Manuele Rebsamen

Publications | Phd and Masters theses

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24 publications

2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 |
 
A substrate-based ontology for human solute carriers.
Meixner E., Goldmann U., Sedlyarov V., Scorzoni S., Rebsamen M., Girardi E., Superti-Furga G., 2020/07. Molecular systems biology, 16 (7) pp. e9652. Peer-reviewed.
 
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Heinz L.X., Lee J., Kapoor U., Kartnig F., Sedlyarov V., Papakostas K., César-Razquin A., Essletzbichler P., Goldmann U., Stefanovic A. et al., 2020/05. Nature, 581 (7808) pp. 316-322. Peer-reviewed.
 
Insights into the transport side of the human SLC38A9 transceptor.
Scalise M., Galluccio M., Pochini L., Cosco J., Trotta M., Rebsamen M., Superti-Furga G., Indiveri C., 2019/09/01. Biochimica et biophysica acta. Biomembranes, 1861 (9) pp. 1558-1567. Peer-reviewed.
 
Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking.
Fauster A., Rebsamen M., Willmann K.L., César-Razquin A., Girardi E., Bigenzahn J.W., Schischlik F., Scorzoni S., Bruckner M., Konecka J. et al., 2019/06. Cell Death and Differentiation.
 
LZTR1 is a regulator of RAS ubiquitination and signaling
Bigenzahn Johannes W., Collu Giovanna M., Kartnig Felix, Pieraks Melanie, Vladimer Gregory I., Heinz Leonhard X., Sedlyarov Vitaly, Schischlik Fiorella, Fauster Astrid, Rebsamen Manuele et al., 2018/12/07. Science, 362 (6419) pp. 1171-1177.
 
The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification.
Sedlyarov V., Eichner R., Girardi E., Essletzbichler P., Goldmann U., Nunes-Hasler P., Srndic I., Moskovskich A., Heinz L.X., Kartnig F. et al., 2018/06/13. Cell host & microbe, 23 (6) pp. 766-774.e5. Peer-reviewed.
 
LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning
Filipek Przemyslaw A., de Araujo Mariana E.G., Vogel Georg F., De Smet Cedric H., Eberharter Daniela, Rebsamen Manuele, Rudashevskaya Elena L., Kremser Leopold, Yordanov Teodor, Tschaikner Philipp et al., 2017/12/04. Journal of Cell Biology, 216 (12) pp. 4199-4215.
 
SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1
Rebsamen Manuele, Superti-Furga Giulio, 2016/06/02. Autophagy, 12 (6) pp. 1061-1062.
 
An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client.
Bigenzahn J.W., Fauster A., Rebsamen M., Kandasamy R.K., Scorzoni S., Vladimer G.I., Müller A.C., Gstaiger M., Zuber J., Bennett K.L. et al., 2016/03. Molecular & cellular proteomics, 15 (3) pp. 1139-1150. Peer-reviewed.
 
A time-resolved molecular map of the macrophage response to VSV infection.
Kandasamy R.K., Vladimer G.I., Snijder B., Müller A.C., Rebsamen M., Bigenzahn J.W., Moskovskich A., Sabler M., Stefanovic A., Scorzoni S. et al., 2016. NPJ systems biology and applications, 2 p. 16027. Peer-reviewed.
 
Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
Dixon Scott J., Winter Georg E., Musavi Leila S., Lee Eric D., Snijder Berend, Rebsamen Manuele, Superti-Furga Giulio, Stockwell Brent R., 2015/07/17. ACS Chemical Biology, 10 (7) pp. 1604-1609.
 
The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity
Heinz Leonhard X., Baumann Christoph L., Köberlin Marielle S., Snijder Berend, Gawish Riem, Shui Guanghou, Sharif Omar, Aspalter Irene M., Müller André C., Kandasamy Richard K. et al., 2015/06. Cell Reports, 11 (12) pp. 1919-1928.
 
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
Fauster A, Rebsamen M, Huber K V M, Bigenzahn J W, Stukalov A, Lardeau C-H, Scorzoni S, Bruckner M, Gridling M, Parapatics K et al., 2015/05. Cell Death & Disease, 6 (5) pp. e1767-e1767.
 
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
Rebsamen Manuele, Pochini Lorena, Stasyk Taras, de Araújo Mariana E. G., Galluccio Michele, Kandasamy Richard K., Snijder Berend, Fauster Astrid, Rudashevskaya Elena L., Bruckner Manuela et al., 2015/03. Nature, 519 (7544) pp. 477-481.
 
Protein interaction networks in innate immunity.
Rebsamen M., Kandasamy R.K., Superti-Furga G., 2013/12. Trends in immunology, 34 (12) pp. 610-619. Peer-reviewed.
 
A reversible gene trap collection empowers haploid genetics in human cells.
Bürckstümmer T., Banning C., Hainzl P., Schobesberger R., Kerzendorfer C., Pauler F.M., Chen D., Them N., Schischlik F., Rebsamen M. et al., 2013/10. Nature methods, 10 (10) pp. 965-971. Peer-reviewed.
 
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells.
Staehli F., Ludigs K., Heinz L.X., Seguín-Estévez Q., Ferrero I., Braun M., Schroder K., Rebsamen M., Tardivel A., Mattmann C. et al., 2012. Journal of Immunology, 188 (8) pp. 3820-3828.
 
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade.
Heinz L.X., Rebsamen M., Rossi D.C., Staehli F., Schroder K., Quadroni M., Gross O., Schneider P., Tschopp J., 2012. Cell Death and Differentiation, 19 (4) pp. 722-731.
 
NLRX1/NOD5 deficiency does not affect MAVS signalling.
Rebsamen M., Vazquez J., Tardivel A., Guarda G., Curran J., Tschopp J., 2011. Cell Death and Differentiation, 18 (8) p. 1387.
 
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Poeck H., Bscheider M., Gross O., Finger K., Roth S., Rebsamen M., Hannesschläger N., Schlee M., Rothenfusser S., Barchet W. et al., 2010. Nature Immunology, 11 (1) pp. 63-69. Peer-reviewed.
 
Viruses under the control of RIP kinases.
Rebsamen M., Tschopp J., 2010. Cell Cycle, 9 (3) pp. 438-439. Peer-reviewed.
 
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB.
Rebsamen M., Heinz L.X., Meylan E., Michallet M.C., Schroder K., Hofmann K., Vazquez J., Benedict C.A., Tschopp J., 2009. EMBO reports, 10 (8) pp. 916-922. Peer-reviewed.
 
The antiviral adaptor proteins Cardif and Trif are processed and inactivated by caspases.
Rebsamen M., Meylan E., Curran J., Tschopp J., 2008/11. Cell death and differentiation, 15 (11) pp. 1804-1811. Peer-reviewed.
 
TRADD protein is an essential component of the RIG-like helicase antiviral pathway
Michallet M. C., Meylan E., Ermolaeva M. A., Vazquez J., Rebsamen M., Curran J., Poeck H., Bscheider M., Hartmann G., Konig M. et al., 2008. Immunity, 28 (5) pp. 651-661. Peer-reviewed.
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