Bernard Thorens

Publications | Mémoires et thèses

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284 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | ...
2024
 
GLP-1 metabolite GLP-1(9-36) is a systemic inhibitor of mouse and human pancreatic islet glucagon secretion.
Gandasi N.R., Gao R., Kothegala L., Pearce A., Santos C., Acreman S., Basco D., Benrick A., Chibalina M.V., Clark A. et al., 2024/03. Diabetologia, 67 (3) pp. 528-546. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_103D19D01324]
 
Correction to: Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.
Castillo-Armengol J., Marzetta F., Sanchez-Archidona A.R., Fledelius C., Evans M., McNeilly A., McCrimmon R.J., Ibberson M., Thorens B., 2024/02. Diabetologia, 67 (2) p. 403. Peer-reviewed.
[DOI][Pmid][serval:BIB_FEB57D232C9A]
 
Disrupted hypothalamic transcriptomics and proteomics in a mouse model of type 2 diabetes exposed to recurrent hypoglycaemia.
Castillo-Armengol J., Marzetta F., Rodriguez Sanchez-Archidona A., Fledelius C., Evans M., McNeilly A., McCrimmon R.J., Ibberson M., Thorens B., 2024/02. Diabetologia, 67 (2) pp. 371-391. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DAB1C797DF65]
2023
 
The glucose transporter 2 regulates CD8<sup>+</sup> T cell function via environment sensing.
Fu H., Vuononvirta J., Fanti S., Bonacina F., D'Amati A., Wang G., Poobalasingam T., Fankhaenel M., Lucchesi D., Coleby R. et al., 2023/11. Nature metabolism, 5 (11) pp. 1969-1985. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D0F2621B2B52]
 
Hyperglycemia increases SCO-spondin and Wnt5a secretion into the cerebrospinal fluid to regulate ependymal cell beating and glucose sensing.
Nualart F., Cifuentes M., Ramírez E., Martínez F., Barahona M.J., Ferrada L., Saldivia N., Bongarzone E.R., Thorens B., Salazar K., 2023/09. PLoS biology, 21 (9) pp. e3002308. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2C4A3E6F11B7]
 
Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia.
Gaspari S., Labouèbe G., Picard A., Berney X., Rodriguez Sanchez-Archidona A., Thorens B., 2023/08/03. EMBO reports, 24 (8) pp. e57344. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A52AA25ED9E0]
 
Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes.
McNeilly A.D., Gallagher J.R., Evans M.L., de Galan B.E., Pedersen-Bjergaard U., Thorens B., Dinkova-Kostova A.T., Huang J.T., Ashford MLJ, McCrimmon R.J. et al., 2023/07. Diabetologia, 66 (7) pp. 1340-1352. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B75AA47AC9B0]
 
Identification of biomarkers for glycaemic deterioration in type 2 diabetes.
Slieker R.C., Donnelly L.A., Akalestou E., Lopez-Noriega L., Melhem R., Güneş A., Abou Azar F., Efanov A., Georgiadou E., Muniangi-Muhitu H. et al., 2023/05/03. Nature communications, 14 (1) p. 2533. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0BEB8E436325]
Oral metformin transiently lowers post-prandial glucose response by reducing the apical expression of sodium-glucose co-transporter 1 in enterocytes.
Zubiaga L., Briand O., Auger F., Touche V., Hubert T., Thevenet J., Marciniak C., Quenon A., Bonner C., Peschard S. et al., 2023/04/21. iScience, 26 (4) p. 106057. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_809E9916B9DC]
 
A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production.
Gautier-Stein A., Chilloux J., Soty M., Thorens B., Place C., Zitoun C., Duchampt A., Da Costa L., Rajas F., Lamaze C. et al., 2023/04. Molecular metabolism, 70 p. 101700. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AE3E7E2C2F79]
2022
 
Susumu Seino, MD, DMSci (1948–2021): A Pioneer in the Biology of Insulin Secretion
Accili D., Bell GL, Thorens B., 2022/12/01. Diabetes, 71 (12) pp. 2490-2495.
[DOI][WoS][serval:BIB_0EE7FBD61773]
In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist.
Jones B., Burade V., Akalestou E., Manchanda Y., Ramchunder Z., Carrat G., Nguyen-Tu M.S., Marchetti P., Piemonti L., Leclerc I. et al., 2022/11. Diabetes, obesity & metabolism, 24 (11) pp. 2090-2101. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8988E17BEFA0]
GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting.
Barahona M.J., Langlet F., Labouèbe G., Croizier S., Picard A., Thorens B., García-Robles M.A., 2022/10/21. Scientific reports, 12 (1) p. 17717. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2DC7CCA36643]
 
Lipid biosynthesis enzyme Agpat5 in AgRP-neurons is required for insulin-induced hypoglycemia sensing and glucagon secretion.
Strembitska A., Labouèbe G., Picard A., Berney X.P., Tarussio D., Jan M., Thorens B., 2022/09/30. Nature communications, 13 (1) p. 5761. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B0ED46C3DA7C]
Structural and molecular characterization of paraventricular thalamic glucokinase-expressing neuronal circuits in the mouse.
Gaspari S., Quenneville S., Rodriguez Sanchez-Archidona A., Thorens B., Croizier S., 2022/08. The Journal of comparative neurology, 530 (11) pp. 1773-1949. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_299EE8542FB3]
Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion.
Picard A., Berney X., Castillo-Armengol J., Tarussio D., Jan M., Sanchez-Archidona A.R., Croizier S., Thorens B., 2022/07. Molecular metabolism, 61 p. 101479. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1CB3D41BBDD9]
Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse.
Cruciani-Guglielmacci C., Meneyrol K., Denom J., Kassis N., Rachdi L., Makaci F., Migrenne-Li S., Daubigney F., Georgiadou E., Denis R.G. et al., 2022/05/25. Cells, 11 (11) p. 1737. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1F871C8FB2EF]
Opposite physiological and pathological mTORC1-mediated roles of the CB1 receptor in regulating renal tubular function.
Hinden L., Ahmad M., Hamad S., Nemirovski A., Szanda G., Glasmacher S., Kogot-Levin A., Abramovitch R., Thorens B., Gertsch J. et al., 2022/04/04. Nature communications, 13 (1) p. 1783. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_44E381CD6A10]
Neuronal regulation of glucagon secretion and gluconeogenesis.
Thorens B., 2022/04. Journal of diabetes investigation, 13 (4) pp. 599-607. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F099AC71737F]
2021
Plasma triacylglycerols are biomarkers of β-cell function in mice and humans.
Sánchez-Archidona A.R., Cruciani-Guglielmacci C., Roujeau C., Wigger L., Lallement J., Denom J., Barovic M., Kassis N., Mehl F., Weitz J. et al., 2021/12. Molecular metabolism, 54 p. 101355. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F588B3D1D116]
 
Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice.
Rohrbach A., Caron E., Dali R., Brunner M., Pasquettaz R., Kolotuev I., Santoni F., Thorens B., Langlet F., 2021/11. Molecular metabolism, 53 p. 101311. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_569B8719E376]
 
Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice.
Rohrbach A., Caron E., Dali R., Brunner M., Pasquettaz R., Kolotuev I., Santoni F., Thorens B., Langlet F., 2021/11. Molecular metabolism, 53 p. 101311. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FB786377EBF6]
 
Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study.
Slieker R.C., Donnelly L.A., Fitipaldi H., Bouland G.A., Giordano G.N., Åkerlund M., Gerl M.J., Ahlqvist E., Ali A., Dragan I. et al., 2021/11. Diabetes, 70 (11) pp. 2683-2693. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A3ADFE199CED]
 
Glucokinase neurons of the paraventricular nucleus of the thalamus sense glucose and decrease food consumption.
Kessler S., Labouèbe G., Croizier S., Gaspari S., Tarussio D., Thorens B., 2021/10/22. iScience, 24 (10) p. 103122. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6A809E6725D3]
 
Mike Mueckler (1953-2021): the father of the mammalian SLC2 glucose transporter family.
James D.E., Thorens B., 2021/10/01. American journal of physiology. Endocrinology and metabolism, 321 (4) pp. E490-E492. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_95870970FB85]
Détection cérébrale du glucose et homéostasie du glucose
Thorens Bernard, Labouèbe Gwenaël, 2021/09/01. Médecine des Maladies Métaboliques.
[URN][serval:BIB_4DCE16C1F1C5]
 
Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study.
Slieker R.C., Donnelly L.A., Fitipaldi H., Bouland G.A., Giordano G.N., Åkerlund M., Gerl M.J., Ahlqvist E., Ali A., Dragan I. et al., 2021/09. Diabetologia, 64 (9) pp. 1982-1989. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_05148A44E888]
Fgf15 Neurons of the Dorsomedial Hypothalamus Control Glucagon Secretion and Hepatic Gluconeogenesis.
Picard A., Metref S., Tarussio D., Dolci W., Berney X., Croizier S., Labouebe G., Thorens B., 2021/07. Diabetes, 70 (7) pp. 1443-1457. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6BC81E235D09]
 
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes.
Wigger L., Barovic M., Brunner A.D., Marzetta F., Schöniger E., Mehl F., Kipke N., Friedland D., Burdet F., Kessler C. et al., 2021/07. Nature metabolism, 3 (7) pp. 1017-1031. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CE60701C01FB]
 
Cold-induced dishabituation in rodents exposed to recurrent hypoglycaemia.
Vickneson K., Blackburn J., Gallagher J.R., Evans M.L., de Galan B.E., Pedersen-Bjergaard U., Thorens B., McNeilly A.D., McCrimmon R.J., 2021/06. Diabetologia, 64 (6) pp. 1436-1441. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D425FAD2417A]
2020
Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.
Marselli L., Piron A., Suleiman M., Colli M.L., Yi X., Khamis A., Carrat G.R., Rutter G.A., Bugliani M., Giusti L. et al., 2020/12/01. Cell reports, 33 (9) p. 108466. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EA019EC4C301]
 
EphrinB1 modulates glutamatergic inputs into POMC-expressing progenitors and controls glucose homeostasis.
Gervais M., Labouèbe G., Picard A., Thorens B., Croizier S., 2020/11. PLoS biology, 18 (11) pp. e3000680. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_342F83D79CC2]
Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation.
Quenneville S., Labouèbe G., Basco D., Metref S., Viollet B., Foretz M., Thorens B., 2020/11. Diabetes, 69 (11) pp. 2253-2266. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8D8A4D281085]
 
Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.
Castillo-Armengol J., Barquissau V., Geller S., Ji H., Severi I., Venema W., Fenandez E.A., Moret C., Huber K., Leal-Esteban L.C. et al., 2020/09/03. EMBO reports, 21 (9) pp. e49807. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BA842E7BA291]
The Constitutive Lack of α7 Nicotinic Receptor Leads to Metabolic Disorders in Mouse.
Gausserès B., Liu J., Foppen E., Tourrel-Cuzin C., Rodriguez Sanchez-Archidona A., Delangre E., Cruciani-Guglielmacci C., Pons S., Maskos U., Thorens B. et al., 2020/07/16. Biomolecules, 10 (7) p. 1057. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1E982C7D4533]
 
A genetic screen identifies Crat as a regulator of pancreatic beta-cell insulin secretion.
Berdous D., Berney X., Sanchez-Archidona A.R., Jan M., Roujeau C., Lopez-Mejia I.C., Mynatt R., Thorens B., 2020/07. Molecular metabolism, 37 p. 100993. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E7C44B7C6874]
Klf6 protects β-cells against insulin resistance-induced dedifferentiation.
Dumayne C., Tarussio D., Sanchez-Archidona A.R., Picard A., Basco D., Berney X.P., Ibberson M., Thorens B., 2020/05. Molecular metabolism, 35 p. 100958. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_48A38BFBF2D1]
 
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C., Wang P., Karakose E., Manning Fox J.E., González B.J., Liu H., Wilson J., Swartz E., Berrouet C., Li Y. et al., 2020/02/12. Science translational medicine, 12 (530). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4E3C5CE86DB9]
2019
Glucose transporter 2 mediates the hypoglycemia-induced increase in cerebral blood flow.
Lei H., Preitner F., Labouèbe G., Gruetter R., Thorens B., 2019/09. Journal of cerebral blood flow and metabolism, 39 (9) pp. 1725-1736. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FAB7A3D6BC78]
Use of preclinical models to identify markers of type 2 diabetes susceptibility and novel regulators of insulin secretion - A step towards precision medicine.
Thorens B., Rodriguez A., Cruciani-Guglielmacci C., Wigger L., Ibberson M., Magnan C., 2019/09. Molecular metabolism, 27S pp. S147-S154. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6163E1B2777E]
Fostering improved human islet research: a European perspective.
Marchetti P., Schulte A.M., Marselli L., Schoniger E., Bugliani M., Kramer W., Overbergh L., Ullrich S., Gloyn A.L., Ibberson M. et al., 2019/08. Diabetologia, 62 (8) pp. 1514-1516. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4EAABE7C8EB6]
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes.
Khamis A., Canouil M., Siddiq A., Crouch H., Falchi M., Bulow M.V., Ehehalt F., Marselli L., Distler M., Richter D. et al., 2019/06. Molecular metabolism, 24 pp. 98-107. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5EA2C0408F1C]
 
Targeting the Brain to Cure Type 2 Diabetes.
Thorens B., 2019/03. Diabetes, 68 (3) pp. 476-478. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1E341707A95B]
Profound Perturbation of the Metabolome in Obesity Is Associated with Health Risk.
Cirulli E.T., Guo L., Leon Swisher C., Shah N., Huang L., Napier L.A., Kirkness E.F., Spector T.D., Caskey C.T., Thorens B. et al., 2019/02/05. Cell metabolism, 29 (2) pp. 488-500.e2. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D194EFF94799]
2018
SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney.
Auberson M., Stadelmann S., Stoudmann C., Seuwen K., Koesters R., Thorens B., Bonny O., 2018/12. Pflugers Archiv, 470 (12) pp. 1739-1751. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_789F1130AFFD]
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes.
Solimena M., Schulte A.M., Marselli L., Ehehalt F., Richter D., Kleeberg M., Mziaut H., Knoch K.P., Parnis J., Bugliani M. et al., 2018/03. Diabetologia, 61 (3) pp. 641-657. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B55984D6D1A]
α-cell glucokinase suppresses glucose-regulated glucagon secretion.
Basco D., Zhang Q., Salehi A., Tarasov A., Dolci W., Herrera P., Spiliotis I., Berney X., Tarussio D., Rorsman P. et al., 2018/02/07. Nature communications, 9 (1) p. 546. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C69CB1A44E4C]
 
GLUT2-Expressing Neurons as Glucose Sensors in the Brain: Electrophysiological Analysis.
Labouèbe G., Thorens B., Lamy C., 2018. Methods in molecular biology, 1713 pp. 255-267. Peer-reviewed.
[DOI][Pmid][serval:BIB_E8138BB17B01]
 
Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.
Bellini L., Campana M., Rouch C., Chacinska M., Bugliani M., Meneyrol K., Hainault I., Lenoir V., Denom J., Véret J. et al., 2018. Diabetologia, 61 (8) pp. 1780-1793. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_09B101397D37]
2017
 
Carbohydrates and insulin resistance in clinical nutrition: Recommendations from the ESPEN expert group.
Barazzoni R., Deutz NEP, Biolo G., Bischoff S., Boirie Y., Cederholm T., Cuerda C., Delzenne N., Leon Sanz M., Ljungqvist O. et al., 2017/04. Clinical nutrition, 36 (2) pp. 355-363. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CA0F054B95AB]
Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for <i>Elovl2</i> in glucose-induced insulin secretion.
Cruciani-Guglielmacci C., Bellini L., Denom J., Oshima M., Fernandez N., Normandie-Levi P., Berney X.P., Kassis N., Rouch C., Dairou J. et al., 2017/04. Molecular metabolism, 6 (4) pp. 340-351. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0B44EFB14BA9]
Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.
Wigger L., Cruciani-Guglielmacci C., Nicolas A., Denom J., Fernandez N., Fumeron F., Marques-Vidal P., Ktorza A., Kramer W., Schulte A. et al., 2017/02/28. Cell reports, 18 (9) pp. 2269-2279. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_78CB07C09AAA]
 
Alain Ktorza, PhD in Memoriam
Thorens B., Accili D., Ahrén B., Boitard C., Seino S., Cerasi E., 2017. Diabetes, Obesity & Metabolism, 19 (Suppl 1) p. 3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_28B1BF3920FA]
 
Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation.
Dror E., Dalmas E., Meier D.T., Wueest S., Thévenet J., Thienel C., Timper K., Nordmann T.M., Traub S., Schulze F. et al., 2017. Nature Immunology, 18 (3) pp. 283-292. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C7DF25C96E75]
2016
A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion.
Picard A., Soyer J., Berney X., Tarussio D., Quenneville S., Jan M., Grouzmann E., Burdet F., Ibberson M., Thorens B., 2016/11/08. Cell reports, 17 (7) pp. 1795-1806. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F3E314BF94F2]
 
Sex-Specific Control of Fat Mass and Counterregulation by Hypothalamic Glucokinase.
Steinbusch L.K., Picard A., Bonnet M.S., Basco D., Labouèbe G., Thorens B., 2016/10. Diabetes, 65 (10) pp. 2920-2931. Peer-reviewed.
[DOI][Pmid][serval:BIB_A295C7CD011C]
 
Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice.
Sala-Rabanal M., Hirayama B.A., Ghezzi C., Liu J., Huang S.C., Kepe V., Koepsell H., Yu A., Powell D.R., Thorens B. et al., 2016/08/01. The Journal of physiology, 594 (15) pp. 4425-4438. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D45FD8D921C6]
 
The Drosophila TNF Eiger Is an Adipokine that Acts on Insulin-Producing Cells to Mediate Nutrient Response.
Agrawal N., Delanoue R., Mauri A., Basco D., Pasco M., Thorens B., Léopold P., 2016/04/12. Cell metabolism, 23 (4) pp. 675-684.
[DOI][Pmid][serval:BIB_7DAD4070486A]
Glucose-responsive neurons of the paraventricular thalamus control sucrose-seeking behavior.
Labouèbe G., Boutrel B., Tarussio D., Thorens B., 2016. Nature Neuroscience, 19 (8) pp. 999-1002.
[URN][DOI][WoS][Pmid][serval:BIB_A148E50B94B8]
Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction.
Duszka K., Picard A., Ellero-Simatos S., Chen J., Defernez M., Paramalingam E., Pigram A., Vanoaica L., Canlet C., Parini P. et al., 2016. Scientific Reports, 6 p. 36937. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4F2384AD45B8]
 
Sorcin links pancreatic β cell lipotoxicity to ER Ca2+ stores.
Marmugi A., Parnis J., Chen X., Carmichael L., Hardy J., Mannan N., Marchetti P., Piemonti L., Bosco D., Johnson P. et al., 2016. Diabetes, 65 (4) pp. 1009-1021.
[DOI][WoS][Pmid][serval:BIB_FD358A981FEB]
2015
 
Autocrine Action of IGF2 Regulates Adult β-Cell Mass and Function.
Modi H., Jacovetti C., Tarussio D., Metref S., Madsen O.D., Zhang F.P., Rantakari P., Poutanen M., Nef S., Gorman T. et al., 2015. Diabetes, 64 (12) pp. 4148-4157. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1ECFC1603DDF]
 
Brain glucose sensing in homeostatic and hedonic regulation.
Steinbusch L., Labouèbe G., Thorens B., 2015. Trends In Endocrinology and Metabolism: Tem, 26 (9) pp. 455-466.
[DOI][WoS][Pmid][serval:BIB_FF757947DDA9]
 
Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
Marquard J., Otter S., Welters A., Stirban A., Fischer A., Eglinger J., Herebian D., Kletke O., Klemen M.S., Stožer A. et al., 2015. Nature Medicine, 21 (4) pp. 363-372.
[DOI][WoS][Pmid][serval:BIB_76486F09E4DC]
Clic4, a novel protein that sensitizes β-cells to apoptosis.
Patel D., Ythier D., Brozzi F., Eizirik D.L., Thorens B., 2015. Molecular Metabolism, 4 (4) pp. 253-264.
[URN][DOI][WoS][Pmid][serval:BIB_F1F8D030E49F]
 
Double incretin receptor knock-out (DIRKO) mice present with alterations of trabecular and cortical micromorphology and bone strength.
Mieczkowska A., Mansur S., Bouvard B., Flatt P.R., Thorens B., Irwin N., Chappard D., Mabilleau G., 2015. Osteoporosis International, 26 (1) pp. 209-218.
[DOI][WoS][Pmid][serval:BIB_E02F75358177]
 
GLUT2, glucose sensing and glucose homeostasis.
Thorens B., 2015. Diabetologia, 58 (2) pp. 221-232.
[DOI][WoS][Pmid][serval:BIB_2A2C9C393369]
Ins1 (Cre) knock-in mice for beta cell-specific gene recombination.
Thorens B., Tarussio D., Maestro M.A., Rovira M., Heikkilä E., Ferrer J., 2015. Diabetologia, 58 (3) pp. 558-565.
[URN][DOI][WoS][Pmid][serval:BIB_5988E610912C]
 
No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse.
Preitner F., Pimentel A., Metref S., Berthonneche C., Sarre A., Moret C., Rotman S., Centeno G., Firsov D., Thorens B., 2015. Kidney International, 87 (5) pp. 940-947.
[DOI][WoS][Pmid][serval:BIB_ADDFD3771EC7]
Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass.
Mitchell R.K., Mondragon A., Chen L., Mcginty J.A., French P.M., Ferrer J., Thorens B., Hodson D.J., Rutter G.A., Da Silva Xavier G., 2015. Human Molecular Genetics, 24 (5) pp. 1390-1399.
[URN][DOI][WoS][Pmid][serval:BIB_1F4851B77D5E]
 
The Islet and Metabolism Keep Time.
Thorens B., Accili D., Ahrén B., Cerasi E., Seino S., Boitard C., 2015. Diabetes, Obesity and Metabolism, 17 Suppl 1 pp. 3-5. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6EB9751BDCCD]
Type 2 Diabetes, SGLT2 Inhibitors, and Glucose Secretion.
Hattersley A.T., Thorens B., 2015. New England Journal of Medicine, 373 (10) pp. 974-976. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DA645CAAB37A]
2014
Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development.
Winnik S., Gaul D.S., Preitner F., Lohmann C., Weber J., Miranda M.X., Liu Y., van Tits L.J., Mateos J.M., Brokopp C.E. et al., 2014. Basic Research in Cardiology, 109 (1) p. 399.
[URN][DOI][WoS][Pmid][serval:BIB_4C59E5F3E282]
Gluco-incretins regulate beta-cell glucose competence by epigenetic silencing of Fxyd3 expression.
Vallois D., Niederhäuser G., Ibberson M., Nagaray V., Marselli L., Marchetti P., Chatton J.Y., Thorens B., 2014. PLoS One, 9 (7) pp. e103277.
[URN][DOI][WoS][Pmid][serval:BIB_6DFE810B8150]
 
Glutamine Stimulates Biosynthesis and Secretion of Insulin-like Growth Factor 2 (IGF2), an Autocrine Regulator of Beta Cell Mass and Function.
Modi H., Cornu M., Thorens B., 2014. Journal of Biological Chemistry, 289 (46) pp. 31972-31982.
[DOI][WoS][Pmid][serval:BIB_7A4FD832AC4E]
Hypoglycemia-activated GLUT2 neurons of the nucleus tractus solitarius stimulate vagal activity and glucagon secretion.
Lamy C.M., Sanno H., Labouèbe G., Picard A., Magnan C., Chatton J.Y., Thorens B., 2014. Cell Metabolism, 19 (3) pp. 527-538. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_15A261115513]
Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy.
Moffett R.C., Vasu S., Thorens B., Drucker D.J., Flatt P.R., 2014. PLoS One, 9 (6) pp. e96863.
[URN][DOI][WoS][Pmid][serval:BIB_3C41D2B7D38E]
LKB1 and AMPK differentially regulate pancreatic β-cell identity.
Kone M., Pullen T.J., Sun G., Ibberson M., Martinez-Sanchez A., Sayers S., Nguyen-Tu M.S., Kantor C., Swisa A., Dor Y. et al., 2014. FASEB Journal, 28 (11) pp. 4972-4985.
[URN][DOI][WoS][Pmid][serval:BIB_8F808B5B27DA]
 
Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis.
Tarussio D., Metref S., Seyer P., Mounien L., Vallois D., Magnan C., Foretz M., Thorens B., 2014. Journal of Clinical Investigation, 124 (1) pp. 413-424.
[DOI][WoS][Pmid][serval:BIB_C99AAAC646C7]
 
Neural regulation of pancreatic islet cell mass and function.
Thorens B., 2014. Diabetes, Obesity and Metabolism, 16 Suppl 1 pp. 87-95.
[DOI][WoS][Pmid][serval:BIB_9CA51BF594BB]
Role of Endogenous GLP-1 and GIP in Beta Cell Compensatory Responses to Insulin Resistance and Cellular Stress.
Vasu S., Moffett R.C., Thorens B., Flatt P.R., 2014. PLoS One, 9 (6) pp. e101005.
[URN][DOI][WoS][Pmid][serval:BIB_5305E7426977]
 
The mind and the belly: a glance at how the nervous system directs metabolism.
Accili D., Ahrén B., Boitard C., Seino S., Thorens B., Cerasi E., 2014. Diabetes, Obesity and Metabolism, 16 Suppl 1 pp. 1-3.
[DOI][WoS][Pmid][serval:BIB_05D8A13D71BA]
The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing.
Röder P.V., Geillinger K.E., Zietek T.S., Thorens B., Koepsell H., Daniel H., 2014. PLoS One, 9 (2) pp. e89977.
[URN][DOI][WoS][Pmid][serval:BIB_7C899152E1B3]
2013
 
Glucose-dependent insulinotropic polypeptide receptor deficiency leads to modifications of trabecular bone volume and quality in mice.
Gaudin-Audrain C., Irwin N., Mansur S., Flatt P.R., Thorens B., Baslé M., Chappard D., Mabilleau G., 2013. Bone, 53 (1) pp. 221-230.
[DOI][WoS][Pmid][serval:BIB_001D7D0300C2]
Hepatic glucose sensing is required to preserve β cell glucose competence.
Seyer P., Vallois D., Poitry-Yamate C., Schütz F., Metref S., Tarussio D., Maechler P., Staels B., Lanz B., Grueter R. et al., 2013. Journal of Clinical Investigation, 123 (4) pp. 1662-1676.
[URN][DOI][WoS][Pmid][serval:BIB_FD22C2D96632]
 
Incretins: what is known, new and controversial in 2013?
Burcelin R., Thorens B., European Club for the study of GLP-1 (EuCSGLP-1), 2013. Diabetes and Metabolism, 39 (2) pp. 89-93.
[DOI][WoS][Pmid][serval:BIB_332AD78EFBA4]
Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 mice
Lengacher S., Nehiri-Sitayeb T., Steiner N., Carneiro L., Favrod C., Preitner F., Thorens B., Stehle J.C., Dix L., Pralong F. et al., 2013. PLoS One, 8 (12) pp. e82505.
[URN][DOI][WoS][Pmid][serval:BIB_7C2648899BDB]
Shifting the paradigm of islet inflammation-good guy or bad guy?
Ahrén B., Accili D., Boitard C., Cerasi E., Thorens B., Seino S., 2013. Diabetes, Obesity and Metabolism, 15 Suppl 3 pp. 4-9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4DCB052B4B34]
 
Sodium/hydrogen exchanger NHA2 is critical for insulin secretion in β-cells.
Deisl C., Simonin A., Anderegg M., Albano G., Kovacs G., Ackermann D., Moch H., Dolci W., Thorens B., A Hediger M. et al., 2013. Proceedings of the National Academy of Sciences of the United States of America, 110 (24) pp. 10004-10009. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D523B7B158A1]
The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids.
Ding J., Loizides-Mangold U., Rando G., Zoete V., Michielin O., Reddy J.K., Wahli W., Riezman H., Thorens B., 2013. Cell Reports, 5 (1) pp. 248-258.
[URN][DOI][WoS][Pmid][serval:BIB_32435212F771]
 
The required beta cell research for improving treatment of type 2 diabetes.
Thorens B., 2013. Journal of Internal Medicine, 274 (3) pp. 203-214.
[DOI][WoS][Pmid][serval:BIB_4A66DC9B3E91]
The SLC2 (GLUT) family of membrane transporters.
Mueckler M., Thorens B., 2013. Molecular Aspects of Medicine, 34 (2-3) pp. 121-138. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A2607C275E16]
 
Urate-induced acute renal failure and chronic inflammation in liver-specific Glut9 knockout mice.
Preitner F., Laverriere-Loss A., Metref S., Da Costa A., Moret C., Rotman S., Bazin D., Daudon M., Sandt C., Dessombz A. et al., 2013. American Journal of Physiology. Renal Physiology, 305 (5) pp. F786-F795.
[DOI][WoS][Pmid][serval:BIB_F25B127A38C2]
2012
 
Fanconi-Bickel syndrome and autosomal recessive proximal tubulopathy with hypercalciuria (ARPTH) are allelic variants caused by GLUT2 mutations.
Mannstadt M., Magen D., Segawa H., Stanley T., Sharma A., Sasaki S., Bergwitz C., Mounien L., Boepple P., Thorens B. et al., 2012. Journal of Clinical Endocrinology and Metabolism, 97 (10) pp. E1978-E1986.
[DOI][WoS][Pmid][serval:BIB_79FF147750F9]
MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity.
Jacovetti C., Abderrahmani A., Parnaud G., Jonas J.C., Peyot M.L., Cornu M., Laybutt R., Meugnier E., Rome S., Thorens B. et al., 2012. Journal of Clinical Investigation, 122 (10) pp. 3541-3551. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3EFD603B48DE]
Plac8 is required for white adipocyte differentiation in vitro and cell number control in vivo.
Jimenez-Preitner M., Berney X., Thorens B., 2012. PLoS One, 7 (11) pp. e48767.
[URN][DOI][WoS][Pmid][serval:BIB_EAD35B24DA6A]
 
PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice.
Iglesias J., Barg S., Vallois D., Lahiri S., Roger C., Yessoufou A., Pradevand S., McDonald A., Bonal C., Reimann F. et al., 2012. Journal of Clinical Investigation, 122 (11) pp. 4105-4117.
[DOI][WoS][Pmid][serval:BIB_185C03FE1024]
 
Sensing of glucose in the brain.
Thorens B., 2012. pp. 277-294 dans Joost H.G. (eds.) Appetite control, Springer-Verlag.
[DOI][Pmid][serval:BIB_2D4773FC7904]
 
The hyperstimulated β-cell: prelude to diabetes?
Boitard C., Accili D., Ahrén B., Cerasi E., Seino S., Thorens B., 2012. Diabetes, Obesity and Metabolism, 14 Suppl 3 pp. iv-viii.
[DOI][WoS][Pmid][serval:BIB_B67C9A5A929C]
2011
Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease.
Banasik K., Justesen J.M., Hornbak M., Krarup N.T., Gjesing A.P., Sandholt C.H., Jensen T.S., Grarup N., Andersson A., Jørgensen T. et al., 2011. PLoS One, 6 (1) pp. e16542.
[URN][DOI][WoS][Pmid][serval:BIB_A59C7FE62C49]
 
Brain glucose sensing and neural regulation of insulin and glucagon secretion.
Thorens B., 2011. Diabetes, Obesity and Metabolism, 13 (Suppl 1) pp. 82-88.
[WoS][Pmid][serval:BIB_F5B70378AC20]
 
Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis.
Faivre E., Gault V.A., Thorens B., Hölscher C., 2011. Journal of Neurophysiology, 105 (4) pp. 1574-1580.
[DOI][WoS][Pmid][serval:BIB_CBB8AAFE016B]
In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.
Hu He K.H., Lorenzo P.I., Brun T., Jimenez Moreno C.M., Aeberhard D., Vallejo Ortega J., Cornu M., Thorel F., Gjinovci A., Thorens B. et al., 2011. Diabetes, 60 (6) pp. 1705-1715.
[URN][DOI][WoS][Pmid][serval:BIB_0D2579782668]
Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice.
Thorel F., Damond N., Chera S., Wiederkehr A., Thorens B., Meda P., Wollheim C.B., Herrera P.L., 2011. Diabetes, 60 (11) pp. 2872-2882.
[URN][DOI][WoS][Pmid][serval:BIB_16B62B557AAA]
 
Of fat, β cells, and diabetes.
Thorens B., 2011. Cell Metabolism, 14 (4) pp. 439-440.
[DOI][WoS][Pmid][serval:BIB_420709167259]
Oxidative phosphorylation flexibility in the liver of mice resistant to high-fat diet-induced hepatic steatosis.
Poussin C., Ibberson M., Hall D., Ding J., Soto J., Abel E.D., Thorens B., 2011. Diabetes, 60 (9) pp. 2216-2224.
[URN][DOI][WoS][Pmid][serval:BIB_90E2A4ED2946]
 
PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.
Becattini B., Marone R., Zani F., Arsenijevic D., Seydoux J., Montani J.P., Dulloo A.G., Thorens B., Preitner F., Wymann M.P. et al., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (42) pp. E854-E863.
[DOI][WoS][Pmid][serval:BIB_F18D7780E975]
 
Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.
Jimenez-Preitner M., Berney X., Uldry M., Vitali A., Cinti S., Ledford J.G., Thorens B., 2011. Cell Metabolism, 14 (5) pp. 658-670.
[DOI][WoS][Pmid][serval:BIB_9E6C78808E97]
2010
 
Central control of glucose homeostasis: the brain--endocrine pancreas axis.
Thorens B., 2010. Diabetes and Metabolism, 36 (Suppl 3) pp. S45-S49.
[DOI][WoS][Pmid][serval:BIB_E07505102FD3]
 
Central glucose sensing and the control of energy homeostasis
Thorens B., 2010. pp. S222 dans 14th International Congress of Endocrinology, Endocrine Journal. Peer-reviewed.
[WoS][serval:BIB_D8EA2E7744DA]
EuroDia: a beta-cell gene expression resource.
Liechti R., Csárdi G., Bergmann S., Schütz F., Sengstag T., Boj S.F., Servitja J.M., Ferrer J., Van Lommel L., Schuit F. et al., 2010. Database, 2010 pp. baq024.
[URN][DOI][Pmid][serval:BIB_0D9E4ED81B05]
 
Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression.
Cornu M., Modi H., Kawamori D., Kulkarni R.N., Joffraud M., Thorens B., 2010. Journal of Biological Chemistry, 285 (14) pp. 10538-10545. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F6D8AE70F677]
 
Glucose transporters in the 21st Century.
Thorens B., Mueckler M.M., 2010. American Journal of Physiology. Endocrinology and Metabolism, 298 pp. 141-5.
[DOI][WoS][Pmid][serval:BIB_982480052E61]
 
Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons.
Mounien L., Marty N., Tarussio D., Metref S., Genoux D., Preitner F., Foretz M., Thorens B., 2010. FASEB Journal, 24 (6) pp. 1747-1758. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F27D6E977007]
 
Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14.1T.
Lei H., Poitry-Yamate C., Preitner F., Thorens B., Gruetter R., 2010. NMR in Biomedicine, 23 (6) pp. 578-583.
[DOI][WoS][Pmid][serval:BIB_57A93519A4EC]
 
Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state.
Hall D., Poussin C., Velagapudi V.R., Empsen C., Joffraud M., Beckmann J.S., Geerts A.E., Ravussin Y., Ibberson M., Oresic M. et al., 2010. Journal of Biological Chemistry, 285 (40) pp. 31011-31023.
[DOI][WoS][Pmid][serval:BIB_5C7339688FC7]
 
Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
Zhou R., Tardivel A., Thorens B., Choi I., Tschopp J., 2010. Nature Immunology, 11 (2) pp. 136-140. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E05AA44F8170]
 
Uric acid transport and disease.
So A., Thorens B., 2010. Journal of Clinical Investigation, 120 (6) pp. 1791-1799.
[DOI][WoS][Pmid][serval:BIB_74F7918F742F]
2009
Expression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes.
Yang J.Y., Walicki J., Jaccard E., Dubuis G., Bulat N., Hornung J.P., Thorens B., Widmann C., 2009. Diabetes, 58 (11) pp. 2596-2606. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9B124E90768D]
 
GLP-1 protects beta-cells against apoptosis by enhancing the activity of an IGF-2/IGF-1 receptor autocrine loop
Cornu M, Thorens B, 2009. Islets, 1 (3) pp. 280-282. Peer-reviewed.
[DOI][WoS][serval:BIB_3E5801696B4F]
Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop.
Cornu M., Yang J.Y., Jaccard E., Poussin C., Widmann C., Thorens B., 2009. Diabetes, 58 (8) pp. 1816-1825. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_67E118FEC494]
 
Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth.
Buhren B.A., Gasis M., Thorens B., Müller H.W., Bosse F., 2009. Journal of Neuroscience Research, 87 (8) pp. 1858-1870.
[DOI][WoS][Pmid][serval:BIB_4A9CD880C6FC]
 
Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy.
Preitner F., Bonny O., Laverrière A., Rotman S., Firsov D., Da Costa A., Metref S., Thorens B., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (36) pp. 15501-15506.
[DOI][WoS][Pmid][serval:BIB_1EC881C9D168]
 
Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells.
Pétremand J., Bulat N., Butty A.C., Poussin C., Rütti S., Au K., Ghosh S., Mooser V., Thorens B., Yang J.Y. et al., 2009. Molecular Endocrinology, 23 (10) pp. 1572-1586. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A437670219D3]
 
Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice.
Isken F., Weickert M.O., Tschöp M.H., Nogueiras R., Möhlig M., Abdelrahman A., Klaus S., Thorens B., Pfeiffer A.F., 2009. Diabetologia, 52 (10) pp. 2159-2168.
[DOI][WoS][Pmid][serval:BIB_28F7A3AC9581]
 
Mouse GLUT9: evidences for a urate uniporter.
Bibert S., Hess S.K., Firsov D., Thorens B., Geering K., Horisberger J.D., Bonny O., 2009. American Journal of Physiology. Renal Physiology, 297 (3) pp. F612-F619. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AE08062CF747]
 
Regulation of adaptive behaviour during fasting by hypothalamic Foxa2.
Silva J.P., von Meyenn F., Howell J., Thorens B., Wolfrum C., Stoffel M., 2009. Nature, 462 (7273) pp. 646-650. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_166ACA9F6A19]
2008
 
Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice
Minehira K., Young S. G., Villanueva C. J., Yetukuri L., Oresic M., Hellerstein M. K., Farese, R. V., Jr. , Horton J. D., Preitner F., Thorens B. et al., 2008. Journal of Lipid Research, 49 (9) pp. 2038-2044. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_07B785837DC7]
 
Deficiency of glucose-dependent insulinotropic polypeptide receptor prevents ovariectomy-induced obesity in mice.
Isken F., Pfeiffer A.F., Nogueiras R., Osterhoff M.A., Ristow M., Thorens B., Tschöp M.H., Weickert M.O., 2008. American journal of physiology. Endocrinology and metabolism, 295 (2) pp. E350-5. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_97909F9D8846]
Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice.
Poussin C., Hall D., Minehira K., Galzin A.M., Tarussio D., Thorens B., 2008. PLoS ONE, 3 (10) pp. e3385. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ED5FF5045C10]
 
Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.
Ferdaoussi M., Abdelli S., Yang J.Y., Cornu M., Niederhauser G., Favre D., Widmann C., Regazzi R., Thorens B., Waeber G. et al., 2008. Diabetes, 57 (5) pp. 1205-1215. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E0C5570050E9]
 
Glucose sensing and the pathogenesis of obesity and type 2 diabetes.
Thorens B., 2008. International Journal of Obesity, 32 Suppl 6 pp. S62-S71.
[DOI][WoS][Pmid][serval:BIB_9135C1738C25]
 
High density lipoproteins protect pancreatic beta cells by targeting 4E-BP1 : 512
Petremand J., Butty A.C., Yang J.Y., Natasa B., Poussin C., Thorens B., Waeber G., Widmann C., 2008. pp. S210 dans Minutes of the 43rd General Assembly of the European Association for the Study of Diabetes, Diabetologia. Peer-reviewed.
[WoS][serval:BIB_BB837FD67235]
 
Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14.
Klinger S., Poussin C., Debril M.B., Dolci W., Halban P.A., Thorens B., 2008. Diabetes, 57 (3) pp. 584-93. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C118D8F1206E]
 
Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice.
Troy S., Soty M., Ribeiro L., Laval L., Migrenne S., Fioramonti X., Pillot B., Fauveau V., Aubert R., Viollet B. et al., 2008. Cell Metabolism, 8 (3) pp. 201-211. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5363474544E9]
 
Molecular biology of gluco-incretin function
Klinger S., Thorens B., 2008. pp. 315-334 dans Seino S., Bell G. I. (eds.) Pancreatic Beta Cell in Health and Disease, Springer.
[serval:BIB_99C5A680EB5D]
 
Mécanismes moléculaires de la fonction anti-apoptotique des HDLs sur la cellule béta pancréatique : 4E-BP1 comme potentielle cible thérapeutique. [Molecular mechanisms of anti-apoptotic function of HDLs on pancreatic beta cells : 4E-BP1 as a potential therapeutic target]
Petremand J., Butty A.C., Yang J.Y., Bulat N., Poussin C., Thorens B., Widmann C., Waeber G., 2008. pp. A23 dans Alfediam 2008, Congrès Annuel de l'Association de Langue Française pour l'Etude du Diabète et des Maladies Métaboiques, Diabetes and Metabolism. Peer-reviewed.
[DOI][WoS][serval:BIB_4F6B2C9687AB]
 
PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.
Zehetner J., Danzer C., Collins S., Eckhardt K., Gerber P.A., Ballschmieter P., Galvanovskis J., Shimomura K., Ashcroft F.M., Thorens B. et al., 2008. Genes and Development, 22 (22) pp. 3135-3146. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FDB216F14E86]
2007
 
Development and preclinical assessment of a bioartificial pancreas.
Thorens B., 2007/03/02. Swiss medical weekly, 137 (Suppl 155) pp. 68S-71S. Peer-reviewed.
[Pmid][serval:BIB_04BDC79A519E]
 
Brain glucose sensing, counterregulation, and energy homeostasis.
Marty N., Dallaporta M., Thorens B., 2007. Physiology, 22 pp. 241-251.
[DOI][WoS][Pmid][serval:BIB_B8E79DA030F3]
 
Expression of the gene encoding the high-Km glucose transporter 2 by the early postimplantation mouse embryo is essential for neural tube defects associated with diabetic embryopathy.
Li R., Thorens B., Loeken M.R., 2007. Diabetologia, 50 (3) pp. 682-689. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_21E6655D5012]
 
GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion.
Cani P.D., Holst J.J., Drucker D.J., Delzenne N.M., Thorens B., Burcelin R., Knauf C., 2007. Molecular and Cellular Endocrinology, 276 (1-2) pp. 18-23. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_03E134BDD2A7]
2006
 
A missing sugar prevents glucose entry: a new twist on insulin secretion.
Thorens B., 2006. Cell Metabolism, 3 (1) pp. 3-5. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_58DB7D37AA11]
A toggle for type 2 diabetes?
Thorens B., 2006. New England Journal of Medicine, 354 (15) pp. 1636-1638.
[URN][DOI][WoS][Pmid][serval:BIB_58E76B1471E6]
 
Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding.
Bady I., Marty N., Dallaporta M., Emery M., Gyger J., Tarussio D., Foretz M., Thorens B., 2006. Diabetes, 55 (4) pp. 988-995. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_58B1E0A07305]
 
GLUT8 is dispensable for embryonic development but influences hippocampal neurogenesis and heart function.
Membrez M., Hummler E., Beermann F., Haefliger J.A., Savioz R., Pedrazzini T., Thorens B., 2006. Molecular and Cellular Biology, 26 (11) pp. 4268-4276. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_762B2B505DC8]
 
L'axe entéro-insulaire: rôle de l'intestin et régulation glycémique
Thorens B., 2006. Journées annuelles de diabétologie de l'Hôtel-Dieu pp. 67-73.
[Pmid][serval:BIB_3B10E99E3EA0]
 
Maintenance of hepatic nuclear factor 6 in postnatal islets impairs terminal differentiation and function of beta-cells.
Tweedie E., Artner I., Crawford L., Poffenberger G., Thorens B., Stein R., Powers A.C., Gannon M., 2006. Diabetes, 55 (12) pp. 3264-3270. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_17F1B0E4FB6D]
 
Peroxisome proliferator-activated receptor-alpha-null mice have increased white adipose tissue glucose utilization, GLUT4, and fat mass: Role in liver and brain.
Knauf C., Rieusset J., Foretz M., Cani P.D., Uldry M., Hosokawa M., Martinez E., Bringart M., Waget A., Kersten S. et al., 2006. Endocrinology, 147 (9) pp. 4067-4078. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4BF6D6D4BC30]
 
Tetracycline-regulated expression of VEGF-A in beta cells induces angiogenesis: improvement of engraftment following transplantation.
Mathe Z., Dupraz P., Rinsch C., Thorens B., Bosco D., Zbinden M., Morel P., Berney T., Pepper M.S., 2006. Cell Transplantation, 15 (7) pp. 621-636. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_76B961622F68]
2005
 
Expression of an uncleavable N-terminal RasGAP fragment in insulin-secreting cells increases their resistance toward apoptotic stimuli without affecting their glucose-induced insulin secretion.
Yang J.Y., Walicki J., Abderrahmani A., Cornu M., Waeber G., Thorens B., Widmann C., 2005. Journal of Biological Chemistry, 280 (38) pp. 32835-32842. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8B0726FA2D73]
 
GLUT8 subcellular localization and absence of translocation to the plasma membrane in PC12 cells and hippocampal neurons.
Widmer M., Uldry M., Thorens B., 2005. Endocrinology, 146 (11) pp. 4727-4736. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EECF50BD048F]
 
Incrétines, secretion d'insuline et diabète
Thorens B., 2005. Médecine sciences : M/S, 21 Spec No pp. 40-43. Peer-reviewed.
[WoS][Pmid][serval:BIB_7640ABE59DB2]
 
Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors.
Marty N., Dallaporta M., Foretz M., Emery M., Tarussio D., Bady I., Binnert C., Beermann F., Thorens B., 2005. Journal of Clinical Investigation, 115 (12) pp. 3545-3553. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_899311492768]
 
Short-term overexpression of a constitutively active form of AMP-activated protein kinase in the liver leads to mild hypoglycemia and fatty liver.
Foretz M., Ancellin N., Andreelli F., Saintillan Y., Grondin P., Kahn A., Thorens B., Vaulont S., Viollet B., 2005. Diabetes, 54 (5) pp. 1331-1339. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AD2F12020C42]
2004
 
Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis.
Thorens B., Larsen P.J., 2004/07. Current opinion in clinical nutrition and metabolic care, 7 (4) pp. 471-478. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_27014C39FE32]
 
Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain--an immunohistochemical study.
Arluison M., Quignon M., Nguyen P., Thorens B., Leloup C., Penicaud L., 2004. Journal of Chemical Neuroanatomy, 28 (3) pp. 117-136.
[DOI][WoS][Pmid][serval:BIB_9B0F61B3ECA2]
 
GIP et GLP-1: multiplicité des mécanismes régulateurs de l'insulinosécrétion
Thorens B., 2004. Journées annuelles de diabétologie de l'Hôtel-Dieu pp. 111-125.
[Pmid][serval:BIB_DA2D2136068F]
 
Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors.
Preitner F., Ibberson M., Franklin I., Binnert C., Pende M., Gjinovci A., Hansotia T., Drucker D.J., Wollheim C., Burcelin R. et al., 2004. Journal of Clinical Investigation, 113 (4) pp. 635-645. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B43DE522929C]
 
Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study.
Arluison M., Quignon M., Thorens B., Leloup C., Penicaud L., 2004. Journal of Chemical Neuroanatomy, 28 (3) pp. 137-146.
[DOI][WoS][Pmid][serval:BIB_3395A6F51BC3]
 
Impaired glucose homeostasis in mice lacking the alpha1b-adrenergic receptor subtype.
Burcelin R., Uldry M., Foretz M., Perrin C., Dacosta A., Nenniger-Tosato M., Seydoux J., Cotecchia S., Thorens B., 2004. Journal of Biological Chemistry, 279 (2) pp. 1108-1115.
[DOI][WoS][Pmid][serval:BIB_0DFE5C0BDD4B]
 
Mechanisms of glucose sensing and multiplicity of glucose sensors.
Thorens B., 2004. Annales d'Endocrinologie, 65 (1) pp. 9-12.
[DOI][WoS][Pmid][serval:BIB_204AD3CA427F]
 
Partial gene deletion of endothelial nitric oxide synthase predisposes to exaggerated high-fat diet-induced insulin resistance and arterial hypertension.
Cook S., Hugli O., Egli M., Ménard B., Thalmann S., Sartori C., Perrin C., Nicod P., Thorens B., Vollenweider P. et al., 2004. Diabetes, 53 (8) pp. 2067-2072.
[DOI][WoS][Pmid][serval:BIB_6B845B257B81]
 
Physiology of GLP-1--lessons from glucoincretin receptor knockout mice.
Thorens B., 2004. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme, 36 (11-12) pp. 766-770. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C1A1B43E6641]
 
Regulated exocytosis of an H+/myo-inositol symporter at synapses and growth cones.
Uldry M., Steiner P., Zurich M.G., Béguin P., Hirling H., Dolci W., Thorens B., 2004. The EMBO Journal, 23 (3) pp. 531-540. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_88BF8D7B4578]
 
The Facilitative glucose transporter 2: pathophysiological role in mouse and human.
Foretz M., Thorens B., 2004. pp. 175-190 dans Bröer S., Wagner C.A. (eds.) Membrane Transporter Diseases chap. 12, Kluwer Academic/Plenum Publishers.
[serval:BIB_31686]
 
The hepatoportal glucose sensor. Mechanisms of glucose sensing and signal transduction
Thorens B., 2004. pp. 327-338 dans Matschinsky F.M., Magnuson M.A (eds.) Glucokinase and glycemic diseases: from the basics to novel therapeutics, Karger.
[serval:BIB_4EB5497E1D17]
The SLC2 family of facilitated hexose and polyol transporters.
Uldry M., Thorens B., 2004. Pflügers Archiv : European Journal of Physiology, 447 (5) pp. 480-489.
[URN][DOI][WoS][Pmid][serval:BIB_72AB04FFF9E9]
 
Transcript profiling suggests that differential metabolic adaptation of mice to a high fat diet is associated with changes in liver to muscle lipid fluxes.
de Fourmestraux V., Neubauer H., Poussin C., Farmer P., Falquet L., Burcelin R., Delorenzi M., Thorens B., 2004. Journal of Biological Chemistry, 279 (49) pp. 50743-50753. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8510D08B87AB]
2003
 
Incrétines, sécrétion d'insuline et diabète
Thorens B., 2003/09. Médecine sciences : M/S, 19 (8-9) pp. 860-863. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_478FD742F151]
 
A gene knockout approach in mice to identify glucose sensors controlling glucose homeostasis.
Thorens B., 2003. Pflügers Archiv : European journal of physiology, 445 (4) pp. 482-490. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0766B726C98F]
Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice.
Cook S., Hugli O., Egli M., Vollenweider P., Burcelin R., Nicod P., Thorens B., Scherrer U., 2003. Swiss Medical Weekly, 133 (25-26) pp. 360-363. Peer-reviewed.
[URN][WoS][Pmid][serval:BIB_70867953212A]
 
Destruction of conditional insulinoma cell lines in NOD mice: a role for autoimmunity.
Cattan P., Rottembourg D., Cottet S., Tardivel I., Dupraz P., Thorens B., Boitard C., Carel J.C., 2003. Diabetologia, 46 (4) pp. 504-510. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_26630]
GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor-stimulated muscle glucose utilization.
Burcelin R., Crivelli V., Perrin C., Da Costa A., Mu J., Kahn B.B., Birnbaum M.J., Kahn C.R., Vollenweider P., Thorens B., 2003. Journal of Clinical Investigation, 111 (10) pp. 1555-1562. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_26632]
 
Gonadotropin-releasing hormone secretion from hypothalamic neurons: stimulation by insulin and potentiation by leptin.
Burcelin R., Thorens B., Glauser M., Gaillard R.C., Pralong F.P., 2003. Endocrinology, 144 (10) pp. 4484-4491. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_26634]
 
International Union of Pharmacology. XXXV. The glucagon receptor family.
Mayo K.E., Miller L.J., Bataille D., Dalle S., Göke B., Thorens B., Drucker D.J., 2003. Pharmacological Reviews, 55 (1) pp. 167-194.
[DOI][WoS][Pmid][serval:BIB_8371EFCA058E]
 
Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells.
Galbiati F., Polastri L., Thorens B., Dupraz P., Fiorina P., Cavallaro U., Christofori G., Davalli A.M., 2003. Endocrinology, 144 (5) pp. 1832-1841. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_26631]
 
Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice.
Gouyon F., Caillaud L., Carriere V., Klein C., Dalet V., Citadelle D., Kellett G.L., Thorens B., Leturque A., Brot-Laroche E., 2003. Journal of Physiology, 552 (3) pp. 823-832. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A707840A8FCC]
 
The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines.
Nikulina M.A., Sandhu N., Shamim Z., Andersen N.A., Oberson A., Dupraz P., Thorens B., Karlsen A.E., Bonny C., Mandrup-Poulsen T., 2003. Cytokine, 24 (1-2) pp. 13-24.
[DOI][WoS][Pmid][serval:BIB_506CF7D2B81D]
 
The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells.
Haefliger J.A., Tawadros T., Meylan L., Gurun S.L., Roehrich M.E., Martin D., Thorens B., Waeber G., 2003. Journal of Cell Science, 116 (Pt 8) pp. 1463-1469.
[DOI][WoS][Pmid][serval:BIB_42B18BB6B855]
2002
 
Allogeneic beta-islet cells correct diabetes and resist immune rejection.
Pericin M., Althage A., Freigang S., Hengartner H., Rolland E., Dupraz P., Thorens B., Aebischer P., Zinkernagel R.M., 2002. Proceedings of the National Academy of Sciences of the United States of America, 99 (12) pp. 8203-8206.
[DOI][WoS][Pmid][serval:BIB_1BB20FF35B00]
 
cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells.
Cottet S., Dupraz P., Hamburger F., Dolci W., Jaquet M., Thorens B., 2002. Diabetes, 51 (6) pp. 1805-1814.
[DOI][WoS][Pmid][serval:BIB_6342DC89E965]
 
Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway.
Hosokawa M., Thorens B., 2002. American journal of physiology. Endocrinology and metabolism, 282 (4) pp. E794-E801. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B02C40CCE38C]
 
GLUT2 is a high affinity glucosamine transporter.
Uldry M., Ibberson M., Hosokawa M., Thorens B., 2002. FEBS letters, 524 (1-3) pp. 199-203. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B0AD1F7C5CB6]
 
Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet.
Burcelin R., Crivelli V., Dacosta A., Roy-Tirelli A., Thorens B., 2002. American journal of physiology. Endocrinology and metabolism, 282 (4) pp. E834-E842. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_460BAF398C5C]
 
Immunolocalization of GLUTX1 in the testis and to specific brain areas and vasopressin-containing neurons.
Ibberson M., Riederer B.M., Uldry M., Guhl B., Roth J., Thorens B., 2002. Endocrinology, 143 (1) pp. 276-284. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B76795B3BACD]
 
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators.
Joost H.G., Bell G.I., Best J.D., Birnbaum M.J., Charron M.J., Chen Y.T., Doege H., James D.E., Lodish H.F., Moley K.H. et al., 2002. American journal of physiology. Endocrinology and metabolism, 282 (4) pp. E974-E976. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A2D2BE9959C4]
2001
 
Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin.
Hosokawa M., Dolci W., Thorens B., 2001/12. Biochemical and Biophysical Research Communications, 289 (5) pp. 1114-1117.
[DOI][WoS][Pmid][serval:BIB_8E5B861B6A33]
 
GLUT2 in pancreatic and extra-pancreatic gluco-detection (review).
Thorens B., 2001/12. Molecular Membrane Biology, 18 (4) pp. 265-273.
[DOI][WoS][Pmid][serval:BIB_D4101A59DCC2]
 
Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice.
Pende M., Kozma S.C., Jaquet M., Oorschot V., Burcelin R., Le Marchand-Brustel Y., Klumperman J., Thorens B., Thomas G., 2001/12. Nature, 408 (6815) pp. 994-997. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B9D4B88893AF]
 
Engineering tolerance into transplanted beta cell lines.
Thorens B., Dupraz P., Cottet S., 2001/11. Annals of the New York Academy of Sciences, 944 pp. 267-270.
[DOI][WoS][Pmid][serval:BIB_B2138C6F0319]
 
Normal kinetics of intestinal glucose absorption in the absence of GLUT2: evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum.
Stümpel F., Burcelin R., Jungermann K., Thorens B., 2001/09. Proceedings of the National Academy of Sciences of the United States of America, 98 (20) pp. 11330-11335. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0F3B9D7A1E61]
 
Glucose competence of the hepatoportal vein sensor requires the presence of an activated glucagon-like peptide-1 receptor.
Burcelin R., Da Costa A., Drucker D., Thorens B., 2001/08. Diabetes, 50 (8) pp. 1720-1728.
[DOI][WoS][Pmid][serval:BIB_1A0F365705B6]
 
Identification of a mammalian H(+)-myo-inositol symporter expressed predominantly in the brain.
Uldry M., Ibberson M., Horisberger J.D., Chatton J.Y., Riederer B.M., Thorens B., 2001/08. EMBO journal, 20 (16) pp. 4467-4477. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8DEEB384CFF5]
 
Insulin resistance, hyperlipidemia, and hypertension in mice lacking endothelial nitric oxide synthase.
Duplain H., Burcelin R., Sartori C., Cook S., Egli M., Lepori M., Vollenweider P., Pedrazzini T., Nicod P., Thorens B. et al., 2001/07. Circulation, 104 (3) pp. 342-345.
[WoS][Pmid][serval:BIB_BA2031225770]
 
Evidence that extrapancreatic GLUT2-dependent glucose sensors control glucagon secretion.
Burcelin R., Thorens B., 2001/06. Diabetes, 50 (6) pp. 1282-1289.
[DOI][WoS][Pmid][serval:BIB_8F90B2738606]
 
Alvéolite aux isocyanates chez une couturière [Isocyanate-induced alveolitis in a furniture manufacture worker]
Holtz J., Uldry C., Thorens B., 2001. Revue des Maladies Respiratoires, 18 (4 Pt 1) pp. 429-431. Peer-reviewed.
[Pmid][serval:BIB_75EDADD47A9E]
 
Lipoprotein lipase and leptin are accumulated in different secretory compartments in rat adipocytes.
Roh C., Roduit R., Thorens B., Fried S., Kandror K.V., 2001. Journal of Biological Chemistry, 276 (38) pp. 35990-35994.
[DOI][WoS][Pmid][serval:BIB_51C4A6E63228]
 
SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma.
Cottet S., Dupraz P., Hamburger F., Dolci W., Jaquet M., Thorens B., 2001. Journal of Biological Chemistry, 276 (28) pp. 25862-25870.
[DOI][WoS][Pmid][serval:BIB_2517E271E941]
 
The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review).
Joost H.G., Thorens B., 2001. Molecular Membrane Biology, 18 (4) pp. 247-256.
[DOI][WoS][Pmid][serval:BIB_828C6F313620]
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