Jean-Pierre Mach

Publications | Mémoires et thèses

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217 publications

2018 | 2017 | 2016 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990 | 1989 | 1988 | 1987 | 1986 | 1985 | 1984 | 1983 | 1982 | 1981 | 1980 | 1979 | 1978 | 1977 | 1976 | 1975 | 1974 | 1973 | ...
CART cells are prone to Fas- and DR5-mediated cell death.
Tschumi B.O., Dumauthioz N., Marti B., Zhang L., Lanitis E., Irving M., Schneider P., Mach J.P., Coukos George, Romero P. et al., 2018/07/13. Journal for immunotherapy of cancer, 6 (1) p. 71. Peer-reviewed.
 
Analysis of cytokine immune response profile in response to inflammatory stimuli in mice with genetic defects in fetal and adult hemoglobin chain expression.
Khatri I., Alexander C., Brandenburg K., Chen Z., Heini A., Heumann D., Mach J.P., Mazzoli V., Rietschel E., Terskikh A. et al., 2018/07. The pharmacogenomics journal, 18 (4) pp. 546-555. Peer-reviewed.
 
Corrigendum to "An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression" [Int. Immunopharmacol. 50 (2017) 69-76].
Gorczynski R.M., Alexander C., Brandenburg K., Chen Z., Heini A., Neumann D., Mach J.P., Rietschel E.T., Terskikh A., Ulmer A.J. et al., 2018/06. International immunopharmacology, 59 p. 414. Peer-reviewed.
 
Corrigendum to "Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis" [Int. Immunopharmacol. 57 (2018) 112-120].
Kos O., Alexander C., Brandenburg K., Chen Z., Heini A., Heumann D., Khatri I., Mach J.P., Rietschel E.T., Terskikh A. et al., 2018/06. International immunopharmacology, 59 p. 413. Peer-reviewed.
Correction to: CART cells are prone to Fas- and DR5-mediated cell death.
Tschumi B.O., Dumauthioz N., Marti B., Zhang L., Lanitis E., Irving M., Schneider P., Mach J.P., Coukos G., Romero P. et al., 2018. Journal for Immunotherapy of Cancer, 6 (1) p. 92. Peer-reviewed.
 
Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis.
Kos O., Alexander C., Brandenburg K., Chen Z., Heini A., Heumann D., Khatri I., Mach J.P., Rietschel E.T., Tersikh A. et al., 2018. International Immunopharmacology, 57 pp. 112-120. Peer-reviewed.
 
An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression.
Gorczynski R.M., Alexander C., Brandenburg K., Chen Z., Heini A., Neumann D., Mach J.P., Rietschel E.T., Tersikh A., Ulmer A.J. et al., 2017/09. International immunopharmacology, 50 pp. 69-76. Peer-reviewed.
 
[Recombinant Monoclonal Antibodies, from Tumor Targeting to Cancer Immunotherapy: A Critical Overview].
Mach J.P., 2017. Molekuliarnaia biologiia, 51 (6) pp. 1024-1038. Peer-reviewed.
 
Design and Validation of a Novel Generic Platform for the Production of Tetravalent IgG1-like Bispecific Antibodies.
Golay J., Choblet S., Iwaszkiewicz J., Cérutti P., Ozil A., Loisel S., Pugnière M., Ubiali G., Zoete V., Michielin O. et al., 2016. Journal of Immunology, 196 (7) pp. 3199-3211. Peer-reviewed.
 
Enhancing actions of peptides derived from the γ-chain of fetal human hemoglobin on the immunostimulant activities of monophosphoryl lipid A.
Ulmer A.J., Kaconis Y., Heinbockel L., Correa W., Alexander C., Rietschel E.T., Mach J.P., Gorczynski R.M., Heini A., Rössle M. et al., 2016. Innate Immunity, 22 (3) pp. 168-180.
Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.
Zhang L., Tschumi B.O., Lopez-Mejia I.C., Oberle S.G., Meyer M., Samson G., Rüegg M.A., Hall M.N., Fajas L., Zehn D. et al., 2016. Cell Reports, 14 (5) pp. 1206-1217. Peer-reviewed.
Classification of current anticancer immunotherapies.
Galluzzi L., Vacchelli E., Bravo-San Pedro J.M., Buqué A., Senovilla L., Baracco E.E., Bloy N., Castoldi F., Abastado J.P., Agostinis P. et al., 2014. Oncotarget, 5 (24) pp. 12472-12508.
 
In memory of Garry Abelev 1928-2013.
Engelhardt N., Mach J.P., 2014. Tumour Biology, 35 (7) pp. 6169-6173.
iNKT/CD1d-antitumor immunotherapy significantly increases the efficacy of therapeutic CpG/peptide-based cancer vaccine.
Corgnac S., Perret R., Zhang L., Mach J.P., Romero P., Donda A., 2014. Journal for Immunotherapy of Cancer, 2 (1) p. 39. Peer-reviewed.
 
Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function.
Zhang L., Tschumi B.O., Corgnac S., Rüegg M.A., Hall M.N., Mach J.P., Romero P., Donda A., 2014. Journal of Immunology, 193 (4) pp. 1759-1765.
CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses.
Corgnac S., Perret R., Derré L., Zhang L., Stirnemann K., Zauderer M., Speiser D.E., Mach J.P., Romero P., Donda A., 2013. Cancer Immunology, Immunotherapy, 62 (4) pp. 747-760.
Improving the chance of cure of follicular lymphoma by combining immunotherapy and radioimmunotherapy based on anti-CD20 antibodies?
Buchegger F., Mach J.P., Press O.W., Bischof Delaloye A., Larson S.M., Prior J.O., Ketterer N., 2013. Annals of Oncology, 24 (7) pp. 1948-1949.
Radioimmunotherapy combined with maintenance anti-CD20 antibody may trigger long-term protective T cell immunity in follicular lymphoma patients.
Buchegger F., Larson S.M., Mach J.P., Chalandon Y., Dietrich P.Y., Cairoli A., Prior J.O., Romero P., Speiser D.E., 2013. Clinical and Developmental Immunology, 2013 p. 875343.
 
In pancreatic carcinoma, dual EGFR/HER2 targeting with cetuximab/trastuzumab is more effective than treatment with trastuzumab/erlotinib or lapatinib alone: implication of receptors' down-regulation and dimers' disruption.
Larbouret C., Gaborit N., Chardès T., Coelho M., Campigna E., Bascoul-Mollevi C., Mach J.P., Azria D., Robert B., Pèlegrin A., 2012. Neoplasia, 14 (2) pp. 121-130. Peer-reviewed.
Introduction to monoclonal antibodies.
Mach J.P., 2012. Cancer Immunity, 12 p. 11.
Antitumour effects of single or combined monoclonal antibodies directed against membrane antigens expressed by human B cells leukaemia.
Loisel S., André P.A., Golay J., Buchegger F., Kadouche J., Cérutti M., Bologna L., Kosinski M., Viertl D., Delaloye A.B. et al., 2011. Molecular Cancer, 10 p. 42.
Combined cetuximab and trastuzumab are superior to gemcitabine in the treatment of human pancreatic carcinoma xenografts.
Larbouret C., Robert B., Bascoul-Mollevi C., Penault-Llorca F., Ho-Pun-Cheung A., Morisseau S., Navarro-Teulon I., Mach J.P., Pèlegrin A., Azria D., 2010. Annals of Oncology, 21 (1) pp. 98-103. Peer-reviewed.
 
Possible misinterpretation of the mode of action of therapeutic antibodies in vitro: homotypic adhesion and flow cytometry result in artefactual direct cell death.
Golay J., Bologna L., André P.A., Buchegger F., Mach J.P., Boumsell L., Introna M., 2010. Blood, 116 (17) pp. 3372-3373.
 
An infrared reflection-absorption spectroscopic (IRRAS) study of the interaction of lipid A and lipopolysaccharide Re with endotoxin-binding proteins.
Kerth A., Garidel P., Howe J., Alexander C., Mach J.P., Waelli T., Blume A., Rietschel E.Th., Brandenburg K., 2009. Medicinal Chemistry, 5 (6) pp. 535-542.
 
Induction of tolerogenic vs immunogenic dendritic cells (DCs) in the presence of GM-CSF is regulated by the strength of signaling from monophosphoryl lipid A (MPLA) in association with glutathione and fetal hemoglobin gamma-chain.
Khatri I., Alexander C., Brandenburg K., Fournier K., Mach J.P., Rietschel E.T., Ulmer A.J., Terzioglu E., Waelli T., Gorczynski R.M., 2009. Immunology letters, 124 (1) pp. 44-49. Peer-reviewed.
 
A role for altered TLR gene expression in association with increased expression of CD200R in the induction of mucosal tissue CD4(+) Treg in aged mice following gavage with a liver extract along with intramuscular monophosphoryl lipid A (MPLA) injection.
Khatri I., Alexander C., Brandenburg K., Fournier K., Lee L., Mach J.P., Rietschel E.T., Ulmer A.J., Waelli T., Gorczynski R.M., 2008. Experimental gerontology, 43 (8) pp. 771-781. Peer-reviewed.
 
Adjuvant radioimmunotherapy trial with iodine-131-labeled anti-carcinoembryonic antigen monoclonal antibody F6 F(ab')2 after resection of liver metastases from colorectal cancer.
Ychou M., Azria D., Menkarios C., Faurous P., Quenet F., Saint-Aubert B., Rouanet P., Pèlegrin M., Bascoul-Mollevi C., Guerreau D. et al., 2008. Clinical cancer research, 14 (11) pp. 3487-3493. Peer-reviewed.
 
Hemoglobin enhances the biological activity of synthetic and natural bacterial (endotoxic) virulence factors: a general principle.
Howe J., Richter W., Hawkins L., Rössle M., Alexander C., Fournier K., Mach J.P., Waelli T., Gorczynski R.M., Ulmer A.J. et al., 2008. Medicinal chemistry, 4 (6) pp. 520-525. Peer-reviewed.
Redirecting NK cells mediated tumor cell lysis by a new recombinant bifunctional protein.
Germain C., Campigna E., Salhi I., Morisseau S., Navarro-Teulon I., Mach J.P., Pèlegrin A., Robert B., 2008. Protein engineering, design and selection, 21 (11) pp. 665-672. Peer-reviewed.
 
Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins.
Howe J., Garidel P., Roessle M., Richter W., Alexander C., Fournier K., Mach J.P., Waelli T., Gorczynski R.M., Ulmer A.J. et al., 2008. Innate immunity, 14 (1) pp. 39-49. Peer-reviewed.
 
Sustained activation and tumor targeting of NKT cells using a CD1d-anti-HER2-scFv fusion protein induce antitumor effects in mice
Stirnemann K., Romero J. F., Baldi L., Robert B., Cesson V., Besra G. S., Zauderer M., Wurm F., Corradin G., Mach J. P. et al., 2008. Journal of Clinical Investigation, 118 (3) pp. 994-1005. Peer-reviewed.
 
An alteration in the levels of populations of CD4+ Treg is in part responsible for altered cytokine production by cells of aged mice which follows injection with a fetal liver extract.
Gorczynski R.M., Alexander C., Bessler W., Brandenburg K., Fournier K., Mach J.P., Mueller S., Rietschel E.T., Ulmer A.J., Waelli T. et al., 2007. Immunology letters, 109 (2) pp. 101-112. Peer-reviewed.
 
Biophysical characterization of the interaction of endotoxins with hemoglobins.
Howe J., Hammer M., Alexander C., Rössle M., Fournier K., Mach J.P., Waelli T., Gorczynski R.M., Ulmer A.J., Zähringer U. et al., 2007. Medicinal chemistry, 3 (1) pp. 13-20. Peer-reviewed.
 
In vivo therapeutic synergism of anti-epidermal growth factor receptor and anti-HER2 monoclonal antibodies against pancreatic carcinomas.
Larbouret C., Robert B., Navarro-Teulon I., Thèzenas S., Ladjemi M.Z., Morisseau S., Campigna E., Bibeau F., Mach J.P., Pèlegrin A. et al., 2007. Clinical Cancer Research, 13 (11) pp. 3356-3362. Peer-reviewed.
 
Active antiviral T-lymphocyte response can be redirected against tumor cells by antitumor antibody x MHC/viral peptide conjugates.
Cesson V., Stirnemann K., Robert B., Luescher I., Filleron T., Corradin G., Mach J.P., Donda A., 2006. Clinical cancer research, 12 (24) pp. 7422-7430. Peer-reviewed.
Long-term complete responses after 131I-tositumomab therapy for relapsed or refractory indolent non-Hodgkin's lymphoma.
Buchegger F., Antonescu C., Delaloye A.B., Helg C., Kovacsovics T., Kosinski M., Mach J.P., Ketterer N., 2006. British journal of cancer, 94 (12) pp. 1770-1776. Peer-reviewed.
 
Peptabody-EGF: a novel apoptosis inducer targeting ErbB1 receptor overexpressing cancer cells.
Fattah O.M., Cloutier S.M., Kündig C., Felber L.M., Gygi C.M., Jichlinski P., Leisinger H.J., Gauthier E.R., Mach J.P., Deperthes D., 2006. International Journal of Cancer, 119 (10) pp. 2455-2463. Peer-reviewed.
 
Role of MIF and glutathione, in association with fetal ovine globin chain (Hbgamma) and LPS, in induction of TNFalpha from cells of young and aged mice, and PBL from healthy human populations.
Gorczynski R.M., Alexander C., Bessler W., Brandenburg K., Fournier K., Hoffmann P., Mach J.P., Mueller S., Rietschel E.T., Terzioglu E. et al., 2006. Immunology Letters, 105 (2) pp. 140-149. Peer-reviewed.
 
A fetal sheep liver extract containing immunostimulatory substances including LPS acts as leukocyte activator in cells of LPS responder and non responder mice.
Müller S., Hoffmann P., Esche U.V., Mach J.P., Gorczynski R.M., Waelli T., Alexander C., Zähringer U., Rietschel E.T., Bessler W.G. et al., 2005. International Immunopharmacology, 5 (13-14) pp. 1809-1819. Peer-reviewed.
 
Analysis of interaction of cloned human and/or sheep fetal hemoglobin gamma-chain and LPS in augmenting induction of inflammatory cytokine production in vivo and in vitro.
Gorczynski R.M., Alexander C., Bessler W., Fournier K., Hoffmann P., Mach J.P., Rietschel E.T., Song L., Waelli T., Westphal O. et al., 2005. Immunology Letters, 100 (2) pp. 120-129. Peer-reviewed.
 
MHC class I-related chain A conjugated to antitumor antibodies can sensitize tumor cells to specific lysis by natural killer cells.
Germain C., Larbouret C., Cesson V., Donda A., Held W., Mach J.P., Pèlegrin A., Robert B., 2005. Clinical Cancer Research, 11 (20) pp. 7516-7522. Peer-reviewed.
 
Characterization of an interaction between fetal hemoglobin and lipid A of LPS resulting in augmented induction of cytokine production in vivo and in vitro.
Gorczynski R.M., Alexander C., Bessler W., Fournier K., Hoffmann P., Mach J.P., Manuel J., Ramakrishna V., Rietschel E.T., Song L. et al., 2004. International Immunopharmacology, 4 (14) pp. 1859-1872. Peer-reviewed.
 
Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.
Buchegger F., Adamer F., Schaffland A.O., Kosinski M., Grannavel C., Dupertuis Y.M., de Tribolet N., Mach J.P., Delaloye A.B., 2004. International Journal of Cancer, 110 (1) pp. 145-149. Peer-reviewed.
 
In vivo targeting of an anti-tumor antibody coupled to antigenic MHC class I complexes induces specific growth inhibition and regression of established syngeneic tumor grafts.
Donda A., Cesson V., Mach J.P., Corradin G., Primus F.J., Robert B., 2003. Cancer Immunity, 3 p. 11.
 
Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology.
Cloutier S.M., Chagas J.R., Mach J.P., Gygi C.M., Leisinger H.J., Deperthes D., 2002. European journal of biochemistry / FEBS, 269 (11) pp. 2747-54. Peer-reviewed.
 
Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with radiolabeled iododeoxyuridine.
Dupertuis Y.M., Vazquez M., Mach J.P., De Tribolet N., Pichard C., Slosman D.O., Buchegger F., 2001. Cancer Research, 61 (21) pp. 7971-7977.
 
Human scFv antibody fragments specific for the epithelial tumour marker MUC-1, selected by phage display on living cells.
Wong C., Waibel R., Sheets M., Mach J.P., Finnern R., 2001. Cancer Immunology, Immunotherapy, 50 (2) pp. 93-101. Peer-reviewed.
 
Redirecting anti-viral CTL against cancer cells by surface targeting of monomeric MHC class I-viral peptide conjugated to antibody fragments.
Robert B., Guillaume P., Luescher I., Doucey M.A., Cerottini J.C., Romero P., Mach J.P., 2001. Cancer Immunity, 1 (2) pp. 1-13.
 
Selection of peptides and synthesis of pentameric peptabody molecules reacting specifically with ErbB-2 receptor.
Houimel M., Schneider P., Terskikh A., Mach J.P., 2001. International Journal of Cancer, 92 (5) pp. 748-755.
 
Antibody-conjugated MHC class I tetramers can target tumor cells for specific lysis by T lymphocytes.
Robert B., Guillaume P., Luescher I., Romero P., Mach J.P., 2000. European Journal of Immunology, 30 (11) pp. 3165-3170. Peer-reviewed.
 
Combined radioimmunotherapy and radiotherapy of liver metastases from colorectal cancer: a feasibility study.
Buchegger F., Allal A.S., Roth A., Papazyan J.P., Dupertuis Y., Mirimanoff R.O., Gillet M., Pelegrin A., Mach J.P., Slosman D.O., 2000. Anticancer Research, 20 (3B) pp. 1889-1896.
Immunociblage des tumeurs: situation et perspectives en 2000
Pèlegrin A., Xavier F., Barbet J., Bartholeyns J., Baty D., Buchegger F., Chatal J.F., Dufief F., Gurreau D., Gruaz-Guyon A. et al., 2000. Bulletin du Cancer, 87 (11) pp. 777-791. Peer-reviewed.
 
Prognostic value of postoperative carcinoembryonic antigen concentration and extent of invasion of resection margins after hepatic resection for colorectal metastases.
Gervaz P., Blanchard A., Pampallona S., Mach J.P., Fontolliet C., Gillet M., 2000. European Journal of Surgery, 166 (7) pp. 557-561. Peer-reviewed.
 
Radioimmunotherapy of colorectal cancer liver metastases: combination with radiotherapy.
Buchegger F., Roth A., Allal A., Dupertuis Y.M., Slosman D.O., Delaloye A.B., Mach J.P., 2000. Annals of the New York Academy of Sciences, 910 pp. 263-9; discussion 269-70. Peer-reviewed.
 
Streptabody, a high avidity molecule made by tetramerization of in vivo biotinylated, phage display-selected scFv fragments on streptavidin.
Cloutier S.M., Couty S., Terskikh A., Marguerat L., Crivelli V., Pugnières M., Mani J.C., Leisinger H.J., Mach J.P., Deperthes D., 2000. Molecular Immunology, 37 (17) pp. 1067-1077. Peer-reviewed.
 
Induction in transgenic mice of HLA-A2.1-restricted cytotoxic T cells specific for a peptide sequence from a mutated p21ras protein.
Escobar P., Yu Z., Terskikh A., Holmes N., Corradin G., Mach J.P., Healy F., 1999. Clinical and Experimental Immunology, 116 (2) pp. 214-219.
Involvement of circulating CEA in liver metastases from colorectal cancers re-examined in a new experimental model.
Leconte A., Garambois V., Ychou M., Robert B., Pourquier D., Terskikh A., Mach J.P., Pèlegrin A., 1999. British Journal of Cancer, 80 (9) pp. 1373-1379. Peer-reviewed.
 
New inhibitors of Helicobacter pylori urease holoenzyme selected from phage-displayed peptide libraries.
Houimel M., Mach J.P., Corthésy-Theulaz I., Corthésy B., Fisch I., 1999. European Journal of Biochemistry, 262 (3) pp. 774-780.
 
Stable one-step technetium-99m labeling of His-tagged recombinant proteins with a novel Tc(I)-carbonyl complex.
Waibel R., Alberto R., Willuda J., Finnern R., Schibli R., Stichelberger A., Egli A., Abram U., Mach J.P., Plückthun A. et al., 1999. Nature biotechnology, 17 (9) pp. 897-901. Peer-reviewed.
 
Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA).
Robert B., Dorvillius M., Buchegger F., Garambois V., Mani J.C., Pugnières M., Mach J.P., Pèlegrin A., 1999. International Journal of Cancer, 81 (2) pp. 285-291. Peer-reviewed.
 
An anti-CD19 antibody coupled to a tetanus toxin peptide induces efficient Fas ligand (FasL)-mediated cytotoxicity of a transformed human B cell line by specific CD4+ T cells.
Eberl G., Jiang S., Yu Z., Schneider P., Corradin G., Mach J.P., 1998. Clinical and Experimental Immunology, 114 (2) pp. 173-178. Peer-reviewed.
 
Long circulating half-life and high tumor selectivity of the photosensitizer meta-tetrahydroxyphenylchlorin conjugated to polyethylene glycol in nude mice grafted with a human colon carcinoma.
Westerman P., Glanzmann T., Andrejevic S., Braichotte D.R., Forrer M., Wagnieres G.A., Monnier P., van den Bergh H., Mach J.P., Folli S., 1998. International Journal of Cancer, 76 (6) pp. 842-850. Peer-reviewed.
 
Phase-I/II radio-immunotherapy study with Iodine-131-labeled anti-CEA monoclonal antibody F6 F(ab')2 in patients with non-resectable liver metastases from colorectal cancer.
Ychou M., Pelegrin A., Faurous P., Robert B., Saccavini J.C., Guerreau D., Rossi J.F., Fabbro M., Buchegger F., Mach J.P. et al., 1998. International Journal of Cancer, 75 (4) pp. 615-619.
 
"Peptabody": a new type of high avidity binding protein.
Terskikh A.V., Le Doussal J.M., Crameri R., Fisch I., Mach J.P., Kajava A.V., 1997. Proceedings of the National Academy of Sciences of the United States of America, 94 (5) pp. 1663-1668. Peer-reviewed.
 
Comparison of copper-67- and iodine-125-labeled anti-CEA monoclonal antibody biodistribution in patients with colorectal tumors.
Delaloye A.B., Delaloye B., Buchegger F., Vogel C.A., Gillet M., Mach J.P., Smith A., Schubiger P.A., 1997. Journal of Nuclear Medicine, 38 (6) pp. 847-853. Peer-reviewed.
 
Timing effects of combined radioimmunotherapy and radiotherapy on a human solid tumor in nude mice.
Sun L.Q., Vogel C.A., Mirimanoff R.O., Coucke P., Slosman D.O., Mach J.P., Buchegger F., 1997. Cancer Research, 57 (7) pp. 1312-1319. Peer-reviewed.
 
Combined effects of interleukin-3 and interleukin-11 on hematopoiesis in irradiated mice
Galmiche M.C., Vogel C.A., Bischof Delaloye A., Schmidt P.M., Healy F., Mach J.P., Buchegger F., 1996/09. Experimental Hematology, 24 (11) pp. 1298-306.
 
Biodistribution of anti-CEA F(ab')2 fragments after intra-arterial and intravenous injection in patients with liver metastases due to colorectal carcinoma.
Buchegger F., Gillet M., Doenz F., Vogel C.A., Achtari C., Mach J.P., Delaloye B., Delaloye A.B., 1996. Nuclear Medicine Communications, 17 (6) pp. 500-503. Peer-reviewed.
 
Carcinoembryonic antigen expression, antibody localisation and immunophotodetection of human colon cancer liver metastases in nude mice: a model for radioimmunotherapy.
Vogel C.A., Galmiche M.C., Westermann P., Sun L.Q., Pèlegrin A., Folli S., Bischof Delaloye A., Slosman D.O., Mach J.P., Buchegger F., 1996. International Journal of Cancer, 67 (2) pp. 294-302.
 
Cytokine targeting in tumors using a bispecific antibody directed against carcinoembryonic antigen and tumor necrosis factor alpha.
Robert B., Mach J.P., Mani J.C., Ychou M., Folli S., Artus J.C., Pèlegrin A., 1996. Cancer research, 56 (20) pp. 4758-4765. Peer-reviewed.
 
Higher efficiency of 131I-labeled anti-carcinoembryonic antigen-monoclonal antibody F(ab')2 as compared to intact antibodies in radioimmunotherapy of established human colon carcinoma grafted in nude mice.
Buchegger F., Mach J.P., Folli S., Delaloye B., Bischof-Delaloye A., Pèlegrin A., 1996. Recent Results in Cancer Research, 141 pp. 19-35.
 
Potential value of biliary CEA assay in early detection of colorectal adenocarcinoma liver metastases.
Frikart L., Fournier K., Mach J.P., Givel J.C., 1995. European Journal of Surgical Oncology, 21 (3) pp. 276-279. Peer-reviewed.
 
Radiolabeled chimeric anti-CEA monoclonal antibody compared with the original mouse monoclonal antibody for surgically treated colorectal carcinoma.
Buchegger F., Mach J.P., Pèlegrin A., Gillet M., Vogel C.A., Buclin T., Ryser J.E., Delaloye B., Delaloye A.B., 1995. Journal of Nuclear Medicine, 36 (3) pp. 420-429.
 
Anti-idiotypic monoclonal antibody AB3, reacting with the primary antigen (CEA), can localize in human colon-carcinoma xenografts as efficiently as AB1.
de Moraes J.Z., Gesztesi J.L., Westermann P., Le Doussal J.M., Lopes J.D., Mach J.P., 1994. International Journal of Cancer, 57 (4) pp. 586-591. Peer-reviewed.
 
Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice.
Folli S., Westermann P., Braichotte D., Pèlegrin A., Wagnières G., van den Bergh H., Mach J.P., 1994. Cancer Research, 54 (10) pp. 2643-2649. Peer-reviewed.
 
Covalent binding of C3b to monoclonal antibodies selectively up-regulates heavy chain epitope recognition by T cells.
Santoro L., Drouet C., Reboul A., Mach J.P., Colomb M.G., 1994. European Journal of Immunology, 24 (7) pp. 1620-1626. Peer-reviewed.
 
Dimeric recombinant IgA directed against carcino-embryonic antigen, a novel tool for carcinoma localization.
Terskikh A., Couty S., Pèlegrin A., Hardman N., Hunziker W., Mach J.P., 1994. Molecular immunology, 31 (17) pp. 1313-1319. Peer-reviewed.
 
Peptide-antibody conjugates for tumour therapy: a MHC-class-II-restricted tetanus toxin peptide coupled to an anti-Ig light chain antibody can induce cytotoxic lysis of a human B-cell lymphoma by specific CD4 T cells.
Yu Z., Healy F., Valmori D., Escobar P., Corradin G., Mach J.P., 1994. International Journal of Cancer, 56 (2) pp. 244-248.
Direct comparison of a radioiodinated intact chimeric anti-CEA MAb with its F(ab')2 fragment in nude mice bearing different human colon cancer xenografts.
Vogel C.A., Bischof-Delaloye A., Mach J.P., Pèlegrin A., Hardman N., Delaloye B., Buchegger F., 1993. British Journal of Cancer, 68 (4) pp. 684-690. Peer-reviewed.
 
Marked increase in the secretion of a fully antigenic recombinant carcinoembryonic antigen obtained by deletion of its hydrophobic tail.
Terskikh A., Mach J.P., Pèlegrin A., 1993. Molecular Immunology, 30 (10) pp. 921-927. Peer-reviewed.
 
Potential contribution of 131I-labelled monoclonal anti-CEA antibodies in the treatment of liver metastases from colorectal carcinomas: pretherapeutic study with dose recovery in resected tissues.
Ychou M., Ricard M., Lumbroso J., Rougier P., Mach J.P., Buchegger F., Saccavini J.C., Lasser P., Elias D., Eschwege F., 1993. European Journal of Cancer, 29A (8) pp. 1105-1111. Peer-reviewed.
 
Site-specific conjugation of a radioiodinated phenethylamine derivative to a monoclonal antibody results in increased radioactivity localization in tumor.
Kurth M., Pèlegrin A., Rose K., Offord R.E., Pochon S., Mach J.P., Buchegger F., 1993. Journal of Medicinal Chemistry, 36 (9) pp. 1255-1261. Peer-reviewed.
 
Tumor-necrosis factor can enhance radio-antibody uptake in human colon carcinoma xenografts by increasing vascular permeability.
Folli S., Pèlegrin A., Chalandon Y., Yao X., Buchegger F., Lienard D., Lejeune F., Mach J.P., 1993. International Journal of Cancer, 53 (5) pp. 829-836. Peer-reviewed.
 
Combined radioimmunotherapy and chemotherapy of human colon carcinoma grafted in nude mice, advantages and limitations.
Chalandon Y., Mach J.P., Pèlegrin A., Folli S., Buchegger F., 1992. Anticancer Research, 12 (4) pp. 1131-1139. Peer-reviewed.
 
Different behaviour of mouse-human chimeric antibody F(ab')2 fragments of IgG1, IgG2 and IgG4 sub-class in vivo.
Buchegger F., Pèlegrin A., Hardman N., Heusser C., Lukas J., Dolci W., Mach J.P., 1992. International Journal of Cancer, 50 (3) pp. 416-422.
 
Induction of an immune response through the idiotypic network with monoclonal anti-idiotype antibodies in the carcinoembryonic antigen system.
de Moraes J.Z., Carneiro C.R., Buchegger F., Mach J.P., Lopes J.D., 1992. Journal of Cellular Biochemistry, 50 (3) pp. 324-335. Peer-reviewed.
 
Les anticorps monoclonaux radiomarqués en tant que missiles anti-tumeurs, leurs succès diagnostiques, leur potentiel thérapeutique
Mach J.P., Pèlegrin A., Folli S., Buchegger F., 1992. Bulletin de l'Académie Nationale de Médecine, 176 (6) pp. 879-889. Peer-reviewed.
 
Specificity and affinity of monoclonal antibodies against carcinoembryonic antigen.
Nap M., Hammarström M.L., Börmer O., Hammarström S., Wagener C., Handt S., Schreyer M., Mach J.P., Buchegger F., von Kleist S., 1992. Cancer Research, 52 (8) pp. 2329-2339.
 
Antibody-fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice.
Pèlegrin A., Folli S., Buchegger F., Mach J.P., Wagnières G., van den Bergh H., 1991. Cancer, 67 (10) pp. 2529-2537. Peer-reviewed.
 
Bone marrow dosimetry in rats using direct tissue counting after injection of radio-iodinated intact monoclonal antibodies or F(ab')2 fragments.
Buchegger F., Chalandon Y., Pèlegrin A., Hardman N., Mach J.P., 1991. Journal of Nuclear Medicine, 32 (7) pp. 1414-1421. Peer-reviewed.
 
Characterization and detection of naturally occurring antibodies against IL-1 alpha and IL-1 beta in normal human plasma.
Gallay P., Mach J.P., Carrel S., 1991. European Cytokine Network, 2 (5) pp. 329-338. Peer-reviewed.
 
Cloning of an interferon-gamma regulated human melanoma-associated antigen: identity to the intercellular adhesion molecule ICAM-1.
Hayoz D., Rimoldi D., Kühn L., Mach J.P., Carrel S., 1991. Melanoma Research, 1 (4) pp. 251-259. Peer-reviewed.
 
Detachment of cell surface-bound anticarcinoembryonic antigen immune complexes by phospholipase C.
Matzku S., Mach J.P., Buchegger F., Moldenhauer G., Stadler M., Kalthoff H., 1991. Tumour Biology, 12 (5) pp. 272-278. Peer-reviewed.
 
Imaging and therapy with monoclonal antibodies in non-hematopoietic tumors.
Mach J.P., Pèlegrin A., Buchegger F., 1991. Current Opinion in Immunology, 3 (5) pp. 685-693. Peer-reviewed.
 
Radioimmuno positron emission tomography with monoclonal antibodies: a new approach to quantifying in vivo tumour concentration and biodistribution for radioimmunotherapy.
Westera G., Reist H.W., Buchegger F., Heusser C.H., Hardman N., Pfeiffer A., Sharma H.L., von Schulthess G.K., Mach J.P., 1991. Nuclear Medicine Communications, 12 (5) pp. 429-437. Peer-reviewed.
Elevated CA125 levels in patients with metastatic breast carcinoma.
Perey L., Hayes D.F., Tondini C., van Melle G., Bauer J., Lemarchand T., Reymond M., Mach J.P., Leyvraz S., 1990. British Journal of Cancer, 62 (4) pp. 668-670. Peer-reviewed.
 
Iodine-131-labeled MAb F(ab')2 fragments are more efficient and less toxic than intact anti-CEA antibodies in radioimmunotherapy of large human colon carcinoma grafted in nude mice.
Buchegger F., Pèlegrin A., Delaloye B., Bischof-Delaloye A., Mach J.P., 1990. Journal of Nuclear Medicine, 31 (6) pp. 1035-1044. Peer-reviewed.
 
Radioimmunotherapy of colon carcinoma with I-131 labeled antibodies, successful experimental results and clinical dosimetry study.
Mach J.P., Buchegger F., Pelegrin A., Ychou M., Ricard M., Lumbroso J., Rougier P., Lasser P., Elias D., Saccavini J.C., 1990. Pathologie-Biologie, 38 (8) p. 819. Peer-reviewed.
 
A novel derivative of the chelon desferrioxamine for site-specific conjugation to antibodies.
Pochon S., Buchegger F., Pélegrin A., Mach J.P., Offord R.E., Ryser J.E., Rose K., 1989. International Journal of Cancer, 43 (6) pp. 1188-1194. Peer-reviewed.
 
A novel interferon-gamma regulated human melanoma-associated antigen, gp33-38, defined by monoclonal antibody Me14-D12. II. Molecular cloning of a genomic probe.
Audette M., Carrel S., Hayoz D., Giuffrè L., Mach J.P., Kühn L.C., 1989. Molecular Immunology, 26 (6) pp. 515-522. Peer-reviewed.
Ablation of human colon carcinoma in nude mice by 131I-labeled monoclonal anti-carcinoembryonic antigen antibody F(ab')2 fragments.
Buchegger F., Pfister C., Fournier K., Prevel F., Schreyer M., Carrel S., Mach J.P., 1989. Journal of Clinical Investigation, 83 (5) pp. 1449-1456. Peer-reviewed.
 
Antigenic sites in carcinoembryonic antigen.
Hammarstrom S., Shively J.E., Paxton R.J., Beatty B.G., Larsson A., Ghosh R., Bormer O., Buchegger F., Mach J.P., Burtin P., 1989. Cancer Research, 49 (17) pp. 4852-4858. Peer-reviewed.
 
Clinical value of immunoscintigraphy in colorectal carcinoma patients: a prospective study.
Bischof-Delaloye A., Delaloye B., Buchegger F., Gilgien W., Studer A., Curchod S., Givel J.C., Mosimann F., Pettavel J., Mach J.P., 1989. Journal of Nuclear Medicine, 30 (10) pp. 1646-1656. Peer-reviewed.
 
Generation of a recombinant mouse-human chimaeric monoclonal antibody directed against human carcinoembryonic antigen.
Hardman N., Gill L.L., De Winter R.F., Wagner K., Hollis M., Businger F., Ammaturo D., Buchegger F., Mach J.P., Heusser C., 1989. International Journal of Cancer, 44 (3) pp. 424-433. Peer-reviewed.
 
In vivo localization of a bispecific antibody which targets human T lymphocytes to lyse human colon cancer cells.
Barr I.G., Miescher S., von Fliedner V., Buchegger F., Barras C., Lanzavecchia A., Mach J.P., Carrel S., 1989. International Journal of Cancer, 43 (3) pp. 501-507. Peer-reviewed.
 
A novel IFN-gamma regulated human melanoma associated antigen gp33-38 defined by monoclonal antibody Me14/D12. I. Identification and immunochemical characterization.
Giuffré L., Isler P., Mach J.P., Carrel S., 1988. Journal of immunology, 141 (6) pp. 2072-2078. Peer-reviewed.
 
Arbeitsgruppe "Tumorimmunologie": Tumorimmunologie des Gastrointestinaltraktes--Experimentelle und klinische Erfahrungen [The Tumor Immunology Study Group: tumor immunology of the gastrointestinal tract--experimental and clinical experiences]
Knuth A., Kalthoff H., Wagener C., Zimmermann W., Kern H., Mach J.P., Douillard J.Y., Büchler M., 1988. Zeitschrift für Gastroenterologie. Verhandlungsband, 23 pp. 238-251.
 
Cyclic AMP induces differentiation in vitro of human melanoma cells.
Giuffrè L., Schreyer M., Mach J.P., Carrel S., 1988. Cancer, 61 (6) pp. 1132-1141. Peer-reviewed.
 
Imaging of human leukemic T-cell xenografts in nude mice by radiolabeled monoclonal antibodies and F(ab')2 fragments.
Vacca A., Buchegger F., Carrel S., Mach J.P., 1988. Cancer, 61 (1) pp. 58-67. Peer-reviewed.
 
Immunoscintigraphic localization of inflammatory lesions: concept, radiolabelling and in vitro testing of a granulocyte specific antibody.
Andres R.Y., Schubiger P.A., Tiefenauer L., Seybold K., Locher J.T., Mach J.P., Buchegger F., 1988. European Journal of Nuclear Medicine, 13 (11) pp. 582-586. Peer-reviewed.
 
In vivo localisation of radiolabelled monoclonal antibody in human gliomas.
Behnke J., Mach J.P., Buchegger F., Carrel S., Delaloye B., De Tribolet N., 1988. British Journal of Neurosurgery, 2 (2) pp. 193-197. Peer-reviewed.
 
Monoclonal antibodies: their application in the diagnosis and management of CNS tumors.
de Tribolet N., Frank E., Mach J.P., 1988. Clinical Neurosurgery, 34 pp. 446-456.
 
Radioimmunotherapy of human colon carcinoma by 131I-labelled monoclonal anti-CEA antibodies in a nude mouse model.
Buchegger F., Vacca A., Carrel S., Schreyer M., Mach J.P., 1988. International Journal of Cancer, 41 (1) pp. 127-134. Peer-reviewed.
 
Comparative localization of glioma-reactive monoclonal antibodies in vivo in an athymic mouse human glioma xenograft model.
Wikstrand C.J., McLendon R.E., Carrel S., Kemshead J.T., Mach J.P., Coakham H.B., de Tribolet N., Bullard D.E., Zalutsky M.R., Bigner D.D., 1987. Journal of Neuroimmunology, 15 (1) pp. 37-56.
 
Cultured human fetal astrocytes can be induced by interferon-gamma to express HLA-DR.
Pulver M., Carrel S., Mach J.P., de Tribolet N., 1987. Journal of neuroimmunology, 14 (2) pp. 123-133. Peer-reviewed.
 
Identification of a novel 45-kDa cell surface molecule involved in activation of the human Jurkat T cell line.
Carrel S., Isler P., Salvi S., Giuffrè L., Pantaleo G., Mach J.P., Cerottini J.C., 1987. European Journal of Immunology, 17 (10) pp. 1395-1402. Peer-reviewed.
 
L'immunoscintigraphie par les anticorps monoclonaux radiomarqués. Evolution d'une méthode de diagnostic du cancer et espoir d'une nouvelle forme de thérapie [Immunoscintigraphy using radio-labeled monoclonal antibodies. Development of a method of cancer diagnosis and hopes for a new form of therapy].
Mach J.P., Bischof-Delaloye A., Curchod S., Studer A., Grob J.P., Volant J.C., Mosimann F., Givel J.C., Douglas P., Leyvraz S., 1987. Schweizerische Medizinische Wochenschrift, 117 (29) pp. 1076-1086. Peer-reviewed.
 
Monoclonal antibody against carcinoembryonic antigen (CEA) identifies two new forms of crossreacting antigens of molecular weight 90,000 and 160,000 in normal granulocytes.
Audette M., Buchegger F., Schreyer M., Mach J.P., 1987. Molecular Immunology, 24 (11) pp. 1177-1186. Peer-reviewed.
 
Penetration and binding of radiolabeled anti-carcinoembryonic antigen monoclonal antibodies and their antigen binding fragments in human colon multicellular tumor spheroids.
Sutherland R., Buchegger F., Schreyer M., Vacca A., Mach J.P., 1987. Cancer Research, 47 (6) pp. 1627-1633. Peer-reviewed.
 
Phorbol 12-myristate 13-acetate induces surface expression of T3 on human immature T cell lines with and without concomitant expression of the T cell antigen receptor complex.
Carrel S., Mach J.P., Miescher G., Salvi S., Giuffrè L., Schreyer M., Isler P., 1987. European Journal of Immunology, 17 (8) pp. 1079-1087. Peer-reviewed.
 
Swine monoclonal antibodies of high affinity and specificity to carcinoembryonic antigen.
Buchegger F., Fournier K., Schreyer M., Carrel S., Mach J.P., 1987. Journal of the National Cancer Institute, 79 (2) pp. 337-342. Peer-reviewed.
 
Cancer detection by immunoscintigraphy, selection, and clinical application of monoclonal anti-CEA antibodies and their F(ab')2 or Fab fragments.
Grob J.P., Mach J.P., Buchegger F., Schreyer M., Mosimann F., Besson A., Pettavel J., von Fliedner V., Bischof-Delaloye A., Delaloye B., 1986. Recent Results in Cancer Research, 100 pp. 73-79.
 
Characterization of membrane vesicles circulating in the serum of patients with common acute lymphoblastic leukemia.
Losa G.A., Heumann D., Carrel S., von Fliedner V., Mach J.P., 1986. Laboratory investigation, 55 (5) pp. 573-579. Peer-reviewed.
Detection of colorectal carcinoma by emission-computerized tomography after injection of 123I-labeled Fab or F(ab')2 fragments from monoclonal anti-carcinoembryonic antigen antibodies.
Delaloye B., Bischof-Delaloye A., Buchegger F., von Fliedner V., Grob J.P., Volant J.C., Pettavel J., Mach J.P., 1986. Journal of Clinical Investigation, 77 (1) pp. 301-311. Peer-reviewed.
 
Expression on human thymocytes of the idiotypic structures (Ti) from two leukemia T cell lines Jurkat and HPB-ALL.
Carrel S., Isler P., Schreyer M., Vacca A., Salvi S., Giuffre L., Mach J.P., 1986. European journal of immunology, 16 (6) pp. 649-652. Peer-reviewed.
 
Heterogeneity of the induction of HLA-DR expression by human immune interferon on glioma cell lines and their clones.
Piguet V., Carrel S., Diserens A.C., Mach J.P., de Tribolet N., 1986. Journal of the National Cancer Institute, 76 (2) pp. 223-228. Peer-reviewed.
 
Imaging of inflammatory and infectious lesions after injection of radioiodinated monoclonal anti-granulocytes antibodies.
Locher J.T., Seybold K., Andres R.Y., Schubiger P.A., Mach J.P., Buchegger F., 1986. Nuclear Medicine Communications, 7 (9) pp. 659-670. Peer-reviewed.
 
Immunochemical characterization of two antigens recognized by new monoclonal antibodies against human colon carcinoma.
Girardet C., Vacca A., Schmidt-Kessen A., Schreyer M., Carrel S., Mach J.P., 1986. Journal of immunology, 136 (4) pp. 1497-1503. Peer-reviewed.
 
In vitro and in vivo tumor models for studies of distribution of radiolabelled monoclonal antibodies and fragments.
Buchegger F., Halpern S.E., Sutherland R.M., Schreyer M., Mach J.P., 1986. Nuklearmedizin. Nuclear Medicine, 25 (6) pp. 207-209. Peer-reviewed.
 
Monoclonal antibodies against idiotypic determinant(s) of the T cell receptor from HPB-ALL cells induce IL2 production in Jurkat cells without apparent evidence of binding.
Carrel S., Giuffrè L., Vacca A., Salvi S., Mach J.P., Isler P., 1986. European journal of immunology, 16 (7) pp. 823-828. Peer-reviewed.
 
Selective tumor localization of radiolabeled anti-human melanoma monoclonal antibody fragment demonstrated in the nude mouse model.
Buchegger F., Mach J.P., Leonnard P., Carrel S., 1986. Cancer, 58 (3) pp. 655-662. Peer-reviewed.
 
Caractéristiques cliniques des leucémies lymphoblastiques aiguës de type T immature (E-rosette négatif) détecté par l'anticorps monoclonal LAU-A1 [Clinical characteristics of immature T-type (negative E-rosette) acute lymphoblastic leukemia detected by LAU-A1 monoclonal antibody]
von Fliedner V., Grob J.P., Heumann D., Carrel S., Chapuis B., Fopp M., Imbach P., Cavalli F., Mach J.P., 1985. Schweizerische medizinische Wochenschrift, 115 (43) pp. 1515-1516. Peer-reviewed.
 
Heterogeneity of Ia antigen expression on myeloblastic leukaemias: correlation with stage of maturation defined by cytochemical markers.
Heumann D., Carrel S., Morell A., Gratwohl A., Fopp M., Schneider P., Barras C., Mach J.P., von Fliedner V.E., 1985. British journal of haematology, 59 (4) pp. 681-687. Peer-reviewed.
 
Phenotyping of 60 cultured human gliomas and 34 other neuroectodermal tumors by means of monoclonal antibodies against glioma, melanoma and HLA-DR antigens.
de Muralt B., de Tribolet N., Diserens A.C., Stavrou D., Mach J.P., Carrel S., 1985. European journal of cancer and clinical oncology, 21 (2) pp. 207-216. Peer-reviewed.
 
Radiolabeling of monoclonal antibody against carcinoembryonic antigen with 88Y and biodistribution studies.
Buchsbaum D.J., Hanna D.E., Randall B.C., Buchegger F., Mach J.P., 1985. International Journal of Nuclear Medicine and Biology, 12 (2) pp. 79-82.
 
The human Ia-associated invariant chain is synthesized in Ia-negative B cell variants and is not expressed on the cell surface of both Ia-negative and Ia-positive parental cells.
Accolla R.S., Carra G., Buchegger F., Carrel S., Mach J.P., 1985. Journal of Immunology, 134 (5) pp. 3265-3271. Peer-reviewed.
 
The immunobiology of human gliomas.
Piguet V., Diserens A.C., Carrel S., Mach J.P., de Tribolet N., 1985. Springer seminars in immunopathology, 8 (1-2) pp. 111-127. Peer-reviewed.
 
Antigenic heterogeneity of clones and subclones from human melanoma cell lines demonstrated by a panel of monoclonal antibodies and flow microfluorometry analysis.
Cillo C., Mach J.P., Schreyer M., Carrel S., 1984. International Journal of Cancer, 34 (1) pp. 11-20. Peer-reviewed.
 
Brain tumor-associated antigens.
de Tribolet N., Carrel S., Mach J.P., 1984. Progress in Experimental Tumor Research, 27 pp. 118-131. Peer-reviewed.
Demonstration of HLA-DR antigens in normal human brain.
De Tribolet N., Hamou M.F., Mach J.P., Carrel S., Schreyer M., 1984. Journal of neurology, neurosurgery, and psychiatry, 47 (4) pp. 417-418. Peer-reviewed.
Detection of the common acute lymphoblastic leukemia antigen in the serum of leukemia patients.
Carrel S., Buchegger F., Heumann D., Girardet C., Barras C., Losa G., Mach J.P., von Fliedner V., 1984. Journal of Clinical Investigation, 74 (5) pp. 1882-1885. Peer-reviewed.
 
Immunoscintigraphie avec tomographie d'émission dans les cancers de la thyroïde
Parmentier C., Lumbroso J., Schlumberger M., Gardet P., Mach J.P., Berche C., Rougier P., Caillou B., Tubiana M., 1984. Annales de Médecine Interne, 135 (5) pp. 345-350.
 
Monoclonal antibodies identify a CEA crossreacting antigen of 95 kD (NCA-95) distinct in antigenicity and tissue distribution from the previously described NCA of 55 kD.
Buchegger F., Schreyer M., Carrel S., Mach J.P., 1984. International Journal of Cancer, 33 (5) pp. 643-649. Peer-reviewed.
 
Monoclonal antibody against a "Pan-T-cell" antigen expressed by thymocytes, peripheral T-lymphocytes and T-cell leukemias.
Carrel S., Gross N., Heumann D., Sekaly R.P., Girardet C., Schmidt-Kessen A., Mach J.P., 1984. Molecular Immunology, 21 (10) pp. 831-840. Peer-reviewed.
 
Expression of common acute lymphoblastic leukemia antigen (CALLA) on human malignant melanoma cell lines.
Carrel S., Schmidt-Kessen A., Mach J.P., Heumann D., Girardet C., 1983. Journal of Immunology, 130 (5) pp. 2456-2460.
 
Human large granular lymphocytes contain an esterase activity usually considered as specific for the myeloid series.
Heumann D., Colombatti M., Mach J.P., 1983. European Journal of Immunology, 13 (3) pp. 254-258.
 
Identification by a monoclonal antibody of a glycolipid highly expressed by cells from the human myeloid lineage.
Girardet C., Ladisch S., Heumann D., Mach J.P., Carrel S., 1983. International Journal of Cancer, 32 (2) pp. 177-183.
 
Immunoscintigraphy for the detection of human carcinoma after injection of radiolabeled monoclonal anti-carcinoembryonic antigen antibodies.
Mach J.P., Buchegger F., Forni M., Ritschard J., Carrel S., Egley R., Donath A., Rohner A., 1983. Current Topics in Microbiology and Immunology, 104 pp. 49-55.
 
Monoclonal antibodies to carcinoembryonic antigen: ionic strength as a factor in the selection of antibodies for immunoscintigraphy.
Haskell C.M., Buchegger F., Schreyer M., Carrel S., Mach J.P., 1983. Cancer Research, 43 (8) pp. 3857-3864.
Radiolabeled fragments of monoclonal antibodies against carcinoembryonic antigen for localization of human colon carcinoma grafted into nude mice.
Buchegger F., Haskell C.M., Schreyer M., Scazziga B.R., Randin S., Carrel S., Mach J.P., 1983. Journal of Experimental Medicine, 158 (2) pp. 413-427.
 
Reactivity of antiglioma monoclonal antibodies for a large panel of cultured gliomas and other neuroectoderm derived tumors.
de Muralt B., de Tribolet N., Diserens A.C., Carrel S., Mach J.P., 1983. Anticancer Research, 3 (1) pp. 1-6.
 
Tumor localization in patients by radiolabeled monoclonal antibodies against colon carcinoma.
Mach J.P., Chatal J.F., Lumbroso J.D., Buchegger F., Forni M., Ritschard J., Berche C., Douillard J.Y., Carrel S., Herlyn M. et al., 1983. Cancer Research, 43 (11) pp. 5593-5600.
 
Utilisation en tomoscintigraphie d'anticorps monoclonaux radio-marqués pour la détection chez l'homme des cancers digestifs et des cancers médullaires de la thyroïde
Lumbroso J., Berche C., Mach J.P., Rougier P., Aubry F., Buchegger F., Lasser P., Parmentier C., Tubiana M., 1983. Bulletin du Cancer, 70 (2) pp. 96-102. Peer-reviewed.
 
Expression of neuroectodermal antigens common to melanomas, gliomas, and neuroblastomas. I. Identification by monoclonal anti-melanoma and anti-glioma antibodies.
Carrel S., de Tribolet N., Mach J.P., 1982. Acta Neuropathologica, 57 (2-3) pp. 158-164.
 
Human melanoma-associated and glioma-associated antegen(S) identified by monoclonal-antibodies
Carrel S., Detribolet N., Mach J.P., 1982. Methods in Cancer Research, 20 pp. 317-354.
 
Monoclonal antibodies against carcinoembryonic antigen (CEA) used in a solid-phase enzyme immunoassay. First clinical results.
Buchegger F., Phan M., Rivier D., Carrel S., Accolla R.S., Mach J.P., 1982. Journal of Immunological Methods, 49 (2) pp. 129-139.
 
Reactivity spectrum of 30 monoclonal antimelanoma antibodies to a panel of 28 melanoma and control cell lines.
Carrel S., Schreyer M., Schmidt-Kessen A., Mach J.P., 1982. Hybridoma, 1 (4) pp. 387-397.
 
Sandwich enzyme immunoassay using three monoclonal antibodies against different epitopes of carcinoembryonic antigen (CEA).
Buchegger F., Mettraux C., Accolla R.S., Carrel S., Mach J.P., 1982. Immunology Letters, 5 (2) pp. 85-91.
 
Tomoscintigraphy for detecting gastrointestinal and medullary thyroid cancers: first clinical results using radiolabelled monoclonal antibodies against carcinoembryonic antigen.
Berche C., Mach J.P., Lumbroso J.D., Langlais C., Aubry F., Buchegger F., Carrel S., Rougier P., Parmentier C., Tubiana M., 1982. British Medical Journal, 285 (6353) pp. 1447-1451.
 
Translation and assembly of HLA-DR antigens in Xenopus oocytes injected with mRNA from a human B-cell line.
Long E.O., Gross N., Wake C.T., Mach J.P., Carrel S., Accolla R., Mach B., 1982. EMBO Journal, 1 (5) pp. 649-654. Peer-reviewed.
 
Antigène carcino-embryonnaire circulant, fortement élevé et persistant, sans cancer décelable
Bonard E.C., Mach J.P., 1981. Schweizerische Medizinische Wochenschrift, 111 (48) pp. 1845-1849.
 
Classification des leucémies aiguës par les marqueurs de surface et corrélation avec le diagnostic morphologique résultats sur 111 cas
von Fliedner V., Carrel S., Morell A., Heumann D., Losa G., Hirt A., Jeannet M., Mach J.P., Cruchaud A., 1981. Schweizerische Medizinische Wochenschrift, 111 (41) pp. 1524-1526.
 
Flow cytofluorometric analysis of the binding of Vicia villosa lectin to T lymphoblasts: lack of correlation with cytolytic function.
MacDonald H.R., Mach J.P., Schreyer M., Zaech P., Cerottini J.C., 1981. Journal of Immunology, 126 (3) pp. 883-886.
 
Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photoscanning and tomoscintigraphy
Mach J.P., Buchegger F., Forni M., Ritschard J., Berche C., Lumbroso J.D., Schreyer M., Girardet C., Accolla R.S., Carrel S., 1981. Immunology Today, 2 (12) pp. 239-249.
 
Common human melanoma-associated antigen(s) detected by monoclonal antibodies.
Carrel S., Accolla R.S., Carmagnola A.L., Mach J.P., 1980. Cancer Research, 40 (7) pp. 2523-2528.
 
Detection of new cross-reacting carcinoembryonic antigen(s) on cultured tumor cells by mixed hemadsorption assay.
Dent P.B., Carrel S., Mach J.P., 1980. Journal of the National Cancer Institute, 64 (2) pp. 309-316.
 
Established murine cytolytic T-cell lines as tools for a somatic cell genetic analysis of T-cell functions.
Nabholz M., Conzelmann A., Acuto O., North M., Haas W., Pohlit H., von Boehmer H., Hengartner H., Mach J.P., Engers H. et al., 1980. Immunological Reviews, 51 pp. 125-156.
 
Monoclonal antibodies specific for carcinoembryonic antigen and produced by two hybrid cell lines.
Accolla R.S., Carrel S., Mach J.P., 1980. Proceedings of the National Academy of Sciences of the United States of America, 77 (1) pp. 563-566.
 
Presence of T 145 on cytolytic T cell lines and their lectin-resistant mutants.
Conzelmann A., Pink R., Acuto O., Mach J.P., Dolivo S., Nabholz M., 1980. European Journal of Immunology, 10 (11) pp. 860-868.
 
Tumor localization of radiolabeled antibodies against carcinoembryonic antigen in patients with carcinoma: a critical evaluation.
Mach J.P., Carrel S., Forni M., Ritschard J., Donath A., Alberto P., 1980. New England Journal of Medicine, 303 (1) pp. 5-10.
 
Use of limitations of radiolabeled anti-CEA antibodies and their fragments for photoscanning detection of human colorectal carcinomas.
Mach J.P., Forni M., Ritschard J., Buchegger F., Carrel S., Widgren S., Donath A., Alberto P., 1980. Oncodevelopmental Biology and Medicine, 1 (1) pp. 49-69.
 
Variation en sens inverse des teneurs en antigène carcino-embryonnaire et en bicarbonates dans le suc duodénal de l'homme
Capitaine Y., Voirol M., Lapp R., Mach J.P., Loizeau E., 1980. Gastroentérologie Clinique et Biologique, 4 (3) pp. 200-205.
 
Expression of "Ia-like" antigens on cells from a human endometrial carcinoma cell line, END-1.
Carrel S., Gross N., Heumann D., Mach J.P., 1979. Transplantation, 27 (6) pp. 431-433. Peer-reviewed.
 
Intérêt et limites du dosage radio-immunologique de l'antigène carcino-embryonnaire (CEA) dans l'établissement du pronostic et du traitement postopératoire des malades atteints de carcinome du gros intestin
Mach J.P., Jaeger P., Vienny H., Meyer A., Pettavel J., 1979. Schweizerische Rundschau für Medizin Praxis, 68 (26) pp. 856-863.
 
Reactivity of anti-Daudi serum with acute and chronic leukemias.
Carrel S., Gross N., Mach J.P., 1979. Cancer Research, 39 (12) pp. 5171-5176. Peer-reviewed.
 
Aspects immunologiques du cancer bronchique
Cerottini J.C., Chapuis B., Mach J.P., Louis J., 1978. Therapeutische Umschau, 35 (12) pp. 988-992.
 
Des antisérums dirigés contre l'antigène carcino-embryonnaire (CEA) peuvent induire une lyse spécifique des cellules de carcinome du côlon par des lymphocytes normaux
Carrel S.t., Delisle M.C., Mach J.P., 1978. Schweizerische Medizinische Wochenschrift, 108 (25) pp. 954-958.
 
Immunologische Methoden in der Tumordiagnostik [Immunological methods in tumor diagnosis].
Jaquet H., Mach J.P., Pettavel J., 1978. Verhandlungen der Deutschen Gesellschaft für Innere Medizin 84 pp. 567-572.
 
Long-term follow-up of colorectal carcinoma patients by repeated CEA radioimmunoassay.
Mach J.P., Vienny H., Jaeger P., Haldemann B., Egely R., Pettavel J., 1978. Cancer, 42 (3 Suppl) pp. 1439-1447.
 
Antibody-dependent cell-mediated cytolysis of human colon carcinoma cells induced by specific antisera against carcinoembryonic antigen.
Carrel S., Delisle M.C., Mach J.P., 1977. Cancer Research, 37 (8 Pt 1) pp. 2644-2650.
 
Isolation and characterization of carcinoembryonic antigen (CEA) extracted from normal human colon mucosa.
Fritsche R., Mach J.P., 1977. Immunochemistry, 14 (2) pp. 119-127.
 
Klinisch-immunologische Teste--Standortbestimmung 1976
Grob P.J., Barandun S., Carmann H., Cruchaud A., De Haller R., De Weck A., Fontana A., Frei P.C., Girard J.P., Hess M. et al., 1977. Schweizerische Medizinische Wochenschrift, 107 (11 Suppl) pp. 1995-1204.
 
Search for biological markers in breast cancer.
Mach J.P., Fritsche R., Phan M., Ozzello L., Stjernsward J., 1977. Progress in Clinical and Biological Research, 12 pp. 91-108.
 
Der Radioimmunoassay zur Ermittlung des carcinoembryonalen Antigens (CEA), seine Bedeutung und Limitierung während der postoperativen Kontrollperiode von Patienten mit colorectalem Carcino
Jaquet H., Mach J.P., Pettavel J., 1976. Langenbecks Archiv für Chirurgie, 342 pp. 243-249.
Utilité et limites du dosage de l'antigène carcinoembryonnaire (CEA) dans la surveillance postopératoire de malades atteints de carcinomes du côlon et du rectum
Mach J.P., Bertholet M.M., Jaeger P., Pettavel J., Wuilleret B., 1976. Bulletin du Cancer, 63 (4) pp. 551-562.
 
Diagnostic immunologique du cancer
Mach J.P., 1975. Schweizerische Medizinische Wochenschrift, 105 (41) pp. 1301-1307.
 
Dépistage humoral du cancer
Mach J.P., 1975. Sozial- und Präventivmedizin, 20 (3-4) pp. 135-141.
 
Human endometrial carcinomas serially transplanted in nude mice and established in continuous cell lines.
Merenda C., Sordat B., Mach J.P., Carrel S., 1975. International Journal of Cancer, 16 (4) pp. 559-570.
 
Identification of a new oncofoetal antigen associated with several types of human carcinomas.
Fritsché R., Mach J.P., 1975. Nature, 258 (5537) pp. 734-737.
Mise au point concernantl'utilisation du dosagede l'antigène carcino-embryonnaire (CEA)en clinique
Mach J.P., 1975. Bulletin du Cancer, 62 (4) pp. 445-452.
 
Relationship between carcinoembryonic antigen and blood group antigens A, B, and Lewis.
Mach J.P., Singh K., Perrinjaquet J., Carrel S., Merenda C., MacDonald D., Holburn A., 1975. Annals of the New York Academy of Sciences, 259 pp. 389-403.
 
Utilité et limites du dosage de l'antigène carcinoembryonnaire (CEA) dans la surveillance postopératoire de malades atteints de carcinomes du côlon et du rectu
Jaeger P., Pettavel J., Wuilleret B., Bertholet M.M., Mach J.P., 1975. Schweizerische Medizinische Wochenschrift, 105 (46) pp. 1533-1538.
Variations of the carcinoembryonic antigen level in the plasma of patients with gynecologie cancers during therapy
Barrelet V., Mach J.P., 1975. American Journal of Obstetrics and Gynecology, 121 (2) pp. 164-168.
 
Cancer et immunité
Cerottini J.C., Mach J.P., 1974. Revue Médicale de la Suisse Romande, 94 (9) pp. 675-684.
 
Carcinoembryonic antigen (CEA). Use and limitations of the CEA radioimmunoassay in the diagnosis and follow-up of colo-rectal carcinoma.
Mach J.P., Pusztaszeri G., MacDonald D., Bertholet M.M., 1974. Johns Hopkins Medical Journal. Supplement, 3 pp. 369-379.
 
Detection of recurrence of large-bowel carcinoma by radioimmunoassay of circulating carcinoembryonic antigen (C.E.A.).
Mach J.P., Jaeger P., Bertholet M.M., Ruegsegger C.H., Loosli R.M., Pettavel J., 1974. Lancet, 304 (7880) pp. 535-540.
 
In vivo localisation of radiolabelled antibodies to carcinoembryonic antigen in human colon carcinoma grafted into nude mice.
Mach J.P., Carrel S., Merenda C., Sordat B., Cerottini J.C., 1974. Nature, 248 (5450) pp. 704-706.
 
Studies of the association of the A, B and Lewis Blood group antigens with carcinoembryonic antigen (CEA).
Holburn A.M., Mach J.P., MacDonald D., Newlands M., 1974. Immunology, 26 (4) pp. 831-843.
Transplantation of a human mammary carcinoma cell line (BT 20) into nude mice.
Ozzello L., Sordat B., Merenda C., Carrel S., Hurlimann J., Mach J.P., 1974. Journal of the National Cancer Institute, 52 (5) pp. 1669-1672.
 
Carcinoembryonic antigen (CEA) in non digestive cancerous and normal tissues.
Pusztaszeri G., Mach J.P., 1973. Immunochemistry, 10 (3) pp. 197-204.
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