Jeroen Geurts

Publications | Phd and Masters theses

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34 publications

In press | 2024 | 2023 | 2022 | 2021 | 2020 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2007 | 2006 |
In press
 
Evolution and advancements in genomics and epigenomics in OA research: How far we have come.
Ramos Y., Rice S.J., Ali S.A., Pastrello C., Jurisica I., Rai M.F., Collins K.H., Lang A., Maerz T., Geurts J. et al. Osteoarthritis and cartilage. Peer-reviewed.
[DOI][Pmid][serval:BIB_107D2E37E60B]
2024
Three decades of advancements in osteoarthritis research: insights from transcriptomic, proteomic, and metabolomic studies.
Rai M.F., Collins K.H., Lang A., Maerz T., Geurts J., Ruiz-Romero C., June R.K., Ramos Y., Rice S.J., Ali S.A. et al., 2024/04. Osteoarthritis and cartilage, 32 (4) pp. 385-397. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_D1B4F6D830DD]
 
Elevated secretion of pro-collagen I-alpha and vascular endothelial growth factor as biomarkers of acetabular labrum degeneration and calcification in hip osteoarthritis: An explant study.
Antoniadis A., Wegrzyn J., Omoumi P., Loisay L., Hügle T., Geurts J., 2024/01. Journal of orthopaedic translation, 44 pp. 19-25. Peer-reviewed.
[DOI][Pmid][serval:BIB_3DF8140D1E29]
2023
 
The Impact of Interventional Weight Loss on Bone Marrow Adipose Tissue in People Living with Obesity and Its Connection to Bone Metabolism.
Tencerova M., Duque G., Beekman K.M., Corsi A., Geurts J., Bisschop P.H., Paccou J., 2023/10/29. Nutrients, 15 (21). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BBB3D45B0862]
2022
Polg mtDNA mutator mice reveal limited involvement of vertebral bone loss in premature aging-related thoracolumbar hyperkyphosis.
Roessinger O., Hügle T., Walker U.A., Geurts J., 2022/12. Bone reports, 17 p. 101618. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2EF0F138D231]
Localization of Nerve Growth Factor Expression to Structurally Damaged Cartilaginous Tissues in Human Lumbar Facet Joint Osteoarthritis.
Seidel M.F., Netzer C., Chobaz V., Hügle T., Geurts J., 2022. Frontiers in immunology, 13 p. 783076. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9388EBD382CD]
2021
 
Distinct ex vivo biomarker profiles of calcified and non-calcified acetabular labrum tissues in primary hip OA
Antoniadis A., Wegrzyn J., Moradpour E., Hügle T., Geurts J., 2021/04. Osteoarthritis and Cartilage, 29 pp. S140.
[DOI][serval:BIB_039C7316FA35]
2020
Prematurely aging mitochondrial DNA mutator mice display subchondral osteopenia and chondrocyte hypertrophy without further osteoarthritis features.
Geurts J., Nasi S., Distel P., Müller-Gerbl M., Prolla T.A., Kujoth G.C., Walker U.A., Hügle T., 2020/01/28. Scientific reports, 10 (1) p. 1296. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_185C82687DF1]
2018
 
Novel Ex Vivo Human Osteochondral Explant Model of Knee and Spine Osteoarthritis Enables Assessment of Inflammatory and Drug Treatment Responses
Geurts Jeroen, Jurić Doria, Müller Miriam, Schären Stefan, Netzer Cordula, 2018/04/28. International Journal of Molecular Sciences, 19 (5) p. 1314.
[DOI][WoS][Pmid][serval:BIB_8CF2F29AF261]
 
Comparative Analysis of Bone Structural Parameters Reveals Subchondral Cortical Plate Resorption and Increased Trabecular Bone Remodeling in Human Facet Joint Osteoarthritis.
Netzer C., Distel P., Wolfram U., Deyhle H., Jost G.F., Schären S., Geurts J., 2018/03/14. International journal of molecular sciences, 19 (3). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67A5D0C1FE15]
Alterations of Subchondral Bone Progenitor Cells in Human Knee and Hip Osteoarthritis Lead to a Bone Sclerosis Phenotype.
Bianco D., Todorov A., Čengić T., Pagenstert G., Schären S., Netzer C., Hügle T., Geurts J., 2018/02/06. International journal of molecular sciences, 19 (2) p. 475 . Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_88D37611046A]
2017
 
Ascorbic Acid Attenuates Senescence of Human Osteoarthritic Osteoblasts.
Burger M.G., Steinitz A., Geurts J., Pippenger B.E., Schaefer D.J., Martin I., Barbero A., Pelttari K., 2017/11/24. International journal of molecular sciences, 18 (12). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_548A17EAD165]
 
What drives osteoarthritis?-synovial versus subchondral bone pathology.
Hügle T., Geurts J., 2017/09/01. Rheumatology, 56 (9) pp. 1461-1471. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_480DCB6987C3]
 
GEORG-SCHMORL-PRIZE OF THE GERMAN SPINE SOCIETY (DWG) 2016: Comparison of in vitro osteogenic potential of iliac crest and degenerative facet joint bone autografts for intervertebral fusion in lumbar spinal stenosis.
Geurts J., Ramp D., Schären S., Netzer C., 2017/05. European spine journal, 26 (5) pp. 1408-1415. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C59205880E40]
 
Marathon performance but not BMI affects post-marathon pro-inflammatory and cartilage biomarkers.
Mündermann A., Geurts J., Hügle T., Nickel T., Schmidt-Trucksäss A., Halle M., Hanssen H., 2017/04. Journal of sports sciences, 35 (7) pp. 711-718. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B744216B3F98]
2016
 
Characterization of subchondral bone histopathology of facet joint osteoarthritis in lumbar spinal stenosis.
Netzer C., Urech K., Hügle T., Benz R.M., Geurts J., Schären S., 2016/08. Journal of orthopaedic research, 34 (8) pp. 1475-1480. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1EB06E65E64B]
 
Elevated marrow inflammatory cells and osteoclasts in subchondral osteosclerosis in human knee osteoarthritis.
Geurts J., Patel A., Hirschmann M.T., Pagenstert G.I., Müller-Gerbl M., Valderrabano V., Hügle T., 2016/02. Journal of orthopaedic research, 34 (2) pp. 262-269. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3A89BE36D4EF]
2015
 
Increased Osseous (99m)Tc-DPD Uptake in End-Stage Ankle Osteoarthritis: Correlation Between SPECT-CT Imaging and Histologic Findings.
Paul J., Barg A., Kretzschmar M., Pagenstert G., Studler U., Hügle T., Wegner N.J., Valderrabano V., Geurts J., 2015/12. Foot & ankle international, 36 (12) pp. 1438-1447. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C75B0719C107]
 
Multicolor flow cytometry-based cellular phenotyping identifies osteoprogenitors and inflammatory cells in the osteoarthritic subchondral bone marrow compartment.
Pippenger B.E., Duhr R., Muraro M.G., Pagenstert G.I., Hügle T., Geurts J., 2015/11. Osteoarthritis and cartilage, 23 (11) pp. 1865-1869. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_19E47AE69F83]
 
An improved cartilage digestion method for research and clinical applications.
Centola M., Tonnarelli B., Hendriks J., van den Doel M., Feliciano S., Papadimitropoulos A., Piccinini E., Geurts J., Martin I., Barbero A., 2015/04. Tissue engineering. Part C, Methods, 21 (4) pp. 394-403. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DDE710FCF737]
 
FGF2 induces RANKL gene expression as well as IL1β regulated MHC class II in human bone marrow-derived mesenchymal progenitor stromal cells.
Bocelli-Tyndall C., Trella E., Frachet A., Zajac P., Pfaff D., Geurts J., Heiler S., Barbero A., Mumme M., Resink T.J. et al., 2015/01. Annals of the rheumatic diseases, 74 (1) pp. 260-266. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9E759CD4D7BC]
2014
 
Combination of immortalization and inducible death strategies to generate a human mesenchymal stromal cell line with controlled survival.
Bourgine P., Le Magnen C., Pigeot S., Geurts J., Scherberich A., Martin I., 2014/03. Stem cell research, 12 (2) pp. 584-598. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3F6C4348904C]
2013
 
Educational quality of YouTube videos on knee arthrocentesis.
Fischer J., Geurts J., Valderrabano V., Hügle T., 2013/10. Journal of clinical rheumatology, 19 (7) pp. 373-376. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_950C36147AA7]
2012
 
Aging and osteoarthritis: an inevitable encounter?
Hügle T., Geurts J., Nüesch C., Müller-Gerbl M., Valderrabano V., 2012. Journal of aging research, 2012 p. 950192. Peer-reviewed.
[DOI][Pmid][serval:BIB_9A467A369DA2]
2011
 
A novel Saa3-promoter reporter distinguishes inflammatory subtypes in experimental arthritis and human synovial fibroblasts.
Geurts J., Vermeij E.A., Pohlers D., Arntz O.J., Kinne R.W., van den Berg W.B., van de Loo F.A., 2011/07. Annals of the rheumatic diseases, 70 (7) pp. 1311-1319. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9E7788E87341]
 
Toll-like receptor 4 signalling is specifically TGF-beta-activated kinase 1 independent in synovial fibroblasts.
Geurts J., van den Brand B.T., Wolf A., Abdollahi-Roodsaz S., Arntz O.J., Kracht M., van den Berg W.B., van de Loo F.A., 2011/07. Rheumatology, 50 (7) pp. 1216-1225. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1B70D0588B56]
2010
 
S100A8 causes a shift toward expression of activatory Fcγ receptors on macrophages via toll-like receptor 4 and regulates Fcγ receptor expression in synovium during chronic experimental arthritis.
van Lent P.L., Grevers L.C., Schelbergen R., Blom A., Geurts J., Sloetjes A., Vogl T., Roth J., van den Berg W.B., 2010/11. Arthritis and rheumatism, 62 (11) pp. 3353-3364. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_67A228BFDB37]
 
A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis.
Arntz O.J., Geurts J., Veenbergen S., Bennink M.B., van den Brand B.T., Abdollahi-Roodsaz S., van den Berg W.B., van de Loo F.A., 2010. Arthritis research & therapy, 12 (2) pp. R61. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9376059D9D93]
 
Regulated promoters
Geurts Jeroen, van den Berg Wim B., van de Loo Fons A. J., 2010. pp. 147-159 dans Gene Therapy for Autoimmune and Inflammatory Diseases, Springer Basel.
[DOI][serval:BIB_9AA1F672B3B7]
2009
 
Computational design and application of endogenous promoters for transcriptionally targeted gene therapy for rheumatoid arthritis.
Geurts J., Joosten L.A., Takahashi N., Arntz O.J., Glück A., Bennink M.B., van den Berg W.B., van de Loo F.A., 2009/11. Molecular therapy, 17 (11) pp. 1877-1887. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5D33087F0EAF]
 
Involvement of the Wnt signaling pathway in experimental and human osteoarthritis: prominent role of Wnt-induced signaling protein 1.
Blom A.B., Brockbank S.M., van Lent P.L., van Beuningen H.M., Geurts J., Takahashi N., van der Kraan P.M., van de Loo F.A., Schreurs B.W., Clements K. et al., 2009/02. Arthritis and rheumatism, 60 (2) pp. 501-512. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_19D9E4116A70]
2007
 
Application of a disease-regulated promoter is a safer mode of local IL-4 gene therapy for arthritis.
Geurts J., Arntz O.J., Bennink M.B., Joosten L.A., van den Berg W.B., van de Loo F.A., 2007/12. Gene therapy, 14 (23) pp. 1632-1638. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_701957E28014]
2006
 
Gene therapy works in animal models of rheumatoid arthritis...so what!
van de Loo F.A., Geurts J., van den Berg W.B., 2006/10. Current rheumatology reports, 8 (5) pp. 386-393. Peer-reviewed.
[DOI][Pmid][serval:BIB_E8C501904F08]
 
Identification of small heat shock protein B8 (HSP22) as a novel TLR4 ligand and potential involvement in the pathogenesis of rheumatoid arthritis.
Roelofs M.F., Boelens W.C., Joosten L.A., Abdollahi-Roodsaz S., Geurts J., Wunderink L.U., Schreurs B.W., van den Berg W.B., Radstake T.R., 2006/06/01. Journal of immunology, 176 (11) pp. 7021-7027. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_46675D030AEC]
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