Department of Immunobiology

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2186 publications

En préparation
Uniting Machine Intelligence, Brain and Behavioural Sciences to Assist Criminal Justice.
Chén Oliver Y.
[URN][serval:BIB_D2B7729FCF9B]
On Statistical Analysis of Brain Variability.
Chén Oliver Y, Phan Huy, Nagels Guy, de Vos Maarten.
[URN][serval:BIB_91CE28099425]
In press
 
PD1 inhibits PKCθ-dependent phosphorylation of cytoskeleton-related proteins and immune synapse formation.
Chmiest D., Podavini S., Ioannidou K., Vallois D., Décaillet C., Gonzalez M., Quadroni M., Blackney K., Schairer R., de Leval L.L. et al. Blood advances. Peer-reviewed.
[DOI][Pmid][serval:BIB_E176D0DCD829]
 
Author Correction: The DExD/H-box helicase Dicer-2 mediates the induction of antiviral activity in drosophila.
Deddouche S., Matt N., Budd A., Mueller S., Kemp C., Galiana-Arnoux D., Dostert C., Antoniewski C., Hoffmann J.A., Imler J.L. Nature immunology. Peer-reviewed.
[DOI][Pmid][serval:BIB_6315CF0DA1FC]
 
Extracellular vesicle miRNAs drive aberrant macrophage responses in NSAID-exacerbated respiratory disease.
Hartung F., Haimerl P., Schindela S., Mussack V., Kirchner B., Henkel FDR, Bernhardt U., Zissler U.M., Santarella-Mellwig R., Pfaffl M. et al. Allergy. Peer-reviewed.
[DOI][Pmid][serval:BIB_2572ABA6A7A8]
 
Climbing into their Skin to Understand Contextual Protein-Protein Associations and Localizations: Functional Investigations in Transgenic Live Model Organisms.
Long MJC, Aye Y. Chembiochem. Peer-reviewed.
[DOI][Pmid][serval:BIB_0739F71EFEB9]
 
Formaldehyde regulates one-carbon metabolism and epigenetics.
Long MJC, Aye Y. Trends in genetics. Peer-reviewed.
[DOI][Pmid][serval:BIB_7AF9ECABA57F]
2024
 
A rhodamine-6G based chromo and fluorogenic sensor for the selective turn-ON detection of Fe3+ in aqueous medium with potential applications as INHIBIT logic gate, memory device and live cell imaging
Das Dipankar, Alam Rabiul, Sasmal Mihir, Katarkar Atul, Dutta Ananya, Ali Mahammad, 2024/04. Inorganica Chimica Acta, 563 p. 121902.
[DOI][WoS][serval:BIB_037FA51F7E8D]
 
NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis.
Ramos S., Hartenian E., Santos J.C., Walch P., Broz P., 2024/04. The EMBO journal, 43 (7) pp. 1164-1186. Peer-reviewed.
[DOI][Pmid][serval:BIB_E885446D4A15]
 
The β-Carboline Harmine Has a Protective Immunomodulatory Role in Nonhealing Cutaneous Leishmaniasis.
Peyvandi S., Lan Q., Chabloz A., Prével F., La Torre Y.H., Ives A., Tacchini-Cottier F., 2024/04. The Journal of investigative dermatology, 144 (4) pp. 862-873.e4. Peer-reviewed.
[DOI][Pmid][serval:BIB_946D53B570D6]
Selective induction of programmed cell death using synthetic biology tools.
Shkarina K., Broz P., 2024/03/15. Seminars in cell & developmental biology, 156 pp. 74-92. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_2EE059EAF4AC]
HSP90β controls NLRP3 autoactivation.
Spel L., Hou C., Theodoropoulou K., Zaffalon L., Wang Z., Bertoni A., Volpi S., Hofer M., Gattorno M., Martinon F., 2024/03. Science advances, 10 (9) pp. eadj6289. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D489F461335C]
Nucleosides are overlooked fuels in central carbon metabolism.
Strefeler A., Blanco-Fernandez J., Jourdain A.A., 2024/02/29. Trends in endocrinology and metabolism. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8D78753B22EF]
 
ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation.
Mazzeo L., Ghosh S., Di Cicco E., Isma J., Tavernari D., Samarkina A., Ostano P., Youssef M.K., Simon C., Dotto G.P., 2024/02/03. Nature communications, 15 (1) p. 1038. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2999AA526D89]
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism.
Meisel J.D., Miranda M., Skinner O.S., Wiesenthal P.P., Wellner S.M., Jourdain A.A., Ruvkun G., Mootha V.K., 2024/02/01. Cell, 187 (3) pp. 659-675.e18. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F54B92E382BB]
PD-1 checkpoint inhibition enhances the antilymphoma activity of CD19-CAR-iNKT cells that retain their ability to prevent alloreactivity.
Moraes Ribeiro E., Secker K.A., Nitulescu A.M., Schairer R., Keppeler H., Wesle A., Schmid H., Schmitt A., Neuber B., Chmiest D. et al., 2024/01/31. Journal for immunotherapy of cancer, 12 (1) pp. e007829. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B2017EE05F21]
 
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells.
Staniek J., Kalina T., Andrieux G., Boerries M., Janowska I., Fuentes M., Díez P., Bakardjieva M., Stancikova J., Raabe J. et al., 2024/01/12. Science immunology, 9 (91) pp. eadj5948. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1B6384117153]
 
A self-assembled nanoprobe based on Schiff base for the rapid and selective detection of serum albumin with cell imaging applications
Moni Dolan, Sasmal Mihir, Islam Abu Saleh Musha, Dutta Ananya, Maiti Debjani, Khatun Rousunara, Katarkar Atul, Ali Mahammad, 2024. New Journal of Chemistry, 48 (1) pp. 351-358.
[DOI][WoS][serval:BIB_76541BBB924A]
 
An unappreciated cell survival-independent role for BAFF initiating chronic lymphocytic leukemia.
Ullah M.A., Garcillán B., Whitlock E., Figgett W.A., Infantino S., Eslami M., Yang S., Rahman M.A., Sheng Y.H., Weber N. et al., 2024. Frontiers in immunology, 15 p. 1345515. Peer-reviewed.
[DOI][Pmid][serval:BIB_BFA034F2D5DF]
 
Career pathways, part 13.
Jourdain A.A., Wang F., 2024/01. Nature metabolism, 6 (1) pp. 2-5. Peer-reviewed.
[DOI][Pmid][serval:BIB_87D5EE21DA57]
 
Recovering from the stress of the COVID-19 pandemic
Lewis Samantha C., Jourdain Alexis A., Schulman Brenda A., Vousden Karen H., Fabius Jacqueline M., Liu Haipeng, 2024/01. Molecular Cell, 84 (1) pp. 8-11. Peer-reviewed.
[DOI][Pmid][serval:BIB_DAA33882D6E4]
 
Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions.
Sollier J., Basler M., Broz P., Dittrich P.S., Drescher K., Egli A., Harms A., Hierlemann A., Hiller S., King C.G. et al., 2024/01. Nature microbiology, 9 (1) pp. 1-3. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EB304466645B]
2023
Identification of Tensin-3 as a MALT1 substrate that controls B cell adhesion and lymphoma dissemination.
Juilland M., Alouche N., Ubezzi I., Gonzalez M., Rashid H.O., Scarpellino L., Erdmann T., Grau M., Lenz G., Luther S.A. et al., 2023/12/26. Proceedings of the National Academy of Sciences of the United States of America, 120 (52) pp. e2301155120. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_9C724DAA6D7C]
A Missense Mutation in the Collagen Triple Helix of EDA Is Associated with X-Linked Recessive Hypohidrotic Ectodermal Dysplasia in Fleckvieh Cattle.
Reinartz S., Weiß C., Heppelmann M., Hewicker-Trautwein M., Hellige M., Willen L., Feige K., Schneider P., Distl O., 2023/12/20. Genes, 15 (1) p. 8. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_B9CC7B1AD0C8]
Atg18 oligomer organization in assembled tubes and on lipid membrane scaffolds.
Mann D., Fromm S.A., Martinez-Sanchez A., Gopaldass N., Choy R., Mayer A., Sachse C., 2023/12/06. Nature communications, 14 (1) p. 8086. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EDBF6A5BC653]
 
E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.
Pruenster M., Immler R., Roth J., Kuchler T., Bromberger T., Napoli M., Nussbaumer K., Rohwedder I., Wackerbarth L.M., Piantoni C. et al., 2023/12. Nature immunology, 24 (12) pp. 2021-2031. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_738C3585C874]
 
Gasdermin D is the only Gasdermin that provides protection against acute Salmonella gut infection in mice.
Fattinger S.A., Maurer L., Geiser P., Bernard E.M., Enz U., Ganguillet S., Gül E., Kroon S., Demarco B., Mack V. et al., 2023/11/28. Proceedings of the National Academy of Sciences of the United States of America, 120 (48) pp. e2315503120. Peer-reviewed.
[DOI][Pmid][serval:BIB_5D7AB13847DD]
Non-Hydrolysable Analogues of Cyclic and Branched Condensed Phosphates: Chemistry and Chemical Proteomics.
Dürr-Mayer T., Schmidt A., Wiesler S., Huck T., Mayer A., Jessen H.J., 2023/11/24. Chemistry, 29 (66) pp. e202302400. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F389B5E1C627]
MALT-1 shortens lifespan by inhibiting autophagy in the intestine of C. elegans.
Vérièpe-Salerno J., Podavini S., Long MJC, Kolotuev I., Cuendet M., Thome M., 2023/11/09. Autophagy reports, 2 (1) p. 2277584. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_D6E4081D3FDA]
 
Human interleukin-12α and EBI3 are cytokines with anti-inflammatory functions.
Hildenbrand K., Bohnacker S., Menon P.R., Kerle A., Prodjinotho U.F., Hartung F., Strasser P.C., Catici DAM, Rührnößl F., Haslbeck M. et al., 2023/10/27. Science advances, 9 (43) pp. eadg6874. Peer-reviewed.
[DOI][Pmid][serval:BIB_67C40EE6710B]
A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity
Boeszoermenyi Andras, Bernaleau Léa, Chen Xudong, Kartnig Felix, Xie Min, Zhang Haobo, Zhang Sensen, Delacrétaz Maeva, Koren Anna, Hopp Ann-Katrin et al., 2023/10/20. Nature Communications, 14 (1). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_829247FD8455]
ER-trafficking triggers NRF1 ubiquitination to promote its proteolytic activation.
Chavarria C., Zaffalon L., Ribeiro S.T., Op M., Quadroni M., Iatrou M.S., Chapuis C., Martinon F., 2023/10/20. iScience, 26 (10) p. 107777. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_85F1CAE98072]
Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling
Chen Xudong, Xie Min, Zhang Sensen, Monguió-Tortajada Marta, Yin Jian, Liu Chang, Zhang Youqi, Delacrétaz Maeva, Song Mingyue, Wang Yixue et al., 2023/10/20. Nature Communications, 14 (1). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_DEFB75963887]
 
Androgen receptor is a determinant of melanoma targeted drug resistance.
Samarkina A., Youssef M.K., Ostano P., Ghosh S., Ma M., Tassone B., Proust T., Chiorino G., Levesque M.P., Goruppi S. et al., 2023/10/14. Nature communications, 14 (1) p. 6498. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CD9AA3E3CEE6]
 
Author Correction: Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish.
Huang K.T., Poganik J.R., Parvez S., Raja S., Miller B., Long MJC, Fetcho J.R., Aye Y., 2023/10. Nature protocols, 18 (10) p. 3155. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BD0D0C376F62]
 
Inositol pyrophosphate dynamics reveals control of the yeast phosphate starvation program through 1,5-IP<sub>8</sub> and the SPX domain of Pho81.
Chabert V., Kim G.D., Qiu D., Liu G., Michaillat Mayer L., Jamsheer K M., Jessen H.J., Mayer A., 2023/09/20. eLife, 12. Peer-reviewed.
[DOI][Pmid][serval:BIB_AED4227C0003]
 
POSTER: TCL-330 RHOA G17V Potentiates CD28-Induced NFAT Transcriptional Activity by Modulating p300 Activity: A Step Further in the Understanding of Follicular Helper T-Cell Lymphoma
Vallois David, Juilland Mélanie, Kalliopi Ioannidou, Lemmonier François, Missiaglia Edoardo, Bisig Bettina, Thome Margot, de Leval Laurence, 2023/09. pp. S214 dans Clinical Lymphoma Myeloma and Leukemia, Elsevier BV.
[DOI][serval:BIB_B00CB4F58EB3]
Unconventional protein secretion by gasdermin pores.
Broz P., 2023/09. Seminars in immunology, 69 p. 101811. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_C83DC8D8B0B6]
 
N-Nitrosation Based Fluorescence Turn-On Nitric Oxide Probe: Kinetic and Cell Imaging Studies.
Dutta A., Maiti D., Katarkar A., Sasmal M., Khatun R., Moni D., Habibullah M., Ali M., 2023/08/21. ACS applied bio materials, 6 (8) pp. 3266-3277. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_40F2CB4CCC11]
The mitochondrial succinate dehydrogenase complex controls the STAT3-IL-10 pathway in inflammatory macrophages.
Gobelli D., Serrano-Lorenzo P., Esteban-Amo M.J., Serna J., Pérez-García M.T., Orduña A., Jourdain A.A., Martín-Casanueva M.Á., Á de la Fuente M., Simarro M., 2023/08/18. iScience, 26 (8) p. 107473. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D70FF9529DAB]
 
NLRP12 senses heme and PAMPs to drive necrotic cell death and inflammation.
Bernard E.M., Broz P., 2023/08/03. Molecular cell, 83 (15) pp. 2621-2623. Peer-reviewed.
[DOI][Pmid][serval:BIB_DF61EFC56003]
 
Deep next-generation proteomics and network analysis reveal systemic and tissue-specific patterns in Fabry disease.
Tebani A., Barbey F., Dormond O., Ducatez F., Marret S., Nowak A., Bekri S., 2023/08. Translational research, 258 pp. 47-59. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_60B7F9E411D1]
SLC15A4 controls endolysosomal TLR7–9 responses by recruiting the innate immune adaptor TASL
Zhang Haobo, Bernaleau Léa, Delacrétaz Maeva, Hasanovic Ed, Drobek Ales, Eibel Hermann, Rebsamen Manuele, 2023/08. Cell Reports, 42 (8) p. 112916. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D9B6F053E4A5]
Optogenetic Induction of Pyroptosis, Necroptosis, and Apoptosis in Mammalian Cell Lines.
Shkarina K., Broz P., 2023/07/20. Bio-protocol, 13 (14) pp. e4762. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_CA11157AA004]
 
Features of Isoforms of Human Soluble TACI.
Fichtner M.L., Rübsamen H., Smolle M., Schaller J., Feederle R., Bültmann A., Kümpfel T., Schneider P., Thaler F.S., Meinl E., 2023/07/15. Journal of immunology, 211 (2) pp. 199-208. Peer-reviewed.
[DOI][Pmid][serval:BIB_43B571503FE4]
The Opto-inflammasome in zebrafish as a tool to study cell and tissue responses to speck formation and cell death.
Hasel de Carvalho E., Dharmadhikari S.S., Shkarina K., Xiong J.R., Reversade B., Broz P., Leptin M., 2023/07/07. eLife, 12 pp. e86373. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D9A90FC8CC5C]
The Statistical Analysis of the Varying Brain.
Chén Oliver Y., Thanh Vũ Duy, Greub Gilbert, Cao Hengyi, He Xingru, Muller Yannick, Petrovas Constantinos, Shou Haochang, Nguyen Viet-Dung, Zhi Bangdong et al., 2023/07/02. dans IEEE Statistical Signal Processing (SSP). Peer-reviewed.
[URN][DOI][WoS][serval:BIB_C6B3B6AA1F8B]
 
Myc controls NK cell development, IL-15-driven expansion, and translational machinery.
Khameneh H.J., Fonta N., Zenobi A., Niogret C., Ventura P., Guerra C., Kwee I., Rinaldi A., Pecoraro M., Geiger R. et al., 2023/07. Life science alliance, 6 (7) pp. e202302069. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_79E845E39566]
Metabolic Consequences of Polyphosphate Synthesis and Imminent Phosphate Limitation.
Kim G.D., Qiu D., Jessen H.J., Mayer A., 2023/06/27. mBio, 14 (3) pp. e0010223. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_16840248D4A5]
 
Monitoring On-Target Signaling Responses in Larval Zebrafish - Z-REX Unmasks Precise Mechanisms of Electrophilic Drugs and Metabolites.
Huang K.T., Ly P., Poganik J.R., Parvez S., Long MJC, Aye Y., 2023/06/02. Journal of visualized experiments, 196 pp. e64846. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D9C4F5AB9756]
 
Two-Step Tag-Free Isolation of Mitochondria for Improved Protein Discovery and Quantification.
Blanco-Fernandez J., Jourdain A.A., 2023/06/02. Journal of visualized experiments 196. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F177E8CF7E60]
Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A).
Brauer N., Maruta Y., Lisci M., Strege K., Oschlies I., Nakamura H., Böhm S., Lehmberg K., Brandhoff L., Ehl S. et al., 2023/06. Frontiers in immunology, 14 p. 1151166. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3A88D15E3584]
Structural basis of NINJ1-mediated plasma membrane rupture in cell death.
Degen M., Santos J.C., Pluhackova K., Cebrero G., Ramos S., Jankevicius G., Hartenian E., Guillerm U., Mari S.A., Kohl B. et al., 2023/06. Nature, 618 (7967) pp. 1065-1071. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EC6DA0B4AD39]
Turing's turtles all the way down: A conserved role of EDAR in the carapacial ridge suggests a deep homology of prepatterns across ectodermal appendages.
Zimm R., Oberdick D., Gnetneva A., Schneider P., Cebra-Thomas J., Moustakas-Verho J.E., 2023/06. Anatomical record, 306 (6) pp. 1201-1213. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ADBB3F81DBEA]
Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions.
Skinner O.S., Blanco-Fernández J., Goodman R.P., Kawakami A., Shen H., Kemény L.V., Joesch-Cohen L., Rees M.G., Roth J.A., Fisher D.E. et al., 2023/05/17. Nature metabolism. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_A1A6C5A94F05]
Cryo-EM structure of the polyphosphate polymerase VTC reveals coupling of polymer synthesis to membrane transit.
Liu W., Wang J., Comte-Miserez V., Zhang M., Yu X., Chen Q., Jessen H.J., Mayer A., Wu S., Ye S., 2023/05/15. The EMBO journal, 42 (10) pp. e113320. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D34341B6BEB1]
Inositol pyrophosphates activate the vacuolar transport chaperone complex in yeast by disrupting a homotypic SPX domain interaction.
Pipercevic J., Kohl B., Gerasimaite R., Comte-Miserez V., Hostachy S., Müntener T., Agustoni E., Jessen H.J., Fiedler D., Mayer A. et al., 2023/05/08. Nature communications, 14 (1) p. 2645. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A3106DB32252]
 
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Vitale I., Pietrocola F., Guilbaud E., Aaronson S.A., Abrams J.M., Adam D., Agostini M., Agostinis P., Alnemri E.S., Altucci L. et al., 2023/05. Cell death and differentiation, 30 (5) pp. 1097-1154. Peer-reviewed.
[DOI][Pmid][serval:BIB_5886312BEF39]
ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages.
Aylan B., Bernard E.M., Pellegrino E., Botella L., Fearns A., Athanasiadi N., Bussi C., Santucci P., Gutierrez M.G., 2023/05. Nature microbiology, 8 (5) pp. 803-818. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F452BB2C0D26]
Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells.
Corria-Osorio J., Carmona S.J., Stefanidis E., Andreatta M., Ortiz-Miranda Y., Muller T., Rota I.A., Crespo I., Seijo B., Castro W. et al., 2023/05. Nature immunology, 24 (5) pp. 869-883. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B6529135A8DD]
 
Revisiting autoimmune lymphoproliferative syndrome caused by Fas ligand mutations.
Maccari M.E., Schneider P., Smulski C.R., Meinhardt A., Pinto F., Gonzalez-Granado L.I., Schuetz C., Sica M.P., Gross M., Fuchs I. et al., 2023/05. The Journal of allergy and clinical immunology, 151 (5) pp. 1391-1401.e7. Peer-reviewed.
[DOI][Pmid][serval:BIB_8EE6CA3E96F5]
 
Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish.
Huang K.T., Poganik J.R., Parvez S., Raja S., Miller B., Long MJC, Fetcho J.R., Aye Y., 2023/05. Nature protocols, 18 (5) pp. 1379-1415. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_FE6B92D5DC45]
 
Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction.
Sülzen H., Began J., Dhillon A., Kereïche S., Pompach P., Votrubova J., Zahedifard F., Šubrtova A., Šafner M., Hubalek M. et al., 2023/04/27. Nature communications, 14 (1) p. 2403. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4E9CB7BFD528]
A Causal Treatment for X-Linked Hypohidrotic Ectodermal Dysplasia: Long-Term Results of Short-Term Perinatal Ectodysplasin A1 Replacement.
Schneider H., Schweikl C., Faschingbauer F., Hadj-Rabia S., Schneider P., 2023/04/12. International journal of molecular sciences, 24 (8) p. 7155. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_55995EB323AC]
 
SHP-1 localization to the activating immune synapse promotes NK cell tolerance in MHC class I deficiency.
Schmied L., Luu T.T., Søndergaard J.N., Hald S.H., Meinke S., Mohammad D.K., Singh S.B., Mayer C., Perinetti Casoni G., Chrobok M. et al., 2023/04/11. Science signaling, 16 (780) pp. eabq0752. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F38A463DE9C1]
The alarmin interleukin-33 promotes the expansion and preserves the stemness of Tcf-1+ CD8+ T cells in chronic viral infection.
Marx A.F., Kallert S.M., Brunner T.M., Villegas J.A., Geier F., Fixemer J., Abreu-Mota T., Reuther P., Bonilla W.V., Fadejeva J. et al., 2023/04/11. Immunity, 56 (4) pp. 813-828.e10. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_796365D38E1A]
 
Gasdermin D membrane pores orchestrate IL-1α secretion from necrotic macrophages after NFS-rich silica exposure.
Leinardi R., Pochet A., Uwambayinema F., Yakoub Y., Quesniaux V., Ryffel B., Broz P., Pavan C., Huaux F., 2023/04. Archives of toxicology, 97 (4) pp. 1001-1015. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F76FD63F5D54]
The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages.
Maier A.M., Huth K., Alessandrini F., Schnautz B., Arifovic A., Riols F., Haid M., Koegler A., Sameith K., Schmidt-Weber C.B. et al., 2023/04. Frontiers in immunology, 14 p. 1157373. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1651B34FF194]
SLC15A4 controls endolysosomal TLR7-9 responses by recruiting the innate immune adaptor TASL
Haobo Zhang, Léa Bernaleau, Maeva Delacrétaz, Ed Hasanovic, Hermann Eibel, Manuele Rebsamen, 2023/03/27..
[URN][DOI][serval:BIB_DE91D1D2BC15]
 
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK-STAT endosomal activation.
Zanin N., Viaris de Lesegno C., Podkalicka J., Meyer T., Gonzalez Troncoso P., Bun P., Danglot L., Chmiest D., Urbé S., Piehler J. et al., 2023/03. Nature cell biology, 25 (3) pp. 425-438. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_768239062C87]
The ULK3 kinase is a determinant of keratinocyte self-renewal and tumorigenesis targeting the arginine methylome.
Goruppi S., Clocchiatti A., Bottoni G., Di Cicco E., Ma M., Tassone B., Neel V., Demehri S., Simon C., Paolo Dotto G., 2023/02/16. Nature communications, 14 (1) p. 887. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ACC0B5090E58]
CVID-Associated B Cell Activating Factor Receptor Variants Change Receptor Oligomerization, Ligand Binding, and Signaling Responses.
Block V., Sevdali E., Recher M., Abolhassani H., Hammarstrom L., Smulski C.R., Baronio M., Plebani A., Proietti M., Speletas M. et al., 2023/02. Journal of clinical immunology, 43 (2) pp. 391-405. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2DE9DC2406E5]
Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction.
Gopaldass N., De Leo M.G., Courtellemont T., Mercier V., Bissig C., Roux A., Mayer A., 2023/01/16. The EMBO journal, 42 (2) pp. e112287. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_92879E1C5BC4]
Molecular insights into sex-specific metabolic alterations in Alzheimer's mouse brain using multi-omics approach.
Strefeler A., Jan M., Quadroni M., Teav T., Rosenberg N., Chatton J.Y., Guex N., Gallart-Ayala H., Ivanisevic J., 2023/01/09. Alzheimer's research & therapy, 15 (1) p. 8. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5426CE38C858]
Protein kinase B (AKT) upregulation and Thy-1-α<sub>v</sub>β<sub>3</sub> integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis.
Pérez-Núñez R., Chamorro A., González M.F., Contreras P., Artigas R., Corvalán A.H., van Zundert B., Reyes C., Moya P.R., Avalos A.M. et al., 2023/01/06. Journal of neuroinflammation, 20 (1) p. 5. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9764A8B87F3E]
 
Caspase-4 Activation and Recruitment to Intracellular Gram-Negative Bacteria
Dilucca Marisa, Broz Petr, 2023. pp. 49-65 dans Pyroptosis, Springer US.
[DOI][Pmid][serval:BIB_E522DEB8F2BC]
Corrigendum: The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages.
Maier A.M., Huth K., Alessandrini F., Henkel F., Schnautz B., Arifovic A., Riols F., Haid M., Koegler A., Sameith K. et al., 2023. Frontiers in immunology, 14 p. 1221064. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CF93C640E8E4]
 
Dead-Seq: Discovering Synthetic Lethal Interactions from Dead Cells Genomics.
Blanco-Fernandez J., Jourdain A.A., 2023. pp. 329-342 dans The Mitoribosome, Springer.
[URN][DOI][Pmid][serval:BIB_F76D5A9A3A60]
NLRP3 leucine-rich repeats control induced and spontaneous inflammasome activation in cryopyrin-associated periodic syndrome.
Theodoropoulou K., Spel L., Zaffalon L., Delacrétaz M., Hofer M., Martinon F., 2023/01. The Journal of allergy and clinical immunology, 151 (1) pp. 222-232.e9. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17138F05CB5E]
2022
c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs.
González-Loyola A., Bernier-Latmani J., Roci I., Wyss T., Langer J., Durot S., Munoz O., Prat-Luri B., Delorenzi M., Lutolf M.P. et al., 2022/12/05. The Journal of experimental medicine, 219 (12) pp. e20212418. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0333000E22CD]
Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism.
Bussi C., Heunis T., Pellegrino E., Bernard E.M., Bah N., Dos Santos M.S., Santucci P., Aylan B., Rodgers A., Fearns A. et al., 2022/11/28. Nature communications, 13 (1) p. 7338. Peer-reviewed.
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A Multi-Omics Approach Reveals Features That Permit Robust and Widespread Regulation of IFN-Inducible Antiviral Effectors.
Göczi L., Csumita M., Horváth A., Nagy G., Póliska S., Pigni M., Thelemann C., Dániel B., Mianesaz H., Varga T. et al., 2022/11/15. Journal of immunology, 209 (10) pp. 1930-1941. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3B0568108815]
CDC42 regulates PYRIN inflammasome assembly.
Spel L., Zaffalon L., Hou C., Nganko N., Chapuis C., Martinon F., 2022/11/15. Cell reports, 41 (7) p. 111636. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_8264D9307A8A]
Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses.
Ventura PMO, Gakovic M., Fischer B.A., Spinelli L., Rota G., Pathak S., Khameneh H.J., Zenobi A., Thomson S., Birchmeier W. et al., 2022/11/07. EMBO reports, 23 (11) pp. e55399. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_897F77319631]
Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions.
Rebsamen M., Girardi E., Sedlyarov V., Scorzoni S., Papakostas K., Vollert M., Konecka J., Guertl B., Klavins K., Wiedmer T. et al., 2022/11. Life science alliance, 5 (11) pp. e202201404. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_ECC63CD3FA4B]
Z-REX uncovers a bifurcation in function of Keap1 paralogs.
Van Hall-Beauvais A., Poganik J.R., Huang K.T., Parvez S., Zhao Y., Lin H.Y., Liu X., Long MJC, Aye Y., 2022/10/27. eLife, 11. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A37FCE8471AE]
The protease DDI2 regulates NRF1 activation in response to cadmium toxicity.
Ribeiro S.T., de Gassart A., Bettigole S., Zaffalon L., Chavarria C., Op M., Nugraha K., Martinon F., 2022/10/21. iScience, 25 (10) p. 105227. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_F504A8AA7323]
 
Hitting the Bullseye: Endogenous Electrophiles Show Remarkable Nuance in Signaling Regulation.
Long MJC, Miranda Herrera P.A., Aye Y., 2022/10/17. Chemical research in toxicology, 35 (10) pp. 1636-1648. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E8A277D9440C]
 
Mesenchymal cells in health and disease.
Koliaraki V., Dotto G.P., Buckley C.D., Kollias G., 2022/10. Nature immunology, 23 (10) pp. 1395-1398. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C6C936B6B935]
Multitier mechanics control stromal adaptations in the swelling lymph node.
Assen F.P., Abe J., Hons M., Hauschild R., Shamipour S., Kaufmann W.A., Costanzo T., Krens G., Brown M., Ludewig B. et al., 2022/08. Nature immunology, 23 (8) pp. 1246-1255. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F80AA3E25D81]
ADAMTS18<sup>+</sup> villus tip telocytes maintain a polarized VEGFA signaling domain and fenestrations in nutrient-absorbing intestinal blood vessels.
Bernier-Latmani J., Mauri C., Marcone R., Renevey F., Durot S., He L., Vanlandewijck M., Maclachlan C., Davanture S., Zamboni N. et al., 2022/07/09. Nature communications, 13 (1) p. 3983. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AC4B62DD6AED]
BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors.
Sevdali E., Block V., Lataretu M., Li H., Smulski C.R., Briem J.S., Heitz Y., Fischer B., Ramirez N.J., Grimbacher B. et al., 2022/06/28. Cell reports, 39 (13) p. 111019. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_13E73B5B8C0A]
Sialic acids on B cells are crucial for their survival and provide protection against apoptosis.
Linder A.T., Schmidt M., Hitschfel J., Abeln M., Schneider P., Gerardy-Schahn R., Münster-Kühnel A.K., Nitschke L., 2022/06/21. Proceedings of the National Academy of Sciences of the United States of America, 119 (25) pp. e2201129119. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8C01245BEAE4]
 
Hiding in Plain Sight: The Issue of Hidden Variables.
Long MJC, Assari M., Aye Y., 2022/06/17. ACS chemical biology, 17 (6) pp. 1285-1292. Peer-reviewed.
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IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease.
Dwyer G.K., Mathews L.R., Villegas J.A., Lucas A., Gonzalez de Peredo A., Blazar B.R., Girard J.P., Poholek A.C., Luther S.A., Shlomchik W. et al., 2022/06/15. Journal of clinical investigation, 132 (12) pp. e150927. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9A7DBCB96AD9]
 
Optogenetic activators of apoptosis, necroptosis, and pyroptosis.
Shkarina K., Hasel de Carvalho E., Santos J.C., Ramos S., Leptin M., Broz P., 2022/06/06. The Journal of cell biology, 221 (6) pp. e202109038. Peer-reviewed.
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LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.
Bombaci G., Sarangdhar M.A., Andina N., Tardivel A., Yu E.C., Mackie G.M., Pugh M., Ozan V.B., Banz Y., Spinetti T. et al., 2022/06. Life science alliance, 5 (6) pp. e202101226. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4E57CCCF79FA]
 
Viral protein activates the NLRP1 inflammasome.
Hartenian E., Broz P., 2022/06. Nature immunology, 23 (6) pp. 822-824. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_21857F591F35]
Paired guide RNA CRISPR-Cas9 screening for protein-coding genes and lncRNAs involved in transdifferentiation of human B-cells to macrophages.
Arnan C., Ullrich S., Pulido-Quetglas C., Nurtdinov R., Esteban A., Blanco-Fernandez J., Aparicio-Prat E., Johnson R., Pérez-Lluch S., Guigó R., 2022/05/26. BMC genomics, 23 (1) p. 402. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_64A29905BC65]
The aspartyl protease DDI2 drives adaptation to proteasome inhibition in multiple myeloma.
Op M., Ribeiro S.T., Chavarria C., De Gassart A., Zaffalon L., Martinon F., 2022/05/19. Cell death & disease, 13 (5) p. 475. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A9FBE08A94DB]
CROP: a retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system.
Courtellemont T., De Leo M.G., Gopaldass N., Mayer A., 2022/05/16. The EMBO journal, 41 (10) pp. e109646. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4BA5CFC52331]
 
The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis.
Prat-Luri B., Neal C., Passelli K., Ganga E., Amore J., Firmino-Cruz L., Petrova T.V., Müller A.J., Tacchini-Cottier F., 2022/05/03. Cell reports, 39 (5) p. 110777. Peer-reviewed.
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Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth.
Bernier-Latmani J., Cisarovsky C., Mahfoud S., Ragusa S., Dupanloup I., Barras D., Renevey F., Nassiri S., Anderle P., Squadrito M.L. et al., 2022/05. Nature cardiovascular research, 1 (5) pp. 476-490. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_998EFE1BCFC2]
Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis.
Santucci P., Aylan B., Botella L., Bernard E.M., Bussi C., Pellegrino E., Athanasiadi N., Gutierrez M.G., 2022/04/26. mBio, 13 (2) pp. e0011722. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_573CEB9F687C]
 
Sphingolipids control dermal fibroblast heterogeneity.
Capolupo L., Khven I., Lederer A.R., Mazzeo L., Glousker G., Ho S., Russo F., Montoya J.P., Bhandari D.R., Bowman A.P. et al., 2022/04/15. Science, 376 (6590) pp. eabh1623. Peer-reviewed.
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Activation and manipulation of inflammasomes and pyroptosis during bacterial infections.
Bernard E.M., Broz P., 2022/04/14. The Biochemical journal, 479 (7) pp. 867-882. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F5EFACC64C78]
 
Can Precision Electrophile Signaling Make a Meaningful and Lasting Impression in Drug Design?
Long MJC, Kulkarni A., Aye Y., 2022/04/05. Chembiochem, 23 (7) pp. e202100051. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2F8FF3DF77CA]
Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells.
Smulski C.R., Zhang L., Burek M., Teixidó Rubio A., Briem J.S., Sica M.P., Sevdali E., Vigolo M., Willen L., Odermatt P. et al., 2022/03/29. Cell reports, 38 (13) p. 110583. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BF01BC2683F0]
 
The Dangerous Liaisons in the Oxidative Stress Response to Leishmania Infection.
Reverte M., Snäkä T., Fasel N., 2022/03/28. Pathogens, 11 (4) p. 409. Peer-reviewed.
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Randomized clinical trial to assess the protective efficacy of a Plasmodium vivax CS synthetic vaccine.
Arévalo-Herrera M., Gaitán X., Larmat-Delgado M., Caicedo M.A., Herrera S.M., Henao-Giraldo J., Castellanos A., Devaud J.C., Pannatier A., Oñate J. et al., 2022/03/25. Nature communications, 13 (1) p. 1603. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D09811DF074D]
Stem-cell-like T cells have a specific entry gate to the tumor.
Held W., Luther S.A., Petrova T.V., 2022/03/14. Cancer cell, 40 (3) pp. 243-245. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_51451730613C]
The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa.
Del-Pozo J., Headon D.J., Glover J.D., Azar A., Schuepbach-Mallepell S., Bhutta M.F., Riddell J., Maxwell S., Milne E., Schneider P. et al., 2022/03/01. Disease models & mechanisms, 15 (3) pp. dmm049034. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A41FC1BA53F1]
 
Regulation of Lytic and Non-Lytic Functions of Gasdermin Pores.
Rühl S., Broz P., 2022/02/28. Journal of molecular biology, 434 (4) p. 167246. Peer-reviewed.
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Function-guided proximity mapping unveils electrophilic-metabolite sensing by proteins not present in their canonical locales.
Zhao Y., Miranda Herrera P.A., Chang D., Hamelin R., Long MJC, Aye Y., 2022/02/01. Proceedings of the National Academy of Sciences of the United States of America, 119 (5) pp. e2120687119. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_87675A2929BB]
 
Immunogenicity of full-length P. vivax rPvs48/45 protein formulations in BALB/c mice.
Arévalo-Herrera M., Miura K., Solano E., Sebastián Ramírez J., Long C.A., Corradin G., Herrera S., 2022/01/03. Vaccine, 40 (1) pp. 133-140. Peer-reviewed.
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A SARS-CoV-2 Spike Receptor Binding Motif Peptide Induces Anti-Spike Antibodies in Mice andIs Recognized by COVID-19 Patients.
Pratesi F., Errante F., Pacini L., Peña-Moreno I.C., Quiceno S., Carotenuto A., Balam S., Konaté D., Diakité M.M., Arévalo-Herrera M. et al., 2022. Frontiers in immunology, 13 p. 879946. Peer-reviewed.
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Bartonella taylorii: A Model Organism for Studying Bartonella Infection in vitro and in vivo.
Fromm K., Boegli A., Ortelli M., Wagner A., Bohn E., Malmsheimer S., Wagner S., Dehio C., 2022. Frontiers in microbiology, 13 p. 913434. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5FCFF189366A]
 
Cigarette smoke-induced gasdermin D activation in bronchoalveolar macrophages and bronchial epithelial cells dependently on NLRP3.
Huot-Marchand S., Nascimento M., Culerier E., Bourenane M., Savigny F., Panek C., Serdjebi C., Le Bert M., Quesniaux VFJ, Ryffel B. et al., 2022. Frontiers in immunology, 13 p. 918507. Peer-reviewed.
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Detection of Gasdermin Activation and Lytic Cell Death During Pyroptosis and Apoptosis
Demarco Benjamin, Ramos Saray, Broz Petr, 2022. pp. 209-237 dans Effector-Triggered Immunity, Springer.
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Dissection of the macrophage response towards infection by the Leishmania-viral endosymbiont duo and dynamics of the type I interferon response.
Bekkar A., Isorce N., Snäkä T., Claudinot S., Desponds C., Kopelyanskiy D., Prével F., Reverte M., Xenarios I., Fasel N. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 941888. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8E5B725F389C]
 
Functional and clinical analysis of five EDA variants associated with ectodermal dysplasia but with a hard-to-predict significance.
Gökdere S., Schneider H., Hehr U., Willen L., Schneider P., Maier-Wohlfart S., 2022. Frontiers in genetics, 13 p. 934395. Peer-reviewed.
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In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells.
Jha B., Reverte M., Ronet C., Prevel F., Morgenthaler F.D., Desponds C., Lye L.F., Owens K.L., Scarpellino L., Dubey L.K. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 941860. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2B104E1E8C7E]
Kinetics of free and ligand-bound atacicept in human serum.
Eslami M., Willen D., Papasouliotis O., Schuepbach-Mallpell S., Willen L., Donzé O., Yalkinoglu Ö., Schneider P., 2022. Frontiers in immunology, 13 p. 1035556. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_ADE61E899086]
Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont.
Kopelyanskiy D., Desponds C., Prevel F., Rossi M., Migliorini R., Snäkä T., Eren R.O., Claudinot S., Lye L.F., Pasparakis M. et al., 2022. Frontiers in cellular and infection microbiology, 12 p. 944819. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A72D8B03FFC4]
 
Seroreactivity of the Severe Acute Respiratory Syndrome Coronavirus 2 Recombinant S Protein, Receptor-Binding Domain, and Its Receptor-Binding Motif in COVID-19 Patients and Their Cross-Reactivity With Pre-COVID-19 Samples From Malaria-Endemic Areas.
Traoré A., Guindo M.A., Konaté D., Traoré B., Diakité S.A., Kanté S., Dembélé A., Cissé A., Incandela N.C., Kodio M. et al., 2022. Frontiers in immunology, 13 p. 856033. Peer-reviewed.
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Sex-Biased Control of Inflammation and Metabolism by a Mitochondrial Nod-Like Receptor.
Snäkä T., Bekkar A., Desponds C., Prével F., Claudinot S., Isorce N., Teixeira F., Grasset C., Xenarios I., Lopez-Mejia I.C. et al., 2022. Frontiers in immunology, 13 p. 882867. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6C22CA5A408C]
 
SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.
Jha A., Ahad A., Mishra G.P., Sen K., Smita S., Minz A.P., Biswas V.K., Tripathy A., Senapati S., Gupta B. et al., 2022. Frontiers in immunology, 13 p. 910705. Peer-reviewed.
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Still no Rest for the Reductases: Ribonucleotide Reductase (RNR) Structure and Function: An Update
Long Marcus J. C., Ly Phillippe, Aye Yimon, 2022. pp. 155-197 dans Macromolecular Protein Complexes IV: Structure and Function chap. 5, Springer International Publishing.
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The c-MET receptor tyrosine kinase contributes to neutrophil-driven pathology in cutaneous leishmaniasis.
Passelli K., Prat-Luri B., Merlot M., Goris M., Mazzone M., Tacchini-Cottier F., 2022/01. PLoS pathogens, 18 (1) pp. e1010247. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F09B4A0D524F]
2021
Receptor Activator of NF-κB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course.
Clar K.L., Weber L.M., Schmied B.J., Heitmann J.S., Marconato M., Tandler C., Schneider P., Salih H.R., 2021/12/04. Cancers, 13 (23) p. 6122. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B23D9F7E88BF]
ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma.
Sartori G., Napoli S., Cascione L., Chung EYL, Priebe V., Arribas A.J., Mensah A.A., Dall'Angelo M., Falzarano C., Barnabei L. et al., 2021/11/11. Journal of experimental & clinical cancer research, 40 (1) p. 357. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EA8A538A1370]
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity.
Di Conza G., Tsai C.H., Gallart-Ayala H., Yu Y.R., Franco F., Zaffalon L., Xie X., Li X., Xiao Z., Raines L.N. et al., 2021/11. Nature immunology, 22 (11) pp. 1403-1415. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_38FF542D6B24]
WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms.
De Leo M.G., Berger P., Mayer A., 2021/11. Autophagy, 17 (11) pp. 3644-3670. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5C79F12FE465]
 
The Card19 locus of murine chromosome 13 regulates terminal cell lysis downstream of caspase activation and Gasdermin-D cleavage
Bjanes Elisabet, Sillas Reyna Garcia, Matsuda Rina, Demarco Benjamin, Fettrelet Timothée, DeLaney Alexandra A., Rodriguez Lopez Eric M., Grubaugh Daniel, Wynosky-Dolfi Meghan A., Philip Naomi H. et al., 2021/10/21..
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Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Bjanes E., Sillas R.G., Matsuda R., Demarco B., Fettrelet T., DeLaney A.A., Kornfeld O.S., Lee B.L., Rodríguez López E.M., Grubaugh D. et al., 2021/10. PLoS pathogens, 17 (10) pp. e1009967. Peer-reviewed.
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HOPX Exhibits Oncogenic Activity during Squamous Skin Carcinogenesis.
Pavlova O., Lefort K., Mariotto A., Huber M., Hohl D., 2021/10. The Journal of investigative dermatology, 141 (10) pp. 2354-2368. Peer-reviewed.
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Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera.
Poganik J.R., Huang K.T., Parvez S., Zhao Y., Raja S., Long MJC, Aye Y., 2021/09/30. Nature communications, 12 (1) p. 5736. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DF7A04D809CC]
The chemistry of branched condensed phosphates.
Dürr-Mayer T., Qiu D., Eisenbeis V.B., Steck N., Häner M., Hofer A., Mayer A., Siegel J.S., Baldridge K.K., Jessen H.J., 2021/09/10. Nature communications, 12 (1) p. 5368. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C3FB7908B34E]
Guanylate-Binding Protein-Dependent Noncanonical Inflammasome Activation Prevents Burkholderia thailandensis-Induced Multinucleated Giant Cell Formation.
Dilucca M., Ramos S., Shkarina K., Santos J.C., Broz P., 2021/08/31. mBio, 12 (4) pp. e0205421. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_78967419823A]
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
Tsiantoulas D., Eslami M., Obermayer G., Clement M., Smeets D., Mayer F.J., Kiss M.G., Enders L., Weißer J., Göderle L. et al., 2021/08/25. Nature, 597 (7874) pp. 92-96. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_17F331130FAD]
 
Science's Response to CoVID-19.
Long MJC, Aye Y., 2021/08/05. ChemMedChem, 16 (15) pp. 2288-2314. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_701AB75CC3E9]
Function, occurrence and inhibition of different forms of BAFF.
Eslami M., Schneider P., 2021/08. Current opinion in immunology, 71 pp. 75-80. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_537525B04EE5]
Early onset effects of single substrate accumulation recapitulate major features of LSD in patient-derived lysosomes.
Scerra G., De Pasquale V., Pavone L.M., Caporaso M.G., Mayer A., Renna M., D'Agostino M., 2021/07/23. iScience, 24 (7) p. 102707. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1BF329C273C5]
Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING.
Bruand M., Barras D., Mina M., Ghisoni E., Morotti M., Lanitis E., Fahr N., Desbuisson M., Grimm A., Zhang H. et al., 2021/07/20. Cell reports, 36 (3) p. 109412. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_745449157CA6]
 
RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling.
Chen K.W., Demarco B., Ramos S., Heilig R., Goris M., Grayczyk J.P., Assenmacher C.A., Radaelli E., Joannas L.D., Henao-Mejia J. et al., 2021/07/13. Proceedings of the National Academy of Sciences of the United States of America, 118 (28) p. 34260403. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_595417C2F004]
HSD17B7 gene in self-renewal and oncogenicity of keratinocytes from Black versus White populations.
Xu X., Tassone B., Ostano P., Katarkar A., Proust T., Joseph J.M., Riganti C., Chiorino G., Kutalik Z., Lefort K. et al., 2021/07/07. EMBO molecular medicine, 13 (7) pp. e14133. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DFE1A4AC1B94]
FOXC2 controls adult lymphatic endothelial specialization, function, and gut lymphatic barrier preventing multiorgan failure.
González-Loyola A., Bovay E., Kim J., Lozano T.W., Sabine A., Renevey F., Arroz-Madeira S., Rapin A., Wypych T.P., Rota G. et al., 2021/07. Science advances, 7 (29) pp. eabf4335. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3852082D8787]
 
The Enigma of Eosinophil Degranulation.
Fettrelet T., Gigon L., Karaulov A., Yousefi S., Simon H.U., 2021/06/30. International journal of molecular sciences, 22 (13) p. 7091. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9A1E04669CAC]
Chronic Nonbacterial Osteomyelitis in Children.
Koryllou A., Mejbri M., Theodoropoulou K., Hofer M., Carlomagno R., 2021/06/25. Children, 8 (7) p. 551. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A8B79693AA8A]
 
Salvage of Ribose from Uridine or RNA Supports Glycolysis when Glucose is Limiting
Jourdain Alexis A., Skinner Owen S., Kawakami Akinori, Goodman Russel P., Shen Hongying, Kemény Lajos V., Joesch-Cohen Lena, Rees Matthew G., Roth Jennifer A., Fisher David E. et al., 2021/06/10..
[DOI][serval:BIB_ADF94CCF237A]
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
Jourdain A.A., Begg B.E., Mick E., Shah H., Calvo S.E., Skinner O.S., Sharma R., Blue S.M., Yeo G.W., Burge C.B. et al., 2021/05/06. Molecular cell, 81 (9) pp. 1905-1919.e12. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B6C4CA41CF54]
 
Zbtb10 transcription factor is crucial for murine cDC1 activation and cytokine secretion.
Smita S., Ghosh A., Biswas V.K., Ahad A., Podder S., Jha A., Sen K., Acha-Orbea H., Raghav S.K., 2021/05. European journal of immunology, 51 (5) pp. 1126-1142. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_40DDE80854B5]
Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics.
Serrano-Lopez J., Hegde S., Kumar S., Serrano J., Fang J., Wellendorf A.M., Roche P.A., Rangel Y., Carrington L.J., Geiger H. et al., 2021/04/08. eLife, 10 pp. e66190. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_95B2C7F1BB21]
 
The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism
Reverte Marta, Eren Remzi Onur, Jha Baijayanti, Desponds Chantal, Snäkä Tiia, Prevel Florence, Isorce Nathalie, Lye Lon-Fye, Owens Katherine L., Gazos Lopes Ulisses et al., 2021/03/25. PLOS Pathogens, 17 (3) pp. e1009422.
[DOI][WoS][Pmid][serval:BIB_0AB06B72AE21]
 
Active membrane rupture spurs a range of cell deaths.
Hiller S., Broz P., 2021/03/08. Nature, 591 (7848) pp. 36-37. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2B6721A8AAE8]
 
Flash forward genetics: new twists in transcription across evolutionary boundaries.
Dotto G.P., Missero C., 2021/03/03. EMBO reports, 22 (3) pp. e52152. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_DE24BEADFDEC]
 
IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression
Koga Marianna M., Engel Adrien, Pigni Matteo, Lavanchy Christine, Stevanin Mathias, Laversenne Vanessa, Schneider Bernard L., Acha-Orbea Hans, 2021/02/17. Frontiers in Immunology, 12 p. 607315. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_505F034B5FD7]
 
Human primed ILCPs support endothelial activation through NF-κB signaling.
Vanoni G., Ercolano G., Candiani S., Rutigliani M., Lanata M., Derré L., Marcenaro E., Schneider P., Romero P., Jandus C. et al., 2021/02/08. eLife, 10 pp. e58838. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1C654EDB478E]
 
The Immunogenicity of Capsid-Like Particle Vaccines in Combination with Different Adjuvants Using Different Routes of Administration.
Janitzek C.M., Carlsen PHR, Thrane S., Khanna V.M., Jakob V., Barnier-Quer C., Collin N., Theander T.G., Salanti A., Nielsen M.A. et al., 2021/02/06. Vaccines, 9 (2) p. 131. Peer-reviewed.
[DOI][Pmid][serval:BIB_CE60DB3C2400]
 
Nanotechnological immunoassay for rapid label-free analysis of candidate malaria vaccines.
Brunetti G., Padovani F., De Pastina A., Rotella C., Monahan A., Hoffman S.L., Jongo S.A., Abdulla S., Corradin G., Pluschke G. et al., 2021/02/04. Nanoscale, 13 (4) pp. 2338-2349. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0654E4F1C612]
The Release Kinetics of Eosinophil Peroxidase and Mitochondrial DNA Is Different in Association with Eosinophil Extracellular Trap Formation.
Germic N., Fettrelet T., Stojkov D., Hosseini A., Horn M.P., Karaulov A., Simon D., Yousefi S., Simon H.U., 2021/02/03. Cells, 10 (2) p. 306. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B2860403C015]
A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS.
Maccari M.E., Fuchs S., Kury P., Andrieux G., Völkl S., Bengsch B., Lorenz M.R., Heeg M., Rohr J., Jägle S. et al., 2021/02/01. The Journal of experimental medicine, 218 (2) pp. e20192191. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_95F798FD2EB3]
Detection of viruses by inflammasomes.
Spel L., Martinon F., 2021/02. Current opinion in virology, 46 pp. 59-64. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_72676FF55EC7]
Immune responses induced by inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine in neonatal pigs using different adjuvants.
Vreman S., Stockhofe-Zurwieden N., Popma-de Graaf D.J., Savelkoul HFJ, Barnier-Quer C., Collin N., Collins D., McDaid D., Moore A.C., Rebel JMJ, 2021/02. Veterinary immunology and immunopathology, 232 p. 110170. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B0A4D4915183]
Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis.
Ma M., Ghosh S., Tavernari D., Katarkar A., Clocchiatti A., Mazzeo L., Samarkina A., Epiney J., Yu Y.R., Ho P.C. et al., 2021/02/01. The Journal of experimental medicine, 218 (2) pp. e20201137. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3B2A745CA757]
NLRC5 promotes transcription of BTN3A1-3 genes and Vγ9Vδ2 T cell-mediated killing.
Dang A.T., Strietz J., Zenobi A., Khameneh H.J., Brandl S.M., Lozza L., Conradt G., Kaufmann SHE, Reith W., Kwee I. et al., 2021/01/22. iScience, 24 (1) p. 101900. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D5965E9EA8CF]
Dormant Tumor Cell Vaccination: A Mathematical Model of Immunological Dormancy in Triple-Negative Breast Cancer.
Mehdizadeh R., Shariatpanahi S.P., Goliaei B., Peyvandi S., Rüegg C., 2021/01/11. Cancers, 13 (2) p. 245. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BDD03A29D317]
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
Rath Sneha, Sharma Rohit, Gupta Rahul, Ast Tslil, Chan Connie, Durham Timothy J, Goodman Russell P, Grabarek Zenon, Haas Mary E, Hung Wendy H W et al., 2021/01/08. Nucleic Acids Research, 49 (D1) pp. D1541-D1547. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_244FB48E384A]
An Outside-In Switch in Integrin Signaling Caused by Chemical and Mechanical Signals in Reactive Astrocytes.
Pérez L.A., Rashid A., Combs J.D., Schneider P., Rodríguez A., Salaita K., Leyton L., 2021. Frontiers in cell and developmental biology, 9 p. 712627. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BF35D6F2FD14]
 
ASC Speck Formation after Inflammasome Activation in Primary Human Keratinocytes.
Smatlik N., Drexler S.K., Burian M., Röcken M., Yazdi A.S., 2021. Oxidative medicine and cellular longevity, 2021 p. 7914829. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BE1EAA418ABA]
Correction of Vertebral Bone Development in Ectodysplasin A1-Deficient Mice by Prenatal Treatment With a Replacement Protein.
Kossel C.S., Wahlbuhl M., Schuepbach-Mallepell S., Park J., Kowalczyk-Quintas C., Seeling M., von der Mark K., Schneider P., Schneider H., 2021. Frontiers in genetics, 12 p. 709736. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_AD5C7AC2180B]
Editorial: The Skin Immune Response to Infectious Agents.
Conceição-Silva F., Morgado F.N., Pinheiro R.O., Tacchini-Cottier F., 2021. Frontiers in immunology, 12 p. 810059. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1F4093785C84]
 
Fibroblast-derived IL-33 is dispensable for lymph node homeostasis but critical for CD8 T-cell responses to acute and chronic viral infection.
Aparicio-Domingo P., Cannelle H., Buechler M.B., Nguyen S., Kallert S.M., Favre S., Alouche N., Papazian N., Ludewig B., Cupedo T. et al., 2021/01. European journal of immunology, 51 (1) pp. 76-90. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_74E3A21E1736]
 
Immunoreactivity of Sera From Low to Moderate Malaria-Endemic Areas Against Plasmodium vivax rPvs48/45 Proteins Produced in Escherichia coli and Chinese Hamster Ovary Systems.
Arévalo-Herrera M., Miura K., Cespedes N., Echeverry C., Solano E., Castellanos A., Ramirez J.S., Miranda A., Kajava A.V., Long C. et al., 2021. Frontiers in immunology, 12 p. 634738. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C2828818013D]
 
Methods for the Administration of EDAR Pathway Modulators in Mice.
Schuepbach-Mallepell S., Kowalczyk-Quintas C., Dick A., Eslami M., Vigolo M., Headon D.J., Cheeseman M., Schneider H., Schneider P., 2021. pp. 167-183 dans The TNF Superfamily, Springer.
[URN][DOI][WoS][Pmid][serval:BIB_7E7970A5AB18]
Multiparameter Flow Cytometry Analysis of the Human Spleen Applied to Studies of Plasma-Derived EVs From Plasmodium vivax Patients.
Gualdrón-López M., Díaz-Varela M., Toda H., Aparici-Herraiz I., Pedró-Cos L., Lauzurica R., Lacerda MVG, Fernández-Sanmartín M.A., Fernandez-Becerra C., Del Portillo H.A., 2021. Frontiers in cellular and infection microbiology, 11 p. 596104. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1A7C08378975]
Neutrophil Activation: Influence of Antimony Tolerant and Susceptible Clinical Strains of L. (V.) panamensis and Meglumine Antimoniate.
Fernández O.L., Ramírez L.G., Díaz-Varela M., Tacchini-Cottier F., Saravia N.G., 2021. Frontiers in cellular and infection microbiology, 11 p. 710006. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_690EB8B0D8DE]
 
Phenformin Promotes Keratinocyte Differentiation via the Calcineurin/NFAT Pathway.
Zhou Q., Kim S.H., Pérez-Lorenzo R., Liu C., Huang M., Dotto G.P., Zheng B., Wu X., 2021/01. The Journal of investigative dermatology, 141 (1) pp. 152-163. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B79643FFD3B7]
The Impact of Neutrophil Recruitment to the Skin on the Pathology Induced by Leishmania Infection.
Passelli K., Billion O., Tacchini-Cottier F., 2021. Frontiers in immunology, 12 p. 649348. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_64FCD07B80B9]
2020
 
NCoR1 fine‐tunes type‐I IFN response in cDC1 dendritic cells by directly regulating Myd88‐IRF7 axis under TLR9
Ahad Abdul, Smita Shuchi, Mishra Gyan Prakash, Biswas Viplov Kumar, Sen Kaushik, Gupta Bhawna, Garcin Dominique, Acha-Orbea Hans, Raghav Sunil K., 2020/12. European Journal of Immunology, 50 (12) pp. 1959-1975. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CEF35453005F]
Visualizing cellular heterogeneity by quantifying the dynamics of MAPK activity in live mammalian cells with synthetic fluorescent biosensors.
Ma M., Bordignon P., Dotto G.P., Pelet S., 2020/12. Heliyon, 6 (12) pp. e05574. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DD688230BF62]
Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation.
Pais Ferreira D., Silva J.G., Wyss T., Fuertes Marraco S.A., Scarpellino L., Charmoy M., Maas R., Siddiqui I., Tang L., Joyce J.A. et al., 2020/11/17. Immunity, 53 (5) pp. 985-1000.e11. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A0FD9237651F]
Evaluation of a New Topical Treatment for the Control of Cutaneous Leishmaniasis.
Martínez-Salazar B., Carregaro Pereira V., Hauyon-La-Torre Y., Khamesipour A., Tacchini-Cottier F., 2020/11/17. Microorganisms, 8 (11) p. 1803. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4B19C6BD731C]
 
A coumarin embedded highly sensitive nitric oxide fluorescent sensor: kinetic assay and bio-imaging applications.
Maiti D., Islam ASM, Sasmal M., Dutta A., Katarkar A., Ali M., 2020/11/07. Organic & biomolecular chemistry, 18 (41) pp. 8450-8458. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1F0A48641C89]
Caspase-8-dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality.
Demarco B., Grayczyk J.P., Bjanes E., Le Roy D., Tonnus W., Assenmacher C.A., Radaelli E., Fettrelet T., Mack V., Linkermann A. et al., 2020/11. Science advances, 6 (47) pp. eabc3465. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1DC0C3FF12E6]
 
NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin.
Katarkar A., Bottoni G., Clocchiatti A., Goruppi S., Bordignon P., Lazzaroni F., Gregnanin I., Ostano P., Neel V., Dotto G.P., 2020/10/12. Nature communications, 11 (1) p. 5126. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3F36022D1851]
 
Response by the author.
Dotto G.P., 2020/10/05. EMBO reports, 21 (10) pp. e51505. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_759479FB1CC1]
Molecular Diagnostics and In Utero Therapeutics for Orofacial Clefts.
Oliver J.D., Turner E.C., Halpern L.R., Jia S., Schneider P., D'Souza R.N., 2020/10. Journal of dental research, 99 (11) pp. 1221-1227. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_41FCE1137086]
Viruses of protozoan parasites and viral therapy: Is the time now right?
Barrow P., Dujardin J.C., Fasel N., Greenwood A.D., Osterrieder K., Lomonossoff G., Fiori P.L., Atterbury R., Rossi M., Lalle M., 2020/09/29. Virology journal, 17 (1) p. 142. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C4D5A7E05A6B]
Neutralization of B-Cell Activating Factor (BAFF) by Belimumab Reinforces Small Molecule Inhibitor Treatment in Chronic Lymphocytic Leukemia.
Tandler C., Schmidt M., Heitmann J.S., Hierold J., Schmidt J., Schneider P., Dörfel D., Walz J., Salih H.R., 2020/09/23. Cancers, 12 (10) pp. E2725. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_200C5A22FFCC]
 
A Comparison of Intramuscular and Subcutaneous Administration of LigA Subunit Vaccine Adjuvanted with Neutral Liposomal Formulation Containing Monophosphoryl Lipid A and QS21.
Techawiwattanaboon T., Barnier-Quer C., Palaga T., Jacquet A., Collin N., Sangjun N., Komanee P., Patarakul K., 2020/09/01. Vaccines, 8 (3). Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3F117F9152A3]
Cross talk between intracellular pathogens and cell death.
Demarco B., Chen K.W., Broz P., 2020/09. Immunological reviews, 297 (1) pp. 174-193. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_456F4BB4C5ED]
Electrophilic Nrf2 activators and itaconate inhibit inflammation at low dose and promote IL-1β production and inflammatory apoptosis at high dose.
Muri J., Wolleb H., Broz P., Carreira E.M., Kopf M., 2020/09. Redox biology, 36 p. 101647. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_FBF85D95AF9E]
Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells.
Valdivia A., Cárdenas A., Brenet M., Maldonado H., Kong M., Díaz J., Burridge K., Schneider P., San Martín A., García-Mata R. et al., 2020/08/18. Cell communication and signaling, 18 (1) p. 129. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_E77A71624E72]
Role of ETS1 in the Transcriptional Network of Diffuse Large B Cell Lymphoma of the Activated B Cell-Like Type.
Priebe V., Sartori G., Napoli S., Chung EYL, Cascione L., Kwee I., Arribas A.J., Mensah A.A., Rinaldi A., Ponzoni M. et al., 2020/07/15. Cancers, 12 (7). Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_85A502AF6D6C]
To be or not to be: The second law of thermodynamics and the flow of life and death.
Dotto G.P., 2020/07/03. EMBO reports, 21 (7) pp. e50861. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_FA2DAEC7AE2D]
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria.
Santos J.C., Boucher D., Schneider L.K., Demarco B., Dilucca M., Shkarina K., Heilig R., Chen K.W., Lim RYH, Broz P., 2020/06/24. Nature communications, 11 (1) p. 3276. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_241083E0FA4C]
 
TLR7 Sensing by Neutrophils Is Critical for the Control of Cutaneous Leishmaniasis.
Regli I.B., Passelli K., Martínez-Salazar B., Amore J., Hurrell B.P., Müller A.J., Tacchini-Cottier F., 2020/06/09. Cell reports, 31 (10) p. 107746. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2F72D18D6436]
Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD.
Heilig R., Dilucca M., Boucher D., Chen K.W., Hancz D., Demarco B., Shkarina K., Broz P., 2020/06. Life science alliance, 3 (6) pp. e202000735. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0F375D8FC416]
Combined Lung and Liver Transplantation for Short Telomere Syndrome.
Moschouri E., Vionnet J., Giostra E., Daccord C., Lazor R., Sciarra A., Letovanec I., Sempoux C., Gonzalez M., Unger S. et al., 2020/06. Liver transplantation, 26 (6) pp. 840-844. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_67847DD9BC0A]
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell
Eran Mick, Denis V Titov, Owen S Skinner, Rohit Sharma, Alexis A Jourdain, Vamsi K Mootha, 2020/05/28. eLife. Peer-reviewed.
[URN][DOI][serval:BIB_CF8AE559AA6A]
 
Differentially regulated promoters for antigen expression in Salmonella vaccine strains.
Stojanov M., Besançon H., Snäkä T., Nardelli-Haefliger D., Curtiss R., Baud D., 2020/05/27. Vaccine, 38 (26) pp. 4154-4161. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CBE4BD411F79]
The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens.
Rodriguez-Barbosa J.I., Schneider P., Graca L., Bühler L., Perez-Simon J.A., Del Rio M.L., 2020/05/09. International journal of molecular sciences, 21 (9) p. 3347. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BFABD30627E7]
 
Viral Double-Stranded RNA Detection by DNase I and Nuclease S1 digestions in Leishmania parasites.
Isorce N., Fasel N., 2020/05/05. Bio-protocol, 10 (9) pp. e3598. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E819D1295762]
 
M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis.
Lee S.H., Chaves M.M., Kamenyeva O., Gazzinelli-Guimaraes P.H., Kang B., Pessenda G., Passelli K., Tacchini-Cottier F., Kabat J., Jacobsen E.A. et al., 2020/04/10. Science immunology, 5 (46) pp. eaaz4415. Peer-reviewed.
[DOI][Pmid][serval:BIB_493458DC46CB]
SPACE I - 2019 – Council of Europe Annual Penal Statistics: Prison populations
Aebi Marcelo F., Tiago Mélanie M., 2020/04/05., Council of Europe.
[URN][serval:BIB_4540ECD48179]
Out of Africa: The origins of the protozoan blood parasites of the Trypanosoma cruzi clade found in bats from Africa.
Clément L., Dietrich M., Markotter W., Fasel N.J., Monadjem A., López-Baucells A., Scaravelli D., Théou P., Pigeault R., Ruedi M. et al., 2020/04. Molecular phylogenetics and evolution, 145 p. 106705. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D63E4CE1F4DC]
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Canton de Vaud
Swiss University