Niels Lion

Publications | Phd and Masters theses

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66 publications

2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 |
2018
Proteomics of Stored Red Blood Cell Membrane and Storage-Induced Microvesicles Reveals the Association of Flotillin-2 With Band 3 Complexes
Prudent Michel, Delobel Julien, Hübner Aurélie, Benay Corinne, Lion Niels, Tissot Jean-Daniel, 2018/05/04. Frontiers in Physiology, 9 p. 421. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_6B99B17A9073]
2017
Redox Proteomics and Platelet Activation: Understanding the Redox Proteome to Improve Platelet Quality for Transfusion.
Sonego G., Abonnenc M., Tissot J.D., Prudent M., Lion N., 2017/04/11. International journal of molecular sciences, 18 (2) pp. E387.
[URN][DOI][WoS][Pmid][serval:BIB_33AFE8220365]
2016
 
Antioxidant power as a quality control marker for completeness of amotosalen and ultraviolet A photochemical treatments in platelet concentrates and plasma units.
Abonnenc M., Crettaz D., Tacchini P., Di Vincenzo L., Sonego G., Prudent M., Tissot J.D., Lion N., 2016. Transfusion, 56 (7) pp. 1819-1827. Peer-reviewed.
[DOI][Pmid][serval:BIB_2E25EC6CEDEC]
 
Cysteine redox proteomics of the hemoglobin-depleted cytosolic fraction of stored red blood cells.
Delobel J., Prudent M., Crettaz D., ElHajj Z., Riederer B.M., Tissot J.D., Lion N., 2016. Proteomics. Clinical Applications, 10 (8) pp. 883-893. Peer-reviewed.
[DOI][Pmid][serval:BIB_676B09538E85]
 
Hepcidin as a new biomarker for detecting autologous blood transfusion.
Leuenberger N., Barras L., Nicoli R., Robinson N., Baume N., Lion N., Barelli S., Tissot J.D., Saugy M., 2016. American Journal of Hematology, 91 (5) pp. 467-472. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2DDE07BF29A7]
 
Is proteomics still knockin' on the hematological door?
Lion N., Tissot J.D., Prudent M., 2016. Proteomics. Clinical Applications, 10 (8) pp. 765-766. Peer-reviewed.
[DOI][Pmid][serval:BIB_549909ED346C]
Sensitive and fast identification of bacteria in blood samples by immunoaffinity mass spectrometry for quick BSI diagnosis
Zhu Y.D., Qiao L., Prudent M., Bondarenko A., Gasilova N., Moller S.B., Lion N., Pick H., Gong T.Q., Chen Z.X. et al., 2016. Chemical Science, 7 (5) pp. 2897-2995.
[URN][DOI][WoS][serval:BIB_6EC8C68163D6]
Small-Scale Perfusion Bioreactor of Red Blood Cells for Dynamic Studies of Cellular Pathways: Proof-of-Concept.
Prudent M., Stauber F., Rapin A., Hallen S., Pham N., Abonnenc M., Marvin L., Rochat B., Tissot J.D., Lion N., 2016. Frontiers In Molecular Biosciences, 3 p. 11. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_3E886A2EF6FC]
 
Urinary di-(2-ethylhexyl) phthalate metabolites for detecting transfusion of autologous blood stored in plasticizer-free bags.
Leuenberger N., Barras L., Nicoli R., Robinson N., Baume N., Lion N., Barelli S., Tissot J.D., Saugy M., 2016. Transfusion, 56 (3) pp. 571-578. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_61E3BEE13EE8]
2015
 
In vitro assays and clinical trials in red blood cell aging: Lost in translation.
Prudent M., Tissot J.D., Lion N., 2015. Transfusion and Apheresis Science, 52 (3) pp. 270-276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_99F4B95DA25F]
 
In vitro evaluation of pathogen-inactivated buffy coat-derived platelet concentrates during storage: psoralen-based photochemical treatment step-by-step.
Abonnenc M., Sonego G., Kaiser-Guignard J., Crettaz D., Prudent M., Tissot J.D., Lion N., 2015. Blood Transfusion = Trasfusione Del Sangue, 13 (2) pp. 255-264. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DAAC2563D037]
2014
 
Large scale inkjet-printing of carbon nanotubes electrodes for antioxidant assays in blood bags
Lesch Andreas, Cortés-Salazar Fernando, Prudent Michel, Delobel Julien, Rastgar Shokoufeh, Lion Niels, Tissot Jean-Daniel, Tacchini Philippe, Girault Hubert H., 2014. Journal of Electroanalytical Chemistry, 717-718 pp. 61-68. Peer-reviewed.
[DOI][WoS][serval:BIB_95B3B54940B1]
 
LC-MS/MS analysis and comparison of oxidative damages on peptides induced by pathogen reduction technologies for platelets.
Prudent M., Sonego G., Abonnenc M., Tissot J.D., Lion N., 2014. Journal of the American Society For Mass Spectrometry, 25 (4) pp. 651-661. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_373E7BA7910C]
 
Proteome changes in platelets after pathogen inactivation--an interlaboratory consensus.
Prudent M., D'Alessandro A., Cazenave J.P., Devine D.V., Gachet C., Greinacher A., Lion N., Schubert P., Steil L., Thiele T. et al., 2014. Transfusion Medicine Reviews, 28 (2) pp. 72-83. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_7737F742544F]
The clinical and biological impact of new pathogen inactivation technologies on platelet concentrates.
Kaiser-Guignard J., Canellini G., Lion N., Abonnenc M., Osselaer J.C., Tissot J.D., 2014. Blood Reviews, 28 (6) pp. 235-241. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0DF65F1D66D1]
 
The picture of Dorian Gray: news from the red blood cell storage lesion.
Tissot J.D., Lion N., 2014. Blood Transfusion = Trasfusione Del Sangue, 12 (3) pp. 293-295.
[URN][DOI][WoS][Pmid][serval:BIB_67C59040D93C]
2013
 
Blood microvesicles: from proteomics to physiology
Tissot J.D., Canellini G., Rubin O., Angelillo-Scherrer A., Delobel J., Prudent M., Lion N., 2013. Translational Proteomics, 1 (1) pp. 38-52.
[URN][DOI][serval:BIB_ED95246059FD]
 
Detecting Microparticles in Blood Components-A Potential Solution
Labrie A., Leung J., Crettaz D., Prudent M., Lion N., Maurer-Spurej E., 2013. pp. 87 A dans AABB Annual Meeting and CTTXPO, Transfusion. Peer-reviewed.
[WoS][serval:BIB_E757B641416A]
 
Dual-channel electrospray microchip.
Lu Y., Liu F., Lion N., Girault H.H., 2013. Journal of the American Society For Mass Spectrometry, 24 (3) pp. 454-457. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_47D721D1BD20]
 
Myths: history, blood, sex and money.
Tissot J.D., Lion N., 2013. Blood Transfusion = Trasfusione del Sangue, 11 (1) pp. 1-3.
[DOI][WoS][Pmid][serval:BIB_B74BA0BAFDDE]
 
Red blood cell-derived microparticles isolated from blood units initiate and propagate thrombin generation.
Rubin O., Delobel J., Prudent M., Lion N., Kohl K., Tucker E.I., Tissot J.D., Angelillo-Scherrer A., 2013. Transfusion, 53 (8) pp. 1744-1754.
[DOI][WoS][Pmid][serval:BIB_EC8284C97B27]
2012
 
Aggregation and proteomic analyses of intercept-treated platelets
Prudent M., Crettaz D., Guignard J., Delobel J., Tissot J.D., Lion N., 2012. pp. 63A dans AABB Annual Meeting and CTTXPO, Transfusion.
[WoS][serval:BIB_A80C87E26518]
 
Microparticles from stored red blood cells induce thrombin generation
Rubin O., Lion N., Angelillo-Scherrer A., Tiisot J.D., 2012. pp. 144-145 dans 32nd International Congress of the International Society of Blood Transfusion in joint cooperation with the 10th Congress of AMMTAC, Vox Sanguinis.
[WoS][serval:BIB_3649F0099B13]
 
Proteomic analysis of Intercept-treated platelets.
Prudent M., Crettaz D., Delobel J., Tissot J.D., Lion N., 2012. Journal of Proteomics, 76 (Spec. Is.) pp. 316-328. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AB49B111883F]
 
Quantitation and identification of carbonylated proteins in subcellular fractions of stored red blood cells
Delobel J., Prudent M., Crettaz D., Tissot J.D., Lion N., 2012. pp. 82A dans AABB Annual Meeting and CTTXPO, Transfusion.
[WoS][serval:BIB_CB44AA28FFF6]
 
Red blood cell microparticles and blood group antigens: an analysis by flow cytometry.
Canellini G., Rubin O., Delobel J., Crettaz D., Lion N., Tissot J.D., 2012. Blood Transfusion = Trasfusione del Sangue, 10 (Suppl. 2) pp. s39-s45. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5B528AEF2F10]
 
Red blood cell microparticles: clinical relevance.
Rubin O., Canellini G., Delobel J., Lion N., Tissot J.D., 2012. Transfusion Medicine and Hemotherapy, 39 (5) pp. 342-347. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_360F3966ED26]
 
Subcellular fractionation of stored red blood cells reveals a compartment-based protein carbonylation evolution.
Delobel J., Prudent M., Rubin O., Crettaz D., Tissot J.D., Lion N., 2012. Journal of Proteomics, 76 (Spec No.) pp. 181-193. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_08071938706F]
 
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
Fauvet B., Mbefo M.K., Fares M.B., Desobry C., Michael S., Ardah M.T., Tsika E., Coune P., Prudent M., Lion N. et al., 2012. Journal of Biological Chemistry, 287 (19) pp. 15345-15364. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7ECFB935DE20]
2011
 
Proteomics of blood and derived products: what's next?
Prudent M., Tissot J.D., Lion N., 2011. Expert Review of Proteomics, 8 (6) pp. 717-737.
[DOI][WoS][Pmid][serval:BIB_29709D6182F9]
 
Protéomique et médecine transfusionnelle [Proteomics and transfusion medicine].
Lion N., Prudent M., Crettaz D., Tissot J.D., 2011. Transfusion Clinique et Biologique, 18 (2) pp. 79-96.
[DOI][WoS][Pmid][serval:BIB_52975F604046]
2010
Biomarker analysis of stored blood products: emphasis on pre-analytical issues.
Delobel J., Rubin O., Prudent M., Crettaz D., Tissot J.D., Lion N., 2010. International Journal of Molecular Sciences, 11 (11) pp. 4601-4617.
[URN][DOI][WoS][Pmid][serval:BIB_AADFD6BAE81D]
 
Electrochemical reactions and ionization processes.
Girault H., Liu B., Qiao L., Bi H., Prudent M., Lion N., Abonnenc M., 2010. European Journal of Mass Spectrometry, 16 (3) pp. 341-349. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_50C8605FB2D5]
 
Microparticles in stored red blood cells: submicron clotting bombs?
Rubin O., Crettaz D., Tissot J.D., Lion N., 2010. Blood Transfusion = Trasfusione Del Sangue, 8 Suppl 3 pp. s31-s38.
[DOI][WoS][Pmid][serval:BIB_F40723B327D6]
 
Pre-analytical and methodological challenges in red blood cell microparticle proteomics.
Rubin O., Crettaz D., Tissot J.D., Lion N., 2010. Talanta, 82 (1) pp. 1-8.
[DOI][WoS][Pmid][serval:BIB_7DB9BDD1C012]
 
Stored red blood cells: a changing universe waiting for its map(s).
Lion N., Crettaz D., Rubin O., Tissot J.D., 2010. Journal of Proteomics, 73 (3) pp. 374-385.
[DOI][WoS][Pmid][serval:BIB_BD8058AAC434]
2009
 
About the Electrospray Ionization Source in Mass Spectrometry: Electrochemistry and On-chip Reactions
Prudent Michel, Méndez Manuel, Roussel Christophe, Su Bin, Lion Niels, Rossier Joël S., Girault Hubert H., 2009. CHIMIA International Journal for Chemistry, 63 (5) pp. 283-287. Peer-reviewed.
[DOI][WoS][serval:BIB_31DB5FA7B0A0]
 
Iontophoretic fraction collection for coupling capillary zone electrophoresis with matrix-assisted laser desorption/ionization mass spectrometry.
Busnel J.M., Josserand J., Lion N., Girault H.H., 2009. Analytical Chemistry, 81 (10) pp. 3867-3872. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F2795786B464]
2008
 
Application of proteomics to hematology: the revolution is starting.
Lion N., Tissot J.D., 2008. Expert Review of Proteomics, 5 (3) pp. 375-379.
[DOI][WoS][Pmid][serval:BIB_0723C9FDC9A6]
 
Electrokinetic supercharging for highly efficient peptide preconcentration in capillary zone electrophoresis.
Busnel J.M., Lion N., Girault H.H., 2008. Electrophoresis, 29 (7) pp. 1565-1572. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E4D060C2ACF2]
 
Electrospray micromixer chip for on-line derivatization and kinetic studies.
Abonnenc M., Dayon L., Perruche B., Lion N., Girault H.H., 2008. Analytical Chemistry, 80 (9) pp. 3372-3378. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_061E74CFEF88]
 
Microfabricated dual sprayer for on-line mass tagging of phosphopeptides.
Prudent M., Rossier J.S., Lion N., Girault H.H., 2008. Analytical Chemistry, 80 (7) pp. 2531-2538. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AB943046D66C]
 
Microparticles in stored red blood cells: an approach using flow cytometry and proteomic tools.
Rubin O., Crettaz D., Canellini G., Tissot J.D., Lion N., 2008. Vox Sanguinis, 95 (4) pp. 288-297.
[DOI][WoS][Pmid][serval:BIB_6E1DFE2C7433]
 
Oxidation of proteins: Basic principles and perspectives for blood proteomics.
Barelli S., Canellini G., Thadikkaran L., Crettaz D., Quadroni M., Rossier J.S., Tissot J.D., Lion N., 2008. Proteomics. Clinical Applications, 2 (2) pp. 142-157. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CB249B499874]
2007
 
Capillary electrophoresis as a second dimension to isoelectric focusing for peptide separation.
Busnel J.M., Lion N., Girault H.H., 2007. Analytical Chemistry, 79 (15) pp. 5949-5955. Peer-reviewed.
[DOI][Pmid][serval:BIB_0AF9924ECC22]
 
Design of an innovative analytical platform for allergen identification: Development of the separation unit
Busnel J.M., Lion N., Peltre G., Girault H.H., 2007. Allergy, 62 (83) p. 146. Peer-reviewed.
[WoS][serval:BIB_ABF5065DC96B]
 
Detection of proteins on membranes and in microchannels using copper staining combined with scanning electrochemical microscopy
Carano Maurizio, Lion Niels, Girault Hubert H., 2007. Journal of Electroanalytical Chemistry, 599 (2) pp. 349-355. Peer-reviewed.
[DOI][WoS][serval:BIB_6A08CEBBD885]
 
Modeling the isoelectric focusing of peptides in an OFFGEL multicompartment cell.
Lam H.T., Josserand J., Lion N., Girault H.H., 2007. Journal of Proteome Research, 6 (5) pp. 1666-1676. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D9C0C14DF03C]
2006
 
Multitrack electrospray chips.
Dayon L., Abonnenc M., Prudent M., Lion N., Girault H.H., 2006. Journal of Mass Spectrometry : Jms, 41 (11) pp. 1484-1490. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CE96C870E348]
2005
 
SPS' Digest: the Swiss Proteomics Society selection of proteomics articles
Hoogland C., Lion N., Palagi P. M., Sanchez J. C., Tissot J. D., 2005/08. Proteomics, 5 (12) pp. 3045-7.
[DOI][WoS][Pmid][serval:BIB_172A816433B8]
 
Chip electrospray mass spectrometry for carbohydrate analysis.
Zamfir A.D., Bindila L., Lion N., Allen M., Girault H.H., Peter-Katalinić J., 2005. Electrophoresis, 26 (19) pp. 3650-3673.
[DOI][WoS][Pmid][serval:BIB_E78F61A0238B]
 
Copper Staining/Labeling and Scanning Electrochemical Microscopy Readout of Proteins on Poly(vinylidene difluoride) Membranes
Carano Maurizio, Lion Niels, Girault Hubert H., 2005. CHIMIA International Journal for Chemistry, 59 (3) pp. 105-108. Peer-reviewed.
[DOI][WoS][serval:BIB_3943ED1FCF6C]
 
Microfluidics in system biology
Lion N., Rossier J.S., Girault H.H., 2005. Electrophoresis, 26 (19) pp. 3593-3593.
[DOI][WoS][serval:BIB_3D82D402F48C]
 
On-line counting of cysteine residues in peptides during electrospray ionization by electrogenerated tags and their application to protein identification.
Dayon L., Roussel C., Prudent M., Lion N., Girault H.H., 2005. Electrophoresis, 26 (1) pp. 238-247. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_89557D8158C3]
 
Salt removal during Off-Gel electrophoresis of protein samples.
Arnaud I.L., Josserand J., Jensen H., Lion N., Roussel C., Girault H.H., 2005. Electrophoresis, 26 (9) pp. 1650-1658. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5E06E9F71486]
 
Thin chip microsprayer system coupled to quadrupole time-of-flight mass spectrometer for glycoconjugate analysis.
Zamfir A.D., Lion N., Vukelic Z., Bindila L., Rossier J., Girault H.H., Peter-Katalinic J., 2005. Lab on a Chip, 5 (3) pp. 298-307. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0EB3D7616A6A]
2004
 
A thin chip microsprayer system coupled to Fourier transform ion cyclotron resonance mass spectrometry for glycopeptide screening.
Bindila L., Froesch M., Lion N., Vukelić Z., Rossier J.S., Girault H.H., Peter-Katalinić J., Zamfir A.D., 2004. Rapid Communications In Mass Spectrometry : Rcm, 18 (23) pp. 2913-2920. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C1B6E9005BC3]
 
Electrochemical and theoretical aspects of electrospray ionisation
Rohner Tatiana C., Lion Niels, Girault Hubert H., 2004. Physical Chemistry Chemical Physics, 6 (12) p. 3056. Peer-reviewed.
[DOI][WoS][serval:BIB_1A477BF5F638]
 
Flow-rate characterization of microfabricated polymer microspray emitters.
Lion N., Gellon J.O., Girault H.H., 2004. Rapid Communications In Mass Spectrometry : Rcm, 18 (14) pp. 1614-1620. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7C732819B4FB]
 
Generation of mass tags by the inherent electrochemistry of electrospray for protein mass spectrometry.
Roussel C., Dayon L., Lion N., Rohner T.C., Josserand J., Rossier J.S., Jensen H., Girault H.H., 2004. Journal of the American Society For Mass Spectrometry, 15 (12) pp. 1767-1779. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_68081043E7D7]
 
On-line electrochemical tagging of free cysteines during nanospray ionisation for mass spectrometry analysis
Roussel Christophe, Dayon Loic, Rohner Tatiana C., Lion Niels, Girault Hubert, Faupel Michel D., Meyrueis Patrick, 2004. Proceedings of The Society of Photo-Optical Instrumentation Engineers (SPIE), 5461 pp. 30-37. Peer-reviewed.
[DOI][WoS][serval:BIB_C3D96BC6DFA6]
 
Why the move to microfluidics for protein analysis?
Lion N., Reymond F., Girault H.H., Rossier J.S., 2004. Current Opinion in Biotechnology, 15 (1) pp. 31-37. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4FC628382D3F]
2003
 
Microfluidic systems in proteomics.
Lion N., Rohner T.C., Dayon L., Arnaud I.L., Damoc E., Youhnovski N., Wu Z.Y., Roussel C., Josserand J., Jensen H. et al., 2003. Electrophoresis, 24 (21) pp. 3533-3562. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_73C3E38CB56B]
 
On-chip protein sample desalting and preparation for direct coupling with electrospray ionization mass spectrometry.
Lion N., Gellon J.O., Jensen H., Girault H.H., 2003. Journal of Chromatography. A, 1003 (1-2) pp. 11-19. Peer-reviewed.
[WoS][Pmid][serval:BIB_7BEBCC4C9DAD]
 
Thin-chip microspray system for high-performance Fourier-transform ion-cyclotron resonance mass spectrometry of biopolymers.
Rossier J.S., Youhnovski N., Lion N., Damoc E., Becker S., Reymond F., Girault H.H., Przybylski M., 2003. Angewandte Chemie, 42 (1) pp. 54-58.
[WoS][Pmid][serval:BIB_BFC98A1CD545]
2002
 
Integration of a membrane-based desalting step in a microfabricated disposable polymer injector for mass spectrometric protein analysis.
Lion N., Gobry V., Jensen H., Rossier J.S., Girault H., 2002. Electrophoresis, 23 (20) pp. 3583-3588. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0A835DF8E3B9]
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