Centre intégratif de génomique

Equipe principale | CIG Services communs | Groupe Benton | Groupe Fajas | Groupe Fankhauser | Groupe Franken | Groupe Gambetta | Groupe Gatfield | Groupe Larsch | Groupe Michalik | Groupe Reymond | Groupe Roignant | Groupe van Leeuwen | Groupe Vastenhouw | Groupe Vjestica | Plateforme de biostatistique | Plateforme Genomics Technologies Facility (GTF) | Plateforme Protein Analysis Facility (PAF)
Publications | Mémoires et thèses

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1733 publications

... | 2011 | 2010 | 2009 | ...
2011
Comparison of Strategies to Detect Epistasis from eQTL Data.
Kapur K., Schüpbach T., Xenarios I., Kutalik Z., Bergmann S., 2011. PLoS One, 6 (12) pp. e28415.
[URN][DOI][WoS][Pmid][serval:BIB_AD05BDDCB787]
Complementary function and integrated wiring of the evolutionarily distinct Drosophila olfactory subsystems.
Silbering A.F., Rytz R., Grosjean Y., Abuin L., Ramdya P., Jefferis G.S., Benton R., 2011. Journal of Neuroscience, 31 (38) pp. 13357-13375.
[URN][DOI][WoS][Pmid][serval:BIB_10314C79D282]
Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees.
Boeckmann B., Robinson-Rechavi M., Xenarios I., Dessimoz C., 2011. Briefings in Bioinformatics, 12 (5) pp. 423-435. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3EF9A7BDC38C]
Cooperative kinking at distant sites in mechanically stressed DNA.
Lionberger T.A., Demurtas D., Witz G., Dorier J., Lillian T., Meyhöfer E., Stasiak A., 2011. Nucleic Acids Research, 39 (22) pp. 9820-9832.
[URN][DOI][WoS][Pmid][serval:BIB_AAD051219F59]
 
Copy number variation modifies expression time courses.
Chaignat E., Yahya-Graison E.A., Henrichsen C.N., Chrast J., Schütz F., Pradervand S., Reymond A., 2011. Genome Research, 21 (1) pp. 106-113.
[DOI][WoS][Pmid][serval:BIB_F86987ABB7C7]
 
Cumulative Shapes of Knotted Polymers
Rawdon Eric J., Millett Kenneth C., Tran Vy T., Stasiak Andrzej, 2011. Progress of Theoretical Physics Supplement, 191 pp. 165-171. Peer-reviewed.
[WoS][serval:BIB_E3E207286AFD]
 
Decision making: singin' in the brain.
Benton R., 2011. Neuron, 69 (3) pp. 399-401.
[DOI][WoS][Pmid][serval:BIB_E9477F5D6B32]
Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects.
Romero Y., Meikar O., Papaioannou M.D., Conne B., Grey C., Weier M., Pralong F., De Massy B., Kaessmann H., Vassalli J.D. et al., 2011. PLoS One, 6 (10) pp. e25241.
[URN][DOI][WoS][Pmid][serval:BIB_C14CDFC8DC83]
 
DNA knots and DNA supercoiling.
Witz G., Dietler G., Stasiak A., 2011. Cell Cycle, 10 (9) pp. 1339 - 1340.
[DOI][WoS][Pmid][serval:BIB_D0B3B4E4B323]
 
Draft genome of the globally widespread and invasive Argentine ant (Linepithema humile).
Smith C.D., Zimin A., Holt C., Abouheif E., Benton R., Cash E., Croset V., Currie C.R., Elhaik E., Elsik C.G. et al., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (14) pp. 5673-5678.
[DOI][WoS][Pmid][serval:BIB_310440611FA0]
 
Draft genome of the red harvester ant Pogonomyrmex barbatus.
Smith C.R., Smith C.D., Robertson H.M., Helmkampf M., Zimin A., Yandell M., Holt C., Hu H., Abouheif E., Benton R. et al., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (14) pp. 5667-5672.
[DOI][WoS][Pmid][serval:BIB_61F97E30A96E]
Drosophila melanogaster dHCF Interacts with both PcG and TrxG Epigenetic Regulators.
Rodriguez-Jato S., Busturia A., Herr W., 2011. PLoS One, 6 (12) pp. e27479.
[URN][DOI][WoS][Pmid][serval:BIB_0B43BEBE64F0]
 
Electrophysiological recording from Drosophila olfactory sensilla.
Benton R., Dahanukar A., 2011. Cold Spring Harbor Protocols, 2011 (7) pp. 824-838.
[DOI][Pmid][serval:BIB_F2A1E1087EED]
 
Electrophysiological recording from Drosophila taste sensilla.
Benton R., Dahanukar A., 2011. Cold Spring Harbor Protocols, 2011 (7) pp. 839-850.
[DOI][Pmid][serval:BIB_9525DE76977C]
 
Endocrine disruptors: from endocrine to metabolic disruption.
Casals-Casas C., Desvergne B., 2011. Annual Review of Physiology, 73 pp. 135-162.
[DOI][WoS][Pmid][serval:BIB_048D181C6B37]
Functional architecture of olfactory ionotropic glutamate receptors.
Abuin L., Bargeton B., Ulbrich M.H., Isacoff E.Y., Kellenberger S., Benton R., 2011. Neuron, 69 (1) pp. 44-60.
[URN][DOI][WoS][Pmid][serval:BIB_62747B9FEB54]
 
Genetic basis of sleep in rodents
O'Hara B.F., Turek F.W., Franken P., 2011. pp. 161-174 dans Kryger M.H., Roth T., Dement W.C. (eds.) Principles and practice of sleep medicine chap. 14, Elsevier Saunders.
[serval:BIB_2ED4805B98BE]
 
Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis.
Faivre E., Gault V.A., Thorens B., Hölscher C., 2011. Journal of Neurophysiology, 105 (4) pp. 1574-1580.
[DOI][WoS][Pmid][serval:BIB_CBB8AAFE016B]
 
Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.
Kulozik P., Jones A., Mattijssen F., Rose A.J., Reimann A., Strzoda D., Kleinsorg S., Raupp C., Kleinschmidt J., Müller-Decker K. et al., 2011. Cell Metabolism, 13 (4) pp. 389-400.
[DOI][WoS][Pmid][serval:BIB_6BF81573AFFB]
Homeodomain binding motifs modulate the probability of odorant receptor gene choice in transgenic mice.
Vassalli A., Feinstein P., Mombaerts P., 2011. Molecular and Cellular Neuroscience, 46 (2) pp. 381-396.
[URN][DOI][WoS][Pmid][serval:BIB_A74DE94AE004]
 
Identification of novel secreted proteases during extracellular proteolysis by dermatophytes at acidic pH.
Sriranganadane D., Waridel P., Salamin K., Feuermann M., Mignon B., Staib P., Neuhaus J.M., Quadroni M., Monod M., 2011. Proteomics, 11 (22) pp. 4422-4433.
[DOI][WoS][Pmid][serval:BIB_F007F4C7B959]
 
Immuno-reactive proteins from Mycobacterium immunogenum useful for serodiagnosis of metalworking fluid hypersensitivity pneumonitis.
Roussel S., Rognon B., Barrera C., Reboux G., Salamin K., Grenouillet F., Thaon I., Dalphin J.C., Tillie-Leblond I., Quadroni M. et al., 2011. International Journal of Medical Microbiology, 301 (2) pp. 150-156.
[DOI][WoS][Pmid][serval:BIB_05CF4E818A71]
 
Improvement of migraine headaches in severely obese patients after bariatric surgery.
Haba-Rubio J., Tafti M., Heinzer R., Bond D.S., Wing R.R., 2011. Neurology, 77 (19) pp. 1772-3; author reply 1773.
[DOI][WoS][Pmid][serval:BIB_F7F84D0FF3CE]
In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.
Hu He K.H., Lorenzo P.I., Brun T., Jimenez Moreno C.M., Aeberhard D., Vallejo Ortega J., Cornu M., Thorel F., Gjinovci A., Thorens B. et al., 2011. Diabetes, 60 (6) pp. 1705-1715.
[URN][DOI][WoS][Pmid][serval:BIB_0D2579782668]
 
La nutrigénomique dans votre assiette
Wahli W., Constantin N, 2011. 212, De Boeck.
[serval:BIB_EBF62F0338A7]
 
Light receptor action is critical for maintaining plant biomass at warm ambient temperatures.
Foreman J., Johansson H., Hornitschek P., Josse E.M., Fankhauser C., Halliday K.J., 2011. Plant Journal, 65 (3) pp. 441-452.
[DOI][WoS][Pmid][serval:BIB_2FB506FFC60F]
 
Light-mediated polarization of the PIN3 auxin transporter for the phototropic response in Arabidopsis.
Ding Z., Galván-Ampudia C.S., Demarsy E., Łangowski Ł., Kleine-Vehn J., Fan Y., Morita M.T., Tasaka M., Fankhauser C., Offringa R. et al., 2011. Nature Cell Biology, 13 (4) pp. 447-452.
[DOI][WoS][Pmid][serval:BIB_FD8A42B083ED]
Light-regulated interactions with SPA proteins underlie cryptochrome-mediated gene expression.
Fankhauser C., Ulm R., 2011. Genes and Development, 25 (10) pp. 1004-1009.
[URN][DOI][WoS][Pmid][serval:BIB_D2D792964714]
 
MAF1: a new target of mTORC1.
Michels A.A., 2011. Biochemical Society Transactions, 39 (2) pp. 487-491. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6DE280385290]
 
Mammalian genes are transcribed with widely different bursting kinetics.
Suter D.M., Molina N., Gatfield D., Schneider K., Schibler U., Naef F., 2011. Science, 332 (6028) pp. 472-474.
[DOI][WoS][Pmid][serval:BIB_46FF0CE7D3AB]
Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats.
Deblon N., Veyrat-Durebex C., Bourgoin L., Caillon A., Bussier A.L., Petrosino S., Piscitelli F., Legros J.J., Geenen V., Foti M. et al., 2011. PLoS One, 6 (9) pp. e25565.
[URN][DOI][WoS][Pmid][serval:BIB_7DCA8908F3F8]
Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus.
Jacquemont S., Reymond A., Zufferey F., Harewood L., Walters R.G., Kutalik Z., Martinet D., Shen Y., Valsesia A., Beckmann N.D. et al., 2011. Nature, 478 (7367) pp. 97-102.
[URN][DOI][WoS][Pmid][serval:BIB_9700E363D9A2]
Mutation spectrum of MLL2 in a cohort of Kabuki syndrome patients.
Micale L., Augello B., Fusco C., Selicorni A., Loviglio M.N., Silengo M.C., Reymond A., Gumiero B., Zucchetti F., D'Addetta E.V. et al., 2011. Orphanet Journal of Rare Diseases, 6 (1) p. 38.
[URN][DOI][WoS][Pmid][serval:BIB_819A054F1309]
 
Narcolepsie avec cataplexie après vaccination anti-H1N1
Haba-Rubio J., Rossetti A.O., Tafti M., Heinzer R., 2011. Revue Neurologique, 167 (8-9) pp. 563-566.
[DOI][WoS][Pmid][serval:BIB_3DF57C39E182]
NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.
Yamamoto H., Williams E.G., Mouchiroud L., Cantó C., Fan W., Downes M., Héligon C., Barish G.D., Desvergne B., Evans R.M. et al., 2011. Cell, 147 (4) pp. 827-839.
[URN][DOI][WoS][Pmid][serval:BIB_5C22DA50B7A1]
Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma.
Valsesia A., Rimoldi D., Martinet D., Ibberson M., Benaglio P., Quadroni M., Waridel P., Gaillard M., Pidoux M., Rapin B. et al., 2011. PLoS One, 6 (4) pp. e18369. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5E0D3CDAAC7D]
New gene functions in megakaryopoiesis and platelet formation.
Gieger C., Radhakrishnan A., Cvejic A., Tang W., Porcu E., Pistis G., Serbanovic-Canic J., Elling U., Goodall A.H., Labrune Y. et al., 2011. Nature, 480 (7376) pp. 201-208.
[URN][DOI][WoS][Pmid][serval:BIB_5793840A79A2]
 
New insights into the role of PPARs.
Montagner A., Rando G., Degueurce G., Leuenberger N., Michalik L., Wahli W., 2011. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 85 (5) pp. 235-243. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_AD83D596CCB8]
Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice.
Thorel F., Damond N., Chera S., Wiederkehr A., Thorens B., Meda P., Wollheim C.B., Herrera P.L., 2011. Diabetes, 60 (11) pp. 2872-2882.
[URN][DOI][WoS][Pmid][serval:BIB_16B62B557AAA]
 
Nullification of small knots
Ernst Claus, Montemayor Anthony, Stasiak Andrzej, 2011. Progress of Theoretical Physics Supplement, 191 pp. 66-77. Peer-reviewed.
[WoS][serval:BIB_DB7A53E81CD2]
 
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1.
Capotosti F., Guernier S., Lammers F., Waridel P., Cai Y., Jin J., Conaway J.W., Conaway R.C., Herr W., 2011. Cell, 144 (3) pp. 376-388.
[DOI][WoS][Pmid][serval:BIB_AD874A25FC24]
 
Of fat, β cells, and diabetes.
Thorens B., 2011. Cell Metabolism, 14 (4) pp. 439-440.
[DOI][WoS][Pmid][serval:BIB_420709167259]
Ongoing and future developments at the Universal Protein Resource.
UniProt Consortium, 2011. Nucleic Acids Research, 39 (Database issue) pp. D214-D219.
[URN][DOI][WoS][Pmid][serval:BIB_57C005D9B9A1]
Oxidative phosphorylation flexibility in the liver of mice resistant to high-fat diet-induced hepatic steatosis.
Poussin C., Ibberson M., Hall D., Ding J., Soto J., Abel E.D., Thorens B., 2011. Diabetes, 60 (9) pp. 2216-2224.
[URN][DOI][WoS][Pmid][serval:BIB_90E2A4ED2946]
 
PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.
Becattini B., Marone R., Zani F., Arsenijevic D., Seydoux J., Montani J.P., Dulloo A.G., Thorens B., Preitner F., Wymann M.P. et al., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (42) pp. E854-E863.
[DOI][WoS][Pmid][serval:BIB_F18D7780E975]
 
PIDD orchestrates translesion DNA synthesis in response to UV irradiation.
Logette E., Schuepbach-Mallepell S., Eckert M.J., Leo X.H., Jaccard B., Manzl C., Tardivel A., Villunger A., Quadroni M., Gaide O. et al., 2011. Cell Death and Differentiation, 18 (6) pp. 1036-1045.
[DOI][WoS][Pmid][serval:BIB_116367F1BB36]
 
Plac8 is an inducer of C/EBPβ required for brown fat differentiation, thermoregulation, and control of body weight.
Jimenez-Preitner M., Berney X., Uldry M., Vitali A., Cinti S., Ledford J.G., Thorens B., 2011. Cell Metabolism, 14 (5) pp. 658-670.
[DOI][WoS][Pmid][serval:BIB_9E6C78808E97]
 
PPARβ/δ activation blocks lipid-induced inflammatory pathways in mouse heart and human cardiac cells.
Alvarez-Guardia D., Palomer X., Coll T., Serrano L., Rodríguez-Calvo R., Davidson M.M., Merlos M., El Kochairi I., Michalik L., Wahli W. et al., 2011. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 1811 (2) pp. 59-67. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BA4367033263]
 
Priming for enhanced defence responses by specific inhibition of the Arabidopsis response to coronatine.
Tsai C.H., Singh P., Chen C.W., Thomas J., Weber J., Mauch-Mani B., Zimmerli L., 2011. Plant Journal, 65 (3) pp. 469-479.
[DOI][WoS][Pmid][serval:BIB_F797A10ADCC6]
Proline- and acidic amino acid-rich basic leucine zipper proteins modulate peroxisome proliferator-activated receptor alpha (PPAR alpha) activity.
Gachon F., Leuenberger N., Claudel T., Gos P., Jouffe C., Fleury Olela F., de Mollerat du Jeu X., Wahli W., Schibler U., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (12) pp. 4794-4799. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2BE2B46D7941]
 
Regulation of PIDD auto-proteolysis and activity by the molecular chaperone Hsp90.
Tinel A., Eckert M.J., Logette E., Lippens S., Janssens S., Jaccard B., Quadroni M., Tschopp J., 2011. Cell Death and Differentiation, 18 (3) pp. 506-515.
[DOI][WoS][Pmid][serval:BIB_8464B140CE34]
 
Role of topological exclusion in formation and organization of chromosomal territories
Dorier Julien, Stasiak Andrzej, 2011. Progress of Theoretical Physics Supplement, 191 pp. 46-54. Peer-reviewed.
[WoS][serval:BIB_2E510889DD8C]
 
Searching for Novel Cellular Targets of the Hepatitis C Virus NS3-4A Protease
Morikawa K., Gouttenoire J., Bellecave P., Lange C.M., Kennel A., Quadroni M., Moradpour D., 2011. pp. 19S dans Annual Meeting of the Swiss Society of Gastroenterology, Swiss Society for Visceral Surgery, Swiss Association for the Study of the Liver, Swiss Medical Weekly. Peer-reviewed.
[serval:BIB_EE36F1DD6227]
 
Secreted glutamic protease rescues aspartic protease Pep deficiency in Aspergillus fumigatus during growth in acidic protein medium.
Sriranganadane D., Reichard U., Salamin K., Fratti M., Jousson O., Waridel P., Quadroni M., Neuhaus J.M., Monod M., 2011. Microbiology, 157 (5) pp. 1541-1550.
[DOI][WoS][Pmid][serval:BIB_7635EE1ACA3D]
 
Sex differences in nuclear receptor-regulated liver metabolic pathways.
Rando G., Wahli W., 2011. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1812 (8) pp. 964-973. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1D967EDCCDB2]
Sleep loss reduces the DNA-binding of BMAL1, CLOCK, and NPAS2 to specific clock genes in the mouse cerebral cortex.
Mongrain V., La Spada F., Curie T., Franken P., 2011. PLoS One, 6 (10) pp. e26622.
[URN][DOI][WoS][Pmid][serval:BIB_2F8381649979]
Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet.
Tan C.K., Leuenberger N., Tan M.J., Yan Y.W., Chen Y., Kambadur R., Wahli W., Tan N.S., 2011. Diabetes, 60 (2) pp. 464-476. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2494301CF2DB]
 
Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts.
Ge X., McFarlane C., Vajjala A., Lokireddy S., Ng Z.H., Tan C.K., Tan N.S., Wahli W., Sharma M., Kambadur R., 2011. Cell Research, 21 (11) pp. 1591-1604.
[DOI][WoS][Pmid][serval:BIB_74153695E96D]
Source inference of exogenous gamma-hydroxybutyric acid (GHB) administered to humans by means of carbon isotopic ratio analysis: novel perspectives regarding forensic investigation and intelligence issues.
Marclay F., Saudan C., Vienne J., Tafti M., Saugy M., 2011. Analytical and Bioanalytical Chemistry, 400 (4) pp. 1105-1112.
[URN][DOI][WoS][Pmid][serval:BIB_73D5CEFCC8A5]
T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension.
Di Tommaso P., Moretti S., Xenarios I., Orobitg M., Montanyola A., Chang J.M., Taly J.F., Notredame C., 2011. Nucleic Acids Research, 39 (Web Server issue) pp. W13-W17.
[URN][DOI][Pmid][serval:BIB_EE8EDC0ACBE8]
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.
Garrido-Urbani S., Jemelin S., Deffert C., Carnesecchi S., Basset O., Szyndralewiez C., Heitz F., Page P., Montet X., Michalik L. et al., 2011. PloS One, 6 (2) pp. e14665.
[URN][DOI][WoS][Pmid][serval:BIB_E36D61042E0B]
 
The Ca(V)3.3 calcium channel is the major sleep spindle pacemaker in thalamus.
Astori S., Wimmer R.D., Prosser H.M., Corti C., Corsi M., Liaudet N., Volterra A., Franken P., Adelman J.P., Lüthi A., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (33) pp. 13823-13828.
[DOI][WoS][Pmid][serval:BIB_46BD1B26C428]
 
The evolution of gene expression levels in mammalian organs.
Brawand D., Soumillon M., Necsulea A., Julien P., Csárdi G., Harrigan P., Weier M., Liechti A., Aximu-Petri A., Kircher M. et al., 2011. Nature, 478 (7369) pp. 343-348.
[DOI][WoS][Pmid][serval:BIB_82F2C6964F5B]
The genome of the fire ant Solenopsis invicta.
Wurm Y., Wang J., Riba-Grognuz O., Corona M., Nygaard S., Hunt B.G., Ingram K.K., Falquet L., Nipitwattanaphon M., Gotzek D. et al., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (14) pp. 5679-5684. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_79692FDC063A]
The inhibition of fat cell proliferation by n-3 fatty acids in dietary obese mice.
Hensler M., Bardova K., Jilkova Z.M., Wahli W., Meztger D., Chambon P., Kopecky J., Flachs P., 2011. Lipids in Health and Disease, 10 (1) p. 128.
[URN][DOI][WoS][Pmid][serval:BIB_C2A61BCE5407]
The origins, evolution, and functional potential of alternative splicing in vertebrates.
Mudge J.M., Frankish A., Fernandez-Banet J., Alioto T., Derrien T., Howald C., Reymond A., Guigó R., Hubbard T., Harrow J., 2011. Molecular Biology and Evolution, 28 (10) pp. 2949-2959.
[URN][DOI][WoS][Pmid][serval:BIB_F668C73CF97F]
 
The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence.
Lambiv W.L., Vassallo I., Delorenzi M., Shay T., Diserens A.C., Misra A., Feuerstein B., Murat A., Migliavacca E., Hamou M.F. et al., 2011. Neuro-Oncology, 13 (7) pp. 736-747. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_43FA202A8004]
 
Tightening of DNA knots by supercoiling facilitates their unknotting by type II DNA topoisomerases.
Witz G., Dietler G., Stasiak A., 2011. Proceedings of the National Academy of Sciences of the United States of America, 108 (9) pp. 3608-3611. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0770B1E1A91E]
Using transcription modules to identify expression clusters perturbed in Williams-Beuren syndrome.
Henrichsen C.N., Csárdi G., Zabot M.T., Fusco C., Bergmann S., Merla G., Reymond A., 2011. PLoS Computational Biology, 7 (1) pp. e1001054. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BAF4351682CD]
ViralZone: a knowledge resource to understand virus diversity.
Hulo C., de Castro E., Masson P., Bougueleret L., Bairoch A., Xenarios I., Le Mercier P., 2011. Nucleic Acids Research, 39 (Suppl 1) pp. D576-D582.
[URN][DOI][WoS][Pmid][serval:BIB_7B0D240FA3AA]
Visualization and quality assessment of de novo genome assemblies.
Riba-Grognuz O., Keller L., Falquet L., Xenarios I., Wurm Y., 2011. Bioinformatics, 27 (24) pp. 3425-3426. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_78E4EA5A315D]
Widespread occurrence of non-canonical transcription termination by human RNA polymerase III.
Orioli A., Pascali C., Quartararo J., Diebel K.W., Praz V., Romascano D., Percudani R., van Dyk L.F., Hernandez N., Teichmann M. et al., 2011. Nucleic Acids Research, 39 (13) pp. 5499-5512.
[URN][DOI][WoS][Pmid][serval:BIB_17DFDA5C12C3]
2010
Peroxisome proliferator-activated receptor β/δ: a master regulator of metabolic pathways in skeletal muscle.
Lahiri S., Wahli W., 2010/12/01. Hormone molecular biology and clinical investigation, 4 (2) pp. 565-573. Peer-reviewed.
[URN][DOI][Pmid][serval:BIB_DA36A39A4D6E]
Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation.
Vienne J., Bettler B., Franken P., Tafti M., 2010/10/20. The Journal of neuroscience : the official journal of the Society for Neuroscience, 30 (42) pp. 14194-14204. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DAB7E89984ED]
 
mTORC1 directly phosphorylates and regulates human MAF1.
Michels A.A., Robitaille A.M., Buczynski-Ruchonnet D., Hodroj W., Reina J.H., Hall M.N., Hernandez N., 2010/08. Molecular and cellular biology, 30 (15) pp. 3749-3757. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_EA2B2962787E]
Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene.
Kapur K., Johnson T., Beckmann N.D., Sehmi J., Tanaka T., Kutalik Z., Styrkarsdottir U., Zhang W., Marek D., Gudbjartsson D.F. et al., 2010/07/22. PLoS genetics, 6 (7) pp. e1001035. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_A16A030D2C1D]
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.
Walters R.G., Jacquemont S., Valsesia A., de Smith A.J., Martinet D., Andersson J., Falchi M., Chen F., Andrieux J., Lobbens S. et al., 2010/02/04. Nature, 463 (7281) pp. 671-675. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_779A2B29ACBA]
A comprehensive analysis of gene expression profiles in distal parts of the mouse renal tubule.
Pradervand S., Zuber Mercier A., Centeno G., Bonny O., Firsov D., 2010. Pflügers Archiv, 460 (6) pp. 925-952.
[URN][DOI][WoS][Pmid][serval:BIB_5704D6E702AC]
A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.
Yan Z., Delannoy M., Ling C., Daee D., Osman F., Muniandy P.A., Shen X., Oostra A.B., Du H., Steltenpool J. et al., 2010. Molecular Cell, 37 (6) pp. 865-878. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_48630B959492]
 
A t(7;12) balanced translocation with breakpoints overlapping those of the Williams-Beuren and 12q14 microdeletion syndromes.
Gimelli S., Chrast J., Baban A., Henrichsen C.N., Lerone M., Zuffardi O., Gimelli G., Reymond A., 2010. American Journal of Medical Genetics. Part A, 152A (5) pp. 1285-1294. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_078F653B401C]
 
Accelerated digestion for high-throughput proteomics analysis of whole bacterial proteomes.
Vaezzadeh A.R., Deshusses J.M., Waridel P., François P., Zimmermann-Ivol C.G., Lescuyer P., Schrenzel J., Hochstrasser D.F., 2010. Journal of Microbiological Methods, 80 (1) pp. 56-62.
[DOI][WoS][Pmid][serval:BIB_EDA79EF898EA]
Acid sensing by the Drosophila olfactory system.
Ai M., Min S., Grosjean Y., Leblanc C., Bell R., Benton R., Suh G.S., 2010. Nature, 468 (7324) pp. 691-695. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_416B5FB0166D]
 
An atypical 7q11.23 deletion in a normal IQ Williams-Beuren syndrome patient.
Ferrero G.B., Howald C., Micale L., Biamino E., Augello B., Fusco C., Turturo M.G., Forzano S., Reymond A., Merla G., 2010. European Journal of Human Genetics, 18 (1) pp. 33-38. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0141A423D0A6]
Ancient protostome origin of chemosensory ionotropic glutamate receptors and the evolution of insect taste and olfaction.
Croset V., Rytz R., Cummins S.F., Budd A., Brawand D., Kaessmann H., Gibson T.J., Benton R., 2010. PLoS Genetics, 6 (8) pp. e1001064. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DE35825B4655]
Animal Toxins: How is Complexity Represented in Databases?
Jungo F., Estreicher A., Bairoch A., Bougueleret L., Xenarios I., 2010. Toxins, 2 (2) pp. 262-282.
[URN][DOI][WoS][Pmid][serval:BIB_A66BBD0B1968]
 
Aspergillus protein degradation pathways with different secreted protease sets at neutral and acidic pH.
Sriranganadane D., Waridel P., Salamin K., Reichard U., Grouzmann E., Neuhaus J.-M., Quadroni M., Monod M., 2010. Journal of Proteome Research, 9 (7) pp. 3511-3519.
[DOI][WoS][Pmid][serval:BIB_E5632500E3A6]
 
CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.
Gordon V., Bhadel S., Wunderlich W., Zhang J., Ficarro S.B., Mollah S.A., Shabanowitz J., Hunt D.F., Xenarios I., Hahn W.C. et al., 2010. Molecular Endocrinology, 24 (12) pp. 2267-2280. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C1BA8B560005]
 
Central control of glucose homeostasis: the brain--endocrine pancreas axis.
Thorens B., 2010. Diabetes and Metabolism, 36 (Suppl 3) pp. S45-S49.
[DOI][WoS][Pmid][serval:BIB_E07505102FD3]
 
Central glucose sensing and the control of energy homeostasis
Thorens B., 2010. pp. S222 dans 14th International Congress of Endocrinology, Endocrine Journal. Peer-reviewed.
[WoS][serval:BIB_D8EA2E7744DA]
 
Chemosensory coding in single sensilla
Benton R., Dahanukar A., 2010. pp. ? dans Zhang B., Freeman M.R., Wadell S. (eds.) Drosophila neurobiology: a laboratory manual, Cold Spring Harbor Laboratory Press.
[serval:BIB_101639DFCEBB]
 
Chemosensory ecology: deceiving Drosophila.
Benton R., 2010. Current Biology, 20 (20) pp. R891-R893.
[DOI][WoS][Pmid][serval:BIB_0965C85A7914]
 
Comparison of three antigenic extracts of Eurotium amstelodami in serological diagnosis of farmer's lung disease.
Roussel Sandrine, Reboux Gabriel, Rognon Benedicte, Monod Michel, Grenouillet Frederic, Quadroni Manfredo, Fellrath Jean-Marc, Aubert John-David, Dalphin Jean-Charles, Millon Laurence, 2010. Clinical and Vaccine Immunology, 17 (1) pp. 160-167.
[DOI][WoS][Pmid][serval:BIB_A1EAEFDA44E9]
 
Concordance among digital gene expression, microarrays, and qPCR when measuring differential expression of microRNAs.
Pradervand S., Weber J., Lemoine F., Consales F., Paillusson A., Dupasquier M., Thomas J., Richter H., Kaessmann H., Beaudoing E. et al., 2010. Biotechniques, 48 (3) pp. 219-222.
[DOI][WoS][Pmid][serval:BIB_BCC9074E34BD]
Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination.
Buisson R., Dion-Côté A.M., Coulombe Y., Launay H., Cai H., Stasiak A.Z., Stasiak A., Xia B., Masson J.Y., 2010. Nature Structural and Molecular Biology, 17 (10) pp. 1247-1254. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F9FEB5C7E1CF]
 
Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes.
Vegiopoulos A., Müller-Decker K., Strzoda D., Schmitt I., Chichelnitskiy E., Ostertag A., Berriel Diaz M., Rozman J., Hrabe de Angelis M., Nüsing R.M. et al., 2010. Science, 328 (5982) pp. 1158-1161.
[DOI][WoS][Pmid][serval:BIB_9F3BC8E83049]
Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells.
Canella D., Praz V., Reina J.H., Cousin P., Hernandez N., 2010. Genome Research, 20 (6) pp. 710-721. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_CDA7B1F5A872]
Design of potent inhibitors of human RAD51 recombinase based on BRC motifs of BRCA2 protein: modeling and experimental validation of a chimera peptide.
Nomme J., Renodon-Cornière A., Asanomi Y., Sakaguchi K., Stasiak A.Z., Stasiak A., Norden B., Tran V., Takahashi M., 2010. Journal of Medicinal Chemistry, 53 (15) pp. 5782-5791.
[URN][DOI][WoS][Pmid][serval:BIB_501909E7F3E7]
 
Differential gene expression in the pathogenic dermatophyte Arthroderma benhamiae in vitro versus during infection.
Staib P., Zaugg C., Mignon B., Weber J., Grumbt M., Pradervand S., Harshman K., Monod M., 2010. Microbiology, 156 (Pt 3) pp. 884-895. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EDC50B528F78]
DNA supercoiling and its role in DNA decatenation and unknotting.
Witz G., Stasiak A., 2010. Nucleic Acids Research, 38 (7) pp. 2119-2133. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_0F19F8CEC35D]
 
Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth.
Furrer M., Balbi M., Albarca-Aguilera M., Gallant M., Herr W., Gallant P., 2010. Journal of Biological Chemistry, 285 (51) pp. 39623-39636. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_0D963B2F4F6E]
 
Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients.
Cvetkovic-Lopes V., Bayer L., Dorsaz S., Maret S., Pradervand S., Dauvilliers Y., Lecendreux M., Lammers G.J., Donjacour C.E., Du Pasquier R.A. et al., 2010. Journal of Clinical Investigation, 120 (3) pp. 713-719. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_6F1CF4DFB5CB]
EuroDia: a beta-cell gene expression resource.
Liechti R., Csárdi G., Bergmann S., Schütz F., Sengstag T., Boj S.F., Servitja J.M., Ferrer J., Van Lommel L., Schuit F. et al., 2010. Database, 2010 pp. baq024.
[URN][DOI][Pmid][serval:BIB_0D9E4ED81B05]
 
EuroPhenome: a repository for high-throughput mouse phenotyping data.
Morgan H., Beck T., Blake A., Gates H., Adams N., Debouzy G., Leblanc S., Lengger C., Maier H., Melvin D. et al., 2010. Nucleic Acids Research, 38 (Database issue) pp. D577-D585. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_CADC89E93E05]
 
Evolving olfactory systems on the fly.
Ramdya P., Benton R., 2010. Trends in Genetics, 26 (7) pp. 307-316.
[DOI][WoS][Pmid][serval:BIB_7DE35F34EA84]
FastEpistasis: a high performance computing solution for quantitative trait epistasis.
Schüpbach T., Xenarios I., Bergmann S., Kapur K., 2010. Bioinformatics, 26 (11) pp. 1468-1469.
[URN][DOI][WoS][Pmid][serval:BIB_CC4EF3D71E98]
From protein sequences to 3D-structures and beyond: the example of the UniProt knowledgebase.
Hinz U., UniProt Consortium, 2010. Cellular and Molecular Life Sciences, 67 (7) pp. 1049-1064.
[URN][DOI][WoS][Pmid][serval:BIB_C3142A773692]
 
Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.
Hor H., Kutalik Z., Dauvilliers Y., Valsesia A., Lammers G.J., Donjacour C.E., Iranzo A., Santamaria J., Peraita Adrados R., Vicario J.L. et al., 2010. Nature Genetics, 42 (9) pp. 786-789.
[DOI][WoS][Pmid][serval:BIB_CFB40FFC4F99]
 
Glucagon-like peptide-1 increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression.
Cornu M., Modi H., Kawamori D., Kulkarni R.N., Joffraud M., Thorens B., 2010. Journal of Biological Chemistry, 285 (14) pp. 10538-10545. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F6D8AE70F677]
 
Glucose transporters in the 21st Century.
Thorens B., Mueckler M.M., 2010. American Journal of Physiology. Endocrinology and Metabolism, 298 pp. 141-5.
[DOI][WoS][Pmid][serval:BIB_982480052E61]
 
Glut2-dependent glucose-sensing controls thermoregulation by enhancing the leptin sensitivity of NPY and POMC neurons.
Mounien L., Marty N., Tarussio D., Metref S., Genoux D., Preitner F., Foretz M., Thorens B., 2010. FASEB Journal, 24 (6) pp. 1747-1758. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F27D6E977007]
 
Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress.
Georgiadi A., Lichtenstein L., Degenhardt T., Boekschoten M.V., van Bilsen M., Desvergne B., Müller M., Kersten S., 2010. Circulation Research, 106 (11) pp. 1712-1721. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_F2FA32969620]
 
Ionotropic and metabotropic mechanisms in chemoreception: 'chance or design'?
Silbering A.F., Benton R., 2010. EMBO Reports, 11 (3) pp. 173-179.
[DOI][WoS][Pmid][serval:BIB_5185E0A6047E]
Light-induced degradation of phyA is promoted by transfer of the photoreceptor into the nucleus.
Debrieux D., Fankhauser C., 2010. Plant Molecular Biology, 73 (6) pp. 687-695. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_6198F25B8FB6]
Light-regulated plant growth and development.
Kami C., Lorrain S., Hornitschek P., Fankhauser C., 2010. Current Topics in Developmental Biology, 91 pp. 29-66.
[URN][DOI][WoS][Pmid][serval:BIB_4F05C1772CC6]
MicroRNA-122 modulates the rhythmic expression profile of the circadian deadenylase Nocturnin in mouse liver.
Kojima S., Gatfield D., Esau C.C., Green C.B., 2010. PLoS One, 5 (6) pp. e11264.
[URN][DOI][WoS][Pmid][serval:BIB_553A9D383D3E]
Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels.
Yessoufou A., Wahli W., 2010. Swiss Medical Weekly, 140 pp. w13071.
[URN][DOI][WoS][Pmid][serval:BIB_31B922B23A31]
Multiple imputations applied to the DREAM3 phosphoproteomics challenge: a winning strategy.
Guex N., Migliavacca E., Xenarios I., 2010. PLoS One, 5 (1) pp. e8012. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_2D837D79DCAA]
 
Neurochemical profile of the mouse hypothalamus using in vivo 1H MRS at 14.1T.
Lei H., Poitry-Yamate C., Preitner F., Thorens B., Gruetter R., 2010. NMR in Biomedicine, 23 (6) pp. 578-583.
[DOI][WoS][Pmid][serval:BIB_57A93519A4EC]
 
Neuroscience: Sexy circuits.
Benton R., 2010. Nature, 468 (7324) pp. 638-640.
[DOI][WoS][Pmid][serval:BIB_37EB204D6BFE]
OpenFluDB, a database for human and animal influenza virus.
Liechti R., Gleizes A., Kuznetsov D., Bougueleret L., Le Mercier P., Bairoch A., Xenarios I., 2010. Database, 2010 pp. baq004.
[URN][DOI][WoS][Pmid][serval:BIB_949FEEAB2750]
 
Origins, evolution, and phenotypic impact of new genes.
Kaessmann H., 2010. Genome Research, 20 (10) pp. 1313-1326.
[DOI][WoS][Pmid][serval:BIB_B511ED5E22FF]
 
ParA2, a Vibrio cholerae chromosome partitioning protein, forms left-handed helical filaments on DNA.
Hui M.P., Galkin V.E., Yu X., Stasiak A.Z., Stasiak A., Waldor M.K., Egelman E.H., 2010. Proceedings of the National Academy of Sciences of the United States of America, 107 (10) pp. 4590-4595.
[DOI][WoS][Pmid][serval:BIB_6FAEA31F23C9]
 
Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced pro-inflammatory state.
Hall D., Poussin C., Velagapudi V.R., Empsen C., Joffraud M., Beckmann J.S., Geerts A.E., Ravussin Y., Ibberson M., Oresic M. et al., 2010. Journal of Biological Chemistry, 285 (40) pp. 31011-31023.
[DOI][WoS][Pmid][serval:BIB_5C7339688FC7]
 
Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon.
Peyrin-Biroulet L., Beisner J., Wang G., Nuding S., Oommen S.T., Kelly D., Parmentier-Decrucq E., Dessein R., Merour E., Chavatte P. et al., 2010. Proceedings of the National Academy of Sciences of the United States of America, 107 (19) pp. 8772-8777. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A34545AA75C8]
Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models.
Ricard G., Molina J., Chrast J., Gu W., Gheldof N., Pradervand S., Schütz F., Young J.I., Lupski J.R., Reymond A. et al., 2010. PLoS Biology, 8 (11) pp. e1000543. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_034A965C3133]
 
PPAR modulation of kinase-linked receptor signaling in physiology and disease.
Rotman N., Wahli W., 2010. Physiology, 25 (3) pp. 176-185.
[DOI][WoS][Pmid][serval:BIB_8676F66989A4]
 
PPARgamma in placental angiogenesis.
Nadra K., Quignodon L., Sardella C., Joye E., Mucciolo A., Chrast R., Desvergne B., 2010. Endocrinology, 151 (10) pp. 4969-4981. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_B862E1B78613]
 
PPARα, a key regulator of hepatic energy homeostasis in health and disease
Leuenberger N., Wahli W., 2010. pp. 305-315 dans Dufour J.F., Clavien P.A. (eds.) Signaling Pathways in Liver Diseases, Springer-Verlag.
[DOI][serval:BIB_18B0CAFB2EF5]
 
Protective role of peroxisome proliferator-activated receptor-β/δ in septic shock.
Kapoor A., Shintani Y., Collino M., Osuchowski M.F., Busch D., Patel N.S., Sepodes B., Castiglia S., Fantozzi R., Bishop-Bailey D. et al., 2010. American Journal of Respiratory and Critical Care Medicine, 182 (12) pp. 1506-1515.
[DOI][WoS][Pmid][serval:BIB_0E71863AACE2]
 
Pulse Wave Amplitude Drops during Sleep are Reliable Surrogate Markers of Changes in Cortical Activity.
Delessert A., Espa F., Rossetti A., Lavigne G., Tafti M., Heinzer R., 2010. Sleep, 33 (12) pp. 1687-1692. Peer-reviewed.
[WoS][Pmid][serval:BIB_8A0CA5850710]
 
Rapid occurrence of depression following addition of sodium oxybate to modafinil.
Rossetti A.O., Heinzer R.C., Tafti M., Buclin T., 2010. Sleep Medicine, 11 (5) pp. 500-501. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_C6A89BF8D880]
Role of the HCF-1 basic region in sustaining cell proliferation.
Mangone M., Myers M.P., Herr W., 2010. PLoS One, 5 (2) pp. e9020. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_3FF92C484104]
 
Separating the contribution of glucocorticoids and wakefulness to the molecular and electrophysiological correlates of sleep homeostasis.
Mongrain V., Hernandez S.A., Pradervand S., Dorsaz S., Curie T., Hagiwara G., Gip P., Heller H.C., Franken P., 2010. Sleep, 33 (9) pp. 1147-1157.
[WoS][Pmid][serval:BIB_424653092D75]
 
Sodium oxybate is an effective and safe treatment for narcolepsy.
Lammers G.J., Bassetti C., Billiard M., Black J., Broughton R., Dauvilliers Y., Ferini Strambi L., Garcia-Borreguero D., Goswami M., Högl B. et al., 2010. Sleep Medicine, 11 (1) pp. 105-106; author reply 106-108.
[DOI][WoS][Pmid][serval:BIB_B8833F884033]
Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays.
Santuari L., Pradervand S., Amiguet-Vercher A.M., Thomas J., Dorcey E., Harshman K., Xenarios I., Juenger T.E., Hardtke C.S., 2010. Genome Biology, 11 (1) pp. R4.
[URN][DOI][WoS][Pmid][serval:BIB_5A02614F7662]
 
Symmetry-breaking in cumulative measures of shapes of polymer models.
Millett K.C., Rawdon E.J., Tran T.V., Stasiak A., 2010. Journal of Chemical Physics, 133 (15) p. 154113.
[DOI][WoS][Pmid][serval:BIB_357CEB0096EE]
SYSGENET: a meeting report from a new European network for systems genetics.
Schughart K., SYSGENET consortium, 2010. Mammalian Genome, 21 (7-8) pp. 331-336.
[URN][DOI][Pmid][serval:BIB_147C78DD33B3]
 
Systems biology to battle vascular disease.
Dominiczak A.F., Herget-Rosenthal S., Delles C., Fliser D., Fournier I., Graber A., Girolami M., Holmes E., Lang F., Molina F. et al., 2010. Nephrology, Dialysis, Transplantation, 25 (4) pp. 1019-1022.
[DOI][WoS][Pmid][serval:BIB_4869BE2AC0C6]
The Arabidopsis PHYTOCHROME KINASE SUBSTRATE2 protein is a phototropin signaling element that regulates leaf flattening and leaf positioning.
de Carbonnel M., Davis P., Roelfsema M.R., Inoue S., Schepens I., Lariguet P., Geisler M., Shimazaki K., Hangarter R., Fankhauser C., 2010. Plant Physiology, 152 (3) pp. 1391-1405. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_F777C7E061E2]
 
The effect of translocation-induced nuclear reorganization on gene expression.
Harewood L., Schütz F., Boyle S., Perry P., Delorenzi M., Bickmore W.A., Reymond A., 2010. Genome Research, 20 (5) pp. 554-564. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_38609FB2657D]
 
The emergence of new genes on the young therian X.
Potrzebowski L., Vinckenbosch N., Kaessmann H., 2010. Trends in Genetics, 26 (1) pp. 1-4. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_3CE20BAB7471]
The Gene Ontology in 2010: extensions and refinements.
Gene Ontology Consortium, 2010. Nucleic Acids Research, 38 (Database issue) pp. D331-D335.
[URN][DOI][WoS][Pmid][serval:BIB_C3C5174BCA6C]
The nuclear receptor DHR3 modulates dS6 kinase-dependent growth in Drosophila.
Montagne J., Lecerf C., Parvy J.P., Bennion J.M., Radimerski T., Ruhf M.L., Zilbermann F., Vouilloz N., Stocker H., Hafen E. et al., 2010. PLoS Genetics, 6 (5) pp. e1000937.
[URN][DOI][WoS][Pmid][serval:BIB_3A593FA702F4]
The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms.
Feige J.N., Gerber A., Casals-Casas C., Yang Q., Winkler C., Bedu E., Bueno M., Gelman L., Auwerx J., Gonzalez F.J. et al., 2010. Environmental Health Perspectives, 118 (2) pp. 234-241. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_15084BA0F852]
The PPARbeta/delta agonist GW0742 relaxes pulmonary vessels and limits right heart hypertrophy in rats with hypoxia-induced pulmonary hypertension.
Harrington L.S., Moreno L., Reed A., Wort S.J., Desvergne B., Garland C., Zhao L., Mitchell J.A., 2010. PLoS One, 5 (3) pp. e9526. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_8343946CB81F]
The role of transcription factories-mediated interchromosomal contacts in the organization of nuclear architecture.
Dorier J., Stasiak A., 2010. Nucleic Acids Research, 38 (21) pp. 7410-7421. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_5D2209110663]
The Universal Protein Resource (UniProt) in 2010.
UniProt Consortium, 2010. Nucleic Acids Research, 38 (Database issue) pp. D142-D148.
[URN][DOI][WoS][Pmid][serval:BIB_41A174DE1892]
 
Thioredoxin-interacting protein links oxidative stress to inflammasome activation.
Zhou R., Tardivel A., Thorens B., Choi I., Tschopp J., 2010. Nature Immunology, 11 (2) pp. 136-140. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_E05AA44F8170]
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
Elks C.E., Perry J.R., Sulem P., Chasman D.I., Franceschini N., He C., Lunetta K.L., Visser J.A., Byrne E.M., Cousminer D.L. et al., 2010. Nature Genetics, 42 (12) pp. 1077-1085. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_1764CFBA5790]
 
Transcriptional profiling reveals divergent roles of PPARalpha and PPARbeta/delta in regulation of gene expression in mouse liver.
Sanderson L.M., Boekschoten M.V., Desvergne B., Müller M., Kersten S., 2010. Physiological Genomics, 41 (1) pp. 42-52.
[DOI][WoS][Pmid][serval:BIB_1A59CC9FB332]
 
Uric acid transport and disease.
So A., Thorens B., 2010. Journal of Clinical Investigation, 120 (6) pp. 1791-1799.
[DOI][WoS][Pmid][serval:BIB_74F7918F742F]
2009
 
Dépistage du cancer de la prostate: actualité [Prostate cancer screening: an update]
Tawadros T., Doerfler A., Treuthardt C., Praz V., Levi F., Zouhair A., Berthold D., Bauer J., Iselin C., Jichlinski P., 2009/12/02. Revue medicale suisse, 5 (228) pp. 2438-2441. Peer-reviewed.
[Pmid][serval:BIB_11E9631D48D2]
 
PPAR-mediated activity of phthalates: A link to the obesity epidemic?
Desvergne B., Feige J.N., Casals-Casas C., 2009/05. Molecular and cellular endocrinology, 304 (1-2) pp. 43-48. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_4D65DAFD003E]
A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.
Demers A., Caron V., Rodrigue-Way A., Wahli W., Ong H., Tremblay A., 2009. Plos One, 4 (11) pp. e7728. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_B86D5A1DB82A]
 
A novel method of dynamic culture surface expansion improves mesenchymal stem cell proliferation and phenotype.
Majd H., Wipff P.J., Buscemi L., Bueno M., Vonwil D., Quinn T.M., Hinz B., 2009. Stem Cells, 27 (1) pp. 200-209.
[DOI][WoS][Pmid][serval:BIB_B20F6CE182AD]
A partial ordering of knots and links through diagrammatic unknotting
Diao Y., Ernst C., Stasiak A., 2009. Journal of Knot Theory and its Ramifications, 18 (4) pp. 505-522. Peer-reviewed.
[URN][DOI][WoS][serval:BIB_E9F6D0EED72F]
 
Activation of PPAR delta Regulates Ywhae (Encoding 14-3-3 epsilon Protein), a Gene Required for Ventricular Morphogenesis
Brunelli L., Cieslik K.A., Michalik L., Wahli W., Yost H.J., 2009. pp. E15-E15 dans Basic Cardiovascular Sciences Conference 2009, Circulation Research. Peer-reviewed.
[WoS][serval:BIB_995C8F04E541]
 
An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.
Olma M.H., Roy M., Le Bihan T., Sumara I., Maerki S., Larsen B., Quadroni M., Peter M., Tyers M., Pintard L., 2009. Journal of cell science, 122 (Pt 7) pp. 1035-1044. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BB0B11AC8604]
AssociationViewer: a scalable and integrated software tool for visualization of large-scale variation data in genomic context.
Martin O., Valsesia A., Telenti A., Xenarios I., Stevenson B.J., 2009. Bioinformatics, 25 (5) pp. 662-663.
[URN][DOI][WoS][Pmid][serval:BIB_89D969C4038A]
 
Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets.
Lohmann C., Schäfer N., von Lukowicz T., Sokrates Stein M.A., Borén J., Rütti S., Wahli W., Donath M.Y., Lüscher T.F., Matter C.M., 2009. Atherosclerosis, 207 (2) pp. 360-367. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1AFA54F417D1]
Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles.
Demurtas D., Amzallag A., Rawdon E.J., Maddocks J.H., Dubochet J., Stasiak A., 2009. Nucleic Acids Research, 37 (9) pp. 2882-2893. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_BC7848C64B2B]
cGMP-dependent protein kinase type I is implicated in the regulation of the timing and quality of sleep and wakefulness.
Langmesser S., Franken P., Feil S., Emmenegger Y., Albrecht U., Feil R., 2009. PloS one, 4 (1) pp. e4238.
[URN][DOI][WoS][Pmid][serval:BIB_DD0A8710F767]
 
Circadian clock genes and sleep homeostasis.
Franken P., Dijk D.J., 2009. European Journal of Neuroscience, 29 (9) pp. 1820-1829. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_58B7DEC14205]
 
Comparative genomic and phylogeographic analysis of Mycobacterium leprae.
Monot M., Honoré N., Garnier T., Zidane N., Sherafi D., Paniz-Mondolfi A., Matsuoka M., Taylor G.M., Donoghue H.D., Bouwman A. et al., 2009. Nature Genetics, 41 (12) pp. 1282-1289. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_BDCCC23F57D7]
Comprehensive analysis of Arabidopsis expression level polymorphisms with simple inheritance.
Plantegenet S., Weber J., Goldstein D.R., Zeller G., Nussbaumer C., Thomas J., Weigel D., Harshman K., Hardtke C.S., 2009. Molecular Systems Biology, 5 p. 242. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_4FFA2CBD1C42]
Copy number variants, diseases and gene expression.
Henrichsen C.N., Chaignat E., Reymond A., 2009. Human Molecular Genetics, 18 (R1) pp. R1-R8. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_DA076768B7BD]
 
DNA-DNA interactions in bacteriophage capsids are responsible for the observed DNA knotting.
Marenduzzo D., Orlandini E., Stasiak A., Sumners de W, Tubiana L., Micheletti C., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (52) pp. 22269-22274. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_89D4E77514A2]
 
Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation.
Buchon N., Broderick N.A., Poidevin M., Pradervand S., Lemaitre B., 2009. Cell Host and Microbe, 5 (2) pp. 200-211.
[DOI][WoS][Pmid][serval:BIB_7D17827D6935]
 
E2F1 mediates DNA damage and apoptosis through HCF-1 and the MLL family of histone methyltransferases.
Tyagi S., Herr W., 2009. EMBO Journal, 28 (20) pp. 3185-3195. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_23FC0FE74C64]
 
Effect of knotting on polymer shapes and their enveloping ellipsoids.
Millett K.C., Plunkett P., Piatek M., Rawdon E.J., Stasiak A., 2009. Journal of Chemical Physics, 130 (16) p. 165104. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_EF24549906CD]
 
ENFIN--A European network for integrative systems biology.
Kahlem P., Clegg A., Reisinger F., Xenarios I., Hermjakob H., Orengo C., Birney E., 2009. Comptes Rendus Biologies, 332 (11) pp. 1050-1058.
[DOI][WoS][Pmid][serval:BIB_FEEF11BD9FD8]
 
Eppendorf winner. Evolution and revolution in odor detection.
Benton R., 2009. Science, 326 (5951) pp. 382-383.
[DOI][WoS][Pmid][serval:BIB_6C505030EEE8]
 
Evolutionary origin and functions of retrogene introns.
Fablet M., Bueno M., Potrzebowski L., Kaessmann H., 2009. Molecular Biology and Evolution, 26 (9) pp. 2147-2156. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_617FE6260226]
Expression of the NH(2)-terminal fragment of RasGAP in pancreatic beta-cells increases their resistance to stresses and protects mice from diabetes.
Yang J.Y., Walicki J., Jaccard E., Dubuis G., Bulat N., Hornung J.P., Thorens B., Widmann C., 2009. Diabetes, 58 (11) pp. 2596-2606. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_9B124E90768D]
 
Fatty acid synthesis and PPARalpha hand in hand.
Rotman N., Wahli W., 2009. Chemistry and Biology, 16 (8) pp. 801-802.
[DOI][WoS][Pmid][serval:BIB_602EA975B70E]
 
Gene expression profiling in the human pathogenic dermatophyte Trichophyton rubrum during growth on proteins.
Zaugg C., Monod M., Weber J., Harshman K., Pradervand S., Thomas J., Bueno M., Giddey K., Staib P., 2009. Eukaryotic Cell, 8 (2) pp. 241-250. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_76E5A40AB1D6]
 
Genetic approaches to the problem of sleep
Gregory A.M., Franken P., 2009. pp. 41-61 dans Frank M.G. (eds.) Current Advances in Sleep Biology chap. 4, Nova Science Publishers.
[serval:BIB_C9228DFDA102]
 
Genetic aspects of normal and disturbed sleep.
Tafti M., 2009. Sleep Medicine, 10 Suppl 1 pp. S17-S21.
[DOI][WoS][Pmid][serval:BIB_7D8414C8EAEC]
 
Genetics. More than just a copy.
Kaessmann H., 2009. Science, 325 (5943) pp. 958-959.
[DOI][WoS][Pmid][serval:BIB_2EE4E75CBEE3]
Geometric control of the cell cycle.
Martin S.G., 2009. Cell Cycle, 8 (22) pp. 3643-3647. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_918B2853B9FA]
 
GLP-1 protects beta-cells against apoptosis by enhancing the activity of an IGF-2/IGF-1 receptor autocrine loop
Cornu M, Thorens B, 2009. Islets, 1 (3) pp. 280-282. Peer-reviewed.
[DOI][WoS][serval:BIB_3E5801696B4F]
Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop.
Cornu M., Yang J.Y., Jaccard E., Poussin C., Widmann C., Thorens B., 2009. Diabetes, 58 (8) pp. 1816-1825. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_67E118FEC494]
 
Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth.
Buhren B.A., Gasis M., Thorens B., Müller H.W., Bosse F., 2009. Journal of Neuroscience Research, 87 (8) pp. 1858-1870.
[DOI][WoS][Pmid][serval:BIB_4A9CD880C6FC]
 
Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy.
Preitner F., Bonny O., Laverrière A., Rotman S., Firsov D., Da Costa A., Metref S., Thorens B., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (36) pp. 15501-15506.
[DOI][WoS][Pmid][serval:BIB_1EC881C9D168]
Higher plants use LOV to perceive blue light.
Demarsy E., Fankhauser C., 2009. Current Opinion in Plant Biology, 12 (1) pp. 69-74. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_D9AB07A52F0D]
 
How to keep the brain awake? The complex molecular pharmacogenetics of wake promotion.
Hasan S., Pradervand S., Ahnaou A., Drinkenburg W., Tafti M., Franken P., 2009. Neuropsychopharmacology, 34 (7) pp. 1625-1640. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_400923123B66]
Identifying protein-coding genes in genomic sequences.
Harrow J., Nagy A., Reymond A., Alioto T., Patthy L., Antonarakis S.E., Guigó R., 2009. Genome biology, 10 (1) p. 201. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_69A902D4D75D]
 
Impact of normalization on miRNA microarray expression profiling.
Pradervand S., Weber J., Thomas J., Bueno M., Wirapati P., Lefort K., Dotto G.P., Harshman K., 2009. RNA, 15 (3) pp. 493-501. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_2FCA2A7EA859]
Inhibition of the shade avoidance response by formation of non-DNA binding bHLH heterodimers.
Hornitschek P., Lorrain S., Zoete V., Michielin O., Fankhauser C., 2009. EMBO journal, 28 (24) pp. 3893-3902.
[URN][DOI][WoS][Pmid][serval:BIB_F6BFB65AF903]
 
Inhibitory effect of DNA supercoiling on DNA knotting
Dorier J., Burnier Y., Stasiak A., 2009. Bussei Kenkyu, 92 (1) pp. 84-88. Peer-reviewed.
[serval:BIB_B3C1D95595C0]
Interplay of DNA supercoiling and catenation during the segregation of sister duplexes.
Martínez-Robles M.L., Witz G., Hernández P., Schvartzman J.B., Stasiak A., Krimer D.B., 2009. Nucleic Acids Research, 37 (15) pp. 5126-5137. Peer-reviewed.
[URN][DOI][WoS][Pmid][serval:BIB_C26EB08DD54C]
 
Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells.
Pétremand J., Bulat N., Butty A.C., Poussin C., Rütti S., Au K., Ghosh S., Mooser V., Thorens B., Yang J.Y. et al., 2009. Molecular Endocrinology, 23 (10) pp. 1572-1586. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A437670219D3]
 
La surveillance active dans la prise en charge du cancer de la prostate précoce. [Active surveillance for early-stage prostate cancer]
Jichlinski P., Berthold D. R., Zouhair A., Griesser A. C., Meuwly J. Y., Prior J. O., Lhermitte B., Doerfler A., Treuthardt C., Praz V. et al., 2009. Revue médicale suisse, 5 (228) pp. 2442-4, 2446-7.
[Pmid][serval:BIB_66220A2D6BE9]
 
LKB1 regulates polarity remodeling and adherens junction formation in the Drosophila eye.
Amin N., Khan A., St Johnston D., Tomlinson I., Martin S., Brenman J., McNeill H., 2009. Proceedings of the National Academy of Sciences of the United States of America, 106 (22) pp. 8941-8946. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_A90FC22483A3]
Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice.
Tsai J.W., Hannibal J., Hagiwara G., Colas D., Ruppert E., Ruby N.F., Heller H.C., Franken P., Bourgin P., 2009. PLoS biology, 7 (6) pp. e1000125.
[URN][DOI][WoS][Pmid][serval:BIB_2C0C582502C4]
 
Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice.
Isken F., Weickert M.O., Tschöp M.H., Nogueiras R., Möhlig M., Abdelrahman A., Klaus S., Thorens B., Pfeiffer A.F., 2009. Diabetologia, 52 (10) pp. 2159-2168.
[DOI][WoS][Pmid][serval:BIB_28F7A3AC9581]
 
Metabolic labeling and protein linearization technology allow the study of proteins secreted by cultured cells in serum-containing media.
Colzani M., Waridel P., Laurent J., Faes E., Rüegg C., Quadroni M., 2009. Journal of Proteome research, 8 (10) pp. 4779-4788.
[DOI][WoS][Pmid][serval:BIB_7DDA894596D3]
 
Microtubule-dependent cell morphogenesis in the fission yeast.
Martin S.G., 2009. Trends in Cell Biology, 19 (9) pp. 447-454. Peer-reviewed.
[DOI][WoS][Pmid][serval:BIB_1236A66A0238]
MIMAS 3.0 is a Multiomics Information Management and Annotation System.
Gattiker A., Hermida L., Liechti R., Xenarios I., Collin O., Rougemont J., Primig M., 2009. BMC Bioinformatics, 10 p. 151.
[URN][DOI][WoS][Pmid][serval:BIB_2455DAB29335]
Modeling stochasticity and robustness in gene regulatory networks.
Garg A., Mohanram K., Di Cara A., De Micheli G., Xenarios I., 2009. Bioinformatics, 25 (12) pp. i101-i109.
[URN][DOI][WoS][Pmid][serval:BIB_3C1AE80B8836]
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