Paola Bezzi

Publications | Mémoires et thèses

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65 publications

2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2002 | 2001 | 1999 | 1998 | 1997 | 1996 | 1995 |
Metabolic dynamics in astrocytes and microglia during post-natal development and their implications for autism spectrum disorders.
Cantando I., Centofanti C., D'Alessandro G., Limatola C., Bezzi P., 2024. Frontiers in cellular neuroscience, 18 p. 1354259. Peer-reviewed.
Microglia at the Tripartite Synapse during Postnatal Development: Implications for Autism Spectrum Disorders and Schizophrenia.
Ferrucci L., Cantando I., Cordella F., Di Angelantonio S., Ragozzino D., Bezzi P., 2023/12/13. Cells, 12 (24) p. 2827. Peer-reviewed.
Unlocking Neural Function with 3D In Vitro Models: A Technical Review of Self-Assembled, Guided, and Bioprinted Brain Organoids and Their Applications in the Study of Neurodevelopmental and Neurodegenerative Disorders.
D'Antoni C., Mautone L., Sanchini C., Tondo L., Grassmann G., Cidonio G., Bezzi P., Cordella F., Di Angelantonio S., 2023/06/28. International journal of molecular sciences, 24 (13). Peer-reviewed.
Disruption of Astrocyte-Dependent Dopamine Control in the Developing Medial Prefrontal Cortex Leads to Excessive Grooming in Mice.
Petrelli F., Zehnder T., Laugeray A., Mondoloni S., Calì C., Pucci L., Molinero Perez A., Bondiolotti B.M., De Oliveira Figueiredo E., Dallerac G. et al., 2023/06/01. Biological psychiatry, 93 (11) pp. 966-975. Peer-reviewed.
Editorial: Glial heterogeneity: impact on neuronal function and dysfunction.
Bezzi P., Magnaghi V., Paolicelli R.C., Hornung J.P., 2023. Frontiers in neuroanatomy, 17 p. 1249919. Peer-reviewed.
Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3.
Ratano P., Cocozza G., Pinchera C., Busdraghi L.M., Cantando I., Martinello K., Scioli M., Rosito M., Bezzi P., Fucile S. et al., 2023. Frontiers in molecular neuroscience, 16 p. 1333745. Peer-reviewed.
Human iPSC-Derived Cortical Neurons Display Homeostatic Plasticity.
Cordella F., Ferrucci L., D'Antoni C., Ghirga S., Brighi C., Soloperto A., Gigante Y., Ragozzino D., Bezzi P., Di Angelantonio S., 2022/11/14. Life, 12 (11) p. 1884. Peer-reviewed.
Emerging evidence for astrocyte dysfunction in schizophrenia.
de Oliveira Figueiredo E.C., Calì C., Petrelli F., Bezzi P., 2022/09. Glia, 70 (9) pp. 1585-1604. Peer-reviewed.
Synaptic Plasticity Dysfunctions in the Pathophysiology of 22q11 Deletion Syndrome: Is There a Role for Astrocytes?
de Oliveira Figueiredo E.C., Bondiolotti B.M., Laugeray A., Bezzi P., 2022/04/16. International journal of molecular sciences, 23 (8) p. 4412. Peer-reviewed.
Tweaking neural organoids to model human reactive astrocytes.
Bezzi P., 2022/04/04. The Journal of cell biology, 221 (4) pp. e202202026. Peer-reviewed.
Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation.
Zehnder T., Petrelli F., Romanos J., De Oliveira Figueiredo E.C., Lewis T.L., Déglon N., Polleux F., Santello M., Bezzi P., 2021/04/13. Cell reports, 35 (2) p. 108952. Peer-reviewed.
Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease
Richetin Kevin, Steullet Pascal, Pachoud Mathieu, Perbet Romain, Parietti Enea, Maheswaran Mathischan, Eddarkaoui Sabiha, Bégard Séverine, Pythoud Catherine, Rey Maria et al., 2020/12. Nature Neuroscience, 23 (12) pp. 1567-1579. Peer-reviewed.
A New Pathway Promotes Adaptation of Human Glioblastoma Cells to Glucose Starvation.
Azzalin A., Brambilla F., Arbustini E., Basello K., Speciani A., Mauri P., Bezzi P., Magrassi L., 2020/05/18. Cells, 9 (5) p. 1249. Peer-reviewed.
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.
Petrelli F., Dallérac G., Pucci L., Calì C., Zehnder T., Sultan S., Lecca S., Chicca A., Ivanov A., Asensio C.S. et al., 2020/04. Molecular psychiatry, 25 (4) pp. 732-749. Peer-reviewed.
Spatio-temporal overview of neuroinflammation in an experimental mouse stroke model.
Buscemi L., Price M., Bezzi P., Hirt L., 2019/01/24. Scientific reports, 9 (1) p. 507. Peer-reviewed.
Insights into the release mechanism of astrocytic glutamate evoking in neurons NMDA receptor-mediated slow depolarizing inward currents.
Gómez-Gonzalo M., Zehnder T., Requie L.M., Bezzi P., Carmignoto G., 2018/10. Glia, 66 (10) pp. 2188-2199. Peer-reviewed.
mGlu5-mediated signalling in developing astrocyte and the pathogenesis of autism spectrum disorders.
Petrelli F., Bezzi P., 2018/02. Current opinion in neurobiology, 48 pp. 139-145. Peer-reviewed.
Homer1 Scaffold Proteins Govern Ca2+ Dynamics in Normal and Reactive Astrocytes.
Buscemi L., Ginet V., Lopatar J., Montana V., Pucci L., Spagnuolo P., Zehnder T., Grubišic V., Truttman A., Sala C. et al., 2017/03/01. Cerebral cortex (New York, N.Y. : 1991), 27 (3) pp. 2365-2384. Peer-reviewed.
SHANK3 controls maturation of social reward circuits in the VTA.
Bariselli S., Tzanoulinou S., Glangetas C., Prévost-Solié C., Pucci L., Viguié J., Bezzi P., O'Connor E.C., Georges F., Lüscher C. et al., 2016/07. Nature neuroscience, 19 (7) pp. 926-934. Peer-reviewed.
Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders.
Petrelli F., Pucci L., Bezzi P., 2016. Frontiers In Cellular Neuroscience, 10 p. 21. Peer-reviewed.
Novel insights into gliotransmitters.
Petrelli F., Bezzi P., 2016. Current Opinion In Pharmacology, 26 pp. 138-145. Peer-reviewed.
Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes.
Sultan S., Li L., Moss J., Petrelli F., Cassé F., Gebara E., Lopatar J., Pfrieger F.W., Bezzi P., Bischofberger J. et al., 2015. Neuron, 88 (5) pp. 957-972. Peer-reviewed.
Analysis of synaptic-like microvesicle exocytosis of B-cells using a live imaging technique.
Bergeron A., Pucci L., Bezzi P., Regazzi R., 2014. Plos One, 9 (2) pp. e87758. Peer-reviewed.
G-protein coupled receptor-evoked glutamate exocytosis from astrocytes: role of prostaglandins.
Cali C., Lopatar J., Petrelli F., Pucci L., Bezzi P., 2014. Neural Plasticity, 2014 p. 254574.
Identification and staining of distinct populations of secretory organelles in astrocytes.
Bezzi P., Volterra A., 2014. Cold Spring Harbor Protocols, 2014 (5) pp. 532-536.
Imaging exocytosis and recycling of synaptic-like microvesicles in astrocytes.
Bezzi P., Volterra A., 2014. Cold Spring Harbor Protocols, 2014 (5) pp. 537-543.
Understanding the multifaceted role of inflammatory mediators in ischemic stroke.
Amantea D., Tassorelli C., Petrelli F., Certo M., Bezzi P., Micieli G., Corasaniti M.T., Bagetta G., 2014. Current Medicinal Chemistry, 21 (18) pp. 2098-2117. Peer-reviewed.
The GTPase Rab37 Participates in the Control of Insulin Exocytosis.
Ljubicic S., Bezzi P., Brajkovic S., Nesca V., Guay C., Ohbayashi N., Fukuda M., Abderrhamani A., Regazzi R., 2013. Plos One, 8 (6) pp. e68255. Peer-reviewed.
Adenosine A2B receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity.
Moidunny S., Vinet J., Wesseling E., Bijzet J., Shieh C.H., van Ijzendoorn S.C., Bezzi P., Boddeke H.W., Biber K., 2012. Journal of Neuroinflammation, 9 p. 198. Peer-reviewed.
Gliotransmission and the tripartite synapse.
Santello M., Calì C., Bezzi P., 2012. pp. 307-331 dans Kreutz M.R., Sla C. (eds.) Synaptic plasticity : dynamics, development and disease chap. 14, Springer.
The BH4 domain of Bcl-X(L) rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals.
Martorana F., Brambilla L., Valori C.F., Bergamaschi C., Roncoroni C., Aronica E., Volterra A., Bezzi P., Rossi D., 2012. Human Molecular Genetics, 21 (4) pp. 826-840. Peer-reviewed.
Astrocyte dense-core vesicle gliosecretion is governed by rest/nrsf
Prada J., Marchaland J., Podini P., Magrassi L., D'Alessandro R., Bezzi P., Meldolesi J., 2011. pp. S55 dans 10th European meeting on Glial Cells in Health and Disease, GLIA.
Astrocytes: powering memory.
Bezzi P., Volterra A., 2011. Cell, 144 (5) pp. 644-645.
Glioprotective impact of cell-permeable peptides in preclinical models of amyotrophic lateral sclerosis
Rossi D., Martorana F., Valori C., Roncoroni C., Bergamaschi C., Volterra A., Bezzi P., Brambilla L., 2011. pp. S81 dans 10th European meeting on Glial Cells in Health and Disease, GLIA.
Rest/nrsf governs the expression of dense-core vesicle gliosecretion in astrocytes
Bezzi P., Prada J., Marchaland J., Podini P., Magrassi L., D'Alessandro R., Meldolesi J., 2011. pp. S33 dans 10th European meeting on Glial Cells in Health and Disease, GLIA.
REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes.
Prada I., Marchaland J., Podini P., Magrassi L., D'Alessandro R., Bezzi P., Meldolesi J., 2011. Journal of Cell Biology, 193 (3) pp. 537-549. Peer-reviewed.
Role of homer 1 proteins in the calcium signaling pathway(s) underlying exo-endocytosis processes of glutamatergic slmvs in astrocytes
Cali C., Marchaland J., Ginet L., Hirt L., Truttmann A.C., Puyal J., Bezzi P., 2011. pp. S127 dans 10th European Meeting on Glial Cells in Health and Disease, GLIA. Peer-reviewed.
TNFα controls glutamatergic gliotransmission in the hippocampal dentate gyrus.
Santello M., Bezzi P., Volterra A., 2011. Neuron, 69 (5) pp. 988-1001.
CXCR4-mediated glutamate exocytosis from astrocytes.
Calì C., Bezzi P., 2010/07. Journal of Neuroimmunology, 224 (1-2) pp. 13-21. Peer-reviewed.
Calcium Microdomains Control Exo-Endocytosis of Synaptic-Like Microvesicles in Astrocytes
Marchaland J., Cali C., Voglmaier S.M., Li H., Regazzi R., Edwards R.H., Bezzi P., 2009. p. 45 dans 9th European Meeting on Glial Cells in Health and Disease, Glia. Peer-reviewed.
Functional Microdomains Control Glutamate Exocytosis from Astrocytes
Bezzi P., Marchaland J., Cali C., Spagnuolo P., Gremion J., Voglmaier S., Sala C., Edwards R. H., 2009. p. 23 dans 9th European Meeting on Glial Cells in Health and Disease, Glia. Peer-reviewed.
Regulated exocytosis from astrocytes physiological and pathological related aspects.
Calì C., Marchaland J., Spagnuolo P., Gremion J., Bezzi P., 2009. International review of neurobiology, 85 pp. 261-93. Peer-reviewed.
The GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells.
Ljubicic S., Bezzi P., Vitale N., Regazzi R., 2009. PloS one, 4 (11) pp. e7770. Peer-reviewed.
SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: Imaging analysis at the single-vesicle level with TIRF microscopy
Cali C., Marchaland J., Regazzi R., Bezzi P., 2008/07. Journal of Neuroimmunology, 198 (1-2) pp. 82-91. Peer-reviewed.
Fast subplasma membrane Ca2+ transients control exo-endocytosis of synaptic-like microvesicles in astrocytes
Marchaland J., Cali C., Voglmaier S. M., Li H., Regazzi R., Edwards R. H., Bezzi P., 2008. Journal of Neuroscience, 28 (37) pp. 9122-9132. Peer-reviewed.
Glutamate exocytosis from astrocytes controls synaptic strength.
Jourdain P., Bergersen L.H., Bhaukaurally K., Bezzi P., Santello M., Domercq M., Matute C., Tonello F., Gundersen V., Volterra A., 2007. Nature Neuroscience, 10 (3) pp. 331-339.
P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins.
Domercq M., Brambilla L., Pilati E., Marchaland J., Volterra A., Bezzi P., 2006. Journal of Biological Chemistry, 281 (41) pp. 30684-30696. Peer-reviewed.
Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis.
Cheviet S., Bezzi P., Ivarsson R., Renström E., Viertl D., Kasas S., Catsicas S., Regazzi R., 2006. Journal of Cell Science, 119 (Pt 14) pp. 2912-2920.
Defective tumor necrosis factor-alpha-dependent control of astrocyte glutamate release in a transgenic mouse model of Alzheimer disease.
Rossi D., Brambilla L., Valori C.F., Crugnola A., Giaccone G., Capobianco R., Mangieri M., Kingston A.E., Bloc A., Bezzi P. et al., 2005. Journal of Biological Chemistry, 280 (51) pp. 42088-42096. Peer-reviewed.
Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate.
Bezzi P., Gundersen V., Galbete J.L., Seifert G., Steinhäuser C., Pilati E., Volterra A., 2004. Nature Neuroscience, 7 (6) pp. 613-620.
Release of transmitters from glial cells
Volterra A., Bezzi P., 2002. pp. 164-182 dans Volterra A., Magistretti P., Haydon P.G. (eds.) The tripartite synapse: glia in synaptic transmission, Oxford University Press.
A neuron-glia signalling network in the active brain.
Bezzi P., Volterra A., 2001. Current Opinion in Neurobiology, 11 (3) pp. 387-394.
CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity.
Bezzi P., Domercq M., Brambilla L., Galli R., Schols D., De Clercq E., Vescovi A., Bagetta G., Kollias G., Meldolesi J. et al., 2001. Nature Neuroscience, 4 (7) pp. 702-710.
Neuron-astrocyte cross-talk during synaptic transmission: physiological and neuropathological implications.
Bezzi P., Domercq M., Vesce S., Volterra A., 2001. Progress in Brain Research, 132 pp. 255-265.
Synaptic transmission with the glia.
Vesce S., Bezzi P., Volterra A., 2001. News in Physiological Sciences, 16 pp. 178-184. Peer-reviewed.
Astrocytes as active participants of glutamatergic function and regulators of its homeostasis.
Bezzi P., Vesce S., Panzarasa P., Volterra A., 1999. Advances in Experimental Medicine and Biology, 468 pp. 69-80.
Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes.
Civenni G., Bezzi P., Trotti D., Volterra A., Racagni G., 1999. European Journal of Pharmacology, 370 (2) pp. 161-167.
The active role of astrocytes in synaptic transmission.
Vesce S., Bezzi P., Volterra A., 1999. Cellular and Molecular Life Sciences, 56 (11-12) pp. 991-1000.
The highly integrated dialogue between neurons and astrocytes in brain function.
Vesce S., Bezzi P., Volterra A., 1999. Science Progress, 82 ( Pt 3) pp. 251-270.
Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.
Bezzi P., Carmignoto G., Pasti L., Vesce S., Rossi D., Rizzini B.L., Pozzan T., Volterra A., 1998. Nature, 391 (6664) pp. 281-285.
HIV-1 gp120 glycoprotein affects the astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid.
Vesce S., Bezzi P., Rossi D., Meldolesi J., Volterra A., 1997. FEBS Letters, 411 (1) pp. 107-109.
Glutamate transporters: molecular mechanisms of functional alteration and role in the development of excitotoxic neuronal injury
Trotti D, Danbolt NC, Lodi Rizzini B, Bezzi P, Rossi D, Racagni G, Volterra A, 1996. pp. 33-36 dans Fiskum G. (eds.) Neurodegenerative diseases : molecular and cellular mechanisms and therapeutic advances chap. 5, Plenum Press.
Molecular mechanisms of functional lateration of glutamate transporters and relevance to neuropathology
Trotti D, Rossi D, Lodi Rizzini B, Bezzi P, Danbolt NC, Racagni G, Volterra A, 1996. pp. 46-48 dans Shibuya T. (eds.) Preclinical and clinical strategies for the treatment of neurodegenerative, cerebrovascular and mental disorders, Karger.
The competitive transport inhibitor L-trans-pyrrolidine-2, 4-dicarboxylate triggers excitotoxicity in rat cortical neuron-astrocyte co-cultures via glutamate release rather than uptake inhibition.
Volterra A., Bezzi P., Rizzini B.L., Trotti D., Ullensvang K., Danbolt N.C., Racagni G., 1996. European Journal of Neuroscience, 8 (9) pp. 2019-2028.
[Ca2+] modulates the ratio between cycloxygenase and lipoxygenase metabolism of arachidonic acid in homogenates of hippocampal astroglial cultures.
Volterra A., Trotti D., Bezzi P., Civenni G., Racagni G., 1995. Neuroscience Letters, 183 (3) pp. 160-163.
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