Yvan Arsenijevic

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128 publications

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Fine-tuning FAM161A gene augmentation therapy to restore retinal function.
Arsenijevic Y., Chang N., Mercey O., El Fersioui Y., Koskiniemi-Kuendig H., Joubert C., Bemelmans A.P., Rivolta C., Banin E., Sharon D. et al., 2024/04. EMBO molecular medicine, 16 (4) pp. 805-822. Peer-reviewed.
 
Fine-tuning FAM161A gene augmentation therapy to restore retinal function
Arsenijevic Yvan, Chang Ning, Mercey Olivier, Fersioui Younes El, Koskiniemi-Kuendig Hanna, Joubert Caroline, Bemelmans Alexis-Pierre, Rivolta Carlo, Banin Eyal, Sharon Dror et al., 2023/10/06..
 
Gene augmentation therapy attenuates retinal degeneration in a knockout mouse model of Fam161a retinitis pigmentosa.
Matsevich C., Gopalakrishnan P., Chang N., Obolensky A., Beryozkin A., Salameh M., Kostic C., Sharon D., Arsenijevic Y., Banin E., 2023/10/04. Molecular therapy, 31 (10) pp. 2948-2961. Peer-reviewed.
Lentiviral Vectors for Ocular Gene Therapy.
Arsenijevic Y., Berger A., Udry F., Kostic C., 2022/07/31. Pharmaceutics, 14 (8) p. 1605. Peer-reviewed.
The connecting cilium inner scaffold provides a structural foundation that protects against retinal degeneration.
Mercey O., Kostic C., Bertiaux E., Giroud A., Sadian Y., Gaboriau DCA, Morrison C.G., Chang N., Arsenijevic Y., Guichard P. et al., 2022/06. PLoS biology, 20 (6) pp. e3001649. Peer-reviewed.
Pathogenic Effects of Mineralocorticoid Pathway Activation in Retinal Pigment Epithelium.
Canonica J., Zhao M., Favez T., Gelizé E., Jonet L., Kowalczuk L., Guegan J., Le Menuet D., Viengchareun S., Lombès M. et al., 2021/09/05. International journal of molecular sciences, 22 (17) p. 9618. Peer-reviewed.
Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy.
Mbefo M., Berger A., Schouwey K., Gérard X., Kostic C., Beryozkin A., Sharon D., Dolfuss H., Munier F., Tran H.V. et al., 2021/08/28. International journal of molecular sciences, 22 (17) p. 9331. Peer-reviewed.
 
A new mouse model for retinal degeneration due to Fam161a deficiency.
Beryozkin A., Matsevich C., Obolensky A., Kostic C., Arsenijevic Y., Wolfrum U., Banin E., Sharon D., 2021/01/21. Scientific reports, 11 (1) p. 2030. Peer-reviewed.
 
Pharmacological disruption of the Notch transcription factor complex.
Lehal R., Zaric J., Vigolo M., Urech C., Frismantas V., Zangger N., Cao L., Berger A., Chicote I., Loubéry S. et al., 2020/07/14. Proceedings of the National Academy of Sciences of the United States of America, 117 (28) pp. 16292-16301. Peer-reviewed.
Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures.
Decembrini S., Hoehnel S., Brandenberg N., Arsenijevic Y., Lutolf M.P., 2020/06/24. Scientific reports, 10 (1) p. 10275. Peer-reviewed.
Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level.
Udry F., Decembrini S., Gamm D.M., Déglon N., Kostic C., Arsenijevic Y., 2020/06/01. Scientific reports, 10 (1) p. 8890. Peer-reviewed.
 
An in vitro Model of Human Retinal Detachment Reveals Successive Death Pathway Activations.
Potic J., Mbefo M., Berger A., Nicolas M., Wanner D., Kostic C., Matet A., Behar-Cohen F., Moulin A., Arsenijevic Y., 2020. Frontiers in neuroscience, 14 p. 571293. Peer-reviewed.
CFH exerts anti-oxidant effects on retinal pigment epithelial cells independently from protecting against membrane attack complex.
Borras C., Canonica J., Jorieux S., Abache T., El Sanharawi M., Klein C., Delaunay K., Jonet L., Salvodelli M., Naud M.C. et al., 2019/09/25. Scientific reports, 9 (1) p. 13873. Peer-reviewed.
Gene Transfer with AAV9-PHP.B Rescues Hearing in a Mouse Model of Usher Syndrome 3A and Transduces Hair Cells in a Non-human Primate.
György B., Meijer E.J., Ivanchenko M.V., Tenneson K., Emond F., Hanlon K.S., Indzhykulian A.A., Volak A., Karavitaki K.D., Tamvakologos P.I. et al., 2019/06/14. Molecular therapy. Methods & clinical development, 13 pp. 1-13. Peer-reviewed.
 
The Evaluation of BMI1 Posttranslational Modifications During Retinal Degeneration to Understand BMI1 Action on Photoreceptor Death Execution.
Mbefo M.K., Arsenijevic Y., 2018. Advances in experimental medicine and biology, 1074 pp. 359-365. Peer-reviewed.
Evaluation of tolerance to lentiviral LV-RPE65 gene therapy vector after subretinal delivery in non-human primates.
Matet A., Kostic C., Bemelmans A.P., Moulin A., Rosolen S.G., Martin S., Mavilio F., Amirjanians V., Stieger K., Lorenz B. et al., 2017/10. Translational research, 188 pp. 40-57.e4. Peer-reviewed.
ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy.
Rothschild P.R., Salah S., Berdugo M., Gélizé E., Delaunay K., Naud M.C., Klein C., Moulin A., Savoldelli M., Bergin C. et al., 2017/08/18. Scientific reports, 7 (1) p. 8834. Peer-reviewed.
Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration.
Kruczek K., Gonzalez-Cordero A., Goh D., Naeem A., Jonikas M., Blackford SJI, Kloc M., Duran Y., Georgiadis A., Sampson R.D. et al., 2017/06/06. Stem cell reports, 8 (6) pp. 1659-1674. Peer-reviewed.
Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development.
Minocha S., Valloton D., Arsenijevic Y., Cardinaux J.R., Guidi R., Hornung J.P., Lebrand C., 2017/03/07. Scientific reports, 7 p. 43093. Peer-reviewed.
Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation.
Decembrini S., Martin C., Sennlaub F., Chemtob S., Biel M., Samardzija M., Moulin A., Behar-Cohen F., Arsenijevic Y., 2017/03/01. Molecular therapy : the journal of the American Society of Gene Therapy, 25 (3) pp. 634-653. Peer-reviewed.
Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.
Toffoli B., Gilardi F., Winkler C., Soderberg M., Kowalczuk L., Arsenijevic Y., Bamberg K., Bonny O., Desvergne B., 2017. PLoS One, 12 (2) pp. e0171474. Peer-reviewed.
Rai1 frees mice from the repression of active wake behaviors by light.
Diessler S., Kostic C., Arsenijevic Y., Kawasaki A., Franken P., 2017. eLife, 6 pp. e23292. Peer-reviewed.
Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration.
Sahaboglu A., Barth M., Secer E., Amo E.M., Urtti A., Arsenijevic Y., Zrenner E., Paquet-Durand F., 2016/12/22. Scientific reports, 6 p. 39537. Peer-reviewed.
 
HDAC inhibition in the cpfl1 mouse protects degenerating cone photoreceptors in vivo.
Trifunović D., Arango-Gonzalez B., Comitato A., Barth M., Del Amo E.M., Kulkarni M., Sahaboglu A., Hauck S.M., Urtti A., Arsenijevic Y. et al., 2016/10/15. Human molecular genetics, 25 (20) pp. 4462-4472. Peer-reviewed.
Mutations in CEP78 Cause Cone-Rod Dystrophy and Hearing Loss Associated with Primary-Cilia Defects.
Nikopoulos K., Farinelli P., Giangreco B., Tsika C., Royer-Bertrand B., Mbefo M.K., Bedoni N., Kjellström U., El Zaoui I., Di Gioia S.A. et al., 2016/09/01. American journal of human genetics, 99 (3) pp. 770-776. Peer-reviewed.
Nkx2.1 regulates the proliferation and cell fate of telencephalic astrocytes during embryonic development
Minocha S, Valloton D, Arsenijevic Y, Cardinaux J-R, Dreier Guidi R, Hornung J-P, Lebrand C, 2016/07..
Amyloid Precursor-Like Protein 2 deletion-induced retinal synaptopathy related to congenital stationary night blindness: structural, functional and molecular characteristics.
Dinet V., Ciccotosto G.D., Delaunay K., Borras C., Ranchon-Cole I., Kostic C., Savoldelli M., El Sanharawi M., Jonet L., Pirou C. et al., 2016/06/08. Molecular brain, 9 (1) p. 64. Peer-reviewed.
Determination of Rod and Cone Influence to the Early and Late Dynamic of the Pupillary Light Response.
Kostic C., Crippa S.V., Martin C., Kardon R.H., Biel M., Arsenijevic Y., Kawasaki A., 2016/05. Investigative Ophthalmology and Visual Science, 57 (6) pp. 2501-2508. Peer-reviewed.
Animal modelling for inherited central vision loss.
Kostic C., Arsenijevic Y., 2016. Journal of Pathology, 238 (2) pp. 300-310. Peer-reviewed.
 
Cell Cycle Proteins and Retinal Degeneration: Evidences of New Potential Therapeutic Targets.
Arsenijevic Y., 2016. Advances In Experimental Medicine and Biology, 854 pp. 371-377. Peer-reviewed.
An Advocacy for the Use of 3D Stem Cell Culture Systems for the Development of Regenerative Medicine: An Emphasis on Photoreceptor Generation
Arsenijevic Yvan , Decembrini Sarah , 2015. Journal of Stem Cell Research & Therapy, 05 (07) pp. 1-10. Peer-reviewed.
Interactome analysis reveals that FAM161A, deficient in recessive retinitis pigmentosa, is a component of the Golgi-centrosomal network.
Di Gioia S.A., Farinelli P., Letteboer S.J., Arsenijevic Y., Sharon D., Roepman R., Rivolta C., 2015. Human Molecular Genetics, 24 (12) pp. 3359-3371. Peer-reviewed.
Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors.
Askou A.L., Aagaard L., Kostic C., Arsenijevic Y., Hollensen A.K., Bek T., Jensen T.G., Mikkelsen J.G., Corydon T.J., 2015. Molecular Therapy. Methods and Clinical Development, 2 p. 14064. Peer-reviewed.
 
Construction and Quantitative Evaluation of a Dual Specific Promoter System for Monitoring the Expression Status of Stra8 and c-kit Genes.
Dastpak M., Matin M.M., Farshchian M., Arsenijevic Y., Momeni-Moghaddam M., Sisakhtnezhad S., Boozarpour S., Bidkhori H.R., Mirahmadi M., Bahrami A.R., 2014. Molecular Biotechnology, 56 (12) pp. 1100-1109. Peer-reviewed.
Derivation of traceable and transplantable photoreceptors from mouse embryonic stem cells.
Decembrini S., Koch U., Radtke F., Moulin A., Arsenijevic Y., 2014. Stem Cell Reports, 2 (6) pp. 853-865. Peer-reviewed.
 
Notch signaling in the pigmented epithelium of the anterior eye segment promotes ciliary body development at the expense of iris formation.
Sarode B., Nowell C.S., Ihm J., Kostic C., Arsenijevic Y., Moulin A.P., Schorderet D.F., Beermann F., Radtke F., 2014. Pigment Cell and Melanoma Research, 27 (4) pp. 580-589. Peer-reviewed.
Hyperactivation of retina by light in mice leads to photoreceptor cell death mediated by VEGF and retinal pigment epithelium permeability.
Cachafeiro M., Bemelmans A.P., Samardzija M., Afanasieva T., Pournaras J.A., Grimm C., Kostic C., Philippe S., Wenzel A., Arsenijevic Y., 2013. Cell Death and Disease, 4 pp. e781. Peer-reviewed.
Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy.
Kostic C., Lillico S.G., Crippa S.V., Grandchamp N., Pilet H., Philippe S., Lu Z., King T.J., Mallet J., Sarkis C. et al., 2013. Plos One, 8 (8) pp. e71363. Peer-reviewed.
 
Retinal degeneration depends on Bmi1 function and reactivation of cell cycle proteins.
Zencak D., Schouwey K., Chen D., Ekström P., Tanger E., Bremner R., van Lohuizen M., Arsenijevic Y., 2013. Proceedings of the National Academy of Sciences of the United States of America, 110 pp. E593-E601.. Peer-reviewed.
ROCK Inhibitor Enhances Adhesion and Wound Healing of Human Corneal Endothelial Cells.
Pipparelli A., Arsenijevic Y., Thuret G., Gain P., Nicolas M., Majo F., 2013. Plos One, 8 (4) pp. e62095. Peer-reviewed.
 
Analysis of photoreceptor abnormality in GUCY2D E837D/R838S transgenic pigs
Kostic C., King T., Crippa S., Philippe S., Lillico S., Sarkis C., Mallet J., Arsenijevic Y., Whitelaw B., 2012., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 6462/A388. Peer-reviewed.
Caveolin-1 opens endothelial cell junctions by targeting catenins.
Kronstein R., Seebach J., Grossklaus S., Minten C., Engelhardt B., Drab M., Liebner S., Arsenijevic Y., Taha A.A., Afanasieva T. et al., 2012. Cardiovascular Research, 93 (1) pp. 130-140. Peer-reviewed.
 
Dual role of Bmi1 loss in the preservation of photoreceptor layers in the Rd1 mouse
Schouwey K., Zencak D., Van Lohuizen M., Arsenijevic Y., 2012., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 330/A571. Peer-reviewed.
 
FAM161A, associated with autosomal recessive retinitis pigmentosa,localizes at the level of the photoreceptor cilium and interacts with proteins involved in ciliopathies
Di Gioia S.A., Kostic C., Letteboer S.J.F., Hetterschijt L., Arsenijevic Y., Roepman R., Rivolta C., 2012., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 1732. Peer-reviewed.
FAM161A, associated with retinitis pigmentosa, is a component of the cilia-basal body complex and interacts with proteins involved in ciliopathies.
Di Gioia S.A., Letteboer S.J., Kostic C., Bandah-Rozenfeld D., Hetterschijt L., Sharon D., Arsenijevic Y., Roepman R., Rivolta C., 2012. Human Molecular Genetics, 21 (23) pp. 5174-5184. Peer-reviewed.
 
Lentiviral-directed transgenesis in swine is an efficient tool to study human dominant genetic diseases
Kostic C., Grandchamp N., King T., Crippa S., Philippe S., Lillico S., Sarkis C., Mallet J., Arsenijevic Y., Whitelaw B., 2012. pp. A147 dans Collaborative Congress of the European Society of Gene and Cell Therapy/French Society of Cell and Gene Therapy, Human Gene Therapy.
 
Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.
Askou A.L., Pournaras J.A., Pihlmann M., Svalgaard J.D., Arsenijevic Y., Kostic C., Bek T., Dagnaes-Hansen F., Mikkelsen J.G., Jensen T.G. et al., 2012. Journal of Gene Medicine, 14 (11) pp. 632-641. Peer-reviewed.
 
Role of glast-positive glial cells during photoreceptor development
Decembrini S., Arsenijevic Y, 2012., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 3964/D828. Peer-reviewed.
 
Use of a short hPDE6b promoter for rod gene transfer in a model of severe retinal cystrophy, the Rd10 mouse
Arsenijevic Y., Kostic C., Auricchio A., Ihm J., 2012., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 1925/D742. Peer-reviewed.
 
Characterization Of Cdk Expressions During Retinal Degeneration In Rd1 Mice
Schouwey K., Arsenijevic Y., 2011., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 1832/A362. Peer-reviewed.
 
Deleterious Actions Of Vegf On The Blood Retinal Barrier And Photoreceptor Survival In The Light-damage Model
Cachafeiro M., Bemelmans A.P., Samardzija M., Wenzel A., Grimm C., Arsenijevic Y., 2011., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 1848/A378. Peer-reviewed.
 
Establishment of a reliable laser-Induced Choroidal Neovascularization Animal Model
Pournaras J.A.C., Cachafeiro M., Pignat V., Arsenijevic Y., 2011., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 944/A136. Peer-reviewed.
Gene therapy regenerates protein expression in cone photoreceptors in Rpe65(R91W/R91W) mice.
Kostic C., Crippa S.V., Pignat V., Bemelmans A.P., Samardzija M., Grimm C., Wenzel A., Arsenijevic Y., 2011. Plos One, 6 (2) pp. e16588. Peer-reviewed.
 
Mice Transgenic For Human Dominant Mutations Of The GUCY2D Gene
Kostic C., Pignat V., Whitelaw B., Pilet H., Ursulet S., Dussaud S., Arsenijevic Y., Sarkis C., 2011., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 4343/D1087. Peer-reviewed.
 
Optimization Of Promoter Sequences In Order To Mimic Physiological Pde6b Expression
Ihm J.E., Auricchio A., Arsenijevic Y., 2011., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 23/A14. Peer-reviewed.
 
Pigs Transgenic For Human Dominant Mutations Of The GUCY2D Gene
Arsenijevic Y., King T., Crippa S.V., Lillico S., Sarkis C., Mallet J., Kostic C., Whitelaw B., 2011., Association for Research in Vision and Ophthalmology dans ARVO E-Abstract 4340/D1084. Peer-reviewed.
 
Reduced choroidal neovascularization by AAV-anti-VEGF shRNA delivery
Askou A. L., Pihlmann M., Pournaras J. C., Arsenijevic Y., Kostic C., Bek T., Dagnaes-Hansen F., Mikkelsen J. G., Jensen T. G., Corydon T. J., 2011. pp. A75 dans European Society of Gene and Cell Therapy British Society for Gene Therapy Collaborative Congress 2011, Human gene therapy. Peer-reviewed.
Retinal degeneration progression changes lentiviral vector cell targeting in the retina.
Calame M., Cachafeiro M., Philippe S., Schouwey K., Tekaya M., Wanner D., Sarkis C., Kostic C., Arsenijevic Y., 2011. Plos One, 6 (8) pp. e23782.
 
Use of human MAR elements to improve retroviral vector production.
Buceta M., Galbete J.L., Kostic C., Arsenijevic Y., Mermod N., 2011. Gene Therapy, 18 (1) pp. 7-13. Peer-reviewed.
 
Nonsense Mutations in FAM161A Cause RP28-Associated Recessive Retinitis Pigmentosa.
Langmann T., Di Gioia S.A., Rau I., Stöhr H., Maksimovic N.S., Corbo J.C., Renner A.B., Zrenner E., Kumaramanickavel G., Karlstetter M. et al., 2010/09. American Journal of Human Genetics, 87 (3) pp. 376-381. Peer-reviewed.
 
Cell Adhesion Peptide RGDSP and Laminin Support Proliferation and Migration of Postnatal Retinal Stem Cells in a 3D Hydrogel Culture System
Djojosubroto M.W., Eberhardt M., Kraehenbuehl T.P., Tekaya M., Lutolf M.P., Hubbell J.A., Arsenijevic Y., 2010., ARVO E-Abstract 1878/D759 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
 
Inhibition of Notch Pathway Enhances Photoreceptor Commitment From Cultured Retinal Stem Cells
Montavon P., Arsenijevic Y., 2010., ARV E-Abstract 2645/A452 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
 
Lentiviral Vector Tropism In Degenerating Retinas
Calame M., Tekaya M., Maillard A., Cachafeiro M., Philippe S., Sarkis C., Mallet J., Kostic C., Arsenijevic Y., 2010., ARVO E-Abstract 4502/A474 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
Remaining rod activity mediates visual behavior in adult Rpe65-/- mice.
Cachafeiro M., Bemelmans A.P., Canola K., Pignat V., Crippa S.V., Kostic C., Arsenijevic Y., 2010. Investigative Ophthalmology and Visual Science, 51 (12) pp. 6835-6842. Peer-reviewed.
 
Rpe65-Gene Transfer Using an Integration-Deficient Lentiviral Vector
Kostic C., Philippe S., Crippa S., Samardzija M., Pignat V., Wanner D., Grimm C., Sarkis C., Mallet J., Arsenijevic Y., 2010., ARVO E-Abstract 4498/A470 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
 
Stem Cell Transplantation for Retinal Degenerations
Arsenijevic Y., 2010., ARVO E-Abstract 881 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
 
3D culture of postnatal retinal stem cells using self assembling polymers
Arsenijevic Y., Eberhardt M., Kraehenbuehl T.P., Tekaya M., Lutolf M., Hubbell J.A., 2009., ARVO E-Abstract 5152 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
 
Chromosomal number aberrations and transformation in adult mouse retinal stem cells in vitro.
Djojosubroto Meta, Bollotte Frederic, Wirapati Pratyaksha, Radtke Freddy, Stamenkovic Ivan, Arsenijevic Yvan, 2009. Investigative Ophthalmology & Visual Science, 50 (12) pp. 5975-5987.
 
Comparison of visual preservation after transplantation of BDNF or GDNF secreting mesenchymal stem cells in glaucomatous rat eyes
Harper M.M., Sakaguchi D.S., Kuehn M.H., Kwon Y.H., Kardon R.H., Bemelmans A., Kostic C., Arsenijevic Y., Grozdanic S.C., 2009., ARVO E-Abstract 2754 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
 
Efficient lentiviral gene transfer into corneal stroma cells using a femtosecond laser.
Bemelmans A.P., Arsenijevic Y., Majo F., 2009. Gene Therapy, 16 (7) pp. 933-938. Peer-reviewed.
In conditions of limited chromophore supply rods entrap 11-cis-retinal leading to loss of cone function and cell death.
Samardzija M., Tanimoto N., Kostic C., Beck S., Oberhauser V., Joly S., Thiersch M., Fahl E., Arsenijevic Y., von Lintig J. et al., 2009. Human molecular genetics, 18 (7) pp. 1266-75. Peer-reviewed.
 
Increased therapeutic window for the R91W mutant form of Rpe65 compared to Rpe65 null backgroud
Kostic C., Bemelmans A.P., Crippa S., Samardzija M., Pignat V., Tekaya M., Wanner D., Wenzel A., Arsenijevic Y., 2009., ARVO E-Abstract 1743 dans Investigative ophthalmology and visual science. Peer-reviewed.
 
Non integrative lentiviral vactors for gene transfer in the retina
Philippe S., Arsenijevic Y., Kostic C., Serguera C., Mallet J., Sarkis C., 2009., ARVO E-Abstract 3024 dans Investigative ophthalmology and visual science. Peer-reviewed.
 
Novel relationship between Vegf expression and retinal pigmented epithelium permeability following light damage in the mouse retina
Cachafeiro M., Bemelmans A.P., Kostic C., Samardzija M., Tekaya M., Wanner D., Wenzel A., Arsenijevic Y., 2009., ARVO E-Abstract 3524 dans Investigative Ophthalmology and Visual Science. Peer-reviewed.
Ophtalmologie. Thérapie génique des rétinopathies héréditaires: premiers résultats [Gene therapy for hereditary eye diseases: where are we?]
Viet Tran H., Schorderet D.F., Kostic C., Munier F.L., Arsenijevic Y., 2009. Revue Médicale Suisse, 5 (186) pp. 118-123.
The fetal hypothalamus has the potential to generate cells with a gonadotropin releasing hormone (GnRH) phenotype.
Salvi R., Arsenijevic Y., Giacomini M., Rey J.P., Voirol M.J., Gaillard R.C., Risold P.Y., Pralong F., 2009. PloS one, 4 (2) pp. e4392. Peer-reviewed.
 
Lentiviral gene transfer-mediated cone vision restoration in RPE65 knockout mice.
Bemelmans A.P., Kostic C., Cachafeiro M., Crippa S.V., Wanner D., Tekaya M., Wenzel A., Arsenijevic Y., 2008. Advances In Experimental Medicine and Biology, 613 pp. 89-95. Peer-reviewed.
Overexpression of a mutant form of TGFBI/BIGH3 induces retinal degeneration in transgenic mice.
Bustamante M., Tasinato A., Maurer F., Elkochairi I., Lepore M.G., Arsenijevic Y., Pedrazzini T., Munier F.L., Schorderet D.F., 2008. Molecular Vision, 14 pp. 1129-1137. Peer-reviewed.
Retinal stem cells: promising candidates for retina transplantation.
Djojosubroto M.W., Arsenijevic Y., 2008. Cell and Tissue Research, 331 (1) pp. 347-357.
When green algae give light to blind mice
Arsenijevic Y., Kostic C., 2008. p. 55 dans Abstract, Cellscience. Peer-reviewed.
 
Generation of cells committed towards the photoreceptor fate for retinal transplantation
Canola K., Arsenijevic Y., 2007/06. Neuroreport, 18 (9) pp. 851-5.
 
Development of in vitro and in vivo models to study retinal stem cell biology.
Angénieux B., Canola K., Zencak D., Arsenijevic Y., 2007/03/02. Swiss medical weekly, 137 (Suppl 155) pp. 39S-43S. Peer-reviewed.
Retinal stem cells transplanted into models of late stages of retinitis pigmentosa preferentially adopt a glial or a retinal ganglion cell fate
Canola K., Angenieux B., Tekaya M., Quiambao A., Naash M. I., Munier F. L., Schorderet D. F., Arsenijevic Y., 2007/01. Investigative Ophthalmology and Visual Science, 48 (1) pp. 446-54. Peer-reviewed.
 
Towards therapeutic applications of ocular stem cells.
Pelligrini G de Luca M Arsenijevic Y, 2007. Semin Cell Dev Biol, 18 pp. 805-18. Peer-reviewed.
 
High yield of cells committed to the photoreceptor fate from expanded mouse retinal stem cells
Merhi-Soussi F., Angenieux B., Canola K., Kostic C., Tekaya M., Hornfeld D., Arsenijevic Y., 2006/09. Stem Cells, 24 (9) pp. 2060-70.
Phenotype of three consanguineous Tunisian families with early-onset retinal degeneration caused by an R91W homozygous mutation in the RPE65 gene.
El Matri L., Ambresin A., Schorderet D.F., Kawasaki A., Seeliger M.W., Wenzel A., Arsenijevic Y., Borruat F.X., Munier F.L., 2006/09. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie, 244 (9) pp. 1104-12. Peer-reviewed.
 
Epidermal growth factor is a neuronal differentiation factor for retinal stem cells in vitro
Angenieux B., Schorderet D. F., Arsenijevic Y., 2006/03. Stem Cells, 24 (3) pp. 696-706.
 
BMI1 loss delays photoreceptor degeneration in Rd1 mice. Bmi1 loss and neuroprotection in Rd1 mice
Zencak D., Crippa S. V., Tekaya M., Tanger E., Schorderet D. E., Munier F. L., van Lohuizen M., Arsenijevic Y., 2006. Advances in Experimental Medicine and Biology, 572 pp. 209-15.
Lentiviral gene transfer of RPE65 rescues survival and function of cones in a mouse model of Leber congenital amaurosis.
Bemelmans A.P., Kostic C., Crippa S.V., Hauswirth W.W., Lem J., Munier F.L., Seeliger M.W., Wenzel A., Arsenijevic Y., 2006. PLoS Medicine, 3 (10) pp. e347. Peer-reviewed.
 
Lentiviral vectors containing a retinal pigment epithelium specific promoter for leber congenital amaurosis gene therapy. Lentiviral gene therapy for LCA
Bemelmans A. P., Kostic C., Hornfeld D., Jaquet M., Crippa S. V., Hauswirth W. W., Lem J., Wang Z., Schorderet D. E., Munier F. L. et al., 2006. Advances in Experimental Medicine and Biology, 572 pp. 247-53.
 
Microarray analysis reveals retinal stem cell characteristics of the adult human eye. For contributed volumes
Angenieux B., Michaut L., Schorderet D. E., Munier F. L., Gehring W., Arsenijevic Y., 2006. Advances in Experimental Medicine and Biology, 572 pp. 377-80.
 
D-TAT transporter as an ocular peptide delivery system
Schorderet D. F., Manzi V., Canola K., Bonny C., Arsenijevic Y., Munier F. L., Maurer F., 2005/12. Clinical and Experimental Ophthalmology, 33 (6) pp. 628-35.
 
CNS regeneration: a morphogen's tale
Vergara M. N., Arsenijevic Y., Del Rio-Tsonis K., 2005/09. Journal of Neurobiology, 64 (4) pp. 491-507.
Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation
Zencak D., Lingbeek M., Kostic C., Tekaya M., Tanger E., Hornfeld D., Jaquet M., Munier F. L., Schorderet D. F., van Lohuizen M. et al., 2005/06. Journal of Neuroscience, 25 (24) pp. 5774-83.
 
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice
Bruggeman S. W., Valk-Lingbeek M. E., van der Stoop P. P., Jacobs J. J., Kieboom K., Tanger E., Hulsman D., Leung C., Arsenijevic Y., Marino S. et al., 2005/06. Genes and Development, 19 (12) pp. 1438-43.
 
Future perspectives: from stem cells and IGF biology to the clinic
Arsenijevic Y., 2005. Advances in Experimental Medicine and Biology, 567 pp. 385-412.
 
Lentiviral vector-mediated gene transfer in adult mouse photoreceptors is impaired by the presence of a physical barrier.
Grüter O., Kostic C., Crippa S.V., Perez M.T., Zografos L., Schorderet D.F., Munier F.L., Arsenijevic Y., 2005. Gene therapy, 12 (11) pp. 942-947. Peer-reviewed.
 
Facile isolation and the characterization of human retinal stem cells
Coles B. L., Angenieux B., Inoue T., Del Rio-Tsonis K., Spence J. R., McInnes R. R., Arsenijevic Y., van der Kooy D., 2004/11. Proceedings of the National Academy of Sciences of the United States of America, 101 (44) pp. 15772-7.
 
NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes.
Cui X.Y., Hu Q.D., Tekaya M., Shimoda Y., Ang B.T., Nie D.Y., Sun L., Hu W.P., Karsak M., Duka T. et al., 2004/06. Journal of Biological Chemistry, 279 (24) pp. 25858-25865. Peer-reviewed.
 
Induction of apoptosis in human corneal and HeLa cells by mutated BIGH3
Morand S., Buchillier V., Maurer F., Bonny C., Arsenijevic Y., Munier F. L., Schorderet D. F., 2003/07. Investigative Ophthalmology and Visual Science, 44 (7) pp. 2973-9.
Mammalian neural stem-cell renewal: nature versus nurture
Arsenijevic Y., 2003/02. Molecular Neurobiology, 27 (1) pp. 73-98.
 
Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina.
Kostic C., Chiodini F., Salmon P., Wiznerowicz M., Deglon N., Hornfeld D., Trono D., Aebischer P., Schorderet D.F., Munier F.L. et al., 2003. Gene Therapy, 10 (9) pp. 818-821.
 
Cerveau et régénérescence
Arsenijevic Y., 2003. dans Symposium Vie et mort des neurones, semaine du cerveau, Schweizer Archiv für Neurologie und Psychiatrie.
 
Delivery of ciliary neurotrophic factor via lentiviral-mediated transfer protects axotomized retinal ganglion cells for an extended period of time.
van Adel B.A., Kostic C., Déglon N., Ball A.K., Arsenijevic Y., 2003. Human Gene Therapy, 14 (2) pp. 103-115.
 
Non-neural regions of the adult human eye: a potential source of neurons?
Arsenijevic Y., Taverney N., Kostic C., Tekaya M., Riva F., Zografos L., Schorderet D., Munier F., 2003. Investigative Ophthalmology and Visual Science, 44 (2) pp. 799-807. Peer-reviewed.
 
Aberrant accumulation of EFEMP1 underlies drusen formation in Malattia Leventinese and age-related macular degeneration
Marmorstein L. Y., Munier F. L., Arsenijevic Y., Schorderet D. F., McLaughlin P. J., Chung D., Traboulsi E., Marmorstein A. D., 2002/10. Proceedings of the National Academy of Sciences of the United States of America, 99 (20) pp. 13067-72.
 
A novel method for in vitro production of human glial-like cells from neurosurgical resection tissue
Brunet J. F., Pellerin L., Arsenijevic Y., Magistretti P., Villemure J. G., 2002/06. Lab Invest, 82 (6) pp. 809-12. Peer-reviewed.
 
BIGH3 mutation spectrum in corneal dystrophies.
Munier F.L., Frueh B.E., Othenin-Girard P., Uffer S., Cousin P., Wang M.X., Héon E., Black G.C., Blasi M.A., Balestrazzi E. et al., 2002. Investigative Ophthalmology and Visual Science, 43 (4) pp. 949-954.
Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2
Arsenijevic Y., Weiss S., Schneider B., Aebischer P., 2001/09. Journal of Neuroscience, 21 (18) pp. 7194-202.
 
Isolation of multipotent neural precursors residing in the cortex of the adult human brain
Arsenijevic Y., Villemure J. G., Brunet J. F., Bloch J. J., Deglon N., Kostic C., Zurn A., Aebischer P., 2001/07. Experimental Neurology, 170 (1) pp. 48-62. Peer-reviewed.
 
Differential roles of tumor necrosis factor-alpha and interferon-gamma in mouse hypermetabolic and anorectic responses induced by LPS
Arsenijevic D., Garcia I., Vesin C., Vesin D., Arsenijevic Y., Seydoux J., Girardier L., Ryffel B., Dulloo A., Richard D., 2000/12. European Cytokine Network, 11 (4) pp. 662-8.
 
Les origines des neurones chez l 'adulte
Represa A., Arsenijevic Y., 2000. La Recherche, 329 pp. 35-38.
 
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease.
Déglon N., Tseng J.L., Bensadoun J.C., Zurn A.D., Arsenijevic Y., Pereira de Almeida L., Zufferey R., Trono D., Aebischer P., 2000. Human Gene Therapy, 11 (1) pp. 179-190.
 
A role for the POU-III transcription factor Brn-4 in the regulation of striatal neuron precursor differentiation
Shimazaki T., Arsenijevic Y., Ryan A. K., Rosenfeld M. G., Weiss S., 1999/01. EMBO Journal, 18 (2) pp. 444-56.
 
Insulin-like growth factor-I is a differentiation factor for postmitotic CNS stem cell-derived neuronal precursors: distinct actions from those of brain-derived neurotrophic factor.
Arsenijevic Y., Weiss S., 1998/03. Journal of Neuroscience, 18 (6) pp. 2118-2128.
 
Region-specific effect of testosterone on oxytocin receptor binding in the brain of the aged rat
Arsenijevic Y., Tribollet E., 1998/02. Brain Research, 785 (1) pp. 167-70.
 
Vasopressin binding sites in the central nervous system: distribution and regulation
Tribollet E., Arsenijevic Y., Barberis C., 1998. Progress in Brain Research, 119 pp. 45-55.
 
Distribution of vasopressin and oxytocin receptors in the rat spinal cord: sex-related differences and effect of castration in pudendal motor nuclei
Tribollet E., Barberis C., Arsenijevic Y., 1997/05. Neuroscience, 78 (2) pp. 499-509.
 
Vasopressin potentiation of the melatonin synthetic pathway via specific V1a receptors in the rat pineal gland
Simonneaux V., Kozak R., Arsenijevic Y., Pevet P., 1996/01. Regulatory Peptides, 61 (1) pp. 63-9.
 
Reduced binding of oxytocin in the rat brain during aging
Arsenijevic Y., Dreifuss J. J., Vallet P., Marguerat A., Tribollet E., 1995/11. Brain Research, 698 (1-2) pp. 275-9.
 
Characterization of a novel, linear radioiodinated vasopressin antagonist: an excellent radioligand for vasopressin V1a receptors
Barbeis C., Balestre M. N., Jard S., Tribollet E., Arsenijevic Y., Dreifuss J. J., Bankowski K., Manning M., Chan W. Y., Schlosser S. S. et al., 1995/08. Neuroendocrinology, 62 (2) pp. 135-46.
 
Axotomy induces the expression of vasopressin receptors in cranial and spinal motor nuclei in the adult rat
Tribollet E., Arsenijevic Y., Marguerat A., Barberis C., Dreifuss J. J., 1994/09. Proceedings of the National Academy of Sciences of the United States of America, 91 (20) pp. 9636-40.
 
Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor does not disturb the course of sexual maturation and fertility in the female rat
Gruaz N. M., Arsenijevic Y., Wehrenberg W. B., Sizonenko P. C., Aubert M. L., 1994/08. Endocrinology, 135 (2) pp. 509-19.
 
Vasopressin-binding sites in the pig pituitary gland: competition by novel vasopressin antagonists suggests the existence of an unusual receptor subtype in the anterior lobe
Arsenijevic Y., Dubois-Dauphin M., Tribollet E., Manning M., Sawyer W. H., Dreifuss J. J., 1994/06. Journal of Endocrinology, 141 (3) pp. 383-91.
 
Mécanismes d'action de la gonadolibérine au niveau des cellules gonadotropes hypophysaires [Mechanism of action of gonadoliberin in pituitary gonadotropic cells]
Arsenijevic Y., Aubert M.L., 1990. Annales d'Endocrinologie, 51 (2) pp. 65-71. Peer-reviewed.
 
Growth hormone (GH) deprivation induced by passive immunization against rat GH-releasing factor delays sexual maturation in the male rat
Arsenijevic Y., Wehrenberg W. B., Conz A., Eshkol A., Sizonenko P. C., Aubert M. L., 1989/06. Endocrinology, 124 (6) pp. 3050-9.
 
Plasma growth hormone (GH) response to intravenous GH-releasing factor (GRF) in adult rats: evidence for transient pituitary desensitization after GRF stimulation
Arsenijevic Y., Rivest R. W., Eshkol A., Sizonenko P. C., Aubert M. L., 1987/10. Endocrinology, 121 (4) pp. 1487-96.
 
Activation of the hypothalamo-neurohypophysial system by hypertonic superfusion of the rat mesentery
Arsenijevic Y., Baertschi A. J., 1985/11. Brain Research, 347 (1) pp. 169-72.
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