Florent Allagnat

Publications | Mémoires et thèses

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48 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2005 |
2024
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Agius Thomas, Emsley Raffaella, Lyon Arnaud, MacArthur Michael R., Kiesworo Kevin, Faivre Anna, Stavart Louis, Lambelet Martine, Legouis David, de Seigneux Sophie et al., 2024/02/05. Nature Communications, 15 (1).
[URN][DOI][Pmid][serval:BIB_4235435871D0]
2023
Sodium Hydrosulfide Treatment During Porcine Kidney Ex Vivo Perfusion and Transplantation.
Agius T., Songeon J., Lyon A., Longchamp J., Ruttimann R., Allagnat F., Déglise S., Corpataux J.M., Golshayan D., Buhler L. et al., 2023/11. Transplantation direct, 9 (11) pp. e1508. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_E205D46FAC7F]
 
Cystathionine Gamma Lyase Is Regulated by Flow and Controls Smooth Muscle Migration in Human Saphenous Vein.
Zhao S., Deslarzes-Dubuis C., Urfer S., Lambelet M., Déglise S., Allagnat F., 2023/09/07. Antioxidants, 12 (9) p. 1731. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3ED0477D2B3C]
 
Clinical Potential of Hydrogen Sulfide in Peripheral Arterial Disease.
Bechelli C., Macabrey D., Deglise S., Allagnat F., 2023/06/09. International journal of molecular sciences, 24 (12) p. 9955. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C0DACE012352]
Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization.
Kiesworo K., MacArthur M.R., Kip P., Agius T., Macabrey D., Lambelet M., Hamard L., Ozaki C.K., Mitchell J.R., Déglise S. et al., 2023. JVS-vascular science, 4 p. 100095. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_812D6FF04BF6]
2022
Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using <sup>31</sup>P Magnetic Resonance Spectroscopic Imaging.
Agius T., Songeon J., Klauser A., Allagnat F., Longchamp G., Ruttimann R., Lyon A., Ivaniesevic J., Meier R., Déglise S. et al., 2022/10. Transplantation direct, 8 (10) pp. e1354. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D63BB4C604D7]
Sodium thiosulfate acts as a hydrogen sulfide mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerisation.
Macabrey D., Longchamp A., MacArthur M.R., Lambelet M., Urfer S., Deglise S., Allagnat F., 2022/04. EBioMedicine, 78 p. 103954. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_29D263F9FBA9]
Stapled Porcine Pericardium Displays Lower Infectivity In Vitro Than Native and Sutured Porcine Pericardium.
Del Tatto B., Le Roy D., Lambelet M., Corpataux J.M., Chakfé N., Giulieri S., Allagnat F., Roger T., Saucy F., 2022/04. The Journal of surgical research, 272 pp. 132-138. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17ED46F3E2BE]
 
Hydrogen Sulphide Release via the Angiotensin Converting Enzyme Inhibitor Zofenopril Prevents Intimal Hyperplasia in Human Vein Segments and in a Mouse Model of Carotid Artery Stenosis.
Macabrey D., Deslarzes-Dubuis C., Longchamp A., Lambelet M., Ozaki C.K., Corpataux J.M., Allagnat F., Déglise S., 2022/02. European journal of vascular and endovascular surgery, 63 (2) pp. 336-346. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_48047AB5D03F]
Clinical Use of Hydrogen Sulfide to Protect Against Intimal Hyperplasia.
Macabrey D., Longchamp A., Déglise S., Allagnat F., 2022. Frontiers in cardiovascular medicine, 9 p. 876639. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FA7E3DF9F490]
 
Sodium thiosulfate, a source of hydrogen sulfide, stimulates endothelial cell proliferation and neovascularization.
Macabrey D., Joniová J., Gasser Q., Bechelli C., Longchamp A., Urfer S., Lambelet M., Fu C.Y., Schwarz G., Wagnières G. et al., 2022. Frontiers in cardiovascular medicine, 9 p. 965965. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B3BEAE5B7756]
Vascular smooth muscle cells in intimal hyperplasia, an update.
Déglise S., Bechelli C., Allagnat F., 2022. Frontiers in physiology, 13 p. 1081881. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_84BC9965E4A7]
2021
 
Differential role of nicotinamide adenine dinucleotide deficiency in acute and chronic kidney disease.
Faivre A., Katsyuba E., Verissimo T., Lindenmeyer M., Rajaram R.D., Naesens M., Heckenmeyer C., Mottis A., Feraille E., Cippà P. et al., 2021/01/01. Nephrology, dialysis, transplantation, 36 (1) pp. 60-68. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_73C83D588458]
2020
 
Targeting connexin37 alters angiogenesis and arteriovenous differentiation in the developing mouse retina.
Hamard L., Santoro T., Allagnat F., Meda P., Nardelli-Haefliger D., Alonso F., Haefliger J.A., 2020/06. FASEB journal, 34 (6) pp. 8234-8249. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_79F060AF8AB9]
2019
 
Hydrogen sulfide-releasing peptide hydrogel limits the development of intimal hyperplasia in human vein segments.
Longchamp A., Kaur K., Macabrey D., Dubuis C., Corpataux J.M., Déglise S., Matson J.B., Allagnat F., 2019/10/01. Acta biomaterialia, 97 pp. 374-384. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E03968098A3C]
2018
Cellular effects of AP102, a somatostatin analog with balanced affinities for the hSSTR2 and hSSTR5 receptors.
Streuli J., Harris A.G., Cottiny C., Allagnat F., Daly A.F., Grouzmann E., Abid K., 2018/04. Neuropeptides, 68 pp. 84-89. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C117C7B22DCF]
Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis.
Lambelet M., Terra L.F., Fukaya M., Meyerovich K., Labriola L., Cardozo A.K., Allagnat F., 2018/01/24. Cell death & disease, 9 (2) p. 96. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CE4715907BDD]
2017
 
Targeting Cx40 (Connexin40) Expression or Function Reduces Angiogenesis in the Developing Mouse Retina.
Haefliger J.A., Allagnat F., Hamard L., Le Gal L., Meda P., Nardelli-Haefliger D., Génot E., Alonso F., 2017/11. Arteriosclerosis, thrombosis, and vascular biology, 37 (11) pp. 2136-2146. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3B07F939D345]
 
Connexin37 reduces smooth muscle cell proliferation and intimal hyperplasia in a mouse model of carotid artery ligation.
Allagnat F., Dubuis C., Lambelet M., Le Gal L., Alonso F., Corpataux J.M., Déglise S., Haefliger J.A., 2017/06/01. Cardiovascular research, 113 (7) pp. 805-816. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B56A5A19C4D1]
2016
 
Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation.
Meyerovich K., Ortis F., Allagnat F., Cardozo A.K., 2016/07. Journal of molecular endocrinology, 57 (1) pp. R1-R17. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2ECD7618EAC4]
 
Nitric Oxide Deficit Drives Intimal Hyperplasia in Mouse Models of Hypertension.
Allagnat F., Haefliger J.A., Lambelet M., Longchamp A., Bérard X., Mazzolai L., Corpataux J.M., Déglise S., 2016/05. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 51 (5) pp. 733-742. Peer-reviewed.
[DOI][Pmid][serval:BIB_C0A2446DFA5B]
 
Store-operated Ca2+ entry: a key component of the insulin secretion machinery.
Sabourin J., Allagnat F., 2016/04. Journal of molecular endocrinology, 57 (3) pp. F35-F39. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_37A8D5B70DAF]
Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets.
Tugay K., Guay C., Marques A.C., Allagnat F., Locke J.M., Harries L.W., Rutter G.A., Regazzi R., 2016. Diabetologia, 59 (1) pp. 161-169. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_380DB5121536]
2015
Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia.
Longchamp A., Allagnat F., Alonso F., Kuppler C., Dubuis C., Ozaki C.K., Mitchell J.R., Berceli S., Corpataux J.M., Déglise S. et al., 2015. Plos One, 10 (9) pp. e0138847. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_94769B9A0BE8]
 
Role of Connexins and Pannexins in the Pancreas.
Cigliola V., Allagnat F., Berchtold L.A., Lamprianou S., Haefliger J.A., Meda P., 2015. Pancreas, 44 (8) pp. 1234-1244. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B58B5436A0DA]
 
Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells.
Sabourin J., Le Gal L., Saurwein L., Haefliger J.A., Raddatz E., Allagnat F., 2015. Journal of Biological Chemistry, 290 (51) pp. 30530-30539. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_83FCF995331B]
2014
 
Procedure for human saphenous veins ex vivo perfusion and external reinforcement.
Longchamp A., Allagnat F., Berard X., Alonso F., Haefliger J.A., Deglise S., Corpataux J.M., 2014. Journal of Visualized Experiments : Jove 92 pp. e52079.
[DOI][WoS][Pmid][serval:BIB_B00F5712EB72]
 
The use of external mesh reinforcement to reduce intimal hyperplasia and preserve the structure of human saphenous veins.
Longchamp A., Alonso F., Dubuis C., Allagnat F., Berard X., Meda P., Saucy F., Corpataux J.M., Déglise S., Haefliger J.A., 2014. Biomaterials, 35 (9) pp. 2588-2599. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F9DA82EBAC80]
2013
 
Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.
Allagnat F., Klee P., Cardozo A.K., Meda P., Haefliger J.A., 2013. Cell Death and Differentiation, 20 (12) pp. 1742-1752.
[DOI][WoS][Pmid][serval:BIB_615837888C88]
Connexins and M3 muscarinic receptors contribute to heterogeneous Ca(2+) signaling in mouse aortic endothelium.
Boittin F.X., Alonso F., Le Gal L., Allagnat F., Bény J.L., Haefliger J.A., 2013. Cellular physiology and biochemistry, 31 (1) pp. 166-178. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_855794F06456]
 
Hyperglycemia downregulates Connexin36 in pancreatic islets via the upregulation of ICER-1/ICER-1γ.
Haefliger J.A., Rohner-Jeanrenaud F., Caille D., Charollais A., Meda P., Allagnat F., 2013. Journal of Molecular Endocrinology, 51 (1) pp. 49-58. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3E35AE378448]
Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles.
Haefliger J.A., Martin D., Favre D., Petremand Y., Mazzolai L., Abderrahmani A., Meda P., Waeber G., Allagnat F., 2013. PLOS One, 8 (1) pp. e55198.
[URN][DOI][WoS][Pmid][serval:BIB_70DABA808272]
2012
 
Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes.
Marhfour I., Lopez X.M., Lefkaditis D., Salmon I., Allagnat F., Richardson S.J., Morgan N.G., Eizirik D.L., 2012/09. Diabetologia, 55 (9) pp. 2417-2420. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_5E5D8BB318D0]
 
Differential usage of NF-κB activating signals by IL-1β and TNF-α in pancreatic beta cells.
Ortis F., Miani M., Colli M.L., Cunha D.A., Gurzov E.N., Allagnat F., Chariot A., Eizirik D.L., 2012/04/05. FEBS letters, 586 (7) pp. 984-989. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1D8DC9368E48]
 
C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells.
Allagnat F., Fukaya M., Nogueira T.C., Delaroche D., Welsh N., Marselli L., Marchetti P., Haefliger J.A., Eizirik D.L., Cardozo A.K., 2012. Cell Death and Differentiation, 19 (11) pp. 1836-1846.
[DOI][WoS][Pmid][serval:BIB_DC763804A6EE]
 
Cx36 Is a Target of Beta2/NeuroD1, Which Associates with Prenatal Differentiation of Insulin-producing β Cells.
Nlend R.N., Aït-Lounis A., Allagnat F., Cigliola V., Charollais A., Reith W., Haefliger J.A., Meda P., 2012. Journal of Membrane Biology, 245 (5-6) pp. 263-273. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_16DFDB396AFB]
 
HDLs protect pancreatic β-cells against ER stress by restoring protein folding and trafficking.
Pétremand J., Puyal J., Chatton J.Y., Duprez J., Allagnat F., Frias M., James R.W., Waeber G., Jonas J.C., Widmann C., 2012. Diabetes, 61 (5) pp. 1100-1111.
[URN][DOI][WoS][Pmid][serval:BIB_A0510DB24A81]
Specific Silencing of the REST Target Genes in Insulin-Secreting Cells Uncovers Their Participation in Beta Cell Survival.
Martin D., Allagnat F., Gesina E., Caille D., Gjinovci A., Waeber G., Meda P., Haefliger J.A., 2012. Plos One, 7 (9) pp. e45844. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8BE277EF6A16]
2011
Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.
Colli M.L., Nogueira T.C., Allagnat F., Cunha D.A., Gurzov E.N., Cardozo A.K., Roivainen M., Op de Beeck A., Eizirik D.L., 2011/09. PLoS pathogens, 7 (9) pp. e1002267. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_062C5C1A6E9B]
 
Heterozygous inactivation of the Na/Ca exchanger increases glucose-induced insulin release, β-cell proliferation, and mass.
Nguidjoe E., Sokolow S., Bigabwa S., Pachera N., D'Amico E., Allagnat F., Vanderwinden J.M., Sener A., Manto M., Depreter M. et al., 2011/08. Diabetes, 60 (8) pp. 2076-2085. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E5FC619FECF3]
 
Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis.
Allagnat F., Cunha D., Moore F., Vanderwinden J.M., Eizirik D.L., Cardozo A.K., 2011/02. Cell death and differentiation, 18 (2) pp. 328-337. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D7C6851CCAAF]
 
Connexins protect mouse pancreatic β cells against apoptosis.
Klee P., Allagnat F., Pontes H., Cederroth M., Charollais A., Caille D., Britan A., Haefliger J.A., Meda P., 2011. Journal of Clinical Investigation, 121 (12) pp. 4870-4879.
[DOI][WoS][Pmid][serval:BIB_D563A9D1CAC6]
Role for inducible cAMP early repressor in promoting pancreatic beta cell dysfunction evoked by oxidative stress in human and rat islets.
Favre D., Niederhauser G., Fahmi D., Plaisance V., Brajkovic S., Beeler N., Allagnat F., Haefliger J.A., Regazzi R., Waeber G. et al., 2011. Diabetologia, 54 (9) pp. 2337-2346.
[URN][DOI][WoS][Pmid][serval:BIB_4C94EFEF3162]
2010
 
Plasma membrane Ca2+-ATPase overexpression depletes both mitochondrial and endoplasmic reticulum Ca2+ stores and triggers apoptosis in insulin-secreting BRIN-BD11 cells.
Jiang L., Allagnat F., Nguidjoe E., Kamagate A., Pachera N., Vanderwinden J.M., Brini M., Carafoli E., Eizirik D.L., Cardozo A.K. et al., 2010/10/01. The Journal of biological chemistry, 285 (40) pp. 30634-30643. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2AA97B121EE9]
 
Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis.
Allagnat F., Christulia F., Ortis F., Pirot P., Lortz S., Lenzen S., Eizirik D.L., Cardozo A.K., 2010/06. Diabetologia, 53 (6) pp. 1120-1130. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1FB486CBB448]
2009
 
Connexins, diabetes and the metabolic syndrome.
Hamelin R., Allagnat F., Haefliger J.A., Meda P., 2009. Current Protein & Peptide Science, 10 (1) pp. 18-29. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_83E658358E61]
2008
 
ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.
Allagnat F., Alonso F., Martin D., Abderrahmani A., Waeber G., Haefliger J.A., 2008. Journal of Biological Chemistry, 283 (9) pp. 5226-5234. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DD9E73B6B269]
2005
 
Glucose represses connexin36 in insulin-secreting cells.
Allagnat F., Martin D., Condorelli D.F., Waeber G., Haefliger J.A., 2005. Journal of cell science, 118 (Pt 22) pp. 5335-44. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_962299E40484]
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