Alejandro Ocampo Méndez

Publications | Phd and Masters theses

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36 publications

2024 | 2023 | 2022 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2008 |
2024
ATAC-clock: An aging clock based on chromatin accessibility.
Morandini F., Rechsteiner C., Perez K., Praz V., Lopez Garcia G., Hinte L.C., von Meyenn F., Ocampo A., 2024/04. GeroScience, 46 (2) pp. 1789-1806. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8F11AE83CAF7]
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Agius Thomas, Emsley Raffaella, Lyon Arnaud, MacArthur Michael R., Kiesworo Kevin, Faivre Anna, Stavart Louis, Lambelet Martine, Legouis David, de Seigneux Sophie et al., 2024/02/05. Nature Communications, 15 (1).
[URN][DOI][Pmid][serval:BIB_4235435871D0]
 
DNA repair-deficient premature aging models display accelerated epigenetic age.
Perez K., Parras A., Picó S., Rechsteiner C., Haghani A., Brooke R., Mrabti C., Schoenfeldt L., Horvath S., Ocampo A., 2024/02. Aging cell, 23 (2) pp. e14058. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_71D5DC286FAE]
Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology.
Paine P.T., Nguyen A., Ocampo A., 2024/02. Aging cell, 23 (2) pp. e14039. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5DA79A2867C1]
2023
 
In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A., Vílchez-Acosta A., Desdín-Micó G., Picó S., Mrabti C., Montenegro-Borbolla E., Maroun C.Y., Haghani A., Brooke R., Del Carmen Maza M. et al., 2023/12. Nature aging, 3 (12) pp. 1509-1520. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CD54C85E7DB7]
 
Vitamin B12 emerges as key player during cellular reprogramming.
Vílchez-Acosta A., Desdín-Micó G., Ocampo A., 2023/11. Nature metabolism, 5 (11) pp. 1844-1845. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9107561C9F41]
 
Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.
Paine P.T., Rechsteiner C., Morandini F., Desdín-Micó G., Mrabti C., Parras A., Haghani A., Brooke R., Horvath S., Seluanov A. et al., 2023. Frontiers in aging, 4 p. 1323194. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5E8E2B81F5FB]
2022
 
Cellular reprogramming and the rise of rejuvenation biotech.
de Magalhães J.P., Ocampo A., 2022/06. Trends in biotechnology, 40 (6) pp. 639-642. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4C5B3C9CD219]
2020
 
Polyadenylation of mRNA as a novel regulatory mechanism of gene expression in temporal lobe epilepsy.
Parras A., de Diego-Garcia L., Alves M., Beamer E., Conte G., Jimenez-Mateos E.M., Morgan J., Ollà I., Hernandez-Santana Y., Delanty N. et al., 2020/07/01. Brain, 143 (7) pp. 2139-2153. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3E6948F651D6]
2019
 
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
Suzuki Keiichiro, Yamamoto Mako, Hernandez-Benitez Reyna, Li Zhe, Wei Christopher, Soligalla Rupa Devi, Aizawa Emi, Hatanaka Fumiyuki, Kurita Masakazu, Reddy Pradeep et al., 2019/08/23. Cell Research.
[DOI][Pmid][serval:BIB_C3359E43F3D6]
Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway
Hishida Tomoaki, Vazquez-Ferrer Eric, Hishida-Nozaki Yuriko, Sancho-Martinez Ignacio, Takahashi Yuta, Hatanaka Fumiyuki, Wu Jun, Ocampo Alejandro, Reddy Pradeep, Wu Min-Zu et al., 2019/07. Protein & Cell, 10 (7) pp. 485-495.
[URN][DOI][WoS][Pmid][serval:BIB_BF20E61B56A5]
2018
 
In vivo reprogramming of wound-resident cells generates skin epithelial tissue
Kurita Masakazu, Araoka Toshikazu, Hishida Tomoaki, O'Keefe David D., Takahashi Yuta, Sakamoto Akihisa, Sakurai Masahiro, Suzuki Keiichiro, Wu Jun, Yamamoto Mako et al., 2018/09. Nature, 561 (7722) pp. 243-247.
[DOI][WoS][Pmid][serval:BIB_B0DBFCC0249D]
2017
 
Regulation of Stem Cell Aging by Metabolism and Epigenetics.
Ren R., Ocampo A., Liu G.H., Izpisua Belmonte J.C., 2017/09/05. Cell metabolism, 26 (3) pp. 460-474. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F97C89F3FE2A]
 
Keeping the Rhythm while Changing the Lyrics: Circadian Biology in Aging.
Hatanaka F., Ocampo A., Izpisua Belmonte J.C., 2017/08/10. Cell, 170 (4) pp. 599-600. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8C4E7A6CA2EC]
 
Interspecies Chimerism with Mammalian Pluripotent Stem Cells.
Wu J., Platero-Luengo A., Sakurai M., Sugawara A., Gil M.A., Yamauchi T., Suzuki K., Bogliotti Y.S., Cuello C., Morales Valencia M. et al., 2017/01/26. Cell, 168 (3) pp. 473-486.e15. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A42FFFB27730]
2016
 
In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming.
Ocampo A., Reddy P., Martinez-Redondo P., Platero-Luengo A., Hatanaka F., Hishida T., Li M., Lam D., Kurita M., Beyret E. et al., 2016/12/15. Cell, 167 (7) pp. 1719-1733.e12. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_16E6DE45ED13]
 
Cellular Metabolism and Induced Pluripotency.
Wu J., Ocampo A., Belmonte JCI, 2016/09/08. Cell, 166 (6) pp. 1371-1385. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6F3A421D8F7F]
 
Anti-Aging Strategies Based on Cellular Reprogramming.
Ocampo A., Reddy P., Belmonte JCI, 2016/08. Trends in molecular medicine, 22 (8) pp. 725-738. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_19E74B6BB2F9]
 
Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging.
Ruetenik A.L., Ocampo A., Ruan K., Zhu Y., Li C., Zhai R.G., Barrientos A., 2016/07/26. Microbial cell, 3 (8) pp. 338-351. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A9996C52EE93]
 
Establishment of human iPSC-based models for the study and targeting of glioma initiating cells.
Sancho-Martinez I., Nivet E., Xia Y., Hishida T., Aguirre A., Ocampo A., Ma L., Morey R., Krause M.N., Zembrzycki A. et al., 2016/02/22. Nature communications, 7 p. 10743. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_22042A157C2B]
2015
 
Metabolic rescue in pluripotent cells from patients with mtDNA disease.
Ma H., Folmes C.D., Wu J., Morey R., Mora-Castilla S., Ocampo A., Ma L., Poulton J., Wang X., Ahmed R. et al., 2015/08/13. Nature, 524 (7564) pp. 234-238. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DC8C3794C341]
 
Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.
Zhang W., Li J., Suzuki K., Qu J., Wang P., Zhou J., Liu X., Ren R., Xu X., Ocampo A. et al., 2015/06/05. Science, 348 (6239) pp. 1160-1163. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7E1288D26ABF]
 
Selective elimination of mitochondrial mutations in the germline by genome editing.
Reddy P., Ocampo A., Suzuki K., Luo J., Bacman S.R., Williams S.L., Sugawara A., Okamura D., Tsunekawa Y., Wu J. et al., 2015/04/23. Cell, 161 (3) pp. 459-469. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C0F96924DAF9]
 
Stem cells. Holding your breath for longevity.
Ocampo A., Izpisua Belmonte J.C., 2015/03/20. Science, 347 (6228) pp. 1319-1320. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3DD9114CB800]
2014
 
In vivo activation of a conserved microRNA program induces mammalian heart regeneration.
Aguirre A., Montserrat N., Zacchigna S., Nivet E., Hishida T., Krause M.N., Kurian L., Ocampo A., Vazquez-Ferrer E., Rodriguez-Esteban C. et al., 2014/11/06. Cell stem cell, 15 (5) pp. 589-604. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_750954ED315B]
 
Regeneration: making muscle from hPSCs.
Zhu X., Fu L., Yi F., Liu G.H., Ocampo A., Qu J., Izpisua Belmonte J.C., 2014/10. Cell research, 24 (10) pp. 1159-1161. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_33705C981F98]
 
Reprogramming by lineage specifiers: blurring the lines between pluripotency and differentiation.
Sancho-Martinez I., Ocampo A., Izpisua Belmonte J.C., 2014/10. Current opinion in genetics & development, 28 pp. 57-63. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2B503C2B3AD5]
2013
 
Mitochondrial regulation in pluripotent stem cells.
Xu X., Duan S., Yi F., Ocampo A., Liu G.H., Izpisua Belmonte J.C., 2013/09/03. Cell metabolism, 18 (3) pp. 325-332. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_26314945F44A]
 
NAD+ salvage pathway proteins suppress proteotoxicity in yeast models of neurodegeneration by promoting the clearance of misfolded/oligomerized proteins.
Ocampo A., Liu J., Barrientos A., 2013/05/01. Human molecular genetics, 22 (9) pp. 1699-1708. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_173F750C281B]
2012
 
Mitochondrial respiratory thresholds regulate yeast chronological life span and its extension by caloric restriction.
Ocampo A., Liu J., Schroeder E.A., Shadel G.S., Barrientos A., 2012/07/03. Cell metabolism, 16 (1) pp. 55-67. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7B82D18BA987]
2011
 
Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling.
Pan Y., Schroeder E.A., Ocampo A., Barrientos A., Shadel G.S., 2011/06/08. Cell metabolism, 13 (6) pp. 668-678. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4AE667AD56FD]
 
Developing yeast models of human neurodegenerative disorders.
Ocampo A., Barrientos A., 2011. Methods in molecular biology, 793 pp. 113-127. Peer-reviewed.
[DOI][Pmid][serval:BIB_B10EC75E080F]
 
Quick and reliable assessment of chronological life span in yeast cell populations by flow cytometry.
Ocampo A., Barrientos A., 2011. Mechanisms of ageing and development, 132 (6-7) pp. 315-323. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_7F01270D8B86]
2010
 
Suppression of polyglutamine-induced cytotoxicity in Saccharomyces cerevisiae by enhancement of mitochondrial biogenesis.
Ocampo A., Zambrano A., Barrientos A., 2010/05. FASEB journal, 24 (5) pp. 1431-1441. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D27CC473FBAE]
2008
 
Repression of small toxic protein synthesis by the Sib and OhsC small RNAs.
Fozo E.M., Kawano M., Fontaine F., Kaya Y., Mendieta K.S., Jones K.L., Ocampo A., Rudd K.E., Storz G., 2008/12. Molecular microbiology, 70 (5) pp. 1076-1093. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_197541FA349D]
 
From the bakery to the brain business: developing inducible yeast models of human neurodegenerative disorders.
Ocampo A., Barrientos A., 2008/10. BioTechniques, 45 (4) pp. vii-xiv. Peer-reviewed.
[DOI][Pmid][serval:BIB_D49657C32C29]
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