Philippe Abdel-Sayed

Publications | Phd and Masters theses

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50 publications

2023 | 2022 | 2021 | 2020 | 2019 | 2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2009 |
2023
Ex Vivo Functional Benchmarking of Hyaluronan-Based Osteoarthritis Viscosupplement Products: Comprehensive Assessment of Rheological, Lubricative, Adhesive, and Stability Attributes.
Porcello A., Hadjab F., Ajouaou M., Philippe V., Martin R., Abdel-Sayed P., Hirt-Burri N., Scaletta C., Raffoul W., Applegate L.A. et al., 2023/10/09. Gels, 9 (10) p. 808. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C10A7BF26F8E]
Autologous and Allogeneic Cytotherapies for Large Knee (Osteo)Chondral Defects: Manufacturing Process Benchmarking and Parallel Functional Qualification.
Philippe V., Jeannerat A., Peneveyre C., Jaccoud S., Scaletta C., Hirt-Burri N., Abdel-Sayed P., Raffoul W., Darwiche S., Applegate L.A. et al., 2023/09/16. Pharmaceutics, 15 (9) p. 2333. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C0D748D22C56]
 
Cutaneous Cell Therapy Manufacturing Timeframe Rationalization: Allogeneic Off-the-Freezer Fibroblasts for Dermo-Epidermal Combined Preparations (DE-FE002-SK2) in Burn Care.
Chen X., Laurent A., Liao Z., Jaccoud S., Abdel-Sayed P., Flahaut M., Scaletta C., Raffoul W., Applegate L.A., Hirt-Burri N., 2023/09/16. Pharmaceutics, 15 (9) p. 2334. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9797A6B9E5DD]
Bio-Enhanced Neoligaments Graft Bearing FE002 Primary Progenitor Tenocytes: Allogeneic Tissue Engineering & Surgical Proofs-of-Concept for Hand Ligament Regenerative Medicine.
Jeannerat A., Meuli J., Peneveyre C., Jaccoud S., Chemali M., Thomas A., Liao Z., Abdel-Sayed P., Scaletta C., Hirt-Burri N. et al., 2023/07/03. Pharmaceutics, 15 (7) p. 1873. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2E77B0FEB830]
 
Thermo-Responsive Hyaluronan-Based Hydrogels Combined with Allogeneic Cytotherapeutics for the Treatment of Osteoarthritis.
Porcello A., Gonzalez-Fernandez P., Jeannerat A., Peneveyre C., Abdel-Sayed P., Scaletta C., Raffoul W., Hirt-Burri N., Applegate L.A., Allémann E. et al., 2023/05/18. Pharmaceutics, 15 (5) p. 1528. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B21831AB42DC]
Primary Chondroprogenitors: Standardized & Versatile Allogeneic Cytotherapeutics
Laurent Alexis, Jeannerat Annick, Peneveyre Cédric, Scaletta Corinne, Philippe Virginie, Abdel-Sayed Philippe, Raffoul Wassim, Martin Robin, Hirt-Burri Nathalie, Applegate Lee Ann, 2023/05/17. Encyclopedia, 3 (2) pp. 622-641.
[URN][DOI][serval:BIB_E2F1EBB147A7]
 
Process Optimization and Efficacy Assessment of Standardized PRP for Tendinopathies in Sports Medicine: Retrospective Study of Clinical Files and GMP Manufacturing Records in a Swiss University Hospital.
Sebbagh P., Hirt-Burri N., Scaletta C., Abdel-Sayed P., Raffoul W., Gremeaux V., Laurent A., Applegate L.A., Gremion G., 2023/03/25. Bioengineering, 10 (4) p. 409. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E069875488C1]
Primary Progenitor Tenocytes: Cytotherapeutics and Cell-Free Derivatives
Laurent Alexis, Scaletta Corinne, Abdel-Sayed Philippe, Raffoul Wassim, Hirt-Burri Nathalie, Applegate Lee Ann, 2023/03/16. Encyclopedia, 3 (1) pp. 340-361.
[URN][DOI][serval:BIB_3A4195A8BE38]
 
Current Status of PRP Manufacturing Requirements & European Regulatory Frameworks: Practical Tools for the Appropriate Implementation of PRP Therapies in Musculoskeletal Regenerative Medicine.
Sebbagh P., Cannone A., Gremion G., Gremeaux V., Raffoul W., Hirt-Burri N., Michetti M., Abdel-Sayed P., Laurent A., Wardé N. et al., 2023/02/24. Bioengineering, 10 (3) p. 292. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_272C3A91FB7F]
Industrial Biotechnology Conservation Processes: Similarities with Natural Long-Term Preservation of Biological Organisms.
Laurent A., Scaletta C., Abdel-Sayed P., Raffoul W., Hirt-Burri N., Applegate L.A., 2023/01/31. Biotech, 12 (1) p. 15. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2479CFE45C72]
Lyophilized Progenitor Tenocyte Extracts: Sterilizable Cytotherapeutic Derivatives with Antioxidant Properties and Hyaluronan Hydrogel Functionalization Effects.
Laurent A., Porcello A., Jeannerat A., Peneveyre C., Coeur A., Abdel-Sayed P., Scaletta C., Michetti M., de Buys Roessingh A., Jordan O. et al., 2023/01/10. Antioxidants, 12 (1) p. 163. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B3E4B5B2BB84]
Retrospectives on Three Decades of Safe Clinical Experience with Allogeneic Dermal Progenitor Fibroblasts: High Versatility in Topical Cytotherapeutic Care.
Laurent A., Rey M., Scaletta C., Abdel-Sayed P., Michetti M., Flahaut M., Raffoul W., de Buys Roessingh A., Hirt-Burri N., Applegate L.A., 2023/01/04. Pharmaceutics, 15 (1) p. 184. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_543C281B1D65]
2022
 
Hyaluronan-Based Hydrogels as Functional Vectors for Standardised Therapeutics in Tissue Engineering and Regenerative Medicine
Porcello Alexandre, Laurent Alexis, Hirt-Burri Nathalie, Abdel-Sayed Philippe, de Buys Roessingh Anthony, Raffoul Wassim, Jordan Olivier, Allémann Eric, Applegate Lee Ann, 2022/03/29. pp. 119-148 dans Nanopharmaceuticals in Regenerative Medicine, CRC Press.
[DOI][serval:BIB_169632AE91A9]
Retrospective Analysis of Autologous Chondrocyte-Based Cytotherapy Production for Clinical Use: GMP Process-Based Manufacturing Optimization in a Swiss University Hospital.
Philippe V., Laurent A., Hirt-Burri N., Abdel-Sayed P., Scaletta C., Schneebeli V., Michetti M., Brunet J.F., Applegate L.A., Martin R., 2022/03/17. Cells, 11 (6) p. 1016. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FDC192E178F4]
Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa.
Patrulea V., Gan B.H., Perron K., Cai X., Abdel-Sayed P., Sublet E., Ducret V., Nerhot N.P., Applegate L.A., Borchard G. et al., 2022/03/15. Carbohydrate polymers, 280 p. 119025. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_40DB7D6879C5]
Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling.
Nasrollahzadeh N., Karami P., Wang J., Bagheri L., Guo Y., Abdel-Sayed P., Laurent-Applegate L., Pioletti D.P., 2022/03/08. eLife, 11 pp. e72068. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_415F6782807D]
 
Biotechnology and Cytotherapeutics: The Swiss Progenitor-Cell Transplantation Program
Laurent Alexis, Scaletta Corinne, Abdel-Sayed Philippe, Michetti Murielle, de Buys Roessingh Anthony, Raffoul Wassim, Hirt-Burri Nathalie, Applegate Lee Ann, 2022/01/30. Encyclopedia, 2 (1) pp. 336-364.
[DOI][serval:BIB_C48CB1FFEEE7]
2021
Combination of Hyaluronan and Lyophilized Progenitor Cell Derivatives: Stabilization of Functional Hydrogel Products for Therapeutic Management of Tendinous Tissue Disorders.
Laurent A., Porcello A., Fernandez P.G., Jeannerat A., Peneveyre C., Abdel-Sayed P., Scaletta C., Hirt-Burri N., Michetti M., de Buys Roessingh A. et al., 2021/12/19. Pharmaceutics, 13 (12) p. 2196. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DBCEF906F288]
Back to the Cradle of Cytotherapy: Integrating a Century of Clinical Research and Biotechnology-Based Manufacturing for Modern Tissue-Specific Cellular Treatments in Switzerland.
Laurent A., Abdel-Sayed P., Scaletta C., Laurent P., Laurent E., Michetti M., de Buys Roessingh A., Raffoul W., Hirt-Burri N., Applegate L.A., 2021/12/17. Bioengineering, 8 (12) p. 221. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3E261CA71905]
Human Platelet Lysate as an Alternative to Autologous Serum for Human Chondrocyte Clinical Use.
Philippe V., Laurent A., Abdel-Sayed P., Hirt-Burri N., Ann Applegate L., Martin R., 2021/12. Cartilage, 13 (1_suppl) pp. 509S-518S. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_72C79A8BAF5C]
Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.
Chemali M., Laurent A., Scaletta C., Waselle L., Simon J.P., Michetti M., Brunet J.F., Flahaut M., Hirt-Burri N., Raffoul W. et al., 2021/09/30. Journal of burn care & research, 42 (5) pp. 911-924. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2FE665354651]
Corrigendum to: Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs.
Chemali M., Laurent A., Scaletta C., Waselle L., Simon J.P., Michetti M., Brunet J.F., Flahaut M., Hirt-Burri N., Raffoul W. et al., 2021/09/30..
[URN][DOI][WoS][Pmid][serval:BIB_5E6F00556428]
 
Effective Management Of Topical Nosocomial Aspergillus Spp. Infections In Three Severely Burned Patients.
Pantet O., Laurent A., Abdel-Sayed P., Hirt-Burri N., Michetti M., Raffoul W., Monod M., Applegate L.A., de Buys Roessingh A.S., 2021/09/30. Annals of burns and fire disasters, 34 (3) pp. 235-239. Peer-reviewed.
[Pmid][serval:BIB_BC2643BBAC74]
 
Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative Medicine.
Laurent A., Abdel-Sayed P., Hirt-Burri N., Scaletta C., Michetti M., de Buys Roessingh A., Raffoul W., Applegate L.A., 2021/09/24. Cells, 10 (10) p. 2526. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3A4B102DBA12]
Optimized Manufacture of Lyophilized Dermal Fibroblasts for Next-Generation Off-the-Shelf Progenitor Biological Bandages in Topical Post-Burn Regenerative Medicine.
Laurent A., Scaletta C., Abdel-Sayed P., Michetti M., Flahaut M., Simon J.P., Roessingh A.B., Raffoul W., Hirt-Burri N., Applegate L.A., 2021/08/23. Biomedicines, 9 (8) p. 1072. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4C8CFF2F5FAC]
 
Bonnes Pratiques de Fabrication et thérapies cellulaires au chevet des grands brûlés romands
Laurent Alexis, Abdel-Sayed Philippe, Chemale Michèle, Hirt-Burri Nathalie, Raffoul Wassim, Applegate Lee Ann, de Buys Roesingh Anthony S, 2021/07/01. PharmaJournal Suisse, 2021 (6/7) pp. 10-14.
[serval:BIB_06210850C49D]
Design optimization of bidirectional arterial perfusion cannula.
Abdel-Sayed S., Ferrari E., Abdel-Sayed P., Wilhelm M., von Segesser L.K., Berdajs D., 2021/04/26. Journal of cardiothoracic surgery, 16 (1) p. 114. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6C6290984774]
Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation.
Laurent A., Abdel-Sayed P., Grognuz A., Scaletta C., Hirt-Burri N., Michetti M., de Buys Roessingh A.S., Raffoul W., Kronen P., Nuss K. et al., 2021/04/03. Biomedicines, 9 (4) p. 380. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E2509CEBF7D3]
Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care
Al-Dourobi Karim, Laurent Alexis, Deghayli Lina, Flahaut Marjorie, Abdel-Sayed Philippe, Scaletta Corinne, Michetti Murielle, Waselle Laurent, Simon Jeanne-Pascale, El Ezzi Oumama et al., 2021/02/28. Pharmaceuticals, 14 (3) p. 201.
[URN][DOI][WoS][Pmid][serval:BIB_5D7C504E9636]
 
Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care.
Al-Dourobi K., Laurent A., Deghayli L., Flahaut M., Abdel-Sayed P., Scaletta C., Michetti M., Waselle L., Simon J.P., Ezzi O.E. et al., 2021/02/28. Pharmaceuticals, 14 (3) p. 201. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FFCCB34FEBF6]
Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation.
Laurent A., Abdel-Sayed P., Ducrot A., Hirt-Burri N., Scaletta C., Jaccoud S., Nuss K., Roessingh ASB, Raffoul W., Pioletti D. et al., 2021/02/09. Biomolecules, 11 (2) p. 250. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E4DA1AC43247]
2020
Implications of chlorhexidine use in burn units for wound healing.
Abdel-Sayed P., Tornay D., Hirt-Burri N., de Buys Roessingh A., Raffoul W., Applegate L.A., 2020/08. Burns, 46 (5) pp. 1150-1156. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BF527DF952BE]
 
Effect of blood viscosity on the performance of virtually wall-less venous cannulas.
Abdel-Sayed S., Abdel-Sayed P., Berdaj D., Ferrari E., Halbe M., von Segesser L.K., Maisano F., 2020/07. Perfusion, 35 (5) pp. 393-396. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5B36E708864A]
 
New bidirectional arterial perfusion device.
Abdel-Sayed S., Ferrari E., Abdel-Sayed P., Wilhelm M., Halbe M., von Segesser L.K., Maisano F., Berdajs D., 2020/07. The International journal of artificial organs, 43 (7) pp. 433-436. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0FFB5AD4FA64]
 
Reply to the Letter to the Editor on "The use of antiseptics in burn wounds - our perspective".
Abdel-Sayed P., Tornay D., Hirt-Burri N., de Buys Roessingh A., Raffoul W., Applegate L.A., 2020/06. Burns, 46 (4) pp. 981-982. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D10407241EE1]
Surgical Management Evolution Between 2 Massive Burn Cases at 17-Year Interval: Contribution of Cell Therapies in Improving the Surgical Care.
Monnier S., Abdel-Sayed P., Roessingh A.B., Hirt-Burri N., Chemali M., Applegate L.A., Raffoul W., 2020. Cell transplantation, 29 p. 963689720973642. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F1F193A6A252]
2019
Evolution of Biological Bandages as First Cover for Burn Patients.
Abdel-Sayed P., Hirt-Burri N., de Buys Roessingh A., Raffoul W., Applegate L.A., 2019/11/01. Advances in wound care, 8 (11) pp. 555-564. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BC7604AFE085]
Cell therapies for skin regeneration: an overview of 40 years of experience in burn units.
Abdel-Sayed P., Michetti M., Scaletta C., Flahaut M., Hirt-Burri N., de Buys Roessingh A., Raffoul W., Applegate L.A., 2019/05/06. Swiss medical weekly, 149 pp. w20079. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_63158D24E889]
2017
 
Fabrication of an Open Microfluidic Device for Immunoblotting.
Abdel-Sayed P., Yamauchi K.A., Gerver R.E., Herr A.E., 2017/09/19. Analytical chemistry, 89 (18) pp. 9643-9648. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_20E9ADD8651A]
2016
Corrigendum: Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages.
Abdel-Sayed P., Kaeppeli A., Siriwardena T., Darbre T., Perron K., Jafari P., Reymond J.L., Pioletti D.P., Applegate L.A., 2016/04/07. Scientific reports, 6 p. 23872. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5E087450EE86]
Anti-Microbial Dendrimers against Multidrug-Resistant P. aeruginosa Enhance the Angiogenic Effect of Biological Burn-wound Bandages.
Abdel-Sayed P., Kaeppeli A., Siriwardena T., Darbre T., Perron K., Jafari P., Reymond J.L., Pioletti D.P., Applegate L.A., 2016/02/25. Scientific reports, 6 p. 22020. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5EEB7A8C68D9]
2015
 
Impact of synovial fluid flow on temperature regulation in knee cartilage.
Moghadam M.N., Abdel-Sayed P., Camine V.M., Pioletti D.P., 2015/01/21. Journal of biomechanics, 48 (2) pp. 370-374. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2ABA2894F4BF]
 
Strategies for improving the repair of focal cartilage defects.
Abdel-Sayed P., Pioletti D.P., 2015. Nanomedicine, 10 (18) pp. 2893-2905. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_15E500047850]
2014
 
Intrinsic viscoelasticity increases temperature in knee cartilage under physiological loading.
Abdel-Sayed P., Moghadam M.N., Salomir R., Tchernin D., Pioletti D.P., 2014/02. Journal of the mechanical behavior of biomedical materials, 30 pp. 123-130. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_24747FA8AD1A]
 
The role of energy dissipation of polymeric scaffolds in the mechanobiological modulation of chondrogenic expression.
Abdel-Sayed P., Darwiche S.E., Kettenberger U., Pioletti D.P., 2014/02. Biomaterials, 35 (6) pp. 1890-1897. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_71B6B06E0FA7]
2013
 
Comparison of radial deformability of stent posts of different aortic bioprostheses.
Kalejs M., Lacis R., Kasyanov V., Ozolanta I., Abdel Sayed P., Stradins P., von Segesser L.K., 2013/02. Interactive cardiovascular and thoracic surgery, 16 (2) pp. 129-133. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8F7B7D372CF9]
 
Cartilage self-heating contributes to chondrogenic expression
Abdel-Sayed Philippe, 2013. European Cells and Materials.
[DOI][serval:BIB_5433572B6C6E]
 
Dissipation can act as a mechanobiological signal in cartilage differentiation
Abdel-Sayed Philippe, 2013. dans ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE).
[DOI][serval:BIB_105BAB3858C5]
2011
 
Rapid Prototyping for Training Purposes in Cardiovascular Surgery
Abdel-Sayed Philippe, von Segesser Ludwig Karl, 2011/09/22. dans Advanced Applications of Rapid Prototyping Technology in Modern Engineering, InTech.
[DOI][serval:BIB_7FE41F3D521A]
2009
 
A new training set-up for trans-apical aortic valve replacement.
Abdel-Sayed P., Kalejs M., von Segesser L.K., 2009/06. Interactive cardiovascular and thoracic surgery, 8 (6) pp. 599-601. Peer-reviewed.
[DOI][Pmid][serval:BIB_44CD8EF10EE5]
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