Département de pharmacologie et toxicologie

Equipe principale | Groupe Bonny | Groupe Broillet | Groupe Cotecchia | Groupe Diviani | Groupe Firsov | Groupe Hummler | Groupe Katanaev | Groupe Kellenberger | Groupe Ocampo | Groupe Rossier | Groupe Schild | Groupe Staub
Publications | Mémoires et thèses

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1276 publications

Sous presse | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | ...
Imatinib uptake into cells is not mediated by organic cation transporters OCT1, OCT2, or OCT3, but is influenced by extracellular pH.
Blanc Mettral J., Faller N., Cruchon S., Sottas L., Buclin T., Schild L., Choong E., Nahimana A., Decosterd L.A. Drug metabolism letters. Peer-reviewed.
The Anti-Malarial Drug Artesunate Attenuates Cardiac Injury in a Rodent Model of Myocardial Infarction.
Khan A.I., Kapoor A., Che J., Martin L., Rogazzo M., Mercier T., Decosterd L., Collino M., Thiemermann C. Shock. Peer-reviewed.
A molecular view of the function and pharmacology of acid-sensing ion channels.
Vullo S., Kellenberger S. Pharmacological research. Peer-reviewed.
The Role of Cyclic AMP Signaling in Cardiac Fibrosis.
Delaunay M., Osman H., Kaiser S., Diviani D., 2019/12/26. Cells, 9 (1). Peer-reviewed.
Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion.
Keppner A., Maric D., Sergi C., Ansermet C., De Bellis D., Kratschmar D.V., Canonica J., Klusonova P., Fenton R.A., Odermatt A. et al., 2019/12/20. Scientific reports, 9 (1) p. 19540. Peer-reviewed.
Associations of autozygosity with a broad range of human phenotypes.
Clark D.W., Okada Y., Moore KHS, Mason D., Pirastu N., Gandin I., Mattsson H., Barnes CLK, Lin K., Zhao J.H. et al., 2019/10/31. Nature communications, 10 (1) p. 4957. Peer-reviewed.
The role of A-kinase anchoring proteins in cardiac oxidative stress.
Diviani D., Osman H., Delaunay M., Kaiser S., 2019/10/31. Biochemical Society transactions, 47 (5) pp. 1341-1353. Peer-reviewed.
Mg<sup>2+</sup> restriction downregulates NCC through NEDD4-2 and prevents its activation by hypokalemia.
Ferdaus M.Z., Mukherjee A., Nelson J.W., Blatt P.J., Miller L.N., Terker A.S., Staub O., Lin D.H., McCormick J.A., 2019/10/01. American journal of physiology. Renal physiology, 317 (4) pp. F825-F838. Peer-reviewed.
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Burgener A.V., Bantug G.R., Meyer B.J., Higgins R., Ghosh A., Bignucolo O., Ma E.H., Loeliger J., Unterstab G., Geigges M. et al., 2019/10. Nature immunology, 20 (10) pp. 1311-1321. Peer-reviewed.
Stabilizing cumulative incidence estimation of pregnancy outcome with delayed entries.
Rousson V., Allignol A., Aurousseau A., Winterfeld U., Beyersmann J., 2019/09. Biometrical journal. Biometrische Zeitschrift, 61 (5) pp. 1290-1302. Peer-reviewed.
Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
Suzuki Keiichiro, Yamamoto Mako, Hernandez-Benitez Reyna, Li Zhe, Wei Christopher, Soligalla Rupa Devi, Aizawa Emi, Hatanaka Fumiyuki, Kurita Masakazu, Reddy Pradeep et al., 2019/08/23. Cell Research.
Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway
Hishida Tomoaki, Vazquez-Ferrer Eric, Hishida-Nozaki Yuriko, Sancho-Martinez Ignacio, Takahashi Yuta, Hatanaka Fumiyuki, Wu Jun, Ocampo Alejandro, Reddy Pradeep, Wu Min-Zu et al., 2019/07. Protein & Cell, 10 (7) pp. 485-495.
A model of uric acid transport in the rat proximal tubule.
Edwards A., Auberson M., Ramakrishnan S.K., Bonny O., 2019/05/01. American journal of physiology. Renal physiology, 316 (5) pp. F934-F947. Peer-reviewed.
Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitor.
Ahmed K., Koval A., Xu J., Bodmer A., Katanaev V.L., 2019/05/01. Cancer letters, 449 pp. 45-55. Peer-reviewed.
Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum.
Subramanian A., Capalbo A., Iyengar N.R., Rizzo R., di Campli A., Di Martino R., Lo Monte M., Beccari A.R., Yerudkar A., Del Vecchio C. et al., 2019/03/07. Cell, 176 (6) pp. 1461-1476.e23. Peer-reviewed.
Chemins de l’in(ter)disciplinarité: connaissance, corps, language
Benaroyo L., Berthoud A.-C., Diezi J., Merminod G., Papaux A., Schenk F., Usunier J.-C., Volken H., 2019/03. Sciences et enjeux, 10 216, L'Harmattan - Academia.
Mutations in the palm domain disrupt modulation of acid-sensing ion channel 1a currents by neuropeptides.
Bargeton B., Iwaszkiewicz J., Bonifacio G., Roy S., Zoete V., Kellenberger S., 2019/02/22. Scientific reports, 9 (1) p. 2599. Peer-reviewed.
Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics, cell autonomous feedback regulation, and a telocyte phenotype.
Imeri F., Nolan K.A., Bapst A.M., Santambrogio S., Abreu-Rodríguez I., Spielmann P., Pfundstein S., Libertini S., Crowther L., Orlando IMC et al., 2019/02. Kidney international, 95 (2) pp. 375-387. Peer-reviewed.
A high-throughput assay pipeline for specific targeting of frizzled GPCRs in cancer.
Shaw H.V., Koval A., Katanaev V.L., 2019. Methods in cell biology, 149 pp. 57-75. Peer-reviewed.
Accelerated Current Decay Kinetics of a Rare Human Acid-Sensing ion Channel 1a Variant That Is Used in Many Studies as Wild Type.
Vaithia A., Vullo S., Peng Z., Alijevic O., Kellenberger S., 2019. Frontiers in molecular neuroscience, 12 p. 133. Peer-reviewed.
Closed-loop Neuropharmacology for Epilepsy: Distant Dream or Future Reality?
Aicua-Rapun I., André P., Novy J., 2019. Current neuropharmacology, 17 (5) pp. 447-458. Peer-reviewed.
Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na<sup>+</sup>/Cl<sup>-</sup> Cotransporter NCC and Transiently Affects Sodium Handling.
Canonica J., Frateschi S., Boscardin E., Ebering A., Sergi C., Jäger Y., Peyrollaz T., Mérillat A.M., Maillard M., Klusonova P. et al., 2019. Frontiers in physiology, 10 p. 989. Peer-reviewed.
SLC2A9 (GLUT9) mediates urate reabsorption in the mouse kidney.
Auberson M., Stadelmann S., Stoudmann C., Seuwen K., Koesters R., Thorens B., Bonny O., 2018/12. Pflugers Archiv, 470 (12) pp. 1739-1751. Peer-reviewed.
Global Prevalence of Protein-Energy Wasting in Kidney Disease: A Meta-analysis of Contemporary Observational Studies From the International Society of Renal Nutrition and Metabolism.
Carrero J.J., Thomas F., Nagy K., Arogundade F., Avesani C.M., Chan M., Chmielewski M., Cordeiro A.C., Espinosa-Cuevas A., Fiaccadori E. et al., 2018/11. Journal of renal nutrition, 28 (6) pp. 380-392. Peer-reviewed.
Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts.
Koval A., Pieme C.A., Queiroz E.F., Ragusa S., Ahmed K., Blagodatski A., Wolfender J.L., Petrova T.V., Katanaev V.L., 2018/10/28. Cancer letters, 435 pp. 110-120. Peer-reviewed.
A model of calcium transport and regulation in the proximal tubule.
Edwards A., Bonny O., 2018/10/01. American journal of physiology. Renal physiology, 315 (4) pp. F942-F953. Peer-reviewed.
Circadian rhythms and the kidney.
Firsov D., Bonny O., 2018/10. Nature reviews. Nephrology, 14 (10) pp. 626-635. Peer-reviewed.
Kir5.1 regulates Nedd4-2-mediated ubiquitination of Kir4.1 in distal nephron.
Wang M.X., Su X.T., Wu P., Gao Z.X., Wang W.H., Staub O., Lin D.H., 2018/10/01. American journal of physiology. Renal physiology, 315 (4) pp. F986-F996. Peer-reviewed.
Sex Differences in Efficacy and Toxicity of Systemic Treatments: An Undervalued Issue in the Era of Precision Oncology.
Özdemir B.C., Csajka C., Dotto G.P., Wagner A.D., 2018/09/10. Journal of clinical oncology, 36 (26) pp. 2680-2683. Peer-reviewed.
In vivo reprogramming of wound-resident cells generates skin epithelial tissue
Kurita Masakazu, Araoka Toshikazu, Hishida Tomoaki, O'Keefe David D., Takahashi Yuta, Sakamoto Akihisa, Sakurai Masahiro, Suzuki Keiichiro, Wu Jun, Yamamoto Mako et al., 2018/09. Nature, 561 (7722) pp. 243-247.
Circadian variation of ticagrelor-induced platelet inhibition in healthy adulty.
Fournier S., Guenat F., Fournier A., Alberio L., Bonny O., Bertaggia Calderara D., Bardy D., Lauriers N., Harbaoui B., Monney P. et al., 2018/07/01. European heart journal. Cardiovascular pharmacotherapy, 4 (3) pp. 166-171. Peer-reviewed.
Redox-Dependent Bone Alkaline Phosphatase Dysfunction Drives Part of the Complex Bone Phenotype in Mice Deficient for <i>Memo1</i>.
Moor M.B., Ramakrishnan S.K., Legrand F., Dolder S., Siegrist M., Durussel F., Centeno G., Firsov D., Hynes N.E., Hofstetter W. et al., 2018/07. JBMR plus, 2 (4) pp. 195-205. Peer-reviewed.
Medicinal mushrooms as an attractive new source of natural compounds for future cancer therapy.
Blagodatski A., Yatsunskaya M., Mikhailova V., Tiasto V., Kagansky A., Katanaev V.L., 2018/06/26. Oncotarget, 9 (49) pp. 29259-29274. Peer-reviewed.
Heteroarylguanidines as Allosteric Modulators of ASIC1a and ASIC3 Channels.
Alijevic O., Hammoud H., Vaithia A., Trendafilov V., Bollenbach M., Schmitt M., Bihel F., Kellenberger S., 2018/06/20. ACS chemical neuroscience, 9 (6) pp. 1357-1365. Peer-reviewed.
The Role of Intercalated Cell Nedd4-2 in BP Regulation, Ion Transport, and Transporter Expression.
Nanami M., Pham T.D., Kim Y.H., Yang B., Sutliff R.L., Staub O., Klein J.D., Lopez-Cayuqueo K.I., Chambrey R., Park A.Y. et al., 2018/06. Journal of the American Society of Nephrology, 29 (6) pp. 1706-1719. Peer-reviewed.
Versatility of Turing patterns potentiates rapid evolution in tarsal attachment microstructures of stick and leaf insects (Phasmatodea).
Büscher T.H., Kryuchkov M., Katanaev V.L., Gorb S.N., 2018/06. Journal of the Royal Society, Interface, 15 (143) p. 1. Peer-reviewed.
Dramatic dysbalancing of the Wnt pathway in breast cancers.
Koval A., Katanaev V.L., 2018/05/09. Scientific reports, 8 (1) p. 7329. Peer-reviewed.
Gαo (GNAO1) encephalopathies: plasma membrane vs. Golgi functions.
Solis G.P., Katanaev V.L., 2018/05/08. Oncotarget, 9 (35) pp. 23846-23847. Peer-reviewed.
Antagonistic PCP Signaling Pathways in the developing Drosophila eye.
Katanaev V.L., Egger-Adam D., Tomlinson A., 2018/04/10. Scientific reports, 8 (1) p. 5741. Peer-reviewed.
Quantitative Analysis of Gentamicin Exposure in Neonates and Infants Calls into Question Its Current Dosing Recommendations.
van Donge T., Pfister M., Bielicki J., Csajka C., Rodieux F., van den Anker J., Fuchs A., 2018/04. Antimicrobial agents and chemotherapy, 62 (4) pp. e02004-17 . Peer-reviewed.
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Vigolo M., Chambers M.G., Willen L., Chevalley D., Maskos K., Lammens A., Tardivel A., Das D., Kowalczyk-Quintas C., Schuepbach-Mallepell S. et al., 2018/03/23. Nature communications, 9 (1) p. 1199. Peer-reviewed.
Author Correction: The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.
Rosenbaek L.L., Rizzo F., Wu Q., Rojas-Vega L., Gamba G., MacAulay N., Staub O., Fenton R.A., 2018/03/06..
Plasma Potassium Determines NCC Abundance in Adult Kidney-Specific γENaC Knockout.
Boscardin E., Perrier R., Sergi C., Maillard M.P., Loffing J., Loffing-Cueni D., Koesters R., Rossier B.C., Hummler E., 2018/03. Journal of the American Society of Nephrology, 29 (3) pp. 977-990. Peer-reviewed.
High capacity in G protein-coupled receptor signaling.
Keshelava A., Solis G.P., Hersch M., Koval A., Kryuchkov M., Bergmann S., Katanaev V.L., 2018/02/28. Nature communications, 9 (1) p. 876. Peer-reviewed.
A-Kinase Anchoring Protein-Lbc: A Molecular Scaffold Involved in Cardiac Protection.
Diviani D., Osman H., Reggi E., 2018/02/08. Journal of cardiovascular development and disease, 5 (1). Peer-reviewed.
Exploiting Pharmacokinetic Models of Tamoxifen and Endoxifen to Identify Factors Causing Subtherapeutic Concentrations in Breast Cancer Patients.
Klopp-Schulze L., Joerger M., Wicha S.G., Ter Heine R., Csajka C., Parra-Guillen Z.P., Kloft C., 2018/02. Clinical pharmacokinetics, 57 (2) pp. 229-242. Peer-reviewed.
Rapid Remission of Graves' Hyperthyroidism Without Thionamides Under Immunosuppressive Treatment for Concomitant Autoimmune Hepatitis.
Papadakis G.E., Lamine F., Chtioui H., Moschouri E., Christinet M.F., Marino L., Favre L., Sciarra A., Sempoux C., Schneider A. et al., 2018/02. Thyroid, 28 (2) pp. 276-278. Peer-reviewed.
Alarm pheromone and kairomone detection via bitter taste receptors in the mouse Grueneberg ganglion.
Moine F., Brechbühl J., Nenniger Tosato M., Beaumann M., Broillet M.C., 2018/01/18. BMC biology, 16 (1) p. 12. Peer-reviewed.
Pharmacovigilance [Pharmacovigilance update]
Livio F., 2018/01/10. Revue medicale suisse, 14 (588-589) pp. 81-84. Peer-reviewed.
Human Mutations in SLC2A9 (Glut9) Affect Transport Capacity for Urate.
Ruiz A., Gautschi I., Schild L., Bonny O., 2018. Frontiers in physiology, 9 p. 476. Peer-reviewed.
Renal Memo1 Differentially Regulates the Expression of Vitamin D-Dependent Distal Renal Tubular Calcium Transporters.
Moor M.B., Haenzi B., Legrand F., Koesters R., Hynes N.E., Bonny O., 2018. Frontiers in physiology, 9 p. 874. Peer-reviewed.
A population-based approach to assess the heritability and distribution of renal handling of electrolytes.
Moulin F., Ponte B., Pruijm M., Ackermann D., Bouatou Y., Guessous I., Ehret G., Bonny O., Pechère-Bertschi A., Staessen J.A. et al., 2017/12. Kidney international, 92 (6) pp. 1536-1543. Peer-reviewed.
OATP1B1 and DAA treatment for hepatitis C in patients with hepatocellular carcinoma.
Chtioui H., 2017/12. Hepatology, 66 (6) p. 2091. Peer-reviewed.
Pharmacist intervention acceptance for the reduction of potentially inappropriate drug prescribing in acute psychiatry.
Hannou S., Voirol P., Pannatier A., Weibel M.L., Sadeghipour F., von Gunten A., Mall J.F., De Giorgi Salamun I., 2017/12. International journal of clinical pharmacy, 39 (6) pp. 1228-1236. Peer-reviewed.
Alexander S.P., Kelly E., Marrion N.V., Peters J.A., Faccenda E., Harding S.D., Pawson A.J., Sharman J.L., Southan C., Buneman O.P. et al., 2017/12. British journal of pharmacology, 174 Suppl 1 pp. S1-S16. Peer-reviewed.
Détecter et évaluer l’impact desmédicaments anticholinergiques [Detecting and assessing the impactof anticholinergic medications]
Csajka C., Brémond C., Lang P.O., 2017/11/08. Revue medicale suisse, 13 (582) pp. 1931-1937. Peer-reviewed.
The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation.
Rosenbaek L.L., Rizzo F., Wu Q., Rojas-Vega L., Gamba G., MacAulay N., Staub O., Fenton R.A., 2017/10/11. Scientific reports, 7 (1) p. 12981. Peer-reviewed.
Severe hyperkalemia is rescued by low-potassium diet in renal βENaC-deficient mice.
Boscardin E., Perrier R., Sergi C., Maillard M., Loffing J., Loffing-Cueni D., Koesters R., Rossier B.C., Hummler E., 2017/10. Pflugers Archiv, 469 (10) pp. 1387-1399. Peer-reviewed.
High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle stars.
Blagodatski A., Cherepanov V., Koval A., Kharlamenko V.I., Khotimchenko Y.S., Katanaev V.L., 2017/09/20. Scientific reports, 7 (1) p. 11964. Peer-reviewed.
The genomic landscape of human cellular circadian variation points to a novel role for the signalosome.
Gaspar L., Howald C., Popadin K., Maier B., Mauvoisin D., Moriggi E., Gutierrez-Arcelus M., Falconnet E., Borel C., Kunz D. et al., 2017/09/04. eLife, 6 pp. 1-23. Peer-reviewed.
Adequate plasma drug concentrations suggest that amoxicillin can be administered by continuous infusion using elastomeric pumps.
Arensdorff L., Boillat-Blanco N., Decosterd L., Buclin T., de Vallière S., 2017/09/01. The Journal of antimicrobial chemotherapy, 72 (9) pp. 2613-2615. Peer-reviewed.
Ezrin directly interacts with AQP2 and promotes its endocytosis.
Li W., Jin W.W., Tsuji K., Chen Y., Nomura N., Su L., Yui N., Arthur J., Cotecchia S., Paunescu T.G. et al., 2017/09/01. Journal of cell science, 130 (17) pp. 2914-2925. Peer-reviewed.
Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics.
Solis G.P., Bilousov O., Koval A., Lüchtenborg A.M., Lin C., Katanaev V.L., 2017/08/24. Cell, 170 (5) pp. 939-955.e24. Peer-reviewed.
Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.
Mauvoisin D., Atger F., Dayon L., Núñez Galindo A., Wang J., Martin E., Da Silva L., Montoliu I., Collino S., Martin F.P. et al., 2017/08/15. Cell reports, 20 (7) pp. 1729-1743. Peer-reviewed.
Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells.
Rosenbaek L.L., Rizzo F., MacAulay N., Staub O., Fenton R.A., 2017/08/01. American journal of physiology. Renal physiology, 313 (2) pp. F495-F504. Peer-reviewed.
Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.
Al-Qusairi L., Basquin D., Roy A., Rajaram R.D., Maillard M.P., Subramanya A.R., Staub O., 2017/08. Journal of the American Society of Nephrology, 28 (8) pp. 2431-2442. Peer-reviewed.
Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis.
Koppes S.A., Engebretsen K.A., Agner T., Angelova-Fischer I., Berents T., Brandner J., Brans R., Clausen M.L., Hummler E., Jakasa I. et al., 2017/07. Contact dermatitis, 77 (1) pp. 1-16. Peer-reviewed.
Antibiotic stability over six weeks in aqueous solution at body temperature with and without heat treatment that mimics the curing of bone cement.
Samara E., Moriarty T.F., Decosterd L.A., Richards R.G., Gautier E., Wahl P., 2017/05. Bone & joint research, 6 (5) pp. 296-306. Peer-reviewed.
Deletion of Xenotropic and Polytropic Retrovirus Receptor 1 in mouse nephron causes renal Fanconi syndrome and hypophosphatemic rickets [857.9]
Ansermet C., Moor M., Centeno G., Auberson M., Hu D., Barron R., Nikolaeva S., Haenzi B., Katanaeva N., Gautschi I. et al., 2017/04/30., Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting pp. n.p. dans Faseb Journal.
Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating.
Vullo S., Bonifacio G., Roy S., Johner N., Bernèche S., Kellenberger S., 2017/04/04. Proceedings of the National Academy of Sciences of the United States of America, 114 (14) pp. 3768-3773. Peer-reviewed.
Does the type of parenteral lipids matter? A clinical hint in critical illness.
Devaud J.C., Berger M.M., Pannatier A., Sadeghipour F., Voirol P., 2017/04. Clinical nutrition, 36 (2) pp. 491-496. Peer-reviewed.
Pharmacokinetics of Pomalidomide in a Patient Receiving Hemodialysis Using a High-Cutoff Filter.
Dao K., Chtioui H., Lu Y., Peer C.J., Figg W.D., Pruijm M., Buclin T., Kissling S., 2017/04. American journal of kidney diseases, 69 (4) pp. 553-554. Peer-reviewed.
Pharmacometrics-based decision tools facilitate mHealth implementation.
Nekka F., Csajka C., Wilbaux M., Sanduja S., Li J., Pfister M., 2017/04. Expert review of clinical pharmacology, 10 (1) pp. 39-46. Peer-reviewed.
Population Pharmacokinetics and Pharmacogenetics Analysis of Rilpivirine in HIV-1-Infected Individuals.
Aouri M., Barcelo C., Guidi M., Rotger M., Cavassini M., Hizrel C., Buclin T., Decosterd L.A., Csajka C., Swiss HIV Cohort Study, 2017/04. Antimicrobial agents and chemotherapy, 61 (1) p. 10. Peer-reviewed.
Renal Fanconi Syndrome and Hypophosphatemic Rickets in the Absence of Xenotropic and Polytropic Retroviral Receptor in the Nephron.
Ansermet C., Moor M.B., Centeno G., Auberson M., Hu D.Z., Baron R., Nikolaeva S., Haenzi B., Katanaeva N., Gautschi I. et al., 2017/04. Journal of the American Society of Nephrology : JASN, 28 (4) pp. 1073-1078. Peer-reviewed.
Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition.
Shrivastava S., Jeengar M.K., Thummuri D., Koval A., Katanaev V.L., Marepally S., Naidu VGM, 2017/03. BioFactors (Oxford, England), 43 (2) pp. 152-169. Peer-reviewed.
Stem Cell Factor-Based Identification and Functional Properties of In Vitro-Selected Subpopulations of Malignant Mesothelioma Cells
Blum Walter, Pecze László, Felley-Bosco Emanuela, Wu Licun, de Perrot Marc, Schwaller Beat, 2017/03. Stem Cell Reports pp. 73-97. Peer-reviewed.
Atteintes extrarénales de la polykystose rénale: signes cliniques,dépistage et prise en charge [Extra-renal manifestations of the autosomal dominant polycystic kidney disease]
Butscher A., Phan O., Bonny O., 2017/02/22. Revue medicale suisse, 13 (551) pp. 450-456. Peer-reviewed.
Increased bone resorption by osteoclast-specific deletion of the sodium/calcium exchanger isoform 1 (NCX1).
Albano G., Dolder S., Siegrist M., Mercier-Zuber A., Auberson M., Stoudmann C., Hofstetter W., Bonny O., Fuster D.G., 2017/02. Pflugers Archiv, 469 (2) pp. 225-233. Peer-reviewed.
The Hypertension Pandemic: An Evolutionary Perspective.
Rossier B.C., Bochud M., Devuyst O., 2017/02. Physiology (Bethesda, Md.), 32 (2) pp. 112-125. Peer-reviewed.
Selective Deletion of Sodium Salt Taste during Development Leads to Expanded Terminal Fields of Gustatory Nerves in the Adult Mouse Nucleus of the Solitary Tract.
Sun C., Hummler E., Hill D.L., 2017/01/18. The Journal of neuroscience, 37 (3) pp. 660-672. Peer-reviewed.
A Missense Mutation in the Extracellular Domain of αENaC Causes Liddle Syndrome.
Salih M., Gautschi I., van Bemmelen M.X., Di Benedetto M., Brooks A.S., Lugtenberg D., Schild L., Hoorn E.J., 2017. Journal of the American Society of Nephrology, 28 (11) pp. 3291-3299. Peer-reviewed.
AKAP-Lbc mediates protection against doxorubicin-induced cardiomyocyte toxicity.
Caso S., Maric D., Arambasic M., Cotecchia S., Diviani D., 2017. Biochimica et Biophysica Acta. Molecular Cell Research, 1864 (12) pp. 2336-2346. Peer-reviewed.
Alternative moth-eye nanostructures: antireflective properties and composition of dimpled corneal nanocoatings in silk-moth ancestors.
Kryuchkov M., Lehmann J., Schaab J., Cherepanov V., Blagodatski A., Fiebig M., Katanaev V.L., 2017. Journal of Nanobiotechnology, 15 (1) p. 61. Peer-reviewed.
Antireflective nanocoatings for UV-sensation: the case of predatory owlfly insects.
Kryuchkov M., Lehmann J., Schaab J., Fiebig M., Katanaev V.L., 2017. Journal of Nanobiotechnology, 15 (1) p. 52. Peer-reviewed.
AQP2 Abundance is Regulated by the E3-Ligase CHIP Via HSP70.
Centrone M., Ranieri M., Di Mise A., Berlingerio S.P., Russo A., Deen PMT, Staub O., Valenti G., Tamma G., 2017. Cellular Physiology and Biochemistry, 44 (2) pp. 515-531. Peer-reviewed.
Assessment of Cannabis Acute Effects on Driving Skills: Laboratory, Simulator, and On-Road Studies
Bondallaz P., Chtioui H., Favrat B., Fornari E., Giroud C., Maeder P., 2017. pp. 379-390 dans Handbook of Cannabis and Related Pathologies chap. 39, Elsevier BV.
Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks.
Olivon F., Allard P.M., Koval A., Righi D., Genta-Jouve G., Neyts J., Apel C., Pannecouque C., Nothias L.F., Cachet X. et al., 2017. ACS Chemical Biology, 12 (10) pp. 2644-2651. Peer-reviewed.
Coupling between phosphate and calcium homeostasis: a mathematical model.
Granjon D., Bonny O., Edwards A., 2017. American Journal of Physiology. Renal Physiology, 313 (6) pp. F1181-F1199. Peer-reviewed.
Intravenous lacosamide in status epilepticus: Correlation between loading dose, serum levels, and clinical response.
Perrenoud M., André P., Alvarez V., Stähli C., Decosterd L.A., Rossetti A.O., Novy J., 2017. Epilepsy Research, 135 pp. 38-42. Peer-reviewed.
Long Noncoding RNAs in Cancer and Therapeutic Potential.
Renganathan A., Felley-Bosco E., 2017. Advances in Experimental Medicine and Biology, 1008 pp. 199-222. Peer-reviewed.
Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system.
Toffoli B., Gilardi F., Winkler C., Soderberg M., Kowalczuk L., Arsenijevic Y., Bamberg K., Bonny O., Desvergne B., 2017. PLoS One, 12 (2) pp. e0171474. Peer-reviewed.
Nuclear Proteomics Uncovers Diurnal Regulatory Landscapes in Mouse Liver.
Wang J., Mauvoisin D., Martin E., Atger F., Galindo A.N., Dayon L., Sizzano F., Palini A., Kussmann M., Waridel P. et al., 2017. Cell Metabolism, 25 (1) pp. 102-117. Peer-reviewed.
Pharmacokinetics of lenalidomide during high cut-off dialysis in a patient with multiple myeloma and renal failure.
Dao K., Lu Y., Peer C.J., Figg W.D., Stadelmann R., Burnier M., Buclin T., Kissling S., 2017/01. Cancer chemotherapy and pharmacology, 79 (1) pp. 215-218. Peer-reviewed.
Phosphorylation by NLK inhibits YAP-14-3-3-interactions and induces its nuclear localization.
Moon S., Kim W., Kim S., Kim Y., Song Y., Bilousov O., Kim J., Lee T., Cha B., Kim M. et al., 2017/01. EMBO reports, 18 (1) pp. 61-71.
Posttranscriptional Regulation Controls Calretinin Expression in Malignant Pleural Mesothelioma.
Kresoja-Rakic J., Sulemani M., Kirschner M.B., Ronner M., Reid G., Kao S., Schwaller B., Weder W., Stahel R.A., Felley-Bosco E., 2017. Frontiers in Genetics, 8 p. 70. Peer-reviewed.
Proton and non-proton activation of ASIC channels.
Gautschi I., van Bemmelen M.X., Schild L., 2017. PloS one, 12 (4) pp. e0175293. Peer-reviewed.
Regulation of Mammalian Physiology by Interconnected Circadian and Feeding Rhythms.
Atger F., Mauvoisin D., Weger B., Gobet C., Gachon F., 2017. Frontiers in endocrinology, 8 p. 42. Peer-reviewed.
The levels of vancomycin in the blood and the wound after the local treatment of bone and soft-tissue infection with antibiotic-loaded calcium sulphate as carrier material.
Wahl P., Guidi M., Benninger E., Rönn K., Gautier E., Buclin T., Magnin J.L., Livio F., 2017. The Bone & Joint Journal, 99-B (11) pp. 1537-1544. Peer-reviewed.
The role of A-kinase anchoring proteins in cancer development.
Reggi E., Diviani D., 2017. Cellular Signalling, 40 pp. 143-155. Peer-reviewed.
Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis.
Keppner A., Malsure S., Nobile A., Auberson M., Bonny O., Hummler E., 2016/12. Inflammatory bowel diseases, 22 (12) pp. 2824-2839. Peer-reviewed.
Population Genetic-Based Pharmacokinetic Modeling of Methadone and its Relationship with the QTc Interval in Opioid-Dependent Patients.
Csajka C., Crettol S., Guidi M., Eap C.B., 2016/12. Clinical pharmacokinetics, 55 (12) pp. 1521-1533. Peer-reviewed.
A model of calcium homeostasis in the rat.
Granjon D., Bonny O., Edwards A., 2016/11/01. American journal of physiology. Renal physiology, 311 (5) pp. F1047-F1062. Peer-reviewed.
Low Merlin expression and high Survivin labeling index are indicators for poor prognosis in patients with malignant pleural mesothelioma
Meerang Mayura, Bérard Karima, Friess Martina, Bitanihirwe Byron K.Y., Soltermann Alex, Vrugt Bart, Felley-Bosco Emanuela, Bueno Raphael, Richards William G., Seifert Burkhardt et al., 2016/10. Molecular Oncology, 10 (8) pp. 1255-1265. Peer-reviewed.
Nephron-Specific Deletion of Circadian Clock Gene Bmal1 Alters the Plasma and Renal Metabolome and Impairs Drug Disposition.
Nikolaeva S., Ansermet C., Centeno G., Pradervand S., Bize V., Mordasini D., Henry H., Koesters R., Maillard M., Bonny O. et al., 2016/10. Journal of the American Society of Nephrology : JASN, 27 (10) pp. 2997-3004. Peer-reviewed.
The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.
Boscardin E., Alijevic O., Hummler E., Frateschi S., Kellenberger S., 2016/09. British Journal of Pharmacology, 173 (18) pp. 2671-2701. Peer-reviewed.
Comparison of Population Pharmacokinetics Based on Steady-State Assumption Versus Electronically Monitored Adherence to Lopinavir, Atazanavir, Efavirenz, and Etravirine: A Retrospective Study.
Fuchs A., Rotzinger A., Cavassini M., Bugnon O., Buclin T., Schneider M.P., Csajka C., 2016/08. Therapeutic drug monitoring, 38 (4) pp. 506-515. Peer-reviewed.
Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.
Al-Qusairi L., Basquin D., Roy A., Stifanelli M., Rajaram R.D., Debonneville A., Nita I., Maillard M., Loffing J., Subramanya A.R. et al., 2016/08/01. American journal of physiology. Renal physiology, 311 (2) pp. F330-42. Peer-reviewed.
Severe Salt-Losing Syndrome and Hyperkalemia Induced by Adult Nephron-Specific Knockout of the Epithelial Sodium Channel α-Subunit.
Perrier R., Boscardin E., Malsure S., Sergi C., Maillard M.P., Loffing J., Loffing-Cueni D., Sørensen M.V., Koesters R., Rossier B.C. et al., 2016/08. Journal of the American Society of Nephrology, 27 (8) pp. 2309-2318. Peer-reviewed.
A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers.
Ahmed K., Shaw H.V., Koval A., Katanaev V.L., 2016/07/14. Cancers, 8 (7) pp. 1-27.
Emerging roles of A-kinase anchoring proteins in cardiovascular pathophysiology
Diviani Dario, Reggi Erica, Arambasic Miroslav, Caso Stefania, Maric Darko, 2016/07. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (7) pp. 1926-1936. Peer-reviewed.
Pregnancy outcome following maternal exposure to pregabalin may call for concern.
Winterfeld U., Merlob P., Baud D., Rousson V., Panchaud A., Rothuizen L.E., Bernard N., Vial T., Yates L.M., Pistelli A. et al., 2016/06/14. Neurology, 86 (24) pp. 2251-2257. Peer-reviewed.
Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype.
Canonica J., Sergi C., Maillard M., Klusonova P., Odermatt A., Koesters R., Loffing-Cueni D., Loffing J., Rossier B., Frateschi S. et al., 2016/05. Pflugers Archiv : European journal of physiology, 468 (5) pp. 895-908. Peer-reviewed.
Perturbed rhythmic activation of signaling pathways in mice deficient for Sterol Carrier Protein 2-dependent diurnal lipid transport and metabolism.
Jouffe C., Gobet C., Martin E., Métairon S., Morin-Rivron D., Masoodi M., Gachon F., 2016/04/21. Scientific reports, 6 p. 24631. Peer-reviewed.
Outbreak in meldonium positive laboratory tests: are we missing something?
Panchaud A., Csajka C., 2016/04. British journal of sports medicine, 50 (22) pp. 1422-1423. Peer-reviewed.
Antagonizing the Hedgehog Pathway with Vismodegib Impairs Malignant Pleural Mesothelioma Growth In Vivo by Affecting Stroma.
Meerang M., Bérard K., Felley-Bosco E., Lauk O., Vrugt B., Boss A., Kenkel D., Broggini-Tenzer A., Stahel R.A., Arni S. et al., 2016. Molecular Cancer Therapeutics pp. 1095-105. Peer-reviewed.
Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways.
Crippa S., Nemir M., Ounzain S., Ibberson M., Berthonneche C., Sarre A., Boisset G., Maison D., Harshman K., Xenarios I. et al., 2016. Cardiovascular Research, 110 (1) pp. 73-84. Peer-reviewed.
Emerging Role of Zika Virus in Adverse Fetal and Neonatal Outcomes.
Panchaud A., Stojanov M., Ammerdorffer A., Vouga M., Baud D., 2016. Clinical Microbiology Reviews, 29 (3) pp. 659-694. Peer-reviewed.
Extracellular K(+) rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl(-) -dependent and independent mechanisms.
Penton D., Czogalla J., Wengi A., Himmerkus N., Loffing-Cueni D., Carrel M., Rajaram R.D., Staub O., Bleich M., Schweda F. et al., 2016. The Journal of Physiology, 594 (21) pp. 6319-6331. Peer-reviewed.
Inhibition of Wnt signalling and breast tumour growth by the multi-purpose drug suramin through suppression of heterotrimeric G proteins and Wnt endocytosis.
Koval A., Ahmed K., Katanaev V.L., 2016. Biochemical Journal, 473 (4) pp. 371-381. Peer-reviewed.
Les maladies rénales chroniques ne sont pas toutes silencieuses [Chronic kidney diseases do not always pass unnoticed].
Alves C., Pruijma M., Rotman S., Bonny O., 2016. Revue Médicale Suisse, 12 (507) pp. 382-386. Peer-reviewed.
Osmoregulation during Long-Term Fasting in Lungfish and Elephant Seal: Old and New Lessons for the Nephrologist.
Rossier B.C., 2016. Nephron, 134 (1) pp. 5-9. Peer-reviewed.
Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates.
Wilbaux M., Fuchs A., Samardzic J., Rodieux F., Csajka C., Allegaert K., van den Anker J.N., Pfister M., 2016. Journal of Clinical Pharmacology, 56 (8) pp. 909-935. Peer-reviewed.
Reducing αENaC expression in the kidney connecting tubule induces pseudohypoaldosteronism type 1 symptoms during K+ loading.
Poulsen S.B., Praetorius J., Damkier H.H., Miller L., Nelson R.D., Hummler E., Christensen B.M., 2016. American Journal of Physiology. Renal Physiology, 310 (4) pp. F300-F310. Peer-reviewed.
Safety of drugs during pregnancy and breastfeeding in cystic fibrosis patients.
Panchaud A., Di Paolo E.R., Koutsokera A., Winterfeld U., Weisskopf E., Baud D., Sauty A., Csajka C., 2016. Respiration; international review of thoracic diseases, 91 (4) pp. 333-348. Peer-reviewed.
Small-Molecule Protein-Protein Interaction Inhibitor of Oncogenic Rho Signaling.
Diviani D., Raimondi F., Del Vescovo C.D., Dreyer E., Reggi E., Osman H., Ruggieri L., Gonano C., Cavin S., Box C.L. et al., 2016. Cell Chemical Biology, 23 (9) pp. 1135-1146. Peer-reviewed.
The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.
Kühn N., Bergmann S., Kösterke N., Lambertz R.L., Keppner A., van den Brand J.M., Pöhlmann S., Weiß S., Hummler E., Hatesuer B. et al., 2016. Journal of Virology, 90 (9) pp. 4298-4307. Peer-reviewed.
Therapeutic drug monitoring for sofosbuvir and daclatasvir in transplant recipients with chronic hepatitis C and advanced renal disease.
Vionnet J., Saouli A.C., Pascual M., Stucker F., Decosterd L.A., Moradpour D., Chtioui H., 2016. Journal of Hepatology, 65 (5) pp. 1063-1065. Peer-reviewed.
USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.
Pouly D., Chenaux S., Martin V., Babis M., Koch R., Nagoshi E., Katanaev V.L., Gachon F., Staub O., 2016. Plos One, 11 (1) pp. e0145155. Peer-reviewed.
Utility of an Algorithm to Increase the Accuracy of Medication History in an Obstetrical Setting.
Corbel A., Baud D., Chaouch A., Beney J., Csajka C., Panchaud A., 2016. Plos One, 11 (3) pp. e0151205. Peer-reviewed.
Ways of calcium reabsorption in the kidney.
Moor M.B., Bonny O., 2016. American Journal of Physiology. Renal Physiology, 310 (11) pp. F1337-F1350. Peer-reviewed.
Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis.
Valenta T., Degirmenci B., Moor A.E., Herr P., Zimmerli D., Moor M.B., Hausmann G., Cantù C., Aguet M., Basler K., 2016. Cell reports, 15 (5) pp. 911-918. Peer-reviewed.
Furosemide stimulation of parathormone in humans: role of the calcium-sensing receptor and the renin-angiotensin system.
Muller M.E., Forni Ogna V., Maillard M., Stoudmann C., Zweiacker C., Anex C., Wuerzner G., Burnier M., Bonny O., 2015/12. Pflugers Archiv, 467 (12) pp. 2413-2421. Peer-reviewed.
5C.09: Heritability of renal function parameters and electrolyte levels in the Swiss population
Moulin F., Ponte B., Pruijm M., Ackermann D., Guessous I., Ehret G., Bonny O., Pechere-Bertschi A., Staessen J.A., Paccaud F. et al., 2015/06., ESH 2015: 25th European meeting on hypertension and cardiovascular protection, 12-15 June 2015, Milan (Italy) pp. e70 dans J Hypertension. Peer-reviewed.
Pregnancy outcome following maternal exposure to mirtazapine: a multicenter, prospective study.
Winterfeld U., Klinger G., Panchaud A., Stephens S., Arnon J., Malm H., Te Winkel B., Clementi M., Pistelli A., Maňáková E. et al., 2015/06. Journal of Clinical Psychopharmacology, 35 (3) pp. 250-259. Peer-reviewed.
Sodium-dependent phosphate transporters in osteoclast differentiation and function.
Albano G., Moor M., Dolder S., Siegrist M., Wagner C.A., Biber J., Hernando N., Hofstetter W., Bonny O., Fuster D.G., 2015/04. Plos One, 10 (4) pp. e0125104. Peer-reviewed.
L'oxalate: un déchet organique peu soluble, avec conséquences [Oxalate: a poorly soluble organic waste with consequences].
Lu Y., Bonny O., 2015/03. Praxis, 104 (7) pp. 353-359.
Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.
Piazzon N., Bernet F., Guihard L., Leonhard W.N., Urfer S., Firsov D., Chehade H., Vogt B., Piergiovanni S., Peters D.J. et al., 2015/03. Journal of Translational Medicine, 13 p. 103. Peer-reviewed.
Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischemia and acidosis in hippocampal CA1 neurons
Quintana P., Soto D., Poirot O., Zonouzi M., Kellenberger S., Muller D., Chrast R., Cull-Candy S.G., 2015. Journal of Physiology, 593 (19) pp. 4373-4386. Peer-reviewed.
Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.
Roy A., Al-Qusairi L., Donnelly B.F., Ronzaud C., Marciszyn A.L., Gong F., Chang Y.P., Butterworth M.B., Pastor-Soler N.M., Hallows K.R. et al., 2015. Journal of Clinical Investigation, 125 (9) pp. 3433-3448. Peer-reviewed.
Architectural and Functional Similarities between Trimeric ATP-Gated P2X Receptors and Acid-Sensing Ion Channels
Kellenberger S., Grutter T., 2015. Journal of Molecular Biology, 427 (1) pp. 54-66. Peer-reviewed.
Association of urinary calcium excretion with serum calcium and vitamin D levels.
Rathod A., Bonny O., Guessous I., Suter P.M., Conen D., Erne P., Binet I., Gabutti L., Gallino A., Muggli F. et al., 2015. Clinical Journal of the American Society of Nephrology, 10 (3) pp. 452-462. Peer-reviewed.
BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.
Moor A.E., Anderle P., Cantù C., Rodriguez P., Wiedemann N., Baruthio F., Deka J., André S., Valenta T., Moor M.B. et al., 2015. Ebiomedicine, 2 (12) pp. 1932-1943. Peer-reviewed.
Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver.
Atger F., Gobet C., Marquis J., Martin E., Wang J., Weger B., Lefebvre G., Descombes P., Naef F., Gachon F., 2015. Proceedings of the National Academy of Sciences of the United States of America, 112 (47) pp. E6579-E6588. Peer-reviewed.
Diverse set of Turing nanopatterns coat corneae across insect lineages.
Blagodatski A., Sergeev A., Kryuchkov M., Lopatina Y., Katanaev V.L., 2015. Proceedings of the National Academy of Sciences of the United States of America, 112 (34) pp. 10750-10755. Peer-reviewed.
Effective Treatment of Invasive Aspergillus fumigatus Infection Using Combinations of Topical and Systemic Antifungals in a Severely Burned Patient.
Fournier A., Pantet O., Guerid S., Eggimann P., Pagani J.L., Revelly J.P., Hauser P.M., Marchetti O., Fontanella S., Letovanec I. et al., 2015. Journal of Burn Care and Research, 36 (2) pp. e85-e89. Peer-reviewed.
ENaC activity in collecting ducts modulates NCC in cirrhotic mice.
Mordasini D., Loffing-Cueni D., Loffing J., Beatrice R., Maillard M.P., Hummler E., Burnier M., Escher G., Vogt B., 2015. Pflügers Archiv : European Journal of Physiology, 467 (12) pp. 2529-2539. Peer-reviewed.
Epithelial Sodium Channel-Mediated Sodium Transport Is Not Dependent on the Membrane-Bound Serine Protease CAP2/Tmprss4.
Keppner A., Andreasen D., Mérillat A.M., Bapst J., Ansermet C., Wang Q., Maillard M., Malsure S., Nobile A., Hummler E., 2015. Plos One, 10 (8) pp. e0135224. Peer-reviewed.
Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited.
Rossier B.C., Baker M.E., Studer R.A., 2015. Physiological Reviews, 95 (1) pp. 297-340. Peer-reviewed.
Extracellular Subunit Interactions Control Transitions between Functional States of Acid-sensing Ion Channel 1a.
Gwiazda K., Bonifacio G., Vullo S., Kellenberger S., 2015. Journal of Biological Chemistry, 290 (29) pp. 17956-17966. Peer-reviewed.
Identification of pyridine analogs as new predator-derived kairomones.
Brechbühl J., Moine F., Tosato M.N., Sporkert F., Broillet M.C., 2015. Frontiers In Neuroscience, 9 p. 253. Peer-reviewed.
Improved investigations in drug safety by more in-depth individual pharmacokinetics using high-resolution mass spectrometry.
Rochat B., Dahmane E., Zaman K., Csajka C., 2015. Therapeutic Drug Monitoring, 37 (2) pp. 141-146.
International union of basic and clinical pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel.
Kellenberger S., Schild L., 2015. Pharmacological Reviews, 67 (1) pp. 1-35. Peer-reviewed.
Local Salmonella immunostimulation recruits vaccine-specific CD8 T cells and increases regression of bladder tumor.
Domingos-Pereira S., Hojeij R., Reggi E., Derré L., Chevalier M.F., Romero P., Jichlinski P., Nardelli-Haefliger D., 2015. Oncoimmunology, 4 (7) pp. e1016697. Peer-reviewed.
Mode of interaction of the Gαo subunit of heterotrimeric G proteins with the GoLoco1 motif of Drosophila Pins is determined by guanine nucleotides.
Lüchtenborg A.M., Purvanov V., Melnik B.S., Becker S., Katanaev V.L., 2015. Bioscience Reports, 35 (6) pp. e00271. Peer-reviewed.
NEDD4-2 and salt-sensitive hypertension.
Rizzo F., Staub O., 2015. Current Opinion in Nephrology and Hypertension, 24 (2) pp. 111-116. Peer-reviewed.
No development of hypertension in the hyperuricemic liver-Glut9 knockout mouse.
Preitner F., Pimentel A., Metref S., Berthonneche C., Sarre A., Moret C., Rotman S., Centeno G., Firsov D., Thorens B., 2015. Kidney International, 87 (5) pp. 940-947.
Patients âgés traités par chimiothérapie. Apports d'une approche interdisciplinaire
Foley R.-A., Ansermet C., Anchisi A., Anchisi S., 2015. Bulletin des Médecins Suisses, 96 (4) pp. 94-97. Peer-reviewed.
Pediatric reference intervals for plasma free and total metanephrines established with a parametric approach: Relevance to the diagnosis of neuroblastoma.
Franscini L.C., Vazquez-Montes M., Buclin T., Perera R., Dunand M., Grouzmann E., Beck-Popovic M., 2015. Pediatric Blood and Cancer, 62 (4) pp. 587-593. Peer-reviewed.
Physicochemical aspects and efficiency of albuterol nebulization: comparison of three aerosol types in an in vitro pediatric model.
Sidler-Moix A.L., Di Paolo E.R., Dolci U., Berger-Gryllaki M., Cotting J., Pannatier A., 2015. Respiratory Care, 60 (1) pp. 38-46.
PPARγ Agonist-Induced Fluid Retention Depends on αENaC Expression in Connecting Tubules.
Fu Y., Gerasimova M., Batz F., Kuczkowski A., Alam Y., Sanders P.W., Ronzaud C., Hummler E., Vallon V., 2015. Nephron. Physiology, 129 (1) pp. 68-74. Peer-reviewed.
Pregnancy outcome after TNF-α inhibitor therapy during the first trimester: a prospective multicentre cohort study.
Weber-Schoendorfer C., Oppermann M., Wacker E., Bernard N., network of French pharmacovigilance centres, Beghin D., Beghin D., Cuppers-Maarschalkerweerd B., Richardson J.L., Rothuizen L.E. et al., 2015. British Journal of Clinical Pharmacology, 80 (4) pp. 727-739. Peer-reviewed.
Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a.
Hülsbusch N., Solis G.P., Katanaev V.L., Stuermer C.A., 2015. European Journal of Cell Biology, 94 (11) pp. 531-545. Peer-reviewed.
Regulation of blood pressure and renal function by NCC and ENaC: lessons from genetically engineered mice.
Verouti S.N., Boscardin E., Hummler E., Frateschi S., 2015. Current Opinion in Pharmacology, 21C pp. 60-72. Peer-reviewed.
Risk Behavior and Reciprocity of Organ Donation Attitudes in Young Men.
Vetterli D.C., Lava S.A., Essig S., Milosevic G., Cajöri G., Uehlinger D.E., Moor M.B., 2015. Transplantation Proceedings, 47 (6) pp. 1560-1566. Peer-reviewed.
Tgfbi/Bigh3 silencing activates ERK in mouse retina.
Allaman-Pillet N., Oberson A., Bustamante M., Tasinato A., Hummler E., Schorderet D.F., 2015. Experimental Eye Research, 140 pp. 159-170. Peer-reviewed.
The alpha1-adrenergic receptors in cardiac hypertrophy: Signaling mechanisms and functional implications.
Cotecchia S., Del Vescovo C.D., Colella M., Caso S., Diviani D., 2015. Cellular Signalling, 27 (10) pp. 1984-1993. Peer-reviewed.
The Human Acid-Sensing Ion Channel ASIC1a: Evidence for a Homotetrameric Assembly State at the Cell Surface.
van Bemmelen M.X., Huser D., Gautschi I., Schild L., 2015. Plos One, 10 (8) pp. e0135191. Peer-reviewed.
The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.
Brunati M., Perucca S., Han L., Cattaneo A., Consolato F., Andolfo A., Schaeffer C., Olinger E., Peng J., Santambrogio S. et al., 2015. Elife, 4 pp. e08887. Peer-reviewed.
Coordinated regulation of TRPV5-mediated Ca²⁺ transport in primary distal convolution cultures.
van der Hagen E.A., Lavrijsen M., van Zeeland F., Praetorius J., Bonny O., Bindels R.J., Hoenderop J.G., 2014/11. Pflügers Archiv : European Journal of Physiology, 466 (11) pp. 2077-2087. Peer-reviewed.
The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin-1 (PN-1) inhibition.
Crisante G., Battista L., Iwaszkiewicz J., Nesca V., Mérillat A.M., Sergi C., Zoete V., Frateschi S., Hummler E., 2014/11. Faseb Journal, 28 pp. 1-14. Peer-reviewed.
La lithiase rénale: un marqueur du risque cardiovasculaire [Kidney stone as a cardiovascular risk marker].
Ernandez T., Bonny O., 2014/09. Revue Médicale Suisse, 10 (441) pp. 1656-1660.
Circadian glomerular function: from physiology to molecular and therapeutical aspects.
Wuerzner G., Firsov D., Bonny O., 2014/08. Nephrology, Dialysis, Transplantation, 29 (8) pp. 1475-1480. Peer-reviewed.
Calcium entry via TRPV1 but not ASICs induces neuropeptide release from sensory neurons
Boillat A., Alijevic O., Kellenberger S., 2014/04. Molecular and Cellular Neuroscience, 61 pp. 13-22. Peer-reviewed.
A-kinase anchoring protein-Lbc promotes pro-fibrotic signaling in cardiac fibroblasts
Cavin Sabrina, Maric Darko, Diviani Dario, 2014/02. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1843 (2) pp. 335-345. Peer-reviewed.
Generation of TALEN-mediated GRdim knock-in rats by homologous recombination.
Ponce de León V., Mérillat A.M., Tesson L., Anegón I., Hummler E., 2014/02. Plos One, 9 (2) pp. e88146. Peer-reviewed.
A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.
Glaudemans B., Terryn S., Gölz N., Brunati M., Cattaneo A., Bachi A., Al-Qusairi L., Ziegler U., Staub O., Rampoldi L. et al., 2014. Pflügers Archiv : European Journal of Physiology, 466 (2) pp. 343-356. Peer-reviewed.
Anti-leprosy drug clofazimine inhibits growth of triple-negative breast cancer cells via inhibition of canonical Wnt signaling.
Koval A.V., Vlasov P., Shichkova P., Khunderyakova S., Markov Y., Panchenko J., Volodina A., Kondrashov F.A., Katanaev V.L., 2014. Biochemical Pharmacology, 87 (4) pp. 571-578. Peer-reviewed.
Antiepileptika bei Frauen im gebärfähigen Alter und in der Schwangerschaft : Vergleich der Fachinformationen in Deutschland und der Schweiz mit dem aktuellen Wissensstand [Antiepileptics in women of childbearing age and during pregnancy : Comparison of specialized information with the current state of knowledge in Germany and Switzerland].
Winterfeld U., Gotta V., Rothuizen L.E., Panchaud A., Rossetti A.O., Buclin T., 2014. Der Nervenarzt, 85 (6) pp. 738-746. Peer-reviewed.
Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver.
Mauvoisin D., Wang J., Jouffe C., Martin E., Atger F., Waridel P., Quadroni M., Gachon F., Naef F., 2014. Proceedings of the National Academy of Sciences of the United States of America, 111 (1) pp. 167-172.
Colon-specific deletion of epithelial sodium channel causes sodium loss and aldosterone resistance.
Malsure S., Wang Q., Charles R.P., Sergi C., Perrier R., Christensen B.M., Maillard M., Rossier B.C., Hummler E., 2014. Journal of the American Society of Nephrology, 25 (7) pp. 1453-1464. Peer-reviewed.
Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A.
García Segarra N., Gautschi I., Mittaz-Crettol L., Kallay Zetchi C., Al-Qusairi L., Van Bemmelen M.X., Maeder P., Bonafé L., Schild L., Roulet-Perez E., 2014. Journal of the Neurological Sciences, 342 (1-2) pp. 69-78. Peer-reviewed.
Daptomycin-associated eosinophilic pneumonia in two patients with prosthetic joint infection.
Yusuf E., Perrottet N., Orasch C., Borens O., Trampuz A., 2014. Surgical Infections, 15 (6) pp. 834-837. Peer-reviewed.
Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles.
Schütz C.A., Staedler D., Crosbie-Staunton K., Movia D., Chapuis Bernasconi C., Kenzaoui B.H., Prina-Mello A., Juillerat-Jeanneret L., 2014. International Journal of Nanomedicine, 9 pp. 3481-3498. Peer-reviewed.
Disuse deterioration of human skeletal muscle challenged by resistive exercise superimposed with vibration: evidence from structural and proteomic analysis.
Salanova M., Gelfi C., Moriggi M., Vasso M., Viganò A., Minafra L., Bonifacio G., Schiffl G., Gutsmann M., Felsenberg D. et al., 2014. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology, 28 (11) pp. 4748-4763. Peer-reviewed.
Double suppression of the Gα protein activity by RGS proteins.
Lin C., Koval A., Tishchenko S., Gabdulkhakov A., Tin U., Solis G.P., Katanaev V.L., 2014. Molecular Cell, 53 (4) pp. 663-671. Peer-reviewed.
Epithelial sodium channel (ENaC) and the control of blood pressure.
Rossier B.C., 2014. Current Opinion In Pharmacology, 15 (3) pp. 33-46. Peer-reviewed.
Expression, purification, and structural insights for the human uric acid transporter, GLUT9, using the Xenopus laevis oocytes system.
Clémençon B., Lüscher B.P., Fine M., Baumann M.U., Surbek D.V., Bonny O., Hediger M.A., 2014. Plos One, 9 (10) pp. e108852. Peer-reviewed.
Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.
Faller N., Gautschi I., Schild L., 2014. Plos One, 9 (4) pp. e94267. Peer-reviewed.
Genetics of calcium homeostasis in humans: continuum between monogenic diseases and continuous phenotypes
Bonny O., Bochud M., 2014. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 29 (suppl 4) pp. iv55-iv62. Peer-reviewed.
Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeleton.
Lüchtenborg A.M., Solis G.P., Egger-Adam D., Koval A., Lin C., Blanchard M.G., Kellenberger S., Katanaev V.L., 2014. Development, 141 (17) pp. 3399-3409. Peer-reviewed.
High-throughput hydrophilic interaction chromatography coupled to tandem mass spectrometry for the optimized quantification of the anti-Gram-negatives antibiotic colistin A/B and its pro-drug colistimethate.
Mercier T., Tissot F., Gardiol C., Corti N., Wehrli S., Guidi M., Csajka C., Buclin T., Couet W., Marchetti O. et al., 2014. Journal of Chromatography. A, 1369 pp. 52-63. Peer-reviewed.
Hypoxia-induced inhibition of epithelial Na(+) channels in the lung. Role of Nedd4-2 and the ubiquitin-proteasome pathway.
Gille T., Randrianarison-Pellan N., Goolaerts A., Dard N., Uzunhan Y., Ferrary E., Hummler E., Clerici C., Planès C., 2014. American Journal of Respiratory Cell and Molecular Biology, 50 (3) pp. 526-537. Peer-reviewed.
Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases.
Bilousov O., Koval A., Keshelava A., Katanaev V.L., 2014. Plos One, 9 (6) pp. e101133. Peer-reviewed.
Lack of evidence of the interaction of the Aß peptide with the Wnt signaling cascade in Drosophila models of Alzheimer's disease.
Lüchtenborg A.M., Katanaev V.L., 2014. Molecular Brain, 7 (1) p. 81. Peer-reviewed.
Local Renal Circadian Clocks Control Fluid-Electrolyte Homeostasis and BP.
Tokonami N., Mordasini D., Pradervand S., Centeno G., Jouffe C., Maillard M., Bonny O., Gachon F., Gomez R.A., Sequeira-Lopez M.L. et al., 2014. Journal of the American Society of Nephrology, 25 (7) pp. 1430-1439.
Loss of Memo, a novel FGFR regulator, results in reduced lifespan.
Haenzi B., Bonny O., Masson R., Lienhard S., Dey J.H., Kuro-o M., Hynes N.E., 2014/01. Faseb Journal, 28 (1) pp. 327-336. Peer-reviewed.
Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model.
Perentes J.Y., Wang Y., Wang X., Abdelnour E., Gonzalez M., Decosterd L., Wagnieres G., van den Bergh H., Peters S., Ris H.B. et al., 2014. Translational Oncology, 7 (3) pp. 393-399. Peer-reviewed.
Measuring surface potential changes on leaves.
Mousavi S.A., Nguyen C.T., Farmer E.E., Kellenberger S., 2014. Nature Protocols, 9 (8) pp. 1997-2004. Peer-reviewed.
Morphological and physiological species-dependent characteristics of the rodent Grueneberg ganglion.
Brechbühl J., Klaey M., Moine F., Bovay E., Hurni N., Nenniger-Tosato M., Broillet M.C., 2014. Frontiers in Neuroanatomy, 8 p. 87. Peer-reviewed.
Médicaments et grossesse : modifications pharmacocinétiques et place du suivi thérapeutique pharmacologique [Pharmacokinetic Alterations in Pregnancy and Use of Therapeutic Drug Monitoring].
Panchaud A., Weisskopf E., Winterfeld U., Baud D., Guidi M., Eap C.B., Csajka C., Widmer N., 2014. Therapie, 69 (3) pp. 223-234. Peer-reviewed.
Place de l'enseignement à distance dans l'éducation et la formation du chercheur [Role of distance learning in the education and the training of the investigator].
Rossier B.C., Kraehenbuhl J.P., Rossier M., 2014. Médecine Sciences : M/s, 30 (6-7) pp. 603-604. Peer-reviewed.
Population pharmacokinetic approach to evaluate the effect of CYP2D6, CYP3A, ABCB1, POR and NR1I2 genotypes on donepezil clearance.
Noetzli M., Guidi M., Ebbing K., Eyer S., Wilhelm L., Michon A., Thomazic V., Stancu I., Alnawaqil A.M., Bula C. et al., 2014. British Journal of Clinical Pharmacology, 78 (1) pp. 135-144. Peer-reviewed.
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