Department of Biomedical Sciences

Publications | Phd and Masters theses

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2757 publications

 
CDK4 deletion in mice prevents fat accumulation and increases endurance capacity through activation of estrogen-related receptor (ERR)-driven oxidative metabolism in skeletal muscle
Barquissau Valentin, Zanou Nadège, Geller Sarah, Castillo-Armengol Judit, Marzetta Flavia, Huber Katharina, Ziegler Dorian, Lopez-Mejia Isabel, Fernandez Joan Blanco, Roger Catherine et al..
 
Is the “classic model” irrelevant or incomplete for short trail running performance?
Millet G. P., Borrani F., Letter accepted then rejected by MSSE. was published online on social network.
 
RyR1 protein content is reduced in inflammatory and mitochondrial myopathies and induces ER stress
Vidal Jeremy, Fernandez Eric Aria, Wohlwend Martin, Laurila Pirkka-Pekka, Lopez Mejia Andrea, Ochala Julien, Lopez Mejia Isabel, Lobrinus Johannes Alexandre, Kayser Bengt, Place Nicolas et al..
 
Inactivation of hypocretin receptor-2 signaling in dopaminergic neurons induces hyperarousal and enhanced cognition but impaired inhibitory control.
Bandarabadi M., Li S., Aeschlimann L., Colombo G., Tzanoulinou S., Tafti M., Becchetti A., Boutrel B., Vassalli A. Molecular psychiatry. Peer-reviewed.
 
Neuro-immune interactions in health and disease: Insights from FENS-Hertie 2022 Winter School.
Binder L.B., Rosa P.B., de Sousa B.M., Chagas L.S., Dubljević O., Martineau F.S., Mottarlini F., Castany S., Morton L., Krstanović F. et al. The European journal of neuroscience. Peer-reviewed.
 
Elevation of hypothalamic ketone bodies induces a decrease in energy expenditures and an increase risk of metabolic disorder.
Carneiro L., Bernasconi R., Bernini A., Repond C., Pellerin L. Molecular metabolism. Peer-reviewed.
 
Plasticity of neuronal dynamics in the lateral habenula for cue-punishment associative learning.
Congiu M., Mondoloni S., Zouridis I.S., Schmors L., Lecca S., Lalive A.L., Ginggen K., Deng F., Berens P., Paolicelli R.C. et al. Molecular psychiatry. Peer-reviewed.
Comparison of different machine learning models to enhance sacral acceleration-based estimations of running stride temporal variables and peak vertical ground reaction force.
Patoz A., Lussiana T., Breine B., Gindre C., Malatesta D. Sports biomechanics. Peer-reviewed.
Examination of running pattern consistency across speeds.
Patoz A., Lussiana T., Breine B., Gindre C., Malatesta D., Hébert-Losier K. Sports biomechanics. Peer-reviewed.
 
Microglia in Health and Diseases: Integrative Hubs of the Central Nervous System (CNS).
Sierra A., Miron V.E., Paolicelli R.C., Ransohoff R.M. Cold Spring Harbor perspectives in biology. Peer-reviewed.
 
FRET Sensor‐Modified Synthetic Hydrogels for Real‐Time Monitoring of Cell‐Derived Matrix Metalloproteinase Activity using Fluorescence Lifetime Imaging
Yan Ziqian, Kavanagh Thomas, da Silva Harrabi Ricardo, Lust Suzette T., Tang Chunling, Beavil Rebecca L., Müller Manuel M., Beavil Andrew J., Ameer-Beg Simon, da Silva Ricardo M.P. et al. Advanced Functional Materials. Peer-reviewed.
 
Functional hypoxia reduces mitochondrial calcium uptake.
Donnelly C., Komlódi T., Cecatto C., Cardoso LHD, Compagnion A.C., Matera A., Tavernari D., Campiche O., Paolicelli R.C., Zanou N. et al., 2024/05. Redox biology, 71 p. 103037. Peer-reviewed.
ATAC-clock: An aging clock based on chromatin accessibility.
Morandini F., Rechsteiner C., Perez K., Praz V., Lopez Garcia G., Hinte L.C., von Meyenn F., Ocampo A., 2024/04. GeroScience, 46 (2) pp. 1789-1806. Peer-reviewed.
 
The paradox of REM sleep: Seven decades of evolution.
Bandarabadi M., Prouvot Bouvier P.H., Corsi G., Tafti M., 2024/04. Sleep medicine reviews, 74 p. 101918. Peer-reviewed.
 
Closing the scissor-shaped curve: Strategies to promote gender equality in academia.
Joyce J.A., Masina S., Michalik L., Pot C., Sempoux C., Amati F., 2024/03/14. Cell, 187 (6) pp. 1335-1342. Peer-reviewed.
 
Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective.
Lv Z., Chen L., Chen P., Peng H., Rong Y., Hong W., Zhou Q., Li N., Li B., Paolicelli R.C. et al., 2024/03/06. Neuron, 112 (5) pp. 740-754.e7. Peer-reviewed.
AKAP2-anchored extracellular signal-regulated kinase 1 (ERK1) regulates cardiac myofibroblast migration.
Delaunay M., Paterek A., Gautschi I., Scherler G., Diviani D., 2024/03. Biochimica et biophysica acta. Molecular cell research, 1871 (3) p. 119674. Peer-reviewed.
 
Tmprss2 maintains epithelial barrier integrity and transepithelial sodium transport.
Rickman O.J., Guignard E., Chabanon T., Bertoldi G., Auberson M., Hummler E., 2024/03. Life science alliance, 7 (3) pp. e202302304. Peer-reviewed.
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Agius Thomas, Emsley Raffaella, Lyon Arnaud, MacArthur Michael R., Kiesworo Kevin, Faivre Anna, Stavart Louis, Lambelet Martine, Legouis David, de Seigneux Sophie et al., 2024/02/05. Nature Communications, 15 (1).
 
DNA repair-deficient premature aging models display accelerated epigenetic age.
Perez K., Parras A., Picó S., Rechsteiner C., Haghani A., Brooke R., Mrabti C., Schoenfeldt L., Horvath S., Ocampo A., 2024/02. Aging cell, 23 (2) pp. e14058. Peer-reviewed.
Listen to Your Gut: Key Concepts for Bioengineering Advanced Models of the Intestine.
Cameron O., Neves J.F., Gentleman E., 2024/02. Advanced science, 11 (5) pp. e2302165. Peer-reviewed.
Partial cellular reprogramming: A deep dive into an emerging rejuvenation technology.
Paine P.T., Nguyen A., Ocampo A., 2024/02. Aging cell, 23 (2) pp. e14039. Peer-reviewed.
Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments.
Hopf N.B., Suter-Dick L., Huwyler J., Borgatta M., Hegg L., Pamies D., Paschoud H., Puligilla R.D., Reale E., Werner S. et al., 2024/01/18. JMIR research protocols, 13 pp. e50300. Peer-reviewed.
AKAP2-anchored protein phosphatase 1 controls prostatic neuroendocrine carcinoma cell migration and invasion.
Reggi E., Kaiser S., Sahnane N., Uccella S., La Rosa S., Diviani D., 2024/01. Biochimica et biophysica acta. Molecular basis of disease, 1870 (1) p. 166916. Peer-reviewed.
MarrowCellDLD: a microfluidic method for label-free retrieval of fragile bone marrow-derived cells.
Porro G., Sarkis R., Obergozo C., Godot L., Amato F., Humbert M., Naveiras O., Guiducci C., 2023/12/18. Scientific reports, 13 (1) p. 22462. Peer-reviewed.
Hypoxia and the Aging Cardiovascular System.
Raberin A., Burtscher J., Burtscher M., Millet G.P., 2023/12/01. Aging and disease, 14 (6) pp. 2051-2070. Peer-reviewed.
 
In Vivo Cardiac Diffusion Imaging Without Motion-Compensation Leads to Unreasonably High Diffusivity.
Moulin K., Stoeck C.T., Axel L., Broncano J., Croisille P., Dall'Armellina E., Ennis D.B., Ferreira P.F., Gotschy A., Miro S. et al., 2023/12. Journal of magnetic resonance imaging, 58 (6) pp. 1990-1991. Peer-reviewed.
 
In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A., Vílchez-Acosta A., Desdín-Micó G., Picó S., Mrabti C., Montenegro-Borbolla E., Maroun C.Y., Haghani A., Brooke R., Del Carmen Maza M. et al., 2023/12. Nature aging, 3 (12) pp. 1509-1520. Peer-reviewed.
Ryanodine receptor type 1 content decrease-induced endoplasmic reticulum stress is a hallmark of myopathies.
Vidal J., Fernandez E.A., Wohlwend M., Laurila P.P., Lopez-Mejia A., Ochala J., Lobrinus A.J., Kayser B., Lopez-Mejia I.C., Place N. et al., 2023/12. Journal of cachexia, sarcopenia and muscle, 14 (6) pp. 2882-2897. Peer-reviewed.
 
Dietary Potassium Supplementation Reduces Chronic Kidney Lesions Independent of Blood Pressure in Deoxycorticosterone-Acetate and High Sodium Chloride-Treated Mice.
Wang Q., Schäfer S.C., Haefliger J.A., Maillard M.P., Alonso F., 2023/11/28. International journal of molecular sciences, 24 (23) p. 16858. Peer-reviewed.
Urbanization associates with restricted gut microbiome diversity and delayed maturation in infants.
Morandini F., Perez K., Brot L., Seck S.M., Tibère L., Grill J.P., Macia E., Seksik P., 2023/11/17. iScience, 26 (11) p. 108136. Peer-reviewed.
 
The PAD-adapted 30-20-10: a new high intensity exercise session in patients with symptomatic chronic peripheral artery disease
Mazzolai Lucia (eds.), 2023/11/16., Congrès de l’Union des Sociétés Suisses des Maladies Vasculaires. Lausanne..
 
Heterogeneity of TPIT expression in ACTH-secreting extra-pituitary neuroendocrine tumors (NETs) supports the existence of different cellular programs in pancreatic and pulmonary NETs.
Uccella S., Leoni E., Kaiser S., Maragliano R., Valerio A., Libera L., Tanda M.L., Volante M., Diviani D., La Rosa S., 2023/11. Virchows Archiv, 483 (5) pp. 635-643. Peer-reviewed.
 
Renal tubular SGK1 is required to achieve blood pressure surge and circadian rhythm.
Staub O., Debonneville A., Stifanelli M., Juffre A., Maillard M.P., Gumz M.L., Al-Qusairi L., 2023/11/01. American journal of physiology. Renal physiology, 325 (5) pp. F629-F637. Peer-reviewed.
 
Vitamin B12 emerges as key player during cellular reprogramming.
Vílchez-Acosta A., Desdín-Micó G., Ocampo A., 2023/11. Nature metabolism, 5 (11) pp. 1844-1845. Peer-reviewed.
 
Metabolic regulation of microglial phagocytosis: Implications for Alzheimer's disease therapeutics.
Lepiarz-Raba I., Gbadamosi I., Florea R., Paolicelli R.C., Jawaid A., 2023/10/31. Translational neurodegeneration, 12 (1) p. 48. Peer-reviewed.
Moderate Effects of Hypoxic Training at Low and Supramaximal Intensities on Skeletal Muscle Metabolic Gene Expression in Mice.
Drozdovska S., Zanou N., Lavier J., Mazzolai L., Millet G.P., Pellegrin M., 2023/10/21. Metabolites, 13 (10) p. 1103. Peer-reviewed.
 
Exercising at high intensity in patients with chronic symptomatic peripheral artery disease: the new PAD-adapted 30-20-10 session
Heiss Christian (eds.), 2023/10/12., 9th Congress of the European Society for Vascular Medicine. Milan, Italy..
 
Celebrating 100 years of VO2max.
Burtscher J., Millet G.P., Burtscher M., 2023/10/06. QJM, 116 (9) p. 809. Peer-reviewed.
 
Comparison of western diet-induced obesity and streptozotocin mouse models: insights into energy balance, somatosensory dysfunction, and cardiac autonomic neuropathy.
Elshareif N., Gornick E., Gavini C.K., Aubert G., Mansuy-Aubert V., 2023/10. Frontiers in physiology, 14 p. 1238120. Peer-reviewed.
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
Alexander SPH, Mathie A.A., Peters J.A., Veale E.L., Striessnig J., Kelly E., Armstrong J.F., Faccenda E., Harding S.D., Davies J.A. et al., 2023/10. British journal of pharmacology, 180 (Suppl 2) pp. S145-S222. Peer-reviewed.
Kidney-Specific Membrane-Bound Serine Proteases CAP1/Prss8 and CAP3/St14 Affect ENaC Subunit Abundances but Not Its Activity.
Ehret E., Stroh S., Auberson M., Ino F., Jäger Y., Maillard M., Szabo R., Bugge T.H., Frateschi S., Hummler E., 2023/09/23. Cells, 12 (19). Peer-reviewed.
Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice.
Monsorno K., Ginggen K., Ivanov A., Buckinx A., Lalive A.L., Tchenio A., Benson S., Vendrell M., D'Alessandro A., Beule D. et al., 2023/09/16. Nature communications, 14 (1) p. 5749. Peer-reviewed.
Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems.
Girotra M., Chiang Y.H., Charmoy M., Ginefra P., Hope H.C., Bataclan C., Yu Y.R., Schyrr F., Franco F., Geiger H. et al., 2023/09. Nature aging, 3 (9) pp. 1057-1066. Peer-reviewed.
Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activity.
Bartos K., Ramakrishnan S.K., Braga-Lagache S., Hänzi B., Durussel F., Prakash Sridharan A., Zhu Y., Sheehan D., Hynes N.E., Bonny O. et al., 2023/09. Journal of cell communication and signaling, 17 (3) pp. 705-722. Peer-reviewed.
 
Overexpression of miR-297b-5p in Mouse Insulin-Secreting Cells Promotes Metformin-Mediated Protection Against Stearic Acid-Induced Senescence by Targeting Igf1r.
Zhao Q., Su S., Lin Y., Li X., Dan L., Yang C., Geng C., Regazzi R., Li X., Dong Y. et al., 2023/08/28. Frontiers in bioscience, 28 (8) p. 181. Peer-reviewed.
ASIC1a affects hypothalamic signaling and regulates the daily rhythm of body temperature in mice.
Peng Z., Ziros P.G., Martini T., Liao X.H., Stoop R., Refetoff S., Albrecht U., Sykiotis G.P., Kellenberger S., 2023/08/17. Communications biology, 6 (1) p. 857. Peer-reviewed.
Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
Kallergi E., Siva Sankar D., Matera A., Kolaxi A., Paolicelli R.C., Dengjel J., Nikoletopoulou V., 2023/08/02. Neuron, 111 (15) pp. 2329-2347.e7. Peer-reviewed.
 
Simultaneous Quantification of 16 Bisphenol Analogues in Food Matrices.
Lucarini F., Gasco R., Staedler D., 2023/08/02. Toxics, 11 (8) p. 665. Peer-reviewed.
 
Creating awareness about exercise-based ACL prevention strategies in recreational alpine skiers.
Burtscher M., Kopp M., Millet G.P., Burtscher J., Ruedl G., 2023/08. British journal of sports medicine, 57 (15) pp. 955-956. Peer-reviewed.
 
Neural stem cell metabolism revisited: a critical role for mitochondria.
Scandella V., Petrelli F., Moore D.L., Braun SMG, Knobloch M., 2023/08. Trends in endocrinology and metabolism, 34 (8) pp. 446-461. Peer-reviewed.
 
A mild and transient form of autosomal recessive pseudohypoaldosteronism type 1 caused by a novel mutation in the SCNN1A gene.
Efthymiadou A., Gautschi I., van Bemmelen M.X., Sertedaki A., Giannakopoulos A., Chrousos G., Schild L., Chrysis D., 2023/07/01. American journal of physiology. Endocrinology and metabolism, 325 (1) pp. E1-E9. Peer-reviewed.
Differences in the Food Consumption Between Kidney Stone Formers and Nonformers in the Swiss Kidney Stone Cohort.
Legay C., Haeusermann T., Pasquier J., Chatelan A., Fuster D.G., Dhayat N., Seeger H., Ritter A., Mohebbi N., Ernandez T. et al., 2023/07. Journal of renal nutrition, 33 (4) pp. 555-565. Peer-reviewed.
G × E interactions as a basis for toxicological uncertainty.
Suciu I., Pamies D., Peruzzo R., Wirtz P.H., Smirnova L., Pallocca G., Hauck C., Cronin MTD, Hengstler J.G., Brunner T. et al., 2023/07. Archives of toxicology, 97 (7) pp. 2035-2049. Peer-reviewed.
 
Human brain microphysiological systems in the study of neuroinfectious disorders.
Barreras P., Pamies D., Hartung T., Pardo C.A., 2023/07. Experimental neurology, 365 p. 114409. Peer-reviewed.
Impact of Preoperative Psychiatric Profile in Bariatric Surgery on Long-term Weight Outcome.
Lüscher A., Vionnet N., Amiguet M., Chartoumpekis D., Mantziari S., Frantz J., Favre L., 2023/07. Obesity surgery, 33 (7) pp. 2072-2082. Peer-reviewed.
Multimodal assessment of non-alcoholic fatty liver disease with transmission-reflection optoacoustic ultrasound.
Lafci B., Hadjihambi A., Determann M., Konstantinou C., Freijo C., Herraiz J.L., Blümel S., Pellerin L., Burton N.C., Deán-Ben X.L. et al., 2023/07. Theranostics, 13 (12) pp. 4217-4228. Peer-reviewed.
Short chain fatty acids: the messengers from down below.
Mansuy-Aubert V., Ravussin Y., 2023/07. Frontiers in neuroscience, 17 p. 1197759. Peer-reviewed.
The P2X7 receptor contributes to seizures and inflammation-driven long-lasting brain hyperexcitability following hypoxia in neonatal mice.
Smith J., Menéndez Méndez A., Alves M., Parras A., Conte G., Bhattacharya A., Ceusters M., Nicke A., Henshall D.C., Jimenez-Mateos E.M. et al., 2023/07. British journal of pharmacology, 180 (13) pp. 1710-1729. Peer-reviewed.
Vertical and Leg Stiffness Modeling During Running: Effect of Speed and Incline.
Meyer F., Falbriard M., Aminian K., Millet G.P., 2023/07. International journal of sports medicine, 44 (9) pp. 673-679. Peer-reviewed.
Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis.
Fries A., Saidoune F., Kuonen F., Dupanloup I., Fournier N., Guerra de Souza A.C., Haniffa M., Ma F., Gudjonsson J.E., Roesner L. et al., 2023/06/30. Nature communications, 14 (1) p. 3878. Peer-reviewed.
An information theoretic approach to detecting spatially varying genes.
Jones D.C., Danaher P., Kim Y., Beechem J.M., Gottardo R., Newell E.W., 2023/06/26. Cell reports methods, 3 (6) p. 100507. Peer-reviewed.
Flying to high-altitude destinations: Is the risk of acute mountain sickness greater?
Burtscher J., Swenson E.R., Hackett P.H., Millet G.P., Burtscher M., 2023/06/23. Journal of travel medicine, 30 (4). Peer-reviewed.
 
Left ventricular function and mechanics in backs and forwards elite rugby union players.
Fornasier-Santos C., Izem O., Aboukhoudir F., Rupp T., Stridgeon P., Millet G.P., Nottin S., 2023/06. European journal of sport science, 23 (6) pp. 904-913. Peer-reviewed.
 
Re: "Barometric Pressure at High Altitude: Revisiting West's Prediction Equation, and More," by Apte.
Debevec T., Millet G.P., 2023/06. High altitude medicine & biology, 24 (2) pp. 153-154. Peer-reviewed.
 
Reduced mortality in cooler surroundings.
Burtscher J., Millet G.P., Burtscher M., 2023/05/27. Lancet, 401 (10390) p. 1771. Peer-reviewed.
Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy.
Seifinejad A., Ramosaj M., Shan L., Li S., Possovre M.L., Pfister C., Fronczek R., Garrett-Sinha L.A., Frieser D., Honda M. et al., 2023/05/09. Proceedings of the National Academy of Sciences of the United States of America, 120 (19) pp. e2220911120. Peer-reviewed.
How much resistance exercise is beneficial for healthy aging and longevity?
Burtscher J., Strasser B., D'Antona G., Millet G.P., Burtscher M., 2023/05. Journal of sport and health science, 12 (3) pp. 284-286. Peer-reviewed.
 
Multi-hosting UEFA European Football Championship: fair enough between participating teams?
Brocherie F., De Larochelambert Q., Millet G.P., 2023/05. Science & medicine in football, 7 (2) pp. 171-176. Peer-reviewed.
Tanycyte, the neuron whisperer.
Dali R., Estrada-Meza J., Langlet F., 2023/05/01. Physiology & behavior, 263 p. 114108. Peer-reviewed.
Microvascular and oxidative stress responses to acute high-altitude exposure in prematurely born adults.
Manferdelli G., Narang B.J., Pialoux V., Giardini G., Debevec T., Millet G.P., 2023/04/26. Scientific reports, 13 (1) p. 6860. Peer-reviewed.
Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock.
Bignon Y., Wigger L., Ansermet C., Weger B.D., Lagarrigue S., Centeno G., Durussel F., Götz L., Ibberson M., Pradervand S. et al., 2023/04/17. The Journal of clinical investigation, 133 (8) pp. e167133. Peer-reviewed.
Physical Performance and Skeletal Muscle Transcriptional Adaptations Are Not Impacted by Exercise Training Frequency in Mice with Lower Extremity Peripheral Artery Disease.
Lavier J., Bouzourène K., Millet G.P., Mazzolai L., Pellegrin M., 2023/04/16. Metabolites, 13 (4) p. 562. Peer-reviewed.
 
The phytase RipBL1 enables the assignment of a specific inositol phosphate isomer as a structural component of human kidney stones.
Liu G., Riemer E., Schneider R., Cabuzu D., Bonny O., Wagner C.A., Qiu D., Saiardi A., Strauss A., Lahaye T. et al., 2023/04/05. RSC chemical biology, 4 (4) pp. 300-309. Peer-reviewed.
 
Current Status and Challenges of Vaccination Therapy for Glioblastoma.
Hosseinalizadeh H., Rahmati M., Ebrahimi A., O'Connor R.S., 2023/04/03. Molecular cancer therapeutics, 22 (4) pp. 435-446. Peer-reviewed.
 
Effects of repeated-sprint training in hypoxia induced by voluntary hypoventilation on performance during ice hockey off-season
Brocherie Franck, Cantamessi Gregory, Millet Grégoire P., Woorons Xavier, 2023/04. International Journal of Sports Science & Coaching, 18 (2) pp. 446-452. Peer-reviewed.
 
Sphingolipids and impaired hypoxic stress responses in Huntington disease.
Burtscher J., Pepe G., Maharjan N., Riguet N., Di Pardo A., Maglione V., Millet G.P., 2023/04. Progress in lipid research, 90 p. 101224. Peer-reviewed.
Both Hypoxia and Hypobaria Impair Baroreflex Sensitivity but through Different Mechanisms.
Bourdillon N., Aebi M.R., Kayser B., Bron D., Millet G.P., 2023/03. International journal of sports medicine, 44 (3) pp. 177-183. Peer-reviewed.
 
End-tidal carbon dioxide tension is a reliable surrogate of arterial carbon dioxide tension across different oxygen, carbon dioxide and barometric pressures.
Manferdelli G., Narang B.J., Bourdillon N., Debevec T., Millet G.P., 2023/03. ERJ open research, 9 (2) pp. 00507-2022. Peer-reviewed.
 
Endovascular Repair of an Ascending Aortic Pseudoaneurysm.
Longchamp A., Déglise S., 2023/03. European journal of vascular and endovascular surgery, 65 (3) p. 423. Peer-reviewed.
 
High-Intensity Interval Training, Performance, and Oxygen Uptake Kinetics in Highly Trained Traditional Rowers.
Mujika I., Bourdillon N., González De Txabarri R., Millet G.P., 2023/03/01. International journal of sports physiology and performance, 18 (3) pp. 326-330. Peer-reviewed.
Intrahospital supervised exercise training improves survival rate among hypertensive patients with COVID-19.
Fernandez F., Vazquez-Muñoz M., Canals A., Arce-Álvarez A., Salazar-Ardiles C., Alvarez C., Ramirez-Campillo R., Millet G.P., Izquierdo M., Andrade D.C., 2023/03/01. Journal of applied physiology, 134 (3) pp. 678-684. Peer-reviewed.
Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells.
Petrelli F., Scandella V., Montessuit S., Zamboni N., Martinou J.C., Knobloch M., 2023/03. Science advances, 9 (9) pp. eadd5220. Peer-reviewed.
 
Physiological Responses to Exercise in Hypoxia in Preterm Adults: Convective and Diffusive Limitations in the O 2 Transport.
Manferdelli G., Narang B.J., Bourdillon N., Debevec T., Millet G.P., 2023/03/01. Medicine and science in sports and exercise, 55 (3) pp. 482-496. Peer-reviewed.
Plasma membrane depolarization reveals endosomal escape incapacity of cell-penetrating peptides.
Serulla M., Anees P., Hallaj A., Trofimenko E., Kalia T., Krishnan Y., Widmann C., 2023/03. European journal of pharmaceutics and biopharmaceutics, 184 pp. 116-124. Peer-reviewed.
 
VO2max and Velocity at VO2max Play a Role in Ultradistance Trail-Running Performance.
Sabater-Pastor F., Tomazin K., Millet G.P., Verney J., Féasson L., Millet G.Y., 2023/03/01. International journal of sports physiology and performance, 18 (3) pp. 300-305. Peer-reviewed.
A Database of Accurate Electrophoretic Migration Patterns for Human Proteins.
Mylonas R., Potts A., Waridel P., Barblan J., Conde Rubio MDC, Widmann C., Quadroni M., 2023/02/28. Journal of molecular biology, 435 (4) p. 167933. Peer-reviewed.
Accurate estimation of peak vertical ground reaction force using the duty factor in level treadmill running.
Patoz A., Lussiana T., Breine B., Gindre C., Malatesta D., 2023/02. Scandinavian journal of medicine & science in sports, 33 (2) pp. 169-177. Peer-reviewed.
 
Converting Steps Into Physical Activity Time.
Burtscher J., Millet G.P., Burtscher M., 2023/02/01. JAMA internal medicine, 183 (2) p. 170. Peer-reviewed.
Fecal microbiome transplantation and tributyrin improves early cardiac dysfunction and modifies the BCAA metabolic pathway in a diet induced pre-HFpEF mouse model.
Hatahet J., Cook T.M., Bonomo R.R., Elshareif N., Gavini C.K., White C.R., Jesse J., Mansuy-Aubert V., Aubert G., 2023/02. Frontiers in cardiovascular medicine, 10 p. 1105581. Peer-reviewed.
 
Hypoxia Does Not Change Performance and Psychophysiological Responses During Repeated Cycling Sprints to Exhaustion With Short Exercise-to-Rest Ratio.
Raberin A., Willis S.J., Richard T., Elmer J., Vernillo G., Iaia F.M., Girard O., Malatesta D., Millet G.P., 2023/02/01. International journal of sports physiology and performance, 18 (2) pp. 213-217. Peer-reviewed.
Methodological advancements in organ-specific ectopic lipid quantitative characterization: Effects of high fat diet on muscle and liver intracellular lipids.
Grepper D., Tabasso C., Aguettaz AKF, Martinotti A., Ebrahimi A., Lagarrigue S., Amati F., 2023/02. Molecular metabolism, 68 p. 101669. Peer-reviewed.
 
Mitochondrial stress and mitokines in aging.
Burtscher J., Soltany A., Visavadiya N.P., Burtscher M., Millet G.P., Khoramipour K., Khamoui A.V., 2023/02. Aging cell, 22 (2) pp. e13770. Peer-reviewed.
 
The Oxidative-Glycolytic Balance Influenced by Sprint Duration Is Key during Repeated Sprint in Hypoxia.
Raberin A., Elmer J., Willis S.J., Richard T., Vernillo G., Iaia F.M., Girard O., Malatesta D., Millet G.P., 2023/02/01. Medicine and science in sports and exercise, 55 (2) pp. 245-254. Peer-reviewed.
 
Ocular Symptoms Associated with COVID-19 Are Correlated with the Expression Profile of Mouse SARS-CoV-2 Binding Sites.
Brechbühl J., Ferreira F., Lopes A.C., Corset E., Gilliand N., Broillet M.C., 2023/01/26. Viruses, 15 (2) p. 354. Peer-reviewed.
Molecular Mechanisms of High-Altitude Acclimatization.
Mallet R.T., Burtscher J., Pialoux V., Pasha Q., Ahmad Y., Millet G.P., Burtscher M., 2023/01/15. International journal of molecular sciences, 24 (2) p. 1698. Peer-reviewed.
Comparative Assessment of the Binding and Neutralisation Activity of Bispecific Antibodies Against SARS-CoV-2 Variants.
Dean A.Q., Stauft C.B., Twomey J.D., Tan J., Varani L., Wang T.T., Zhang B., 2023/01. Antibody therapeutics, 6 (1) pp. 49-58. Peer-reviewed.
Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization.
Kiesworo K., MacArthur M.R., Kip P., Agius T., Macabrey D., Lambelet M., Hamard L., Ozaki C.K., Mitchell J.R., Déglise S. et al., 2023. JVS-vascular science, 4 p. 100095. Peer-reviewed.
Digoxin Induces Human Astrocyte Reaction In Vitro.
Pamies D., Vujić T., Schvartz D., Boccard J., Repond C., Nunes C., Rudaz S., Sanchez J.C., González-Ruiz V., Zurich M.G., 2023/01. Molecular neurobiology, 60 (1) pp. 84-97. Peer-reviewed.
Editorial: Glial heterogeneity: impact on neuronal function and dysfunction.
Bezzi P., Magnaghi V., Paolicelli R.C., Hornung J.P., 2023. Frontiers in neuroanatomy, 17 p. 1249919. Peer-reviewed.
Editorial: Translational behavioral approaches in animal models of psychiatry.
Tzanoulinou S., Passecker J., Stamatakis A., Diamantopoulou A., 2023. Frontiers in behavioral neuroscience, 17 p. 1200691. Peer-reviewed.
 
Glioblastoma as a Novel Drug Repositioning Target: Updated State.
Hosseinalizadeh H., Ebrahimi A., Tavakoli A., Monavari S.H., 2023. Anti-cancer agents in medicinal chemistry, 23 (11) pp. 1253-1264. Peer-reviewed.
 
Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.
Paine P.T., Rechsteiner C., Morandini F., Desdín-Micó G., Mrabti C., Parras A., Haghani A., Brooke R., Horvath S., Seluanov A. et al., 2023. Frontiers in aging, 4 p. 1323194. Peer-reviewed.
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone.
Nunes C., Proença S., Ambrosini G., Pamies D., Thomas A., Kramer N.I., Zurich M.G., 2023. Frontiers in pharmacology, 14 p. 1248882. Peer-reviewed.
 
Isolating the speed factor is crucial in gait analysis for Parkinson's disease.
Patoz A., Malatesta D., Burtscher J., 2023. Frontiers in neuroscience, 17 p. 1119390. Peer-reviewed.
Natural and synthetic nanovectors for cancer therapy.
Eftekhari A., Kryschi C., Pamies D., Gulec S., Ahmadian E., Janas D., Davaran S., Khalilov R., 2023. Nanotheranostics, 7 (3) pp. 236-257. Peer-reviewed.
Partial MCT1 invalidation protects against diet-induced non-alcoholic fatty liver disease and the associated brain dysfunction.
Hadjihambi A., Konstantinou C., Klohs J., Monsorno K., Le Guennec A., Donnelly C., Cox I.J., Kusumbe A., Hosford P.S., Soffientini U. et al., 2023/01. Journal of hepatology, 78 (1) pp. 180-190. Peer-reviewed.
 
Pushing the Limits of Strength Training.
Burtscher J., Millet G.P., Burtscher M., 2023/01. American journal of preventive medicine, 64 (1) pp. 145-146. Peer-reviewed.
Phage therapy for pulmonary infections: lessons from clinical experiences and key considerations.
Mitropoulou G., Koutsokera A., Csajka C., Blanchon S., Sauty A., Brunet J.F., von Garnier C., Resch G., Guery B., 2022/12/31. European respiratory review, 31 (166) p. 220121. Peer-reviewed.
Tumor-Microenvironment Characterization of the MB49 Non-Muscle-Invasive Bladder-Cancer Orthotopic Model towards New Therapeutic Strategies.
Domingos-Pereira S., Sathiyanadan K., Polak L., Haefliger J.A., Schmittnaegel M., Ries C.H., Jichlinski P., Roth B., Derré L., Nardelli-Haefliger D., 2022/12/21. International journal of molecular sciences, 24 (1) p. 123. Peer-reviewed.
Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors.
Markov N.T., Lindbergh C.A., Staffaroni A.M., Perez K., Stevens M., Nguyen K., Murad N.F., Fonseca C., Campisi J., Kramer J. et al., 2022/12/06. Proceedings of the National Academy of Sciences of the United States of America, 119 (49) pp. e2207181119. Peer-reviewed.
 
Acute performance and physiological responses to upper-limb multi-set exercise to failure: Effects of external resistance and systemic hypoxia.
Girard O., Mariotti-Nesurini L., Malatesta D., 2022/12. European journal of sport science, 22 (12) pp. 1877-1888. Peer-reviewed.
Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site
Roy Sophie, Johner Niklaus, Trendafilov Viktor, Gautschi Ivan, Bignucolo Olivier, Molton Ophélie, Bernèche Simon, Kellenberger Stephan, 2022/12. Open Biology, 12 (12) p. 220243. Peer-reviewed.
 
Could Repeated Cardio-Renal Injury Trigger Late Cardiovascular Sequelae in Extreme Endurance Athletes?
Burtscher J., Vanderriele P.E., Legrand M., Predel H.G., Niebauer J., O'Keefe J.H., Millet G.P., Burtscher M., 2022/12. Sports medicine, 52 (12) pp. 2821-2836. Peer-reviewed.
 
Does Altitude of Birth Influence the Performance of National- to Elite-Level Colombian Cyclists?
Garzon M., Leguizamo J., Saldarriaga F., Galeano E., Millet G.P., 2022/12/01. International journal of sports physiology and performance, 17 (12) pp. 1756-1759. Peer-reviewed.
 
Health Benefits of Residence at Moderate Altitude Do Not Reduce COVID-19 Mortality.
Burtscher J., Millet G.P., Leitner B., Burtscher M., 2022/12/01. International journal of environmental research and public health, 19 (23) p. 16074. Peer-reviewed.
Inhibition of miR-146a-5p and miR-8114 in Insulin-Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa.
Su S., Zhao Q., Dan L., Lin Y., Li X., Zhang Y., Yang C., Dong Y., Li X., Regazzi R. et al., 2022/12. Endocrinology and metabolism, 37 (6) pp. 901-917. Peer-reviewed.
 
Muscle O<sub>2</sub> diffusion capacity by NIRS: A new approach in the air.
Manferdelli G., Raberin A., Millet G.P., 2022/12. The Journal of physiology, 600 (23) pp. 5163-5164. Peer-reviewed.
Saxagliptin: A potential doping agent? A randomized, double-blinded, placebo-controlled, and crossover pilot study in young active men.
Bourdillon N., Eugster P.J., Vocat C., Nguyen T., Wuerzner G., Grouzmann E., Millet G.P., 2022/12. Physiological reports, 10 (23) pp. e15515. Peer-reviewed.
 
Sex differences in human running performance: what about mountain ultramarathon?
Millet G.P., Malatesta D., 2022/12/01. Journal of applied physiology, 133 (6) pp. 1300-1301. Peer-reviewed.
 
Wnt signalling in cell division: from mechanisms to tissue engineering.
Habib S.J., Acebrón S.P., 2022/12. Trends in cell biology, 32 (12) pp. 1035-1048. Peer-reviewed.
 
Microglia states and nomenclature: A field at its crossroads.
Paolicelli R.C., Sierra A., Stevens B., Tremblay M.E., Aguzzi A., Ajami B., Amit I., Audinat E., Bechmann I., Bennett M. et al., 2022/11/02. Neuron, 110 (21) pp. 3458-3483. Peer-reviewed.
 
Adaptive Responses to Hypoxia and/or Hyperoxia in Humans.
Burtscher J., Mallet R.T., Pialoux V., Millet G.P., Burtscher M., 2022/11. Antioxidants & redox signaling, 37 (13-15) pp. 887-912. Peer-reviewed.
 
Correction to: Training During the COVID-19 Lockdown: Knowledge, Beliefs, and Practices of 12,526 Athletes from 142 Countries and Six Continents
Washif Jad Adrian, Farooq Abdulaziz, Krug Isabel, Pyne David B., Verhagen Evert, Taylor Lee, Wong Del P., Mujika Iñigo, Cortis Cristina, Haddad Monoem et al., 2022/10/22..
GLUT2 expression by glial fibrillary acidic protein-positive tanycytes is required for promoting feeding-response to fasting.
Barahona M.J., Langlet F., Labouèbe G., Croizier S., Picard A., Thorens B., García-Robles M.A., 2022/10/21. Scientific reports, 12 (1) p. 17717. Peer-reviewed.
 
Analyses of circRNA Expression throughout the Light-Dark Cycle Reveal a Strong Regulation of Cdr1as, Associated with Light Entrainment in the SCN
Ivanov Andranik, Mattei Daniele, Radscheit Kathrin, Compagnion Anne-Claire, Pett Jan Patrick, Herzel Hanspeter, Paolicelli Rosa Chiara, Piwecka Monika, Meyer Urs, Beule Dieter, 2022/10/15. International Journal of Molecular Sciences, 23 (20) p. 12347.
 
Comment on Gattoni et al: Sleep Deprivation Training as a Highway to Hell in Ultratrail.
Millet G.P., Hermand E., Hurdiel R., 2022/10/01. International journal of sports physiology and performance, 17 (10) p. 1455. Peer-reviewed.
 
Last Word on Viewpoint: Premature birth: a neglected consideration for altitude adaptation.
Debevec T., Narang B.J., Manferdelli G., Millet G.P., 2022/10/01. Journal of applied physiology, 133 (4) pp. 983-984. Peer-reviewed.
 
Premature birth: a neglected consideration for altitude adaptation.
Debevec T., Narang B.J., Manferdelli G., Millet G.P., 2022/10/01. Journal of applied physiology, 133 (4) pp. 975-978. Peer-reviewed.
Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel.
Zachar R., Thiel S., Hansen S., Henriksen M.L., Skjoedt M.O., Skjodt K., Hamzaei Z., Madsen K., Lund L., Hummler E. et al., 2022/09/24. Scientific reports, 12 (1) p. 15955. Peer-reviewed.
Impaired fatty acid metabolism perpetuates lipotoxicity along the transition to chronic kidney injury.
Rinaldi A., Lazareth H., Poindessous V., Nemazanyy I., Sampaio J.L., Malpetti D., Bignon Y., Naesens M., Rabant M., Anglicheau D. et al., 2022/09/22. JCI insight, 7 (18) pp. e161783. Peer-reviewed.
Mortality in Recreational Mountain-Biking in the Austrian Alps: A Retrospective Study over 16 Years.
Pocecco E., Wafa H., Burtscher J., Paal P., Plattner P., Posch M., Ruedl G., 2022/09/22. International journal of environmental research and public health, 19 (19) p. 11965. Peer-reviewed.
Galvani Offset Potential and Constant-pH Simulations of Membrane Proteins.
Bignucolo O., Chipot C., Kellenberger S., Roux B., 2022/09/15. The journal of physical chemistry. B, 126 (36) pp. 6868-6877. Peer-reviewed.
Relations entre la médecine et le colonialisme : le parfait exemple de la qunine.
Maggetti N., Staedler D., 2022/09/07. Revue medicale suisse, 18 (794) p. 1681. Peer-reviewed.
 
The Impact of Training on the Loss of Cardiorespiratory Fitness in Aging Masters Endurance Athletes.
Burtscher J., Strasser B., Burtscher M., Millet G.P., 2022/09/03. International journal of environmental research and public health, 19 (17) p. 11050. Peer-reviewed.
Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury.
Prag H.A., Aksentijevic D., Dannhorn A., Giles A.V., Mulvey J.F., Sauchanka O., Du L., Bates G., Reinhold J., Kula-Alwar D. et al., 2022/09/02. Circulation research, 131 (6) pp. 528-541. Peer-reviewed.
A Celebration of the Extraordinary Life of Late Professor Tatiana V. Serebrovskaya (Kyiv, Ukraine) in Advancing Hypoxia Science and Medicine.
Swenson E.R., Mallet R.T., Xi L., Manukhina E., Downey F., Burtscher J., Ehrenreich H., Burtscher M., 2022/09. High altitude medicine & biology, 23 (3) pp. 284-285. Peer-reviewed.
Emerging evidence for astrocyte dysfunction in schizophrenia.
de Oliveira Figueiredo E.C., Calì C., Petrelli F., Bezzi P., 2022/09. Glia, 70 (9) pp. 1585-1604. Peer-reviewed.
Lessons learned about epithelial sodium channels from transgenic mouse models.
Ehret E., Hummler E., 2022/09/01. Current opinion in nephrology and hypertension, 31 (5) pp. 493-501. Peer-reviewed.
 
Quality criteria for in vitro human pluripotent stem cell-derived models of tissue-based cells.
Pistollato F., Bal-Price A., Coecke S., Parvatam S., Pamies D., Czysz K., Hao J., Kee K., Teo AKK, Niu S. et al., 2022/09. Reproductive toxicology, 112 pp. 36-50. Peer-reviewed.
 
Respiratory responses to hypoxia during rest and exercise in individuals born pre-term: a state-of-the-art review.
Narang B.J., Manferdelli G., Millet G.P., Debevec T., 2022/09. European journal of applied physiology, 122 (9) pp. 1991-2003. Peer-reviewed.
Species recognition limits mating between hybridizing ant species.
Blacher P., Zahnd S., Purcell J., Avril A., Honorato T.O., Bailat-Rosset G., Staedler D., Brelsford A., Chapuisat M., 2022/09. Evolution; international journal of organic evolution, 76 (9) pp. 2105-2115. Peer-reviewed.
 
The athletic characteristics of Olympic sports to assist anti-doping strategies.
Hayward G., Gaborini L., Sims D., Schumacher Y.O., Millet G.P., Rhumorbarbe D., Coquet R., Robinson N., 2022/09. Drug testing and analysis, 14 (9) pp. 1599-1613. Peer-reviewed.
 
Wales Anaerobic Test: Reliability and Fitness Profiles of International Rugby Union Players.
Beard A., Ashby J., Chambers R., Millet G.P., Brocherie F., 2022/09/01. Journal of strength and conditioning research, 36 (9) pp. 2589-2596. Peer-reviewed.
Stress-Induced Premature Senescence Related to Oxidative Stress in the Developmental Programming of Nonalcoholic Fatty Liver Disease in a Rat Model of Intrauterine Growth Restriction.
Keshavjee B., Lambelet V., Coppola H., Viertl D., Prior J.O., Kappeler L., Armengaud J.B., Chouraqui J.P., Chehade H., Vanderriele P.E. et al., 2022/08/29. Antioxidants, 11 (9) p. 1695. Peer-reviewed.
 
Can melatonin be used as a potential antioxidant and sleep aid supplement for high-altitude travelers?
Burtscher J., Strasser B., Millet G.P., Burtscher M., 2022/08/20. Journal of travel medicine, 29 (5) pp. taab198. Peer-reviewed.
 
Sex-specific differences in blood pressure responses following acute high-altitude exposure.
Burtscher M., Philadelphy M., Burtscher J., Likar R., 2022/08/20. Journal of travel medicine, 29 (5) pp. taab035. Peer-reviewed.
Photoresponsive Nanocarriers Based on Lithium Niobate Nanoparticles for Harmonic Imaging and On-Demand Release of Anticancer Chemotherapeutics.
Gheata A., Gaulier G., Campargue G., Vuilleumier J., Kaiser S., Gautschi I., Riporto F., Beauquis S., Staedler D., Diviani D. et al., 2022/08/17. ACS nanoscience Au, 2 (4) pp. 355-366. Peer-reviewed.
 
Multiomics assessment of dietary protein titration reveals altered hepatic glucose utilization.
MacArthur M.R., Mitchell S.J., Chadaideh K.S., Treviño-Villarreal J.H., Jung J., Kalafut K.C., Reynolds J.S., Mann C.G., Trocha K.M., Tao M. et al., 2022/08/16. Cell reports, 40 (7) p. 111187. Peer-reviewed.
Abnormal brain oxygen homeostasis in an animal model of liver disease.
Hadjihambi A., Cudalbu C., Pierzchala K., Simicic D., Donnelly C., Konstantinou C., Davies N., Habtesion A., Gourine A.V., Jalan R. et al., 2022/08. JHEP reports, 4 (8) p. 100509. Peer-reviewed.
 
Boosting mitochondrial health to counteract neurodegeneration.
Burtscher J., Romani M., Bernardo G., Popa T., Ziviani E., Hummel F.C., Sorrentino V., Millet G.P., 2022/08. Progress in neurobiology, 215 p. 102289. Peer-reviewed.
 
COVID-19 Lockdown: A Global Study Investigating the Effect of Athletes' Sport Classification and Sex on Training Practices.
Washif J.A., Sandbakk Ø., Seiler S., Haugen T., Farooq A., Quarrie K., Janse van Rensburg D.C., Krug I., Verhagen E., Wong D.P. et al., 2022/08/01. International journal of sports physiology and performance, 17 (8) pp. 1242-1256. Peer-reviewed.
 
Hypoxia and hemorheological properties in older individuals.
Raberin A., Burtscher J., Connes P., Millet G.P., 2022/08. Ageing research reviews, 79 p. 101650. Peer-reviewed.
 
Role of glucocorticoid receptor mutations in hypertension and adrenal gland hyperplasia.
Verouti S., Hummler E., Vanderriele P.E., 2022/08. Pflugers Archiv, 474 (8) pp. 829-840. Peer-reviewed.
Emotional Intelligence in Ultra-Marathon Runners: Implications for Recovery Strategy and Stress Responses during an Ultra-Endurance Race.
Nicolas M., Gaudino M., Bagneux V., Millet G., Laborde S., Martinent G., 2022/07/29. International journal of environmental research and public health, 19 (15). Peer-reviewed.
Entraînement avec occlusion vasculaire: mécanismes et applications [Exercise training with blood flow restriction : mechanisms and applications]
Guedria M., Besson C., Millet G.P., Gremeaux V., 2022/07/20. Revue medicale suisse, 18 (790-2) pp. 1464-1469. Peer-reviewed.
Small RNAs derived from tRNA fragmentation regulate the functional maturation of neonatal β cells.
Bayazit M.B., Jacovetti C., Cosentino C., Sobel J., Wu K., Brozzi F., Rodriguez-Trejo A., Stoll L., Guay C., Regazzi R., 2022/07/12. Cell reports, 40 (2) p. 111069. Peer-reviewed.
 
Bisphenol S favors hepatic steatosis development via an upregulation of liver MCT1 expression and an impairment of the mitochondrial respiratory system.
Mornagui B., Rezg R., Repond C., Pellerin L., 2022/07. Journal of cellular physiology, 237 (7) pp. 3057-3068. Peer-reviewed.
Commentaries on Viewpoint: Using V̇o 2max as a marker of training status in athletes - can we do better?
Valenzuela P.L., Mateo-March M., Muriel X., Zabala M., Lucia A., Barranco-Gil D., Millet G.P., Brocherie F., Burtscher J., Burtscher M. et al., 2022/07/01. Journal of applied physiology, 133 (1) pp. 148-164. Peer-reviewed.
Human IPSC 3D brain model as a tool to study chemical-induced dopaminergic neuronal toxicity.
Pamies D., Wiersma D., Katt M.E., Zhao L., Burtscher J., Harris G., Smirnova L., Searson P.C., Hartung T., Hogberg H.T., 2022/07. Neurobiology of disease, 169 p. 105719. Peer-reviewed.
 
Mineralocorticoid Receptor Antagonists Cause Natriuresis in the Absence of Aldosterone.
Maeoka Y., Su X.T., Wang W.H., Duan X.P., Sharma A., Li N., Staub O., McCormick J.A., Ellison D.H., 2022/07. Hypertension, 79 (7) pp. 1423-1434. Peer-reviewed.
The interplay of hypoxic and mental stress: Implications for anxiety and depressive disorders.
Burtscher J., Niedermeier M., Hüfner K., van den Burg E., Kopp M., Stoop R., Burtscher M., Gatterer H., Millet G.P., 2022/07. Neuroscience and biobehavioral reviews, 138 p. 104718. Peer-reviewed.
Analysis of the Hypoxic Response in a Mouse Cortical Collecting Duct-Derived Cell Line Suggests That Esrra Is Partially Involved in Hif1α-Mediated Hypoxia-Inducible Gene Expression in mCCD<sub>cl1</sub> Cells.
Keppner A., Maric D., Orlando IMC, Falquet L., Hummler E., Hoogewijs D., 2022/06/30. International journal of molecular sciences, 23 (13). Peer-reviewed.
 
The EnvZ/OmpR Two-Component System Regulates the Antimicrobial Activity of TAT-RasGAP<sub>317-326</sub> and the Collateral Sensitivity to Other Antibacterial Agents.
Georgieva M., Heinonen T., Hargraves S., Pillonel T., Widmann C., Jacquier N., 2022/06/29. Microbiology spectrum, 10 (3) pp. e0200921. Peer-reviewed.
Unchanged Fatality Rate on Austrian Ski Slopes during the COVID-19 Lockdown.
Posch M., Burtscher J., Ruedl G., Pocecco E., Burtscher M., 2022/06/24. International journal of environmental research and public health, 19 (13) p. 7771. Peer-reviewed.
A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain
Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Fabrice Battison, Vanille Maillard, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch, 2022/06/21..
Kidney-Specific CAP1/Prss8-Deficient Mice Maintain ENaC-Mediated Sodium Balance through an Aldosterone Independent Pathway.
Ehret E., Jäger Y., Sergi C., Mérillat A.M., Peyrollaz T., Anand D., Wang Q., Ino F., Maillard M., Kellenberger S. et al., 2022/06/16. International journal of molecular sciences, 23 (12) p. 6745. Peer-reviewed.
Urine and Fecal 1H-NMR Metabolomes Differ Significantly between Pre-Term and Full-Term Born Physically Fit Healthy Adult Males.
Deutsch L., Debevec T., Millet G.P., Osredkar D., Opara S., Šket R., Murovec B., Mramor M., Plavec J., Stres B., 2022/06/10. Metabolites, 12 (6). Peer-reviewed.
An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.
Nunes C., Singh P., Mazidi Z., Murphy C., Bourguignon A., Wellens S., Chandrasekaran V., Ghosh S., Zana M., Pamies D. et al., 2022/06. Toxicology in vitro, 81 p. 105333. Peer-reviewed.
 
Cellular reprogramming and the rise of rejuvenation biotech.
de Magalhães J.P., Ocampo A., 2022/06. Trends in biotechnology, 40 (6) pp. 639-642. Peer-reviewed.
Effect of acute iron infusion on insulin secretion: A randomized, double-blind, placebo-controlled trial.
Jaccard E., Seyssel K., Gouveia A., Vergely C., Baratali L., Gubelmann C., Froissart M., Favrat B., Marques-Vidal P., Tappy L. et al., 2022/06. EClinicalMedicine, 48 p. 101434. Peer-reviewed.
 
Empagliflozin Changes Urine Supersaturation by Decreasing pH and Increasing Citrate.
Harmacek D., Pruijm M., Burnier M., Muller M.E., Ghajarzadeh-Wurzner A., Bonny O., Zanchi A., 2022/06. Journal of the American Society of Nephrology, 33 (6) pp. 1073-1075. Peer-reviewed.
Lessons from neonatal β-cell epigenomic for diabetes prevention and treatment.
Abderrahmani A., Jacovetti C., Regazzi R., 2022/06. Trends in endocrinology and metabolism, 33 (6) pp. 378-389. Peer-reviewed.
 
RMSSD Is More Sensitive to Artifacts Than Frequency-Domain Parameters: Implication in Athletes' Monitoring.
Bourdillon N., Yazdani S., Vesin J.M., Schmitt L., Millet G.P., 2022/06. Journal of sports science & medicine, 21 (2) pp. 260-266. Peer-reviewed.
 
Upscaling biological complexity to boost neuronal and oligodendroglia maturation and improve in vitro developmental neurotoxicity (DNT) evaluation.
Nunes C., Gorczyca G., Mendoza-deGyves E., Ponti J., Bogni A., Carpi D., Bal-Price A., Pistollato F., 2022/06. Reproductive toxicology, 110 pp. 124-140. Peer-reviewed.
Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells
Francesco Petrelli, Valentina Scandella, Sylvie Montessuit, Nicola Zamboni, Jean-Claude Martinou, Marlen Knobloch, 2022/05/31..
Alterations in spontaneous electrical brain activity after an extreme mountain ultramarathon.
Spring J.N., Sallard E.F., Trabucchi P., Millet G.P., Barral J., 2022/05. Biological psychology, 171 p. 108348. Peer-reviewed.
Does Regular Physical Activity Mitigate the Age-Associated Decline in Pulmonary Function?
Burtscher J., Millet G.P., Gatterer H., Vonbank K., Burtscher M., 2022/05. Sports medicine, 52 (5) pp. 963-970. Peer-reviewed.
ENaC activation by proteases.
Anand D., Hummler E., Rickman O.J., 2022/05. Acta physiologica, 235 (1) pp. e13811. Peer-reviewed.
 
Neuromuscular fatigability during repeated sprints assessed with an innovative cycle ergometer.
Di Domenico H., Beaume J.B., Peyrard A., Samozino P., Bowen M., Hintzy F., Millet G.P., Hayes M., Lapole T., Rupp T., 2022/05. European journal of applied physiology, 122 (5) pp. 1189-1204. Peer-reviewed.
 
The current clinical landscape of personalized cancer vaccines.
Fritah H., Rovelli R., Chiang C.L., Kandalaft L.E., 2022/05. Cancer treatment reviews, 106 p. 102383. Peer-reviewed.
The evolutionarily conserved miRNA-137 targets the neuropeptide hypocretin/orexin and modulates the wake to sleep ratio.
Holm A., Possovre M.L., Bandarabadi M., Moseholm K.F., Justinussen J.L., Bozic I., Lemcke R., Arribat Y., Amati F., Silahtaroglu A. et al., 2022/04/26. Proceedings of the National Academy of Sciences of the United States of America, 119 (17) pp. e2112225119. Peer-reviewed.
 
Discovery of a novel SHIP1 agonist that promotes degradation of lipid-laden phagocytic cargo by microglia.
Pedicone C., Fernandes S., Matera A., Meyer S.T., Loh S., Ha J.H., Bernard D., Chisholm J.D., Paolicelli R.C., Kerr W.G., 2022/04/15. iScience, 25 (4) p. 104170. Peer-reviewed.
Exercise-microbiota interactions in aging-related sarcopenia.
Burtscher J., Ticinesi A., Millet G.P., Burtscher M., Strasser B., 2022/04. Journal of cachexia, sarcopenia and muscle, 13 (2) pp. 775-780. Peer-reviewed.
Inhibition of Trpv4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism.
Tzanoulinou S., Musardo S., Contestabile A., Bariselli S., Casarotto G., Magrinelli E., Jiang Y.H., Jabaudon D., Bellone C., 2022/04. Molecular psychiatry, 27 (4) pp. 2080-2094. Peer-reviewed.
Methods for the dietary assessment of adult kidney stone formers: a scoping review.
Legay C., Krasniqi T., Bourdet A., Bonny O., Bochud M., 2022/04. Journal of nephrology, 35 (3) pp. 821-830. Peer-reviewed.
Training During the COVID-19 Lockdown: Knowledge, Beliefs, and Practices of 12,526 Athletes from 142 Countries and Six Continents.
Washif J.A., Farooq A., Krug I., Pyne D.B., Verhagen E., Taylor L., Wong D.P., Mujika I., Cortis C., Haddad M. et al., 2022/04. Sports medicine, 52 (4) pp. 933-948. Peer-reviewed.
Retrospective Analysis of Autologous Chondrocyte-Based Cytotherapy Production for Clinical Use: GMP Process-Based Manufacturing Optimization in a Swiss University Hospital.
Philippe V., Laurent A., Hirt-Burri N., Abdel-Sayed P., Scaletta C., Schneebeli V., Michetti M., Brunet J.F., Applegate L.A., Martin R., 2022/03/17. Cells, 11 (6) p. 1016. Peer-reviewed.
Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease.
Jouffe C., Weger B.D., Martin E., Atger F., Weger M., Gobet C., Ramnath D., Charpagne A., Morin-Rivron D., Powell E.E. et al., 2022/03/08. Proceedings of the National Academy of Sciences of the United States of America, 119 (10) pp. e2200083119. Peer-reviewed.
Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia.
Cramer T., Gill R., Thirouin Z.S., Vaas M., Sampath S., Martineau F., Noya S.B., Panzanelli P., Sudharshan TJJ, Colameo D. et al., 2022/03/04. Science advances, 8 (9) pp. eabj0112. Peer-reviewed.
Hyperuricémie et maladie rénale : prise en charge [Management of hyperuricemia in chronic kidney disease]
Schwotzer N., Auberson M., Livio F., So A., Bonny O., 2022/03/02. Revue medicale suisse, 18 (771) pp. 379-384. Peer-reviewed.
 
Commentaries on Viewpoint: Consider iron status when making sex comparisons in human physiology.
Badenhorst C.E., Millet G.P., Debevec T., Brocherie F., Coates A.M., Burr J.F., Andersen A.B., Bejder J., Gliemann L., Pedlar C.R. et al., 2022/03/01. Journal of applied physiology, 132 (3) pp. 703-709. Peer-reviewed.
 
Dysfunction of the circadian clock in the kidney tubule leads to enhanced kidney gluconeogenesis and exacerbated hyperglycemia in diabetes.
Ansermet C., Centeno G., Bignon Y., Ortiz D., Pradervand S., Garcia A., Menin L., Gachon F., Yoshihara H.A., Firsov D., 2022/03. Kidney international, 101 (3) pp. 563-573. Peer-reviewed.
HDLs extract lipophilic drugs from cells.
Zheng A., Dubuis G., Georgieva M., Mendes Ferreira C.S., Serulla M., Del Carmen Conde Rubio M., Trofimenko E., Mercier T., Decosterd L., Widmann C., 2022/03/01. Journal of cell science, 135 (5) pp. jcs258644. Peer-reviewed.
LMOD3 gene variant in familial periodic hypersomnolence.
Wenz E., Tafti M., Bassetti CLA, 2022/03. Sleep medicine, 91 pp. 105-108. Peer-reviewed.
 
Microglial metabolic flexibility: emerging roles for lactate.
Monsorno K., Buckinx A., Paolicelli R.C., 2022/03. Trends in endocrinology and metabolism, 33 (3) pp. 186-195. Peer-reviewed.
 
Post-exercise accumulation of interstitial lung water is greater in hypobaric than normobaric hypoxia in adults born prematurely.
Debevec T., Poussel M., Osredkar D., Willis S.J., Sartori C., Millet G.P., 2022/03. Respiratory physiology & neurobiology, 297 p. 103828. Peer-reviewed.
Gd3+-Functionalized Lithium Niobate Nanoparticles for Dual Multiphoton and Magnetic Resonance Bioimaging.
De Matos Raphaël, Gheata Adrian, Campargue Gabriel, Vuilleumier Jérémy, Nicolle Laura, Pierzchala Katarzyna, Jelescu Ileana, Lucarini Fiorella, Gautschi Ivan, Riporto Florian et al., 2022/02/25. ACS Applied Nano Materials, 5 (2) pp. 2912-2922.
 
Renal tubular peroxisomes are dispensable for normal kidney function.
Ansermet C., Centeno G., Pradervand S., Harmacek D., Garcia A., Daraspe J., Kocherlakota S., Baes M., Bignon Y., Firsov D., 2022/02/22. JCI insight, 7 (4) pp. e155836. Peer-reviewed.
Mechanisms Underlying the Expansion and Functional Maturation of β-Cells in Newborns: Impact of the Nutritional Environment.
Jacovetti C., Regazzi R., 2022/02/14. International journal of molecular sciences, 23 (4) p. 2096. Peer-reviewed.
APOBEC3C, a nucleolar protein induced by genotoxins, is excluded from DNA damage sites.
Constantin D., Dubuis G., Conde-Rubio MDC, Widmann C., 2022/02. The FEBS journal, 289 (3) pp. 808-831. Peer-reviewed.
Brain lipid metabolism: the emerging role of lipid droplets in glial cells.
Petrelli F., Knobloch M., Amati F., 2022/02/01. Current opinion in lipidology, 33 (1) pp. 86-87. Peer-reviewed.
Does the early aldosterone-induced SGK1 play a role in early Kaliuresis?
Al-Qusairi L., Basquin D., Stifanelli M., Welling P.A., Staub O., 2022/02. Physiological reports, 10 (4) pp. e15188. Peer-reviewed.
Effect of very large body mass loss on energetics, mechanics and efficiency of walking in adults with obesity: mass-driven versus behavioural adaptations.
Malatesta D., Favre J., Ulrich B., Hans D., Suter M., Favre L., Fernández Menéndez A., 2022/02. The Journal of physiology, 600 (4) pp. 979-996. Peer-reviewed.
From In Vitro Data to In Vivo Interspecies Danger Communication: A Study of Chemosensing via the Mouse Grueneberg Ganglion.
Lopes A.C., Brechbühl J., Ferreira F., Amez-Droz M., Broillet M.C., 2022/02/01. Animals, 12 (3) p. 356. Peer-reviewed.
 
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.
Spînu N., Cronin MTD, Lao J., Bal-Price A., Campia I., Enoch S.J., Madden J.C., Mora Lagares L., Novič M., Pamies D. et al., 2022/02. Computational toxicology, 21 p. 100206. Peer-reviewed.
 
Towards a qAOP framework for predictive toxicology - Linking data to decisions.
Paini A., Campia I., Cronin MTD, Asturiol D., Ceriani L., Exner T.E., Gao W., Gomes C., Kruisselbrink J., Martens M. et al., 2022/02. Computational toxicology, 21 p. 100195. Peer-reviewed.
Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis.
Czepiel M., Diviani D., Jaźwa-Kusior A., Tkacz K., Rolski F., Smolenski R.T., Siedlar M., Eriksson U., Kania G., Błyszczuk P., 2022/01/29. Cardiovascular research, 118 (2) pp. 573-584. Peer-reviewed.
Adiponectin levels and its relation with insulin secretion and insulin sensitivity in a group of sub-Saharan African women with polycystic ovary syndrome.
Momo A.S., Ama Moor V.J., Tankeu A.T., Amazia F., Sadeu Wafeu G., Guewo-Fokeng M., Mbono Samba E.A., Nkeck J.R., Djieka Y., Chemaga Nkonpawa C. et al., 2022/01/28. BMC research notes, 15 (1) p. 24. Peer-reviewed.
Acute decrease of urine calcium by amiloride in healthy volunteers under high-sodium diet.
Harmacek D., Blanchard A., Wuerzner G., Maillard M., Jeunemaitre X., Azizi M., Bonny O., 2022/01/25. Nephrology, dialysis, transplantation, 37 (2) pp. 298-303. Peer-reviewed.
Effects of Pre-Term Birth on the Cardio-Respiratory Responses to Hypoxic Exercise in Children.
Narang B.J., Manferdelli G., Kepic K., Sotiridis A., Osredkar D., Bourdillon N., Millet G.P., Debevec T., 2022/01/06. Life, 12 (1) p. 79. Peer-reviewed.
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