Kim Quang Do Cuenod

Publications | Phd and Masters theses

Advanced search is available through Serval

Publications can be managed by accessing Serval via MyUnil


272 publications

In press | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | ...
 
Neurocognition and NMDAR Co-agonists Pathways in Individuals with Treatment Resistant First-Episode Psychosis: a 3-year Follow-up Longitudinal Study
Camporesi S., Xin L., Golay P., Eap C. B., Cleusix M., Cuenod M., Fournier M., Hashimoto K., Jenni R., Ramain J. et al. Molecular Psychiatry. Peer-reviewed.
 
Matrix metalloproteinase 9 (MMP-9) activity, hippocampal extracellular free water, and cognitive deficits are associated with each other in early phase psychosis.
Seitz-Holland J., Alemán-Gómez Y., Cho KIK, Pasternak O., Cleusix M., Jenni R., Baumann P.S., Klauser P., Conus P., Hagmann P. et al. Neuropsychopharmacology. Peer-reviewed.
 
Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis.
Wannan CMJ, Nelson B., Addington J., Allott K., Anticevic A., Arango C., Baker J.T., Bearden C.E., Billah T., Bouix S. et al. Schizophrenia bulletin. Peer-reviewed.
 
Sex-specific interactions between stress axis and redox balance are associated with internalizing symptoms and brain white matter microstructure in adolescents.
Schilliger Z., Alemán-Gómez Y., Magnus Smith M., Celen Z., Meuleman B., Binz P.A., Steullet P., Do K.Q., Conus P., Merglen A. et al., 2024/01/17. Translational psychiatry, 14 (1) p. 30. Peer-reviewed.
 
The Swiss Brain Health Plan 2023–2033
Bassetti Claudio L. A., Heldner Mirjam R., Adorjan Kristina, Albanese Emiliano, Allali Gilles, Arnold Marcel, Bègue Indrit, Bochud Murielle, Chan Andrew, do Cuénod Kim Q. et al., 2023/11/13. Clinical and Translational Neuroscience, 7 (4) p. 38.
 
Developmental changes in cerebral NAD and neuroenergetics of an antioxidant compromised mouse model of schizophrenia.
Skupienski R., Steullet P., Do K.Q., Xin L., 2023/08/05. Translational psychiatry, 13 (1) p. 275. Peer-reviewed.
Towards a youth mental health paradigm: a perspective and roadmap.
Uhlhaas P.J., Davey C.G., Mehta U.M., Shah J., Torous J., Allen N.B., Avenevoli S., Bella-Awusah T., Chanen A., Chen EYH et al., 2023/08. Molecular psychiatry, 28 (8) pp. 3171-3181. Peer-reviewed.
 
Redox and Immune Signaling in Schizophrenia: New Therapeutic Potential.
Dwir D., Khadimallah I., Xin L., Rahman M., Du F., Öngür D., Do K.Q., 2023/05/31. The international journal of neuropsychopharmacology, 26 (5) pp. 309-321. Peer-reviewed.
Characterization of early psychosis patients carrying a genetic vulnerability to redox dysregulation: a computational analysis of mechanism-based gene expression profile in fibroblasts.
Giangreco B., Dwir D., Klauser P., Jenni R., Golay P., Cleusix M., Baumann P.S., Cuénod M., Conus P., Toni N. et al., 2023/05. Molecular psychiatry, 28 (5) pp. 1983-1994. Peer-reviewed.
 
Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis.
Merritt K., McCutcheon R.A., Aleman A., Ashley S., Beck K., Block W., Bloemen OJN, Borgan F., Boules C., Bustillo J.R. et al., 2023/05. Molecular psychiatry, 28 (5) pp. 2039-2048. Peer-reviewed.
 
Validation of the Collaborative Outcomes study on Health and Functioning during Infection Times (COH-FIT) questionnaire for adults.
Solmi M., Thompson T., Estradé A., Agorastos A., Radua J., Cortese S., Dragioti E., Leisch F., Vancampfort D., Thygesen L.C. et al., 2023/04/01. Journal of affective disorders, 326 pp. 249-261. Peer-reviewed.
 
Bridging the gaps towards precision psychiatry: Mechanistic biomarkers for early detection and intervention.
Do K.Q., 2023/03. Psychiatry research, 321 p. 115064. Peer-reviewed.
Low protein-induced intrauterine growth restriction as a risk factor for schizophrenia phenotype in a rat model: assessing the role of oxidative stress and neuroinflammation interaction.
Allgäuer L., Cabungcal J.H., Yzydorczyk C., Do K.Q., Dwir D., 2023/02/01. Translational psychiatry, 13 (1) p. 30. Peer-reviewed.
 
Multimodal Magnetic Resonance Imaging Depicts Widespread and Subregion Specific Anomalies in the Thalamus of Early-Psychosis and Chronic Schizophrenia Patients.
Alemán-Gómez Y., Baumgartner T., Klauser P., Cleusix M., Jenni R., Hagmann P., Conus P., Do K.Q., Bach Cuadra M., Baumann P.S. et al., 2023/01/03. Schizophrenia bulletin, 49 (1) pp. 196-207. Peer-reviewed.
Sleep spindles in people with schizophrenia, schizoaffective disorders or bipolar disorders: a pilot study in a general population-based cohort.
Petit J.M., Strippoli M.F., Stephan A., Ranjbar S., Haba-Rubio J., Solelhac G., Heinzer R., Preisig M., Siclari F., Do K.Q., 2022/12/03. BMC psychiatry, 22 (1) p. 758. Peer-reviewed.
Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium.
Smart S.E., Agbedjro D., Pardiñas A.F., Ajnakina O., Alameda L., Andreassen O.A., Barnes TRE, Berardi D., Camporesi S., Cleusix M. et al., 2022/12. Schizophrenia research, 250 pp. 1-9. Peer-reviewed.
Alterations in TRN-anterodorsal thalamocortical circuits affect sleep architecture and homeostatic processes in oxidative stress vulnerable Gclm<sup>-/-</sup> mice.
Czekus C., Steullet P., Orero López A., Bozic I., Rusterholz T., Bandarabadi M., Do K.Q., Gutierrez Herrera C., 2022/11. Molecular psychiatry, 27 (11) pp. 4394-4406. Peer-reviewed.
Time of exposure to social defeat stress during childhood and adolescence and redox dysregulation on long-lasting behavioral changes, a translational study.
Schnider M., Jenni R., Ramain J., Camporesi S., Golay P., Alameda L., Conus P., Do K.Q., Steullet P., 2022/09/26. Translational psychiatry, 12 (1) p. 413. Peer-reviewed.
Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia; Response to "Adaptive changes to oxidative stress in schizophrenia by Lena Palaniyappan".
Cuenod M., Steullet P., Cabungcal J.H., Dwir D., Khadimallah I., Klauser P., Conus P., Do K.Q., 2022/09. Molecular psychiatry, 27 (9) pp. 3567-3568. Peer-reviewed.
Caught in vicious circles: a perspective on dynamic feed-forward loops driving oxidative stress in schizophrenia.
Cuenod M., Steullet P., Cabungcal J.H., Dwir D., Khadimallah I., Klauser P., Conus P., Do K.Q., 2022/04. Molecular psychiatry, 27 (4) pp. 1886-1897. Peer-reviewed.
Developmental oxidative stress leads to T-type Ca<sup>2+</sup> channel hypofunction in thalamic reticular nucleus of mouse models pertinent to schizophrenia.
El Khoueiry C., Cabungcal J.H., Rovó Z., Fournier M., Do K.Q., Steullet P., 2022/04. Molecular psychiatry, 27 (4) pp. 2042-2051. Peer-reviewed.
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas A.F., Smart S.E., Willcocks I.R., Holmans P.A., Dennison C.A., Lynham A.J., Legge S.E., Baune B.T., Bigdeli T.B., Cairns M.J. et al., 2022/03/01. JAMA psychiatry, 79 (3) pp. 260-269. Peer-reviewed.
Physical and mental health impact of COVID-19 on children, adolescents, and their families: The Collaborative Outcomes study on Health and Functioning during Infection Times - Children and Adolescents (COH-FIT-C&A).
Solmi M., Estradé A., Thompson T., Agorastos A., Radua J., Cortese S., Dragioti E., Leisch F., Vancampfort D., Thygesen L.C. et al., 2022/02/15. Journal of affective disorders, 299 pp. 367-376. Peer-reviewed.
The collaborative outcomes study on health and functioning during infection times in adults (COH-FIT-Adults): Design and methods of an international online survey targeting physical and mental health effects of the COVID-19 pandemic.
Solmi M., Estradé A., Thompson T., Agorastos A., Radua J., Cortese S., Dragioti E., Leisch F., Vancampfort D., Thygesen L.C. et al., 2022/02/15. Journal of affective disorders, 299 pp. 393-407. Peer-reviewed.
Bridging structural MRI with cognitive function for individual level classification of early psychosis via deep learning.
Wen Y., Zhou C., Chen L., Deng Y., Cleusix M., Jenni R., Conus P., Do K.Q., Xin L., 2022. Frontiers in psychiatry, 13 p. 1075564. Peer-reviewed.
Thalamic reticular nucleus impairments and abnormal prefrontal control of dopamine system in a developmental model of schizophrenia: prevention by N-acetylcysteine.
Zhu X., Cabungcal J.H., Cuenod M., Uliana D.L., Do K.Q., Grace A.A., 2021/12. Molecular psychiatry, 26 (12) pp. 7679-7689. Peer-reviewed.
Fronto-Temporal Disconnection Within the Presence Hallucination Network in Psychotic Patients With Passivity Experiences.
Stripeikyte G., Potheegadoo J., Progin P., Rognini G., Blondiaux E., Salomon R., Griffa A., Hagmann P., Faivre N., Do K.Q. et al., 2021/10/21. Schizophrenia bulletin, 47 (6) pp. 1718-1728. Peer-reviewed.
Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis.
Dwir D., Cabungcal J.H., Xin L., Giangreco B., Parietti E., Cleusix M., Jenni R., Klauser P., Conus P., Cuénod M. et al., 2021/10/21. Schizophrenia bulletin, 47 (6) pp. 1782-1794. Peer-reviewed.
Topology predicts long-term functional outcome in early psychosis.
Fournier M., Scolamiero M., Gholam-Rezaee M.M., Cleusix M., Jenni R., Ferrari C., Golay P., Baumann P.S., Cuenod M., Conus P. et al., 2021/09. Molecular psychiatry, 26 (9) pp. 5335-5346. Peer-reviewed.
 
Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data.
Merritt K., McGuire P.K., Egerton A., 1H-MRS in Schizophrenia Investigators, Aleman A., Block W., Bloemen OJN, Borgan F., Bustillo J.R., Capizzano A.A. et al., 2021/06/01. JAMA psychiatry, 78 (6) pp. 667-681. Peer-reviewed.
 
Redox Dysregulation, Myelination Deficit and Dysconnectivity in Schizophrenia: A Translational Study in First Episode Patients and Experimental Models
Do Kim Q., Cabungcal Jan-Harry, Cleusix Martine, Dwir Daniella, Fournier Margot, Griffa Alessandra, Gruetter Rolf, Hagmann Patric, Jenni Raoul, Klauser Paul et al., 2021/05. pp. S56 dans Biological Psychiatry.
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease
Richetin Kevin, Steullet Pascal, Pachoud Mathieu, Perbet Romain, Parietti Enea, Maheswaran Mathischan, Eddarkaoui Sabiha, Bégard Séverine, Pythoud Catherine, Rey Maria et al., 2020/12. Nature Neuroscience, 23 (12) pp. 1567-1579. Peer-reviewed.
MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients.
Dwir D., Giangreco B., Xin L., Tenenbaum L., Cabungcal J.H., Steullet P., Goupil A., Cleusix M., Jenni R., Chtarto A. et al., 2020/11. Molecular psychiatry, 25 (11) pp. 2889-2904. Peer-reviewed.
Partial‐volume modeling reveals reduced gray matter in specific thalamic nuclei early in the time course of psychosis and chronic schizophrenia
Alemán-Gómez Yasser, Najdenovska Elena, Roine Timo, Fartaria Mário João, Canales-Rodríguez Erick J., Rovó Zita, Hagmann Patric, Conus Philippe, Do Kim Q., Klauser Paul et al., 2020/10. Human Brain Mapping, 41 (14) pp. 4041-4061. Peer-reviewed.
In vivo <sup>31</sup>P magnetic resonance spectroscopy study of mouse cerebral NAD content and redox state during neurodevelopment.
Skupienski R., Do K.Q., Xin L., 2020/09/24. Scientific reports, 10 (1) p. 15623. Peer-reviewed.
 
Potential Roles of Redox Dysregulation in the Development of Schizophrenia.
Perkins D.O., Jeffries C.D., Do K.Q., 2020/08/15. Biological psychiatry, 88 (4) pp. 326-336. Peer-reviewed.
 
Early onset of cannabis use and violent behavior in psychosis.
Moulin V., Alameda L., Framorando D., Baumann P.S., Gholam M., Gasser J., Do Cuenod K.Q., Conus P., 2020/07/16. European psychiatry, 63 (1) pp. e78. Peer-reviewed.
Sensorimotor Induction of Auditory Misattribution in Early Psychosis.
Salomon R., Progin P., Griffa A., Rognini G., Do K.Q., Conus P., Marchesotti S., Bernasconi F., Hagmann P., Serino A. et al., 2020/07/08. Schizophrenia bulletin, 46 (4) pp. 947-954. Peer-reviewed.
 
Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention.
Fusar-Poli P., Salazar de Pablo G., Correll C.U., Meyer-Lindenberg A., Millan M.J., Borgwardt S., Galderisi S., Bechdolf A., Pfennig A., Kessing L.V. et al., 2020/07/01. JAMA psychiatry, 77 (7) pp. 755-765. Peer-reviewed.
 
Lactate measurement by neurochemical profiling in the dorsolateral prefrontal cortex at 7T: accuracy, precision, and relaxation times.
Dehghani M., Do K.Q., Magistretti P., Xin L., 2020/06. Magnetic resonance in medicine, 83 (6) pp. 1895-1908. Peer-reviewed.
Psychological trauma occurring during adolescence is associated with an increased risk of greater waist circumference in Early Psychosis patients treated with psychotropic medication.
Alameda L., Levier A., Gholam-Rezaee M., Golay P., Vandenberghe F., Delacretaz A., Baumann P., Glatard A., Dubath C., Herane-Vives A. et al., 2020. PloS one, 15 (12) pp. e0242569. Peer-reviewed.
 
Somatosensory-visual effects in visual biological motion perception.
Progin P., Faivre N., Brooks A., Chang W., Mercier M., Schwabe L., Do K.Q., Blanke O., 2020. PloS one, 15 (6) pp. e0234026. Peer-reviewed.
Stable biomarker identification for predicting schizophrenia in the human connectome.
Gutiérrez-Gómez L., Vohryzek J., Chiêm B., Baumann P.S., Conus P., Cuenod K.D., Hagmann P., Delvenne J.C., 2020. NeuroImage. Clinical, 27 p. 102316. Peer-reviewed.
 
European college of neuropsychopharmacology network on the prevention of mental disorders and mental health promotion (ECNP PMD-MHP).
Fusar-Poli P., Bauer M., Borgwardt S., Bechdolf A., Correll C.U., Do K.Q., Domschke K., Galderisi S., Kessing L.V., Koutsouleris N. et al., 2019/12. European neuropsychopharmacology, 29 (12) pp. 1301-1311. Peer-reviewed.
 
A developmental redox dysregulation leads to spatio-temporal deficit of parvalbumin neuron circuitry in a schizophrenia mouse model.
Cabungcal J.H., Steullet P., Kraftsik R., Cuenod M., Do K.Q., 2019/11. Schizophrenia research, 213 pp. 96-106. Peer-reviewed.
Frontal cortical thickness correlates positively with impulsivity in early psychosis male patients.
Baumann P.S., Klauser P., Griffa A., Golay P., Palix J., Alameda L., Moulin V., Hagmann P., Do K.Q., Conus P., 2019/08. Early intervention in psychiatry, 13 (4) pp. 848-852. Peer-reviewed.
N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study.
Mullier E., Roine T., Griffa A., Xin L., Baumann P.S., Klauser P., Cleusix M., Jenni R., Alemàn-Gómez Y., Gruetter R. et al., 2019/08/01. The international journal of neuropsychopharmacology, 22 (8) pp. 478-487. Peer-reviewed.
 
12.4 THE BODILY SELF IN PSYCHOSIS: SENSORIMOTOR INDUCTION OF AUDITORY MISATTRIBUTION IN PSYCHOSIS IS LINKED TO NEURAL DISCONNECTIVITY
Salomon Roy, Progin Pierre, Griffa Alessandra, Rognini Giulio, Do Kim Q, Conus Philippe, Marchesotti Silvia, Bersconi Fosco, Hagmann Patric, Serino Andrea et al., 2019/04/09. pp. S107-S108 dans Schizophrenia Bulletin. Peer-reviewed.
Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging.
Griffa A., Baumann P.S., Klauser P., Mullier E., Cleusix M., Jenni R., van den Heuvel M.P., Do K.Q., Conus P., Hagmann P., 2019/02/04. Translational psychiatry, 9 (1) p. 62. Peer-reviewed.
Nutritional Intervention for Developmental Brain Damage: Effects of Lactoferrin Supplementation in Hypocaloric Induced Intrauterine Growth Restriction Rat Pups.
van de Looij Y., Larpin C., Cabungcal J.H., Sanches E.F., Toulotte A., Do K.Q., Sizonenko S.V., 2019. Frontiers in endocrinology, 10 p. 46. Peer-reviewed.
S.11.03 Similar anomalies in the thalamic reticular nucleus of a mice model of redox dysregulation and of schizophrenia patients
Steullet P., Cabungcal J.H., Bukhari S., Pantazopoulos H., Cuénod M., Berretta S., Do K.Q., 2019. European Neuropsychopharmacology, 29 pp. S16.
Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis.
Alameda L., Fournier M., Khadimallah I., Griffa A., Cleusix M., Jenni R., Ferrari C., Klauser P., Baumann P.S., Cuenod M. et al., 2018/12/04. Proceedings of the National Academy of Sciences of the United States of America, 115 (49) pp. 12495-12500. Peer-reviewed.
Patients participating to neurobiological research in early psychosis: A selected subgroup?
Golay P., Baumann P.S., Jenni R., Do K.Q., Conus P., 2018/11. Schizophrenia research, 201 pp. 249-253. Peer-reviewed.
N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial.
Klauser P., Xin L., Fournier M., Griffa A., Cleusix M., Jenni R., Cuenod M., Gruetter R., Hagmann P., Conus P. et al., 2018/10/12. Translational psychiatry, 8 (1) p. 220. Peer-reviewed.
The thalamic reticular nucleus in schizophrenia and bipolar disorder: role of parvalbumin-expressing neuron networks and oxidative stress.
Steullet P., Cabungcal J.H., Bukhari S.A., Ardelt M.I., Pantazopoulos H., Hamati F., Salt T.E., Cuenod M., Do K.Q., Berretta S., 2018/10. Molecular psychiatry, 23 (10) pp. 2057-2065. Peer-reviewed.
Networks of blood proteins in the neuroimmunology of schizophrenia.
Jeffries C.D., Perkins D.O., Fournier M., Do K.Q., Cuenod M., Khadimallah I., Domenici E., Addington J., Bearden C.E., Cadenhead K.S. et al., 2018/06/06. Translational psychiatry, 8 (1) p. 112. Peer-reviewed.
 
T221. Sensorimotor Induction of Auditory Misattribution in Psychosis is Linked to Neural Disconnectivity
Salomon Roy, Progin Pierre, Griffa Alessandra, Rognini Giulio, Do Kim Q., Conus Philippe, Marchesotti Silvia, Hagmann Patric, Serino Andrea, Blanke Olaf, 2018/05. pp. S214 dans Biological Psychiatry. Peer-reviewed.
 
10.2 REDOX DYSREGULATION, OLIGODENDROCYTES AND WHITE MATTER ALTERATIONS IN SCHIZOPHRENIA
Klauser Paul, Baumann Philipp S, Fournier Margot, Xin Lijing, Griffa Alessandra, Cleusix Martine, Jenni Raoul, Cuenod Michel, Hagmann Patric, Conus Philippe et al., 2018/04/01. pp. S15-S16 dans Schizophrenia Bulletin. Peer-reviewed.
 
16.2 CHILDHOOD TRAUMA ENGAGES OXIDATIVE STRESS, HIPPOCAMPUS ALTERATIONS, AND POORER CLINICAL OUTCOME IN EARLY PSYCHOSIS PATIENTS
Alameda Luis, Fournier Margot, Khadimallah Ines, Baumann Philippe S, Cleusix Martine, Griffa Alessandra, Klauser Paul, Jenni Raoul, Cuenod Michel, Hagmann Patric et al., 2018/04/01. pp. S25-S26 dans Schizophrenia Bulletin. Peer-reviewed.
 
F152. N-ACETYL-CYSTEINE SUPPLEMENTATION IMPROVES FUNCTIONAL CONNECTIVITY IN THE CINGULATE CORTEX IN EARLY PSYCHOSIS
Mullier Emeline, Roine Timo, Griffa Alessandra, Baumann Philipp S, Klauser Paul, Conus Philippe, Do Kim Q, Hagmann Patric, 2018/04/01. pp. S279-S279 dans Schizophrenia Bulletin. Peer-reviewed.
 
T52. N-ACETYL-CYSTEINE ADD-ON TREATMENT LEADS TO AN IMPROVEMENT OF FORNIX WHITE MATTER INTEGRITY IN EARLY PSYCHOSIS
Klauser Paul, Xin Lijing, Fournier Margot, Griffa Alessandra, Cleusix Martine, Jenni Raoul, Cuenod Michel, Gruetter Rolf, Hagmann Patric, Conus Philippe et al., 2018/04/01. pp. S133-S134 dans Schizophrenia Bulletin. Peer-reviewed.
 
Impulsivity in early psychosis: A complex link with violent behaviour and a target for intervention.
Moulin V., Golay P., Palix J., Baumann P.S., Gholamrezaee M.M., Azzola A., Gasser J., Do K.Q., Alameda L., Conus P., 2018/03. European psychiatry, 49 pp. 30-36. Peer-reviewed.
N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis.
Conus P., Seidman L.J., Fournier M., Xin L., Cleusix M., Baumann P.S., Ferrari C., Cousins A., Alameda L., Gholam-Rezaee M. et al., 2018/02/15. Schizophrenia bulletin, 44 (2) pp. 317-327. Peer-reviewed.
A lack of GluN2A-containing NMDA receptors confers a vulnerability to redox dysregulation: Consequences on parvalbumin interneurons, and their perineuronal nets.
Cardis R., Cabungcal J.H., Dwir D., Do K.Q., Steullet P., 2018/01. Neurobiology of disease, 109 (Pt A) pp. 64-75. Peer-reviewed.
 
Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex.
Rigucci S., Xin L., Klauser P., Baumann P.S., Alameda L., Cleusix M., Jenni R., Ferrari C., Pompili M., Gruetter R. et al., 2018/01. Psychopharmacology, 235 (1) pp. 13-22. Peer-reviewed.
Treatment in early psychosis with N-acetyl-cysteine for 6 months improves low-level auditory processing: Pilot study.
Retsa C., Knebel J.F., Geiser E., Ferrari C., Jenni R., Fournier M., Alameda L., Baumann P.S., Clarke S., Conus P. et al., 2018/01. Schizophrenia research, 191 pp. 80-86. Peer-reviewed.
 
Dysfunction of the redox-sensitive transcription factor Nrf2 in vulnerable animals.
Bouvier E., Brouillard F., Molet J., Claverie D., Cabungcal J.H., Cresto N., Doligez N., Rivat C., Do K.Q., Bernard C. et al., 2017/12..
Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression.
Bouvier E., Brouillard F., Molet J., Claverie D., Cabungcal J.H., Cresto N., Doligez N., Rivat C., Do K.Q., Bernard C. et al., 2017/12. Molecular psychiatry, 22 (12) pp. 1701-1713. Peer-reviewed.
The coupling of low-level auditory dysfunction and oxidative stress in psychosis patients.
Geiser E., Retsa C., Knebel J.F., Ferrari C., Jenni R., Fournier M., Alameda L., Baumann P.S., Clarke S., Conus P. et al., 2017/12. Schizophrenia research, 190 pp. 52-59. Peer-reviewed.
Implication of the glutamate-cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis.
Fournier M., Monin A., Ferrari C., Baumann P.S., Conus P., Do K., 2017/09/18. NPJ schizophrenia, 3 (1) p. 31. Peer-reviewed.
Mild Depressive Symptoms Mediate the Impact of Childhood Trauma on Long-Term Functional Outcome in Early Psychosis Patients.
Alameda L., Golay P., Baumann P.S., Progin P., Mebdouhi N., Elowe J., Ferrari C., Do K.Q., Conus P., 2017/09/01. Schizophrenia bulletin, 43 (5) pp. 1027-1035. Peer-reviewed.
Social isolation stress and chronic glutathione deficiency have a common effect on the glutamine-to-glutamate ratio and myo-inositol concentration in the mouse frontal cortex.
Corcoba A., Gruetter R., Do K.Q., Duarte JMN, 2017/09. Journal of neurochemistry, 142 (5) pp. 767-775. Peer-reviewed.
Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.
Steullet P., Cabungcal J.H., Coyle J., Didriksen M., Gill K., Grace A.A., Hensch T.K., LaMantia A.S., Lindemann L., Maynard T.M. et al., 2017/07. Molecular psychiatry, 22 (7) pp. 936-943. Peer-reviewed.
 
Potential mechanisms of development-dependent adverse effects of the herbicide paraquat in 3D rat brain cell cultures.
Sandström J., Broyer A., Zoia D., Schilt C., Greggio C., Fournier M., Do K.Q., Monnet-Tschudi F., 2017/05. Neurotoxicology, 60 pp. 116-124. Peer-reviewed.
 
N-acetyl-cysteine in a double-blind randomized placebo-controlled trial: Towards biomarker guided treatment in early psychosis
Conus P., Fournier M., Xin L., Baumann P., Ferrari C., Cousins A., Alameda L., Golay P., Jenni R., Kashavan M.S. et al., 2017/04. pp. S806 dans European Psychiatry, Elsevier BV.
 
SA19. N-Acetyl-Cysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis
Do Kim, Seidman Larry J., Fournier Margot, Xin Lijing, Cleusix Martine, Baumann Philipp S., Ferrari Carina, Cousins Ann, Alameda Luis, Gholam-Rezaee Mehdi et al., 2017/03/01. pp. S119-S120 dans Schizophrenia Bulletin, Oxford University Press (OUP).
Tollip, an early regulator of the acute inflammatory response in the substantia nigra.
Humbert-Claude M., Duc D., Dwir D., Thieren L., Sandström von Tobel J., Begka C., Legueux F., Velin D., Maillard M.H., Do K.Q. et al., 2016/12/07. Journal of neuroinflammation, 13 (1) p. 303. Peer-reviewed.
Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis.
Xin L., Mekle R., Fournier M., Baumann P.S., Ferrari C., Alameda L., Jenni R., Lu H., Schaller B., Cuenod M. et al., 2016/09. Schizophrenia bulletin, 42 (5) pp. 1185-1196. Peer-reviewed.
Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A "central hub" in schizophrenia pathophysiology?
Steullet P., Cabungcal J.H., Monin A., Dwir D., O'Donnell P., Cuenod M., Do K.Q., 2016/09. Schizophrenia research, 176 (1) pp. 41-51. Peer-reviewed.
Impaired fornix-hippocampus integrity is linked to peripheral glutathione peroxidase in early psychosis.
Baumann P.S., Griffa A., Fournier M., Golay P., Ferrari C., Alameda L., Cuenod M., Thiran J.P., Hagmann P., Do K.Q. et al., 2016/07/26. Translational psychiatry, 6 (7) pp. e859. Peer-reviewed.
EEG oscillations link impulsivity and aggression in early phase psychosis
Palix Julie, Knebel Jean-François, Murray Micah M., Baumann Philipp, Alameda Luis, 2016/06/26. dans Organization for Human Brain Mapping 2016. Peer-reviewed.
 
Age at the time of exposure to trauma modulates the psychopathological profile in early psychosis patients
Alameda L., Golay P., Baumann P., Ferrari C., Do K.Q., Conus P., 2016/05. Journal of Clinical Psychiatry, 77 (5) pp. e612-e618. Peer-reviewed.
Frontal cortical thickness correlates positively with impulsivity in early psychosis patients
Baumann P. S., Klauser P., Griffa A., Palix J., Azzola A., Alameda L., Jenni R., Hagmann P., Gasser J., Conus P. et al., 2016/04. dans NCCR-Synapsy 2016 Neurobiologie de la santé mentale.. Peer-reviewed.
Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia.
Zhang Y., Hodgson N.W., Trivedi M.S., Abdolmaleky H.M., Fournier M., Cuenod M., Do K.Q., Deth R.C., 2016. Plos One, 11 (1) pp. e0146797. Peer-reviewed.
Glutamate Cysteine Ligase-Modulatory Subunit Knockout Mouse Shows Normal Insulin Sensitivity but Reduced Liver Glycogen Storage.
Lavoie S., Steullet P., Kulak A., Preitner F., Do K.Q., Magistretti P.J., 2016. Frontiers in Physiology, 7 p. 142. Peer-reviewed.
Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis.
Hardingham G.E., Do K.Q., 2016. Nature Reviews. Neuroscience, 17 (2) pp. 125-134. Peer-reviewed.
 
Benefits of adjunctive N-acetylcysteine in a sub-group of clozapine-treated individuals diagnosed with schizophrenia.
Dean O.M., Mancuso S.G., Bush A.I., Copolov D., Do K.Q., Cuénod M., Conus P., Rossell S.L., Castle D.J., Berk M., 2015/12/30. Psychiatry research, 230 (3) pp. 982-983. Peer-reviewed.
Glutathione Deficit Affects the Integrity and Function of the Fimbria/Fornix and Anterior Commissure in Mice: Relevance for Schizophrenia.
Corcoba A., Steullet P., Duarte J.M., Van de Looij Y., Monin A., Cuenod M., Gruetter R., Do K.Q., 2015/10/03. The international journal of neuropsychopharmacology, 19 (3) pp. pyv110. Peer-reviewed.
Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients.
Monin A., Baumann P.S., Griffa A., Xin L., Mekle R., Fournier M., Butticaz C., Klaey M., Cabungcal J.H., Steullet P. et al., 2015/07. Molecular psychiatry, 20 (7) pp. 827-838. Peer-reviewed.
 
Characterizing the connectome in schizophrenia with diffusion spectrum imaging.
Griffa A., Baumann P.S., Ferrari C., Do K.Q., Conus P., Thiran J.P., Hagmann P., 2015/01. Human Brain Mapping, 36 (1) pp. 354-366. Peer-reviewed.
 
Childhood sexual and physical abuse: age at exposure modulates impact on functional outcome in early psychosis patients.
Alameda L., Ferrari C., Baumann P.S., Gholam-Rezaee M., Do K.Q., Conus P., 2015. Psychological Medicine, 45 (13) pp. 2727-2736. Peer-reviewed.
Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin.
Rossier J., Bernard A., Cabungcal J.H., Perrenoud Q., Savoye A., Gallopin T., Hawrylycz M., Cuénod M., Do K., Urban A. et al., 2015. Molecular Psychiatry, 20 (2) pp. 154-161. Peer-reviewed.
 
Inflammation in schizophrenia: A question of balance.
Leza J.C., García-Bueno B., Bioque M., Arango C., Parellada M., Do K., O'Donnell P., Bernardo M., 2015. Neuroscience and Biobehavioral Reviews, 55 pp. 612-626. Peer-reviewed.
 
Prolonged Period of Cortical Plasticity upon Redox Dysregulation in Fast-Spiking Interneurons.
Morishita H., Cabungcal J.H., Chen Y., Do K.Q., Hensch T.K., 2015. Biological Psychiatry, 78 (6) pp. 396-402. Peer-reviewed.
 
Role of redox dysregulation in white matter anomalies associated with schizophrenia
Monin A., Fournier M., Baumann P.S., Cuenod M., Do K.Q., 2015. pp. 481-500 dans Pletnikov Mikhail V., Waddington John L. (eds.) Modeling the Psychopathological Dimensions of Schizophrenia : From Molecules to Behavior chap. 28, Elsevier Science.
 
Targeting Oxidative Stress and Aberrant Critical Period Plasticity in the Developmental Trajectory to Schizophrenia.
Do K.Q., Cuenod M., Hensch T.K., 2015. Schizophrenia Bulletin, 41 (4) pp. 835-846. Peer-reviewed.
 
Defect of the Perineuronal Nets Enwrapping Parvalbumin Interneurons in a Mouse Model of Schizophrenia can be Prevented by N-acetylcysteine
Cabungcal Jan-Harry, Steullet Pascal, Cottier Adeline, Cuenod Michel, Q. Do. Kim , 2014. pp. 176-177 dans Biological Psychiatry. Peer-reviewed.
 
Evaluation of Redox Dysregulation in the Pathology of Schizophrenia Using Induced Pluripotent Stem Cell Technology
Giangreco Basilio, Steullet Pascal, Cabungcal Jan-Harry, Bartesaghi Luca, Toni Nicolas, Chrast Roman, Q. Do. Kim , 2014. p. 186 dans Biological Psychiatry. Peer-reviewed.
Fast oscillatory activity in the anterior cingulate cortex: dopaminergic modulation and effect of perineuronal net loss.
Steullet P., Cabungcal J.H., Cuénod M., Do K.Q., 2014. Frontiers in Cellular Neuroscience, 8 p. 244. Peer-reviewed.
 
Genetic Association with Prefrontal Glutathione Deficit: A 3T 1H MRS Study in Early Psychosis
Xin L., Mekle R., Ferrari C., Baumann PS., Alameda L., Moser H., Fournier M., Lu H., Conus P., Gruetter R. et al., 2014. pp. 108-109 dans Biological Psychiatry, Supplement. Peer-reviewed.
 
Glutathione Deficit Affects White Matter Integrity in Prefrontal Cortex and Impairs Brain Connectivity in Schizophrenia
Monin A, Baumann P, Griffa Alessandra, Xin Lijing, Mekle Ralf, Fournier Margot, Cabungcal Jan-Harry, Steullet Pascal, Butticaz Christophe, Ferrari Carina et al., 2014. p. 185 dans Biological Psychiatry. Peer-reviewed.
 
Impaired metabolic reactivity to oxidative stress in early psychosis patients
Fournier M., Ferrari C., Baumann PS., Monin A., Moser H., Pappan KL ., Cuenod M., Conus P., Do KQ, 2014. p. 272 dans Biological Psychiatry.
 
Impaired metabolic reactivity to oxidative stress in early psychosis patients.
Fournier M., Ferrari C., Baumann P.S., Polari A., Monin A., Bellier-Teichmann T., Wulff J., Pappan K.L., Cuenod M., Conus P. et al., 2014. Schizophrenia Bulletin, 40 (5) pp. 973-983. Peer-reviewed.
 
Impaired White Matter Integrity in Fornix and Anterior Commissure in a Schizophrenia Mouse Model of Redox Dysregulation
Corcoba Alberto, Steullet Pascal, Duarte João M.N., Van de Looij Yohan, Gruetter Rolf, Q. Do. Kim , 2014. p. 175 dans Biological Psychiatry. Peer-reviewed.
 
Integrity of the fornix and hippocampus and relationship with peripheral oxidative stress markers in early phase psychosis
Baumann PS, Griffa A., Ferrari C., Alameda L., Thiran JP., Do KQ., Hagmann P., Conus P., 2014. p. 109 dans Biological Psychiatry. Peer-reviewed.
 
Involvement of the Receptor for Advanced Glycation End-product (RAGE) in Redox Dysregulation and Neuroinflammation in an Animal Model of Schizophrenia
Dwir Daniella, Cabungcal Jan-Harry, Steullet Pascal, Fournier Margot, Tirouvanziam Rabindra, Q. Do. Kim , 2014. pp. 185-186 dans Biological Psychiatry. Peer-reviewed.
Juvenile antioxidant treatment prevents adult deficits in a developmental model of schizophrenia.
Cabungcal J.H., Counotte D.S., Lewis E.M., Tejeda H.A., Piantadosi P., Pollock C., Calhoon G.G., Sullivan E.M., Presgraves E., Kil J. et al., 2014. Neuron, 83 (5) pp. 1073-1084. Peer-reviewed.
 
Longitudinal neurochemical modifications in the aging mouse brain measured in vivo by (1)H magnetic resonance spectroscopy.
Duarte J.M., Do K.Q., Gruetter R., 2014. Neurobiology of Aging, 35 (7) pp. 1660-1668. Peer-reviewed.
 
Oxidative/Nitrosative stress in psychiatric disorders: are we there yet?
O'Donnell P., Do K.Q., Arango C., 2014. Schizophrenia Bulletin, 40 (5) pp. 960-962. Peer-reviewed.
 
Sexual and physical trauma and the social and vocational functioning in first-episode psychosis patients
Alameda L., Baumann PS., Ferrari C., Fournier M., Moser H., Gholam-Razaee MM., Do KQ., Conus P., 2014. p. 342 dans Biological Psychiatry. Peer-reviewed.
 
Early-Life Insults Impair Parvalbumin Interneurons via Oxidative Stress: Reversal by N-Acetylcysteine.
Cabungcal J.H., Steullet P., Kraftsik R., Cuenod M., Do K.Q., 2013. Biological Psychiatry, 73 (6) pp. 574-582. Peer-reviewed.
 
Gènes, environnement et neurodéveloppement: te cas de la schizophrénie [Schizophrenia: genes, environment and neurodevelopment].
Do K.Q., 2013. Revue Médicale Suisse, 9 (398) pp. 1672, 1674-1672, 1677. Peer-reviewed.
 
Perineuronal nets protect fast-spiking interneurons against oxidative stress.
Cabungcal J.H., Steullet P., Morishita H., Kraftsik R., Cuenod M., Hensch T.K., Do K.Q., 2013. Proceedings of the National Academy of Sciences of the United States of America, 110 (22) pp. 9130-9135. Peer-reviewed.
 
Redox dysregulation in the pathophysiology of schizophrenia and bipolar disorder: insights from animal models.
Kulak A., Steullet P., Cabungcal J.H., Werge T., Ingason A., Cuenod M., Do K.Q., 2013. Antioxidants and Redox Signaling, 18 (12) pp. 1428-1443. Peer-reviewed.
 
Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne): implementation of an early intervention programme for psychosis in Switzerland.
Baumann P.S., Crespi S., Marion-Veyron R., Solida A., Thonney J., Favrod J., Bonsack C., Do K.Q., Conus P., 2013. Early Intervention In Psychiatry, 7 (3) pp. 322-328. Peer-reviewed.
 
Behavioral phenotyping of glutathione-deficient mice: Relevance to schizophrenia and bipolar disorder.
Kulak A., Cuenod M., Do K.Q., 2012. Behavioural Brain Research, 226 (2) pp. 563-70. Peer-reviewed.
 
Glutathione Deficit and Xct in Schizophrenia: Modulation of Neurochemical Profile by N-Acetylcysteine in Mouse Model
Do K.Q., 2012. pp. 270S-270S dans 67th Annual Scientific Convention and Meeting of the Society-of-Biological-Psychiatry, Biological psychiatry. Peer-reviewed.
Glutathione precursor N-acetyl-cysteine modulates EEG synchronization in schizophrenia patients: a double-blind, randomized, placebo-controlled trial.
Carmeli C., Knyazeva M.G., Cuénod M., Do K.Q., 2012. Plos One, 7 (2) pp. e29341. Peer-reviewed.
 
High b-value diffusion-weighted imaging: A sensitive method to reveal white matter differences in schizophrenia.
Baumann P.S., Cammoun L., Conus P., Do K.Q., Marquet P., Meskaldji D., Meuli R., Thiran J.P., Hagmann P., 2012. Psychiatry Research, 201 (2) pp. 144-151. Peer-reviewed.
 
Investigating the Joined Effects of Genetically Compromized Antioxidant System and Peripubertal Stress on Stress Hormone Levels and Behavior in Mice
Kulak Anita, Marquez Cristina, Sandi Carmen, Do Kim, 2012. p. 39 dans Biological Psychiatry. Peer-reviewed.
 
Investigation of Network Metrics Correlation with Frontal Glutathione Levels in Control and First Episode Psychosis Subjects
Griffa Alessandra, Baumann Philipp S., Xin Lijing, Crespi Sara, Ferrari Carina, Thiran Jean-Philippe, Gruetter Rolf, Do Kim Q., Conus Philippe, Hagmann Patric, 2012. pp. 254S dans 67th Annual Scientific Convention and Meeting, Biological Psychiatry. Peer-reviewed.
 
Mapping the human connectome at multiple scales with diffusion spectrum MRI.
Cammoun L., Gigandet X., Meskaldji D., Thiran J.P., Sporns O., Do K.Q., Maeder P., Meuli R., Hagmann P., 2012. Journal of Neuroscience Methods, 203 (2) pp. 386-397. Peer-reviewed.
 
MRS Frontal Glutathione Levels Correlate with DSI White Matter Integrity Measure in Control Subjects but Not in Early Psychosis Patients
Baumann Philipp S., Griffa Alessandra, Xin Lijing, Crespi Sara, Ferrari Carina, Thiran Jean-Philippe, Gruetter Rolf, Hagmann Patric, Do Kim Quang, Conus Philippe, 2012. pp. 259S dans 67th Annual Scientific Convention and Meeting, Biological Psychiatry. Peer-reviewed.
 
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
das Neves Duarte J.M., Kulak A., Gholam-Razaee M.M., Cuenod M., Gruetter R., Do K.Q., 2012. Biological Psychiatry, 71 (11) pp. 1006-1014. Peer-reviewed.
 
Redox dysregulation affects proliferation, differentiation of oligodendrocyte progenitors and myelination: relevance to dysconnectivity in schizophrenia
Do Kim, 2012. p. 4 dans Biological Psychiatry. Peer-reviewed.
Altered glycogen metabolism in cultured astrocytes from mice with chronic glutathione deficit; relevance for neuroenergetics in schizophrenia.
Lavoie S., Allaman I., Petit J.M., Do K.Q., Magistretti P.J., 2011. Plos One, 6 (7) pp. e22875. Peer-reviewed.
 
Altered Local Beta and Gamma Synchronization in Prefrontal Cortex of Mice with Redox Dysregulation or Maternal Immune Activation
Steullet P., Cabungcal J.H., Meyer U., Cuenod M., Do K.Q., 2011. pp. 121S dans 66th Annual Meeting of the Society of Biological Psychiatry, Biological Psychiatry. Peer-reviewed.
 
Genetic dysregulation of glutathione synthesis predicts alteration of plasma thiol redox status in schizophrenia.
Gysin R., Kraftsik R., Boulat O., Bovet P., Conus P., Comte-Krieger E., Polari A., Steullet P., Preisig M., Teichmann T. et al., 2011. Antioxidants and Redox Signaling, 15 (7) pp. 2003-2010. Peer-reviewed.
 
Glutathione deficit and redox dysregulation in animal models of schizophrenia
Steullet Pascal, Cabungcal Jan-Harry, Kulak Anita, Cuenod Michel, Schenk Françoise, Do Cuenod Kim, 2011. pp. 149-188 dans O'Donnell Patricio (eds.) Animal models of schizophrenia and related disorders chap. 7, Humana Press/Springer.
 
High b-value Diffusion-weighted Imaging: A Sensitive Method to Reveal White Matter Changes in Schizophrenia
Baumann P.S., Cammoun L., Conus P., Do K.Q., Marquet P., Meskaldji D., Meuli R., Thiran J.P., Hagmann P., 2011. pp. 257S dans 66th Annual Meeting of the Society of Biological Psychiatry, Biological Psychiatry. Peer-reviewed.
 
Interaction of GAG trinucleotide repeat and C-129T polymorphisms impairs expression of the glutamate-cysteine ligase catalytic subunit gene.
Butticaz C., Gysin R., Cuénod M., Do K.Q., 2011. Free Radical Biology and Medicine, 50 (5) pp. 617-623. Peer-reviewed.
 
Oxidative stress and schizophrenia: 1H-MRS at 14.1 T in developing mice with glutathione deficit
Do Kim Q, Duarte J.M., Kulak A., Cuenod M., Gruetter R., 2011. p. 123 dans 13th International Congress on Schizophrenia Research (ICOSR), Schizophrenia Bulletin. Peer-reviewed.
 
Oxidative stress during development in prefrontal cortical interneurons in developmental animal models of schizophrenia
O'Donnell ., Cabungcal H.J., Piantadosi P., Lewis E., Calhoon G.G., Do K., 2011. p. 111 dans 13th International Congress on Schizophrenia Research (ICSR), Schizophrenia Bulletin. Peer-reviewed.
 
Redox dysregulation and oxidative stress affects parvalbumin interneurons and neural synchrony in anterior cingulate cortex during neurodevelopment
Cuenod M., Cabungcal J.H., Kulak A., Steullet P., Do K., 2011. p. 102 dans 13th International Congress on Schizophrenia Research (ICSR), Schizophrenia Bulletin. Peer-reviewed.
 
Attenuated asymmetry of functional connectivity in schizophrenia: a high-resolution EEG study.
Jalili M., Meuli R., Do K.Q., Hasler M., Crow T.J., Knyazeva M.G., 2010. Psychophysiology, 47 (4) pp. 706-716. Peer-reviewed.
 
Global and local connectivity changes in schizophrenia investigated by diffusion connectome
Cammoun Leila, Meskaldji Djalel, Gigandet Xavier, Thiran Jean Philippe, Meuli Reto, Cuenod Michel, Hagmann Patric, Do Thi Kim, 2010. p. 224 dans 2nd Conference of the Schizophrenia International Research Society (SIRS), Schizophrenia Research. Peer-reviewed.
 
Glutathione Precursor, N-Acetyl-Cysteine, Modulates EEG Synchronization in Schizophrenia Patients
Carmeli Cristian, Knyazeva Maria G., Cuenod Michel, Do Kim Q., 2010. pp. 263S-264S dans 65th Annual Convention of the Society of Biological Psychiatry, Biological Psychiatry. Peer-reviewed.
 
Increased eeg synchronization in schizophrenia patients by the glutathione precursor, n-acetyl-cysteine
Carmeli Cristian, Knyazeva Maria G., Cuenod Michel, Do Kim Q., 2010. pp. 245-246 dans 2nd Conference of the Schizophrenia-International-Research-Society (SIRS), Schizophrenia Research. Peer-reviewed.
 
Metabolic alterations in the cortex of a mouse model with glutathione deficit - relevance to schizophrenia
Duarte Joao M. N., Kulak Anita, Gruetter Rolf, Do Kim Q., 2010. p. 201 dans 2nd Conference of the Schizophrenia-International-Research-Society (SIRS), Schizophrenia Research. Peer-reviewed.
 
Neurochemical profile of the developing mouse cortex determined by in vivo 1H NMR spectroscopy at 14.1 T and the effect of recurrent anaesthesia.
Kulak A., Duarte J.M., Do K.Q., Gruetter R., 2010. Journal of Neurochemistry, 115 (6) pp. 1466-1477. Peer-reviewed.
New therapies targeting antioxidant defense and membrane integrity in schizophrenia: a prevention perspective
Lavoie Suzie, Amminger Paul, Berk Michael, Do Kim, McGorry Pat, 2010. pp. A19 dans 11th Australasian Schizophrenia Conference, Australian and New Zealand Journal of Psychiatry. Peer-reviewed.
 
Quel rôle pour les neurosciences dans l'amélioration du traitement de la phase précoce des troubles psychotiques ?: exemple de l'hypothèse de la dysrégulation glutathion/redox dans la schizophrénie
Conus Philippe, Do Kim Q., 2010. Information psychiatrique, 86 (6) pp. 484-492.
 
Redox dysregulation affects parvalbumine interneuron's integrity and neural synchronisation in ventral but not dorsal hippocampus
Cabungcal Jan-Harry, Steullet Pascal, Frank Anita, Kraftsik Rudolf, Ying Chen, Dalton Timothy P., Cuenod Michel, Do Kim Q., 2010. p. 388 dans 2nd Biennial Schizophrenia International Research Conference, Schizophrenia Research. Peer-reviewed.
Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors.
Steullet P., Cabungcal J.H., Kulak A., Kraftsik R., Chen Y., Dalton T.P., Cuenod M., Do K.Q., 2010. Journal of Neuroscience, 30 (7) pp. 2547-2558. Peer-reviewed.
 
Redox dysregulation and oxidative stress in schizophrenia: nutrigenetics as a challenge in psychiatric disease prevention.
Do K.Q., Conus P., Cuenod M., 2010. World Review of Nutrition and Dietetics, 101 pp. 131-153. Peer-reviewed.
 
Redox dysregulation and oxidative stress in schizophrenia: nutrigenetics as a challenge in psychiatric disease prevention.
Do K.Q., Conus P., Cuenod M., 2010. Journal of Nutrigenetics and Nutrigenomics, 3 (4-6) pp. 267-289. Peer-reviewed.
 
Skin fibroblast model to study an impaired glutathione synthesis: consequences of a genetic polymorphism on the proteome.
Gysin R., Riederer I.M., Cuénod M., Do K.Q., Riederer B.M., 2009/04/06. Brain research bulletin, 79 (1) pp. 46-52. Peer-reviewed.
 
A developmental in vivo 1H NMR study in mice with genetic redox dysregulation: an animal model with relevance to schizophrenia
Frank A., Duarte J.M., Do K.Q., Gruetter R., 2009. p. 97 dans 22nd Biennial Meeting of the International-Society-of-Neurochemistry/Asian-Pacific-Society-for-Neurochemistry, Busan, South Korea, August 23-29, 2009, Journal of Neurochemistry. Peer-reviewed.
 
Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.
Lavoie S., Chen Y., Dalton T.P., Gysin R., Cuénod M., Steullet P., Do K.Q., 2009. Journal of Neurochemistry, 108 (6) pp. 1410-1422. Peer-reviewed.
 
Detection of glutathione with high precision in the anterior cingulate using short TE 1H MRS at 3T
Meckle R., Gambarotta G., Teichmann T., Chevrey N., Browaeys P., Meuli R., Michel C., Do K., Cuenod M., Gruetter R., 2009. dans CIBM-CHUV MR Research Meeting.
 
Developmental critical period in gentic redox dysregulation: animal and human studies in schizophrenia
Do Kim Q., Conus P., Bovet P., Cabungcal J.H., Frank A., Gysin R., Lavoie S., Polari A., Steullet P., Teichmann T. et al., 2009. pp. 106-107 dans 12th International Congress on Schizophrenia Research, San Diego, CA, March 28-April 01, 2009, Schizophrenia Bulletin. Peer-reviewed.
 
Early glutathione deficit impairs parvalbumin expression in gaba interneurons and kainate-induced gamma oscillations
Cabungcal J.H., Steullet P., Frank A., Chen Y., Cuenod M., Do K.Q., 2009. pp. 136-137 dans 12th International Congress on Schizophrenia Research, San Diego, CA, March 28-April 01, 2009, Schizophrenia Bulletin. Peer-reviewed.
 
Genetic redox dysregulation induces behavioural deficits in the adult mouse: an animal model for schizophrenia
Frank A., Dalton T., Chen Y., Cuenod M., Do K.Q., 2009. p. 61 dans Annual Conference of the Swiss Society of Sleep Research, Sleep Medicine and Chronobiology (SSSSC) and the Swiss Society of Biological Psychiatry (SSBP), Bern, March 25 and 26, 2009, Neuropsychobiology. Peer-reviewed.
 
Mutation screening of the glutamate cysteine ligase modifier (GCLM) gene in patients with schizophrenia.
Butticaz C., Werge T., Beckmann J.S., Cuénod M., Do K.Q., Rivolta C., 2009. Psychiatric genetics, 19 (4) pp. 201-8. Peer-reviewed.
 
Redox dysregulation in schizophrenia: Genetic susceptibility and pathophysiological mechanisms, Handbook of neurochemistry and molecular neurobiology
Do KQ, Bovet P, Cabungcal JH, Conus P, Gysin R, Lavoie S, Steullet P, Cuenod M, 2009. pp. 286-311 dans Lajtha Abel (eds.) Handbook of neurochemistry and molecular neurobiology, Springer Science+Business Media.
 
Redox dysregulation, neurodevelopment, and schizophrenia.
Do K.Q., Cabungcal J.H., Frank A., Steullet P., Cuenod M., 2009. Current opinion in neurobiology, 19 (2) pp. 220-30. Peer-reviewed.
 
A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons
Steullet Pascal, Lavoie Suzie, Kraftsik Rudolf, Guidi Raffaella, Gysin René, Cuénod Michel, Do Kim Q., 2008. Free Radical Biology & Medicine, 44 (6) pp. 1042-1054. Peer-reviewed.
 
Alpha rhythm and hypofrontality in schizophrenia
Knyazeva M. G., Jalili M., Meuli R., Hasler M., De Feo O., Do K. Q., 2008. Acta Psychiatrica Scandinavica, 118 (3) pp. 188-199. Peer-reviewed.
 
Can glutathione deficit be a risk factor in the disconnectivity syndrome
Do Kim Quang, 2008. pp. 29-30 dans Schizophrenia Research, Schizophrenia Research. Peer-reviewed.
 
Glutathione deficit in schizophrenia: strategies to increase glutathione levels in in vitro and in clinical studies
Lavoie S., Steullet P., Murray M., Conus P., Cuenod M., Do K. Q., 2008. pp. A63-A63 dans 6th International Conference on Early Psychosis, Early Intervention in Psychiatry. Peer-reviewed.
 
Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients.
Lavoie S., Murray M.M., Deppen P., Knyazeva M.G., Berk M., Boulat O., Bovet P., Bush A.I., Conus P., Copolov D. et al., 2008. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 33 (9) pp. 2187-99. Peer-reviewed.
 
N-Acetyl Cysteine as a glutathione precursor for schizophrenia-A double-blind, randomized, placebo-controlled trial
Berk Michael, Copolov David, Dean Olivia, Lu Kristy, Jeavons Sue, Schapkaitz Ian, Anderson-Hunt Murray, Judd Fiona, Katz Fiona, Katz Paul et al., 2008. Biological Psychiatry, 64 (5) pp. 361-368. Peer-reviewed.
 
Redox dysregulation and oxidative stress in schizophrenia: genetic and functional anomalies of glutathione synthesis in patients and experimental models involving GABA interneurons and NMDA receptors
Cuenod M., Do K.Q., 2008. p. 38 dans 26th Collegium Internationale Neuro-Psychopharmacologicum Congress (CINP), Munich, GERMANY, JUL 13-17, 2008, International Journal of Neuropsychopharmacology. Peer-reviewed.
 
Gluthatione percursor, N-acetyl-cysteine, modulates mimatch negativity generation in schizophrenia patients
Lavoie S., Murray M., Knyazeva M., Bovet P., Buclin T., Conus P., Deppen P., Meuli R., Solida A., Cuenod M. et al., 2007/03. pp. N/A dans 2007.03.9-10, SSN - NCCR Neuro - SSMS joint meeting, Von Roll Areal, University of Bern, Switzerland. Book of abstract P. 96. Poster I19..
 
The hole-head EEG synchronization landscape in schizophrenia with a new method of S-estimator
Knyazeva M., Jalili M., Do Cuenod K., Bovet P., Cuenod M., Deppen P., Meuli R., Maeder P., Lavoie S., Hasler M. et al., 2007/03. pp. N/A dans SSN - NCCR Neuro - SSMS joint meeting, Von Roll Areal, University of Bern, Switzerland. Book of abstract P.138. PosterJ66.
 
A glutathione precursor, N-acetyl-cysteine, modulates mismatch negativity generation in schizophrenia patients
Lavoie Suzie, Murray Micah M., Knyazeva Maria, Bovet Pierre, Buclin Thierry, Conus Philippe, Deppen Patricia, Meuli Reto, Solida Alessandra, Cuénod Michel et al., 2007. p. 440 dans , Schizophrenia Bulletin. Peer-reviewed.
Dysconnection topography in schizophrenia revealed with state-space analysis of EEG.
Jalili M., Lavoie S., Deppen P., Meuli R., Do K.Q., Cuénod M., Hasler M., De Feo O., Knyazeva M.G., 2007. PLoS ONE, 2 (10) pp. e1059. Peer-reviewed.
 
Glutathione deficit alters dopamine modulation of NMDA-mediated calcium responses via D2 receptormediated signalling pathway: implication of ryanodine receptors and L-type calcium channels
Steullet Pascal, Lavoie Suzie, Guidi Raffaella, Kraftzig R., Cuénod Michel, Do Kim Quang, 2007. p. 316 dans , Schizophrenia Bulletin. Peer-reviewed.
 
Imaging EEG synchronization in schizophrenia patients with S-estimator
Knyazeva Maria G., Jalili M., Do Kim Quang, Bovet Pierre, Cuénod Michel, Deppen Patricia, Meuli Reto, Maeder Philippe, Lavoie Suzie, Vianin Pascal et al., 2007. p. 374 dans , Schizophrenia Bulletin. Peer-reviewed.
 
Impaired glutathione synthesis in schizophrenia: convergent genetic and functional evidence
Gysin R., Kraftsik R., Sandell J., Bovet P., Chappuis C., Conus P., Deppen P., Preisig M., Ruiz V., Steullet P. et al., 2007. Proceedings of the National Academy of Sciences of the United States of America, 104 (42) pp. 16621-16626. Peer-reviewed.
 
Redox dysregulation and oxidative stress in schizophrenia: genetic and fuctional anomalies in glutathione synthesis
Do Kim Quang, Cabungcal Jan Harry, Gysin René, Lavoie Suzie, Steullet Pascal, Tosic Mirjana, Cuénod Michel, 2007. p. 278 dans , Schizophrenia Bulletin. Peer-reviewed.
 
Replenishment of glutathione levels in neurons and astrocytes with compromised GCL activity: relevance to schizophrenia
Lavoie Suzie, Steullet Pascal, Gysin René, Cuénod Michel, Chen Y., Dalton T.P., Do Kim Quang, 2007. p. 318 dans , Schizophrenia Bulletin. Peer-reviewed.
 
TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity.
Kovács K.A., Steullet P., Steinmann M., Do K.Q., Magistretti P.J., Halfon O., Cardinaux J.R., 2007. Proceedings of the National Academy of Sciences of the United States of America, 104 (11) pp. 4700-5. Peer-reviewed.
 
Transitory glutathione deficit during brain development induces cognitive impairment in juvenile and adult rats: relevance to schizophrenia.
Cabungcal J.H., Preissmann D., Delseth C., Cuénod M., Do K.Q., Schenk F., 2007. Neurobiology of disease, 26 (3) pp. 634-45. Peer-reviewed.
 
Allostatic working memory processing in schizophrenia: Human and animal model coherence
Cocchi Laurent, Preissmann Delphine, Do Kim Quang, Vianin Pascal, Schenk Françoise, 2006. pp. 14-15 dans , Neuropsychobiology. Peer-reviewed.
 
Dysregulation of Glutathione Metabolism: A Risk Factor for Schizophrenia
Gysin René, Tosic Curnier Mirjana, Chappuis Céline, Deppen Patricia, Ruiz Viviane, Cuénod Michel, Do Kim Quang, 2006. p. 6 dans , Neuropsychobiology. Peer-reviewed.
 
Genetic vulnerability factor for schizophrenia: association with glutamate cysteine ligase modifier gene and abnormal enzyme activity
Tosic Curnier Mirjana, Ott Jurg, Barral Sandra, Bovet Pierre, Deppen Patricia, Gheorghita F., Matthey Marie-Louise, Parnas Josef, Preisig Martin, Saraga Michael et al., 2006. p. 5 dans , Neuropsychobiology. Peer-reviewed.
 
Glutathione (GSH) Deficit in Schizophrenia: dysfunction of NMDA Receptors and Alteration of Dopamine Modulation of NMDA Responses
Steullet Pascal, Lavoie Suzie, Guidi Raffaella, Do Kim Quang, Cuénod Michel, 2006. p. 3 dans , Neuropsychobiology. Peer-reviewed.
 
Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: relevance to schizophrenia
Cabungcal Jan Harry, Nicolas D., Kraftsik Rudolf, Cuénod Michel, Do Kim Quang, Hornung J.P., 2006. p. 6 dans , Neuropsychobiology. Peer-reviewed.
 
Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: Relevance to schizophrenia.
Cabungcal J.H., Nicolas D., Kraftsik R., Cuénod M., Do K.Q., Hornung J.P., 2006. Neurobiology of disease, 22 (3) pp. 624-37. Peer-reviewed.
 
Glutathione Deficit in Schizophrenia: Replenishment of Glutathione Levels in Neurons and Astrocytes Models
Lavoie Suzie, Steullet Pascal, Cuénod Michel, Do Kim Quang, 2006. p. 6 dans , Neuropsychobiology. Peer-reviewed.
 
Replenishment of glutathione levels in neurons and astrocytes with compromised GCL activity: relevance to schizophrenia
Lavoie Suzie, Steullet Pascal, Gysin René, Cuénod Michel, Chen Y., Dalton T.P., Do Kim Quang, 2006. dans , Abstracts - Society for Neuroscience. Peer-reviewed.
 
Schizophrenia and oxidative stress: glutamate cysteine ligase modifier as a susceptibility gene.
Tosic M., Ott J., Barral S., Bovet P., Deppen P., Gheorghita F., Matthey M.L., Parnas J., Preisig M., Saraga M. et al., 2006. American journal of human genetics, 79 (3) pp. 586-92. Peer-reviewed.
 
Schizophrenia connectivity: correlation between cognitive deficits and reduced thalamo-cortical fibers
Deppen Patricia, Cammoun L., Chappuis Céline, Bovet Pierre, Cuénod Michel, Thiran J.P., Meuli Reto, Do Kim Quang, 2006. p. 11 dans , Neuropsychobiology. Peer-reviewed.
 
Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: Relevance to schizophrenia
Steullet Pascal, Neijt H.C., Cuénod Michel, Do Kim Quang, 2006. Neuroscience, 137 (3) pp. 807-819. Peer-reviewed.
 
Working memory in schizophrenia: dynamic visuo-spatial information processing
Deppen Patricia, Cuénod Michel, Do Kim Quang, Bovet Pierre, Vianin Pascal, 2006. p. 14 dans , Neuropsychobiology. Peer-reviewed.
 
Association of glutathione related genes with the risk of schizophrenia
Tosic Mirjana, Ott Jurg, Barral Sandra, Bovet Pierre, Deppen Patricia, Gheorghita F., Matthey Marie-Louise, Preisig Martin, Saraga Michael, Solida Alessandra et al., 2005. dans , Abstracts - Society for Neuroscience. Peer-reviewed.
 
Dysregulation of glutamate cysteine ligase in schizophrenia
Gysin René, Tosic Mirjana, Chappuis Céline, Deppen Patricia, Ruiz Viviane, Bovet Pierre, Cuénod Michel, Do Kim Quang, 2005. dans , Abstracts - Society for Neuroscience. Peer-reviewed.
 
Gene expression deficit in glutathione synthesis: role in the disconnectivity syndrome of schizophrenia
Do Kim Quang, Tosic Mirjana, Bovet Pierre, Cabungcal Jan Harry, Deppen Patricia, Gheorghita F., Hornung J.P., Preisig Martin, Sagara M., Schenk Françoise et al., 2005. p. 288 dans , Schizophrenia Bulletin. Peer-reviewed.
 
Glutathione deficit during development induces anomalies in anterior cingulate GABA interneurones: relevance to schizophrenia
Cabungcal Jan Harry, Nicolas D., Cuénod Michel, Do Kim Quang, Hornung J.P., 2005. p. 258 dans , Schizophrenia Bulletin. Peer-reviewed.
 
Risk of schizophrenia and the glutathione related genes
Tosic Curnier Mirjana, Ott Jurg, Barral Sandra, Bovet Pierre, Deppen Patricia, Gheorghita F., Matthey M., Preisig Martin, Saraga Michael, Solida Alessandra et al., 2005. p. 137 dans , American journal of medical genetics. Part B, Neuropsychiatric genetics. Peer-reviewed.
 
An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development
Castagné Vincent, Cuénod Michel, Do Kim Quang, 2004. Neuroscience, 123 (4) pp. 821-834. Peer-reviewed.
 
Decrease in brain glutathione (GSH) in schizophrenia: effects of a deficiency in GSH on synaptic transmission and plasticity
Steullet Pascal, Cuénod Michel, Neijt H.C., Do Kim Quang, 2004. p. 124 dans , Schizophrenia Research. Peer-reviewed.
 
Glutamate-induced homocysteic acid release from astrocytes: possible implication in glia-neuron signaling
Benz Beatrix, Grima Gilbert, Do Kim Quang, 2004. Neuroscience, 124 (2) pp. 377-386. Peer-reviewed.
 
Glutathione deficit in schizophrenia: a new vulnerability factor for misconnectivity ?
Do Kim Quang, Bovet Pierre, Cabungcal Jan Harry, Castagné Vincent, Gheorghita F., Hornung J.P., Schenk Françoise, Steullet Pascal, Tosic Mirjana, Cuénod Michel, 2004. p. 118 dans , Schizophrenia Research. Peer-reviewed.
 
Glutathione deficit in schizophrenia: a vulnerability factor for disconnectivity ?
Do Kim Quang, Bovet Pierre, Cabungcal Jan Harry, Castagné Vincent, Gheorghita F., Hornung J.P., Schenk Françoise, Steullet Pascal, Tosic Mirjana, Cuénod Michel, 2004. dans , Abstracts - Society for Neuroscience. Peer-reviewed.
 
Low brain glutathione and ascorbic acid associated with dopamine uptake inhibition during rat's development induce long-term cognitive deficit: relevance to schizophrenia
Castagné Vincent, Rougemont Michael, Cuénod Michel, Do Kim Quang, 2004. Neurobiology of Disease, 15 (1) pp. 93-105. Peer-reviewed.
 
Release of homocysteic acid from rat thalamus following stimulation of somatosensory afferents in vivo: feasibility of glial participation in synaptic transmission.
Do K.Q., Benz B., Binns K.E., Eaton S.A., Salt T.E., 2004. Neuroscience, 124 (2) pp. 387-393. Peer-reviewed.
 
Role of glutathione deficit in the disconnectivity syndrome in schizophrenia: from pathogenetic mechanisms to therapeutic interventions
Do K.Q., Bovet P., Cabungcal J.H., Castagné V., Gheorghita F., Hornung J.P., Schenk F., Steullet P., Tosic M., Cuénod M., 2004. p. 13 dans 6. Drei-Länder-Symposium für Biologische Psychiatrie, European Archives of Psychiatry and Clinical Neuroscience. Peer-reviewed.
 
Schizophrenia patients show reduced expression of the glutathione related genes
Tosic Mirjana, Bovet Pierre, Deppen Patricia, Gheorghita F., Preisig Martin, Saraga Michael, Solida Alessandra, Cuénod Michel, Do Kim Quang, 2004. dans , Abstracts - Society for Neuroscience. Peer-reviewed.
 
Schizophrenia: glutathione deficit as a new vulnerability factor for disconnectivity syndrome
Do Kim Quang, Bovet Pierre, Cuénod Michel, 2004. Schweizer Archiv für Neurologie und Psychiatrie = Archives suisses de neurologie et de psychiatrie, 155 (8) pp. 375-385.
 
Spacial bias deficit in rats with low glutathione during development: an animal behaviour mjodel with relevance to schizophrenia
Cabungcal Jan Harry, Singer D., Hornung J.P., Cuénod Michel, Do Kim Quang, Schenk Françoise, 2004. p. 118 dans , Schizophrenia Research. Peer-reviewed.
 
A rat model with relevance to schizophrenia: low brain glutathione levels during development induce long-term cognitive deficit
Do Kim Quang, Rougemont M., Cuénod Michel, Castagné Vincent, 2003. p. 105 dans , Schizophrenia Research. Peer-reviewed.
Partagez:
Unicentre - CH-1015 Lausanne
Suisse
Tél. +41 21 692 11 11
Swiss University