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Pascal Schneider

Coordonnées Enseignements Publications  
Publications | Mémoires et thèses

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Alvarez A., Lagos-Cabré R., Kong M., Cárdenas A., Burgos-Bravo F., Schneider P., Quest A.F., Leyton L., Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration. Biochimica et Biophysica Acta 1863(9), pp. 2175-2188, 2016. [DOI] [Web of Science] [Pubmed] ok

Chypre M., Seaman J., Cordeiro O.G., Willen L., Knoop K.A., Buchanan A., Sainson R.C., Williams I.R., Yagita H., Schneider P. et al., Characterization and application of two RANK-specific antibodies with different biological activities. Immunology Letters 171, pp. 5-14, 2016. [DOI] [Web of Science] [Pubmed] ok

Del Rio M.L., Fernandez-Renedo C., Chaloin O., Scheu S., Pfeffer K., Shintani Y., Perez-Simon J.A., Schneider P., Rodriguez-Barbosa J.I., Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells. mAbs 8(3), pp. 478-490, 2016. [DOI] [Web of Science] [Pubmed] ok

Garcin C.L., Huttner K.M., Kirby N., Schneider P., Hardman M.J., Ectodysplasin a pathway contributes to human and murine skin repair. Journal of Investigative Dermatology 136(5), pp. 1022-1030, 2016. [DOI] [Web of Science] [Pubmed]

Kowalczyk-Quintas C., Schuepbach-Mallepell S., Vigolo M., Willen L., Tardivel A., Smulski C.R., Zheng T.S., Gommerman J., Hess H., Gottenberg J.E. et al., Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia. Journal of Biological Chemistry 291(38), pp. 19826-19834, 2016. [DOI] [Web of Science] [Pubmed] ok

Maskos K., Lammens A., Tan S.L., Hess H., Palinsky W., Schneider P., Jiang X., Data for the crystal structure of APRIL-BAFF-BAFF heterotrimer. Data In Brief 6, pp. 438-444, 2016. [Document] [DOI] [Pubmed] ok


Allam R., Maillard M.H., Tardivel A., Chennupati V., Bega H., Yu C.W., Velin D., Schneider P., Maslowski K.M., Epithelial NAIPs protect against colonic tumorigenesis. Journal of Experimental Medicine 212(3), pp. 369-383, 2015. [DOI] [Web of Science] [Pubmed]

François A., Gombault A., Villeret B., Alsaleh G., Fanny M., Gasse P., Adam S.M., Crestani B., Sibilia J., Schneider P. et al., B cell activating factor is central to bleomycin- and IL-17-mediated experimental pulmonary fibrosis. Journal of Autoimmunity 56, pp. 1-11, 2015. [DOI] [Web of Science] [Pubmed]

Grosjean F., Nasi S., Schneider P., Chobaz V., Liu A., Mordasini V., Moullec K., Vezzoni P., Lavanchy C., Busso N. et al., Dendritic Cells Cause Bone Lesions in a New Mouse Model of Histiocytosis. Plos One 10(8), p. e0133917, 2015. [DOI] [Web of Science] [Pubmed] ok

Johnston A.J., Murphy K.T., Jenkinson L., Laine D., Emmrich K., Faou P., Weston R., Jayatilleke K.M., Schloegel J., Talbo G. et al., Targeting of Fn14 Prevents Cancer-Induced Cachexia and Prolongs Survival. Cell 162(6), pp. 1365-1378, 2015. [DOI] [Web of Science] [Pubmed]

Kowalczyk-Quintas C., Schuepbach-Mallepell S., Willen L., Smith T.K., Huttner K., Kirby N., Headon D.J., Schneider P., Pharmacological stimulation of edar signaling in the adult enhances sebaceous gland size and function. Journal of Investigative Dermatology 135(2), pp. 359-368, 2015. [DOI] [Web of Science] [Pubmed]

Lugrin J., Parapanov R., Rosenblatt-Velin N., Rignault-Clerc S., Feihl F., Waeber B., Müller O., Vergely C., Zeller M., Tardivel A. et al., Cutting edge: IL-1α is a crucial danger signal triggering acute myocardial inflammation during myocardial infarction. Journal of Immunology 194(2), pp. 499-503, 2015. [DOI] [Web of Science] [Pubmed] ok

Schuepbach-Mallepell S., Das D., Willen L., Vigolo M., Tardivel A., Lebon L., Kowalczyk-Quintas C., Nys J., Smulski C., Zheng T.S. et al., Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties. Journal of Biological Chemistry 290(26), pp. 16330-16342, 2015. [DOI] [Web of Science] [Pubmed] ok

Voutilainen M., Lindfors P.H., Trela E., Lönnblad D., Shirokova V., Elo T., Rysti E., Schmidt-Ullrich R., Schneider P., Mikkola M.L., Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway. Plos Genetics 11(11), p. e1005676, 2015. [DOI] [Web of Science] [Pubmed]

Wild J., Schmiedel B.J., Maurer A., Raab S., Prokop L., Stevanović S., Dörfel D., Schneider P., Salih H.R., Neutralization of (NK-cell-derived) B-cell activating factor by Belimumab restores sensitivity of chronic lymphoid leukemia cells to direct and Rituximab-induced NK lysis. Leukemia 29(8), pp. 1676-1683, 2015. [DOI] [Web of Science] [Pubmed] ok

Woess C., Tuzlak S., Labi V., Drach M., Bertele D., Schneider P., Villunger A., Combined loss of the BH3-only proteins Bim and Bmf restores B-cell development and function in TACI-Ig transgenic mice. Cell Death and Differentiation 22(9), pp. 1477-1488, 2015. [DOI] [Web of Science] [Pubmed]


Del Rio M.L., Fernandez-Renedo C., Scheu S., Pfeffer K., Shintani Y., Kronenberg M., Chaloin O., Schneider P., Rodriguez-Barbosa J.I., Therapeutic Blockade of LIGHT Interaction With Herpesvirus Entry Mediator and Lymphotoxin β Receptor Attenuates In Vivo Cytotoxic Allogeneic Responses. Transplantation 98(11), pp. 1165-1174, 2014. [DOI] [Web of Science] [Pubmed]

Hermes K., Schneider P., Krieg P., Dang A.T., Huttner K., Schneider H., Prenatal therapy in developmental disorders: drug targeting via intra-amniotic injection to treat X-linked hypohidrotic ectodermal dysplasia. Journal of Investigative Dermatology 134(12), pp. 2985-2987, 2014. [DOI] [Web of Science] ok

Kowalczyk-Quintas C., Schneider P., Ectodysplasin A (EDA) - EDA receptor signalling and its pharmacological modulation. Cytokine and Growth Factor Reviews 25(2), pp. 195-203, 2014. [DOI] [Web of Science] [Pubmed]

Kowalczyk-Quintas C., Willen L., Dang A.T., Sarrasin H., Tardivel A., Hermes K., Schneider H., Gaide O., Donzé O., Kirby N. et al., Generation and characterization of function-blocking anti-ectodysplasin A (EDA) monoclonal antibodies that induce ectodermal dysplasia. Journal of Biological Chemistry 289(7), pp. 4273-4285, 2014. [DOI] [Web of Science] [Pubmed]

Pieper K., Rizzi M., Speletas M., Smulski C.R., Sic H., Kraus H., Salzer U., Fiala G.J., Schamel W.W., Lougaris V. et al., A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency. Journal of Allergy and Clinical Immunology 133(4), pp. 1222-1225.e10, 2014. [DOI] [Web of Science] [Pubmed] ok

Schneider P., Willen L., Smulski C.R., Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members. Methods in Enzymology 545, pp. 103-125, 2014. [DOI] [Web of Science] [Pubmed]

Vincent F.B., Morand E.F., Schneider P., Mackay F., The BAFF/APRIL system in SLE pathogenesis. Nature Reviews. Rheumatology 10(6), pp. 365-373, 2014. [DOI] [Web of Science] [Pubmed]


del Rio M.L., Schneider P., Fernandez-Renedo C., Perez-Simon J.A., Rodriguez-Barbosa J.I., LIGHT/HVEM/LTβR interaction as a target for the modulation of the allogeneic immune response in transplantation. American Journal of Transplantation 13(3), pp. 541-551, 2013. [DOI] [Web of Science] [Pubmed]

Kong M., Muñoz N., Valdivia A., Alvarez A., Herrera-Molina R., Cárdenas A., Schneider P., Burridge K., Quest A.F., Leyton L., Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4. Biochimica et Biophysica Acta. Molecular Cell Research 1833(6), pp. 1409-1420, 2013. [DOI] [Web of Science] [Pubmed]

Nys J., Smulski C.R., Tardivel A., Willen L., Kowalczyk C., Donzé O., Huard B., Hess H., Schneider P., No Evidence That Soluble TACI Induces Signalling via Membrane-Expressed BAFF and APRIL in Myeloid Cells. PLoS One 8(4), p. e61350, 2013. [Document] [DOI] [Web of Science] [Pubmed]

Pellegrini M., Willen L., Perroud M., Krushinskie D., Strauch K., Cuervo H., Day E.S., Schneider P., Zheng T.S., Structure of the extracellular domains of human and Xenopus Fn14: implications in the evolution of TWEAK and Fn14 interactions. FEBS Journal 280(8), pp. 1818-1829, 2013. [DOI] [Web of Science] [Pubmed]

Schmiedel B.J., Nuebling T., Steinbacher J., Malinovska A., Wende C.M., Azuma M., Schneider P., Grosse-Hovest L., Salih H.R., Receptor activator for NF-κB ligand in acute myeloid leukemia: expression, function, and modulation of NK cell immunosurveillance. Journal of Immunology 190(2), pp. 821-831, 2013. [DOI] [Web of Science] [Pubmed]

Schmiedel B.J., Scheible C.A., Nuebling T., Kopp H.G., Wirths S., Azuma M., Schneider P., Jung G., Grosse-Hovest L., Salih H.R., RANKL expression, function, and therapeutic targeting in multiple myeloma and chronic lymphocytic leukemia. Cancer Research 73(2), pp. 683-694, 2013. [DOI] [Web of Science] [Pubmed]

Smith W., Tomasec P., Aicheler R., Loewendorf A., Nemčovičová I., Wang E.C., Stanton R.J., Macauley M., Norris P., Willen L. et al., Human cytomegalovirus glycoprotein UL141 targets the TRAIL death receptors to thwart host innate antiviral defenses. Cell Host and Microbe 13(3), pp. 324-335, 2013. [DOI] [Web of Science] [Pubmed]

Smulski C.R., Beyrath J., Decossas M., Chekkat N., Wolff P., Estieu-Gionnet K., Guichard G., Speiser D., Schneider P., Fournel S., Cysteine-rich Domain 1 of CD40 Mediates Receptor Self-assembly. Journal of Biological Chemistry 288(15), pp. 10914-10922, 2013. [DOI] [Web of Science] [Pubmed]

Tanos T., Sflomos G., Echeverria P.C., Ayyanan A., Gutierrez M., Delaloye J.F., Raffoul W., Fiche M., Dougall W., Schneider P. et al., Progesterone/RANKL is a major regulatory axis in the human breast. Science Translational Medicine 5(182), p. 182ra55, 2013. [DOI] [Web of Science] [Pubmed] ok

Tappy L., Egli L., Lecoultre V., Schneider P., Effects of fructose-containing caloric sweeteners on resting energy expenditure and energy efficiency: a review of human trials. Nutrition and Metabolism 10(1), p. 54, 2013. [Document] [DOI] [Web of Science] [Pubmed]

Zhang N., Wang X., Huo Q., Li X., Wang H., Schneider P., Hu G., Yang Q., The Oncogene Metadherin Modulates the Apoptotic Pathway Based on the Tumor Necrosis Factor Superfamily Member TRAIL (Tumor Necrosis Factor-related Apoptosis-inducing Ligand) in Breast Cancer. Journal of Biological Chemistry 288(13), pp. 9396-9407, 2013. [DOI] [Web of Science] [Pubmed]


Drexler S.K., Bonsignore L., Masin M., Tardivel A., Jackstadt R., Hermeking H., Schneider P., Gross O., Tschopp J., Yazdi A.S., Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America 109(45), pp. 18384-18389, 2012. [DOI] [Web of Science] [Pubmed]

Heinz L.X., Rebsamen M., Rossi D.C., Staehli F., Schroder K., Quadroni M., Gross O., Schneider P., Tschopp J., The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. Cell Death and Differentiation 19(4), pp. 722-731, 2012. [DOI] [Web of Science] [Pubmed]

Herrera-Molina R., Frischknecht R., Maldonado H., Seidenbecher C.I., Gundelfinger E.D., Hetz C., Aylwin Mde L, Schneider P., Quest A.F., Leyton L., Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1. PLoS One 7(3), p. e34295, 2012. [Document] [DOI] [Web of Science] [Pubmed]

Kimberley F.C., van der Sloot A.M., Guadagnoli M., Cameron K., Schneider P., Marquart J.A., Versloot M., Serrano L., Medema J.P., The design and characterization of receptor-selective APRIL variants. Journal of Biological Chemistry 287(44), pp. 37434-37446, 2012. [DOI] [Web of Science] [Pubmed]

Lefebvre S., Fliniaux I., Schneider P., Mikkola M.L., Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development. Journal of Investigative Dermatology 132(4), pp. 1094-1102, 2012. [DOI] [Web of Science] [Pubmed]

Voutilainen M., Lindfors P.H., Lefebvre S., Ahtiainen L., Fliniaux I., Rysti E., Murtoniemi M., Schneider P., Schmidt-Ullrich R., Mikkola M.L., Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB. Proceedings of the National Academy of Sciences of the United States of America 109(15), pp. 5744-5749, 2012. [DOI] [Web of Science] [Pubmed] ok


Bacchelli C., Buckland K.F., Buckridge S., Salzer U., Schneider P., Thrasher A.J., Gaspar H.B., The C76R transmembrane activator and calcium modulator cyclophilin ligand interactor mutation disrupts antibody production and B-cell homeostasis in heterozygous and homozygous mice. Journal of Allergy and Clinical Immunology 127(5), pp. 1253-9.e13, 2011. [DOI] [Web of Science] [Pubmed]

Boeglin E., Smulski C.R., Brun S., Milosevic S., Schneider P., Fournel S., Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells. PLoS One 6(10), p. e25542, 2011. [Document] [DOI] [Web of Science] [Pubmed]

Bossen C., Tardivel A., Willen L., Fletcher C.A., Perroud M., Beermann F., Rolink A.G., Scott M.L., Mackay F., Schneider P., Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses. European Journal of Immunology 41(3), pp. 787-797, 2011. [DOI] [Web of Science] [Pubmed]

Fuertes Marraco S.A., Scott C.L., Bouillet P., Ives A., Masina S., Vremec D., Jansen E.S., O'Reilly L.A., Schneider P., Fasel N. et al., Type I interferon drives dendritic cell apoptosis via multiple BH3-only proteins following activation by PolyIC in vivo. PLoS One 6(6), p. e20189, 2011. [Document] [DOI] [Web of Science] [Pubmed]

Ganeff C., Remouchamps C., Boutaffala L., Benezech C., Galopin G., Vandepaer S., Bouillenne F., Ormenese S., Chariot A., Schneider P. et al., Induction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor. Molecular and Cellular Biology 31(21), pp. 4319-4334, 2011. [DOI] [Web of Science] [Pubmed]

Henríquez M., Herrera-Molina R., Valdivia A., Alvarez A., Kong M., Muñoz N., Eisner V., Jaimovich E., Schneider P., Quest A.F. et al., ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation. Journal of Cell Science 124(Pt 9), pp. 1581-1588, 2011. [DOI] [Web of Science] [Pubmed]

Kowalczyk C., Dunkel N., Willen L., Casal M.L., Mauldin E.A., Gaide O., Tardivel A., Badic G., Etter A.L., Favre M. et al., Molecular and therapeutic characterization of anti-ectodysplasin A receptor (EDAR) agonist monoclonal antibodies. Journal of Biological Chemistry 286(35), pp. 30769-30779, 2011. [DOI] [Web of Science] [Pubmed]

Michaelson J.S., Amatucci A., Kelly R., Su L., Garber E., Day E.S., Berquist L., Cho S., Li Y., Parr M. et al., Development of an Fn14 agonistic antibody as an anti-tumor agent. mAbs 3(4), pp. 362-375, 2011. [DOI] [Web of Science] [Pubmed]

Turchinovich G., Vu T.T., Frommer F., Kranich J., Schmid S., Alles M., Loubert J.B., Goulet J.P., Zimber-Strobl U., Schneider P. et al., Programming of marginal zone B-cell fate by basic Kruppel-like factor (BKLF/KLF3). Blood 117(14), pp. 3780-3792, 2011. [DOI] [Web of Science] [Pubmed]


Beleut M., Rajaram R.D., Caikovski M., Ayyanan A., Germano D., Choi Y., Schneider P., Brisken C., Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland. Proceedings of the National Academy of Sciences of the United States of America 107(7), pp. 2989-2994, 2010. [DOI] [Web of Science] [Pubmed] ok

Mues G., Tardivel A., Willen L., Kapadia H., Seaman R., Frazier-Bowers S., Schneider P., D'Souza R.N., Functional analysis of Ectodysplasin-A mutations causing selective tooth agenesis. European Journal of Human Genetics 18(1), pp. 19-25, 2010. [Document] [DOI] [Web of Science] [Pubmed] ok

Schneider P., The beautiful structures of BAFF, APRIL and their receptors. In: Cancro M.P. (eds.) BLyS ligands and receptors. Contemporary Immunology, Humana Press, Totowa, NJ, pp. 1-18, 2010. [Document] [url site éditeur] [DOI]

Schneider P., Huard B., Buffy's, B-cells, and membrane BAFF. Arthritis & Rheumatism 62(5), pp. 1557-1558, 2010. [Document] [DOI] [Web of Science]

Swee L.K., Tardivel A., Schneider P., Rolink A., Rescue of the mature B cell compartment in BAFF-deficient mice by treatment with recombinant Fc-BAFF. Immunology Letters 131(1), pp. 40-48, 2010. [Document] [DOI] [Web of Science] [Pubmed] ok


Avalos A.M., Valdivia A.D., Muñoz N., Herrera-Molina R., Tapia J.C., Lavandero S., Chiong M., Burridge K., Schneider P., Quest A.F. et al., Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. Journal of Cell Science 122(Pt 19), pp. 3462-3471, 2009. [DOI] [Web of Science] [Pubmed]

Back J., Malchiodi E.L., Cho S., Scarpellino L., Schneider P., Kerzic M.C., Mariuzza R.A., Held W., Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity 31(4), pp. 598-608, 2009. [DOI] [Web of Science] [Pubmed] ok

Bessa J., Jegerlehner A., Hinton H.J., Pumpens P., Saudan P., Schneider P., Bachmann M.F., Alveolar macrophages and lung dendritic cells sense RNA and drive mucosal IgA responses. Journal of Immunology 183(6), pp. 3788-3799, 2009. [DOI] [Web of Science] [Pubmed] ok

Guarda G., Dostert C., Staehli F., Cabalzar K., Castillo R., Tardivel A., Schneider P., Tschopp J., T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. Nature 460(7252), pp. 269-273, 2009. [DOI] [Web of Science] [Pubmed] ok

Guichard G., Trouche N., Wieckowski S., Sun W., Chaloin O., Bianco A., Hoebeke J., Schneider P., Fournel S., Rationally-designed multivalent architectures for mimicking homotrimers of CD40L, a member of the TNF superfamily. In: Del Valle S., Escher E., Lubell W.D. (eds.) Peptides for youth. Advances in experimental medicine and biology 611(7), Springer, New York, pp. 355-357, 2009. [DOI] [Web of Science] [Pubmed] ok

Kassahn D., Nachbur U., Conus S., Micheau O., Schneider P., Simon H.U., Brunner T., Distinct requirements for activation-induced cell surface expression of preformed Fas/CD95 ligand and cytolytic granule markers in T cells. Cell Death and Differentiation 16(1), pp. 115-124, 01-2009. [DOI] [Web of Science] [Pubmed] ok

Mackay F., Schneider P., Cracking the BAFF code. Nature reviews. Immunology 9(7), pp. 491-502, 2009. [Document] [DOI] [Web of Science] [Pubmed] ok

Mauldin E.A., Gaide O., Schneider P., Casal M.L., Neonatal treatment with recombinant ectodysplasin prevents respiratory disease in dogs with X-linked ectodermal dysplasia. American Journal of Medical Genetics. Part A 149A(9), pp. 2045-2049, 2009. [DOI] [Web of Science] [Pubmed]

Narasimamurthy R., Geuking P., Ingold K., Willen L., Schneider P., Basler K., Structure-function analysis of Eiger, the Drosophila TNF homolog. Cell Research 19(3), pp. 392-394, 02-2009. [DOI] [Web of Science] [Pubmed] ok

Salzer U., Bacchelli C., Buckridge S., Pan-Hammarström Q., Jennings S., Lougaris V., Bergbreiter A., Hagena T., Birmelin J., Plebani A. et al., Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. Blood 113(9), pp. 1967-1976, 2009. [DOI] [Web of Science] [Pubmed] ok

Swee L.K., Ingold-Salamin K., Tardivel A., Willen L., Gaide O., Favre M., Demotz S., Mikkola M., Schneider P., Biological activity of ectodysplasin A is conditioned by its collagen and heparan sulfate proteoglycan-binding domains. Journal of Biological Chemistry 284(40), pp. 27567-27576, 10-2009. [Document] [DOI] [Web of Science] [Pubmed] ok

Willett B.J., McMonagle E.L., Logan N., Schneider P., Hosie M.J., Enforced covalent trimerisation of soluble feline CD134 (OX40)-ligand generates a functional antagonist of feline immunodeficiency virus. Molecular Immunology 46(6), pp. 1020-1030, 2009. [DOI] [Web of Science] [Pubmed] ok


Belnoue E., Pihlgren M., McGaha T.L., Tougne C., Rochat A.F., Bossen C., Schneider P., Huard B., Lambert P.H., Siegrist C.A., APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood 111(5), pp. 2755-2764, 2008. [Document] [DOI] [Web of Science] [Pubmed]

Bossen C., Cachero T.G., Tardivel A., Ingold K., Willen L., Dobles M., Scott M.L., Maquelin A., Belnoue E., Siegrist C.A. et al., TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts. Blood 111(3), pp. 1004-1012, 2008. [DOI] [Web of Science] [Pubmed] ok

Farley S.M., Purdy D.E., Ryabinina O.P., Schneider P., Magun B.E., Iordanov M.S., Fas ligand-induced proinflammatory transcriptional responses in reconstructed human epidermis. Recruitment of the epidermal growth factor receptor and activation of MAP kinases. Journal of Biological Chemistry 283(2), pp. 919-928, 2008. [Document] [DOI] [Web of Science] [Pubmed]

Hermosilla T., Muñoz D., Herrera-Molina R., Valdivia A., Muñoz N., Nham S.U., Schneider P., Burridge K., Quest A.F., Leyton L., Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. Biochimica et Biophysica Acta-Molecular Cell Research 1783(6), pp. 1111-1120, 06-2008. [DOI] [Web of Science] [Pubmed] ok

Huard B., McKee T., Bosshard C., Durual S., Matthes T., Myit S., Donze O., Frossard C., Chizzolini C., Favre C. et al., APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa. Journal of Clinical Investigation 118(8), pp. 2887-2895, 2008. [DOI] [Web of Science] [Pubmed] ok

Mackay F., Schneider P., TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine and Growth Factor Reviews 19(3-4), pp. 263-276, 2008. [DOI] [Web of Science] [Pubmed]

Massacand J.C., Kaiser P., Ernst B., Tardivel A., Bürki K., Schneider P., Harris N.L., Intestinal bacteria condition dendritic cells to promote IgA production. PLoS ONE 3(7), p. e2588, 2008. [Document] [DOI] [Web of Science] [Pubmed] ok

Pappu B.P., Borodovsky A., Zheng T.S., Yang X., Wu P., Dong X., Weng S., Browning B., Scott M.L., Ma L. et al., TL1A-DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease. Journal of Experimental Medicine 205(5), pp. 1049-1062, 05-2008. [DOI] [Web of Science] [Pubmed] ok

Roosnek E., Schneider P., Huard B., Heparan sulfate proteoglycans, Fc receptors, and DC suppression. Blood 112(3), pp. 915-6; author reply 916-7, 08-2008. [DOI] [Web of Science] [Pubmed] ok

Schneider P., Signaling by TNF and related ligands. In: Epstein C., Erickson R., Wynshaw-Boris A. (eds.) Inborn Errors of Development. 2nd edition, Oxford monographs on medical genetics 54, Oxford University Press, Oxford, pp. 433-441, 2008.

Tu W., Lau Y.L., Zheng J., Liu Y., Chan P.L., Mao H., Dionis K., Schneider P., Lewis D.B., Efficient generation of human alloantigen-specific CD4+ regulatory T cells from naive precursors by CD40-activated B cells. Blood 112(6), pp. 2554-62, 09-2008. [Document] [DOI] [Web of Science] [Pubmed] ok

Vince J.E., Chau D., Callus B., Wong W.W., Hawkins C.J., Schneider P., McKinlay M., Benetatos C.A., Condon S.M., Chunduru S.K. et al., TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. Journal of Cell Biology 182(1), pp. 171-184, 2008. [Document] [DOI] [Web of Science] [Pubmed] ok


Casal M.L., Lewis J.R., Mauldin E.A., Tardivel A., Ingold K., Favre M., Paradies F., Demotz S., Gaide O., Schneider P., Significant correction of disease after postnatal administration of recombinant ectodysplasin A in canine X-linked ectodermal dysplasia. American Journal of Human Genetics 81(5), pp. 1050-1056, 2007. [Document] [DOI] [Web of Science] [Pubmed]

Kothlow S., Morgenroth I., Graef Y., Schneider K., Riehl I., Staeheli P., Schneider P., Kaspers B., Unique and conserved functions of B cell-activating factor of the TNF family (BAFF) in the chicken. International Immunology 19(2), pp. 203-215, 2007. [Document] [DOI] [Web of Science] [Pubmed]

Kummer J.A., Micheau O., Schneider P., Bovenschen N., Broekhuizen R., Quadir R., Strik M.C., Hack C.E., Tschopp J., Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis. Cell Death and Differentiation 14(8), pp. 1486-1496, 2007. [Document] [DOI] [Web of Science] [Pubmed]

Pummila M., Fliniaux I., Jaatinen R., James M.J., Laurikkala J., Schneider P., Thesleff I., Mikkola M.L., Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development 134(1), pp. 117-125, 2007. [Document] [DOI] [Web of Science] [Pubmed] ok

Schwaller J., Schneider P., Mhawech-Fauceglia P., McKee T., Myit S., Matthes T., Tschopp J., Donze O., Le Gal F.A., Huard B., Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness. Blood 109(1), pp. 331-338, 2007. [Document] [DOI] [Web of Science] [Pubmed] ok

Vince J.E., Wong W.W., Khan N., Feltham R., Chau D., Ahmed A.U., Benetatos C.A., Chunduru S.K., Condon S.M., McKinlay M. et al., IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 131(4), pp. 682-693, 2007. [Document] [DOI] [Web of Science] [Pubmed]

Willett B.J., McMonagle E.L., Logan N., Spiller O.B., Schneider P., Hosie M.J., Probing the interaction between feline immunodeficiency virus and CD134 by using the novel monoclonal antibody 7D6 and the CD134 (Ox40) ligand. Journal of Virology 81(18), pp. 9665-9679, 2007. [Document] [DOI] [Web of Science] [Pubmed]


Bossen C., Ingold K., Tardivel A., Bodmer J.L., Gaide O., Hertig S., Ambrose C., Tschopp J., Schneider P., Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. Journal of Biological Chemistry 281(20), pp. 13964-13971, 2006. [Document] [DOI] [Web of Science] [Pubmed]

Bossen C., Schneider P., BAFF, APRIL and their receptors: structure, function and signaling. Seminars in Immunology 18(5), pp. 263-275, 2006. [Document] [DOI] [Web of Science] [Pubmed]

Cachero T.G., Schwartz I.M., Qian F., Day E.S., Bossen C., Ingold K., Tardivel A., Krushinskie D., Eldredge J., Silvian L. et al., Formation of virus-like clusters is an intrinsic property of the tumor necrosis factor family member BAFF (B cell activating factor). Biochemistry 45(7), pp. 2006-2013, 2006. [Document] [DOI] [Web of Science] [Pubmed]

Corazza N., Jakob S., Schaer C., Frese S., Keogh A., Stroka D., Kassahn D., Torgler R., Mueller C., Schneider P. et al., TRAIL receptor-mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality. Journal of Clinical Investigation 116(9), pp. 2493-2499, 2006. [Document] [DOI] [Web of Science] [Pubmed] ok

Farley S.M., Dotson A.D., Purdy D.E., Sundholm A.J., Schneider P., Magun B.E., Iordanov M.S., Fas ligand elicits a caspase-independent proinflammatory response in human keratinocytes: implications for dermatitis. Journal of Investigative Dermatology 126(11), pp. 2438-2451, 2006. [Document] [DOI] [Web of Science] [Pubmed] ok

Girgenrath M., Weng S., Kostek C.A., Browning B., Wang M., Brown S.A., Winkles J.A., Michaelson J.S., Allaire N., Schneider P. et al., TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. EMBO Journal 25(24), pp. 5826-5839, 2006. [Document] [DOI] [Web of Science] [Pubmed]

Mérino D., Lalaoui N., Morizot A., Schneider P., Solary E., Micheau O., Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Molecular and Cellular Biology 26(19), pp. 7046-7055, 2006. [Document] [DOI] [Web of Science] [Pubmed] ok

Mou C., Jackson B., Schneider P., Overbeek P.A., Headon D.J., Generation of the primary hair follicle pattern. Proceedings of the National Academy of Sciences of the United States of America 103(24), pp. 9075-9080, 2006. [Document] [DOI] [Web of Science] [Pubmed] ok

Schmidt-Ullrich R., Tobin D.J., Lenhard D., Schneider P., Paus R., Scheidereit C., NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth. Development 133(6), pp. 1045-1057, 2006. [Document] [DOI] [Web of Science] [Pubmed]


Cebecauer M., Guillaume P., Hozák P., Mark S., Everett H., Schneider P., Luescher I.F., Soluble MHC-peptide complexes induce rapid death of CD8+ CTL. Journal of immunology 174(11), pp. 6809-6819, 2005. [Document] [Web of Science] [Pubmed] ok

Fournel S., Wieckowski S., Sun W., Trouche N., Dumortier H., Bianco A., Chaloin O., Habib M., Peter J.C., Schneider P. et al., C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L. Nature Chemical Biology 1(7), pp. 377-382, 2005. [Document] [DOI] [Web of Science] [Pubmed]

Ingold K., Zumsteg A., Tardivel A., Huard B., Steiner Q.G., Cachero T.G., Qiang F., Gorelik L., Kalled S.L., Acha-Orbea H. et al., Identification of proteoglycans as the APRIL-specific binding partners. Journal of Experimental Medicine 201(9), pp. 1375-1383, 2005. [Document] [DOI] [Web of Science] [Pubmed]

Iordanov M.S., Ryabinina O.P., Schneider P., Magun B.E., Two mechanisms of caspase 9 processing in double-stranded RNA- and virus-triggered apoptosis. Apoptosis 10(1), pp. 153-166, 2005. [Document] [DOI] [Web of Science] [Pubmed]

Iordanov M.S., Sundholm A.J., Simpson E.L., Hanifin J.M., Ryabinina O.P., Choi R.J., Korcheva V.B., Schneider P., Magun B.E., Cell death-induced activation of epidermal growth factor receptor in keratinocytes: implications for restricting epidermal damage in dermatitis. Journal of Investigative Dermatology 125(1), pp. 134-142, 2005. [Document] [DOI] [Web of Science] [Pubmed]

Kvell K., Nguyen T.H., Salmon P., Glauser F., Werner-Favre C., Barnet M., Schneider P., Trono D., Zubler R.H., Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors. Molecular Therapy 12(5), pp. 892-899, 2005. [Document] [DOI] [Web of Science] [Pubmed]

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