Dmitri Firsov

Publications | Mémoires et thèses

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70 publications

2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2005 | 2004 | 2003 | 2002 | 2001 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 |
Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock.
Bignon Y., Wigger L., Ansermet C., Weger B.D., Lagarrigue S., Centeno G., Durussel F., Götz L., Ibberson M., Pradervand S. et al., 2023/04/17. The Journal of clinical investigation, 133 (8) pp. e167133. Peer-reviewed.
 
Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes.
Ansermet C., Centeno G., Bignon Y., Ortiz D., Pradervand S., Garcia A., Menin L., Gachon F., Yoshihara H.A., Firsov D., 2022/03. Kidney international, 101 (3) pp. 563-573. Peer-reviewed.
 
Renal tubular peroxisomes are dispensable for normal kidney function.
Ansermet C., Centeno G., Pradervand S., Harmacek D., Garcia A., Daraspe J., Kocherlakota S., Baes M., Bignon Y., Firsov D., 2022/02/22. JCI insight, 7 (4) pp. e155836. Peer-reviewed.
 
Xenotropic and polytropic retrovirus receptor 1 regulates procoagulant platelet polyphosphate.
Mailer R.K., Allende M., Heestermans M., Schweizer M., Deppermann C., Frye M., Pula G., Odeberg J., Gelderblom M., Rose-John S. et al., 2021/03/11. Blood, 137 (10) pp. 1392-1405. Peer-reviewed.
Renal tubular arginase-2 participates in the formation of the corticomedullary urea gradient and attenuates kidney damage in ischemia-reperfusion injury in mice.
Ansermet C., Centeno G., Lagarrigue S., Nikolaeva S., Yoshihara H.A., Pradervand S., Barras J.L., Dattner N., Rotman S., Amati F. et al., 2020/07. Acta physiologica, 229 (3) pp. e13457. Peer-reviewed.
The intrinsic circadian clock in podocytes controls glomerular filtration rate.
Ansermet C., Centeno G., Nikolaeva S., Maillard M.P., Pradervand S., Firsov D., 2019/11/06. Scientific reports, 9 (1) p. 16089. Peer-reviewed.
Circadian rhythms and the kidney.
Firsov D., Bonny O., 2018/10. Nature reviews. Nephrology, 14 (10) pp. 626-635. Peer-reviewed.
 
Redox-Dependent Bone Alkaline Phosphatase Dysfunction Drives Part of the Complex Bone Phenotype in Mice Deficient for <i>Memo1</i>.
Moor M.B., Ramakrishnan S.K., Legrand F., Dolder S., Siegrist M., Durussel F., Centeno G., Firsov D., Hynes N.E., Hofstetter W. et al., 2018/07. JBMR plus, 2 (4) pp. 195-205. Peer-reviewed.
 
Deletion of Xenotropic and Polytropic Retrovirus Receptor 1 in mouse nephron causes renal Fanconi syndrome and hypophosphatemic rickets [857.9]
Ansermet C., Moor M., Centeno G., Auberson M., Hu D., Barron R., Nikolaeva S., Haenzi B., Katanaeva N., Gautschi I. et al., 2017/04/30., Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting pp. n.p. dans Faseb Journal.
Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron.
Ansermet C., Moor M.B., Centeno G., Auberson M., Hu D.Z., Baron R., Nikolaeva S., Haenzi B., Katanaeva N., Gautschi I. et al., 2017/04. Journal of the American Society of Nephrology : JASN, 28 (4) pp. 1073-1078. Peer-reviewed.
Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition.
Nikolaeva S., Ansermet C., Centeno G., Pradervand S., Bize V., Mordasini D., Henry H., Koesters R., Maillard M., Bonny O. et al., 2016/10. Journal of the American Society of Nephrology : JASN, 27 (10) pp. 2997-3004. Peer-reviewed.
Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.
Piazzon N., Bernet F., Guihard L., Leonhard W.N., Urfer S., Firsov D., Chehade H., Vogt B., Piergiovanni S., Peters D.J. et al., 2015/03. Journal of Translational Medicine, 13 p. 103. Peer-reviewed.
 
No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse.
Preitner F., Pimentel A., Metref S., Berthonneche C., Sarre A., Moret C., Rotman S., Centeno G., Firsov D., Thorens B., 2015. Kidney International, 87 (5) pp. 940-947.
Circadian glomerular function: from physiology to molecular and therapeutical aspects.
Wuerzner G., Firsov D., Bonny O., 2014/08. Nephrology, Dialysis, Transplantation, 29 (8) pp. 1475-1480. Peer-reviewed.
BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis.
Béguin P., Nagashima K., Mahalakshmi R.N., Vigot R., Matsunaga A., Miki T., Ng M.Y., Ng Y.J., Lim C.H., Tay H.S. et al., 2014. Journal of Cell Biology, 205 (2) pp. 233-249. Peer-reviewed.
Local Renal Circadian Clocks Control Fluid-Electrolyte Homeostasis and BP.
Tokonami N., Mordasini D., Pradervand S., Centeno G., Jouffe C., Maillard M., Bonny O., Gachon F., Gomez R.A., Sequeira-Lopez M.L. et al., 2014. Journal of the American Society of Nephrology, 25 (7) pp. 1430-1439.
Circadian regulation of renal function and potential role in hypertension.
Bonny O., Firsov D., 2013. Current Opinion In Nephrology and Hypertension, 22 (4) pp. 439-444.
Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
O'Seaghdha C.M., Wu H., Yang Q., Kapur K., Guessous I., Zuber A.M., Köttgen A., Stoudmann C., Teumer A., Kutalik Z. et al., 2013. Plos Genetics, 9 (9) pp. e1003796.
α-Ketoglutarate regulates acid-base balance through an intrarenal paracrine mechanism.
Tokonami N., Morla L., Centeno G., Mordasini D., Ramakrishnan S.K., Nikolaeva S., Wagner C.A., Bonny O., Houillier P., Doucet A. et al., 2013. Journal of Clinical Investigation, 123 (7) pp. 3166-3171. Peer-reviewed.
 
Circadian expression of H,K-ATPase type 2 contributes to the stability of plasma K⁺ levels.
Salhi A., Centeno G., Firsov D., Crambert G., 2012. FASEB Journal, 26 (7) pp. 2859-2867.
Role of the renal circadian timing system in maintaining water and electrolytes homeostasis.
Firsov D., Tokonami N., Bonny O., 2012. Molecular and Cellular Endocrinology, 349 (1) pp. 51-55.
The circadian clock modulates renal sodium handling.
Nikolaeva S., Pradervand S., Centeno G., Zavadova V., Tokonami N., Maillard M., Bonny O., Firsov D., 2012. Journal of the American Society of Nephrology, 23 (6) pp. 1019-1026. Peer-reviewed.
The role of circadian timing system on drug metabolism and detoxification.
Gachon F., Firsov D., 2011. Expert Opinion on Drug Metabolism and Toxicology, 7 (2) pp. 147-158. Peer-reviewed.
A comprehensive analysis of gene expression profiles in distal parts of the mouse renal tubule.
Pradervand S., Zuber Mercier A., Centeno G., Bonny O., Firsov D., 2010. Pflügers Archiv, 460 (6) pp. 925-952.
Circadian regulation of renal function.
Firsov D., Bonny O., 2010. Kidney International, 78 (7) pp. 640-645.
 
Circadian clock and the concept of homeostasis.
Bonny O., Firsov D., 2009. Cell Cycle, 8 (24) pp. 4015-4016.
 
Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy.
Preitner F., Bonny O., Laverrière A., Rotman S., Firsov D., Da Costa A., Metref S., Thorens B., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (36) pp. 15501-15506.
 
Molecular clock is involved in predictive circadian adjustment of renal function.
Zuber A.M., Centeno G., Pradervand S., Nikolaeva S., Maquelin L., Cardinaux L., Bonny O., Firsov D., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (38) pp. 16523-16528. Peer-reviewed.
 
Mouse GLUT9: evidences for a urate uniporter.
Bibert S., Hess S.K., Firsov D., Thorens B., Geering K., Horisberger J.D., Bonny O., 2009. American Journal of Physiology. Renal Physiology, 297 (3) pp. F612-F619. Peer-reviewed.
Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes.
Rougier J.S., Muller O., Berger S., Centeno G., Schütz G., Firsov D., Abriel H., 2008. Pflügers Archiv, 456 (2) pp. 407-412. Peer-reviewed.
 
Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus oocytes: role of furin-mediated endogenous proteolysis.
Harris M., Garcia-Caballero A., Stutts M.J., Firsov D., Rossier B.C., 2008. Journal of Biological Chemistry, 283 (12) pp. 7455-7463. Peer-reviewed.
 
Vasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3
Boulkroun S., Ruffieux-Daidie D., Vitagliano J. J., Poirot O., Charles R. P., Lagnaz D., Firsov D., Kellenberger S., Staub O., 2008. American Journal of Physiology - Renal Physiology, 295 (4) pp. F889-F900. Peer-reviewed.
 
A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.
Harris M., Firsov D., Vuagniaux G., Stutts M.J., Rossier B.C., 2007. Journal of Biological Chemistry, 282 (1) pp. 58-64. Peer-reviewed.
 
Identification of corticosteroid-regulated genes in cardiomyocytes by serial analysis of gene expression.
Muller O., Pradervand S., Berger S., Centeno G., Milet A., Nicod P., Pedrazzini T., Tronche F., Schütz G., Chien K. et al., 2007. Genomics, 89 (3) pp. 370-377.
 
Increased renal responsiveness to vasopressin and enhanced V2 receptor signaling in RGS2-/- mice.
Zuber A.M., Singer D., Penninger J.M., Rossier B.C., Firsov D., 2007. Journal of the American Society of Nephrology, 18 (6) pp. 1672-1678.
 
Les antagonistes du récepteur minératocorticoïde
Muller O., Firsov D., Seydoux C., 2007. Revue Médicale Suisse, 3 (113) pp. 1401-1404.
 
Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism.
Michlig S., Harris M., Loffing J., Rossier B.C., Firsov D., 2005. Journal of Biological Chemistry, 280 (46) pp. 38264-38270. Peer-reviewed.
 
ERK1/2 controls Na,K-ATPase activity and transepithelial sodium transport in the principal cell of the cortical collecting duct of the mouse kidney.
Michlig S., Mercier A., Doucet A., Schild L., Horisberger J.D., Rossier B.C., Firsov D., 2004. Journal of Biological Chemistry, 279 (49) pp. 51002-51012. Peer-reviewed.
 
Revisiting sodium and water reabsorption with functional genomics tools.
Firsov D., 2004/01. Current opinion in nephrology and hypertension, 13 (1) pp. 59-65. Peer-reviewed.
 
Small proline-rich protein 1A is a gp130 pathway- and stress-inducible cardioprotective protein.
Pradervand S., Yasukawa H., Muller O.G., Kjekshus H., Nakamura T., St Amand T.R., Yajima T., Matsumura K., Duplain H., Iwatate M. et al., 2004. EMBO Journal, 23 (22) pp. 4517-4525.
 
Aldosterone action in the heart.
Firsov D., Muller O.G., 2003/06. Pflügers Archiv, 446 (3) pp. 328-333.
 
Mineralocorticoid effects in the kidney: correlation between alphaENaC, GILZ, and Sgk-1 mRNA expression and urinary excretion of Na+ and K+.
Muller O.G., Parnova R.G., Centeno G., Rossier B.C., Firsov D., Horisberger J.D., 2003. Journal of the American Society of Nephrology, 14 (5) pp. 1107-1115.
 
N-Glycosylation and conserved cysteine residues in RAMP3 play a critical role for the functional expression of CRLR/RAMP3 adrenomedullin receptor.
Flahaut M., Pfister C., Rossier B.C., Firsov D., 2003. Biochemistry, 42 (34) pp. 10333-10341.
 
A novel vasopressin-induced transcript promotes MAP kinase activation and ENaC downregulation.
Nicod M., Michlig S., Flahaut M., Salinas M., Fowler Jaeger N., Horisberger J.D., Rossier B.C., Firsov D., 2002. EMBO Journal, 21 (19) pp. 5109-5117.
 
Respective roles of calcitonin receptor-like receptor (CRLR) and receptor activity-modifying proteins (RAMP) in cell surface expression of CRLR/RAMP heterodimeric receptors.
Flahaut M., Rossier B.C., Firsov D., 2002. Journal of Biological Chemistry, 277 (17) pp. 14731-14737. Peer-reviewed.
 
Transcriptome of a mouse kidney cortical collecting duct cell line: effects of aldosterone and vasopressin.
Robert-Nicoud M., Flahaut M., Elalouf J.M., Nicod M., Salinas M., Bens M., Doucet A., Wincker P., Artiguenave F., Horisberger J.D. et al., 2001. Proceedings of the National Academy of Sciences of the United States of America, 98 (5) pp. 2712-2716.
 
Involvement of G protein-coupled receptor kinases and arrestins in desensitization to follicle-stimulating hormone action.
Troispoux C., Guillou F., Elalouf J.M., Firsov D., Iacovelli L., De Blasi A., Combarnous Y., Reiter E., 1999. Molecular Endocrinology, 13 (9) pp. 1599-1614.
 
Mutational analysis of cysteine-rich domains of the epithelium sodium channel (ENaC). Identification of cysteines essential for channel expression at the cell surface.
Firsov D., Robert-Nicoud M., Gruender S., Schild L., Rossier B.C., 1999. Journal of Biological Chemistry, 274 (5) pp. 2743-2749.
Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes.
Chraïbi A., Vallet V., Firsov D., Hess S.K., Horisberger J.D., 1998. Journal of General Physiology, 111 (1) pp. 127-138.
 
Rat G protein-coupled receptor kinase GRK4: identification, functional expression, and differential tissue distribution of two splice variants.
Virlon B., Firsov D., Cheval L., Reiter E., Troispoux C., Guillou F., Elalouf J.M., 1998. Endocrinology, 139 (6) pp. 2784-2795.
 
The heterotetrameric architecture of the epithelial sodium channel (ENaC).
Firsov D., Gautschi I., Merillat A.M., Rossier B.C., Schild L., 1998. EMBO Journal, 17 (2) pp. 344-352.
 
A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel.
Gründer S., Firsov D., Chang S.S., Jaeger N.F., Gautschi I., Schild L., Lifton R.P., Rossier B.C., 1997. EMBO Journal, 16 (5) pp. 899-907.
Identification of amino acid residues in the alpha, beta, and gamma subunits of the epithelial sodium channel (ENaC) involved in amiloride block and ion permeation.
Schild L., Schneeberger E., Gautschi I., Firsov D., 1997. Journal of General Physiology, 109 (1) pp. 15-26.
 
Molecular cloning of two rat GRK6 splice variants.
Firsov D., Elalouf J.M., 1997. American Journal of Physiology. Cell Physiology, 273 (3 Pt 1) pp. C953-C961.
 
The gamma subunit is a specific component of the Na,K-ATPase and modulates its transport function.
Béguin P., Wang X., Firsov D., Puoti A., Claeys D., Horisberger J.D., Geering K., 1997. EMBO Journal, 16 (14) pp. 4250-4260.
 
Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach.
Firsov D., Schild L., Gautschi I., Mérillat A.M., Schneeberger E., Rossier B.C., 1996. Proceedings of the National Academy of Sciences of the United States of America, 93 (26) pp. 15370-15375.
 
Localization of mRNAs encoding Ca2+-inhibitable adenylyl cyclases along the renal tubule. Functional consequences for regulation of the cAMP content.
Chabardès D., Firsov D., Aarab L., Clabecq A., Bellanger A.C., Siaume-Perez S., Elalouf J.M., 1996. Journal of Biological Chemistry, 271 (32) pp. 19264-19271.
 
Arachidonic acid inhibits hormone-stimulated cAMP accumulation in the medullary thick ascending limb of the rat kidney by a mechanism sensitive to pertussis toxin.
Firsov D., Aarab L., Mandon B., Siaume-Perez S., de Rouffignac C., Chabardès D., 1995. Pflügers Archiv, 429 (5) pp. 636-646.
 
Quantitative RT-PCR analysis of calcitonin receptor mRNAs in the rat nephron.
Firsov D., Bellanger A.C., Marsy S., Elalouf J.M., 1995. American Journal of Physiology. Renal Fluid and Electrolyte Physiology, 269 (5 Pt 2) pp. F702-F709.
 
Molecular analysis of vasopressin receptors in the rat nephron. Evidence for alternative splicing of the V2 receptor.
Firsov D., Mandon B., Morel A., Merot J., Le Maout S., Bellanger A.C., de Rouffignac C., Elalouf J.M., Buhler J.M., 1994. Pflügers Archiv, 429 (1) pp. 79-89.
 
The effect of arachidonic acid on the hydroosmotic action of vasopressin in frog urinary bladder.
Firsov D.L., Parnova R.G., 1994. Biochimica et Biophysica Acta. Molecular Cell Research, 1220 (3) pp. 305-309. Peer-reviewed.
 
Insulin stimulates Na+, Cl-, Ca2+, and Mg2+ transports in TAL of mouse nephron: cross-potentiation with AVP.
Mandon B., Siga E., Chabardes D., Firsov D., Roinel N., De Rouffignac C., 1993. American Journal of Physiology, 265 (3 Pt 2) pp. F361-F369.
 
Does the gradual hydroosmotic response to antidiuretic hormone depend on intracellular cAMP accumulation or on the formation of intramembrane particle aggregates?
Natochin YuV E.I., Shakhmatova E.I., Firsov D.L., Parnova R.G., Reznik L.V., Natochin MYu V., Romanov V., 1992. Pflügers Archiv, 422 (1) pp. 3-8.
 
Svobodnaia arakhidonovaia kislota kak messendzher i moduliator v mekhanizme gidroosmoticheskogo éffekta vazopressina [Free arachidonic acid as a messenger and modulator in the mechanism of the hydroosmotic effect of vasopressin].
Firsov D.L., Parnova R.G., Natochin I.u.V., 1992. Doklady Akademii Nauk, 325 (6) pp. 1252-1254.
 
ADH-dependent phosphoinositide signalling system and prostaglandin E production in the frog urinary bladder.
Parnova R.G., Firsov D.L., 1991. Cellular Signalling, 3 (2) pp. 135-143.
 
Mechanism of postflight decline in osmotic concentration of urine in cosmonauts.
Natochin YuV A.I., Grigoriev A.I., Noskov V.B., Parnova R.G., Sukhanov YuV D.L., Firsov D.L., Shakhmatova E.I., 1991. Aviation, Space, and Environmental Medicine, 62 (11) pp. 1037-1043.
 
Stimuliatsiia vazopressinom gidroliza fasfatidilinozit-4,5-difosfata i ego sviaz' s biosintezom prostaglandinov v épitelii mochevogo puzyria liagushki [Stimulation by vasopressin of hydrolysis of phosphatidylinositol- 4,5-diphosphate and its relation to prostaglandin biosynthesis in the bladder epithelium of frogs].
Parnova R.G., Firsov D.L., 1991. Biulleten' Eksperimental'noĭ Biologii i Meditsiny, 111 (1) pp. 5-7.
 
Uvelichenie gidroosmoticheskogo éffekta vazopressina pri ugnetenii neomitsinom gidroliza fosfatidilinozit-4,5-difosfata [An increase in the hydro-osmotic effect of vasopressin during neomycin suppression of phosphatidylinositol 4,5-diphosphate hydrolysis].
Parnova R.G., Firsov D.L., 1990. Doklady Akademii Nauk SSSR, 310 (4) pp. 1013-1015.
 
Vliianie vazopressina na osmoticheskuiu pronitsaemost' stenki mochevogo puzyria liagushki i soderzhanie v neĭ tsAMF, tsGMF i inozittrifosfat [Effect of vasopressin on the osmotic permeability of the bladder wall in the frog and its content of cAMP, cGMP and inositol triphosphate].
Natochin I.u.V., Parnova R.G., Reznik L.V., Natochin M.I.u., Firsov D.L., 1989. Fiziologicheskii Zhurnal Sssr Imeni I. M. Sechenova, 75 (5) pp. 702-708.
 
Zavisimost' mezhdy vnutrikletochnym soderzhaniem 1-metil-3-izobutilksantina i pronitsaemost'iu dlia vody stenki mochevogo puzyria liagushki [The relationship between the intracellular content of 1-methyl-3-isobutylxanthine and the permeability for water of the bladder wall in the frog].
Natochin I.u.V., Parnova R.G., Firsov D.L., Shakhmatova E.I., Kaminskiĭ I.u.L., 1989. Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova, 75 (12) pp. 1766-1771.
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