Centre for Integrative Genomics

CIG Services communs | Groupe Benton | Groupe Fajas | Groupe Fankhauser | Groupe Franken | Groupe Gambetta | Groupe Gatfield | Groupe Larsch | Groupe Michalik | Groupe Reymond | Groupe Roignant | Groupe van Leeuwen | Groupe Vastenhouw | Groupe Vjestica | Plateforme de biostatistique | Plateforme Genomics Technologies Facility (GTF) | Plateforme Protein Analysis Facility (PAF)
Publications | Phd and Masters theses

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13 publications

2023 | 2022 | 2021 | 2020 | 2019 | 2018 |
2023
 
Hepatic lipid overload triggers biliary epithelial cell activation via E2Fs.
Yildiz E., El Alam G., Perino A., Jalil A., Denechaud P.D., Huber K., Fajas L., Auwerx J., Sorrentino G., Schoonjans K., 2023/03/06. eLife, 12 pp. e81926. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_8530865240EA]
Oxidative stress-induced FAK activation contributes to uterine serous carcinoma aggressiveness.
Lopez-Mejia I.C., Pijuan J., Navaridas R., Santacana M., Gatius S., Velasco A., Castellà G., Panosa A., Cabiscol E., Pinyol M. et al., 2023/01. Molecular oncology, 17 (1) pp. 98-118. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_549BE66DECEF]
2022
Adipocyte-specific CDK7 ablation leads to progressive loss of adipose tissue and metabolic dysfunction.
Chen Y., Fernandez E.A., Roger C., Lopez-Mejia I.C., Fajas Coll L., Ji H., 2022/06. FEBS letters, 596 (11) pp. 1434-1444. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C1D722D17E1D]
2021
 
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Lacroix M., Linares L.K., Rueda-Rincon N., Bloch K., Di Michele M., De Blasio C., Fau C., Gayte L., Blanchet E., Mairal A. et al., 2021/12/02. Nature communications, 12 (1) p. 7037. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_9A257A1F04A8]
The multifaceted role of cell cycle regulators in the coordination of growth and metabolism.
Huber K., Mestres-Arenas A., Fajas L., Leal-Esteban L.C., 2021/06. The FEBS journal, 288 (12) pp. 3813-3833. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_71F450E7C4FC]
2020
 
Tumor regression and resistance mechanisms upon CDK4 and RAF1 inactivation in KRAS/P53 mutant lung adenocarcinomas.
Esteban-Burgos L., Wang H., Nieto P., Zheng J., Blanco-Aparicio C., Varela C., Gómez-López G., Fernández-García F., Sanclemente M., Guerra C. et al., 2020/09/29. Proceedings of the National Academy of Sciences of the United States of America, 117 (39) pp. 24415-24426. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_05519E55AA11]
 
Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.
Castillo-Armengol J., Barquissau V., Geller S., Ji H., Severi I., Venema W., Fenandez E.A., Moret C., Huber K., Leal-Esteban L.C. et al., 2020/09/03. EMBO reports, 21 (9) pp. e49807. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BA842E7BA291]
 
CDK7 Mediates the Beta-Adrenergic Signaling in Thermogenic Brown and White Adipose Tissues.
Ji H., Chen Y., Castillo-Armengol J., Dreos R., Moret C., Niederhäuser G., Delacuisine B., Lopez-Mejia I.C., Denechaud P.D., Fajas L., 2020/06/26. iScience, 23 (6) p. 101163. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EBF3BB5349A2]
2019
 
CDK4 Regulates Lysosomal Function and mTORC1 Activation to Promote Cancer Cell Survival.
Martínez-Carreres L., Puyal J., Leal-Esteban L.C., Orpinell M., Castillo-Armengol J., Giralt A., Dergai O., Moret C., Barquissau V., Nasrallah A. et al., 2019/10/15. Cancer research, 79 (20) pp. 5245-5259. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A55F9416C381]
 
Inter-organ communication: a gatekeeper for metabolic health.
Castillo-Armengol J., Fajas L., Lopez-Mejia I.C., 2019/09. EMBO reports, 20 (9) pp. e47903. Peer-reviewed.
[DOI][Pmid][serval:BIB_3D85056E88C8]
2018
E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes.
Giralt A., Denechaud P.D., Lopez-Mejia I.C., Delacuisine B., Blanchet E., Bonner C., Pattou F., Annicotte J.S., Fajas L., 2018/05. Molecular metabolism, 11 pp. 104-112. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_ED95377F8A23]
 
Role of cell cycle regulators in adipose tissue and whole body energy homeostasis.
Lopez-Mejia I.C., Castillo-Armengol J., Lagarrigue S., Fajas L., 2018/03. Cellular and molecular life sciences, 75 (6) pp. 975-987. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_D70173D2EEC9]
CDK4, a new metabolic sensor that antagonizes AMPK.
Fajas L., Lopez-Mejia I.C., 2018. Molecular & cellular oncology, 5 (5) pp. e1409862. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_31B3469F93CE]
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