, 55 (7) pp. 1020-1029. Peer-reviewed.
Long-term survival after isolated liver transplantation for intrahepatic biliary papillomatosis.
Charre L., Boillot O., Goffette P., Geubel A., Gigot J.F., Sempoux C., Lerut J., 2006. Transplant International : Official Journal of the European Society For Organ Transplantation, 19 (3) pp. 249-252. Peer-reviewed.
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