Aurélien Thomas

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127 publications

SMYD3: a new regulator of the early steps of adipocyte differentiation
Gilardi Federica, Sajic Tatjana, Gasser Marie, Caputo Tiziana, Bararpour Nasim, Augsburger Marc, Walter Nadia, Hainard Alexander, Fracasso Tony, Thomas Aurelien.
SMYD3: a new regulator of adipocyte precursor proliferation at the early steps of differentiation.
Sajic T., Ferreira Gomes C.K., Gasser M., Caputo T., Bararpour N., Landaluce-Iturriria E., Augsburger M., Walter N., Hainard A., Lopez-Mejia I.C. et al., 2024/04. International journal of obesity, 48 (4) pp. 557-566. Peer-reviewed.
 
Effects of personal exposure to the oxidative potential of PM2.5 on oxidative stress biomarkers in pregnant women.
Marsal A., Sauvain J.J., Thomas A., Lyon-Caen S., Borlaza LJS, Philippat C., Jaffrezo J.L., Boudier A., Darfeuil S., Elazzouzi R. et al., 2024/02/10. The Science of the total environment, 911 p. 168475. Peer-reviewed.
 
Gonadotropin axis and semen quality in young Swiss men after cannabis consumption: Effect of chronicity and modulation by cannabidiol.
Zufferey F., Buitrago E., Rahban R., Senn A., Stettler E., Rudaz S., Nef S., Donzé N., Thomas A., Rossier M.F., 2024/01. Andrology, 12 (1) pp. 56-67. Peer-reviewed.
People living with HIV display increased anti-apolipoprotein A1 auto-antibodies, inflammation, and kynurenine metabolites: a case-control study.
Frias M.A., Pagano S., Bararpour N., Sidibé J., Kamau F., Fétaud-Lapierre V., Hudson P., Thomas A., Lecour S., Strijdom H. et al., 2024. Frontiers in cardiovascular medicine, 11 p. 1343361. Peer-reviewed.
Cannabis use and atherosclerotic cardiovascular disease: a Mendelian randomization study.
de La Harpe R., Schoeler T., Thorball C.W., Thomas A., Kutalik Z., Vaucher J., 2023/12/13. BMC cardiovascular disorders, 23 (1) p. 611. Peer-reviewed.
Arsenic induces metabolome remodeling in mature human adipocytes.
Gasser M., Lenglet S., Bararpour N., Sajic T., Vaucher J., Wiskott K., Augsburger M., Fracasso T., Gilardi F., Thomas A., 2023/12. Toxicology, 500 p. 153672. Peer-reviewed.
 
La médecine légale à Genève
Grabherr Silke, Fauvel Aude, Sabatasso Sara, Castella Vincent, Thomas Aurélien, Wiskott Kim, Fracasso Tony, 2023/10/11. Revue Médicale Suisse, 19 (845-2) pp. 1870-1873.
Association of Trace Element Levels with Outcomes in Critically Ill COVID-19 Patients.
Wozniak H., Le Terrier C., Primmaz S., Suh N., Lenglet S., Thomas A., Vuilleumier N., Pagano S., de Watteville A., Stringhini S. et al., 2023/07/26. Nutrients, 15 (15) p. 3308. Peer-reviewed.
Differentiating individuals through the chemical composition of their fingermarks.
Gorka M., Thomas A., Bécue A., 2023/05. Forensic science international, 346 p. 111645. Peer-reviewed.
 
Comparison of Dried Blood Spot and Microtube Techniques for Trace Element Quantification by ICP-MS.
Perrais M., Thomas A., Augsburger M., Lenglet S., 2023/03/21. Journal of analytical toxicology, 47 (2) pp. 175-181. Peer-reviewed.
Blood proteome of acute intracranial hemorrhage in infant victims of abusive head trauma.
Wiskott K., Gilardi F., Hainard A., Sanchez J.C., Thomas A., Sajic T., Fracasso T., 2023/02. Proteomics, 23 (3-4) pp. e2200078. Peer-reviewed.
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone.
Nunes C., Proença S., Ambrosini G., Pamies D., Thomas A., Kramer N.I., Zurich M.G., 2023. Frontiers in pharmacology, 14 p. 1248882. Peer-reviewed.
Randomly controlled drivers using minimally invasive sampling: assessment of drug prevalence in Western Switzerland over two time periods.
Joye T., Déglon J., Donzé N., Gilardi F., Sidibé J., Favrat B., Augsburger M., Thomas A., 2022/12/28. BMC public health, 22 (1) p. 2446. Peer-reviewed.
PhenoExplorer: An Interactive Web-based Platform for Exploring (Epi)Genome-Wide Associations Using a Swiss Population-based Study.
Ghobril J.P., Petrovic D., Ehret G., Ponte B., Pruijm M., Ackermann D., Vogt B., Stringhini S., Thomas A., Chamberlain J. et al., 2022/12/21. Chimia, 76 (12) pp. 1052-1062. Peer-reviewed.
Chemical composition of the fingermark residue: Assessment of the intravariability over one year using MALDI-MSI.
Gorka M., Thomas A., Bécue A., 2022/09. Forensic science international, 338 p. 111380. Peer-reviewed.
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.
Nunes C., Singh P., Mazidi Z., Murphy C., Bourguignon A., Wellens S., Chandrasekaran V., Ghosh S., Zana M., Pamies D. et al., 2022/06. Toxicology in vitro, 81 p. 105333. Peer-reviewed.
Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots.
Magliocco G., Desmeules J., Samer C.F., Thomas A., Daali Y., 2022/06. Clinical and translational science, 15 (6) pp. 1482-1491. Peer-reviewed.
 
Toxicity and Metabolomic Impact of Cobalt, Chromium, and Nickel Exposure on HepaRG Hepatocytes.
Bellouard M., Gasser M., Lenglet S., Gilardi F., Bararpour N., Augsburger M., Thomas A., Alvarez J.C., 2022/05/16. Chemical research in toxicology, 35 (5) pp. 807-816. Peer-reviewed.
 
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity.
Sblano S., Cerchia C., Laghezza A., Piemontese L., Brunetti L., Leuci R., Gilardi F., Thomas A., Genovese M., Santi A. et al., 2022/05/05. European journal of medicinal chemistry, 235 p. 114240. Peer-reviewed.
Creation of a Forensic Pathology Biobank in Switzerland: which issues and research opportunities?
Wiskott K., Gilardi F., Michaud K., Augsburger M., Castiglioni C., Carminati A., Grabherr S., Thomas A., Fracasso T., 2022/05. International journal of legal medicine, 136 (3) pp. 919-922. Peer-reviewed.
Cadmium acute exposure induces metabolic and transcriptomic perturbations in human mature adipocytes.
Gasser M., Lenglet S., Bararpour N., Sajic T., Wiskott K., Augsburger M., Fracasso T., Gilardi F., Thomas A., 2022/03/30. Toxicology, 470 p. 153153. Peer-reviewed.
Analyse systématique du GHB dans les échantillons biologiques : rapport de synthèse 2021
Augsburger M., Thomas A., Carron PN, 2022/01/01. 21, Unité de toxicologie et de chimie forensiques, Centre universitaire romand de médecine légale.
The Allelic Variant A391T of Metal Ion Transporter ZIP8 (SLC39A8) Leads to Hypotension and Enhanced Insulin Resistance.
Verouti S.N., Pujol-Giménez J., Bermudez-Lekerika P., Scherler L., Bhardwaj R., Thomas A., Lenglet S., Siegrist M., Hofstetter W., Fuster D.G. et al., 2022. Frontiers in physiology, 13 p. 912277. Peer-reviewed.
Development of a printed quality control test strip for the analysis and imaging of fingermark composition.
Gorka M., Thomas A., Bécue A., 2021/12. Forensic science international, 329 p. 111063. Peer-reviewed.
Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity.
Magliocco G., Desmeules J., Matthey A., Quirós-Guerrero L.M., Bararpour N., Joye T., Marcourt L., Queiroz E.F., Wolfender J.L., Gloor Y. et al., 2021/12. British journal of pharmacology, 178 (23) pp. 4708-4725. Peer-reviewed.
Suspicion of driving under the influence of alcohol or drugs: Cross sectional analysis of drug prevalence in the context of the Swiss legislation.
Maurer J., Vergalito E., Prior A.F., Donzé N., Thomas A., Augsburger M., 2021/12. Forensic science international, 329 p. 111081. Peer-reviewed.
Metabolomic alteration induced by psychotropic drugs: Short-term metabolite profile as a predictor of weight gain evolution.
Lenski M., Sidibé J., Gholam M., Hennart B., Dubath C., Augsburger M., von Gunten A., Conus P., Allorge D., Thomas A. et al., 2021/11. Clinical and translational science, 14 (6) pp. 2544-2555. Peer-reviewed.
Simultaneous determination of melatonin and 6-hydroxymelatonin in human overnight urine by LC-MS/MS.
Magliocco G., Le Bloc'h F., Thomas A., Desmeules J., Daali Y., 2021/09/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1181 p. 122938. Peer-reviewed.
Summary statistics for drugs and alcohol concentration recovered in post-mortem femoral blood in Western Switzerland.
Lefrancois E., Reymond N., Thomas A., Lardi C., Fracasso T., Augsburger M., 2021/08. Forensic science international, 325 p. 110883. Peer-reviewed.
Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects.
Nacher-Soler G., Lenglet S., Coelho M., Thomas A., Voruz F., Krause K.H., Senn P., Rousset F., 2021/07/31. Frontiers in cellular neuroscience, 15 p. 701783. Peer-reviewed.
A single session of moderate intensity exercise influences memory, endocannabinoids and brain derived neurotrophic factor levels in men.
Marin Bosch B., Bringard A., Logrieco M.G., Lauer E., Imobersteg N., Thomas A., Ferretti G., Schwartz S., Igloi K., 2021/07/13. Scientific reports, 11 (1) p. 14371. Peer-reviewed.
Enantiomeric methadone quantitation on real post-mortem dried matrix spots samples: Comparison of liquid chromatography and supercritical fluid chromatography coupled to mass spectrometry.
Mueller F., Losacco G.L., Nicoli R., Guillarme D., Thomas A., Grata E., 2021/07/01. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1177 p. 122755. Peer-reviewed.
Triangulating evidence from longitudinal and Mendelian randomization studies of metabolomic biomarkers for type 2 diabetes.
Porcu E., Gilardi F., Darrous L., Yengo L., Bararpour N., Gasser M., Marques-Vidal P., Froguel P., Waeber G., Thomas A. et al., 2021/03/18. Scientific reports, 11 (1) p. 6197. Peer-reviewed.
DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies.
Bararpour N., Gilardi F., Carmeli C., Sidibe J., Ivanisevic J., Caputo T., Augsburger M., Grabherr S., Desvergne B., Guex N. et al., 2021/03/11. Scientific reports, 11 (1) p. 5657. Peer-reviewed.
Detecting early myocardial ischemia in rat heart by MALDI imaging mass spectrometry.
Aljakna Khan A., Bararpour N., Gorka M., Joye T., Morel S., Montessuit C.A., Grabherr S., Fracasso T., Augsburger M., Kwak B.R. et al., 2021/03/04. Scientific reports, 11 (1) p. 5135. Peer-reviewed.
Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland.
Mueller F., Bogdal C., Pfeiffer B., Andrello L., Ceschi A., Thomas A., Grata E., 2021/03. Forensic science international, 320 p. 110686. Peer-reviewed.
Sphingosine-1-phosphate as a key player of insulin secretion induced by high-density lipoprotein treatment.
Brulhart-Meynet M.C., Thomas A., Sidibé J., Visentin F., Dusaulcy R., Schwitzgebel V., Pataky Z., Philippe J., Vuilleumier N., James R.W. et al., 2021/03. Physiological reports, 9 (6) pp. e14786. Peer-reviewed.
The 1β-Hydroxy-Deoxycholic Acid to Deoxycholic Acid Urinary Metabolic Ratio: Toward a Phenotyping of CYP3A Using an Endogenous Marker?
Magliocco G., Desmeules J., Bosilkovska M., Thomas A., Daali Y., 2021/02/20. Journal of personalized medicine, 11 (2) p. 150. Peer-reviewed.
Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue.
Caputo T., Tran VDT, Bararpour N., Winkler C., Aguileta G., Trang KB, Giordano Attianese GMP, Wilson A., Thomas A., Pagni M. et al., 2021/01. Cellular and molecular life sciences, 78 (1) pp. 227-247. Peer-reviewed.
Vascular-targeted micelles as a specific MRI contrast agent for molecular imaging of fibrin clots and cancer cells.
Vorobiev V., Adriouach S., Crowe L.A., Lenglet S., Thomas A., Chauvin A.S., Allémann E., 2021/01. European journal of pharmaceutics and biopharmaceutics, 158 pp. 347-358. Peer-reviewed.
Identification of metabolomics biomarkers for type 2 diabetes: triangulating evidence from longitudinal and Mendelian randomization analyses
Porcu E., Gilardi F., Darrous L., Yengo L., Bararpour N., Gasser M., Vidal PM, Froguel P., Waeber G., Thomas A. et al., 2020/10/30..
Effect of acute physical exercise on motor sequence memory.
Marin Bosch B., Bringard A., Logrieco MG, Lauer E., Imobersteg N., Thomas A., Ferretti G., Schwartz S., Igloi K., 2020/09/18. Scientific reports, 10 (1) p. 15322. Peer-reviewed.
Driving Under the Influence of Drugs: A Single Parallel Monitoring-Based Quantification Approach on Whole Blood.
Joye T., Rocher K., Déglon J., Sidibé J., Favrat B., Augsburger M., Thomas A., 2020/08/26. Frontiers in chemistry, 8 p. 626. Peer-reviewed.
High-Throughput Qualitative and Quantitative Drug Checking by MALDI HRMS.
Joye T., Widmer C., Morger Mégevand R., Longère S., Augsburger M., Thomas A., 2020/08/25. Frontiers in chemistry, 8 p. 695. Peer-reviewed.
Parallel Reaction Monitoring-Based Quantification of Cannabinoids in Whole Blood.
Joye T., Widmer C., Favrat B., Augsburger M., Thomas A., 2020/07/31. Journal of analytical toxicology, 44 (6) pp. 541-548. Peer-reviewed.
 
Renal handling of zinc in chronic kidney disease patients and the role of circulating zinc levels in renal function decline.
Damianaki K., Lourenco JM, Braconnier P., Ghobril JP, Devuyst O., Burnier M., Lenglet S., Augsburger M., Thomas A., Pruijm M., 2020/07/01. Nephrology, dialysis, transplantation, 35 (7) pp. 1163-1170. Peer-reviewed.
Ambulatory Blood Pressure in Relation to Plasma and Urinary Manganese.
Zhang ZY, Carmeli C., Ponte B., Pruijm M., Ackermann D., Ehret G., Guessous I., Petrović D., Pechère-Bertschi A., Vogt B. et al., 2020/04. Hypertension, 75 (4) pp. 1133-1139. Peer-reviewed.
Visualization and normalization of drift effect across batches in metabolome-wide association studies
Bararpour N., Gilardi F., Carmeli C., Sidibe J., Ivanisevic J., Caputo T., Augsburger M., Grabherr S., Desvergne B., Guex N. et al., 2020/01/22..
 
Phenotyping of Human CYP450 Enzymes by Endobiotics: Current Knowledge and Methodological Approaches.
Magliocco G., Thomas A., Desmeules J., Daali Y., 2019/11. Clinical pharmacokinetics, 58 (11) pp. 1373-1391. Peer-reviewed.
 
Pharmacokinetics and biodistribution study of self-assembled Gd-micelles demonstrating blood-pool contrast enhancement for MRI.
Vorobiev V., Babič A., Crowe L.A., Van De Looij Y., Lenglet S., Thomas A., Helm L., Vallée J.P., Allémann E., 2019/09/10. International journal of pharmaceutics, 568 p. 118496. Peer-reviewed.
Liquid chromatography-high resolution mass spectrometry for broad-spectrum drug screening of dried blood spot as microsampling procedure.
Joye T., Sidibé J., Déglon J., Karmime A., Sporkert F., Widmer C., Favrat B., Lescuyer P., Augsburger M., Thomas A., 2019/07/31. Analytica chimica acta, 1063 pp. 110-116. Peer-reviewed.
2-Arachidonoylglycerol mobilizes myeloid cells and worsens heart function after acute myocardial infarction.
Schloss M.J., Horckmans M., Guillamat-Prats R., Hering D., Lauer E., Lenglet S., Weber C., Thomas A., Steffens S., 2019/03/01. Cardiovascular research, 115 (3) pp. 602-613. Peer-reviewed.
 
In situ metabolomic changes in rat hippocampus after acute cocaine administration
Joye T., Bararpour N., Augsburger M., Boutrel B., Thomas A., 2019/03. International Journal of Mass Spectrometry, 437 pp. 87-91. Peer-reviewed.
 
Molecular composition of fingermarks: Assessment of the intra- and inter-variability in a small group of donors using MALDI-MSI
Gorka M., Augsburger Marc., Thomas A., Bécue A., 2019/03. Forensic Chemistry, 12 pp. 99-106. Peer-reviewed.
 
Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner.
Guillamat Prats R., Rami M., Ring L., Rinne P., Lauer E., Lenglet S., Thomas A., Pagano S., Vuilleumier N., Cravatt B.F. et al., 2019/02. Thrombosis and haemostasis, 119 (2) pp. 348-351. Peer-reviewed.
Iron is neurotoxic in retinal detachment and transferrin confers neuroprotection.
Daruich A., Le Rouzic Q., Jonet L., Naud M.C., Kowalczuk L., Pournaras J.A., Boatright J.H., Thomas A., Turck N., Moulin A. et al., 2019/01. Science advances, 5 (1) pp. eaau9940. Peer-reviewed.
 
Multiplex quantitative imaging of human myocardial infarction by mass spectrometry-immunohistochemistry.
Aljakna A., Lauer E., Lenglet S., Grabherr S., Fracasso T., Augsburger M., Sabatasso S., Thomas A., 2018/11. International journal of legal medicine, 132 (6) pp. 1675-1684. Peer-reviewed.
Separation of blood microsamples by exploiting sedimentation at the microscale.
Forchelet D., Béguin S., Sajic T., Bararpour N., Pataky Z., Frias M., Grabherr S., Augsburger M., Liu Y., Charnley M. et al., 2018/09/20. Scientific reports, 8 (1) p. 14101. Peer-reviewed.
 
XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules.
Domingo-Almenara X., Montenegro-Burke J.R., Ivanisevic J., Thomas A., Sidibé J., Teav T., Guijas C., Aisporna A.E., Rinehart D., Hoang L. et al., 2018/09. Nature methods, 15 (9) pp. 681-684. Peer-reviewed.
 
Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.
Storelli F., Matthey A., Lenglet S., Thomas A., Desmeules J., Daali Y., 2018/07. Clinical pharmacology and therapeutics, 104 (1) pp. 148-157. Peer-reviewed.
 
Analyse du phosphatidyléthanol sur micro-prélèvement de sang séché : nouvel outil pour le suivi de la consommation d'alcool
Déglon J., Lauer E., Sporkert F., Valois N., Favrat B., Thomas A., Augsburger M., 2018/06. pp. S42-S43 dans 26e Congrès annuel de la Société Française de Toxicologie Analytique Marseille, 5-8 juin 2018, Toxicologie analytique et clinique, Elsevier BV.
 
Cannabis légal riche en CBD et cannabis illicite riche en THC en Suisse, peut-on différencier leur consommation dans le sang et l'urine ?
Augsburger M., Sporkert F., Varlet V., Widmer C., Déglon J., Thomas A., 2018/06. pp. S21-S22 dans Toxicologie Analytique et Clinique, Elsevier BV.
 
Développement et intérêt de l'approche ciblée pour l'analyse métabolomique
Sidibé J., Gallart Ayala H., Augsburger M., Ivanisevic J., Thomas A., 2018/06. pp. S31-S32 dans Toxicologie Analytique et Clinique, Elsevier BV.
 
Métabolomique et autres omiques en toxicologie : approches, applications et défis
Thomas A., 2018/06. pp. S30 dans Toxicologie Analytique et Clinique, Elsevier BV.
 
Trace element intakes should be revisited in burn nutrition protocols: A cohort study.
Jafari P., Thomas A., Haselbach D., Watfa W., Pantet O., Michetti M., Raffoul W., Applegate L.A., Augsburger M., Berger M.M., 2018/06. Clinical nutrition, 37 (3) pp. 958-964. Peer-reviewed.
 
Évaluation du prélèvement de sang sur papier buvard analysé par UHPLC-HRMS pour le criblage large échelle de drogues et de médicaments
Joye T., Sidibe J., Déglon J., Karmime A., Sporkert F., Favrat B., Lescuyer P., Augsburger M., Thomas A., 2018/06. pp. S79-S80 dans Toxicologie Analytique et Clinique, Elsevier BV.
 
High-density lipoprotein from end-stage renal disease patients exhibits superior cardioprotection and increase in sphingosine-1-phosphate.
Brinck J.W., Thomas A., Brulhart-Meynet M.C., Lauer E., Frej C., Dahlbäck B., Stenvinkel P., James R.W., Frias M.A., 2018/02. European journal of clinical investigation, 48 (2) pp. 1-7. Peer-reviewed.
Beneficial Effects of Human Mesenchymal Stromal Cells on Porcine Hepatocyte Viability and Albumin Secretion.
Montanari E., Pimenta J., Szabó L., Noverraz F., Passemard S., Meier RPH, Meyer J., Sidibe J., Thomas A., Schuurman H.J. et al., 2018. Journal of immunology research, 2018 p. 1078547. Peer-reviewed.
Effects of a Weight Loss Program on Metabolic Syndrome, Eating Disorders and Psychological Outcomes: Mediation by Endocannabinoids?
Pataky Z., Carrard I., Gay V., Thomas A., Carpentier A., Bobbioni-Harsch E., Golay A., 2018. Obesity facts, 11 (2) pp. 144-156. Peer-reviewed.
 
Metabolomics as a Tool to Understand Pathophysiological Processes
Ivanisevic Julijana, Thomas Aurelien, 2018. pp. 3-28 dans Clinical Metabolomics chap. 1, Springer New York.
Proteome and Metabolome of Subretinal Fluid in Central Serous Chorioretinopathy and Rhegmatogenous Retinal Detachment: A Pilot Case Study.
Kowalczuk L., Matet A., Dor M., Bararpour N., Daruich A., Dirani A., Behar-Cohen F., Thomas A., Turck N., 2018/01. Translational vision science & technology, 7 (1) p. 3. Peer-reviewed.
Will Widespread Synthetic Opioid Consumption Induce Epigenetic Consequences in Future Generations?
Gilardi F., Augsburger M., Thomas A., 2018. Frontiers in pharmacology, 9 p. 702. Peer-reviewed.
In vivo neurochemical measurements in cerebral tissues using a droplet-based monitoring system.
Petit-Pierre G., Colin P., Laurer E., Déglon J., Bertsch A., Thomas A., Schneider B.L., Renaud P., 2017/11/01. Nature communications, 8 (1) p. 1239. Peer-reviewed.
 
PoB-35: The 2-arachidonoylglyercol/cannabinoid receptor 2 axis regulates bone marrow mobilization and myeloid cell recruitment after myocardial infarction
Horckmans M., Schloss M., Bianchini M., Megens R., Ring L., Thomas A., Lauer E., Lenglet S., Weber C., Duchene J. et al., 2017/10/11., 2nd Joint Meeting of the European-Society-for-Microcirculation (ESM) and European-Vascular-Biology-Organisation (EVBO) pp. 59-59 dans Journal of Vascular Research.
 
Acute physical exercise improves memory consolidation in humans via BDNF and endocannabinoid signaling
Marin Bosch B, Bringard A, Logrieco MG, Lauer E, Imobersteg NM, Ferretti G, Thomas A, Schwartz S, Igloi K, 2017/10..
 
4789: Transcriptome and metabolome analysis in patients with retinitis pigmentosa caused by mutations in pre-mRNA splicing factor genes
Balzano S., Prunotto A., Thomas A., Rivolta C., 2017/09/30., Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO) pp. - dans Investigative Ophthalmology and Visual Science.
 
Un cas peu commun d'intoxication sous-cutanée par le mercure métallique (Hg 0 ) liquide
Augsburger M., Thomas A., Vollenweider P., 2017/05. pp. S39 dans Toxicologie Analytique et Clinique, Elsevier BV.
 
Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function.
Quercioli A., Carbone F., Bonaventura A., Liberale L., Pataky Z., Thomas A., Lenglet S., Lauer E., Golay A., Dallegri F. et al., 2017/03/15. International journal of cardiology, 231 pp. 1-5. Peer-reviewed.
 
High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia.
Frias M.A., Thomas A., Brulhart-Meynet M.C., Kövamees O., Pernow J., Eriksson M., Angelin B., James R.W., Brinck J.W., 2017/01. European journal of clinical investigation, 47 (1) pp. 38-43. Peer-reviewed.
 
Omics in Forensic Toxicology a Bridge Towards Forensic Medicine
Bararpour Nasim, Sporkert Frank, Augsburger Marc, Thomas Aurélien, 2017., Springer International Publishing.
A systematic review of passive exposure to cannabis
Berthet Aurélie, De Cesare Mariangela, Favrat Bernard, Sporkert Frank, Augsburger Marc, Thomas Aurélien, Giroud Christian, 2016/12. Forensic Science International, 269 pp. 97-112. Peer-reviewed.
Assessment of pathological response to therapy using lipid mass spectrometry imaging.
Patterson N.H., Alabdulkarim B., Lazaris A., Thomas A., Marcinkiewicz M.M., Gao Z.H., Vermeulen P.B., Chaurand P., Metrakos P., 2016/11/14. Scientific reports, 6 p. 36814. Peer-reviewed.
 
Imaging mass spectrometry of elements in forensic cases by LA-ICP-MS.
Lauer E., Villa M., Jotterand M., Vilarino R., Bollmann M., Michaud K., Grabherr S., Augsburger M., Thomas A., 2016/08/10. International journal of legal medicine pp. 1-4. Peer-reviewed.
 
A1: Validation of the Geneva cocktail for cytochrome P450 phenotyping using innovative dried blood sampling method
Bosilkovska M., Samer C.F., Deglon J., Thomas A., Desmeules J.A., Daali Y., 2016/07/15. pp. 21-22 dans 20th North American Meeting of the International-Society-for-the-Study-of-Xenobiotics, Drug Metabolism Reviews.
Drug vaping applied to cannabis: Is "Cannavaping" a therapeutic alternative to marijuana?
Varlet V., Concha-Lozano Nicolas, Berthet Aurélie, Plateel Gregory, Favrat B., De Cesare M., Lauer E., Augsburger M., Thomas A., Giroud C., 2016/05/26. Scientific Reports, 6 p. 25599. Peer-reviewed.
 
(MA)LDI MS Imaging at High Specificity and Sensitivity
Thomas A., Heath Patterson N., Dufresne M., Chaurand P., 2016. pp. 129-147 dans Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry, Springer.
 
Diabetes Mellitus Is Associated With Reduced High-Density Lipoprotein Sphingosine-1-Phosphate Content and Impaired High-Density Lipoprotein Cardiac Cell Protection.
Brinck J.W., Thomas A., Lauer E., Jornayvaz F.R., Brulhart-Meynet M.C., Prost J.C., Pataky Z., Löfgren P., Hoffstedt J., Eriksson M. et al., 2016. Arteriosclerosis, Thrombosis, and Vascular Biology, 36 (5) pp. 817-824. Peer-reviewed.
 
E-cigarette and cannabis: assessment of passive exposure
Berthet Aurélie, De Cesare Mariangela, Varlet Vincent, Favrat Bernard, Giroud Christian, Augsburger Marc, Concha-Lozano Nicolas, Thomas Aurélien, 2016. p. 564 dans 55th Annual Meeting and ToxExpo, March 13-17, 2016, New Orleans, Louisiana, The Toxicologist : an official publication of the Society of Toxicology. Peer-reviewed.
 
Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method.
Bosilkovska M., Samer C., Déglon J., Thomas A., Walder B., Desmeules J., Daali Y., 2016. Basic and Clinical Pharmacology and Toxicology, 119 (3) pp. 284-290. Peer-reviewed.
 
GOP-10: Post-mortem diagnosis of myocardial ischemia. A feasibility study on the application of LA-ICP MS, with multiplex quantitative imaging
Sabatasso S., Lauer E., Fracasso T., Lenglet S., Villa M., Augsburger M., Thomas A., 2016. dans IALM intersocietal symposium. Peer-reviewed.
 
O40: Cannavaping : vapotage récréatif de stupéfiants ou nouveau mode d'administration de médicaments?
Varlet Vincent, Concha-Lozano Nicolas, Berthet Aurélie, Thomas Aurélien, Augsburger Marc, Giroud Christian, 2016. pp. S30-S31 dans 24e Congrès annuel de la Société Française de Toxicologie Analytique, Toxicologie analytique et clinique. Peer-reviewed.
 
Systematic evaluation of matrix effects in hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry.
Periat A., Kohler I., Thomas A., Nicoli R., Boccard J., Veuthey J.L., Schappler J., Guillarme D., 2016. Journal of Chromatography. A, 1439 pp. 42-53. Peer-reviewed.
 
Three-dimensional imaging MS of lipids in atherosclerotic plaques: Open-source methods for reconstruction and analysis.
Patterson N.H., Doonan R.J., Daskalopoulou S.S., Dufresne M., Lenglet S., Montecucco F., Thomas A., Chaurand P., 2016. Proteomics, 16 (11-12) pp. 1642-1651. Peer-reviewed.
 
Current approaches and challenges for the metabolite profiling of complex natural extracts.
Wolfender J.L., Marti G., Thomas A., Bertrand S., 2015. Journal of Chromatography. A, 1382C pp. 136-164. Peer-reviewed.
 
Gastric bypass in morbid obese patients is associated with reduction in adipose tissue inflammation via N-oleoylethanolamide (OEA)-mediated pathways.
Montecucco F., Lenglet S., Quercioli A., Burger F., Thomas A., Lauer E., da Silva A.R., Mach F., Vuilleumier N., Bobbioni-Harsch E. et al., 2015. Thrombosis and Haemostasis, 113 (4) pp. 838-850. Peer-reviewed.
Improving Reconstituted HDL Composition for Efficient Post-Ischemic Reduction of Ischemia Reperfusion Injury.
Brulhart-Meynet M.C., Braunersreuther V., Brinck J., Montecucco F., Prost J.C., Thomas A., Galan K., Pelli G., Pedretti S., Vuilleumier N. et al., 2015. Plos One, 10 (3) pp. e0119664. Peer-reviewed.
 
New microfluidic-based sampling procedure for overcoming the hematocrit problem associated with dried blood spot analysis.
Leuthold L.A., Heudi O., Déglon J., Raccuglia M., Augsburger M., Picard F., Kretz O., Thomas A., 2015. Analytical Chemistry, 87 (4) pp. 2068-2071. Peer-reviewed.
 
Potential missing steps for a wide use of dried matrix spots in biomedical analysis
Deglon J., Leuthold LA, Thomas A., 2015. Bioanalysis, 7 (18) pp. 2375-2385. Peer-reviewed.
Toxicity assessment of refill liquids for electronic cigarettes.
Varlet V., Farsalinos K., Augsburger M., Thomas A., Etter J.F., 2015. International Journal of Environmental Research and Public Health, 12 (5) pp. 4796-4815. Peer-reviewed.
 
Advances in tissue section preparation for MALDI imaging MS
Thomas A., Chaurand P., 2014. Bioanalysis, 6 (7) pp. 967-982.
 
Monitoring time-dependent degradation of phospholipids in sectioned tissues by MALDI imaging mass spectrometry.
Patterson NH, Thomas A., Chaurand P., 2014. Journal of Mass Spectrometry, 49 (7) pp. 622-627.
 
Endogenous cannabinoid receptor CB1 activation promotes vascular smooth-muscle cell proliferation and neointima formation.
Molica F., Burger F., Thomas A., Staub C., Tailleux A., Staels B., Pelli G., Zimmer A., Cravatt B., Matter C.M. et al., 2013/05. Journal of lipid research, 54 (5) pp. 1360-1368. Peer-reviewed.
 
Fatty acid amide hydrolase deficiency enhances intraplaque neutrophil recruitment in atherosclerotic mice.
Lenglet S., Thomas A., Soehnlein O., Montecucco F., Burger F., Pelli G., Galan K., Cravatt B., Staub C., Steffens S., 2013. Arteriosclerosis, Thrombosis, and Vascular Biology, 33 (2) pp. 215-223.
 
Histology-driven data mining of lipid signatures from multiple imaging mass spectrometry analyses: application to human colorectal cancer liver metastasis biopsies.
Thomas A., Patterson N.H., Marcinkiewicz M.M., Lazaris A., Metrakos P., Chaurand P., 2013. Analytical Chemistry, 85 (5) pp. 2860-2866.
 
Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines.
Quercioli A., Montecucco F., Pataky Z., Thomas A., Ambrosio G., Staub C., Di Marzo V., Ratib O., Mach F., Golay A. et al., 2013. European Heart Journal, 34 (27) pp. 2063-2073.
 
Orthogonal organic and aqueous-based washes of tissue sections to enhance protein sensitivity by MALDI imaging mass spectrometry.
Thomas A., Patterson N.H., Laveaux Charbonneau J., Chaurand P., 2013. Journal of Mass Spectrometry, 48 (1) pp. 42-48.
 
Silver-assisted laser desorption ionization for high spatial resolution imaging mass spectrometry of olefins from thin tissue sections.
Dufresne M., Thomas A., Breault-Turcot J., Masson J.F., Chaurand P., 2013. Analytical Chemistry, 85 (6) pp. 3318-3324.
Weed or wheel! FMRI, behavioural, and toxicological investigations of how cannabis smoking affects skills necessary for driving.
Battistella G., Fornari E., Thomas A., Mall J.F., Chtioui H., Appenzeller M., Annoni J.M., Favrat B., Maeder P., Giroud C., 2013/01. Plos One, 8 (1) pp. e52545. Peer-reviewed.
 
Coronary vasomotor control in obesity and morbid obesity: contrasting flow responses with endocannabinoids, leptin, and inflammation.
Quercioli A., Pataky Z., Montecucco F., Carballo S., Thomas A., Staub C., Di Marzo V., Vincenti G., Ambrosio G., Ratib O. et al., 2012. Jacc. Cardiovascular Imaging, 5 (8) pp. 805-815. Peer-reviewed.
 
Direct analysis of dried blood spots coupled with mass spectrometry: concepts and biomedical applications.
Déglon J., Thomas A., Mangin P., Staub C., 2012. Analytical and Bioanalytical Chemistry, 402 (8) pp. 2485-2498.
 
Molecular imaging of matrix metalloproteinases in atherosclerotic plaques.
Lenglet S., Thomas A., Chaurand P., Galan K., Mach F., Montecucco F., 2012. Thrombosis and Haemostasis, 107 (3) pp. 409-416.
 
Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot.
Daali Y., Samer C., Déglon J., Thomas A., Chabert J., Rebsamen M., Staub C., Dayer P., Desmeules J., 2012. Clinical Pharmacology and Therapeutics, 91 (3) pp. 489-496. Peer-reviewed.
 
Rapid LC-MS/MS quantification of the major benzodiazepines and their metabolites on dried blood spots using a simple and cost-effective sample pretreatment.
Déglon J., Versace F., Lauer E., Widmer C., Mangin P., Thomas A., Staub C., 2012. Bioanalysis, 4 (11) pp. 1337-1350.
 
Receptor activator of NF-κB ligand (RANKL) increases the release of neutrophil products associated with coronary vulnerability
Bertolotto Maria, Lenglet Sébastien, Vuilleumier Nicolas, Galan Katia, Pagano Sabrina, Braunersreuther Vincent, Pelli Graziano, Pistoia Vito, Bianchi Giovanna, Cittadini Giuseppe et al., 2012. Thrombosis and Haemostasis, 107 (01) pp. 124-139.
 
Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition.
Thomas A., Charbonneau J.L., Fournaise E., Chaurand P., 2012. Analytical Chemistry, 84 (4) pp. 2048-2054.
 
O72 Les concentrations plasmatiques d'endocannabinoid sont associées avec une dysfonction de la microcirculation coronarienne chez les sujets obèses
Quercioli A., Pataky Z., Vincenti G., Montecucco F., Thomas A., Staub C., Di Marzo V., Seimbille Y., Ratib O., Mach F. et al., 2011/03. pp. A18 dans Diabetes & Metabolism, Elsevier BV.
 
Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite.
Déglon J., Thomas A., Daali Y., Lauer E., Samer C., Desmeules J., Dayer P., Mangin P., Staub C., 2011. Journal of Pharmaceutical and Biomedical Analysis, 54 (2) pp. 359-367.
 
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity.
Quercioli A., Pataky Z., Vincenti G., Makoundou V., Di Marzo V., Montecucco F., Carballo S., Thomas A., Staub C., Steffens S. et al., 2011. European Heart Journal, 32 (11) pp. 1369-1378. Peer-reviewed.
 
Mass spectrometry for the evaluation of cardiovascular diseases based on proteomics and lipidomics.
Thomas A., Lenglet S., Chaurand P., Deglon J., Mangin P., Mach F., Steffens S., Wolfender J.L., Staub C., 2011. Thrombosis and Haemostasis, 106 (1) pp. 20-33.
 
High-throughput phospholipidic fingerprinting by online desorption of dried spots and quadrupole-linear ion trap mass spectrometry: evaluation of atherosclerosis biomarkers in mouse plasma.
Thomas A., Déglon J., Lenglet S., Mach F., Mangin P., Wolfender J.L., Steffens S., Staub C., 2010. Analytical Chemistry, 82 (15) pp. 6687-6694.
 
On-line desorption of dried blood spots coupled to hydrophilic interaction/reversed-phase LC/MS/MS system for the simultaneous analysis of drugs and their polar metabolites.
Thomas A., Déglon J., Steimer T., Mangin P., Daali Y., Staub C., 2010. Journal of Separation Science, 33 (6-7) pp. 873-879. Peer-reviewed.
 
Use of the dried blood spot sampling process coupled with fast gas chromatography and negative-ion chemical ionization tandem mass spectrometry: application to fluoxetine, norfluoxetine, reboxetine, and paroxetine analysis.
Déglon J., Lauer E., Thomas A., Mangin P., Staub C., 2010. pp. 2523-2532 dans 47th Annual Meeting of the International-Association-of-Forensic-Toxicologists, Analytical and bioanalytical chemistry.
 
On-line desorption of dried blood spot: A novel approach for the direct LC/MS analysis of micro-whole blood samples.
Déglon J., Thomas A., Cataldo A., Mangin P., Staub C., 2009. Journal of pharmaceutical and biomedical analysis, 49 (4) pp. 1034-9.
 
Quantitative and qualitative profiling of endocannabinoids in human plasma using a triple quadrupole linear ion trap mass spectrometer with liquid chromatography.
Thomas A., Hopfgartner G., Giroud C., Staub C., 2009. Rapid Communications in Mass spectrometry, 23 (5) pp. 629-638. Peer-reviewed.
 
Consommation de cannabis : quels sont les risques ?
Giroud C, Bollmann M., Thomas A., Mangin P., Favrat B., 2008/11. Annales de toxicologie analytique, 20 (4) pp. 183-205.
 
Fast gas chromatography and negative-ion chemical ionization tandem mass spectrometry for forensic analysis of cannabinoids in whole blood.
Thomas A., Widmer C., Hopfgartner G., Staub C., 2007. Journal of Pharmaceutical and Biomedical Analysis, 45 (3) pp. 495-503. Peer-reviewed.
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