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101 publications

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Autologous Cell Therapy Approach for Duchenne Muscular Dystrophy using PiggyBac Transposons and Mesoangioblasts.
Iyer P.S., Mavoungou L.O., Ronzoni F., Zemla J., Schmid-Siegert E., Antonini S., Neff L.A., Dorchies O.M., Jaconi M., Lekka M. et al., 2018/04/04. Molecular therapy, 26 (4) pp. 1093-1108. Peer-reviewed.
Automated microfluidic sorting of mammalian cells labeled with magnetic microparticles for those that efficiently express and secrete a protein of interest
Droz X., Harraghy N., Lançon E., Le Fourn V., Calabrese D., Colombet T., Liechti P., Rida A., Girod P.A., Mermod N., 2017. Biotechnology and Bioengineering, 114 (8) pp. 1791-1802. Peer-reviewed.
MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering.
Kostyrko K., Neuenschwander S., Junier T., Regamey A., Iseli C., Schmid-Siegert E., Bosshard S., Majocchi S., Le Fourn V., Girod P.A. et al., 2017. Biotechnology and Bioengineering, 114 (2) pp. 384-396. Peer-reviewed.
Assays for DNA double-strand break repair by microhomology-based end-joining repair mechanisms.
Kostyrko K., Mermod N., 2016. Nucleic Acids Research, 44 (6) pp. e56. Peer-reviewed.
Development of a candidate reference material for adventitious virus detection in vaccine and biologicals manufacturing by deep sequencing.
Mee E.T., Preston M.D., Minor P.D., Schepelmann S., CS533 Study Participants, 2016. Vaccine, 34 (17) pp. 2035-2043.
Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2.
Bire S., Casteret S., Piégu B., Beauclair L., Moiré N., Arensbuger P., Bigot Y., 2016. PLoS Genetics, 12 (3) pp. e1005902. Peer-reviewed.
A role for homologous recombination proteins in cell cycle regulation.
Kostyrko K., Bosshard S., Urban Z., Mermod N., 2015. Cell Cycle, 14 (17) pp. 2853-2861.
A survey of transposable element classification systems--a call for a fundamental update to meet the challenge of their diversity and complexity.
Piégu B., Bire S., Arensburger P., Bigot Y., 2015. Molecular Phylogenetics and Evolution, 86 pp. 90-109.
Epigenetic regulatory elements: Recent advances in understanding their mode of action and use for recombinant protein production in mammalian cells.
Harraghy N., Calabrese D., Fisch I., Girod P.A., LeFourn V., Regamey A., Mermod N., 2015. Biotechnology Journal, 10 (7) pp. 967-978.
MAR-Mediated Dystrophin Expression in Mesoangioblasts for Duchenne Muscular Dystrophy Cell Therapy
van Zwieten R.W., Iyer P., Majocchi S., Dusserre Y., Puttini S., Tedesco F.S., Cossu G, Mermod N., 2015. Molecular Biology, 04 (03) p. 134.
Nuclear Factor I-C acts as a regulator of hepatocyte proliferation at the onset of liver regeneration.
Edelmann S., Fahrner R., Malinka T., Song B.H., Stroka D., Mermod N., 2015. Liver International, 35 (4) pp. 1185-1194.
A PiggyBac-mediated approach for muscle gene transfer or cell therapy.
Ley D., Van Zwieten R., Puttini S., Iyer P., Cochard A., Mermod N., 2014. Stem Cell Research, 13 (3 Pt A) pp. 390-403.
CHO cell engineering to prevent polypeptide aggregation and improve therapeutic protein secretion.
Le Fourn V., Girod P.A., Buceta M., Regamey A., Mermod N., 2014. Metabolic Engineering, 21 pp. 91-102.
Epigenetic regulatory elements associate with specific histone modifications to prevent silencing of telomeric genes.
Majocchi S., Aritonovska E., Mermod N., 2014. Nucleic Acids Research, 42 (1) pp. 193-204.
Extracellular deposition of matrilin-2 controls the timing of the myogenic program during muscle regeneration.
Deák F., Mátés L., Korpos E., Zvara A., Szénási T., Kiricsi M., Mendler L., Keller-Pintér A., Ozsvári B., Juhász H. et al., 2014. Journal of Cell Science, 127 (Pt 15) pp. 3240-3256.
Gene expression changes in chronic inflammatory demyelinating polyneuropathy skin biopsies.
Puttini S., Panaite P.A., Mermod N., Renaud S., Steck A.J., Kuntzer T., 2014. Journal of Neuroimmunology, 270 (1-2) pp. 61-66. Peer-reviewed.
High Expression of hTERT and Stemness Genes in BORIS/CTCFL Positive Cells Isolated from Embryonic Cancer Cells.
Alberti L., Renaud S., Losi L., Leyvraz S., Benhattar J., 2014. PLoS One, 9 (10) pp. e109921.
Exogenous mRNA delivery and bioavailability in gene transfer mediated by piggyBac transposition.
Bire S., Gosset D., Jégot G., Midoux P., Pichon C., Rouleux-Bonnin F., 2013. BMC Biotechnology, 13 p. 75.
IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering.
Contie M., Leger O., Fouque N., Poitevin Y., Kosco-Vilbois M., Mermod N., Elson G., 2013. Biotechnology and Bioengineering, 110 (4) pp. 1153-1163.
MAR elements and transposons for improved transgene integration and expression.
Ley D., Harraghy N., Le Fourn V., Bire S., Girod P.A., Regamey A., Rouleux-Bonnin F., Bigot Y., Mermod N., 2013. PLoS One, 8 (4) pp. e62784.
MAR-mediated integration of plasmid vectors for in vivo gene transfer and regulation.
Puttini S., van Zwieten R.W., Saugy D., Lekka M., Hogger F., Ley D., Kulik A.J., Mermod N., 2013. BMC Molecular Biology, 14 p. 26.
Molecular characterization of a human matrix attachment region epigenetic regulator.
Arope S., Harraghy N., Pjanic M., Mermod N., 2013. PLoS One, 8 (11) pp. e79262.
Nuclear Factor I genomic binding associates with chromatin boundaries.
Pjanic M., Schmid C.D., Gaussin A., Ambrosini G., Adamcik J., Pjanic P., Plasari G., Kerschgens J., Dietler G., Bucher P. et al., 2013. BMC Genomics, 14 p. 99.
Optimization of the piggyBac Transposon Using mRNA and Insulators: Toward a More Reliable Gene Delivery System.
Bire S., Ley D., Casteret S., Mermod N., Bigot Y., Rouleux-Bonnin F., 2013. PLoS One, 8 (12) pp. e82559.
Transposase concentration controls transposition activity: myth or reality?
Bire S., Casteret S., Arnaoty A., Piégu B., Lecomte T., Bigot Y., 2013. Gene, 530 (2) pp. 165-171.
CTF/NF1 transcription factors act as potent genetic insulators for integrating gene transfer vectors.
Gaussin A., Modlich U., Bauche C., Niederländer N.J., Schambach A., Duros C., Artus A., Baum C., Cohen-Haguenauer O., Mermod N., 2012. Gene Therapy, 19 (1) pp. 15-24.
In situ evaluation of single-cell lysis by cytosol extraction observation through fluorescence decay and dielectrophoretic trapping time
Mernier G., Majocchi S., Mermod N., Renaud P., 2012. Sensors and Actuators B-Chemical, 166 pp. 907-912.
Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin.
Brunner J.M., Plattet P., Doucey M.A., Rosso L., Curie T., Montagner A., Wittek R., Vandelvelde M., Zurbriggen A., Hirling H. et al., 2012. PLoS One, 7 (3) pp. e32803.
Using matrix attachment regions to improve recombinant protein production.
Harraghy N., Buceta M., Regamey A., Girod P.A., Mermod N., 2012. Methods in Molecular Biology, 801 pp. 93-110.
BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells.
Renaud S., Loukinov D., Alberti L., Vostrov A., Kwon Y.W., Bosman F.T., Lobanenkov V., Benhattar J., 2011. Nucleic Acids Research, 39 (3) pp. 862-873.
Identification of a potent MAR element from the mouse genome and assessment of its activity in stable and transient transfections.
Harraghy N., Regamey A., Girod P.A., Mermod N., 2011. Journal of Biotechnology, 154 (1) pp. 11-20.
Nuclear factor I revealed as family of promoter binding transcription activators.
Pjanic M., Pjanic P., Schmid C., Ambrosini G., Gaussin A., Plasari G., Mazza C., Bucher P., Mermod N., 2011. BMC Genomics, 12 p. 181.
Protein-Binding Microarray Analysis of Tumor Suppressor AP2α Target Gene Specificity.
Kerschgens J., Renaud S., Schütz F., Grasso L., Egener-Kuhn T., Delaloye J.F., Lehr H.A., Vogel H., Mermod N., 2011. Plos One, 6 (8) pp. e22895.
Use of human MAR elements to improve retroviral vector production.
Buceta M., Galbete J.L., Kostic C., Arsenijevic Y., Mermod N., 2011. Gene Therapy, 18 (1) pp. 7-13. Peer-reviewed.
Nuclear factor I-C regulates TGF-{beta}-dependent hair follicle cycling.
Plasari G., Edelmann S., Högger F., Dusserre Y., Mermod N., Calabrese A., 2010. Journal of Biological Chemistry, 285 (44) pp. 34115-34125. Peer-reviewed.
Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data.
Ruijter J.M., Ramakers C., Hoogaars W.M., Karlen Y., Bakker O., van den Hoff M.J., Moorman A.F., 2009. Nucleic Acids Research, 37 (6) pp. e45. Peer-reviewed.
Avoiding epigenetic variations in transgene expression with genetic insulators
Gaussin A., Duros C., Artus A., Auclair C., Cohen-Haguenauer O., Mermod N., 2009., Abstracts, Combined Meeting 2009, November 20-25, 2009, Hannover, Germany, Convention Center at Hannover Fairground XVIIth Annual Congress of the European Society of Gene and Cell Therapy, 16th Annual Meeting of the German Society of Gene Therapy, 4th Annual Congress of the German Society for Stem Cell Research, Co-organized by the European Branch of the International Society for Cellular Therapy pp. 1506-1506 dans ESGCT, DGGT, GSZ, and ISCT 2009 Poster Presentations, Human Gene Therapy. Peer-reviewed.
Characterization of insulators and barrier elements for gene therapy
Mermod N., 2009., Abstracts 8th Annual Meeting French Society of Cell and Gene Therapy, 21-23 June 2009, Faculté de Médecine de la Pitié-Salpêtrière, Paris, France pp. 658-658 dans SFTCG 2009 Invited Presentations, Human Gene Therapy. Peer-reviewed.
Chromatin insulators and Prospective Application for gene Therapy.
Gaussin A., Mermod N., 2009. Gene Therapy Review pp. on line.
Diagnosis of muscular dystrophies at the nanometer scale
Puttini S., Lekka M., Kuntzer T., Mermod N., Kulik A., 2009. pp. 544-545 dans 14th International Congress of the World Muscle Society, Neuromuscular Disorders. Peer-reviewed.
Directed integration of new insulated lentiviral vectors to heterochromatin towards safer gene transfer to stem cells
Artus A., Duros C., Botbol Y., Gaussin A., Mermod N., Lavigne M., Cohen-Haguenauer O., 2009., Abstracts, Combined Meeting 2009, November 20-25, 2009, Hannover, Germany, Convention Center at Hannover Fairground XVIIth Annual Congress of the European Society of Gene and Cell Therapy, 16th Annual Meeting of the German Society of Gene Therapy, 4th Annual Congress of the German Society for Stem Cell Research, Co-organized by the European Branch of the International Society for Cellular Therapy pp. 1502-1502 dans ESGCT, DGGT, GSZ, and ISCT 2009 Poster Presentations, Human Gene Therapy. Peer-reviewed.
Gene-mediated restoration of normal myofiber elasticity in dystrophic muscles.
Puttini S., Lekka M., Dorchies O.M., Saugy D., Incitti T., Ruegg U.T., Bozzoni I., Kulik A.J., Mermod N., 2009. Molecular Therapy, 17 (1) pp. 19-25.
Insulated retroviral vectors towards safe and efficient genetic modification of stem cells
Duros C., Artus A., Auclair C., Gaussin A., Mermod N., Arock M., Schmidt M., Von Kalle C., Cohen-Haguenauer O. Y., 2009., Abstracts 8th Annual Meeting French Society of Cell and Gene Therapy, 21-23 June 2009, Faculté de Médecine de la Pitié-Salpêtrière ? Paris, France pp. 666-666 dans SFTCG 2009 Oral Presentations, Human Gene Therapy. Peer-reviewed.
Intracellular nanomanipulation by a photonic-force microscope with real-time acquisition of a 3D stiffness matrix.
Bertseva E., Singh A.S., Lekki J., Thévenaz P., Lekka M., Jeney S., Gremaud G., Puttini S., Nowak W., Dietler G. et al., 2009. Nanotechnology, 20 (28) p. 285709.
MAR elements regulate the probability of epigenetic switching between active and inactive gene expression.
Galbete J.L., Buceta M., Mermod N., 2009. Molecular BioSystems, 5 (2) pp. 143-150.
Mutations in NR2E3 can cause dominant or recessive retinal degenerations in the same family.
Escher P., Gouras P., Roduit R., Tiab L., Bolay S., Delarive T., Chen S., Tsai C.C., Hayashi M., Zernant J. et al., 2009. Human Mutation, 30 (3) pp. 342-351. Peer-reviewed.
Novel insulated gamma and lentis retroviral vectors towards safer genetic modification of stem cells
Duros C., Artus A., Gaussin A., Scholtz S., Mermod N., Schmidt M., von Kalle C., Cohen-Haguenauer O., 2009., Abstracts, Combined Meeting 2009, November 20-25, 2009, Hannover, Germany, Convention Center at Hannover Fairground XVIIth Annual Congress of the European Society of Gene and Cell Therapy, 16th Annual Meeting of the German Society of Gene Therapy, 4th Annual Congress of the German Society for Stem Cell Research, Co-organized by the European Branch of the International Society for Cellular Therapy pp. 1505-1505 dans ESGCT, DGGT, GSZ, and ISCT 2009 Poster Presentations, Human Gene Therapy. Peer-reviewed.
Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression.
Plasari G., Calabrese A., Dusserre Y., Gronostajski R.M., McNair A., Michalik L., Mermod N., 2009. Molecular and Cellular Biology, 29 (22) pp. 6006-6017. Peer-reviewed.
Protein-binding microarrays: probing disease markers at the interface of proteomics and genomics.
Kerschgens J., Egener-Kuhn T., Mermod N., 2009. Trends in Molecular Medicine, 15 (8) pp. 352-358.
Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.
Colland F., Formstecher E., Jacq X., Reverdy C., Planquette C., Conrath S., Trouplin V., Bianchi J., Aushev V.N., Camonis J. et al., 2009. Molecular Cancer Therapeutics, 8 (8) pp. 2286-2295.
Stochastic models and numerical algorithms for a class of regulatory gene networks.
Fournier T., Gabriel J.P., Pasquier J., Mazza C., Galbete J., Mermod N., 2009. Bulletin of Mathematical Biology, 71 (6) pp. 1394-1431.
Transcription factor CTF1 acts as a chromatin domain boundary that shields human telomeric genes from silencing.
Esnault G., Majocchi S., Martinet D., Besuchet-Schmutz N., Beckmann J.S., Mermod N., 2009. Molecular and Cellular Biology, 29 (9) pp. 2409-2418. Peer-reviewed.
Use of MAR elements to increase the production of recombinant proteins.
Gorman C., Arope S., Grandjean M., Girod P.-A., Mermod N., 2009. pp. 1-32 dans Al-Rubeai M. (eds.) Cell Line Development, Springer.
A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation.
Buceta M., Domínguez E., Castro M., Brea J., Alvarez D., Barcala J., Valdés L., Alvarez-Calderón P., Domínguez F., Vidal B. et al., 2008. Biochemical Pharmacology, 76 (7) pp. 912-921. Peer-reviewed.
Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes.
Harraghy N., Homerova D., Herrmann M., Kormanec J., 2008. Journal of Bacteriology, 190 (1) pp. 447-451. Peer-reviewed.
Sustained transgene expression using MAR elements.
Harraghy N., Gaussin A., Mermod N., 2008. Current Gene Therapy, 8 (5) pp. 353-366.
Signal peptide and helical bundle domains of virulent canine distemper virus fusion protein restrict fusogenicity.
Plattet P., Cherpillod P., Wiener D., Zipperle L., Vandevelde M., Wittek R., Zurbriggen A., 2007/10. Journal of Virology, 81 (20) pp. 11413-11425.
Steady-state expression of self-regulated genes.
Fournier T., Gabriel J.P., Mazza C., Pasquier J., Galbete J.L., Mermod N., 2007/10. Bioinformatics, 23 (23) pp. 3185-3192.
Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells.
Girod P.A., Nguyen D.Q., Calabrese D., Puttini S., Grandjean M., Martinet D., Regamey A., Saugy D., Beckmann J.S., Bucher P. et al., 2007/09. Nature Methods, 4 (9) pp. 747-753.
Adaptation of canine distemper virus to canine footpad keratinocytes modifies polymerase activity and fusogenicity through amino acid substitutions in the P/V/C and H proteins.
Rivals J.P., Plattet P., Currat-Zweifel C., Zurbriggen A., Wittek R., 2007/03. Virology, 359 (1) pp. 6-18.
Canine distemper virus infection of primary hippocampal cells induces increase in extracellular glutamate and neurodegeneration.
Brunner J.M., Plattet P., Majcherczyk P., Zurbriggen A., Wittek R., Hirling H., 2007. Journal of Neurochemistry, 103 (3) pp. 1184-1195.
Genetic insulators and epigenetic variations in gene expression and regulation
Gaussin A., Esnault G., Mermod N., 2007. pp. 989-989 dans 15th Annual Congress of the European Society of Gene and Cell Therapy, Human Gene Therapy. Peer-reviewed.
Quorum-sensing systems in staphylococci as therapeutic targets.
Harraghy N., Kerdudou S., Herrmann M., 2007. Analytical and Bioanalytical Chemistry, 387 (2) pp. 437-444.
Statistical significance of quantitative PCR.
Karlen Y., McNair A., Perseguers S., Mazza C., Mermod N., 2007. Bmc Bioinformatics, 8 p. 131.
Vaccinia immune globulin: current policies, preparedness, and product safety and efficacy.
Wittek R., 2006/05. International Journal of Infectious Diseases, 10 (3) pp. 193-201.
Identification of peptide ligands to the chemokine receptor CCR5 and their maturation by gene shuffling.
Vyroubalova E.C., Hartley O., Mermod N., Fisch I., 2006/04. Molecular Immunology, 43 (10) pp. 1573-1578.
Fast generation of high producer cho cell lines by an iterative transfection process
Girod P.A., Grandjean M., Calabrese D., Martinet D., Beckmann J., Mermod N., 2006. pp. S41 dans 4th Recombinant Protein Production Meeting, Microbial Cell Factories. Peer-reviewed.
The fusion protein of wild-type canine distemper virus is a major determinant of persistent infection.
Plattet P., Rivals J.P., Zuber B., Brunner J.M., Zurbriggen A., Wittek R., 2005/07. Virology, 337 (2) pp. 312-326.
Use of the chicken lysozyme 5' matrix attachment region to generate high producer CHO cell lines.
Girod P.A., Zahn-Zabal M., Mermod N., 2005/07. Biotechnology and Bioengineering, 91 (1) pp. 1-11.
Large-scale analysis of 73 329 physcomitrella plants transformed with different gene disruption libraries: production parameters and mutant phenotypes.
Schween G., Egener T., Fritzowsky D., Granado J., Guitton M.C., Hartmann N., Hohe A., Holtorf H., Lang D., Lucht J.M. et al., 2005. Plant Biology, 7 (3) pp. 228-237. Peer-reviewed.
MAR elements as tools to increase protein production by CHO cells
Girod P.A., Zahn-Zabal M.M., Mermod N., 2005., Proceedings of the 18th ESACT Meeting Granada, Spain, May 11-14, 2003 pp. 411-415 dans Gòdia F., Fussenegger M. (eds.) Animal Cell Technology Meets Genomics., ESACT Proceedings, Springer.
Proof of concept for microarray-based detection of DNA-binding oncogenes in cell extracts.
Egener T., Roulet E., Zehnder M., Bucher P., Mermod N., 2005. Nucleic Acids Research, 33 (8) pp. e79.
Reversal of the silencing of tetracycline-controlled genes requires the coordinate action of distinctly acting transcription factors.
Pankiewicz R., Karlen Y., Imhof M.O., Mermod N., 2005/01. Journal of Gene Medicine, 7 (1) pp. 117-132.
Structure-function characterization and optimization of a plant-derived antibacterial peptide.
Suarez M., Haenni M., Canarelli S., Fisch F., Chodanowski P., Servis C., Michielin O., Freitag R., Moreillon P., Mermod N., 2005. Antimicrobial Agents and Chemotherapy, 49 (9) pp. 3847-3857.
Chromatin domain boundaries delimited by a histone-binding protein in yeast.
Ferrari S., Simmen K.C., Dusserre Y., Müller K., Fourel G., Gilson E., Mermod N., 2004/12. Journal of Biological Chemistry, 279 (53) pp. 55520-55530.
An mRNA region of the canine distemper virus fusion protein gene lacking AUG codons can promote protein expression.
Cherpillod P., Zipperle L., Wittek R., Zurbriggen A., 2004/10. Archives of Virology, 149 (10) pp. 1971-1983.
Could smallpox come back?
Wittek R., 2004/10. International Journal of Infectious Diseases, 8 Suppl 2 pp. S1.
Recovery of a persistent Canine distemper virus expressing the enhanced green fluorescent protein from cloned cDNA.
Plattet P., Zweifel C., Wiederkehr C., Belloy L., Cherpillod P., Zurbriggen A., Wittek R., 2004/05. Virus Research, 101 (2) pp. 147-153.
Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.
Tan N.S., Michalik L., Di-Poï N., Ng C.Y., Mermod N., Roberts A.B., Desvergne B., Wahli W., 2004. EMBO Journal, 23 (21) pp. 4211-4221. Peer-reviewed.
Transcriptional activation of the utrophin promoter B by a constitutively active Ets-transcription factor.
Briguet A., Bleckmann D., Bettan M., Mermod N., Meier T., 2003/02. Neuromuscular Disorders, 13 (2) pp. 143-150.
Expression of a plant-derived peptide harboring water-cleaning and antimicrobial activities.
Suarez M., Entenza J.M., Doerries C., Meyer E., Bourquin L., Sutherland J., Marison I., Moreillon P., Mermod N., 2003. Biotechnology and Bioengineering, 81 (1) pp. 13-20.
Use of scaffold/matrix-attachment regions for protein production
Girod P. A., Mermod N., 2003. pp. 359-379 dans Makrides S.C. (eds.) Gene transfer and expression in mammalian cells, Elsevier.
Comparative study and identification of potent eukaryotic transcriptional repressors in gene switch systems.
Imhof M.O., Chatellard P., Mermod N., 2002. Journal of Biotechnology, 97 (3) pp. 275-285.
Gene transfer : The ins, the outs... and the next generation.
Mermod N., Cornetta K.G., 2002. Current Opinion in Biotechnology, 13 (5) pp. 415-417. Peer-reviewed.
High-throughput SELEX SAGE method for quantitative modeling of transcription-factor binding sites.
Roulet E., Busso S., Camargo A.A., Simpson A.J., Mermod N., Bucher P., 2002. Nature Biotechnology, 20 (8) pp. 831-835.
Development of stable cell lines for production or regulated expression using matrix attachment regions.
Zahn-Zabal M., Kobr M., Girod P.A., Imhof M., Chatellard P., de Jesus M., Wurm F., Mermod N., 2001/04. Journal of Biotechnology, 87 (1) pp. 29-42.
An activation-independent role of transcription factors in insulator function.
Fourel G., Boscheron C., Revardel E., Lebrun E., Hu Y.F., Simmen K.C., Müller K., Li R., Mermod N., Gilson E., 2001/02. EMBO Reports, 2 (2) pp. 124-132.
Upregulation of vasopressin V1A receptor mRNA and protein in vascular smooth muscle cells following cyclosporin A treatment.
Cottet-Maire F., Avdonin P.V., Roulet E., Buetler T.M., Mermod N., Ruegg U.T., 2001/02. British Journal of Pharmacology, 132 (4) pp. 909-917.
A regulatory network for the efficient control of transgene expression.
Imhof M.O., Chatellard P., Mermod N., 2000. The Journal of Gene Medicine, 2 (2) pp. 107-116.
CHO expression of a novel human recombinant IgG1 anti-RhD antibody isolated by phage display.
Miescher S., Zahn-Zabal M., De Jesus M., Moudry R., Fisch I., Vogel M., Kobr M., Imboden M.A., Kragten E., Bichler J. et al., 2000. British Journal of Haematology, 111 (1) pp. 157-166.
Experimental analysis and computer prediction of CTF/NFI transcription factor DNA binding sites.
Roulet E., Bucher P., Schneider R., Wingender E., Dusserre Y., Werner T., Mermod N., 2000. Journal of Molecular Biology, 297 (4) pp. 833-848.
The histone-interacting domain of nuclear factor I activates simian virus 40 DNA replication in vivo.
Müller K., Mermod N., 2000. Journal of Biological Chemistry, 275 (3) pp. 1645-1650.
An autoregulatory loop controlling CYP1A1 gene expression: role of H(2)O(2) and NFI.
Morel Y., Mermod N., Barouki R., 1999. Molecular and Cellular Biology, 19 (10) pp. 6825-6832.
Biotechnology in Lausanne: the Rh D project.
Von Stockar U., Kragten E., Marison I.W., Amstutz H., Miescher S., Fisch I., Mermod N., DeJesus M., Freitag R., Wurm F., 1999. Chimia, 53 (11) pp. 554-557. Peer-reviewed.
Matrix attachment regions in stable CHO cell line development.
Zahn, M., , Kobr M., Mermod N, 1999. pp. 79-81 dans Bernard A., Griffiths B., Noé W., Wurm F. (eds.) Animal cell technology: products from cells, cells as products, Kluwer.
The SPP Biotech Module 1: Proteins for medical applications. A multidisciplinary effort for the development of a recombinant anti-RHD antibody preparation for the prevention of the hemolytic disease of the newborn.
Amstutz H., Miescher S., Moudry R., Desjardin S., Imboden M., Morgenthaler J.J., Zahn M., Kobr M., Fisch I., Corthésy B. et al., 1999., Proceedings of the 16th ESACT Meeting, April 25-29, 1999, Lugano, Switzerland pp. 455-458 dans Bernard A., Griffiths B., Noé W., Wurm F. (eds.) Animal cell technology: products from cells, cells as products, Kluwer Academic Publishing.
Evaluation of computer tools for the prediction of transcription factor binding sites on genomic DNA.
Roulet E., Fisch I., Junier T., Bucher P., Mermod N., 1998. In Silico Biology, 1 (1) pp. 21-28.
Micro-patterning of biomolecules on polymer substrates.
Schwarz A., Rossier J.S., Roulet E., Mermod N., Roberts M.A., Girault H.H., 1998. Langmuir, 14 (19) pp. 5526-5531.
Transforming growth factor-beta: the breaking open of a black box.
Alevizopoulos A., Mermod N., 1997/07. Bioessays, 19 (7) pp. 581-591.
Regulation of the transforming growth factor beta-responsive transcription factor CTF-1 by calcineurin and calcium/calmodulin-dependent protein kinase IV.
Alevizopoulos A., Dusserre Y., Rüegg U., Mermod N., 1997. Journal of Biological Chemistry, 272 (38) pp. 23597-23605.
cis- and trans-acting elements involved in reactivation of vaccinia virus early transcription.
Masternak K., Wittek R., 1996. Journal of virology, 70 (12) pp. 8737-46. Peer-reviewed.
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