Raphaël Genolet

Publications | Phd and Masters theses

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17 publications

In press | 2020 | 2019 | 2018 | 2017 | 2014 | 2013 | 2012 | 2010 | 2005 | 2004 |
 
Disturbed mitochondrial dynamics in CD8<sup>+</sup> TILs reinforce T cell exhaustion.
Yu Y.R., Imrichova H., Wang H., Chao T., Xiao Z., Gao M., Rincon-Restrepo M., Franco F., Genolet R., Cheng W.C. et al. Nature immunology. Peer-reviewed.
 
T-cell repertoire analysis and metrics of diversity and clonality.
Chiffelle J., Genolet R., Perez M.A., Coukos G., Zoete V., Harari A., 2020/09/01. Current opinion in biotechnology, 65 pp. 284-295. Peer-reviewed.
 
High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells.
Costa-Nunes C., Cachot A., Bobisse S., Arnaud M., Genolet R., Baumgaertner P., Speiser D.E., Sousa Alves P.M., Sandoval F., Adotévi O. et al., 2019/07/15. Clinical cancer research, 25 (14) pp. 4320-4331. Peer-reviewed.
 
High-throughput Screening of Human Tumor Antigen–specific CD4 T Cells, Including Neoantigen-reactive T Cells
Costa-Nunes Carla, Cachot Amélie, Bobisse Sara, Arnaud Marion, Genolet Raphael, Baumgaertner Petra, Speiser Daniel E., Sousa Alves Pedro M., Sandoval Federico, Adotévi Olivier et al., 2019/07/15. Clinical Cancer Research, 25 (14) pp. 4320-4331.
 
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer
Tanyi Janos L., Bobisse Sara, Ophir Eran, Tuyaerts Sandra, Roberti Annalisa, Genolet Raphael, Baumgartner Petra, Stevenson Brian J., Iseli Christian, Dangaj Denarda et al., 2018/04/11. Science Translational Medicine, 10 (436) pp. eaao5931.
 
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.
Tanyi J.L., Bobisse S., Ophir E., Tuyaerts S., Roberti A., Genolet R., Baumgartner P., Stevenson B.J., Iseli C., Dangaj D. et al., 2018/04/11. Science translational medicine, 10 (436) pp. NA. Peer-reviewed.
Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.
Bobisse S., Genolet R., Roberti A., Tanyi J.L., Racle J., Stevenson B.J., Iseli C., Michel A., Le Bitoux M.A., Guillaume P. et al., 2018/03/15. Nature communications, 9 (1) p. 1092. Peer-reviewed.
 
Label-free identification of activated T lymphocytes through tridimensional microsensors on chip.
Rollo E., Tenaglia E., Genolet R., Bianchi E., Harari A., Coukos G., Guiducci C., 2017/08/15. Biosensors & bioelectronics, 94 pp. 193-199. Peer-reviewed.
 
Duality of the murine CD8 compartment.
Genolet R., Leignadier J., Osterås M., Farinelli L., Stevenson B.J., Luescher I.F., 2014. Proceedings of the National Academy of Sciences of the United States of America, 111 (11) pp. E1007-E1015.
 
CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire.
Verhagen J., Genolet R., Britton G.J., Stevenson B.J., Sabatos-Peyton C.A., Dyson J., Luescher I.F., Wraith D.C., 2013. Proceedings of the National Academy of Sciences of the United States of America, 110 (3) pp. E221-E230. Peer-reviewed.
 
Highly diverse TCRα chain repertoire of pre-immune CD8(+) T cells reveals new insights in gene recombination.
Genolet R., Stevenson B.J., Farinelli L., Osterås M., Luescher I.F., 2012. Embo Journal, 31 (7) pp. 1666-1678. Peer-reviewed.
 
KAP1 regulates gene networks controlling T-cell development and responsiveness.
Santoni de Sio F.R., Barde I., Offner S., Kapopoulou A., Corsinotti A., Bojkowska K., Genolet R., Thomas J.H., Luescher I.F., Pinschewer D. et al., 2012. FASEB Journal, 26 (11) pp. 4561-4575.
 
The T-cell receptor is not hardwired to engage MHC ligands.
Holland S.J., Bartok I., Attaf M., Genolet R., Luescher I.F., Kotsiou E., Richard A., Wang E., White M., Coe D.J. et al., 2012. Proceedings of the National Academy of Sciences of the United States of America, 109 (45) pp. E3111-E3118. Peer-reviewed.
 
Definition of key variables for the induction of optimal NY-ESO-1-specific T cells in HLA transgene mice.
Johannsen A., Genolet R., Legler D.F., Luther S.A., Luescher I.F., 2010. Journal of Immunology, 185 (6) pp. 3445-3455. Peer-reviewed.
 
Peroxisome proliferator activated receptors
Genolet R., Michalik L., Wahli W., 2005. pp. 267-280 dans Dufour J.F., Clavien P.A., Trautwein C., Graf R. (eds.) Signaling pathways in liver diseases, Springer.
 
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
Genolet R., Kersten S., Braissant O., Mandard S., Tan N.S., Bucher P., Desvergne B., Michalik L., Wahli W., 2005. Journal of Biological Chemistry, 280 (25) pp. 24143-24152. Peer-reviewed.
 
PPARs as drug targets to modulate inflammatory responses?
Genolet R., Wahli W., Michalik L., 2004. Current Drug Targets. Inflammation and Allergy, 3 (4) pp. 361-375. Peer-reviewed.
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