Département d'immunobiologie

Equipe principale
Publications | Mémoires et thèses

La recherche avancée est accessible via Serval

Les publications peuvent être gérées en accédant à Serval via MyUnil


2189 publications

... | 2020 | 2019 | 2018 | 2017 | ...
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell
Eran Mick, Denis V Titov, Owen S Skinner, Rohit Sharma, Alexis A Jourdain, Vamsi K Mootha, 2020/05/28. eLife. Peer-reviewed.
 
Differentially regulated promoters for antigen expression in Salmonella vaccine strains.
Stojanov M., Besançon H., Snäkä T., Nardelli-Haefliger D., Curtiss R., Baud D., 2020/05/27. Vaccine, 38 (26) pp. 4154-4161. Peer-reviewed.
The Role of TNFR2 and DR3 in the In Vivo Expansion of Tregs in T Cell Depleting Transplantation Regimens.
Rodriguez-Barbosa J.I., Schneider P., Graca L., Bühler L., Perez-Simon J.A., Del Rio M.L., 2020/05/09. International journal of molecular sciences, 21 (9) p. 3347. Peer-reviewed.
 
Viral Double-Stranded RNA Detection by DNase I and Nuclease S1 digestions in Leishmania parasites.
Isorce N., Fasel N., 2020/05/05. Bio-protocol, 10 (9) pp. e3598. Peer-reviewed.
 
M2-like, dermal macrophages are maintained via IL-4/CCL24-mediated cooperative interaction with eosinophils in cutaneous leishmaniasis.
Lee S.H., Chaves M.M., Kamenyeva O., Gazzinelli-Guimaraes P.H., Kang B., Pessenda G., Passelli K., Tacchini-Cottier F., Kabat J., Jacobsen E.A. et al., 2020/04/10. Science immunology, 5 (46) pp. eaaz4415. Peer-reviewed.
SPACE I - 2019 – Council of Europe Annual Penal Statistics: Prison populations
Aebi Marcelo F., Tiago Mélanie M., 2020/04/05., Council of Europe.
Out of Africa: The origins of the protozoan blood parasites of the Trypanosoma cruzi clade found in bats from Africa.
Clément L., Dietrich M., Markotter W., Fasel N.J., Monadjem A., López-Baucells A., Scaravelli D., Théou P., Pigeault R., Ruedi M. et al., 2020/04. Molecular phylogenetics and evolution, 145 p. 106705. Peer-reviewed.
 
Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways.
Muri J., Feng Q., Wolleb H., Shamshiev A., Ebner C., Tortola L., Broz P., Carreira E.M., Kopf M., 2020/03/31. Cell reports, 30 (13) pp. 4399-4417.e7. Peer-reviewed.
 
Novel Autoantibody Signatures in Sera of Patients with Pancreatic Cancer, Chronic Pancreatitis and Autoimmune Pancreatitis: A Protein Microarray Profiling Approach
Ghassem-Zadeh Sahar, Hufnagel Katrin, Bauer Andrea, Frossard Jean-Louis, Yoshida Masaru, Kutsumi Hiromu, Acha-Orbea Hans, Neulinger-Muñoz Matthias, Vey Johannes, Eckert Christoph et al., 2020/03/31. International Journal of Molecular Sciences, 21 (7) p. 2403. Peer-reviewed.
Novel strategies for expansion of tooth epithelial stem cells and ameloblast generation.
Binder M., Biggs L.C., Kronenberg M.S., Schneider P., Thesleff I., Balic A., 2020/03/18. Scientific reports, 10 (1) p. 4963. Peer-reviewed.
 
Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases.
Minina E.A., Staal J., Alvarez V.E., Berges J.A., Berman-Frank I., Beyaert R., Bidle K.D., Bornancin F., Casanova M., Cazzulo J.J. et al., 2020/03/05. Molecular cell, 77 (5) pp. 927-929. Peer-reviewed.
 
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.
Ragusa S., Prat-Luri B., González-Loyola A., Nassiri S., Squadrito M.L., Guichard A., Cavin S., Gjorevski N., Barras D., Marra G. et al., 2020/03/02. The Journal of clinical investigation, 130 (3) pp. 1199-1216. Peer-reviewed.
Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis.
Jarosz-Griffiths H.H., Scambler T., Wong C.H., Lara-Reyna S., Holbrook J., Martinon F., Savic S., Whitaker P., Etherington C., Spoletini G. et al., 2020/03/02. eLife, 9 pp. e54556. Peer-reviewed.
Inflammasomes contributing to inflammation in arthritis.
Spel L., Martinon F., 2020/03. Immunological reviews, 294 (1) pp. 48-62. Peer-reviewed.
The gasdermins, a protein family executing cell death and inflammation.
Broz P., Pelegrín P., Shao F., 2020/03. Nature reviews. Immunology, 20 (3) pp. 143-157. Peer-reviewed.
Prisons and Prisoners in Europe 2019: Key Findings of the SPACE I report
Aebi Marcelo F., Tiago Mélanie M., 2020/02/24., Council of Europe; UNILCRIM Series.
Fusion Pores Live on the Edge.
Blokhuis E.M., D'Agostino M., Mayer A., Risselada H.J., 2020/02/20. The journal of physical chemistry letters, 11 (4) pp. 1204-1208. Peer-reviewed.
 
Allosteric activation of MALT1 by its ubiquitin-binding Ig3 domain.
Schairer R., Hall G., Zhang M., Cowan R., Baravalle R., Muskett F.W., Coombs P.J., Mpamhanga C., Hale L.R., Saxty B. et al., 2020/02/11. Proceedings of the National Academy of Sciences of the United States of America, 117 (6) pp. 3093-3102. Peer-reviewed.
Conjectures, refutations and the search for truths: Science, symbolic truths and the devil.
Dotto G.P., 2020/02/05. EMBO reports, 21 (2) pp. e49924. Peer-reviewed.
 
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein.
Cheng J., Klei L.R., Hubel N.E., Zhang M., Schairer R., Maurer L.M., Klei H.B., Kang H., Concel V.J., Delekta P.C. et al., 2020/02/03. The Journal of clinical investigation, 130 (2) pp. 1036-1051. Peer-reviewed.
Pannexin-1 promotes NLRP3 activation during apoptosis but is dispensable for canonical or noncanonical inflammasome activation.
Chen K.W., Demarco B., Broz P., 2020/02. European journal of immunology, 50 (2) pp. 170-177. Peer-reviewed.
 
Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5' and 3' flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion.
Csumita M., Csermely A., Horvath A., Nagy G., Monori F., Göczi L., Orbea H.A., Reith W., Széles L., 2020/01/24. Nucleic acids research, 48 (2) pp. 589-604. Peer-reviewed.
'Break the Chains 2015' community-based HIV prevention campaign for men who have sex with men in Switzerland: non-randomised evaluation and cost analysis.
Frey K., Lociciro S., Blank P., Schwenkglenks M., Dubois-Arber F., Rosenbrock R., Lehner A., Staub R., Derendinger S., Schmidt A.J. et al., 2020/01/21. BMJ open, 10 (1) pp. e032459. Peer-reviewed.
SNAREs, tethers and SM proteins: how to overcome the final barriers to membrane fusion?
Risselada H.J., Mayer A., 2020/01/17. The Biochemical journal, 477 (1) pp. 243-258. Peer-reviewed.
Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis.
Chen K.W., Demarco B., Broz P., 2020/01/15. The EMBO journal, 39 (2) pp. e103397. Peer-reviewed.
B-Cell Activating Factor Secreted by Neutrophils Is a Critical Player in Lung Inflammation to Cigarette Smoke Exposure.
Nascimento M., Huot-Marchand S., Gombault A., Panek C., Bourinet M., Fanny M., Savigny F., Schneider P., Le Bert M., Ryffel B. et al., 2020. Frontiers in immunology, 11 p. 1622. Peer-reviewed.
BAFF 60-mer, and Differential BAFF 60-mer Dissociating Activities in Human Serum, Cord Blood and Cerebrospinal Fluid.
Eslami M., Meinl E., Eibel H., Willen L., Donzé O., Distl O., Schneider H., Speiser D.E., Tsiantoulas D., Yalkinoglu Ö. et al., 2020. Frontiers in cell and developmental biology, 8 p. 577662. Peer-reviewed.
Behind the Scenes: Nod-Like Receptor X1 Controls Inflammation and Metabolism.
Snäkä T., Fasel N., 2020. Frontiers in cellular and infection microbiology, 10 p. 609812. Peer-reviewed.
 
Designs and Characterization of Subunit Ebola GP Vaccine Candidates: Implications for Immunogenicity.
Agnolon V., Kiseljak D., Wurm M.J., Wurm F.M., Foissard C., Gallais F., Wehrle S., Muñoz-Fontela C., Bellanger L., Correia B.E. et al., 2020. Frontiers in immunology, 11 p. 586595. Peer-reviewed.
 
Epitope Mapping and Fine Specificity of Human T and B Cell Responses for Novel Candidate Blood-Stage Malaria Vaccine P27A.
Geiger K.M., Guignard D., Yang C., Bikorimana J.P., Correia B.E., Houard S., Mkindi C., Daubenberger C.A., Spertini F., Corradin G. et al., 2020. Frontiers in immunology, 11 p. 412. Peer-reviewed.
 
H7N9 influenza split vaccine with SWE oil-in-water adjuvant greatly enhances cross-reactive humoral immunity and protection against severe pneumonia in ferrets.
de Jonge J., van Dijken H., de Heij F., Spijkers S., Mouthaan J., de Jong R., Roholl P., Adami E.A., Akamatsu M.A., Ho P.L. et al., 2020. NPJ vaccines, 5 p. 38. Peer-reviewed.
 
P. falciparum and P. vivax Orthologous Coiled-Coil Candidates for a Potential Cross-Protective Vaccine.
Ayadi I., Balam S., Audran R., Bikorimana J.P., Nebie I., Diakité M., Felger I., Tanner M., Spertini F., Corradin G. et al., 2020. Frontiers in immunology, 11 p. 574330. Peer-reviewed.
Phosphate Homeostasis - A Vital Metabolic Equilibrium Maintained Through the INPHORS Signaling Pathway.
Austin S., Mayer A., 2020. Frontiers in microbiology, 11 p. 1367. Peer-reviewed.
Therapeutic Potential of Targeting Malt1-Dependent TCR Downstream Signaling to Promote the Survival of MHC-Mismatched Allografts.
Govender L., Mikulic J., Wyss J.C., Gaide O., Thome M., Golshayan D., 2020. Frontiers in immunology, 11 p. 576651. Peer-reviewed.
Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca<sup>2+</sup>/P2X7 Receptor Signaling Axis.
Brenet M., Martínez S., Pérez-Nuñez R., Pérez L.A., Contreras P., Díaz J., Avalos A.M., Schneider P., Quest AFG, Leyton L., 2020. Frontiers in cell and developmental biology, 8 p. 592442. Peer-reviewed.
 
Crosstalk between SHH and FGFR Signaling Pathways Controls Tissue Invasion in Medulloblastoma.
Neve A., Migliavacca J., Capdeville C., Schönholzer M.T., Gries A., Ma M., Santhana Kumar K., Grotzer M., Baumgartner M., 2019/12/10. Cancers, 11 (12). Peer-reviewed.
 
Gender medicine and oncology: report and consensus of an ESMO workshop.
Wagner A.D., Oertelt-Prigione S., Adjei A., Buclin T., Cristina V., Csajka C., Coukos G., Dafni U., Dotto G.P., Ducreux M. et al., 2019/12/01. Annals of oncology, 30 (12) pp. 1914-1924. Peer-reviewed.
 
Efficacy of three innovative bacterin vaccines against experimental infection with Mycoplasma hyopneumoniae.
Matthijs AMF, Auray G., Boyen F., Schoos A., Michiels A., García-Nicolás O., Barut G.T., Barnier-Quer C., Jakob V., Collin N. et al., 2019/11/08. Veterinary research, 50 (1) p. 91. Peer-reviewed.
Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.
Kusano T., Ehirchiou D., Matsumura T., Chobaz V., Nasi S., Castelblanco M., So A., Lavanchy C., Acha-Orbea H., Nishino T. et al., 2019/10/28. Nature communications, 10 (1) p. 4904. Peer-reviewed.
 
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies.
Guièze R., Liu V.M., Rosebrock D., Jourdain A.A., Hernández-Sánchez M., Martinez Zurita A., Sun J., Ten Hacken E., Baranowski K., Thompson P.A. et al., 2019/10/14. Cancer cell, 36 (4) pp. 369-384.e13. Peer-reviewed.
No interactions between heparin and atacicept, an antagonist of B cell survival cytokines.
Kowalczyk-Quintas C., Willen D., Willen L., Golob M., Schuepbach-Mallepell S., Peter B., Eslami M., Vigolo M., Broly H., Samy E. et al., 2019/10. British journal of pharmacology, 176 (20) pp. 4019-4033. Peer-reviewed.
 
NCoR1: Putting the Brakes on the Dendritic Cell Immune Tolerance.
Ahad A., Stevanin M., Smita S., Mishra G.P., Gupta D., Waszak S., Sarkar U.A., Basak S., Gupta B., Acha-Orbea H. et al., 2019/09/27. iScience, 19 pp. 996-1011. Peer-reviewed.
ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis.
Scambler T., Jarosz-Griffiths H.H., Lara-Reyna S., Pathak S., Wong C., Holbrook J., Martinon F., Savic S., Peckham D., McDermott M.F., 2019/09/18. eLife, 8. Peer-reviewed.
 
Prenatal Treatment of X-Linked Hypohidrotic Ectodermal Dysplasia using Recombinant Ectodysplasin in a Canine Model.
Margolis C.A., Schneider P., Huttner K., Kirby N., Houser T.P., Wildman L., Grove G.L., Schneider H., Casal M.L., 2019/09. The Journal of pharmacology and experimental therapeutics, 370 (3) pp. 806-813. Peer-reviewed.
 
The regulatory network behind MHC class I expression.
Jongsma MLM, Guarda G., Spaapen R.M., 2019/09. Molecular immunology, 113 pp. 16-21. Peer-reviewed.
 
CSL controls telomere maintenance and genome stability in human dermal fibroblasts.
Bottoni G., Katarkar A., Tassone B., Ghosh S., Clocchiatti A., Goruppi S., Bordignon P., Jafari P., Tordini F., Lunardi T. et al., 2019/08/29. Nature communications, 10 (1) p. 3884. Peer-reviewed.
 
Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant.
Bordignon P., Bottoni G., Xu X., Popescu A.S., Truan Z., Guenova E., Kofler L., Jafari P., Ostano P., Röcken M. et al., 2019/08/27. Cell reports, 28 (9) pp. 2358-2372.e6. Peer-reviewed.
 
Immunogenicity of a recombinant fusion construct composed of intrinsically unstructured, low polymorphic segments derived from merozoite surface protein 2 and trophozoite exported protein 1.
Tiendrebeogo R.W., Spallek R., Oehlmann W., Singh M., Theisen M., Nebie I., Moret R., Roussilhon C., Corradin G., 2019/08/23. Vaccine, 37 (36) pp. 5332-5340. Peer-reviewed.
 
Reduced Renal Colonization and Enhanced Protection by Leptospiral Factor H Binding Proteins as a Multisubunit Vaccine Against Leptospirosis in Hamsters.
Techawiwattanaboon T., Barnier-Quer C., Palaga T., Jacquet A., Collin N., Sangjun N., Komanee P., Piboonpocanun S., Patarakul K., 2019/08/22. Vaccines, 7 (3). Peer-reviewed.
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis.
Collins S.C., Mikhaleva A., Vrcelj K., Vancollie V.E., Wagner C., Demeure N., Whitley H., Kannan M., Balz R., Anthony LFE et al., 2019/08/01. Nature communications, 10 (1) p. 3465. Peer-reviewed.
Sex Hormones and Anticancer Immunity.
Özdemir B.C., Dotto G.P., 2019/08/01. Clinical cancer research, 25 (15) pp. 4603-4610. Peer-reviewed.
 
NLRP6 Deficiency in CD4 T Cells Decreases T Cell Survival Associated with Increased Cell Death.
Radulovic K., Ayata C.K., Mak'Anyengo R., Lechner K., Wuggenig P., Kaya B., Hruz P., Gomez de Agüero M., Broz P., Weigmann B. et al., 2019/07/15. Journal of immunology, 203 (2) pp. 544-556. Peer-reviewed.
Immunofibroblasts are pivotal drivers of tertiary lymphoid structure formation and local pathology.
Nayar S., Campos J., Smith C.G., Iannizzotto V., Gardner D.H., Mourcin F., Roulois D., Turner J., Sylvestre M., Asam S. et al., 2019/07/02. Proceedings of the National Academy of Sciences of the United States of America, 116 (27) pp. 13490-13497. Peer-reviewed.
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts.
Schaeuble K., Cannelle H., Favre S., Huang H.Y., Oberle S.G., Speiser D.E., Zehn D., Luther S.A., 2019/07. PLoS biology, 17 (7) pp. e3000072. Peer-reviewed.
HVEM, a cosignaling molecular switch, and its interactions with BTLA, CD160 and LIGHT.
Rodriguez-Barbosa J.I., Schneider P., Weigert A., Lee K.M., Kim T.J., Perez-Simon J.A., Del Rio M.L., 2019/07. Cellular & molecular immunology, 16 (7) pp. 679-682. Peer-reviewed.
 
Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs.
Bernelin-Cottet C., Urien C., McCaffrey J., Collins D., Donadei A., McDaid D., Jakob V., Barnier-Quer C., Collin N., Bouguyon E. et al., 2019/06/29. Journal of controlled release, 308 pp. 14-28. Peer-reviewed.
A DNA-Modified Live Vaccine Prime-Boost Strategy Broadens the T-Cell Response and Enhances the Antibody Response against the Porcine Reproductive and Respiratory Syndrome Virus.
Bernelin-Cottet C., Urien C., Stubsrud E., Jakob V., Bouguyon E., Bordet E., Barc C., Boulesteix O., Contreras V., Barnier-Quer C. et al., 2019/06/14. Viruses, 11 (6). Peer-reviewed.
 
Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis.
Rath C.T., Schnellrath L.C., Damaso C.R., de Arruda L.B., Vasconcelos PFDC, Gomes C., Laurenti M.D., Calegari Silva T.C., Vivarini Á.C., Fasel N. et al., 2019/06. PLoS neglected tropical diseases, 13 (6) pp. e0007500. Peer-reviewed.
 
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Coll R.C., Hill J.R., Day C.J., Zamoshnikova A., Boucher D., Massey N.L., Chitty J.L., Fraser J.A., Jennings M.P., Robertson AAB et al., 2019/06. Nature chemical biology, 15 (6) pp. 556-559. Peer-reviewed.
 
TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.
Ronet C., Passelli K., Charmoy M., Scarpellino L., Myburgh E., Hauyon La Torre Y., Turco S., Mottram J.C., Fasel N., Luther S.A. et al., 2019/06. The Journal of investigative dermatology, 139 (6) pp. 1318-1328. Peer-reviewed.
IL-4Rα-Expressing B Cells Are Required for CXCL13 Production by Fibroblastic Reticular Cells.
Dubey L.K., Ludewig B., Luther S.A., Harris N.L., 2019/05/21. Cell Reports, 27 (8) pp. 2442-2458.e5. Peer-reviewed.
 
Phenazine-Embedded Copper(II) Complex as a Fluorescent Probe for the Detection of NO and HNO with a Bioimaging Application.
Islam ASM, Sasmal M., Maiti D., Dutta A., Ganguly S., Katarkar A., Gangopadhyay S., Ali M., 2019/05/20. ACS applied bio materials, 2 (5) pp. 1944-1955. Peer-reviewed.
Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly.
Chen K.W., Demarco B., Heilig R., Shkarina K., Boettcher A., Farady C.J., Pelczar P., Broz P., 2019/05/15. The EMBO journal, 38 (10). Peer-reviewed.
Detection of antisense protein (ASP) RNA transcripts in individuals infected with human immunodeficiency virus type 1 (HIV-1).
Mancarella A., Procopio F.A., Achsel T., De Crignis E., Foley B.T., Corradin G., Bagni C., Pantaleo G., Graziosi C., 2019/05. The Journal of general virology, 100 (5) pp. 863-876. Peer-reviewed.
Gender and sex-time to bridge the gap.
Dotto G.P., 2019/05. EMBO molecular medicine, 11 (5). Peer-reviewed.
 
Circulating microRNAs combined with PSA for accurate and non-invasive prostate cancer detection.
Mello-Grand M., Gregnanin I., Sacchetto L., Ostano P., Zitella A., Bottoni G., Oderda M., Marra G., Munegato S., Pardini B. et al., 2019/04/29. Carcinogenesis, 40 (2) pp. 246-253. Peer-reviewed.
Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia.
Del-Pozo J., MacIntyre N., Azar A., Headon D., Schneider P., Cheeseman M., 2019/04/25. Disease models & mechanisms, 12 (4). Peer-reviewed.
γ-Catenin-Dependent Signals Maintain BCR-ABL1<sup>+</sup> B Cell Acute Lymphoblastic Leukemia.
Luong-Gardiol N., Siddiqui I., Pizzitola I., Jeevan-Raj B., Charmoy M., Huang Y., Irmisch A., Curtet S., Angelov G.S., Danilo M. et al., 2019/04/15. Cancer cell, 35 (4) pp. 649-663.e10. Peer-reviewed.
 
A role for stromal autophagy in cancer-associated fibroblast activation.
Goruppi S., Clocchiatti A., Dotto G.P., 2019/04. Autophagy, 15 (4) pp. 738-739. Peer-reviewed.
 
Trends of incidence and survival of patients with chronic myelomonocytic leukemia between 1999 and 2014: A comparison between Swiss and American population-based cancer registries.
Benzarti S., Daskalakis M., Feller A., Bacher V.U., Schnegg-Kaufmann A., Rüfer A., Holbro A., Schmidt A., Benz R., Solenthaler M. et al., 2019/04. Cancer epidemiology, 59 pp. 51-57. Peer-reviewed.
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.
Niogret C., Miah SMS, Rota G., Fonta N.P., Wang H., Held W., Birchmeier W., Sexl V., Yang W., Vivier E. et al., 2019/03/29. Nature communications, 10 (1) p. 1444. Peer-reviewed.
Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus.
Marcandalli J., Fiala B., Ols S., Perotti M., de van der Schueren W., Snijder J., Hodge E., Benhaim M., Ravichandran R., Carter L. et al., 2019/03/07. Cell, 176 (6) pp. 1420-1431.e17. Peer-reviewed.
A proliferation-inducing ligand-mediated anti-inflammatory response of astrocytes in multiple sclerosis.
Baert L., Benkhoucha M., Popa N., Ahmed M.C., Manfroi B., Boutonnat J., Sturm N., Raguenez G., Tessier M., Casez O. et al., 2019/03. Annals of neurology, 85 (3) pp. 406-420. Peer-reviewed.
Divide to conquer: NLRP3 is activated on dispersed trans-Golgi network.
Chen K.W., Boucher D., Broz P., 2019/03. Cell research, 29 (3) pp. 181-182. Peer-reviewed.
First person – Christin Bissig
Bissig C., 2019/03/01. Journal of Cell Science, 132 (5) pp. jcs230466. Peer-reviewed.
 
Prevalence of oncogenic Human papillomavirus and genetic diversity in the L1 gene of HPV16 HPV 18 HPV31 and HPV33 found in women from Vojvodina Province Serbia.
Kovacevic G., Milosevic V., Knezevic P., Knezevic A., Knezevic I., Radovanov J., Nikolic N., Patic A., Petrovic V., Hrnjakovic Cvjetkovic I. et al., 2019/03. Biologicals, 58 pp. 57-63. Peer-reviewed.
 
Recognition of Intracellular Bacteria by Inflammasomes.
Broz P., 2019/03. Microbiology spectrum, 7 (2). Peer-reviewed.
Inhibition of NK Reactivity Against Solid Tumors by Platelet-Derived RANKL.
Clar K.L., Hinterleitner C., Schneider P., Salih H.R., Maurer S., 2019/02/26. Cancers, 11 (3). Peer-reviewed.
Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy.
Siddiqui I., Schaeuble K., Chennupati V., Fuertes Marraco S.A., Calderon-Copete S., Pais Ferreira D., Carmona S.J., Scarpellino L., Gfeller D., Pradervand S. et al., 2019/01/15. Immunity, 50 (1) pp. 195-211.e10. Peer-reviewed.
 
A Surface-Induced Asymmetric Program Promotes Tissue Colonization by Pseudomonas aeruginosa.
Laventie B.J., Sangermani M., Estermann F., Manfredi P., Planes R., Hug I., Jaeger T., Meunier E., Broz P., Jenal U., 2019/01/09. Cell host & microbe, 25 (1) pp. 140-152.e6. Peer-reviewed.
A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion.
Valoskova K., Biebl J., Roblek M., Emtenani S., Gyoergy A., Misova M., Ratheesh A., Reis-Rodrigues P., Shkarina K., Larsen ISB et al., 2019. eLife, 8 pp. e41801. Peer-reviewed.
 
An integrative protocol for the structure determination of the mouse ASC-PYD filament.
Mazur A., Broz P., Hiller S., 2019. Methods in enzymology, 625 pp. 205-222. Peer-reviewed.
Assay of Lipid Mixing and Fusion Pore Formation in the Fusion of Yeast Vacuoles.
D'Agostino M., Mayer A., 2019. Methods in molecular biology, 1860 pp. 253-262. Peer-reviewed.
Development of Sample-Adaptable Holders for Lightsheet Microscopy.
Laroche T., Burri O., Dubey L.K., Seitz A., 2019. Frontiers in Neuroanatomy, 13 p. 26. Peer-reviewed.
Erratum: Author Correction: System immunology-based identification of blood transcriptional modules correlating to antibody responses in sheep.
Braun R.O., Brunner L., Wyler K., Auray G., García-Nicolás O., Python S., Zumkehr B., Gaschen V., Stoffel M.H., Collin N. et al., 2019. NPJ vaccines, 4 p. 10. Peer-reviewed.
Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells.
Karrich J.J., Romera-Hernández M., Papazian N., Veenbergen S., Cornelissen F., Aparicio-Domingo P., Stenhouse F.H., Peddie C.D., Hoogenboezem R.M., den Hollander CWJ et al., 2019. European Journal of Immunology, 49 (2) pp. 290-301. Peer-reviewed.
Feather arrays are patterned by interacting signalling and cell density waves.
Ho WKW, Freem L., Zhao D., Painter K.J., Woolley T.E., Gaffney E.A., McGrew M.J., Tzika A., Milinkovitch M.C., Schneider P. et al., 2019. PLoS Biology, 17 (2) pp. e3000132. Peer-reviewed.
 
Isolation of Neutrophil Nuclei for Use in NETosis Assays
Boucher Dave, 2019. BIO-PROTOCOL, 9 (17).
Large-Scale 3-5 Hz Oscillation Constrains the Expression of Neocortical Fast Ripples in a Mouse Model of Mesial Temporal Lobe Epilepsy.
Sheybani L., van Mierlo P., Birot G., Michel C.M., Quairiaux C., 2019. eNeuro, 6 (1). Peer-reviewed.
Leishmania Parasite Quantification by Bioluminescence in Murine Models
Reverte Marta, Fasel Nicolas, 2019. BIO-PROTOCOL, 9 (22).
 
Leukotriene B<sub>4</sub> modulation of murine dendritic cells affects adaptive immunity.
Pires-Lapa M.A., Koga M.M., da Silva I.A., Filgueiras L.R., Jancar S., 2019. Prostaglandins & other Lipid Mediators, 141 pp. 34-39. Peer-reviewed.
Measuring the Activity of Plasma Membrane and Vacuolar Transporters in Yeast.
Cools M., Rompf M., Mayer A., André B., 2019. Methods in molecular biology, 2049 pp. 247-261. Peer-reviewed.
Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation.
Lara-Reyna S., Scambler T., Holbrook J., Wong C., Jarosz-Griffiths H.H., Martinon F., Savic S., Peckham D., McDermott M.F., 2019. Frontiers in immunology, 10 p. 1789. Peer-reviewed.
Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning.
Sadier A., Twarogowska M., Steklikova K., Hayden L., Lambert A., Schneider P., Laudet V., Hovorakova M., Calvez V., Pantalacci S., 2019. PLoS Biology, 17 (2) pp. e3000064. Peer-reviewed.
Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation.
Demarco B., Chen K.W., Broz P., 2019. Molecular & cellular oncology, 6 (4) p. 1610324. Peer-reviewed.
RNA-Seq Revealed Expression of Many Novel Genes Associated With Leishmania donovani Persistence and Clearance in the Host Macrophage
Shadab M., Das S., Banerjee A., Sinha R., Asad M., Kamran M., Maji M., Jha B., Deepthi M., Kumar M. et al., 2019. Frontiers in Cellular and Infection Microbiology, 9 p. 17. Peer-reviewed.
 
SHP-2 in Lymphocytes' Cytokine and Inhibitory Receptor Signaling.
Niogret C., Birchmeier W., Guarda G., 2019. Frontiers in immunology, 10 p. 2468. Peer-reviewed.
Systems Immunology Characterization of Novel Vaccine Formulations for Mycoplasma hyopneumoniae Bacterins.
Matthijs AMF, Auray G., Jakob V., García-Nicolás O., Braun R.O., Keller I., Bruggman R., Devriendt B., Boyen F., Guzman C.A. et al., 2019. Frontiers in immunology, 10 p. 1087. Peer-reviewed.
 
The mKate fluorescent protein expressed by Leishmania mexicana modifies the parasite immunopathogenicity in BALB/c mice.
Diupotex M., Martínez-Salazar M.B., Escalona-Montaño A.R., Zamora-Chimal J., Salaiza-Suazo N., Ruiz-Remigio A., Roldán-Salgado A., Aguirre-García M.M., Martínez-Calvillo S., Gaytán P. et al., 2019. Parasite Immunology, 41 (2) pp. e12608. Peer-reviewed.
TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes.
Staniek J., Lorenzetti R., Heller B., Janowska I., Schneider P., Unger S., Warnatz K., Seidl M., Venhoff N., Thiel J. et al., 2019. Frontiers in immunology, 10 p. 951. Peer-reviewed.
 
Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation.
Clocchiatti A., Ghosh S., Procopio M.G., Mazzeo L., Bordignon P., Ostano P., Goruppi S., Bottoni G., Katarkar A., Levesque M. et al., 2018/12/03. The Journal of clinical investigation, 128 (12) pp. 5531-5548. Peer-reviewed.
Deletion of Interleukin-4 Receptor Alpha-Responsive Keratinocytes in BALB/c Mice Does Not Alter Susceptibility to Cutaneous Leishmaniasis.
Govender M., Hurdayal R., Martinez-Salazar B., Gqada K., Pillay S., Gcanga L., Passelli K., Nieuwenhuizen N.E., Tacchini-Cottier F., Guler R. et al., 2018/12. Infection and immunity, 86 (12) pp. e00710-18. Peer-reviewed.
 
Gasdermin D opens the way for NETs.
Spel L., Martinon F., 2018/12. Nature reviews. Rheumatology, 14 (12) pp. 690-692. Peer-reviewed.
Guanylate-binding protein 5 licenses caspase-11 for Gasdermin-D mediated host resistance to Brucella abortus infection.
Cerqueira D.M., Gomes MTR, Silva ALN, Rungue M., Assis NRG, Guimarães E.S., Morais S.B., Broz P., Zamboni D.S., Oliveira S.C., 2018/12. PLoS pathogens, 14 (12) pp. e1007519. Peer-reviewed.
The criminal association of Leishmania parasites and viruses.
Rossi M., Fasel N., 2018/12. Current opinion in microbiology, 46 pp. 65-72. Peer-reviewed.
BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.
Chauhan D., Bartok E., Gaidt M.M., Bock F.J., Herrmann J., Seeger J.M., Broz P., Beckmann R., Kashkar H., Tait SWG et al., 2018/11/27. Cell reports, 25 (9) pp. 2354-2368.e5. Peer-reviewed.
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation.
Rühl S., Shkarina K., Demarco B., Heilig R., Santos J.C., Broz P., 2018/11/23. Science, 362 (6417) pp. 956-960. Peer-reviewed.
B Cell-Activating Factor Neutralization Aggravates Atherosclerosis.
Tsiantoulas D., Sage A.P., Göderle L., Ozsvar-Kozma M., Murphy D., Porsch F., Pasterkamp G., Menche J., Schneider P., Mallat Z. et al., 2018/11/13. Circulation, 138 (20) pp. 2263-2273. Peer-reviewed.
Oestrogen receptor α AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium.
Cagnet S., Ataca D., Sflomos G., Aouad P., Schuepbach-Mallepell S., Hugues H., Krust A., Ayyanan A., Scabia V., Brisken C., 2018/11/09. Nature communications, 9 (1) p. 4723. Peer-reviewed.
 
Sensing of invading pathogens by GBPs: At the crossroads between cell-autonomous and innate immunity.
Santos J.C., Broz P., 2018/10. Journal of leukocyte biology, 104 (4) pp. 729-735. Peer-reviewed.
SNARE-mediated membrane fusion arrests at pore expansion to regulate the volume of an organelle.
D'Agostino M., Risselada H.J., Endter L.J., Comte-Miserez V., Mayer A., 2018/10/01. The EMBO journal, 37 (19). Peer-reviewed.
Therapeutic implications of NK cell regulation of allogeneic CD8 T cell-mediated immune responses stimulated through the direct pathway of antigen presentation in transplantation.
Rodriguez-Barbosa J.I., Ferreras M.C., Buhler L., Jones N.D., Schneider P., Perez-Simon J.A., Del Rio M.L., 2018/10. mAbs, 10 (7) pp. 1030-1044. Peer-reviewed.
Autophagy Controls CSL/RBPJκ Stability through a p62/SQSTM1-Dependent Mechanism.
Goruppi S., Jo S.H., Laszlo C., Clocchiatti A., Neel V., Dotto G.P., 2018/09/18. Cell reports, 24 (12) pp. 3108-3114.e4. Peer-reviewed.
Attenuation of Mammary Gland Dysplasia and Feeding Difficulties in Tabby Mice by Fetal Therapy.
Wahlbuhl M., Schuepbach-Mallepell S., Kowalczyk-Quintas C., Dick A., Fahlbusch F.B., Schneider P., Schneider H., 2018/09. Journal of mammary gland biology and neoplasia, 23 (3) pp. 125-138. Peer-reviewed.
CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo.
Mellett M., Meier B., Mohanan D., Schairer R., Cheng P., Satoh T.K., Kiefer B., Ospelt C., Nobbe S., Thome M. et al., 2018/09. The Journal of investigative dermatology, 138 (9) pp. 2010-2023. Peer-reviewed.
Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.
Chen K.W., Monteleone M., Boucher D., Sollberger G., Ramnath D., Condon N.D., von Pein J.B., Broz P., Sweet M.J., Schroder K., 2018/08/24. Science immunology, 3 (26) pp. eaar6676. Peer-reviewed.
B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD).
Bruzzì S., Sutti S., Giudici G., Burlone M.E., Ramavath N.N., Toscani A., Bozzola C., Schneider P., Morello E., Parola M. et al., 2018/08/20. Free radical biology & medicine, 124 pp. 249-259. Peer-reviewed.
A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate.
Jamilloux Y., Lagrange B., Di Micco A., Bourdonnay E., Provost A., Tallant R., Henry T., Martinon F., 2018/08/10. The Journal of biological chemistry, 293 (32) pp. 12563-12575. Peer-reviewed.
Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.
Robak O.H., Heimesaat M.M., Kruglov A.A., Prepens S., Ninnemann J., Gutbier B., Reppe K., Hochrein H., Suter M., Kirschning C.J. et al., 2018/08/01. The Journal of clinical investigation, 128 (8) pp. 3535-3545. Peer-reviewed.
RNA fusions involving CD28 are rare in peripheral T-cell lymphomas and concentrate mainly in those derived from follicular helper T cells.
Vallois D., Dupuy A., Lemonnier F., Allen G., Missiaglia E., Fataccioli V., Ortonne N., Clavert A., Delarue R., Rousselet M.C. et al., 2018/08. Haematologica, 103 (8) pp. e360-e363. Peer-reviewed.
 
The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.
Castro W., Chelbi S.T., Niogret C., Ramon-Barros C., Welten SPM, Osterheld K., Wang H., Rota G., Morgado L., Vivier E. et al., 2018/08. Nature immunology, 19 (8) pp. 809-820. Peer-reviewed.
Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7<sup>+</sup> Progenitors to the Thymus.
Cosway E.J., Ohigashi I., Schauble K., Parnell S.M., Jenkinson W.E., Luther S., Takahama Y., Anderson G., 2018/07/15. Journal of immunology, 201 (2) pp. 516-523. Peer-reviewed.
CART cells are prone to Fas- and DR5-mediated cell death.
Tschumi B.O., Dumauthioz N., Marti B., Zhang L., Lanitis E., Irving M., Schneider P., Mach J.P., Coukos George, Romero P. et al., 2018/07/13. Journal for immunotherapy of cancer, 6 (1) p. 71. Peer-reviewed.
 
Analysis of cytokine immune response profile in response to inflammatory stimuli in mice with genetic defects in fetal and adult hemoglobin chain expression.
Khatri I., Alexander C., Brandenburg K., Chen Z., Heini A., Heumann D., Mach J.P., Mazzoli V., Rietschel E., Terskikh A. et al., 2018/07. The pharmacogenomics journal, 18 (4) pp. 546-555. Peer-reviewed.
Inflammation initiated by stressed organelles.
Martinon F., 2018/07. Joint, bone, spine, 85 (4) pp. 423-428. Peer-reviewed.
Leishmania amazonensis downregulates macrophage iNOS expression via Histone Deacetylase 1 (HDAC1): a novel parasite evasion mechanism.
Calegari-Silva T.C., Vivarini Á.C., Pereira RMS, Dias-Teixeira K.L., Rath C.T., Pacheco ASS, Silva GBL, Pinto CAS, Dos Santos J.V., Saliba A.M. et al., 2018/07. European journal of immunology, 48 (7) pp. 1188-1198. Peer-reviewed.
 
Corrigendum to "An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression" [Int. Immunopharmacol. 50 (2017) 69-76].
Gorczynski R.M., Alexander C., Brandenburg K., Chen Z., Heini A., Neumann D., Mach J.P., Rietschel E.T., Terskikh A., Ulmer A.J. et al., 2018/06. International immunopharmacology, 59 p. 414. Peer-reviewed.
 
Corrigendum to "Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis" [Int. Immunopharmacol. 57 (2018) 112-120].
Kos O., Alexander C., Brandenburg K., Chen Z., Heini A., Heumann D., Khatri I., Mach J.P., Rietschel E.T., Terskikh A. et al., 2018/06. International immunopharmacology, 59 p. 413. Peer-reviewed.
Notch-effector CSL promotes squamous cell carcinoma by repressing histone demethylase KDM6B.
Al Labban D., Jo S.H., Ostano P., Saglietti C., Bongiovanni M., Panizzon R., Dotto G.P., 2018/06/01. The Journal of clinical investigation, 128 (6) pp. 2581-2599. Peer-reviewed.
 
Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma.
Battistello E., Katanayeva N., Dheilly E., Tavernari D., Donaldson M.C., Bonsignore L., Thome M., Christie A.L., Murakami M.A., Michielin O. et al., 2018/05/24. Blood, 131 (21) pp. 2345-2356. Peer-reviewed.
 
Single-Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche-Associated Heterogeneity.
Rodda L.B., Lu E., Bennett M.L., Sokol C.L., Wang X., Luther S.A., Barres B.A., Luster A.D., Ye C.J., Cyster J.G., 2018/05/15. Immunity, 48 (5) pp. 1014-1028.e6. Peer-reviewed.
Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue.
Fleige H., Bosnjak B., Permanyer M., Ristenpart J., Bubke A., Willenzon S., Sutter G., Luther S.A., Förster R., 2018/04/17. Cell reports, 23 (3) pp. 783-795. Peer-reviewed.
Assay for high-throughput screening of inhibitors of the ASC-PYD inflammasome core filament
Sborgi Lorenzo, Ude Johanna, Dick Mathias S., Vesin Jonathan, Chambon Marc, Turcatti Gerardo, Broz Petr, Hiller Sebastian, 2018/04/09. Cell Stress, 2 (4) pp. 82-90.
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Vigolo M., Chambers M.G., Willen L., Chevalley D., Maskos K., Lammens A., Tardivel A., Das D., Kowalczyk-Quintas C., Schuepbach-Mallepell S. et al., 2018/03/23. Nature communications, 9 (1) p. 1199. Peer-reviewed.
 
LPS targets host guanylate-binding proteins to the bacterial outer membrane for non-canonical inflammasome activation.
Santos J.C., Dick M.S., Lagrange B., Degrandi D., Pfeffer K., Yamamoto M., Meunier E., Pelczar P., Henry T., Broz P., 2018/03/15. The EMBO journal, 37 (6) pp. 1-19. Peer-reviewed.
How to master the host immune system? Leishmania parasites have the solutions!
Rossi M., Fasel N., 2018/03/10. International immunology, 30 (3) pp. 103-111. Peer-reviewed.
 
Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production both in vitro and in a mouse model of inflammation.
Castelblanco M., Lugrin J., Ehirchiou D., Nasi S., Ishii I., So A., Martinon F., Busso N., 2018/02/16. The Journal of biological chemistry, 293 (7) pp. 2546-2557. Peer-reviewed.
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.
Chen J., Guccini I., Di Mitri D., Brina D., Revandkar A., Sarti M., Pasquini E., Alajati A., Pinton S., Losa M. et al., 2018/02. Nature genetics, 50 (2) pp. 219-228. Peer-reviewed.
 
EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation
Silva Joana, Aivio Suvi, Knobel Philip A., Bailey Laura J., Casali Andreu, Vinaixa Maria, Garcia-Cao Isabel, Coyaud Étienne, Jourdain Alexis A., Pérez-Ferreros Pablo et al., 2018/02. Nature Cell Biology, 20 (2) pp. 162-174. Peer-reviewed.
 
Function and mechanism of the pyrin inflammasome.
Heilig R., Broz P., 2018/02. European journal of immunology, 48 (2) pp. 230-238. Peer-reviewed.
The Immune Checkpoint Modulator OX40 and Its Ligand OX40L in NK-Cell Immunosurveillance and Acute Myeloid Leukemia
Nuebling Tina, Schumacher Carla Emilia, Hofmann Martin, Hagelstein Ilona, Schmiedel Benjamin Joachim, Maurer Stefanie, Federmann Birgit, Rothfelder Kathrin, Roerden Malte, Dörfel Daniela et al., 2018/02. Cancer Immunology Research, 6 (2) pp. 209-221.
Down selecting adjuvanted vaccine formulations: a comparative method for harmonized evaluation.
Younis S.Y., Barnier-Quer C., Heuking S., Sommandas V., Brunner L., Vd Werff N., Dubois P., Friede M., Kocken C., Collin N. et al., 2018/01/31. BMC immunology, 19 (1) p. 6. Peer-reviewed.
 
Mechanisms and Consequences of Inflammasome Activation.
Schroder K., Kanneganti T.D., Shao F., Broz P., 2018/01/19. Journal of molecular biology, 430 (2) pp. 131-132. Peer-reviewed.
Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite <i>Leishmania</i>.
Grybchuk D., Akopyants N.S., Kostygov A.Y., Konovalovas A., Lye L.F., Dobson D.E., Zangger H., Fasel N., Butenko A., Frolov A.O. et al., 2018/01/16. Proceedings of the National Academy of Sciences of the United States of America, 115 (3) pp. E506-E515. Peer-reviewed.
A Combination of Approved Antibodies Overcomes Resistance of Lung Cancer to Osimertinib by Blocking Bypass Pathways.
Romaniello D., Mazzeo L., Mancini M., Marrocco I., Noronha A., Kreitman M., Srivastava S., Ghosh S., Lindzen M., Salame T.M. et al., 2018. Clinical Cancer Research, 24 (22) pp. 5610-5621. Peer-reviewed.
A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.
Tan J., Sack B.K., Oyen D., Zenklusen I., Piccoli L., Barbieri S., Foglierini M., Fregni C.S., Marcandalli J., Jongo S. et al., 2018. Nature Medicine, 24 (4) pp. 401-407. Peer-reviewed.
 
A rhodamine hydrazide–4-nitroindole-3-carboxaldehyde based turn on Hg2+ chemosensor: cytoplasmic live cell imaging, logic gate and memory device applications and computational studies
Bhowmick R., Musha Islam A.S., Sasmal M., Katarkar A., Ali M., 2018. Journal of Coordination Chemistry, 71 (11-13) pp. 2065-2081.
A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis.
Wang C., Dulal P., Zhou X., Xiang Z., Goharriz H., Banyard A., Green N., Brunner L., Ventura R., Collin N. et al., 2018. PLoS Neglected Tropical Diseases, 12 (10) pp. e0006870. Peer-reviewed.
Absence of MHC-II expression by lymph node stromal cells results in autoimmunity.
Dubrot J., Duraes F.V., Harlé G., Schlaeppi A., Brighouse D., Madelon N., Göpfert C., Stokar-Regenscheit N., Acha-Orbea H., Reith W. et al., 2018. Life Science Alliance, 1 (6) pp. e201800164. Peer-reviewed.
Correction to: CART cells are prone to Fas- and DR5-mediated cell death.
Tschumi B.O., Dumauthioz N., Marti B., Zhang L., Lanitis E., Irving M., Schneider P., Mach J.P., Coukos G., Romero P. et al., 2018. Journal for Immunotherapy of Cancer, 6 (1) p. 92. Peer-reviewed.
Development of a semi-automated image-based high-throughput drug screening system.
Eren R.O., Kopelyanskiy D., Moreau D., Chapalay J.B., Chambon M., Turcatti G., Lye L.F., Beverley S.M., Fasel N., 2018/01/01. Frontiers in bioscience, 10 pp. 242-253. Peer-reviewed.
Establishment and Characterization of a Functionally Competent Type 2 Conventional Dendritic Cell Line.
Pigni M., Ashok D., Stevanin M., Acha-Orbea H., 2018. Frontiers in immunology, 9 p. 1912. Peer-reviewed.
Functions of the <i>Dictyostelium</i> LIMP-2 and CD36 homologues in bacteria uptake, phagolysosome biogenesis and host cell defence.
Sattler N., Bosmani C., Barisch C., Guého A., Gopaldass N., Dias M., Leuba F., Bruckert F., Cosson P., Soldati T., 2018. Journal of Cell Science, 131 (17). Peer-reviewed.
 
Global Ion Suppression Limits the Potential of Mass Spectrometry Based Phosphoproteomics.
Dreier R.F., Ahrné E., Broz P., Schmidt A., 2018. Journal of Proteome Research, 18 (1) pp. 493-507. Peer-reviewed.
Guidelines and recommendations on yeast cell death nomenclature
Carmona-Gutierez D, Fasel N, 2018. Microbial Cell, 5 (1) pp. 4-31. Peer-reviewed.
Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling.
Juilland M., Thome M., 2018. Frontiers in immunology, 9 p. 1927. Peer-reviewed.
 
Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis.
Huang H.Y., Rivas-Caicedo A., Renevey F., Cannelle H., Peranzoni E., Scarpellino L., Hardie D.L., Pommier A., Schaeuble K., Favre S. et al., 2018. Proceedings of the National Academy of Sciences of the United States of America, 115 (29) pp. E6826-E6835. Peer-reviewed.
Importance of EMT Factor ZEB1 in cDC1 "MutuDC Line" Mediated Induction of Th1 Immune Response.
Smita S., Ahad A., Ghosh A., Biswas V.K., Koga M.M., Gupta B., Acha-Orbea H., Raghav S.K., 2018. Frontiers in immunology, 9 p. 2604. Peer-reviewed.
Importance of polyphosphate in the <i>Leishmania</i> life cycle.
Kohl K., Zangger H., Rossi M., Isorce N., Lye L.F., Owens K.L., Beverley S.M., Mayer A., Fasel N., 2018. Microbial Cell, 5 (8) pp. 371-384. Peer-reviewed.
Inhibition of Membrane-Bound BAFF by the Anti-BAFF Antibody Belimumab.
Kowalczyk-Quintas C., Chevalley D., Willen L., Jandus C., Vigolo M., Schneider P., 2018. Frontiers in immunology, 9 p. 2698. Peer-reviewed.
Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.
Monteleone M., Stanley A.C., Chen K.W., Brown D.L., Bezbradica J.S., von Pein J.B., Holley C.L., Boucher D., Shakespear M.R., Kapetanovic R. et al., 2018. Cell Reports, 24 (6) pp. 1425-1433. Peer-reviewed.
Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice.
Wilson A., Fu H., Schiffrin M., Winkler C., Koufany M., Jouzeau J.Y., Bonnet N., Gilardi F., Renevey F., Luther S.A. et al., 2018. Frontiers in immunology, 9 p. 2573. Peer-reviewed.
Leishmania guyanensis parasites block the activation of the inflammasome by inhibiting maturation of IL-1β.
Hartley M.A., Eren R.O., Rossi M., Prevel F., Castiglioni P., Isorce N., Desponds C., Lye L.F., Beverley S.M., Drexler S.K. et al., 2018. Microbial Cell, 5 (3) pp. 137-149. Peer-reviewed.
MALT1 protease activity in primary effusion lymphoma.
Juilland M., Bonsignore L., Thome M., 2018. Oncotarget, 9 (16) pp. 12542-12543. Peer-reviewed.
Mobilizable Plasmids for Tunable Gene Expression in Francisella novicida.
Brodmann M., Heilig R., Broz P., Basler M., 2018. Frontiers in cellular and infection microbiology, 8 p. 284. Peer-reviewed.
Multiple roles of lymphatic vessels in peripheral lymph node development.
Bovay E., Sabine A., Prat-Luri B., Kim S., Son K., Willrodt A.H., Olsson C., Halin C., Kiefer F., Betsholtz C. et al., 2018. The Journal of Experimental Medicine, 215 (11) pp. 2760-2777. Peer-reviewed.
Neutrophils enhance early Trypanosoma brucei infection onset.
Caljon G., Mabille D., Stijlemans B., De Trez C., Mazzone M., Tacchini-Cottier F., Malissen M., A Van Ginderachter J., Magez S., De Baetselier P. et al., 2018. Scientific Reports, 8 (1) p. 11203. Peer-reviewed.
 
Nitric Oxide Sensing through 1,2,3,4-Oxatriazole Formation from Acylhydrazide: A Kinetic Study.
Islam ASM, Bhowmick R., Chandra Garain B., Katarkar A., Ali M., 2018. The Journal of Organic Chemistry, 83 (21) pp. 13287-13295. Peer-reviewed.
Prenatal Correction of X-Linked Hypohidrotic Ectodermal Dysplasia.
Schneider H., Faschingbauer F., Schuepbach-Mallepell S., Körber I., Wohlfart S., Dick A., Wahlbuhl M., Kowalczyk-Quintas C., Vigolo M., Kirby N. et al., 2018. The New England Journal of Medicine, 378 (17) pp. 1604-1610. Peer-reviewed.
 
Regulation of fetal hemoglobin expression during hematopoietic stem cell development and its importance in bone metabolism and osteoporosis.
Kos O., Alexander C., Brandenburg K., Chen Z., Heini A., Heumann D., Khatri I., Mach J.P., Rietschel E.T., Tersikh A. et al., 2018. International Immunopharmacology, 57 pp. 112-120. Peer-reviewed.
Resistance of Leishmania (Viannia) Panamensis to Meglumine Antimoniate or Miltefosine Modulates Neutrophil Effector Functions.
Regli I.B., Fernández O.L., Martínez-Salazar B., Gómez M.A., Saravia N.G., Tacchini-Cottier F., 2018. Frontiers in Immunology, 9 p. 3040. Peer-reviewed.
Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.
Chennupati V., Veiga D.F., Maslowski K.M., Andina N., Tardivel A., Yu E.C., Stilinovic M., Simillion C., Duchosal M.A., Quadroni M. et al., 2018. The Journal of Clinical Investigation, 128 (4) pp. 1597-1614. Peer-reviewed.
Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo.
Rota G., Niogret C., Dang A.T., Barros C.R., Fonta N.P., Alfei F., Morgado L., Zehn D., Birchmeier W., Vivier E. et al., 2018. Cell Reports, 23 (1) pp. 39-49. Peer-reviewed.
System immunology-based identification of blood transcriptional modules correlating to antibody responses in sheep.
Braun R.O., Brunner L., Wyler K., Auray G., García-Nicolás O., Python S., Zumkehr B., Gaschen V., Stoffel M.H., Collin N. et al., 2018. NPJ vaccines, 3 p. 41. Peer-reviewed.
The AIM2 inflammasome: Sensor of pathogens and cellular perturbations.
Lugrin J., Martinon F., 2018/01. Immunological reviews, 281 (1) pp. 99-114. Peer-reviewed.
 
The Gasdermin-D pore acts as a conduit for IL-1β secretion in mice.
Heilig R., Dick M.S., Sborgi L., Meunier E., Hiller S., Broz P., 2018. European Journal of Immunology, 48 (4) pp. 584-592. Peer-reviewed.
The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity.
Schneider K.S., Groß C.J., Dreier R.F., Saller B.S., Mishra R., Gorka O., Heilig R., Meunier E., Dick M.S., Ćiković T. et al., 2017/12/26. Cell reports, 21 (13) pp. 3846-3859. Peer-reviewed.
Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis.
Dias-Teixeira K.L., Calegari-Silva T.C., Medina J.M., Vivarini Á.C., Cavalcanti Á., Teteo N., Santana AKM, Real F., Gomes C.M., Pereira RMS et al., 2017/12/06. Scientific reports, 7 (1) p. 17074. Peer-reviewed.
Magnesium uptake by connecting fluid-phase endocytosis to an intracellular inorganic cation filter.
Klompmaker S.H., Kohl K., Fasel N., Mayer A., 2017/12/01. Nature communications, 8 (1) p. 1879. Peer-reviewed.
A tethering complex drives the terminal stage of SNARE-dependent membrane fusion.
D'Agostino M., Risselada H.J., Lürick A., Ungermann C., Mayer A., 2017/11/30. Nature, 551 (7682) pp. 634-638. Peer-reviewed.
Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.
Schaeuble K., Britschgi M.R., Scarpellino L., Favre S., Xu Y., Koroleva E., Lissandrin TKA, Link A., Matloubian M., Ware C.F. et al., 2017/11/28. Cell reports, 21 (9) pp. 2500-2514. Peer-reviewed.
Survival Mechanisms Used by Some Leishmania Species to Escape Neutrophil Killing
Regli I.B., Passelli K., Hurrell B.P., Tacchini-Cottier F., 2017/11/16. Frontiers in Immunology, 8 p. 1558. Peer-reviewed.
The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.
Jourdain A.A., Popow J., de la Fuente M.A., Martinou J.C., Anderson P., Simarro M., 2017/11/02. Nucleic acids research, 45 (19) pp. 10941-10947. Peer-reviewed.
Membrane scission driven by the PROPPIN Atg18
Navin Gopaldass, Bruno Fauvet, Hilal Lashuel, Aurélien Roux, Andreas Mayer, 2017/10/13. The EMBO Journal.
Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies.
Feichtinger R.G., Oláhová M., Kishita Y., Garone C., Kremer L.S., Yagi M., Uchiumi T., Jourdain A.A., Thompson K., D'Souza A.R. et al., 2017/10/05. American journal of human genetics, 101 (4) pp. 525-538. Peer-reviewed.
 
Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis.
Jain V., Yogavel M., Kikuchi H., Oshima Y., Hariguchi N., Matsumoto M., Goel P., Touquet B., Jumani R.S., Tacchini-Cottier F. et al., 2017/10/03. Structure, 25 (10) pp. 1495-1505.e6. Peer-reviewed.
α<sub>V</sub>β<sub>3</sub> Integrin regulates astrocyte reactivity.
Lagos-Cabré R., Alvarez A., Kong M., Burgos-Bravo F., Cárdenas A., Rojas-Mancilla E., Pérez-Nuñez R., Herrera-Molina R., Rojas F., Schneider P. et al., 2017/09/29. Journal of neuroinflammation, 14 (1) p. 194. Peer-reviewed.
The ULK3 Kinase Is Critical for Convergent Control of Cancer-Associated Fibroblast Activation by CSL and GLI.
Goruppi S., Procopio M.G., Jo S., Clocchiatti A., Neel V., Dotto G.P., 2017/09/05. Cell reports, 20 (10) pp. 2468-2479. Peer-reviewed.
 
An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression.
Gorczynski R.M., Alexander C., Brandenburg K., Chen Z., Heini A., Neumann D., Mach J.P., Rietschel E.T., Tersikh A., Ulmer A.J. et al., 2017/09. International immunopharmacology, 50 pp. 69-76. Peer-reviewed.
Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation.
Lee S.H., Wang X., Kim S.H., Kim Y., Rodriguez-Puebla M.L., 2017/09. Oncology letters, 14 (3) pp. 2723-2734. Peer-reviewed.
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis.
Dubey L.K., Karempudi P., Luther S.A., Ludewig B., Harris N.L., 2017/08/28. Nature communications, 8 (1) p. 367. Peer-reviewed.
The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin.
Deloizy C., Fossum E., Barnier-Quer C., Urien C., Chrun T., Duval A., Codjovi M., Bouguyon E., Maisonnasse P., Hervé P.L. et al., 2017/08/09. Scientific reports, 7 (1) p. 7639. Peer-reviewed.
 
CLIC, a tool for expanding biological pathways based on co-expression across thousands of datasets
Yang Li, Alexis A. Jourdain, Sarah E. Calvo, Jun S. Liu, Vamsi K. Mootha, 2017/07/18. PLOS Computational Biology. Peer-reviewed.
Sirtuin 3 deficiency does not alter host defenses against bacterial and fungal infections.
Ciarlo E., Heinonen T., Lugrin J., Acha-Orbea H., Le Roy D., Auwerx J., Roger T., 2017/06/20. Scientific reports, 7 (1) p. 3853. Peer-reviewed.
Distinct pathophysiological cytokine profiles for discrimination between autoimmune pancreatitis, chronic pancreatitis, and pancreatic ductal adenocarcinoma.
Ghassem-Zadeh S., Gaida M.M., Szanyi S., Acha-Orbea H., Frossard J.L., Hinz U., Hackert T., Strobel O., Felix K., 2017/06/02. Journal of translational medicine, 15 (1) p. 126. Peer-reviewed.
FASTKD1 and FASTKD4 have opposite effects on expression of specific mitochondrial RNAs, depending upon their endonuclease-like RAP domain.
Boehm E., Zaganelli S., Maundrell K., Jourdain A.A., Thore S., Martinou J.C., 2017/06/02. Nucleic acids research, 45 (10) pp. 6135-6146. Peer-reviewed.
Replicating viral vector platform exploits alarmin signals for potent CD8<sup>+</sup> T cell-mediated tumour immunotherapy.
Kallert S.M., Darbre S., Bonilla W.V., Kreutzfeldt M., Page N., Müller P., Kreuzaler M., Lu M., Favre S., Kreppel F. et al., 2017/05/26. Nature communications, 8 p. 15327. Peer-reviewed.
Type I interferons induced by endogenous or exogenous viral infections promote metastasis and relapse of leishmaniasis.
Rossi M., Castiglioni P., Hartley M.A., Eren R.O., Prével F., Desponds C., Utzschneider D.T., Zehn D., Cusi M.G., Kuhlmann F.M. et al., 2017/05/09. Proceedings of the National Academy of Sciences of the United States of America, 114 (19) pp. 4987-4992. Peer-reviewed.
Ppn2, a novel Zn2+-dependent polyphosphatase in the acidocalcisome-like yeast vacuole.
Gerasimaitė R., Mayer A., 2017/05/01. Journal of cell science, 130 (9) pp. 1625-1636. Peer-reviewed.
 
TAT-RasGAP317-326 Enhances Radiosensitivity of Human Carcinoma Cell Lines In Vitro and In Vivo through Promotion of Delayed Mitotic Cell Death.
Tsoutsou P., Annibaldi A., Viertl D., Ollivier J., Buchegger F., Vozenin M.C., Bourhis J., Widmann C., Matzinger O., 2017/05. Radiation research, 187 (5) pp. 562-569. Peer-reviewed.
Partagez:
Unicentre - CH-1015 Lausanne
Suisse
Tél. +41 21 692 11 11
Swiss University